Amino acid dipepetide frequency for Hubei virga-like virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.773AlaAla: 0.773 ± 0.362
0.387AlaCys: 0.387 ± 0.271
2.707AlaAsp: 2.707 ± 0.451
0.773AlaGlu: 0.773 ± 0.421
0.773AlaPhe: 0.773 ± 0.717
1.547AlaGly: 1.547 ± 0.545
0.773AlaHis: 0.773 ± 0.362
2.32AlaIle: 2.32 ± 0.53
1.16AlaLys: 1.16 ± 0.782
4.254AlaLeu: 4.254 ± 1.043
0.773AlaMet: 0.773 ± 0.362
3.094AlaAsn: 3.094 ± 0.7
0.387AlaPro: 0.387 ± 0.359
0.387AlaGln: 0.387 ± 0.407
0.387AlaArg: 0.387 ± 0.407
2.707AlaSer: 2.707 ± 0.671
0.773AlaThr: 0.773 ± 0.522
0.387AlaVal: 0.387 ± 0.457
0.387AlaTrp: 0.387 ± 0.407
1.933AlaTyr: 1.933 ± 1.012
0.0AlaXaa: 0.0 ± 0.0
Cys
0.773CysAla: 0.773 ± 0.362
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.387CysPhe: 0.387 ± 0.271
1.547CysGly: 1.547 ± 0.781
0.387CysHis: 0.387 ± 0.37
0.773CysIle: 0.773 ± 0.453
2.32CysLys: 2.32 ± 0.813
0.387CysLeu: 0.387 ± 0.407
0.387CysMet: 0.387 ± 0.271
1.16CysAsn: 1.16 ± 0.527
1.16CysPro: 1.16 ± 0.486
0.387CysGln: 0.387 ± 0.37
0.773CysArg: 0.773 ± 0.559
2.707CysSer: 2.707 ± 1.125
1.16CysThr: 1.16 ± 0.516
1.16CysVal: 1.16 ± 0.599
0.387CysTrp: 0.387 ± 0.407
1.16CysTyr: 1.16 ± 0.265
0.0CysXaa: 0.0 ± 0.0
Asp
1.933AspAla: 1.933 ± 0.652
0.387AspCys: 0.387 ± 0.359
5.414AspAsp: 5.414 ± 2.262
4.64AspGlu: 4.64 ± 1.006
2.32AspPhe: 2.32 ± 0.502
1.933AspGly: 1.933 ± 0.388
0.387AspHis: 0.387 ± 0.407
6.574AspIle: 6.574 ± 1.082
4.64AspLys: 4.64 ± 1.119
5.027AspLeu: 5.027 ± 1.184
2.32AspMet: 2.32 ± 0.475
5.414AspAsn: 5.414 ± 0.9
2.707AspPro: 2.707 ± 1.679
1.16AspGln: 1.16 ± 0.591
3.094AspArg: 3.094 ± 1.014
1.933AspSer: 1.933 ± 0.745
3.48AspThr: 3.48 ± 1.023
4.64AspVal: 4.64 ± 0.98
0.773AspTrp: 0.773 ± 0.618
3.867AspTyr: 3.867 ± 0.898
0.0AspXaa: 0.0 ± 0.0
Glu
0.387GluAla: 0.387 ± 0.271
1.16GluCys: 1.16 ± 0.547
3.48GluAsp: 3.48 ± 1.594
5.8GluGlu: 5.8 ± 2.018
2.707GluPhe: 2.707 ± 1.733
0.387GluGly: 0.387 ± 0.434
0.773GluHis: 0.773 ± 0.415
7.347GluIle: 7.347 ± 1.651
4.64GluLys: 4.64 ± 1.686
6.187GluLeu: 6.187 ± 2.08
0.387GluMet: 0.387 ± 0.271
5.414GluAsn: 5.414 ± 1.332
0.387GluPro: 0.387 ± 0.37
1.16GluGln: 1.16 ± 0.559
1.933GluArg: 1.933 ± 0.745
2.32GluSer: 2.32 ± 0.803
4.64GluThr: 4.64 ± 0.978
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.707GluTyr: 2.707 ± 0.892
0.0GluXaa: 0.0 ± 0.0
Phe
1.16PheAla: 1.16 ± 0.501
1.547PheCys: 1.547 ± 0.83
3.48PheAsp: 3.48 ± 0.804
4.254PheGlu: 4.254 ± 2.177
4.254PhePhe: 4.254 ± 1.063
1.16PheGly: 1.16 ± 0.265
0.0PheHis: 0.0 ± 0.0
8.121PheIle: 8.121 ± 1.927
6.574PheLys: 6.574 ± 1.096
5.027PheLeu: 5.027 ± 1.611
1.16PheMet: 1.16 ± 0.529
8.507PheAsn: 8.507 ± 2.849
1.16PhePro: 1.16 ± 0.547
1.933PheGln: 1.933 ± 0.904
2.32PheArg: 2.32 ± 0.86
3.48PheSer: 3.48 ± 0.89
3.094PheThr: 3.094 ± 1.672
3.867PheVal: 3.867 ± 0.923
1.16PheTrp: 1.16 ± 0.486
4.64PheTyr: 4.64 ± 1.475
0.0PheXaa: 0.0 ± 0.0
Gly
1.16GlyAla: 1.16 ± 0.556
1.547GlyCys: 1.547 ± 0.811
1.16GlyAsp: 1.16 ± 0.265
1.16GlyGlu: 1.16 ± 0.987
2.707GlyPhe: 2.707 ± 0.736
1.547GlyGly: 1.547 ± 1.084
1.16GlyHis: 1.16 ± 0.582
2.707GlyIle: 2.707 ± 1.114
2.707GlyLys: 2.707 ± 0.736
1.547GlyLeu: 1.547 ± 0.749
0.387GlyMet: 0.387 ± 0.271
2.707GlyAsn: 2.707 ± 1.118
0.0GlyPro: 0.0 ± 0.0
0.773GlyGln: 0.773 ± 0.559
0.773GlyArg: 0.773 ± 0.362
1.16GlySer: 1.16 ± 0.582
0.773GlyThr: 0.773 ± 0.542
0.773GlyVal: 0.773 ± 0.362
0.0GlyTrp: 0.0 ± 0.0
1.547GlyTyr: 1.547 ± 0.705
0.0GlyXaa: 0.0 ± 0.0
His
0.387HisAla: 0.387 ± 0.271
0.387HisCys: 0.387 ± 0.407
0.773HisAsp: 0.773 ± 0.814
1.933HisGlu: 1.933 ± 1.009
0.773HisPhe: 0.773 ± 0.571
0.773HisGly: 0.773 ± 0.74
0.387HisHis: 0.387 ± 0.457
0.0HisIle: 0.0 ± 0.0
1.16HisLys: 1.16 ± 0.559
1.933HisLeu: 1.933 ± 0.906
1.16HisMet: 1.16 ± 0.529
2.32HisAsn: 2.32 ± 0.695
1.16HisPro: 1.16 ± 0.951
0.773HisGln: 0.773 ± 0.559
0.0HisArg: 0.0 ± 0.0
1.547HisSer: 1.547 ± 1.287
0.773HisThr: 0.773 ± 0.453
0.387HisVal: 0.387 ± 0.271
0.387HisTrp: 0.387 ± 0.407
0.773HisTyr: 0.773 ± 0.368
0.0HisXaa: 0.0 ± 0.0
Ile
3.094IleAla: 3.094 ± 1.066
1.16IleCys: 1.16 ± 0.559
10.828IleAsp: 10.828 ± 1.805
5.414IleGlu: 5.414 ± 1.853
8.121IlePhe: 8.121 ± 3.245
1.933IleGly: 1.933 ± 0.627
1.933IleHis: 1.933 ± 0.783
13.148IleIle: 13.148 ± 2.027
8.507IleLys: 8.507 ± 1.146
13.148IleLeu: 13.148 ± 1.851
1.547IleMet: 1.547 ± 0.758
10.441IleAsn: 10.441 ± 1.007
3.867IlePro: 3.867 ± 1.729
1.933IleGln: 1.933 ± 0.962
3.48IleArg: 3.48 ± 1.191
8.894IleSer: 8.894 ± 1.747
5.8IleThr: 5.8 ± 1.349
2.707IleVal: 2.707 ± 1.081
0.773IleTrp: 0.773 ± 0.618
6.961IleTyr: 6.961 ± 1.993
0.0IleXaa: 0.0 ± 0.0
Lys
1.16LysAla: 1.16 ± 0.591
0.773LysCys: 0.773 ± 0.542
4.254LysAsp: 4.254 ± 1.348
5.027LysGlu: 5.027 ± 0.67
7.347LysPhe: 7.347 ± 1.421
0.773LysGly: 0.773 ± 0.405
2.32LysHis: 2.32 ± 0.942
11.988LysIle: 11.988 ± 1.531
8.121LysLys: 8.121 ± 3.432
11.214LysLeu: 11.214 ± 2.297
0.773LysMet: 0.773 ± 0.384
8.121LysAsn: 8.121 ± 1.356
4.64LysPro: 4.64 ± 1.322
3.48LysGln: 3.48 ± 1.001
4.64LysArg: 4.64 ± 0.703
4.64LysSer: 4.64 ± 1.084
3.867LysThr: 3.867 ± 1.515
2.32LysVal: 2.32 ± 0.915
0.0LysTrp: 0.0 ± 0.0
5.414LysTyr: 5.414 ± 0.819
0.0LysXaa: 0.0 ± 0.0
Leu
2.707LeuAla: 2.707 ± 0.81
1.16LeuCys: 1.16 ± 0.547
5.414LeuAsp: 5.414 ± 2.046
5.414LeuGlu: 5.414 ± 1.367
6.961LeuPhe: 6.961 ± 2.162
3.094LeuGly: 3.094 ± 1.545
1.547LeuHis: 1.547 ± 1.014
13.921LeuIle: 13.921 ± 2.642
8.894LeuLys: 8.894 ± 0.963
9.281LeuLeu: 9.281 ± 1.999
0.773LeuMet: 0.773 ± 0.415
9.667LeuAsn: 9.667 ± 1.726
1.933LeuPro: 1.933 ± 0.691
3.48LeuGln: 3.48 ± 1.303
1.933LeuArg: 1.933 ± 0.542
7.347LeuSer: 7.347 ± 1.087
4.64LeuThr: 4.64 ± 1.326
4.254LeuVal: 4.254 ± 1.353
0.387LeuTrp: 0.387 ± 0.457
5.414LeuTyr: 5.414 ± 0.705
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.773MetAsp: 0.773 ± 0.717
1.16MetGlu: 1.16 ± 0.813
0.773MetPhe: 0.773 ± 0.368
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.933MetIle: 1.933 ± 0.502
1.16MetLys: 1.16 ± 0.813
1.16MetLeu: 1.16 ± 0.667
0.0MetMet: 0.0 ± 0.0
1.933MetAsn: 1.933 ± 1.012
0.387MetPro: 0.387 ± 0.359
0.387MetGln: 0.387 ± 0.407
0.387MetArg: 0.387 ± 0.359
0.387MetSer: 0.387 ± 0.271
0.0MetThr: 0.0 ± 0.0
1.933MetVal: 1.933 ± 0.672
0.0MetTrp: 0.0 ± 0.0
1.547MetTyr: 1.547 ± 0.612
0.0MetXaa: 0.0 ± 0.0
Asn
3.48AsnAla: 3.48 ± 2.367
3.48AsnCys: 3.48 ± 1.437
6.961AsnAsp: 6.961 ± 1.481
4.254AsnGlu: 4.254 ± 1.841
8.894AsnPhe: 8.894 ± 2.833
2.32AsnGly: 2.32 ± 0.678
0.773AsnHis: 0.773 ± 0.415
12.761AsnIle: 12.761 ± 0.992
8.894AsnLys: 8.894 ± 1.263
11.214AsnLeu: 11.214 ± 2.263
1.547AsnMet: 1.547 ± 0.651
6.961AsnAsn: 6.961 ± 1.493
1.933AsnPro: 1.933 ± 0.341
0.773AsnGln: 0.773 ± 0.62
1.933AsnArg: 1.933 ± 1.391
5.414AsnSer: 5.414 ± 1.924
8.894AsnThr: 8.894 ± 2.256
1.547AsnVal: 1.547 ± 0.549
0.773AsnTrp: 0.773 ± 0.685
6.574AsnTyr: 6.574 ± 1.514
0.0AsnXaa: 0.0 ± 0.0
Pro
2.32ProAla: 2.32 ± 0.502
0.387ProCys: 0.387 ± 0.37
0.773ProAsp: 0.773 ± 0.415
0.0ProGlu: 0.0 ± 0.0
1.933ProPhe: 1.933 ± 0.569
0.773ProGly: 0.773 ± 0.362
0.773ProHis: 0.773 ± 0.405
1.933ProIle: 1.933 ± 0.341
1.933ProLys: 1.933 ± 1.024
2.32ProLeu: 2.32 ± 0.776
0.0ProMet: 0.0 ± 0.0
4.254ProAsn: 4.254 ± 1.429
0.387ProPro: 0.387 ± 0.407
1.16ProGln: 1.16 ± 0.435
0.387ProArg: 0.387 ± 0.271
2.32ProSer: 2.32 ± 0.542
1.933ProThr: 1.933 ± 1.046
2.32ProVal: 2.32 ± 0.913
0.0ProTrp: 0.0 ± 0.0
1.933ProTyr: 1.933 ± 0.531
0.0ProXaa: 0.0 ± 0.0
Gln
0.387GlnAla: 0.387 ± 0.359
0.387GlnCys: 0.387 ± 0.37
1.933GlnAsp: 1.933 ± 1.009
0.773GlnGlu: 0.773 ± 0.362
1.547GlnPhe: 1.547 ± 0.735
0.773GlnGly: 0.773 ± 0.362
1.547GlnHis: 1.547 ± 0.369
2.32GlnIle: 2.32 ± 0.702
1.16GlnLys: 1.16 ± 0.486
2.707GlnLeu: 2.707 ± 0.455
0.0GlnMet: 0.0 ± 0.0
3.094GlnAsn: 3.094 ± 1.089
0.773GlnPro: 0.773 ± 0.415
0.773GlnGln: 0.773 ± 0.415
1.16GlnArg: 1.16 ± 0.265
2.32GlnSer: 2.32 ± 1.232
1.547GlnThr: 1.547 ± 0.723
0.773GlnVal: 0.773 ± 0.559
0.773GlnTrp: 0.773 ± 0.496
0.773GlnTyr: 0.773 ± 0.496
0.0GlnXaa: 0.0 ± 0.0
Arg
0.773ArgAla: 0.773 ± 0.368
0.773ArgCys: 0.773 ± 0.453
3.094ArgAsp: 3.094 ± 0.839
1.16ArgGlu: 1.16 ± 0.449
3.867ArgPhe: 3.867 ± 1.482
1.547ArgGly: 1.547 ± 0.678
0.387ArgHis: 0.387 ± 0.271
4.254ArgIle: 4.254 ± 1.243
2.32ArgLys: 2.32 ± 0.79
2.707ArgLeu: 2.707 ± 0.54
0.387ArgMet: 0.387 ± 0.407
3.48ArgAsn: 3.48 ± 0.774
0.773ArgPro: 0.773 ± 0.717
1.16ArgGln: 1.16 ± 0.501
0.0ArgArg: 0.0 ± 0.0
1.547ArgSer: 1.547 ± 0.395
1.547ArgThr: 1.547 ± 0.339
1.547ArgVal: 1.547 ± 0.828
0.0ArgTrp: 0.0 ± 0.0
1.16ArgTyr: 1.16 ± 0.265
0.0ArgXaa: 0.0 ± 0.0
Ser
3.094SerAla: 3.094 ± 1.071
0.387SerCys: 0.387 ± 0.457
3.48SerAsp: 3.48 ± 0.869
2.707SerGlu: 2.707 ± 1.223
3.094SerPhe: 3.094 ± 1.141
2.707SerGly: 2.707 ± 0.967
1.933SerHis: 1.933 ± 0.878
6.961SerIle: 6.961 ± 1.476
6.961SerLys: 6.961 ± 1.564
4.254SerLeu: 4.254 ± 0.655
0.0SerMet: 0.0 ± 0.0
6.187SerAsn: 6.187 ± 2.025
1.16SerPro: 1.16 ± 0.727
0.773SerGln: 0.773 ± 0.415
2.707SerArg: 2.707 ± 0.79
5.414SerSer: 5.414 ± 2.078
4.64SerThr: 4.64 ± 0.692
3.48SerVal: 3.48 ± 1.312
0.0SerTrp: 0.0 ± 0.0
3.094SerTyr: 3.094 ± 1.695
0.0SerXaa: 0.0 ± 0.0
Thr
1.16ThrAla: 1.16 ± 0.431
1.16ThrCys: 1.16 ± 1.221
3.094ThrAsp: 3.094 ± 0.889
3.094ThrGlu: 3.094 ± 0.993
3.094ThrPhe: 3.094 ± 0.466
0.773ThrGly: 0.773 ± 0.421
1.16ThrHis: 1.16 ± 0.69
5.414ThrIle: 5.414 ± 0.819
7.347ThrLys: 7.347 ± 2.26
5.414ThrLeu: 5.414 ± 1.003
1.547ThrMet: 1.547 ± 0.758
3.48ThrAsn: 3.48 ± 1.083
2.32ThrPro: 2.32 ± 0.346
1.547ThrGln: 1.547 ± 0.508
3.48ThrArg: 3.48 ± 0.652
3.48ThrSer: 3.48 ± 0.883
6.574ThrThr: 6.574 ± 1.968
2.707ThrVal: 2.707 ± 1.027
1.16ThrTrp: 1.16 ± 0.901
3.094ThrTyr: 3.094 ± 0.737
0.0ThrXaa: 0.0 ± 0.0
Val
1.933ValAla: 1.933 ± 0.69
1.16ValCys: 1.16 ± 0.526
1.547ValAsp: 1.547 ± 0.508
3.867ValGlu: 3.867 ± 1.03
2.707ValPhe: 2.707 ± 0.554
0.387ValGly: 0.387 ± 0.407
0.773ValHis: 0.773 ± 0.368
5.027ValIle: 5.027 ± 0.827
4.254ValLys: 4.254 ± 1.874
4.64ValLeu: 4.64 ± 0.899
0.0ValMet: 0.0 ± 0.0
4.254ValAsn: 4.254 ± 1.139
1.933ValPro: 1.933 ± 0.843
0.773ValGln: 0.773 ± 0.511
0.773ValArg: 0.773 ± 0.542
1.933ValSer: 1.933 ± 0.341
1.547ValThr: 1.547 ± 0.339
1.547ValVal: 1.547 ± 0.503
0.0ValTrp: 0.0 ± 0.0
0.387ValTyr: 0.387 ± 0.407
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.773TrpPhe: 0.773 ± 0.62
0.773TrpGly: 0.773 ± 0.814
0.0TrpHis: 0.0 ± 0.0
0.773TrpIle: 0.773 ± 0.869
1.16TrpLys: 1.16 ± 0.527
1.547TrpLeu: 1.547 ± 0.715
0.0TrpMet: 0.0 ± 0.0
0.773TrpAsn: 0.773 ± 0.62
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.773TrpVal: 0.773 ± 0.62
0.0TrpTrp: 0.0 ± 0.0
0.773TrpTyr: 0.773 ± 0.496
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.773TyrCys: 0.773 ± 0.605
3.867TyrAsp: 3.867 ± 0.699
0.387TyrGlu: 0.387 ± 0.271
3.867TyrPhe: 3.867 ± 1.648
1.547TyrGly: 1.547 ± 0.799
0.773TyrHis: 0.773 ± 0.415
5.414TyrIle: 5.414 ± 1.38
6.961TyrLys: 6.961 ± 1.154
4.254TyrLeu: 4.254 ± 1.107
0.387TyrMet: 0.387 ± 0.359
8.121TyrAsn: 8.121 ± 0.692
0.773TyrPro: 0.773 ± 0.559
2.707TyrGln: 2.707 ± 0.79
2.32TyrArg: 2.32 ± 0.965
3.48TyrSer: 3.48 ± 0.804
5.414TyrThr: 5.414 ± 1.792
2.32TyrVal: 2.32 ± 1.111
0.387TyrTrp: 0.387 ± 0.407
4.254TyrTyr: 4.254 ± 0.932
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2587 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski