Amino acid dipepetide frequency for Armillaria solidipes

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.856AlaAla: 6.856 ± 0.041	1.148AlaCys: 1.148 ± 0.013	3.815AlaAsp: 3.815 ± 0.021	4.252AlaGlu: 4.252 ± 0.031	3.246AlaPhe: 3.246 ± 0.023	4.756AlaGly: 4.756 ± 0.03	1.795AlaHis: 1.795 ± 0.016	4.157AlaIle: 4.157 ± 0.021	3.477AlaLys: 3.477 ± 0.025	7.856AlaLeu: 7.856 ± 0.036	1.873AlaMet: 1.873 ± 0.016	2.609AlaAsn: 2.609 ± 0.019	4.389AlaPro: 4.389 ± 0.034	2.779AlaGln: 2.779 ± 0.02	4.41AlaArg: 4.41 ± 0.024	6.892AlaSer: 6.892 ± 0.033	4.808AlaThr: 4.808 ± 0.028	5.175AlaVal: 5.175 ± 0.031	1.226AlaTrp: 1.226 ± 0.013	2.221AlaTyr: 2.221 ± 0.017	0.0AlaXaa: 0.0 ± 0.0
Cys	1.035CysAla: 1.035 ± 0.012	0.319CysCys: 0.319 ± 0.007	0.773CysAsp: 0.773 ± 0.011	0.641CysGlu: 0.641 ± 0.009	0.645CysPhe: 0.645 ± 0.01	0.977CysGly: 0.977 ± 0.011	0.453CysHis: 0.453 ± 0.008	0.892CysIle: 0.892 ± 0.011	0.574CysLys: 0.574 ± 0.009	1.579CysLeu: 1.579 ± 0.017	0.357CysMet: 0.357 ± 0.007	0.485CysAsn: 0.485 ± 0.008	0.924CysPro: 0.924 ± 0.013	0.529CysGln: 0.529 ± 0.009	0.958CysArg: 0.958 ± 0.011	1.277CysSer: 1.277 ± 0.014	0.899CysThr: 0.899 ± 0.011	0.907CysVal: 0.907 ± 0.011	0.286CysTrp: 0.286 ± 0.007	0.429CysTyr: 0.429 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.569AspAla: 4.569 ± 0.026	0.721AspCys: 0.721 ± 0.011	4.311AspAsp: 4.311 ± 0.038	4.078AspGlu: 4.078 ± 0.031	2.216AspPhe: 2.216 ± 0.018	3.855AspGly: 3.855 ± 0.022	1.297AspHis: 1.297 ± 0.012	3.568AspIle: 3.568 ± 0.026	2.142AspLys: 2.142 ± 0.019	5.204AspLeu: 5.204 ± 0.028	1.28AspMet: 1.28 ± 0.013	1.861AspAsn: 1.861 ± 0.018	3.257AspPro: 3.257 ± 0.02	1.576AspGln: 1.576 ± 0.014	2.862AspArg: 2.862 ± 0.02	4.247AspSer: 4.247 ± 0.028	3.099AspThr: 3.099 ± 0.019	4.175AspVal: 4.175 ± 0.03	0.924AspTrp: 0.924 ± 0.01	1.626AspTyr: 1.626 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	4.469GluAla: 4.469 ± 0.029	0.73GluCys: 0.73 ± 0.011	3.981GluAsp: 3.981 ± 0.029	4.948GluGlu: 4.948 ± 0.042	1.846GluPhe: 1.846 ± 0.012	3.473GluGly: 3.473 ± 0.022	1.401GluHis: 1.401 ± 0.013	2.935GluIle: 2.935 ± 0.022	3.06GluLys: 3.06 ± 0.024	5.044GluLeu: 5.044 ± 0.03	1.418GluMet: 1.418 ± 0.012	1.941GluAsn: 1.941 ± 0.017	2.542GluPro: 2.542 ± 0.02	2.015GluGln: 2.015 ± 0.018	3.637GluArg: 3.637 ± 0.026	4.073GluSer: 4.073 ± 0.026	3.123GluThr: 3.123 ± 0.021	3.469GluVal: 3.469 ± 0.024	0.99GluTrp: 0.99 ± 0.012	1.654GluTyr: 1.654 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.011PheAla: 3.011 ± 0.022	0.656PheCys: 0.656 ± 0.01	2.348PheAsp: 2.348 ± 0.018	2.02PheGlu: 2.02 ± 0.016	1.77PhePhe: 1.77 ± 0.017	2.705PheGly: 2.705 ± 0.024	1.067PheHis: 1.067 ± 0.013	2.123PheIle: 2.123 ± 0.02	1.553PheLys: 1.553 ± 0.016	3.891PheLeu: 3.891 ± 0.028	0.819PheMet: 0.819 ± 0.01	1.443PheAsn: 1.443 ± 0.013	2.286PhePro: 2.286 ± 0.019	1.342PheGln: 1.342 ± 0.014	2.167PheArg: 2.167 ± 0.019	3.486PheSer: 3.486 ± 0.021	2.334PheThr: 2.334 ± 0.017	2.662PheVal: 2.662 ± 0.021	0.653PheTrp: 0.653 ± 0.008	1.18PheTyr: 1.18 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.402GlyAla: 4.402 ± 0.03	0.963GlyCys: 0.963 ± 0.012	3.323GlyAsp: 3.323 ± 0.024	3.123GlyGlu: 3.123 ± 0.02	2.486GlyPhe: 2.486 ± 0.02	4.731GlyGly: 4.731 ± 0.04	1.649GlyHis: 1.649 ± 0.016	3.513GlyIle: 3.513 ± 0.026	3.066GlyLys: 3.066 ± 0.026	5.542GlyLeu: 5.542 ± 0.027	1.48GlyMet: 1.48 ± 0.014	2.255GlyAsn: 2.255 ± 0.018	3.079GlyPro: 3.079 ± 0.022	2.091GlyGln: 2.091 ± 0.018	3.829GlyArg: 3.829 ± 0.024	5.285GlySer: 5.285 ± 0.032	3.851GlyThr: 3.851 ± 0.025	4.143GlyVal: 4.143 ± 0.025	1.136GlyTrp: 1.136 ± 0.013	1.972GlyTyr: 1.972 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.91HisAla: 1.91 ± 0.017	0.451HisCys: 0.451 ± 0.008	1.366HisAsp: 1.366 ± 0.013	1.249HisGlu: 1.249 ± 0.013	1.102HisPhe: 1.102 ± 0.013	1.604HisGly: 1.604 ± 0.015	0.897HisHis: 0.897 ± 0.011	1.474HisIle: 1.474 ± 0.016	0.939HisLys: 0.939 ± 0.012	2.699HisLeu: 2.699 ± 0.023	0.495HisMet: 0.495 ± 0.008	0.813HisAsn: 0.813 ± 0.011	1.851HisPro: 1.851 ± 0.016	0.932HisGln: 0.932 ± 0.011	1.742HisArg: 1.742 ± 0.017	2.162HisSer: 2.162 ± 0.02	1.466HisThr: 1.466 ± 0.016	1.656HisVal: 1.656 ± 0.014	0.377HisTrp: 0.377 ± 0.007	0.743HisTyr: 0.743 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.124IleAla: 4.124 ± 0.026	0.881IleCys: 0.881 ± 0.012	2.996IleAsp: 2.996 ± 0.02	2.766IleGlu: 2.766 ± 0.019	2.278IlePhe: 2.278 ± 0.019	3.049IleGly: 3.049 ± 0.024	1.431IleHis: 1.431 ± 0.014	2.967IleIle: 2.967 ± 0.023	2.112IleLys: 2.112 ± 0.019	5.283IleLeu: 5.283 ± 0.033	1.074IleMet: 1.074 ± 0.012	1.803IleAsn: 1.803 ± 0.015	3.568IlePro: 3.568 ± 0.021	1.92IleGln: 1.92 ± 0.014	3.069IleArg: 3.069 ± 0.021	4.554IleSer: 4.554 ± 0.027	3.149IleThr: 3.149 ± 0.022	3.536IleVal: 3.536 ± 0.022	0.828IleTrp: 0.828 ± 0.01	1.567IleTyr: 1.567 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.748LysAla: 3.748 ± 0.029	0.58LysCys: 0.58 ± 0.008	2.676LysAsp: 2.676 ± 0.023	3.051LysGlu: 3.051 ± 0.026	1.404LysPhe: 1.404 ± 0.013	2.785LysGly: 2.785 ± 0.022	1.118LysHis: 1.118 ± 0.013	2.132LysIle: 2.132 ± 0.018	2.88LysLys: 2.88 ± 0.031	3.818LysLeu: 3.818 ± 0.022	0.995LysMet: 0.995 ± 0.013	1.548LysAsn: 1.548 ± 0.015	2.323LysPro: 2.323 ± 0.019	1.566LysGln: 1.566 ± 0.016	3.225LysArg: 3.225 ± 0.026	3.2LysSer: 3.2 ± 0.024	2.611LysThr: 2.611 ± 0.019	2.756LysVal: 2.756 ± 0.019	0.688LysTrp: 0.688 ± 0.01	1.338LysTyr: 1.338 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.476LeuAla: 7.476 ± 0.034	1.595LeuCys: 1.595 ± 0.014	5.436LeuAsp: 5.436 ± 0.028	5.401LeuGlu: 5.401 ± 0.031	3.738LeuPhe: 3.738 ± 0.026	5.575LeuGly: 5.575 ± 0.034	2.689LeuHis: 2.689 ± 0.023	4.362LeuIle: 4.362 ± 0.025	4.217LeuLys: 4.217 ± 0.03	9.159LeuLeu: 9.159 ± 0.045	1.882LeuMet: 1.882 ± 0.015	3.242LeuAsn: 3.242 ± 0.022	6.304LeuPro: 6.304 ± 0.035	3.807LeuGln: 3.807 ± 0.022	6.212LeuArg: 6.212 ± 0.032	8.604LeuSer: 8.604 ± 0.044	5.442LeuThr: 5.442 ± 0.028	6.022LeuVal: 6.022 ± 0.03	1.421LeuTrp: 1.421 ± 0.014	2.701LeuTyr: 2.701 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	1.885MetAla: 1.885 ± 0.015	0.296MetCys: 0.296 ± 0.006	1.302MetAsp: 1.302 ± 0.013	1.246MetGlu: 1.246 ± 0.013	0.845MetPhe: 0.845 ± 0.011	1.271MetGly: 1.271 ± 0.014	0.563MetHis: 0.563 ± 0.008	1.07MetIle: 1.07 ± 0.012	1.058MetLys: 1.058 ± 0.012	1.985MetLeu: 1.985 ± 0.014	0.545MetMet: 0.545 ± 0.008	0.852MetAsn: 0.852 ± 0.011	1.272MetPro: 1.272 ± 0.013	0.83MetGln: 0.83 ± 0.01	1.256MetArg: 1.256 ± 0.012	2.154MetSer: 2.154 ± 0.016	1.384MetThr: 1.384 ± 0.015	1.336MetVal: 1.336 ± 0.012	0.289MetTrp: 0.289 ± 0.005	0.62MetTyr: 0.62 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.857AsnAla: 2.857 ± 0.02	0.463AsnCys: 0.463 ± 0.008	1.998AsnAsp: 1.998 ± 0.014	1.812AsnGlu: 1.812 ± 0.018	1.317AsnPhe: 1.317 ± 0.013	2.619AsnGly: 2.619 ± 0.02	0.859AsnHis: 0.859 ± 0.011	2.13AsnIle: 2.13 ± 0.02	1.315AsnLys: 1.315 ± 0.014	3.296AsnLeu: 3.296 ± 0.02	0.784AsnMet: 0.784 ± 0.011	1.287AsnAsn: 1.287 ± 0.016	2.23AsnPro: 2.23 ± 0.018	1.122AsnGln: 1.122 ± 0.013	1.806AsnArg: 1.806 ± 0.017	2.675AsnSer: 2.675 ± 0.022	2.157AsnThr: 2.157 ± 0.016	2.494AsnVal: 2.494 ± 0.018	0.541AsnTrp: 0.541 ± 0.01	0.971AsnTyr: 0.971 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	4.569ProAla: 4.569 ± 0.033	0.662ProCys: 0.662 ± 0.01	3.231ProAsp: 3.231 ± 0.022	3.454ProGlu: 3.454 ± 0.023	2.299ProPhe: 2.299 ± 0.017	3.455ProGly: 3.455 ± 0.021	1.486ProHis: 1.486 ± 0.016	2.928ProIle: 2.928 ± 0.02	2.468ProLys: 2.468 ± 0.021	5.306ProLeu: 5.306 ± 0.029	1.128ProMet: 1.128 ± 0.012	2.107ProAsn: 2.107 ± 0.017	5.668ProPro: 5.668 ± 0.063	2.127ProGln: 2.127 ± 0.021	3.427ProArg: 3.427 ± 0.024	6.862ProSer: 6.862 ± 0.043	4.109ProThr: 4.109 ± 0.027	3.872ProVal: 3.872 ± 0.028	0.854ProTrp: 0.854 ± 0.012	1.605ProTyr: 1.605 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	2.88GlnAla: 2.88 ± 0.016	0.588GlnCys: 0.588 ± 0.01	1.88GlnAsp: 1.88 ± 0.013	2.109GlnGlu: 2.109 ± 0.017	1.242GlnPhe: 1.242 ± 0.014	2.024GlnGly: 2.024 ± 0.016	0.957GlnHis: 0.957 ± 0.011	1.779GlnIle: 1.779 ± 0.015	1.591GlnLys: 1.591 ± 0.017	3.281GlnLeu: 3.281 ± 0.022	0.829GlnMet: 0.829 ± 0.01	1.308GlnAsn: 1.308 ± 0.013	2.038GlnPro: 2.038 ± 0.02	1.623GlnGln: 1.623 ± 0.025	2.402GlnArg: 2.402 ± 0.02	2.96GlnSer: 2.96 ± 0.021	2.189GlnThr: 2.189 ± 0.019	2.123GlnVal: 2.123 ± 0.018	0.612GlnTrp: 0.612 ± 0.01	1.124GlnTyr: 1.124 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.406ArgAla: 4.406 ± 0.029	1.009ArgCys: 1.009 ± 0.012	3.232ArgAsp: 3.232 ± 0.024	3.423ArgGlu: 3.423 ± 0.027	2.272ArgPhe: 2.272 ± 0.018	3.376ArgGly: 3.376 ± 0.026	1.678ArgHis: 1.678 ± 0.015	3.192ArgIle: 3.192 ± 0.019	3.181ArgLys: 3.181 ± 0.023	5.815ArgLeu: 5.815 ± 0.032	1.395ArgMet: 1.395 ± 0.014	2.133ArgAsn: 2.133 ± 0.018	3.399ArgPro: 3.399 ± 0.023	2.325ArgGln: 2.325 ± 0.018	5.166ArgArg: 5.166 ± 0.036	5.031ArgSer: 5.031 ± 0.035	3.484ArgThr: 3.484 ± 0.022	3.705ArgVal: 3.705 ± 0.024	1.017ArgTrp: 1.017 ± 0.011	1.795ArgTyr: 1.795 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.345SerAla: 6.345 ± 0.035	1.177SerCys: 1.177 ± 0.013	4.606SerAsp: 4.606 ± 0.029	4.102SerGlu: 4.102 ± 0.026	3.54SerPhe: 3.54 ± 0.023	5.282SerGly: 5.282 ± 0.034	2.225SerHis: 2.225 ± 0.02	4.481SerIle: 4.481 ± 0.024	3.499SerLys: 3.499 ± 0.026	8.68SerLeu: 8.68 ± 0.045	1.885SerMet: 1.885 ± 0.014	2.99SerAsn: 2.99 ± 0.023	5.913SerPro: 5.913 ± 0.045	3.068SerGln: 3.068 ± 0.02	5.199SerArg: 5.199 ± 0.034	10.095SerSer: 10.095 ± 0.072	5.998SerThr: 5.998 ± 0.04	5.385SerVal: 5.385 ± 0.031	1.272SerTrp: 1.272 ± 0.014	2.294SerTyr: 2.294 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	4.795ThrAla: 4.795 ± 0.028	0.901ThrCys: 0.901 ± 0.013	2.95ThrAsp: 2.95 ± 0.022	2.928ThrGlu: 2.928 ± 0.019	2.597ThrPhe: 2.597 ± 0.018	3.734ThrGly: 3.734 ± 0.025	1.44ThrHis: 1.44 ± 0.015	3.432ThrIle: 3.432 ± 0.022	2.45ThrLys: 2.45 ± 0.021	6.081ThrLeu: 6.081 ± 0.03	1.314ThrMet: 1.314 ± 0.014	2.031ThrAsn: 2.031 ± 0.016	4.235ThrPro: 4.235 ± 0.027	1.943ThrGln: 1.943 ± 0.018	3.317ThrArg: 3.317 ± 0.02	5.844ThrSer: 5.844 ± 0.037	4.197ThrThr: 4.197 ± 0.032	4.107ThrVal: 4.107 ± 0.027	0.882ThrTrp: 0.882 ± 0.012	1.685ThrTyr: 1.685 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	5.078ValAla: 5.078 ± 0.031	1.031ValCys: 1.031 ± 0.012	3.946ValAsp: 3.946 ± 0.02	3.816ValGlu: 3.816 ± 0.025	2.763ValPhe: 2.763 ± 0.022	3.818ValGly: 3.818 ± 0.026	1.667ValHis: 1.667 ± 0.015	3.343ValIle: 3.343 ± 0.022	2.862ValLys: 2.862 ± 0.021	6.492ValLeu: 6.492 ± 0.034	1.431ValMet: 1.431 ± 0.012	2.257ValAsn: 2.257 ± 0.019	4.011ValPro: 4.011 ± 0.024	2.408ValGln: 2.408 ± 0.02	3.454ValArg: 3.454 ± 0.021	5.14ValSer: 5.14 ± 0.03	3.701ValThr: 3.701 ± 0.025	4.761ValVal: 4.761 ± 0.028	1.024ValTrp: 1.024 ± 0.012	2.007ValTyr: 2.007 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.111TrpAla: 1.111 ± 0.013	0.29TrpCys: 0.29 ± 0.006	0.945TrpAsp: 0.945 ± 0.011	0.867TrpGlu: 0.867 ± 0.011	0.634TrpPhe: 0.634 ± 0.01	0.899TrpGly: 0.899 ± 0.012	0.39TrpHis: 0.39 ± 0.007	0.877TrpIle: 0.877 ± 0.01	0.901TrpLys: 0.901 ± 0.011	1.409TrpLeu: 1.409 ± 0.014	0.44TrpMet: 0.44 ± 0.007	0.674TrpAsn: 0.674 ± 0.009	0.642TrpPro: 0.642 ± 0.01	0.524TrpGln: 0.524 ± 0.009	1.151TrpArg: 1.151 ± 0.013	1.215TrpSer: 1.215 ± 0.014	1.068TrpThr: 1.068 ± 0.012	0.943TrpVal: 0.943 ± 0.01	0.329TrpTrp: 0.329 ± 0.007	0.486TrpTyr: 0.486 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.215TyrAla: 2.215 ± 0.013	0.479TyrCys: 0.479 ± 0.008	1.754TyrAsp: 1.754 ± 0.017	1.463TyrGlu: 1.463 ± 0.015	1.276TyrPhe: 1.276 ± 0.014	1.934TyrGly: 1.934 ± 0.017	0.867TyrHis: 0.867 ± 0.011	1.597TyrIle: 1.597 ± 0.014	1.095TyrLys: 1.095 ± 0.012	2.861TyrLeu: 2.861 ± 0.021	0.637TyrMet: 0.637 ± 0.01	1.091TyrAsn: 1.091 ± 0.011	1.688TyrPro: 1.688 ± 0.017	1.011TyrGln: 1.011 ± 0.012	1.746TyrArg: 1.746 ± 0.016	2.279TyrSer: 2.279 ± 0.018	1.791TyrThr: 1.791 ± 0.019	1.784TyrVal: 1.784 ± 0.018	0.447TyrTrp: 0.447 ± 0.008	0.973TyrTyr: 0.973 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 20715 proteins (7685379 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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