Amino acid dipepetide frequency for Tetrabaena socialis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	37.869AlaAla: 37.869 ± 0.291	2.342AlaCys: 2.342 ± 0.029	5.999AlaAsp: 5.999 ± 0.039	7.784AlaGlu: 7.784 ± 0.068	3.005AlaPhe: 3.005 ± 0.03	14.964AlaGly: 14.964 ± 0.093	2.502AlaHis: 2.502 ± 0.025	2.763AlaIle: 2.763 ± 0.027	3.349AlaLys: 3.349 ± 0.037	12.443AlaLeu: 12.443 ± 0.086	2.557AlaMet: 2.557 ± 0.022	2.38AlaAsn: 2.38 ± 0.025	9.82AlaPro: 9.82 ± 0.085	4.97AlaGln: 4.97 ± 0.046	8.482AlaArg: 8.482 ± 0.065	10.267AlaSer: 10.267 ± 0.065	6.663AlaThr: 6.663 ± 0.046	10.008AlaVal: 10.008 ± 0.052	1.753AlaTrp: 1.753 ± 0.02	1.99AlaTyr: 1.99 ± 0.021	0.006AlaXaa: 0.006 ± 0.001
Cys	2.032CysAla: 2.032 ± 0.025	0.622CysCys: 0.622 ± 0.015	0.785CysAsp: 0.785 ± 0.015	0.713CysGlu: 0.713 ± 0.013	0.493CysPhe: 0.493 ± 0.01	1.802CysGly: 1.802 ± 0.022	0.342CysHis: 0.342 ± 0.008	0.518CysIle: 0.518 ± 0.011	0.524CysLys: 0.524 ± 0.014	1.602CysLeu: 1.602 ± 0.019	0.381CysMet: 0.381 ± 0.009	0.449CysAsn: 0.449 ± 0.01	1.162CysPro: 1.162 ± 0.024	0.51CysGln: 0.51 ± 0.009	1.236CysArg: 1.236 ± 0.018	1.458CysSer: 1.458 ± 0.019	0.976CysThr: 0.976 ± 0.017	1.121CysVal: 1.121 ± 0.016	0.319CysTrp: 0.319 ± 0.009	0.334CysTyr: 0.334 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.12AspAla: 6.12 ± 0.041	0.714AspCys: 0.714 ± 0.012	2.724AspAsp: 2.724 ± 0.03	2.843AspGlu: 2.843 ± 0.03	1.321AspPhe: 1.321 ± 0.019	5.043AspGly: 5.043 ± 0.041	0.758AspHis: 0.758 ± 0.014	1.43AspIle: 1.43 ± 0.022	1.417AspLys: 1.417 ± 0.028	3.977AspLeu: 3.977 ± 0.031	0.983AspMet: 0.983 ± 0.014	0.996AspAsn: 0.996 ± 0.016	2.889AspPro: 2.889 ± 0.025	1.135AspGln: 1.135 ± 0.016	2.445AspArg: 2.445 ± 0.031	2.798AspSer: 2.798 ± 0.025	2.068AspThr: 2.068 ± 0.023	3.465AspVal: 3.465 ± 0.031	0.749AspTrp: 0.749 ± 0.015	0.893AspTyr: 0.893 ± 0.015	0.001AspXaa: 0.001 ± 0.0
Glu	8.481GluAla: 8.481 ± 0.067	0.675GluCys: 0.675 ± 0.012	2.632GluAsp: 2.632 ± 0.028	4.536GluGlu: 4.536 ± 0.053	1.077GluPhe: 1.077 ± 0.015	5.01GluGly: 5.01 ± 0.04	1.066GluHis: 1.066 ± 0.015	1.015GluIle: 1.015 ± 0.017	1.376GluLys: 1.376 ± 0.024	5.587GluLeu: 5.587 ± 0.048	0.971GluMet: 0.971 ± 0.014	0.775GluAsn: 0.775 ± 0.013	2.724GluPro: 2.724 ± 0.031	2.602GluGln: 2.602 ± 0.031	3.729GluArg: 3.729 ± 0.036	2.223GluSer: 2.223 ± 0.021	1.593GluThr: 1.593 ± 0.02	3.913GluVal: 3.913 ± 0.029	0.808GluTrp: 0.808 ± 0.018	0.964GluTyr: 0.964 ± 0.014	0.002GluXaa: 0.002 ± 0.001
Phe	2.688PheAla: 2.688 ± 0.022	0.49PheCys: 0.49 ± 0.011	1.312PheAsp: 1.312 ± 0.02	1.216PheGlu: 1.216 ± 0.015	0.861PhePhe: 0.861 ± 0.015	2.174PheGly: 2.174 ± 0.026	0.485PheHis: 0.485 ± 0.009	0.8PheIle: 0.8 ± 0.015	0.949PheLys: 0.949 ± 0.015	2.201PheLeu: 2.201 ± 0.024	0.573PheMet: 0.573 ± 0.01	0.805PheAsn: 0.805 ± 0.013	1.198PhePro: 1.198 ± 0.018	0.796PheGln: 0.796 ± 0.015	1.474PheArg: 1.474 ± 0.017	1.841PheSer: 1.841 ± 0.018	1.385PheThr: 1.385 ± 0.021	1.749PheVal: 1.749 ± 0.02	0.359PheTrp: 0.359 ± 0.009	0.603PheTyr: 0.603 ± 0.011	0.001PheXaa: 0.001 ± 0.0
Gly	14.097GlyAla: 14.097 ± 0.089	2.035GlyCys: 2.035 ± 0.031	4.236GlyAsp: 4.236 ± 0.035	4.456GlyGlu: 4.456 ± 0.034	2.052GlyPhe: 2.052 ± 0.022	19.255GlyGly: 19.255 ± 0.191	1.968GlyHis: 1.968 ± 0.026	2.01GlyIle: 2.01 ± 0.026	2.434GlyLys: 2.434 ± 0.027	7.581GlyLeu: 7.581 ± 0.046	1.916GlyMet: 1.916 ± 0.023	1.933GlyAsn: 1.933 ± 0.024	6.153GlyPro: 6.153 ± 0.053	3.266GlyGln: 3.266 ± 0.034	6.921GlyArg: 6.921 ± 0.054	8.518GlySer: 8.518 ± 0.066	4.219GlyThr: 4.219 ± 0.037	5.784GlyVal: 5.784 ± 0.033	1.38GlyTrp: 1.38 ± 0.017	1.65GlyTyr: 1.65 ± 0.022	0.006GlyXaa: 0.006 ± 0.001
His	2.741HisAla: 2.741 ± 0.027	0.385HisCys: 0.385 ± 0.009	0.897HisAsp: 0.897 ± 0.016	0.986HisGlu: 0.986 ± 0.018	0.602HisPhe: 0.602 ± 0.011	2.026HisGly: 2.026 ± 0.025	0.965HisHis: 0.965 ± 0.025	0.652HisIle: 0.652 ± 0.011	0.616HisLys: 0.616 ± 0.012	2.161HisLeu: 2.161 ± 0.022	0.521HisMet: 0.521 ± 0.01	0.517HisAsn: 0.517 ± 0.01	1.652HisPro: 1.652 ± 0.022	1.09HisGln: 1.09 ± 0.023	1.522HisArg: 1.522 ± 0.017	1.438HisSer: 1.438 ± 0.018	1.128HisThr: 1.128 ± 0.017	1.537HisVal: 1.537 ± 0.02	0.329HisTrp: 0.329 ± 0.008	0.444HisTyr: 0.444 ± 0.01	0.001HisXaa: 0.001 ± 0.001
Ile	2.749IleAla: 2.749 ± 0.028	0.428IleCys: 0.428 ± 0.01	1.254IleAsp: 1.254 ± 0.02	1.208IleGlu: 1.208 ± 0.016	0.777IlePhe: 0.777 ± 0.015	1.726IleGly: 1.726 ± 0.024	0.54IleHis: 0.54 ± 0.012	1.023IleIle: 1.023 ± 0.025	1.075IleLys: 1.075 ± 0.018	2.071IleLeu: 2.071 ± 0.023	0.601IleMet: 0.601 ± 0.013	0.852IleAsn: 0.852 ± 0.015	1.266IlePro: 1.266 ± 0.018	0.812IleGln: 0.812 ± 0.014	1.53IleArg: 1.53 ± 0.021	1.73IleSer: 1.73 ± 0.021	1.506IleThr: 1.506 ± 0.018	1.766IleVal: 1.766 ± 0.021	0.306IleTrp: 0.306 ± 0.007	0.557IleTyr: 0.557 ± 0.011	0.001IleXaa: 0.001 ± 0.0
Lys	3.484LysAla: 3.484 ± 0.048	0.362LysCys: 0.362 ± 0.01	1.398LysAsp: 1.398 ± 0.021	1.873LysGlu: 1.873 ± 0.033	0.709LysPhe: 0.709 ± 0.014	2.199LysGly: 2.199 ± 0.027	0.617LysHis: 0.617 ± 0.012	0.76LysIle: 0.76 ± 0.013	1.48LysLys: 1.48 ± 0.03	2.683LysLeu: 2.683 ± 0.026	0.625LysMet: 0.625 ± 0.013	0.654LysAsn: 0.654 ± 0.013	1.66LysPro: 1.66 ± 0.024	1.269LysGln: 1.269 ± 0.02	2.028LysArg: 2.028 ± 0.026	1.492LysSer: 1.492 ± 0.021	1.233LysThr: 1.233 ± 0.018	1.962LysVal: 1.962 ± 0.023	0.341LysTrp: 0.341 ± 0.009	0.702LysTyr: 0.702 ± 0.014	0.001LysXaa: 0.001 ± 0.0
Leu	12.836LeuAla: 12.836 ± 0.093	1.602LeuCys: 1.602 ± 0.021	4.291LeuAsp: 4.291 ± 0.033	5.197LeuGlu: 5.197 ± 0.042	2.253LeuPhe: 2.253 ± 0.023	7.303LeuGly: 7.303 ± 0.045	2.538LeuHis: 2.538 ± 0.025	1.974LeuIle: 1.974 ± 0.02	2.655LeuLys: 2.655 ± 0.031	12.276LeuLeu: 12.276 ± 0.097	1.866LeuMet: 1.866 ± 0.022	1.857LeuAsn: 1.857 ± 0.02	7.357LeuPro: 7.357 ± 0.05	5.025LeuGln: 5.025 ± 0.045	7.8LeuArg: 7.8 ± 0.05	6.229LeuSer: 6.229 ± 0.038	4.236LeuThr: 4.236 ± 0.033	6.251LeuVal: 6.251 ± 0.039	1.251LeuTrp: 1.251 ± 0.02	1.968LeuTyr: 1.968 ± 0.022	0.003LeuXaa: 0.003 ± 0.001
Met	2.685MetAla: 2.685 ± 0.025	0.312MetCys: 0.312 ± 0.008	0.988MetAsp: 0.988 ± 0.014	1.149MetGlu: 1.149 ± 0.016	0.482MetPhe: 0.482 ± 0.009	1.667MetGly: 1.667 ± 0.024	0.468MetHis: 0.468 ± 0.009	0.441MetIle: 0.441 ± 0.011	0.516MetLys: 0.516 ± 0.012	2.134MetLeu: 2.134 ± 0.02	0.524MetMet: 0.524 ± 0.012	0.39MetAsn: 0.39 ± 0.01	1.35MetPro: 1.35 ± 0.017	1.005MetGln: 1.005 ± 0.015	1.479MetArg: 1.479 ± 0.017	1.309MetSer: 1.309 ± 0.019	0.892MetThr: 0.892 ± 0.013	1.27MetVal: 1.27 ± 0.016	0.264MetTrp: 0.264 ± 0.008	0.467MetTyr: 0.467 ± 0.01	0.001MetXaa: 0.001 ± 0.0
Asn	2.273AsnAla: 2.273 ± 0.031	0.359AsnCys: 0.359 ± 0.01	0.962AsnAsp: 0.962 ± 0.014	0.939AsnGlu: 0.939 ± 0.013	0.648AsnPhe: 0.648 ± 0.014	2.175AsnGly: 2.175 ± 0.025	0.449AsnHis: 0.449 ± 0.01	0.861AsnIle: 0.861 ± 0.017	0.819AsnLys: 0.819 ± 0.016	1.905AsnLeu: 1.905 ± 0.022	0.531AsnMet: 0.531 ± 0.01	0.682AsnAsn: 0.682 ± 0.018	1.26AsnPro: 1.26 ± 0.017	0.619AsnGln: 0.619 ± 0.011	1.194AsnArg: 1.194 ± 0.018	1.454AsnSer: 1.454 ± 0.022	1.212AsnThr: 1.212 ± 0.018	1.595AsnVal: 1.595 ± 0.023	0.286AsnTrp: 0.286 ± 0.009	0.485AsnTyr: 0.485 ± 0.013	0.001AsnXaa: 0.001 ± 0.0
Pro	10.806ProAla: 10.806 ± 0.088	1.006ProCys: 1.006 ± 0.017	2.966ProAsp: 2.966 ± 0.025	3.221ProGlu: 3.221 ± 0.035	1.345ProPhe: 1.345 ± 0.016	6.476ProGly: 6.476 ± 0.051	1.701ProHis: 1.701 ± 0.021	1.268ProIle: 1.268 ± 0.016	1.485ProLys: 1.485 ± 0.026	6.238ProLeu: 6.238 ± 0.044	1.08ProMet: 1.08 ± 0.015	1.255ProAsn: 1.255 ± 0.019	9.323ProPro: 9.323 ± 0.131	3.115ProGln: 3.115 ± 0.039	4.219ProArg: 4.219 ± 0.035	5.66ProSer: 5.66 ± 0.056	3.233ProThr: 3.233 ± 0.03	3.655ProVal: 3.655 ± 0.028	0.885ProTrp: 0.885 ± 0.014	1.508ProTyr: 1.508 ± 0.022	0.004ProXaa: 0.004 ± 0.001
Gln	5.138GlnAla: 5.138 ± 0.046	0.565GlnCys: 0.565 ± 0.012	1.361GlnAsp: 1.361 ± 0.017	2.19GlnGlu: 2.19 ± 0.025	0.745GlnPhe: 0.745 ± 0.013	3.19GlnGly: 3.19 ± 0.032	1.629GlnHis: 1.629 ± 0.03	0.771GlnIle: 0.771 ± 0.014	0.907GlnLys: 0.907 ± 0.015	5.275GlnLeu: 5.275 ± 0.051	0.743GlnMet: 0.743 ± 0.013	0.597GlnAsn: 0.597 ± 0.013	3.846GlnPro: 3.846 ± 0.043	6.847GlnGln: 6.847 ± 0.117	3.678GlnArg: 3.678 ± 0.033	1.74GlnSer: 1.74 ± 0.019	1.202GlnThr: 1.202 ± 0.015	2.264GlnVal: 2.264 ± 0.022	0.499GlnTrp: 0.499 ± 0.011	0.798GlnTyr: 0.798 ± 0.017	0.001GlnXaa: 0.001 ± 0.0
Arg	8.377ArgAla: 8.377 ± 0.052	1.347ArgCys: 1.347 ± 0.016	2.845ArgAsp: 2.845 ± 0.031	3.373ArgGlu: 3.373 ± 0.038	1.702ArgPhe: 1.702 ± 0.019	6.207ArgGly: 6.207 ± 0.053	1.737ArgHis: 1.737 ± 0.019	1.691ArgIle: 1.691 ± 0.021	1.899ArgLys: 1.899 ± 0.021	7.536ArgLeu: 7.536 ± 0.057	1.472ArgMet: 1.472 ± 0.016	1.409ArgAsn: 1.409 ± 0.018	4.708ArgPro: 4.708 ± 0.037	3.411ArgGln: 3.411 ± 0.03	6.327ArgArg: 6.327 ± 0.053	4.716ArgSer: 4.716 ± 0.039	3.168ArgThr: 3.168 ± 0.028	4.223ArgVal: 4.223 ± 0.03	1.076ArgTrp: 1.076 ± 0.018	1.304ArgTyr: 1.304 ± 0.015	0.003ArgXaa: 0.003 ± 0.001
Ser	9.363SerAla: 9.363 ± 0.067	1.353SerCys: 1.353 ± 0.019	2.9SerAsp: 2.9 ± 0.028	2.811SerGlu: 2.811 ± 0.025	1.836SerPhe: 1.836 ± 0.02	8.182SerGly: 8.182 ± 0.06	1.292SerHis: 1.292 ± 0.015	1.865SerIle: 1.865 ± 0.025	1.874SerLys: 1.874 ± 0.021	5.9SerLeu: 5.9 ± 0.04	1.402SerMet: 1.402 ± 0.018	1.716SerAsn: 1.716 ± 0.05	5.111SerPro: 5.111 ± 0.058	2.111SerGln: 2.111 ± 0.022	4.544SerArg: 4.544 ± 0.036	7.428SerSer: 7.428 ± 0.068	3.824SerThr: 3.824 ± 0.03	3.951SerVal: 3.951 ± 0.029	0.93SerTrp: 0.93 ± 0.014	1.581SerTyr: 1.581 ± 0.019	0.002SerXaa: 0.002 ± 0.001
Thr	7.332ThrAla: 7.332 ± 0.049	0.906ThrCys: 0.906 ± 0.016	2.037ThrAsp: 2.037 ± 0.021	1.855ThrGlu: 1.855 ± 0.018	1.364ThrPhe: 1.364 ± 0.018	3.991ThrGly: 3.991 ± 0.036	0.938ThrHis: 0.938 ± 0.017	1.398ThrIle: 1.398 ± 0.022	1.223ThrLys: 1.223 ± 0.018	4.454ThrLeu: 4.454 ± 0.033	0.861ThrMet: 0.861 ± 0.013	1.056ThrAsn: 1.056 ± 0.015	3.252ThrPro: 3.252 ± 0.032	1.455ThrGln: 1.455 ± 0.017	2.679ThrArg: 2.679 ± 0.027	3.633ThrSer: 3.633 ± 0.036	2.821ThrThr: 2.821 ± 0.038	3.162ThrVal: 3.162 ± 0.026	0.673ThrTrp: 0.673 ± 0.012	1.024ThrTyr: 1.024 ± 0.016	0.002ThrXaa: 0.002 ± 0.001
Val	9.433ValAla: 9.433 ± 0.063	1.178ValCys: 1.178 ± 0.021	3.107ValAsp: 3.107 ± 0.028	3.737ValGlu: 3.737 ± 0.026	1.733ValPhe: 1.733 ± 0.021	5.032ValGly: 5.032 ± 0.033	1.427ValHis: 1.427 ± 0.019	1.627ValIle: 1.627 ± 0.021	1.906ValLys: 1.906 ± 0.024	7.2ValLeu: 7.2 ± 0.045	1.41ValMet: 1.41 ± 0.016	1.405ValAsn: 1.405 ± 0.018	3.996ValPro: 3.996 ± 0.036	2.645ValGln: 2.645 ± 0.02	4.661ValArg: 4.661 ± 0.031	3.883ValSer: 3.883 ± 0.03	3.104ValThr: 3.104 ± 0.032	5.448ValVal: 5.448 ± 0.045	0.951ValTrp: 0.951 ± 0.012	1.383ValTyr: 1.383 ± 0.02	0.002ValXaa: 0.002 ± 0.001
Trp	1.588TrpAla: 1.588 ± 0.016	0.266TrpCys: 0.266 ± 0.008	0.726TrpAsp: 0.726 ± 0.013	0.668TrpGlu: 0.668 ± 0.014	0.331TrpPhe: 0.331 ± 0.009	1.149TrpGly: 1.149 ± 0.019	0.343TrpHis: 0.343 ± 0.009	0.283TrpIle: 0.283 ± 0.007	0.36TrpLys: 0.36 ± 0.009	1.789TrpLeu: 1.789 ± 0.037	0.284TrpMet: 0.284 ± 0.008	0.311TrpAsn: 0.311 ± 0.008	0.774TrpPro: 0.774 ± 0.012	0.62TrpGln: 0.62 ± 0.012	1.346TrpArg: 1.346 ± 0.019	0.854TrpSer: 0.854 ± 0.014	0.578TrpThr: 0.578 ± 0.011	0.822TrpVal: 0.822 ± 0.012	0.266TrpTrp: 0.266 ± 0.008	0.317TrpTyr: 0.317 ± 0.008	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.819TyrAla: 1.819 ± 0.018	0.43TyrCys: 0.43 ± 0.009	1.35TyrAsp: 1.35 ± 0.018	1.001TyrGlu: 1.001 ± 0.015	0.623TyrPhe: 0.623 ± 0.011	2.294TyrGly: 2.294 ± 0.026	0.444TyrHis: 0.444 ± 0.01	0.627TyrIle: 0.627 ± 0.013	0.669TyrLys: 0.669 ± 0.013	1.754TyrLeu: 1.754 ± 0.021	0.489TyrMet: 0.489 ± 0.011	0.668TyrAsn: 0.668 ± 0.013	0.944TyrPro: 0.944 ± 0.016	0.682TyrGln: 0.682 ± 0.012	1.235TyrArg: 1.235 ± 0.018	1.306TyrSer: 1.306 ± 0.019	1.071TyrThr: 1.071 ± 0.017	1.321TyrVal: 1.321 ± 0.017	0.249TyrTrp: 0.249 ± 0.007	0.539TyrTyr: 0.539 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.005XaaAla: 0.005 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.001	0.001XaaPhe: 0.001 ± 0.0	0.006XaaGly: 0.006 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.003XaaLeu: 0.003 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.004XaaPro: 0.004 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.002XaaArg: 0.002 ± 0.001	0.002XaaSer: 0.002 ± 0.001	0.002XaaThr: 0.002 ± 0.0	0.003XaaVal: 0.003 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.008XaaXaa: 0.008 ± 0.003

Statistics based on 14121 proteins (5766222 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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