Amino acid dipepetide frequency for Tomato associated geminivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.031AlaAla: 1.031 ± 1.1
2.062AlaCys: 2.062 ± 0.775
11.34AlaAsp: 11.34 ± 2.493
4.124AlaGlu: 4.124 ± 1.069
0.0AlaPhe: 0.0 ± 0.0
3.093AlaGly: 3.093 ± 2.657
0.0AlaHis: 0.0 ± 0.0
5.155AlaIle: 5.155 ± 1.83
0.0AlaLys: 0.0 ± 0.0
3.093AlaLeu: 3.093 ± 1.593
2.062AlaMet: 2.062 ± 1.771
5.155AlaAsn: 5.155 ± 1.499
0.0AlaPro: 0.0 ± 0.0
1.031AlaGln: 1.031 ± 0.726
3.093AlaArg: 3.093 ± 1.172
4.124AlaSer: 4.124 ± 1.624
1.031AlaThr: 1.031 ± 0.886
4.124AlaVal: 4.124 ± 2.793
2.062AlaTrp: 2.062 ± 0.775
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.031CysAla: 1.031 ± 1.358
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.031CysGlu: 1.031 ± 0.726
0.0CysPhe: 0.0 ± 0.0
2.062CysGly: 2.062 ± 1.451
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.031CysLys: 1.031 ± 0.726
2.062CysLeu: 2.062 ± 0.775
0.0CysMet: 0.0 ± 0.0
2.062CysAsn: 2.062 ± 0.865
2.062CysPro: 2.062 ± 0.775
0.0CysGln: 0.0 ± 0.0
2.062CysArg: 2.062 ± 0.865
0.0CysSer: 0.0 ± 0.0
3.093CysThr: 3.093 ± 1.124
1.031CysVal: 1.031 ± 0.843
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.155AspAla: 5.155 ± 0.941
0.0AspCys: 0.0 ± 0.0
2.062AspAsp: 2.062 ± 0.865
0.0AspGlu: 0.0 ± 0.0
4.124AspPhe: 4.124 ± 1.55
2.062AspGly: 2.062 ± 0.775
0.0AspHis: 0.0 ± 0.0
7.216AspIle: 7.216 ± 1.561
3.093AspLys: 3.093 ± 0.484
2.062AspLeu: 2.062 ± 1.341
1.031AspMet: 1.031 ± 0.886
2.062AspAsn: 2.062 ± 0.865
3.093AspPro: 3.093 ± 1.448
3.093AspGln: 3.093 ± 1.242
2.062AspArg: 2.062 ± 1.456
2.062AspSer: 2.062 ± 1.771
1.031AspThr: 1.031 ± 0.843
3.093AspVal: 3.093 ± 1.416
1.031AspTrp: 1.031 ± 0.726
8.247AspTyr: 8.247 ± 1.723
0.0AspXaa: 0.0 ± 0.0
Glu
1.031GluAla: 1.031 ± 0.843
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
2.062GluGlu: 2.062 ± 0.775
0.0GluPhe: 0.0 ± 0.0
4.124GluGly: 4.124 ± 2.102
0.0GluHis: 0.0 ± 0.0
2.062GluIle: 2.062 ± 0.775
3.093GluLys: 3.093 ± 1.242
3.093GluLeu: 3.093 ± 1.43
0.0GluMet: 0.0 ± 0.0
3.093GluAsn: 3.093 ± 1.448
3.093GluPro: 3.093 ± 1.242
3.093GluGln: 3.093 ± 1.416
5.155GluArg: 5.155 ± 1.914
8.247GluSer: 8.247 ± 2.284
4.124GluThr: 4.124 ± 0.86
2.062GluVal: 2.062 ± 1.747
3.093GluTrp: 3.093 ± 1.172
4.124GluTyr: 4.124 ± 0.784
0.0GluXaa: 0.0 ± 0.0
Phe
1.031PheAla: 1.031 ± 0.886
1.031PheCys: 1.031 ± 0.886
4.124PheAsp: 4.124 ± 1.55
2.062PheGlu: 2.062 ± 0.775
7.216PhePhe: 7.216 ± 2.679
1.031PheGly: 1.031 ± 0.886
0.0PheHis: 0.0 ± 0.0
5.155PheIle: 5.155 ± 1.939
2.062PheLys: 2.062 ± 0.775
7.216PheLeu: 7.216 ± 2.042
0.0PheMet: 0.0 ± 0.0
3.093PheAsn: 3.093 ± 2.304
0.0PhePro: 0.0 ± 0.0
6.186PheGln: 6.186 ± 1.297
0.0PheArg: 0.0 ± 0.0
4.124PheSer: 4.124 ± 2.451
1.031PheThr: 1.031 ± 0.726
4.124PheVal: 4.124 ± 1.857
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.216GlyAla: 7.216 ± 3.682
0.0GlyCys: 0.0 ± 0.0
1.031GlyAsp: 1.031 ± 0.886
2.062GlyGlu: 2.062 ± 0.775
1.031GlyPhe: 1.031 ± 0.886
5.155GlyGly: 5.155 ± 1.431
0.0GlyHis: 0.0 ± 0.0
9.278GlyIle: 9.278 ± 1.983
5.155GlyLys: 5.155 ± 1.431
2.062GlyLeu: 2.062 ± 1.771
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
2.062GlyPro: 2.062 ± 0.865
0.0GlyGln: 0.0 ± 0.0
0.0GlyArg: 0.0 ± 0.0
4.124GlySer: 4.124 ± 0.86
2.062GlyThr: 2.062 ± 0.775
4.124GlyVal: 4.124 ± 1.634
0.0GlyTrp: 0.0 ± 0.0
2.062GlyTyr: 2.062 ± 1.355
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
2.062HisCys: 2.062 ± 0.775
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
3.093HisIle: 3.093 ± 1.448
0.0HisLys: 0.0 ± 0.0
1.031HisLeu: 1.031 ± 0.886
0.0HisMet: 0.0 ± 0.0
3.093HisAsn: 3.093 ± 1.593
2.062HisPro: 2.062 ± 0.775
2.062HisGln: 2.062 ± 0.775
1.031HisArg: 1.031 ± 0.886
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
2.062HisTrp: 2.062 ± 0.775
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.031IleAla: 1.031 ± 0.886
1.031IleCys: 1.031 ± 1.1
3.093IleAsp: 3.093 ± 1.416
3.093IleGlu: 3.093 ± 1.172
3.093IlePhe: 3.093 ± 0.484
3.093IleGly: 3.093 ± 1.124
2.062IleHis: 2.062 ± 0.775
6.186IleIle: 6.186 ± 2.362
1.031IleLys: 1.031 ± 0.726
8.247IleLeu: 8.247 ± 1.567
0.0IleMet: 0.0 ± 0.0
2.062IleAsn: 2.062 ± 0.775
9.278IlePro: 9.278 ± 3.169
5.155IleGln: 5.155 ± 1.939
2.062IleArg: 2.062 ± 1.341
6.186IleSer: 6.186 ± 2.577
3.093IleThr: 3.093 ± 0.484
2.062IleVal: 2.062 ± 1.355
2.062IleTrp: 2.062 ± 0.775
3.093IleTyr: 3.093 ± 1.242
0.0IleXaa: 0.0 ± 0.0
Lys
1.031LysAla: 1.031 ± 0.886
4.124LysCys: 4.124 ± 0.784
3.093LysAsp: 3.093 ± 1.242
2.062LysGlu: 2.062 ± 1.456
1.031LysPhe: 1.031 ± 0.886
4.124LysGly: 4.124 ± 1.643
1.031LysHis: 1.031 ± 0.726
2.062LysIle: 2.062 ± 0.775
6.186LysLys: 6.186 ± 2.129
2.062LysLeu: 2.062 ± 1.526
3.093LysMet: 3.093 ± 1.635
3.093LysAsn: 3.093 ± 1.242
0.0LysPro: 0.0 ± 0.0
3.093LysGln: 3.093 ± 0.484
6.186LysArg: 6.186 ± 2.924
4.124LysSer: 4.124 ± 1.55
1.031LysThr: 1.031 ± 0.726
2.062LysVal: 2.062 ± 1.526
0.0LysTrp: 0.0 ± 0.0
2.062LysTyr: 2.062 ± 0.865
0.0LysXaa: 0.0 ± 0.0
Leu
4.124LeuAla: 4.124 ± 0.86
1.031LeuCys: 1.031 ± 0.726
1.031LeuAsp: 1.031 ± 1.358
5.155LeuGlu: 5.155 ± 1.499
1.031LeuPhe: 1.031 ± 1.1
3.093LeuGly: 3.093 ± 1.328
1.031LeuHis: 1.031 ± 0.843
3.093LeuIle: 3.093 ± 1.416
4.124LeuLys: 4.124 ± 1.159
3.093LeuLeu: 3.093 ± 1.416
0.0LeuMet: 0.0 ± 0.0
1.031LeuAsn: 1.031 ± 0.886
3.093LeuPro: 3.093 ± 1.593
5.155LeuGln: 5.155 ± 2.785
5.155LeuArg: 5.155 ± 1.336
4.124LeuSer: 4.124 ± 1.633
6.186LeuThr: 6.186 ± 0.968
5.155LeuVal: 5.155 ± 1.586
0.0LeuTrp: 0.0 ± 0.0
7.216LeuTyr: 7.216 ± 1.561
0.0LeuXaa: 0.0 ± 0.0
Met
3.093MetAla: 3.093 ± 0.484
0.0MetCys: 0.0 ± 0.0
1.031MetAsp: 1.031 ± 1.358
3.093MetGlu: 3.093 ± 1.356
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
1.031MetMet: 1.031 ± 0.886
1.031MetAsn: 1.031 ± 0.886
4.124MetPro: 4.124 ± 1.199
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.031MetSer: 1.031 ± 0.886
1.031MetThr: 1.031 ± 0.886
1.031MetVal: 1.031 ± 0.886
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.031AsnAla: 1.031 ± 1.1
0.0AsnCys: 0.0 ± 0.0
1.031AsnAsp: 1.031 ± 1.358
1.031AsnGlu: 1.031 ± 0.726
4.124AsnPhe: 4.124 ± 2.084
3.093AsnGly: 3.093 ± 1.124
3.093AsnHis: 3.093 ± 0.484
3.093AsnIle: 3.093 ± 0.484
1.031AsnLys: 1.031 ± 0.726
5.155AsnLeu: 5.155 ± 1.939
0.0AsnMet: 0.0 ± 0.0
3.093AsnAsn: 3.093 ± 0.484
2.062AsnPro: 2.062 ± 0.953
6.186AsnGln: 6.186 ± 2.05
5.155AsnArg: 5.155 ± 1.359
7.216AsnSer: 7.216 ± 4.011
3.093AsnThr: 3.093 ± 1.593
6.186AsnVal: 6.186 ± 1.457
1.031AsnTrp: 1.031 ± 0.843
4.124AsnTyr: 4.124 ± 1.881
0.0AsnXaa: 0.0 ± 0.0
Pro
1.031ProAla: 1.031 ± 0.886
1.031ProCys: 1.031 ± 0.726
1.031ProAsp: 1.031 ± 0.726
6.186ProGlu: 6.186 ± 1.857
1.031ProPhe: 1.031 ± 0.726
2.062ProGly: 2.062 ± 1.526
2.062ProHis: 2.062 ± 0.775
4.124ProIle: 4.124 ± 1.199
5.155ProLys: 5.155 ± 0.941
3.093ProLeu: 3.093 ± 1.416
0.0ProMet: 0.0 ± 0.0
4.124ProAsn: 4.124 ± 1.55
5.155ProPro: 5.155 ± 1.863
1.031ProGln: 1.031 ± 0.843
8.247ProArg: 8.247 ± 1.466
4.124ProSer: 4.124 ± 1.55
7.216ProThr: 7.216 ± 1.082
2.062ProVal: 2.062 ± 1.355
0.0ProTrp: 0.0 ± 0.0
2.062ProTyr: 2.062 ± 0.775
0.0ProXaa: 0.0 ± 0.0
Gln
1.031GlnAla: 1.031 ± 0.843
0.0GlnCys: 0.0 ± 0.0
4.124GlnAsp: 4.124 ± 1.199
1.031GlnGlu: 1.031 ± 1.1
2.062GlnPhe: 2.062 ± 1.456
3.093GlnGly: 3.093 ± 0.484
2.062GlnHis: 2.062 ± 0.775
2.062GlnIle: 2.062 ± 0.775
1.031GlnLys: 1.031 ± 0.726
6.186GlnLeu: 6.186 ± 3.823
1.031GlnMet: 1.031 ± 1.269
7.216GlnAsn: 7.216 ± 2.679
6.186GlnPro: 6.186 ± 2.325
1.031GlnGln: 1.031 ± 0.726
3.093GlnArg: 3.093 ± 0.484
3.093GlnSer: 3.093 ± 2.124
7.216GlnThr: 7.216 ± 1.749
1.031GlnVal: 1.031 ± 0.886
2.062GlnTrp: 2.062 ± 0.775
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.155ArgAla: 5.155 ± 0.941
1.031ArgCys: 1.031 ± 0.726
5.155ArgAsp: 5.155 ± 0.941
2.062ArgGlu: 2.062 ± 1.341
6.186ArgPhe: 6.186 ± 0.968
5.155ArgGly: 5.155 ± 1.336
0.0ArgHis: 0.0 ± 0.0
3.093ArgIle: 3.093 ± 1.242
5.155ArgLys: 5.155 ± 3.634
3.093ArgLeu: 3.093 ± 2.584
0.0ArgMet: 0.0 ± 0.0
5.155ArgAsn: 5.155 ± 1.235
3.093ArgPro: 3.093 ± 1.172
3.093ArgGln: 3.093 ± 1.124
8.247ArgArg: 8.247 ± 1.72
5.155ArgSer: 5.155 ± 0.833
1.031ArgThr: 1.031 ± 0.886
4.124ArgVal: 4.124 ± 1.199
2.062ArgTrp: 2.062 ± 0.775
1.031ArgTyr: 1.031 ± 0.886
0.0ArgXaa: 0.0 ± 0.0
Ser
2.062SerAla: 2.062 ± 1.771
0.0SerCys: 0.0 ± 0.0
6.186SerAsp: 6.186 ± 1.297
5.155SerGlu: 5.155 ± 2.366
7.216SerPhe: 7.216 ± 1.554
4.124SerGly: 4.124 ± 1.199
0.0SerHis: 0.0 ± 0.0
5.155SerIle: 5.155 ± 2.391
6.186SerLys: 6.186 ± 1.247
3.093SerLeu: 3.093 ± 1.242
2.062SerMet: 2.062 ± 1.771
3.093SerAsn: 3.093 ± 1.172
5.155SerPro: 5.155 ± 1.326
2.062SerGln: 2.062 ± 0.865
6.186SerArg: 6.186 ± 2.098
4.124SerSer: 4.124 ± 0.86
3.093SerThr: 3.093 ± 1.124
4.124SerVal: 4.124 ± 2.793
2.062SerTrp: 2.062 ± 1.526
4.124SerTyr: 4.124 ± 1.55
0.0SerXaa: 0.0 ± 0.0
Thr
6.186ThrAla: 6.186 ± 2.129
1.031ThrCys: 1.031 ± 1.358
4.124ThrAsp: 4.124 ± 1.624
4.124ThrGlu: 4.124 ± 1.55
3.093ThrPhe: 3.093 ± 0.484
2.062ThrGly: 2.062 ± 1.771
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
2.062ThrLys: 2.062 ± 0.953
4.124ThrLeu: 4.124 ± 2.711
0.0ThrMet: 0.0 ± 0.0
2.062ThrAsn: 2.062 ± 0.775
3.093ThrPro: 3.093 ± 1.124
2.062ThrGln: 2.062 ± 0.775
6.186ThrArg: 6.186 ± 1.297
5.155ThrSer: 5.155 ± 2.052
4.124ThrThr: 4.124 ± 1.199
2.062ThrVal: 2.062 ± 0.865
0.0ThrTrp: 0.0 ± 0.0
9.278ThrTyr: 9.278 ± 1.879
0.0ThrXaa: 0.0 ± 0.0
Val
2.062ValAla: 2.062 ± 0.775
0.0ValCys: 0.0 ± 0.0
2.062ValAsp: 2.062 ± 0.865
2.062ValGlu: 2.062 ± 0.865
3.093ValPhe: 3.093 ± 1.593
0.0ValGly: 0.0 ± 0.0
1.031ValHis: 1.031 ± 0.886
1.031ValIle: 1.031 ± 1.1
3.093ValLys: 3.093 ± 2.094
2.062ValLeu: 2.062 ± 0.775
2.062ValMet: 2.062 ± 1.167
5.155ValAsn: 5.155 ± 2.002
2.062ValPro: 2.062 ± 1.145
7.216ValGln: 7.216 ± 2.216
2.062ValArg: 2.062 ± 0.775
2.062ValSer: 2.062 ± 0.953
3.093ValThr: 3.093 ± 1.124
4.124ValVal: 4.124 ± 2.711
1.031ValTrp: 1.031 ± 0.843
9.278ValTyr: 9.278 ± 4.536
0.0ValXaa: 0.0 ± 0.0
Trp
5.155TrpAla: 5.155 ± 0.941
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.031TrpGlu: 1.031 ± 0.843
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.062TrpPro: 2.062 ± 0.775
1.031TrpGln: 1.031 ± 1.358
0.0TrpArg: 0.0 ± 0.0
4.124TrpSer: 4.124 ± 1.402
4.124TrpThr: 4.124 ± 1.55
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.031TrpTyr: 1.031 ± 0.843
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.093TyrAla: 3.093 ± 0.484
3.093TyrCys: 3.093 ± 1.242
2.062TyrAsp: 2.062 ± 0.865
4.124TyrGlu: 4.124 ± 1.677
5.155TyrPhe: 5.155 ± 0.941
0.0TyrGly: 0.0 ± 0.0
4.124TyrHis: 4.124 ± 1.199
5.155TyrIle: 5.155 ± 1.914
2.062TyrLys: 2.062 ± 0.865
3.093TyrLeu: 3.093 ± 1.635
3.093TyrMet: 3.093 ± 1.158
5.155TyrAsn: 5.155 ± 1.214
3.093TyrPro: 3.093 ± 1.416
3.093TyrGln: 3.093 ± 1.448
3.093TyrArg: 3.093 ± 1.448
2.062TyrSer: 2.062 ± 1.355
4.124TyrThr: 4.124 ± 1.199
2.062TyrVal: 2.062 ± 0.775
0.0TyrTrp: 0.0 ± 0.0
1.031TyrTyr: 1.031 ± 0.726
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (971 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski