Amino acid dipepetide frequency for Leek white stripe virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.481AlaAla: 4.481 ± 1.337
1.494AlaCys: 1.494 ± 1.718
0.747AlaAsp: 0.747 ± 0.417
2.24AlaGlu: 2.24 ± 0.934
3.734AlaPhe: 3.734 ± 0.742
2.24AlaGly: 2.24 ± 1.251
0.0AlaHis: 0.0 ± 0.0
1.494AlaIle: 1.494 ± 1.56
3.734AlaLys: 3.734 ± 1.715
5.975AlaLeu: 5.975 ± 1.219
2.24AlaMet: 2.24 ± 0.924
4.481AlaAsn: 4.481 ± 0.956
3.734AlaPro: 3.734 ± 1.076
1.494AlaGln: 1.494 ± 1.238
8.215AlaArg: 8.215 ± 2.975
4.481AlaSer: 4.481 ± 1.505
4.481AlaThr: 4.481 ± 1.768
8.962AlaVal: 8.962 ± 3.453
1.494AlaTrp: 1.494 ± 0.834
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.747CysAla: 0.747 ± 0.417
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
3.734CysPhe: 3.734 ± 2.431
0.0CysGly: 0.0 ± 0.0
2.987CysHis: 2.987 ± 1.656
1.494CysIle: 1.494 ± 0.828
0.747CysLys: 0.747 ± 0.78
0.0CysLeu: 0.0 ± 0.0
0.747CysMet: 0.747 ± 0.417
2.24CysAsn: 2.24 ± 0.78
0.747CysPro: 0.747 ± 0.417
0.747CysGln: 0.747 ± 0.417
2.24CysArg: 2.24 ± 0.934
2.987CysSer: 2.987 ± 1.227
0.747CysThr: 0.747 ± 0.417
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.747CysTyr: 0.747 ± 1.429
0.0CysXaa: 0.0 ± 0.0
Asp
2.24AspAla: 2.24 ± 0.726
2.24AspCys: 2.24 ± 0.934
2.987AspAsp: 2.987 ± 1.161
3.734AspGlu: 3.734 ± 1.715
2.24AspPhe: 2.24 ± 1.358
2.987AspGly: 2.987 ± 1.667
1.494AspHis: 1.494 ± 1.055
1.494AspIle: 1.494 ± 0.828
1.494AspLys: 1.494 ± 1.718
3.734AspLeu: 3.734 ± 1.513
2.987AspMet: 2.987 ± 1.186
1.494AspAsn: 1.494 ± 0.628
2.987AspPro: 2.987 ± 1.003
1.494AspGln: 1.494 ± 0.628
0.747AspArg: 0.747 ± 0.78
5.228AspSer: 5.228 ± 1.145
0.0AspThr: 0.0 ± 0.0
2.24AspVal: 2.24 ± 0.934
0.0AspTrp: 0.0 ± 0.0
1.494AspTyr: 1.494 ± 0.628
0.0AspXaa: 0.0 ± 0.0
Glu
3.734GluAla: 3.734 ± 1.513
0.0GluCys: 0.0 ± 0.0
2.987GluAsp: 2.987 ± 1.14
5.228GluGlu: 5.228 ± 2.257
3.734GluPhe: 3.734 ± 1.69
4.481GluGly: 4.481 ± 3.964
1.494GluHis: 1.494 ± 0.834
0.747GluIle: 0.747 ± 0.417
2.987GluLys: 2.987 ± 1.249
2.987GluLeu: 2.987 ± 0.637
4.481GluMet: 4.481 ± 1.868
2.24GluAsn: 2.24 ± 1.358
3.734GluPro: 3.734 ± 1.088
1.494GluGln: 1.494 ± 0.628
3.734GluArg: 3.734 ± 1.447
3.734GluSer: 3.734 ± 1.228
3.734GluThr: 3.734 ± 0.991
0.747GluVal: 0.747 ± 0.417
0.0GluTrp: 0.0 ± 0.0
0.747GluTyr: 0.747 ± 0.417
0.0GluXaa: 0.0 ± 0.0
Phe
0.747PheAla: 0.747 ± 0.78
1.494PheCys: 1.494 ± 1.238
2.24PheAsp: 2.24 ± 1.353
0.747PheGlu: 0.747 ± 0.417
5.228PhePhe: 5.228 ± 2.172
4.481PheGly: 4.481 ± 1.875
1.494PheHis: 1.494 ± 0.828
5.975PheIle: 5.975 ± 2.38
2.987PheLys: 2.987 ± 1.161
5.975PheLeu: 5.975 ± 2.323
3.734PheMet: 3.734 ± 1.067
3.734PheAsn: 3.734 ± 2.449
2.987PhePro: 2.987 ± 1.136
2.987PheGln: 2.987 ± 1.186
1.494PheArg: 1.494 ± 0.834
5.975PheSer: 5.975 ± 1.566
4.481PheThr: 4.481 ± 1.204
8.962PheVal: 8.962 ± 2.31
0.747PheTrp: 0.747 ± 0.417
1.494PheTyr: 1.494 ± 0.834
0.0PheXaa: 0.0 ± 0.0
Gly
5.228GlyAla: 5.228 ± 2.069
0.747GlyCys: 0.747 ± 0.417
4.481GlyAsp: 4.481 ± 2.254
2.24GlyGlu: 2.24 ± 1.251
5.228GlyPhe: 5.228 ± 2.257
4.481GlyGly: 4.481 ± 1.883
0.747GlyHis: 0.747 ± 1.429
2.987GlyIle: 2.987 ± 1.003
2.987GlyLys: 2.987 ± 1.752
7.468GlyLeu: 7.468 ± 2.548
0.747GlyMet: 0.747 ± 0.417
3.734GlyAsn: 3.734 ± 0.742
2.987GlyPro: 2.987 ± 1.161
1.494GlyGln: 1.494 ± 1.56
3.734GlyArg: 3.734 ± 2.084
5.228GlySer: 5.228 ± 1.896
3.734GlyThr: 3.734 ± 1.096
5.228GlyVal: 5.228 ± 1.373
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.24HisAla: 2.24 ± 0.78
1.494HisCys: 1.494 ± 0.828
0.747HisAsp: 0.747 ± 0.417
1.494HisGlu: 1.494 ± 1.238
0.747HisPhe: 0.747 ± 0.417
2.24HisGly: 2.24 ± 0.934
0.747HisHis: 0.747 ± 1.125
4.481HisIle: 4.481 ± 1.868
2.24HisLys: 2.24 ± 1.854
0.747HisLeu: 0.747 ± 0.417
0.0HisMet: 0.0 ± 0.0
1.494HisAsn: 1.494 ± 0.834
0.0HisPro: 0.0 ± 0.0
1.494HisGln: 1.494 ± 0.834
2.987HisArg: 2.987 ± 1.656
2.24HisSer: 2.24 ± 0.726
3.734HisThr: 3.734 ± 1.406
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.494HisTyr: 1.494 ± 0.828
0.0HisXaa: 0.0 ± 0.0
Ile
7.468IleAla: 7.468 ± 1.745
0.747IleCys: 0.747 ± 0.417
1.494IleAsp: 1.494 ± 0.628
1.494IleGlu: 1.494 ± 1.56
2.24IlePhe: 2.24 ± 1.353
2.987IleGly: 2.987 ± 2.11
0.0IleHis: 0.0 ± 0.0
2.987IleIle: 2.987 ± 2.758
0.0IleLys: 0.0 ± 0.0
2.24IleLeu: 2.24 ± 0.934
2.987IleMet: 2.987 ± 1.161
3.734IleAsn: 3.734 ± 2.161
3.734IlePro: 3.734 ± 2.026
1.494IleGln: 1.494 ± 0.628
2.987IleArg: 2.987 ± 1.186
2.987IleSer: 2.987 ± 1.249
2.24IleThr: 2.24 ± 0.934
5.228IleVal: 5.228 ± 3.118
1.494IleTrp: 1.494 ± 0.628
1.494IleTyr: 1.494 ± 1.56
0.0IleXaa: 0.0 ± 0.0
Lys
1.494LysAla: 1.494 ± 0.834
0.0LysCys: 0.0 ± 0.0
2.987LysAsp: 2.987 ± 1.186
4.481LysGlu: 4.481 ± 2.254
0.747LysPhe: 0.747 ± 0.417
2.987LysGly: 2.987 ± 1.003
2.987LysHis: 2.987 ± 1.186
0.747LysIle: 0.747 ± 0.417
0.747LysLys: 0.747 ± 0.78
4.481LysLeu: 4.481 ± 1.022
2.24LysMet: 2.24 ± 1.351
0.747LysAsn: 0.747 ± 0.78
3.734LysPro: 3.734 ± 1.202
0.747LysGln: 0.747 ± 0.417
2.987LysArg: 2.987 ± 1.161
6.721LysSer: 6.721 ± 1.492
4.481LysThr: 4.481 ± 1.651
4.481LysVal: 4.481 ± 0.805
0.0LysTrp: 0.0 ± 0.0
2.987LysTyr: 2.987 ± 2.118
0.747LysXaa: 0.747 ± 0.417
Leu
6.721LeuAla: 6.721 ± 1.104
2.24LeuCys: 2.24 ± 1.358
0.747LeuAsp: 0.747 ± 0.417
7.468LeuGlu: 7.468 ± 1.838
8.215LeuPhe: 8.215 ± 2.607
8.962LeuGly: 8.962 ± 1.594
2.24LeuHis: 2.24 ± 1.251
1.494LeuIle: 1.494 ± 0.834
1.494LeuLys: 1.494 ± 0.834
8.962LeuLeu: 8.962 ± 2.136
1.494LeuMet: 1.494 ± 0.828
2.24LeuAsn: 2.24 ± 0.726
4.481LeuPro: 4.481 ± 0.805
5.228LeuGln: 5.228 ± 0.985
0.747LeuArg: 0.747 ± 0.417
5.975LeuSer: 5.975 ± 1.458
2.987LeuThr: 2.987 ± 1.667
5.975LeuVal: 5.975 ± 1.91
0.0LeuTrp: 0.0 ± 0.0
2.987LeuTyr: 2.987 ± 0.637
0.0LeuXaa: 0.0 ± 0.0
Met
2.987MetAla: 2.987 ± 1.656
0.747MetCys: 0.747 ± 0.417
2.24MetAsp: 2.24 ± 0.934
1.494MetGlu: 1.494 ± 1.238
2.987MetPhe: 2.987 ± 0.637
1.494MetGly: 1.494 ± 0.828
4.481MetHis: 4.481 ± 1.337
0.747MetIle: 0.747 ± 0.417
1.494MetLys: 1.494 ± 0.834
0.0MetLeu: 0.0 ± 0.0
1.494MetMet: 1.494 ± 0.794
0.747MetAsn: 0.747 ± 0.417
0.747MetPro: 0.747 ± 0.417
0.0MetGln: 0.0 ± 0.0
2.987MetArg: 2.987 ± 1.656
2.24MetSer: 2.24 ± 2.642
2.24MetThr: 2.24 ± 2.254
5.975MetVal: 5.975 ± 1.298
0.747MetTrp: 0.747 ± 0.417
0.747MetTyr: 0.747 ± 1.429
0.0MetXaa: 0.0 ± 0.0
Asn
1.494AsnAla: 1.494 ± 0.628
1.494AsnCys: 1.494 ± 0.628
1.494AsnAsp: 1.494 ± 0.834
2.987AsnGlu: 2.987 ± 1.14
4.481AsnPhe: 4.481 ± 4.508
2.24AsnGly: 2.24 ± 0.726
1.494AsnHis: 1.494 ± 0.828
2.987AsnIle: 2.987 ± 1.136
1.494AsnLys: 1.494 ± 1.56
5.228AsnLeu: 5.228 ± 0.677
0.747AsnMet: 0.747 ± 0.78
3.734AsnAsn: 3.734 ± 2.891
1.494AsnPro: 1.494 ± 1.56
1.494AsnGln: 1.494 ± 1.055
2.987AsnArg: 2.987 ± 2.118
1.494AsnSer: 1.494 ± 0.828
0.747AsnThr: 0.747 ± 0.417
5.228AsnVal: 5.228 ± 1.579
0.747AsnTrp: 0.747 ± 0.417
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.734ProAla: 3.734 ± 1.96
0.747ProCys: 0.747 ± 0.417
1.494ProAsp: 1.494 ± 0.834
4.481ProGlu: 4.481 ± 1.69
2.24ProPhe: 2.24 ± 1.434
3.734ProGly: 3.734 ± 1.076
0.0ProHis: 0.0 ± 0.0
4.481ProIle: 4.481 ± 0.956
3.734ProLys: 3.734 ± 0.742
5.228ProLeu: 5.228 ± 2.667
2.987ProMet: 2.987 ± 1.82
1.494ProAsn: 1.494 ± 1.56
2.24ProPro: 2.24 ± 1.218
1.494ProGln: 1.494 ± 0.828
2.987ProArg: 2.987 ± 1.667
2.987ProSer: 2.987 ± 1.322
2.987ProThr: 2.987 ± 1.003
5.975ProVal: 5.975 ± 1.616
0.0ProTrp: 0.0 ± 0.0
0.747ProTyr: 0.747 ± 0.78
0.0ProXaa: 0.0 ± 0.0
Gln
0.747GlnAla: 0.747 ± 0.417
1.494GlnCys: 1.494 ± 0.828
0.0GlnAsp: 0.0 ± 0.0
0.747GlnGlu: 0.747 ± 0.417
1.494GlnPhe: 1.494 ± 0.834
1.494GlnGly: 1.494 ± 0.628
1.494GlnHis: 1.494 ± 0.834
0.747GlnIle: 0.747 ± 0.417
0.0GlnLys: 0.0 ± 0.0
4.481GlnLeu: 4.481 ± 1.022
1.494GlnMet: 1.494 ± 1.56
2.24GlnAsn: 2.24 ± 1.434
1.494GlnPro: 1.494 ± 0.834
0.0GlnGln: 0.0 ± 0.0
2.24GlnArg: 2.24 ± 0.934
0.747GlnSer: 0.747 ± 0.78
2.24GlnThr: 2.24 ± 1.218
3.734GlnVal: 3.734 ± 1.984
0.0GlnTrp: 0.0 ± 0.0
1.494GlnTyr: 1.494 ± 1.422
0.0GlnXaa: 0.0 ± 0.0
Arg
2.987ArgAla: 2.987 ± 1.186
0.747ArgCys: 0.747 ± 0.417
2.987ArgAsp: 2.987 ± 0.637
2.24ArgGlu: 2.24 ± 1.199
8.962ArgPhe: 8.962 ± 3.736
3.734ArgGly: 3.734 ± 1.354
1.494ArgHis: 1.494 ± 0.628
0.747ArgIle: 0.747 ± 0.417
6.721ArgLys: 6.721 ± 1.818
6.721ArgLeu: 6.721 ± 2.686
3.734ArgMet: 3.734 ± 0.742
2.987ArgAsn: 2.987 ± 0.637
2.987ArgPro: 2.987 ± 1.161
0.747ArgGln: 0.747 ± 0.78
6.721ArgArg: 6.721 ± 1.067
4.481ArgSer: 4.481 ± 4.152
3.734ArgThr: 3.734 ± 1.715
2.987ArgVal: 2.987 ± 1.667
0.0ArgTrp: 0.0 ± 0.0
3.734ArgTyr: 3.734 ± 2.084
0.0ArgXaa: 0.0 ± 0.0
Ser
4.481SerAla: 4.481 ± 1.496
2.24SerCys: 2.24 ± 1.358
1.494SerAsp: 1.494 ± 1.718
2.987SerGlu: 2.987 ± 2.793
5.228SerPhe: 5.228 ± 2.36
4.481SerGly: 4.481 ± 1.451
3.734SerHis: 3.734 ± 1.406
2.24SerIle: 2.24 ± 1.353
5.228SerLys: 5.228 ± 4.204
4.481SerLeu: 4.481 ± 1.204
1.494SerMet: 1.494 ± 1.238
2.24SerAsn: 2.24 ± 2.341
2.987SerPro: 2.987 ± 1.161
2.987SerGln: 2.987 ± 0.637
11.202SerArg: 11.202 ± 2.937
3.734SerSer: 3.734 ± 4.51
2.24SerThr: 2.24 ± 1.353
2.987SerVal: 2.987 ± 1.255
1.494SerTrp: 1.494 ± 0.628
1.494SerTyr: 1.494 ± 0.834
0.0SerXaa: 0.0 ± 0.0
Thr
5.228ThrAla: 5.228 ± 1.549
1.494ThrCys: 1.494 ± 0.828
3.734ThrAsp: 3.734 ± 0.742
2.24ThrGlu: 2.24 ± 0.78
1.494ThrPhe: 1.494 ± 0.628
2.987ThrGly: 2.987 ± 1.003
2.24ThrHis: 2.24 ± 0.934
2.24ThrIle: 2.24 ± 1.218
2.24ThrLys: 2.24 ± 1.251
0.747ThrLeu: 0.747 ± 0.78
1.494ThrMet: 1.494 ± 0.628
0.747ThrAsn: 0.747 ± 0.78
6.721ThrPro: 6.721 ± 1.104
2.24ThrGln: 2.24 ± 2.309
3.734ThrArg: 3.734 ± 1.447
3.734ThrSer: 3.734 ± 1.076
8.215ThrThr: 8.215 ± 0.596
2.24ThrVal: 2.24 ± 1.172
0.747ThrTrp: 0.747 ± 0.417
1.494ThrTyr: 1.494 ± 0.828
0.0ThrXaa: 0.0 ± 0.0
Val
6.721ValAla: 6.721 ± 2.634
0.0ValCys: 0.0 ± 0.0
8.962ValAsp: 8.962 ± 2.076
6.721ValGlu: 6.721 ± 1.993
2.987ValPhe: 2.987 ± 1.361
5.228ValGly: 5.228 ± 1.145
1.494ValHis: 1.494 ± 1.238
8.215ValIle: 8.215 ± 3.915
6.721ValLys: 6.721 ± 2.802
7.468ValLeu: 7.468 ± 1.473
1.494ValMet: 1.494 ± 0.828
2.24ValAsn: 2.24 ± 2.341
5.228ValPro: 5.228 ± 2.526
0.0ValGln: 0.0 ± 0.0
2.987ValArg: 2.987 ± 1.14
2.24ValSer: 2.24 ± 0.726
0.0ValThr: 0.0 ± 0.0
3.734ValVal: 3.734 ± 2.449
1.494ValTrp: 1.494 ± 1.055
3.734ValTyr: 3.734 ± 1.406
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.747TrpCys: 0.747 ± 0.417
0.747TrpAsp: 0.747 ± 0.417
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.747TrpGly: 0.747 ± 0.78
0.0TrpHis: 0.0 ± 0.0
0.747TrpIle: 0.747 ± 1.125
1.494TrpLys: 1.494 ± 0.628
2.24TrpLeu: 2.24 ± 1.251
0.0TrpMet: 0.0 ± 0.0
0.747TrpAsn: 0.747 ± 0.417
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.747TrpArg: 0.747 ± 0.417
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.747TrpVal: 0.747 ± 0.417
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.24TyrAla: 2.24 ± 0.78
0.747TyrCys: 0.747 ± 0.78
0.747TyrAsp: 0.747 ± 0.78
0.0TyrGlu: 0.0 ± 0.0
2.24TyrPhe: 2.24 ± 1.358
0.747TyrGly: 0.747 ± 0.417
0.0TyrHis: 0.0 ± 0.0
2.987TyrIle: 2.987 ± 1.229
2.987TyrLys: 2.987 ± 1.003
1.494TyrLeu: 1.494 ± 0.628
0.0TyrMet: 0.0 ± 0.0
0.747TyrAsn: 0.747 ± 0.417
0.747TyrPro: 0.747 ± 0.78
0.747TyrGln: 0.747 ± 0.417
2.987TyrArg: 2.987 ± 1.227
2.24TyrSer: 2.24 ± 0.78
2.987TyrThr: 2.987 ± 1.667
2.24TyrVal: 2.24 ± 0.78
0.0TyrTrp: 0.0 ± 0.0
0.747TyrTyr: 0.747 ± 0.417
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.747XaaGly: 0.747 ± 0.417
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1340 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski