Amino acid dipepetide frequency for Chlamydotis macqueenii (Macqueen s bustard)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.615AlaAla: 5.615 ± 0.061	1.336AlaCys: 1.336 ± 0.021	3.01AlaAsp: 3.01 ± 0.029	4.668AlaGlu: 4.668 ± 0.051	2.645AlaPhe: 2.645 ± 0.031	3.838AlaGly: 3.838 ± 0.047	1.354AlaHis: 1.354 ± 0.021	3.114AlaIle: 3.114 ± 0.034	3.804AlaLys: 3.804 ± 0.04	6.389AlaLeu: 6.389 ± 0.059	1.525AlaMet: 1.525 ± 0.022	2.26AlaAsn: 2.26 ± 0.029	2.806AlaPro: 2.806 ± 0.035	2.717AlaGln: 2.717 ± 0.034	2.886AlaArg: 2.886 ± 0.03	5.194AlaSer: 5.194 ± 0.05	3.362AlaThr: 3.362 ± 0.038	4.905AlaVal: 4.905 ± 0.041	0.693AlaTrp: 0.693 ± 0.016	1.674AlaTyr: 1.674 ± 0.02	0.001AlaXaa: 0.001 ± 0.0
Cys	1.161CysAla: 1.161 ± 0.021	0.667CysCys: 0.667 ± 0.016	1.051CysAsp: 1.051 ± 0.02	1.29CysGlu: 1.29 ± 0.027	0.95CysPhe: 0.95 ± 0.02	1.413CysGly: 1.413 ± 0.024	0.625CysHis: 0.625 ± 0.016	1.151CysIle: 1.151 ± 0.024	1.347CysLys: 1.347 ± 0.024	2.19CysLeu: 2.19 ± 0.033	0.468CysMet: 0.468 ± 0.012	0.921CysAsn: 0.921 ± 0.018	1.193CysPro: 1.193 ± 0.024	1.083CysGln: 1.083 ± 0.022	1.213CysArg: 1.213 ± 0.022	2.029CysSer: 2.029 ± 0.03	1.203CysThr: 1.203 ± 0.018	1.363CysVal: 1.363 ± 0.021	0.297CysTrp: 0.297 ± 0.01	0.709CysTyr: 0.709 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	2.852AspAla: 2.852 ± 0.027	1.112AspCys: 1.112 ± 0.02	2.894AspAsp: 2.894 ± 0.037	3.711AspGlu: 3.711 ± 0.045	2.312AspPhe: 2.312 ± 0.025	3.199AspGly: 3.199 ± 0.037	1.18AspHis: 1.18 ± 0.019	2.966AspIle: 2.966 ± 0.034	2.853AspLys: 2.853 ± 0.034	5.062AspLeu: 5.062 ± 0.039	1.157AspMet: 1.157 ± 0.02	1.975AspAsn: 1.975 ± 0.026	2.639AspPro: 2.639 ± 0.033	1.868AspGln: 1.868 ± 0.026	2.376AspArg: 2.376 ± 0.035	4.155AspSer: 4.155 ± 0.046	2.57AspThr: 2.57 ± 0.027	3.209AspVal: 3.209 ± 0.035	0.665AspTrp: 0.665 ± 0.015	1.677AspTyr: 1.677 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	4.727GluAla: 4.727 ± 0.043	1.336GluCys: 1.336 ± 0.035	4.524GluAsp: 4.524 ± 0.038	7.948GluGlu: 7.948 ± 0.092	2.287GluPhe: 2.287 ± 0.028	3.824GluGly: 3.824 ± 0.04	1.558GluHis: 1.558 ± 0.022	3.654GluIle: 3.654 ± 0.041	5.869GluLys: 5.869 ± 0.066	6.405GluLeu: 6.405 ± 0.067	1.831GluMet: 1.831 ± 0.027	3.541GluAsn: 3.541 ± 0.041	2.549GluPro: 2.549 ± 0.032	3.273GluGln: 3.273 ± 0.04	3.864GluArg: 3.864 ± 0.049	4.545GluSer: 4.545 ± 0.047	3.61GluThr: 3.61 ± 0.035	4.356GluVal: 4.356 ± 0.038	0.75GluTrp: 0.75 ± 0.016	1.871GluTyr: 1.871 ± 0.026	0.001GluXaa: 0.001 ± 0.0
Phe	2.202PheAla: 2.202 ± 0.028	1.004PheCys: 1.004 ± 0.02	1.851PheAsp: 1.851 ± 0.022	2.196PheGlu: 2.196 ± 0.029	1.863PhePhe: 1.863 ± 0.029	2.316PheGly: 2.316 ± 0.03	1.097PheHis: 1.097 ± 0.018	2.169PheIle: 2.169 ± 0.027	2.102PheLys: 2.102 ± 0.023	4.328PheLeu: 4.328 ± 0.042	0.814PheMet: 0.814 ± 0.016	1.559PheAsn: 1.559 ± 0.021	1.973PhePro: 1.973 ± 0.025	1.882PheGln: 1.882 ± 0.023	1.918PheArg: 1.918 ± 0.026	3.508PheSer: 3.508 ± 0.032	2.266PheThr: 2.266 ± 0.027	2.466PheVal: 2.466 ± 0.031	0.536PheTrp: 0.536 ± 0.013	1.369PheTyr: 1.369 ± 0.023	0.001PheXaa: 0.001 ± 0.0
Gly	3.356GlyAla: 3.356 ± 0.041	1.199GlyCys: 1.199 ± 0.023	2.903GlyAsp: 2.903 ± 0.038	3.761GlyGlu: 3.761 ± 0.049	2.504GlyPhe: 2.504 ± 0.032	3.713GlyGly: 3.713 ± 0.047	1.465GlyHis: 1.465 ± 0.023	3.113GlyIle: 3.113 ± 0.04	3.971GlyLys: 3.971 ± 0.043	5.158GlyLeu: 5.158 ± 0.047	1.341GlyMet: 1.341 ± 0.025	2.618GlyAsn: 2.618 ± 0.028	2.732GlyPro: 2.732 ± 0.089	2.463GlyGln: 2.463 ± 0.033	2.998GlyArg: 2.998 ± 0.037	4.939GlySer: 4.939 ± 0.046	3.363GlyThr: 3.363 ± 0.039	3.476GlyVal: 3.476 ± 0.035	0.748GlyTrp: 0.748 ± 0.018	1.855GlyTyr: 1.855 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	1.314HisAla: 1.314 ± 0.022	0.717HisCys: 0.717 ± 0.017	0.922HisAsp: 0.922 ± 0.018	1.371HisGlu: 1.371 ± 0.022	1.117HisPhe: 1.117 ± 0.019	1.463HisGly: 1.463 ± 0.021	0.865HisHis: 0.865 ± 0.022	1.351HisIle: 1.351 ± 0.021	1.415HisLys: 1.415 ± 0.021	2.791HisLeu: 2.791 ± 0.029	0.601HisMet: 0.601 ± 0.014	1.013HisAsn: 1.013 ± 0.017	1.456HisPro: 1.456 ± 0.024	1.191HisGln: 1.191 ± 0.017	1.429HisArg: 1.429 ± 0.023	2.198HisSer: 2.198 ± 0.034	1.292HisThr: 1.292 ± 0.019	1.52HisVal: 1.52 ± 0.02	0.343HisTrp: 0.343 ± 0.009	0.864HisTyr: 0.864 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	3.055IleAla: 3.055 ± 0.03	1.259IleCys: 1.259 ± 0.026	2.4IleAsp: 2.4 ± 0.03	2.974IleGlu: 2.974 ± 0.037	2.232IlePhe: 2.232 ± 0.032	2.552IleGly: 2.552 ± 0.032	1.409IleHis: 1.409 ± 0.021	2.845IleIle: 2.845 ± 0.039	3.131IleLys: 3.131 ± 0.036	5.078IleLeu: 5.078 ± 0.048	1.102IleMet: 1.102 ± 0.017	2.202IleAsn: 2.202 ± 0.027	2.846IlePro: 2.846 ± 0.029	2.498IleGln: 2.498 ± 0.027	2.535IleArg: 2.535 ± 0.024	4.219IleSer: 4.219 ± 0.038	2.924IleThr: 2.924 ± 0.035	2.98IleVal: 2.98 ± 0.038	0.579IleTrp: 0.579 ± 0.013	1.642IleTyr: 1.642 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	4.18LysAla: 4.18 ± 0.048	1.258LysCys: 1.258 ± 0.022	3.537LysAsp: 3.537 ± 0.033	5.8LysGlu: 5.8 ± 0.066	1.954LysPhe: 1.954 ± 0.024	3.433LysGly: 3.433 ± 0.051	1.603LysHis: 1.603 ± 0.024	3.311LysIle: 3.311 ± 0.041	5.536LysLys: 5.536 ± 0.067	5.832LysLeu: 5.832 ± 0.056	1.606LysMet: 1.606 ± 0.021	2.866LysAsn: 2.866 ± 0.032	3.093LysPro: 3.093 ± 0.036	3.073LysGln: 3.073 ± 0.035	3.575LysArg: 3.575 ± 0.038	4.292LysSer: 4.292 ± 0.042	3.528LysThr: 3.528 ± 0.039	3.821LysVal: 3.821 ± 0.035	0.702LysTrp: 0.702 ± 0.016	1.948LysTyr: 1.948 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	6.238LeuAla: 6.238 ± 0.056	2.224LeuCys: 2.224 ± 0.031	4.838LeuAsp: 4.838 ± 0.038	7.027LeuGlu: 7.027 ± 0.076	3.67LeuPhe: 3.67 ± 0.046	5.116LeuGly: 5.116 ± 0.044	2.747LeuHis: 2.747 ± 0.032	4.369LeuIle: 4.369 ± 0.043	6.53LeuLys: 6.53 ± 0.056	10.169LeuLeu: 10.169 ± 0.085	2.047LeuMet: 2.047 ± 0.025	3.977LeuAsn: 3.977 ± 0.033	5.343LeuPro: 5.343 ± 0.052	5.67LeuGln: 5.67 ± 0.061	5.106LeuArg: 5.106 ± 0.046	7.833LeuSer: 7.833 ± 0.06	5.057LeuThr: 5.057 ± 0.037	5.515LeuVal: 5.515 ± 0.05	1.087LeuTrp: 1.087 ± 0.018	2.827LeuTyr: 2.827 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	1.651MetAla: 1.651 ± 0.024	0.438MetCys: 0.438 ± 0.013	1.309MetAsp: 1.309 ± 0.018	1.862MetGlu: 1.862 ± 0.026	0.872MetPhe: 0.872 ± 0.016	1.224MetGly: 1.224 ± 0.024	0.53MetHis: 0.53 ± 0.013	0.994MetIle: 0.994 ± 0.017	1.618MetLys: 1.618 ± 0.024	2.097MetLeu: 2.097 ± 0.028	0.625MetMet: 0.625 ± 0.016	1.032MetAsn: 1.032 ± 0.017	1.033MetPro: 1.033 ± 0.021	1.045MetGln: 1.045 ± 0.019	1.057MetArg: 1.057 ± 0.018	1.583MetSer: 1.583 ± 0.022	1.17MetThr: 1.17 ± 0.017	1.469MetVal: 1.469 ± 0.02	0.271MetTrp: 0.271 ± 0.008	0.676MetTyr: 0.676 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.391AsnAla: 2.391 ± 0.029	0.999AsnCys: 0.999 ± 0.019	1.766AsnAsp: 1.766 ± 0.024	2.662AsnGlu: 2.662 ± 0.036	1.65AsnPhe: 1.65 ± 0.019	2.762AsnGly: 2.762 ± 0.037	1.021AsnHis: 1.021 ± 0.017	2.575AsnIle: 2.575 ± 0.032	2.68AsnLys: 2.68 ± 0.033	4.169AsnLeu: 4.169 ± 0.04	1.017AsnMet: 1.017 ± 0.018	1.881AsnAsn: 1.881 ± 0.028	2.276AsnPro: 2.276 ± 0.031	1.782AsnGln: 1.782 ± 0.025	2.032AsnArg: 2.032 ± 0.025	3.529AsnSer: 3.529 ± 0.039	2.279AsnThr: 2.279 ± 0.026	2.529AsnVal: 2.529 ± 0.027	0.517AsnTrp: 0.517 ± 0.013	1.335AsnTyr: 1.335 ± 0.019	0.001AsnXaa: 0.001 ± 0.0
Pro	3.665ProAla: 3.665 ± 0.045	1.021ProCys: 1.021 ± 0.02	2.597ProAsp: 2.597 ± 0.032	3.872ProGlu: 3.872 ± 0.041	1.925ProPhe: 1.925 ± 0.029	3.606ProGly: 3.606 ± 0.122	1.227ProHis: 1.227 ± 0.024	1.983ProIle: 1.983 ± 0.024	2.787ProLys: 2.787 ± 0.038	4.576ProLeu: 4.576 ± 0.042	0.946ProMet: 0.946 ± 0.021	1.926ProAsn: 1.926 ± 0.028	4.149ProPro: 4.149 ± 0.08	2.298ProGln: 2.298 ± 0.037	2.397ProArg: 2.397 ± 0.033	4.841ProSer: 4.841 ± 0.057	2.626ProThr: 2.626 ± 0.03	3.724ProVal: 3.724 ± 0.039	0.558ProTrp: 0.558 ± 0.014	1.464ProTyr: 1.464 ± 0.025	0.001ProXaa: 0.001 ± 0.001
Gln	3.026GlnAla: 3.026 ± 0.036	0.963GlnCys: 0.963 ± 0.019	2.244GlnAsp: 2.244 ± 0.024	3.75GlnGlu: 3.75 ± 0.044	1.529GlnPhe: 1.529 ± 0.022	2.42GlnGly: 2.42 ± 0.032	1.285GlnHis: 1.285 ± 0.022	2.289GlnIle: 2.289 ± 0.024	3.273GlnLys: 3.273 ± 0.037	4.668GlnLeu: 4.668 ± 0.053	1.122GlnMet: 1.122 ± 0.019	2.113GlnAsn: 2.113 ± 0.027	2.325GlnPro: 2.325 ± 0.036	3.082GlnGln: 3.082 ± 0.07	2.642GlnArg: 2.642 ± 0.03	3.26GlnSer: 3.26 ± 0.037	2.385GlnThr: 2.385 ± 0.027	2.739GlnVal: 2.739 ± 0.025	0.522GlnTrp: 0.522 ± 0.013	1.29GlnTyr: 1.29 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	2.996ArgAla: 2.996 ± 0.032	1.12ArgCys: 1.12 ± 0.021	2.529ArgAsp: 2.529 ± 0.034	3.691ArgGlu: 3.691 ± 0.042	1.895ArgPhe: 1.895 ± 0.026	2.797ArgGly: 2.797 ± 0.046	1.396ArgHis: 1.396 ± 0.023	2.593ArgIle: 2.593 ± 0.028	3.865ArgLys: 3.865 ± 0.043	4.792ArgLeu: 4.792 ± 0.044	1.167ArgMet: 1.167 ± 0.018	2.268ArgAsn: 2.268 ± 0.027	2.368ArgPro: 2.368 ± 0.032	2.473ArgGln: 2.473 ± 0.03	3.654ArgArg: 3.654 ± 0.046	3.928ArgSer: 3.928 ± 0.044	2.66ArgThr: 2.66 ± 0.027	2.862ArgVal: 2.862 ± 0.029	0.607ArgTrp: 0.607 ± 0.015	1.604ArgTyr: 1.604 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	5.162SerAla: 5.162 ± 0.048	1.83SerCys: 1.83 ± 0.027	4.046SerAsp: 4.046 ± 0.044	5.237SerGlu: 5.237 ± 0.054	3.158SerPhe: 3.158 ± 0.031	4.888SerGly: 4.888 ± 0.049	2.027SerHis: 2.027 ± 0.028	3.601SerIle: 3.601 ± 0.027	4.587SerLys: 4.587 ± 0.05	7.975SerLeu: 7.975 ± 0.062	1.62SerMet: 1.62 ± 0.021	3.146SerAsn: 3.146 ± 0.034	5.088SerPro: 5.088 ± 0.068	3.703SerGln: 3.703 ± 0.041	4.009SerArg: 4.009 ± 0.043	9.169SerSer: 9.169 ± 0.111	4.576SerThr: 4.576 ± 0.044	5.186SerVal: 5.186 ± 0.046	0.97SerTrp: 0.97 ± 0.017	2.295SerTyr: 2.295 ± 0.031	0.001SerXaa: 0.001 ± 0.0
Thr	3.854ThrAla: 3.854 ± 0.036	1.306ThrCys: 1.306 ± 0.026	2.755ThrAsp: 2.755 ± 0.03	3.839ThrGlu: 3.839 ± 0.034	2.246ThrPhe: 2.246 ± 0.029	3.376ThrGly: 3.376 ± 0.033	1.163ThrHis: 1.163 ± 0.019	2.667ThrIle: 2.667 ± 0.029	2.952ThrLys: 2.952 ± 0.03	5.178ThrLeu: 5.178 ± 0.044	1.143ThrMet: 1.143 ± 0.02	1.986ThrAsn: 1.986 ± 0.026	3.103ThrPro: 3.103 ± 0.04	2.124ThrGln: 2.124 ± 0.027	2.287ThrArg: 2.287 ± 0.024	4.701ThrSer: 4.701 ± 0.048	2.984ThrThr: 2.984 ± 0.039	4.151ThrVal: 4.151 ± 0.042	0.665ThrTrp: 0.665 ± 0.016	1.585ThrTyr: 1.585 ± 0.023	0.001ThrXaa: 0.001 ± 0.0
Val	4.065ValAla: 4.065 ± 0.037	1.511ValCys: 1.511 ± 0.025	3.081ValAsp: 3.081 ± 0.032	4.013ValGlu: 4.013 ± 0.037	2.694ValPhe: 2.694 ± 0.035	3.325ValGly: 3.325 ± 0.038	1.574ValHis: 1.574 ± 0.021	3.376ValIle: 3.376 ± 0.035	3.96ValLys: 3.96 ± 0.044	6.316ValLeu: 6.316 ± 0.053	1.414ValMet: 1.414 ± 0.021	2.624ValAsn: 2.624 ± 0.028	3.429ValPro: 3.429 ± 0.036	2.81ValGln: 2.81 ± 0.033	2.938ValArg: 2.938 ± 0.028	5.039ValSer: 5.039 ± 0.048	3.907ValThr: 3.907 ± 0.04	4.23ValVal: 4.23 ± 0.041	0.728ValTrp: 0.728 ± 0.017	1.899ValTyr: 1.899 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	0.67TrpAla: 0.67 ± 0.017	0.247TrpCys: 0.247 ± 0.008	0.675TrpAsp: 0.675 ± 0.016	0.777TrpGlu: 0.777 ± 0.016	0.473TrpPhe: 0.473 ± 0.012	0.609TrpGly: 0.609 ± 0.016	0.296TrpHis: 0.296 ± 0.01	0.662TrpIle: 0.662 ± 0.013	0.912TrpLys: 0.912 ± 0.018	1.193TrpLeu: 1.193 ± 0.023	0.318TrpMet: 0.318 ± 0.01	0.61TrpAsn: 0.61 ± 0.016	0.428TrpPro: 0.428 ± 0.012	0.552TrpGln: 0.552 ± 0.012	0.637TrpArg: 0.637 ± 0.016	0.896TrpSer: 0.896 ± 0.019	0.647TrpThr: 0.647 ± 0.014	0.666TrpVal: 0.666 ± 0.016	0.196TrpTrp: 0.196 ± 0.008	0.363TrpTyr: 0.363 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.62TyrAla: 1.62 ± 0.021	0.778TyrCys: 0.778 ± 0.016	1.499TyrAsp: 1.499 ± 0.024	1.871TyrGlu: 1.871 ± 0.026	1.444TyrPhe: 1.444 ± 0.022	1.797TyrGly: 1.797 ± 0.025	0.814TyrHis: 0.814 ± 0.015	1.68TyrIle: 1.68 ± 0.025	1.758TyrLys: 1.758 ± 0.024	3.022TyrLeu: 3.022 ± 0.032	0.691TyrMet: 0.691 ± 0.013	1.335TyrAsn: 1.335 ± 0.019	1.359TyrPro: 1.359 ± 0.024	1.337TyrGln: 1.337 ± 0.02	1.712TyrArg: 1.712 ± 0.024	2.417TyrSer: 2.417 ± 0.027	1.657TyrThr: 1.657 ± 0.022	1.765TyrVal: 1.765 ± 0.029	0.394TyrTrp: 0.394 ± 0.013	1.116TyrTyr: 1.116 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.03XaaXaa: 0.03 ± 0.006

Statistics based on 8277 proteins (3590270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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