Amino acid dipepetide frequency for Panicum hallii var. hallii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.699AlaAla: 14.699 ± 0.071	1.673AlaCys: 1.673 ± 0.013	4.368AlaAsp: 4.368 ± 0.017	5.23AlaGlu: 5.23 ± 0.021	2.985AlaPhe: 2.985 ± 0.017	7.186AlaGly: 7.186 ± 0.033	1.825AlaHis: 1.825 ± 0.012	3.539AlaIle: 3.539 ± 0.018	3.78AlaLys: 3.78 ± 0.018	8.208AlaLeu: 8.208 ± 0.025	2.218AlaMet: 2.218 ± 0.014	2.568AlaAsn: 2.568 ± 0.013	5.529AlaPro: 5.529 ± 0.028	2.643AlaGln: 2.643 ± 0.016	5.9AlaArg: 5.9 ± 0.027	7.761AlaSer: 7.761 ± 0.028	4.67AlaThr: 4.67 ± 0.019	6.733AlaVal: 6.733 ± 0.026	1.032AlaTrp: 1.032 ± 0.009	1.983AlaTyr: 1.983 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	1.444CysAla: 1.444 ± 0.011	0.624CysCys: 0.624 ± 0.008	0.888CysAsp: 0.888 ± 0.008	0.817CysGlu: 0.817 ± 0.007	0.816CysPhe: 0.816 ± 0.007	1.53CysGly: 1.53 ± 0.013	0.503CysHis: 0.503 ± 0.006	0.891CysIle: 0.891 ± 0.008	0.941CysLys: 0.941 ± 0.008	1.844CysLeu: 1.844 ± 0.013	0.462CysMet: 0.462 ± 0.005	0.699CysAsn: 0.699 ± 0.007	1.069CysPro: 1.069 ± 0.01	0.593CysGln: 0.593 ± 0.007	1.354CysArg: 1.354 ± 0.012	1.924CysSer: 1.924 ± 0.013	0.932CysThr: 0.932 ± 0.008	1.106CysVal: 1.106 ± 0.008	0.27CysTrp: 0.27 ± 0.004	0.521CysTyr: 0.521 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.963AspAla: 4.963 ± 0.02	0.894AspCys: 0.894 ± 0.009	3.96AspAsp: 3.96 ± 0.022	3.883AspGlu: 3.883 ± 0.018	1.958AspPhe: 1.958 ± 0.013	4.544AspGly: 4.544 ± 0.019	1.233AspHis: 1.233 ± 0.01	2.559AspIle: 2.559 ± 0.014	2.359AspLys: 2.359 ± 0.014	4.865AspLeu: 4.865 ± 0.019	1.345AspMet: 1.345 ± 0.01	1.718AspAsn: 1.718 ± 0.013	2.795AspPro: 2.795 ± 0.014	1.61AspGln: 1.61 ± 0.011	2.745AspArg: 2.745 ± 0.014	3.709AspSer: 3.709 ± 0.018	2.232AspThr: 2.232 ± 0.013	3.681AspVal: 3.681 ± 0.015	0.684AspTrp: 0.684 ± 0.007	1.354AspTyr: 1.354 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	5.575GluAla: 5.575 ± 0.023	0.877GluCys: 0.877 ± 0.009	3.691GluAsp: 3.691 ± 0.017	5.66GluGlu: 5.66 ± 0.033	1.961GluPhe: 1.961 ± 0.011	3.747GluGly: 3.747 ± 0.016	1.401GluHis: 1.401 ± 0.011	2.872GluIle: 2.872 ± 0.014	3.693GluLys: 3.693 ± 0.023	5.769GluLeu: 5.769 ± 0.027	1.62GluMet: 1.62 ± 0.011	2.215GluAsn: 2.215 ± 0.014	2.479GluPro: 2.479 ± 0.015	2.278GluGln: 2.278 ± 0.014	3.637GluArg: 3.637 ± 0.02	3.822GluSer: 3.822 ± 0.019	2.516GluThr: 2.516 ± 0.015	4.036GluVal: 4.036 ± 0.019	0.714GluTrp: 0.714 ± 0.008	1.481GluTyr: 1.481 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.808PheAla: 2.808 ± 0.016	0.79PheCys: 0.79 ± 0.007	2.083PheAsp: 2.083 ± 0.012	1.822PheGlu: 1.822 ± 0.011	1.65PhePhe: 1.65 ± 0.012	2.824PheGly: 2.824 ± 0.018	1.001PheHis: 1.001 ± 0.008	1.568PheIle: 1.568 ± 0.012	1.472PheLys: 1.472 ± 0.012	3.795PheLeu: 3.795 ± 0.019	0.845PheMet: 0.845 ± 0.008	1.257PheAsn: 1.257 ± 0.01	1.874PhePro: 1.874 ± 0.011	1.249PheGln: 1.249 ± 0.009	2.091PheArg: 2.091 ± 0.014	3.248PheSer: 3.248 ± 0.015	1.691PheThr: 1.691 ± 0.012	2.539PheVal: 2.539 ± 0.015	0.516PheTrp: 0.516 ± 0.006	1.042PheTyr: 1.042 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	6.757GlyAla: 6.757 ± 0.032	1.472GlyCys: 1.472 ± 0.012	3.987GlyAsp: 3.987 ± 0.016	3.907GlyGlu: 3.907 ± 0.02	2.834GlyPhe: 2.834 ± 0.017	7.935GlyGly: 7.935 ± 0.052	1.816GlyHis: 1.816 ± 0.012	3.051GlyIle: 3.051 ± 0.017	3.526GlyLys: 3.526 ± 0.017	5.98GlyLeu: 5.98 ± 0.024	1.637GlyMet: 1.637 ± 0.01	2.68GlyAsn: 2.68 ± 0.015	3.07GlyPro: 3.07 ± 0.019	2.216GlyGln: 2.216 ± 0.013	5.088GlyArg: 5.088 ± 0.023	6.346GlySer: 6.346 ± 0.025	3.567GlyThr: 3.567 ± 0.016	4.653GlyVal: 4.653 ± 0.021	1.008GlyTrp: 1.008 ± 0.008	2.053GlyTyr: 2.053 ± 0.014	0.0GlyXaa: 0.0 ± 0.0
His	1.985HisAla: 1.985 ± 0.012	0.552HisCys: 0.552 ± 0.007	1.236HisAsp: 1.236 ± 0.01	1.26HisGlu: 1.26 ± 0.009	0.914HisPhe: 0.914 ± 0.007	2.163HisGly: 2.163 ± 0.015	1.041HisHis: 1.041 ± 0.012	1.031HisIle: 1.031 ± 0.008	0.967HisLys: 0.967 ± 0.009	2.489HisLeu: 2.489 ± 0.014	0.569HisMet: 0.569 ± 0.006	0.771HisAsn: 0.771 ± 0.008	1.588HisPro: 1.588 ± 0.011	1.006HisGln: 1.006 ± 0.009	1.761HisArg: 1.761 ± 0.012	1.759HisSer: 1.759 ± 0.012	0.972HisThr: 0.972 ± 0.008	1.606HisVal: 1.606 ± 0.011	0.319HisTrp: 0.319 ± 0.005	0.652HisTyr: 0.652 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	3.449IleAla: 3.449 ± 0.018	0.943IleCys: 0.943 ± 0.008	2.384IleAsp: 2.384 ± 0.012	2.429IleGlu: 2.429 ± 0.013	1.699IlePhe: 1.699 ± 0.011	2.895IleGly: 2.895 ± 0.019	1.081IleHis: 1.081 ± 0.008	2.114IleIle: 2.114 ± 0.014	2.148IleLys: 2.148 ± 0.013	4.222IleLeu: 4.222 ± 0.02	0.959IleMet: 0.959 ± 0.009	1.597IleAsn: 1.597 ± 0.012	2.411IlePro: 2.411 ± 0.016	1.572IleGln: 1.572 ± 0.01	2.431IleArg: 2.431 ± 0.013	3.746IleSer: 3.746 ± 0.019	2.154IleThr: 2.154 ± 0.013	2.896IleVal: 2.896 ± 0.014	0.572IleTrp: 0.572 ± 0.006	1.2IleTyr: 1.2 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	3.832LysAla: 3.832 ± 0.018	0.785LysCys: 0.785 ± 0.008	2.709LysAsp: 2.709 ± 0.015	3.613LysGlu: 3.613 ± 0.022	1.559LysPhe: 1.559 ± 0.013	3.039LysGly: 3.039 ± 0.014	1.168LysHis: 1.168 ± 0.009	2.381LysIle: 2.381 ± 0.014	3.58LysLys: 3.58 ± 0.025	4.758LysLeu: 4.758 ± 0.022	1.229LysMet: 1.229 ± 0.008	1.914LysAsn: 1.914 ± 0.012	2.334LysPro: 2.334 ± 0.016	1.916LysGln: 1.916 ± 0.014	3.183LysArg: 3.183 ± 0.014	3.418LysSer: 3.418 ± 0.018	2.176LysThr: 2.176 ± 0.015	3.179LysVal: 3.179 ± 0.015	0.594LysTrp: 0.594 ± 0.005	1.3LysTyr: 1.3 ± 0.009	0.0LysXaa: 0.0 ± 0.0
Leu	8.34LeuAla: 8.34 ± 0.033	1.866LeuCys: 1.866 ± 0.013	4.966LeuAsp: 4.966 ± 0.019	5.686LeuGlu: 5.686 ± 0.027	3.358LeuPhe: 3.358 ± 0.015	6.004LeuGly: 6.004 ± 0.021	2.672LeuHis: 2.672 ± 0.013	3.603LeuIle: 3.603 ± 0.019	4.646LeuLys: 4.646 ± 0.021	10.571LeuLeu: 10.571 ± 0.038	2.006LeuMet: 2.006 ± 0.012	3.001LeuAsn: 3.001 ± 0.015	5.925LeuPro: 5.925 ± 0.026	4.143LeuGln: 4.143 ± 0.019	6.453LeuArg: 6.453 ± 0.029	7.722LeuSer: 7.722 ± 0.026	4.099LeuThr: 4.099 ± 0.019	6.463LeuVal: 6.463 ± 0.024	1.141LeuTrp: 1.141 ± 0.009	2.243LeuTyr: 2.243 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	2.64MetAla: 2.64 ± 0.014	0.344MetCys: 0.344 ± 0.005	1.429MetAsp: 1.429 ± 0.01	1.801MetGlu: 1.801 ± 0.011	0.753MetPhe: 0.753 ± 0.008	1.52MetGly: 1.52 ± 0.012	0.576MetHis: 0.576 ± 0.006	0.95MetIle: 0.95 ± 0.007	1.247MetLys: 1.247 ± 0.01	2.235MetLeu: 2.235 ± 0.012	0.65MetMet: 0.65 ± 0.008	0.805MetAsn: 0.805 ± 0.008	1.302MetPro: 1.302 ± 0.01	0.948MetGln: 0.948 ± 0.009	1.354MetArg: 1.354 ± 0.01	1.701MetSer: 1.701 ± 0.01	0.994MetThr: 0.994 ± 0.008	1.635MetVal: 1.635 ± 0.011	0.267MetTrp: 0.267 ± 0.004	0.564MetTyr: 0.564 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.613AsnAla: 2.613 ± 0.013	0.704AsnCys: 0.704 ± 0.007	1.663AsnAsp: 1.663 ± 0.011	1.86AsnGlu: 1.86 ± 0.013	1.376AsnPhe: 1.376 ± 0.01	2.786AsnGly: 2.786 ± 0.014	0.86AsnHis: 0.86 ± 0.009	1.898AsnIle: 1.898 ± 0.012	1.754AsnLys: 1.754 ± 0.012	3.529AsnLeu: 3.529 ± 0.023	0.938AsnMet: 0.938 ± 0.009	1.559AsnAsn: 1.559 ± 0.014	1.876AsnPro: 1.876 ± 0.013	1.273AsnGln: 1.273 ± 0.01	1.785AsnArg: 1.785 ± 0.011	2.816AsnSer: 2.816 ± 0.017	1.644AsnThr: 1.644 ± 0.012	2.229AsnVal: 2.229 ± 0.013	0.44AsnTrp: 0.44 ± 0.005	0.977AsnTyr: 0.977 ± 0.007	0.0AsnXaa: 0.0 ± 0.0
Pro	6.134ProAla: 6.134 ± 0.029	0.991ProCys: 0.991 ± 0.009	2.813ProAsp: 2.813 ± 0.015	3.341ProGlu: 3.341 ± 0.016	1.899ProPhe: 1.899 ± 0.011	3.743ProGly: 3.743 ± 0.022	1.306ProHis: 1.306 ± 0.01	1.894ProIle: 1.894 ± 0.011	2.285ProLys: 2.285 ± 0.016	4.67ProLeu: 4.67 ± 0.023	1.083ProMet: 1.083 ± 0.009	1.82ProAsn: 1.82 ± 0.012	6.141ProPro: 6.141 ± 0.045	1.932ProGln: 1.932 ± 0.015	3.78ProArg: 3.78 ± 0.021	5.634ProSer: 5.634 ± 0.026	2.817ProThr: 2.817 ± 0.015	3.579ProVal: 3.579 ± 0.017	0.719ProTrp: 0.719 ± 0.007	1.286ProTyr: 1.286 ± 0.01	0.0ProXaa: 0.0 ± 0.0
Gln	2.796GlnAla: 2.796 ± 0.014	0.614GlnCys: 0.614 ± 0.006	1.637GlnAsp: 1.637 ± 0.012	2.355GlnGlu: 2.355 ± 0.014	1.156GlnPhe: 1.156 ± 0.009	2.239GlnGly: 2.239 ± 0.013	1.01GlnHis: 1.01 ± 0.009	1.588GlnIle: 1.588 ± 0.01	1.901GlnLys: 1.901 ± 0.014	3.522GlnLeu: 3.522 ± 0.018	0.944GlnMet: 0.944 ± 0.01	1.358GlnAsn: 1.358 ± 0.01	2.068GlnPro: 2.068 ± 0.015	2.326GlnGln: 2.326 ± 0.029	2.355GlnArg: 2.355 ± 0.015	2.499GlnSer: 2.499 ± 0.016	1.463GlnThr: 1.463 ± 0.01	2.251GlnVal: 2.251 ± 0.013	0.467GlnTrp: 0.467 ± 0.006	0.885GlnTyr: 0.885 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	5.605ArgAla: 5.605 ± 0.024	1.325ArgCys: 1.325 ± 0.01	3.054ArgAsp: 3.054 ± 0.015	3.575ArgGlu: 3.575 ± 0.019	2.235ArgPhe: 2.235 ± 0.014	4.564ArgGly: 4.564 ± 0.025	1.736ArgHis: 1.736 ± 0.012	2.622ArgIle: 2.622 ± 0.013	3.381ArgLys: 3.381 ± 0.018	6.064ArgLeu: 6.064 ± 0.024	1.492ArgMet: 1.492 ± 0.011	2.176ArgAsn: 2.176 ± 0.013	3.67ArgPro: 3.67 ± 0.02	2.157ArgGln: 2.157 ± 0.013	6.814ArgArg: 6.814 ± 0.039	5.165ArgSer: 5.165 ± 0.023	2.773ArgThr: 2.773 ± 0.013	3.847ArgVal: 3.847 ± 0.018	1.011ArgTrp: 1.011 ± 0.009	1.564ArgTyr: 1.564 ± 0.011	0.0ArgXaa: 0.0 ± 0.0
Ser	6.895SerAla: 6.895 ± 0.025	1.774SerCys: 1.774 ± 0.013	4.079SerAsp: 4.079 ± 0.02	4.121SerGlu: 4.121 ± 0.023	3.257SerPhe: 3.257 ± 0.012	6.208SerGly: 6.208 ± 0.025	1.81SerHis: 1.81 ± 0.013	3.549SerIle: 3.549 ± 0.016	3.793SerLys: 3.793 ± 0.02	7.731SerLeu: 7.731 ± 0.027	2.012SerMet: 2.012 ± 0.012	3.026SerAsn: 3.026 ± 0.016	5.108SerPro: 5.108 ± 0.027	2.572SerGln: 2.572 ± 0.017	4.972SerArg: 4.972 ± 0.018	10.219SerSer: 10.219 ± 0.042	4.49SerThr: 4.49 ± 0.02	4.964SerVal: 4.964 ± 0.02	1.154SerTrp: 1.154 ± 0.01	2.068SerTyr: 2.068 ± 0.011	0.0SerXaa: 0.0 ± 0.0
Thr	4.408ThrAla: 4.408 ± 0.019	0.952ThrCys: 0.952 ± 0.008	2.274ThrAsp: 2.274 ± 0.013	2.565ThrGlu: 2.565 ± 0.016	1.739ThrPhe: 1.739 ± 0.011	3.525ThrGly: 3.525 ± 0.017	0.947ThrHis: 0.947 ± 0.008	2.183ThrIle: 2.183 ± 0.011	2.18ThrLys: 2.18 ± 0.013	4.184ThrLeu: 4.184 ± 0.02	1.177ThrMet: 1.177 ± 0.01	1.689ThrAsn: 1.689 ± 0.011	2.884ThrPro: 2.884 ± 0.018	1.345ThrGln: 1.345 ± 0.01	2.633ThrArg: 2.633 ± 0.014	4.323ThrSer: 4.323 ± 0.02	2.867ThrThr: 2.867 ± 0.016	3.428ThrVal: 3.428 ± 0.017	0.615ThrTrp: 0.615 ± 0.007	1.237ThrTyr: 1.237 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	6.656ValAla: 6.656 ± 0.024	1.183ValCys: 1.183 ± 0.009	3.782ValAsp: 3.782 ± 0.018	4.032ValGlu: 4.032 ± 0.02	2.435ValPhe: 2.435 ± 0.014	4.362ValGly: 4.362 ± 0.018	1.645ValHis: 1.645 ± 0.012	2.808ValIle: 2.808 ± 0.015	3.1ValLys: 3.1 ± 0.015	6.652ValLeu: 6.652 ± 0.026	1.482ValMet: 1.482 ± 0.01	2.088ValAsn: 2.088 ± 0.012	3.897ValPro: 3.897 ± 0.019	2.326ValGln: 2.326 ± 0.013	3.907ValArg: 3.907 ± 0.018	5.033ValSer: 5.033 ± 0.018	3.272ValThr: 3.272 ± 0.013	5.31ValVal: 5.31 ± 0.023	0.803ValTrp: 0.803 ± 0.008	1.746ValTyr: 1.746 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	0.982TrpAla: 0.982 ± 0.009	0.274TrpCys: 0.274 ± 0.004	0.682TrpAsp: 0.682 ± 0.007	0.736TrpGlu: 0.736 ± 0.008	0.496TrpPhe: 0.496 ± 0.006	0.749TrpGly: 0.749 ± 0.009	0.314TrpHis: 0.314 ± 0.004	0.58TrpIle: 0.58 ± 0.007	0.725TrpLys: 0.725 ± 0.007	1.281TrpLeu: 1.281 ± 0.011	0.354TrpMet: 0.354 ± 0.005	0.588TrpAsn: 0.588 ± 0.006	0.62TrpPro: 0.62 ± 0.006	0.467TrpGln: 0.467 ± 0.006	1.087TrpArg: 1.087 ± 0.009	1.009TrpSer: 1.009 ± 0.009	0.637TrpThr: 0.637 ± 0.006	0.791TrpVal: 0.791 ± 0.007	0.258TrpTrp: 0.258 ± 0.005	0.332TrpTyr: 0.332 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.946TyrAla: 1.946 ± 0.014	0.592TyrCys: 0.592 ± 0.006	1.408TyrAsp: 1.408 ± 0.009	1.352TyrGlu: 1.352 ± 0.009	1.085TyrPhe: 1.085 ± 0.007	2.02TyrGly: 2.02 ± 0.015	0.698TyrHis: 0.698 ± 0.007	1.22TyrIle: 1.22 ± 0.009	1.192TyrLys: 1.192 ± 0.009	2.537TyrLeu: 2.537 ± 0.014	0.695TyrMet: 0.695 ± 0.007	1.051TyrAsn: 1.051 ± 0.01	1.226TyrPro: 1.226 ± 0.01	0.861TyrGln: 0.861 ± 0.007	1.5TyrArg: 1.5 ± 0.011	1.948TyrSer: 1.948 ± 0.013	1.186TyrThr: 1.186 ± 0.009	1.592TyrVal: 1.592 ± 0.011	0.379TyrTrp: 0.379 ± 0.006	0.886TyrTyr: 0.886 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 38607 proteins (15483065 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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