Amino acid dipepetide frequency for Bark beetle-associated genomovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.762AlaAla: 4.762 ± 1.142
0.0AlaCys: 0.0 ± 0.0
9.524AlaAsp: 9.524 ± 2.096
3.175AlaGlu: 3.175 ± 2.158
0.0AlaPhe: 0.0 ± 0.0
11.111AlaGly: 11.111 ± 0.985
0.0AlaHis: 0.0 ± 0.0
4.762AlaIle: 4.762 ± 1.048
6.349AlaLys: 6.349 ± 2.252
3.175AlaLeu: 3.175 ± 2.158
1.587AlaMet: 1.587 ± 1.11
7.937AlaAsn: 7.937 ± 3.206
1.587AlaPro: 1.587 ± 1.079
1.587AlaGln: 1.587 ± 1.079
9.524AlaArg: 9.524 ± 0.094
4.762AlaSer: 4.762 ± 1.142
14.286AlaThr: 14.286 ± 5.615
4.762AlaVal: 4.762 ± 1.142
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.587CysAla: 1.587 ± 1.11
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.587CysGlu: 1.587 ± 1.079
1.587CysPhe: 1.587 ± 1.11
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.587CysIle: 1.587 ± 1.079
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.587CysAsn: 1.587 ± 1.079
1.587CysPro: 1.587 ± 1.11
1.587CysGln: 1.587 ± 1.079
0.0CysArg: 0.0 ± 0.0
1.587CysSer: 1.587 ± 1.079
0.0CysThr: 0.0 ± 0.0
1.587CysVal: 1.587 ± 1.11
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.175AspAla: 3.175 ± 0.031
0.0AspCys: 0.0 ± 0.0
6.349AspAsp: 6.349 ± 0.063
3.175AspGlu: 3.175 ± 0.031
1.587AspPhe: 1.587 ± 1.079
6.349AspGly: 6.349 ± 4.317
0.0AspHis: 0.0 ± 0.0
7.937AspIle: 7.937 ± 3.206
0.0AspLys: 0.0 ± 0.0
4.762AspLeu: 4.762 ± 1.048
1.587AspMet: 1.587 ± 1.079
3.175AspAsn: 3.175 ± 0.031
7.937AspPro: 7.937 ± 3.206
3.175AspGln: 3.175 ± 2.221
3.175AspArg: 3.175 ± 2.221
0.0AspSer: 0.0 ± 0.0
4.762AspThr: 4.762 ± 1.142
6.349AspVal: 6.349 ± 0.063
6.349AspTrp: 6.349 ± 2.127
3.175AspTyr: 3.175 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
4.762GluAla: 4.762 ± 1.048
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
1.587GluGlu: 1.587 ± 1.079
3.175GluPhe: 3.175 ± 2.158
0.0GluGly: 0.0 ± 0.0
1.587GluHis: 1.587 ± 1.079
3.175GluIle: 3.175 ± 2.158
1.587GluLys: 1.587 ± 1.11
1.587GluLeu: 1.587 ± 1.079
1.587GluMet: 1.587 ± 1.719
1.587GluAsn: 1.587 ± 1.11
1.587GluPro: 1.587 ± 1.079
1.587GluGln: 1.587 ± 1.079
3.175GluArg: 3.175 ± 0.031
0.0GluSer: 0.0 ± 0.0
1.587GluThr: 1.587 ± 1.079
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
1.587GluTyr: 1.587 ± 1.079
0.0GluXaa: 0.0 ± 0.0
Phe
9.524PheAla: 9.524 ± 4.286
1.587PheCys: 1.587 ± 1.11
6.349PheAsp: 6.349 ± 2.127
0.0PheGlu: 0.0 ± 0.0
3.175PhePhe: 3.175 ± 2.158
6.349PheGly: 6.349 ± 4.317
4.762PheHis: 4.762 ± 3.238
0.0PheIle: 0.0 ± 0.0
4.762PheLys: 4.762 ± 1.048
3.175PheLeu: 3.175 ± 2.158
3.175PheMet: 3.175 ± 0.031
1.587PheAsn: 1.587 ± 1.11
1.587PhePro: 1.587 ± 1.079
0.0PheGln: 0.0 ± 0.0
3.175PheArg: 3.175 ± 0.031
3.175PheSer: 3.175 ± 0.031
1.587PheThr: 1.587 ± 1.11
1.587PheVal: 1.587 ± 1.079
0.0PheTrp: 0.0 ± 0.0
1.587PheTyr: 1.587 ± 1.11
0.0PheXaa: 0.0 ± 0.0
Gly
6.349GlyAla: 6.349 ± 0.063
1.587GlyCys: 1.587 ± 1.079
4.762GlyAsp: 4.762 ± 1.048
0.0GlyGlu: 0.0 ± 0.0
1.587GlyPhe: 1.587 ± 1.079
9.524GlyGly: 9.524 ± 0.094
1.587GlyHis: 1.587 ± 1.11
3.175GlyIle: 3.175 ± 2.158
3.175GlyLys: 3.175 ± 0.031
4.762GlyLeu: 4.762 ± 1.142
3.175GlyMet: 3.175 ± 2.221
4.762GlyAsn: 4.762 ± 1.142
3.175GlyPro: 3.175 ± 0.031
1.587GlyGln: 1.587 ± 1.079
7.937GlyArg: 7.937 ± 5.396
1.587GlySer: 1.587 ± 1.079
1.587GlyThr: 1.587 ± 1.079
7.937GlyVal: 7.937 ± 3.206
1.587GlyTrp: 1.587 ± 1.11
4.762GlyTyr: 4.762 ± 1.142
0.0GlyXaa: 0.0 ± 0.0
His
1.587HisAla: 1.587 ± 1.079
1.587HisCys: 1.587 ± 1.079
3.175HisAsp: 3.175 ± 2.158
1.587HisGlu: 1.587 ± 1.11
3.175HisPhe: 3.175 ± 0.031
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.175HisLeu: 3.175 ± 2.158
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.587HisPro: 1.587 ± 1.079
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.587HisSer: 1.587 ± 1.079
0.0HisThr: 0.0 ± 0.0
3.175HisVal: 3.175 ± 2.158
0.0HisTrp: 0.0 ± 0.0
1.587HisTyr: 1.587 ± 1.079
0.0HisXaa: 0.0 ± 0.0
Ile
3.175IleAla: 3.175 ± 2.158
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
0.0IleGlu: 0.0 ± 0.0
7.937IlePhe: 7.937 ± 3.206
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
4.762IleIle: 4.762 ± 1.142
6.349IleLys: 6.349 ± 0.063
4.762IleLeu: 4.762 ± 1.048
0.0IleMet: 0.0 ± 0.0
3.175IleAsn: 3.175 ± 0.031
0.0IlePro: 0.0 ± 0.0
3.175IleGln: 3.175 ± 0.031
0.0IleArg: 0.0 ± 0.0
3.175IleSer: 3.175 ± 2.158
4.762IleThr: 4.762 ± 1.142
3.175IleVal: 3.175 ± 0.031
1.587IleTrp: 1.587 ± 1.079
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.587LysAla: 1.587 ± 1.11
0.0LysCys: 0.0 ± 0.0
3.175LysAsp: 3.175 ± 2.158
3.175LysGlu: 3.175 ± 0.031
6.349LysPhe: 6.349 ± 2.127
3.175LysGly: 3.175 ± 2.221
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
4.762LysLys: 4.762 ± 3.331
1.587LysLeu: 1.587 ± 1.11
3.175LysMet: 3.175 ± 1.763
3.175LysAsn: 3.175 ± 2.221
3.175LysPro: 3.175 ± 2.221
1.587LysGln: 1.587 ± 1.11
1.587LysArg: 1.587 ± 1.11
3.175LysSer: 3.175 ± 0.031
4.762LysThr: 4.762 ± 1.142
1.587LysVal: 1.587 ± 1.11
3.175LysTrp: 3.175 ± 2.158
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.349LeuAla: 6.349 ± 2.127
1.587LeuCys: 1.587 ± 1.079
4.762LeuAsp: 4.762 ± 3.238
3.175LeuGlu: 3.175 ± 2.158
1.587LeuPhe: 1.587 ± 1.079
6.349LeuGly: 6.349 ± 4.317
0.0LeuHis: 0.0 ± 0.0
1.587LeuIle: 1.587 ± 1.079
0.0LeuLys: 0.0 ± 0.0
1.587LeuLeu: 1.587 ± 1.11
0.0LeuMet: 0.0 ± 0.0
1.587LeuAsn: 1.587 ± 1.11
1.587LeuPro: 1.587 ± 1.11
1.587LeuGln: 1.587 ± 1.11
1.587LeuArg: 1.587 ± 1.11
1.587LeuSer: 1.587 ± 1.11
1.587LeuThr: 1.587 ± 1.11
9.524LeuVal: 9.524 ± 2.096
6.349LeuTrp: 6.349 ± 2.252
4.762LeuTyr: 4.762 ± 1.142
0.0LeuXaa: 0.0 ± 0.0
Met
3.175MetAla: 3.175 ± 2.221
1.587MetCys: 1.587 ± 1.11
0.0MetAsp: 0.0 ± 0.0
1.587MetGlu: 1.587 ± 1.079
0.0MetPhe: 0.0 ± 0.0
3.175MetGly: 3.175 ± 0.031
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.587MetLeu: 1.587 ± 1.11
0.0MetMet: 0.0 ± 0.0
3.175MetAsn: 3.175 ± 2.221
1.587MetPro: 1.587 ± 1.079
0.0MetGln: 0.0 ± 0.0
1.587MetArg: 1.587 ± 1.11
3.175MetSer: 3.175 ± 2.221
1.587MetThr: 1.587 ± 1.079
1.587MetVal: 1.587 ± 1.079
0.0MetTrp: 0.0 ± 0.0
1.587MetTyr: 1.587 ± 1.079
0.0MetXaa: 0.0 ± 0.0
Asn
6.349AsnAla: 6.349 ± 0.063
1.587AsnCys: 1.587 ± 1.079
1.587AsnAsp: 1.587 ± 1.11
0.0AsnGlu: 0.0 ± 0.0
3.175AsnPhe: 3.175 ± 0.031
3.175AsnGly: 3.175 ± 2.221
1.587AsnHis: 1.587 ± 1.079
1.587AsnIle: 1.587 ± 1.079
3.175AsnLys: 3.175 ± 2.221
4.762AsnLeu: 4.762 ± 3.331
1.587AsnMet: 1.587 ± 1.11
3.175AsnAsn: 3.175 ± 2.221
0.0AsnPro: 0.0 ± 0.0
3.175AsnGln: 3.175 ± 2.221
1.587AsnArg: 1.587 ± 1.079
6.349AsnSer: 6.349 ± 2.252
3.175AsnThr: 3.175 ± 0.031
1.587AsnVal: 1.587 ± 1.11
0.0AsnTrp: 0.0 ± 0.0
1.587AsnTyr: 1.587 ± 1.079
0.0AsnXaa: 0.0 ± 0.0
Pro
3.175ProAla: 3.175 ± 0.031
0.0ProCys: 0.0 ± 0.0
1.587ProAsp: 1.587 ± 1.079
3.175ProGlu: 3.175 ± 2.158
3.175ProPhe: 3.175 ± 2.158
3.175ProGly: 3.175 ± 2.221
1.587ProHis: 1.587 ± 1.079
1.587ProIle: 1.587 ± 1.079
0.0ProLys: 0.0 ± 0.0
3.175ProLeu: 3.175 ± 0.031
1.587ProMet: 1.587 ± 1.11
1.587ProAsn: 1.587 ± 1.079
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
6.349ProArg: 6.349 ± 0.063
6.349ProSer: 6.349 ± 2.127
4.762ProThr: 4.762 ± 3.331
1.587ProVal: 1.587 ± 1.079
1.587ProTrp: 1.587 ± 1.11
3.175ProTyr: 3.175 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
3.175GlnAla: 3.175 ± 2.221
0.0GlnCys: 0.0 ± 0.0
4.762GlnAsp: 4.762 ± 3.331
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
1.587GlnIle: 1.587 ± 1.079
1.587GlnLys: 1.587 ± 1.079
0.0GlnLeu: 0.0 ± 0.0
1.587GlnMet: 1.587 ± 1.079
0.0GlnAsn: 0.0 ± 0.0
1.587GlnPro: 1.587 ± 1.079
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
0.0GlnSer: 0.0 ± 0.0
1.587GlnThr: 1.587 ± 1.11
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
3.175GlnTyr: 3.175 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
1.587ArgAla: 1.587 ± 1.079
0.0ArgCys: 0.0 ± 0.0
7.937ArgAsp: 7.937 ± 5.396
0.0ArgGlu: 0.0 ± 0.0
3.175ArgPhe: 3.175 ± 2.158
3.175ArgGly: 3.175 ± 0.031
1.587ArgHis: 1.587 ± 1.079
4.762ArgIle: 4.762 ± 3.331
7.937ArgLys: 7.937 ± 3.363
3.175ArgLeu: 3.175 ± 0.031
1.587ArgMet: 1.587 ± 1.079
0.0ArgAsn: 0.0 ± 0.0
4.762ArgPro: 4.762 ± 1.048
0.0ArgGln: 0.0 ± 0.0
9.524ArgArg: 9.524 ± 4.473
14.286ArgSer: 14.286 ± 3.425
4.762ArgThr: 4.762 ± 1.142
0.0ArgVal: 0.0 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
3.175ArgTyr: 3.175 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
4.762SerAla: 4.762 ± 1.142
0.0SerCys: 0.0 ± 0.0
6.349SerAsp: 6.349 ± 2.252
1.587SerGlu: 1.587 ± 1.11
1.587SerPhe: 1.587 ± 1.079
1.587SerGly: 1.587 ± 1.079
1.587SerHis: 1.587 ± 1.079
3.175SerIle: 3.175 ± 0.031
3.175SerLys: 3.175 ± 0.031
7.937SerLeu: 7.937 ± 3.206
1.587SerMet: 1.587 ± 1.11
3.175SerAsn: 3.175 ± 2.221
7.937SerPro: 7.937 ± 1.017
0.0SerGln: 0.0 ± 0.0
14.286SerArg: 14.286 ± 3.425
7.937SerSer: 7.937 ± 3.363
4.762SerThr: 4.762 ± 3.331
1.587SerVal: 1.587 ± 1.11
1.587SerTrp: 1.587 ± 1.11
3.175SerTyr: 3.175 ± 2.221
0.0SerXaa: 0.0 ± 0.0
Thr
7.937ThrAla: 7.937 ± 3.363
3.175ThrCys: 3.175 ± 2.221
3.175ThrAsp: 3.175 ± 0.031
1.587ThrGlu: 1.587 ± 1.079
3.175ThrPhe: 3.175 ± 2.221
4.762ThrGly: 4.762 ± 1.142
1.587ThrHis: 1.587 ± 1.079
3.175ThrIle: 3.175 ± 2.221
1.587ThrLys: 1.587 ± 1.11
3.175ThrLeu: 3.175 ± 0.031
0.0ThrMet: 0.0 ± 0.0
3.175ThrAsn: 3.175 ± 2.221
4.762ThrPro: 4.762 ± 1.142
0.0ThrGln: 0.0 ± 0.0
1.587ThrArg: 1.587 ± 1.079
7.937ThrSer: 7.937 ± 5.552
6.349ThrThr: 6.349 ± 4.442
4.762ThrVal: 4.762 ± 1.142
1.587ThrTrp: 1.587 ± 1.079
1.587ThrTyr: 1.587 ± 1.079
0.0ThrXaa: 0.0 ± 0.0
Val
7.937ValAla: 7.937 ± 1.017
1.587ValCys: 1.587 ± 1.079
6.349ValAsp: 6.349 ± 2.252
6.349ValGlu: 6.349 ± 4.317
7.937ValPhe: 7.937 ± 1.017
4.762ValGly: 4.762 ± 1.142
1.587ValHis: 1.587 ± 1.079
1.587ValIle: 1.587 ± 1.11
3.175ValLys: 3.175 ± 0.031
0.0ValLeu: 0.0 ± 0.0
1.587ValMet: 1.587 ± 1.11
1.587ValAsn: 1.587 ± 1.11
1.587ValPro: 1.587 ± 1.11
0.0ValGln: 0.0 ± 0.0
0.0ValArg: 0.0 ± 0.0
3.175ValSer: 3.175 ± 0.031
3.175ValThr: 3.175 ± 0.031
4.762ValVal: 4.762 ± 1.142
1.587ValTrp: 1.587 ± 1.079
3.175ValTyr: 3.175 ± 2.221
0.0ValXaa: 0.0 ± 0.0
Trp
1.587TrpAla: 1.587 ± 1.11
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.587TrpPhe: 1.587 ± 1.11
4.762TrpGly: 4.762 ± 3.238
3.175TrpHis: 3.175 ± 0.031
1.587TrpIle: 1.587 ± 1.079
0.0TrpLys: 0.0 ± 0.0
4.762TrpLeu: 4.762 ± 1.048
0.0TrpMet: 0.0 ± 0.0
1.587TrpAsn: 1.587 ± 1.11
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
4.762TrpArg: 4.762 ± 1.048
1.587TrpSer: 1.587 ± 1.11
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.587TrpTyr: 1.587 ± 1.11
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.349TyrAla: 6.349 ± 2.127
0.0TyrCys: 0.0 ± 0.0
3.175TyrAsp: 3.175 ± 0.031
0.0TyrGlu: 0.0 ± 0.0
3.175TyrPhe: 3.175 ± 2.158
3.175TyrGly: 3.175 ± 0.031
1.587TyrHis: 1.587 ± 1.079
0.0TyrIle: 0.0 ± 0.0
1.587TyrLys: 1.587 ± 1.11
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
3.175TyrAsn: 3.175 ± 0.031
1.587TyrPro: 1.587 ± 1.11
0.0TyrGln: 0.0 ± 0.0
1.587TyrArg: 1.587 ± 1.079
6.349TyrSer: 6.349 ± 2.252
0.0TyrThr: 0.0 ± 0.0
6.349TyrVal: 6.349 ± 4.442
1.587TyrTrp: 1.587 ± 1.11
3.175TyrTyr: 3.175 ± 2.221
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (631 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski