Amino acid dipepetide frequency for Calibrachoa mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.33AlaAla: 5.33 ± 1.261
1.332AlaCys: 1.332 ± 0.815
2.665AlaAsp: 2.665 ± 0.547
7.328AlaGlu: 7.328 ± 1.721
2.665AlaPhe: 2.665 ± 1.019
2.665AlaGly: 2.665 ± 1.27
3.331AlaHis: 3.331 ± 0.69
2.665AlaIle: 2.665 ± 1.175
5.996AlaLys: 5.996 ± 1.876
8.661AlaLeu: 8.661 ± 2.643
0.666AlaMet: 0.666 ± 0.407
4.664AlaAsn: 4.664 ± 0.991
1.332AlaPro: 1.332 ± 0.815
0.0AlaGln: 0.0 ± 0.0
4.664AlaArg: 4.664 ± 2.252
1.999AlaSer: 1.999 ± 1.344
1.332AlaThr: 1.332 ± 1.528
6.662AlaVal: 6.662 ± 1.403
1.999AlaTrp: 1.999 ± 0.912
5.996AlaTyr: 5.996 ± 1.372
0.0AlaXaa: 0.0 ± 0.0
Cys
1.332CysAla: 1.332 ± 0.8
1.332CysCys: 1.332 ± 0.8
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.332CysPhe: 1.332 ± 0.8
2.665CysGly: 2.665 ± 1.674
0.666CysHis: 0.666 ± 0.407
3.997CysIle: 3.997 ± 1.78
0.0CysLys: 0.0 ± 0.0
0.666CysLeu: 0.666 ± 0.407
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.666CysPro: 0.666 ± 0.407
1.332CysGln: 1.332 ± 0.815
3.331CysArg: 3.331 ± 0.69
0.0CysSer: 0.0 ± 0.0
3.331CysThr: 3.331 ± 0.69
1.999CysVal: 1.999 ± 0.912
0.0CysTrp: 0.0 ± 0.0
1.332CysTyr: 1.332 ± 0.815
0.0CysXaa: 0.0 ± 0.0
Asp
5.996AspAla: 5.996 ± 2.735
2.665AspCys: 2.665 ± 1.63
5.996AspAsp: 5.996 ± 3.241
1.332AspGlu: 1.332 ± 0.8
1.332AspPhe: 1.332 ± 1.661
3.997AspGly: 3.997 ± 2.026
0.0AspHis: 0.0 ± 0.0
1.999AspIle: 1.999 ± 0.674
2.665AspLys: 2.665 ± 1.141
3.331AspLeu: 3.331 ± 1.666
1.332AspMet: 1.332 ± 0.815
0.666AspAsn: 0.666 ± 0.764
1.999AspPro: 1.999 ± 1.344
1.999AspGln: 1.999 ± 1.222
1.332AspArg: 1.332 ± 0.815
4.664AspSer: 4.664 ± 2.646
1.999AspThr: 1.999 ± 0.912
0.666AspVal: 0.666 ± 0.764
0.0AspTrp: 0.0 ± 0.0
0.666AspTyr: 0.666 ± 0.764
0.0AspXaa: 0.0 ± 0.0
Glu
1.999GluAla: 1.999 ± 0.745
0.0GluCys: 0.0 ± 0.0
2.665GluAsp: 2.665 ± 1.6
1.332GluGlu: 1.332 ± 0.815
2.665GluPhe: 2.665 ± 0.547
3.331GluGly: 3.331 ± 0.966
3.331GluHis: 3.331 ± 1.231
4.664GluIle: 4.664 ± 2.498
6.662GluLys: 6.662 ± 2.381
7.995GluLeu: 7.995 ± 2.428
1.332GluMet: 1.332 ± 0.8
1.332GluAsn: 1.332 ± 0.635
3.997GluPro: 3.997 ± 1.179
1.999GluGln: 1.999 ± 1.241
2.665GluArg: 2.665 ± 1.364
4.664GluSer: 4.664 ± 1.49
0.0GluThr: 0.0 ± 0.0
5.33GluVal: 5.33 ± 1.982
0.0GluTrp: 0.0 ± 0.0
1.332GluTyr: 1.332 ± 0.8
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.332PheCys: 1.332 ± 0.815
1.999PheAsp: 1.999 ± 1.558
1.332PheGlu: 1.332 ± 0.635
0.666PhePhe: 0.666 ± 1.635
3.997PheGly: 3.997 ± 0.992
3.997PheHis: 3.997 ± 1.652
1.999PheIle: 1.999 ± 0.674
1.999PheLys: 1.999 ± 1.344
1.999PheLeu: 1.999 ± 0.912
0.666PheMet: 0.666 ± 1.035
1.332PheAsn: 1.332 ± 0.8
1.999PhePro: 1.999 ± 1.558
2.665PheGln: 2.665 ± 1.6
2.665PheArg: 2.665 ± 1.198
1.999PheSer: 1.999 ± 0.745
3.997PheThr: 3.997 ± 1.73
3.331PheVal: 3.331 ± 1.361
0.0PheTrp: 0.0 ± 0.0
1.332PheTyr: 1.332 ± 0.815
0.0PheXaa: 0.0 ± 0.0
Gly
4.664GlyAla: 4.664 ± 1.49
0.0GlyCys: 0.0 ± 0.0
3.331GlyAsp: 3.331 ± 1.322
3.331GlyGlu: 3.331 ± 1.959
2.665GlyPhe: 2.665 ± 1.164
6.662GlyGly: 6.662 ± 2.508
0.666GlyHis: 0.666 ± 0.407
4.664GlyIle: 4.664 ± 1.351
7.328GlyLys: 7.328 ± 1.497
3.997GlyLeu: 3.997 ± 1.179
3.331GlyMet: 3.331 ± 1.136
1.332GlyAsn: 1.332 ± 0.815
1.999GlyPro: 1.999 ± 1.344
2.665GlyGln: 2.665 ± 0.547
5.996GlyArg: 5.996 ± 0.963
3.331GlySer: 3.331 ± 3.368
1.999GlyThr: 1.999 ± 0.674
5.996GlyVal: 5.996 ± 1.523
0.666GlyTrp: 0.666 ± 0.407
1.999GlyTyr: 1.999 ± 1.344
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.666HisAsp: 0.666 ± 1.635
2.665HisGlu: 2.665 ± 1.164
2.665HisPhe: 2.665 ± 2.193
0.0HisGly: 0.0 ± 0.0
1.999HisHis: 1.999 ± 0.912
1.999HisIle: 1.999 ± 0.674
3.997HisLys: 3.997 ± 2.399
1.332HisLeu: 1.332 ± 0.815
1.999HisMet: 1.999 ± 0.912
0.666HisAsn: 0.666 ± 0.407
2.665HisPro: 2.665 ± 1.141
1.332HisGln: 1.332 ± 0.8
0.0HisArg: 0.0 ± 0.0
0.666HisSer: 0.666 ± 0.407
2.665HisThr: 2.665 ± 1.164
1.332HisVal: 1.332 ± 1.544
0.0HisTrp: 0.0 ± 0.0
0.666HisTyr: 0.666 ± 0.764
0.0HisXaa: 0.0 ± 0.0
Ile
3.331IleAla: 3.331 ± 1.359
0.0IleCys: 0.0 ± 0.0
1.999IleAsp: 1.999 ± 1.222
2.665IleGlu: 2.665 ± 1.164
1.332IlePhe: 1.332 ± 1.544
0.666IleGly: 0.666 ± 1.635
0.666IleHis: 0.666 ± 1.141
1.332IleIle: 1.332 ± 0.635
3.997IleLys: 3.997 ± 2.691
6.662IleLeu: 6.662 ± 0.997
0.0IleMet: 0.0 ± 0.0
2.665IleAsn: 2.665 ± 3.513
4.664IlePro: 4.664 ± 1.855
0.666IleGln: 0.666 ± 0.407
1.999IleArg: 1.999 ± 0.912
6.662IleSer: 6.662 ± 2.445
5.33IleThr: 5.33 ± 2.05
1.999IleVal: 1.999 ± 2.292
1.999IleTrp: 1.999 ± 0.912
1.332IleTyr: 1.332 ± 0.635
0.0IleXaa: 0.0 ± 0.0
Lys
9.993LysAla: 9.993 ± 2.019
0.0LysCys: 0.0 ± 0.0
4.664LysAsp: 4.664 ± 1.722
6.662LysGlu: 6.662 ± 2.508
2.665LysPhe: 2.665 ± 0.547
4.664LysGly: 4.664 ± 0.962
2.665LysHis: 2.665 ± 1.642
2.665LysIle: 2.665 ± 1.674
1.999LysLys: 1.999 ± 0.745
5.33LysLeu: 5.33 ± 2.35
1.999LysMet: 1.999 ± 1.165
3.997LysAsn: 3.997 ± 1.42
3.331LysPro: 3.331 ± 1.361
3.331LysGln: 3.331 ± 0.959
3.997LysArg: 3.997 ± 0.992
1.332LysSer: 1.332 ± 1.426
5.33LysThr: 5.33 ± 3.326
3.997LysVal: 3.997 ± 0.992
1.332LysTrp: 1.332 ± 1.528
3.997LysTyr: 3.997 ± 1.348
0.666LysXaa: 0.666 ± 0.407
Leu
11.326LeuAla: 11.326 ± 2.472
3.331LeuCys: 3.331 ± 1.663
2.665LeuAsp: 2.665 ± 0.547
8.661LeuGlu: 8.661 ± 2.477
1.332LeuPhe: 1.332 ± 0.815
5.996LeuGly: 5.996 ± 1.224
2.665LeuHis: 2.665 ± 1.6
4.664LeuIle: 4.664 ± 1.703
5.33LeuLys: 5.33 ± 1.731
7.995LeuLeu: 7.995 ± 1.543
1.332LeuMet: 1.332 ± 1.962
3.331LeuAsn: 3.331 ± 1.978
2.665LeuPro: 2.665 ± 0.547
5.33LeuGln: 5.33 ± 2.601
3.331LeuArg: 3.331 ± 1.873
1.999LeuSer: 1.999 ± 1.159
7.328LeuThr: 7.328 ± 2.938
3.997LeuVal: 3.997 ± 2.627
0.0LeuTrp: 0.0 ± 0.0
0.666LeuTyr: 0.666 ± 0.407
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.666MetCys: 0.666 ± 0.407
1.332MetAsp: 1.332 ± 0.635
1.332MetGlu: 1.332 ± 2.282
0.666MetPhe: 0.666 ± 0.764
1.332MetGly: 1.332 ± 0.8
0.666MetHis: 0.666 ± 0.764
0.666MetIle: 0.666 ± 0.407
1.999MetLys: 1.999 ± 0.912
1.332MetLeu: 1.332 ± 1.544
0.0MetMet: 0.0 ± 0.0
3.997MetAsn: 3.997 ± 1.179
1.332MetPro: 1.332 ± 0.815
0.666MetGln: 0.666 ± 0.407
1.332MetArg: 1.332 ± 0.8
3.331MetSer: 3.331 ± 1.361
0.0MetThr: 0.0 ± 0.0
3.331MetVal: 3.331 ± 1.666
0.0MetTrp: 0.0 ± 0.0
1.332MetTyr: 1.332 ± 0.635
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
2.665AsnCys: 2.665 ± 1.642
0.666AsnAsp: 0.666 ± 0.764
1.332AsnGlu: 1.332 ± 1.075
0.0AsnPhe: 0.0 ± 0.0
2.665AsnGly: 2.665 ± 1.164
1.332AsnHis: 1.332 ± 0.8
3.331AsnIle: 3.331 ± 3.097
5.996AsnLys: 5.996 ± 2.471
1.999AsnLeu: 1.999 ± 0.745
0.0AsnMet: 0.0 ± 0.0
1.999AsnAsn: 1.999 ± 1.222
0.666AsnPro: 0.666 ± 0.764
1.332AsnGln: 1.332 ± 1.661
3.331AsnArg: 3.331 ± 1.266
4.664AsnSer: 4.664 ± 1.105
1.332AsnThr: 1.332 ± 1.544
4.664AsnVal: 4.664 ± 1.255
0.0AsnTrp: 0.0 ± 0.0
3.331AsnTyr: 3.331 ± 0.69
0.0AsnXaa: 0.0 ± 0.0
Pro
3.331ProAla: 3.331 ± 0.69
0.0ProCys: 0.0 ± 0.0
3.997ProAsp: 3.997 ± 1.179
2.665ProGlu: 2.665 ± 1.63
3.331ProPhe: 3.331 ± 1.266
4.664ProGly: 4.664 ± 2.583
0.0ProHis: 0.0 ± 0.0
1.332ProIle: 1.332 ± 0.635
4.664ProLys: 4.664 ± 1.49
1.332ProLeu: 1.332 ± 0.635
0.0ProMet: 0.0 ± 0.0
2.665ProAsn: 2.665 ± 1.74
1.332ProPro: 1.332 ± 1.544
0.0ProGln: 0.0 ± 0.0
3.997ProArg: 3.997 ± 1.843
1.999ProSer: 1.999 ± 1.721
5.33ProThr: 5.33 ± 1.976
3.997ProVal: 3.997 ± 1.436
1.332ProTrp: 1.332 ± 0.635
1.332ProTyr: 1.332 ± 0.815
0.0ProXaa: 0.0 ± 0.0
Gln
3.331GlnAla: 3.331 ± 0.959
1.332GlnCys: 1.332 ± 0.8
0.666GlnAsp: 0.666 ± 0.407
0.0GlnGlu: 0.0 ± 0.0
3.997GlnPhe: 3.997 ± 1.843
1.332GlnGly: 1.332 ± 0.635
0.666GlnHis: 0.666 ± 0.407
0.0GlnIle: 0.0 ± 0.0
1.332GlnLys: 1.332 ± 0.635
5.33GlnLeu: 5.33 ± 1.211
1.332GlnMet: 1.332 ± 0.781
0.0GlnAsn: 0.0 ± 0.0
1.999GlnPro: 1.999 ± 0.745
3.997GlnGln: 3.997 ± 1.732
0.0GlnArg: 0.0 ± 0.0
5.33GlnSer: 5.33 ± 1.497
1.999GlnThr: 1.999 ± 0.745
4.664GlnVal: 4.664 ± 2.449
0.666GlnTrp: 0.666 ± 0.407
1.999GlnTyr: 1.999 ± 1.457
0.0GlnXaa: 0.0 ± 0.0
Arg
4.664ArgAla: 4.664 ± 1.936
2.665ArgCys: 2.665 ± 1.6
0.666ArgAsp: 0.666 ± 0.764
3.331ArgGlu: 3.331 ± 2.218
1.999ArgPhe: 1.999 ± 1.222
5.33ArgGly: 5.33 ± 1.211
1.999ArgHis: 1.999 ± 0.912
1.332ArgIle: 1.332 ± 0.635
2.665ArgLys: 2.665 ± 1.63
9.993ArgLeu: 9.993 ± 1.044
2.665ArgMet: 2.665 ± 1.164
3.997ArgAsn: 3.997 ± 1.823
0.0ArgPro: 0.0 ± 0.0
1.999ArgGln: 1.999 ± 0.912
4.664ArgArg: 4.664 ± 1.295
2.665ArgSer: 2.665 ± 1.642
2.665ArgThr: 2.665 ± 1.164
1.999ArgVal: 1.999 ± 1.222
1.332ArgTrp: 1.332 ± 1.661
2.665ArgTyr: 2.665 ± 1.019
0.0ArgXaa: 0.0 ± 0.0
Ser
2.665SerAla: 2.665 ± 1.27
0.666SerCys: 0.666 ± 0.407
3.997SerAsp: 3.997 ± 2.689
3.997SerGlu: 3.997 ± 0.874
2.665SerPhe: 2.665 ± 1.759
3.331SerGly: 3.331 ± 1.608
1.332SerHis: 1.332 ± 0.8
3.331SerIle: 3.331 ± 4.647
4.664SerLys: 4.664 ± 2.625
3.997SerLeu: 3.997 ± 1.486
1.332SerMet: 1.332 ± 0.635
2.665SerAsn: 2.665 ± 0.547
4.664SerPro: 4.664 ± 1.788
0.666SerGln: 0.666 ± 0.407
3.331SerArg: 3.331 ± 0.69
4.664SerSer: 4.664 ± 4.186
5.33SerThr: 5.33 ± 2.996
2.665SerVal: 2.665 ± 1.141
1.999SerTrp: 1.999 ± 0.745
3.331SerTyr: 3.331 ± 3.148
0.0SerXaa: 0.0 ± 0.0
Thr
4.664ThrAla: 4.664 ± 3.841
2.665ThrCys: 2.665 ± 1.019
1.332ThrAsp: 1.332 ± 0.8
3.331ThrGlu: 3.331 ± 1.487
1.999ThrPhe: 1.999 ± 0.745
2.665ThrGly: 2.665 ± 2.536
0.666ThrHis: 0.666 ± 1.635
2.665ThrIle: 2.665 ± 1.175
7.328ThrLys: 7.328 ± 1.224
4.664ThrLeu: 4.664 ± 1.788
0.0ThrMet: 0.0 ± 0.0
2.665ThrAsn: 2.665 ± 1.177
7.995ThrPro: 7.995 ± 1.429
1.332ThrGln: 1.332 ± 1.661
1.332ThrArg: 1.332 ± 0.635
3.997ThrSer: 3.997 ± 2.689
6.662ThrThr: 6.662 ± 3.786
5.33ThrVal: 5.33 ± 2.2
0.666ThrTrp: 0.666 ± 0.764
0.666ThrTyr: 0.666 ± 0.407
0.0ThrXaa: 0.0 ± 0.0
Val
6.662ValAla: 6.662 ± 1.942
1.999ValCys: 1.999 ± 0.912
3.997ValAsp: 3.997 ± 0.874
3.331ValGlu: 3.331 ± 1.361
3.997ValPhe: 3.997 ± 1.179
6.662ValGly: 6.662 ± 2.953
0.666ValHis: 0.666 ± 0.407
3.331ValIle: 3.331 ± 1.959
2.665ValLys: 2.665 ± 1.164
1.999ValLeu: 1.999 ± 1.344
3.331ValMet: 3.331 ± 0.69
1.332ValAsn: 1.332 ± 1.661
1.999ValPro: 1.999 ± 1.344
4.664ValGln: 4.664 ± 2.008
5.996ValArg: 5.996 ± 2.039
4.664ValSer: 4.664 ± 1.763
3.331ValThr: 3.331 ± 1.893
7.328ValVal: 7.328 ± 4.66
1.999ValTrp: 1.999 ± 0.674
1.332ValTyr: 1.332 ± 1.075
0.0ValXaa: 0.0 ± 0.0
Trp
0.666TrpAla: 0.666 ± 0.764
0.0TrpCys: 0.0 ± 0.0
0.666TrpAsp: 0.666 ± 0.407
1.332TrpGlu: 1.332 ± 0.8
1.332TrpPhe: 1.332 ± 0.8
0.666TrpGly: 0.666 ± 0.407
0.0TrpHis: 0.0 ± 0.0
0.666TrpIle: 0.666 ± 0.764
1.332TrpLys: 1.332 ± 0.8
1.332TrpLeu: 1.332 ± 0.635
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.666TrpPro: 0.666 ± 0.407
1.999TrpGln: 1.999 ± 1.344
1.332TrpArg: 1.332 ± 1.544
0.666TrpSer: 0.666 ± 0.407
0.666TrpThr: 0.666 ± 0.764
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.666TrpTyr: 0.666 ± 0.764
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.999TyrAla: 1.999 ± 0.674
1.332TyrCys: 1.332 ± 0.635
0.666TyrAsp: 0.666 ± 0.407
1.332TyrGlu: 1.332 ± 0.8
0.0TyrPhe: 0.0 ± 0.0
2.665TyrGly: 2.665 ± 1.759
0.0TyrHis: 0.0 ± 0.0
2.665TyrIle: 2.665 ± 1.642
1.999TyrLys: 1.999 ± 0.745
4.664TyrLeu: 4.664 ± 0.962
3.331TyrMet: 3.331 ± 0.69
1.999TyrAsn: 1.999 ± 1.344
1.332TyrPro: 1.332 ± 0.8
1.999TyrGln: 1.999 ± 1.222
3.997TyrArg: 3.997 ± 0.992
1.999TyrSer: 1.999 ± 3.206
1.999TyrThr: 1.999 ± 1.344
1.999TyrVal: 1.999 ± 0.745
0.0TyrTrp: 0.0 ± 0.0
1.332TyrTyr: 1.332 ± 1.544
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.666XaaGly: 0.666 ± 0.407
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1502 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski