Amino acid dipepetide frequency for Fur seal faeces associated circular DNA virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.984AlaAla: 3.984 ± 2.592
1.328AlaCys: 1.328 ± 0.864
3.984AlaAsp: 3.984 ± 0.772
2.656AlaGlu: 2.656 ± 1.728
0.0AlaPhe: 0.0 ± 0.0
5.312AlaGly: 5.312 ± 0.184
1.328AlaHis: 1.328 ± 0.864
1.328AlaIle: 1.328 ± 0.956
2.656AlaLys: 2.656 ± 0.092
6.64AlaLeu: 6.64 ± 2.5
0.0AlaMet: 0.0 ± 0.645
1.328AlaAsn: 1.328 ± 0.864
1.328AlaPro: 1.328 ± 0.956
1.328AlaGln: 1.328 ± 0.864
2.656AlaArg: 2.656 ± 0.092
5.312AlaSer: 5.312 ± 1.636
2.656AlaThr: 2.656 ± 0.092
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
1.328AlaTyr: 1.328 ± 0.864
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
3.984CysAsp: 3.984 ± 0.772
2.656CysGlu: 2.656 ± 0.092
3.984CysPhe: 3.984 ± 0.772
0.0CysGly: 0.0 ± 0.0
1.328CysHis: 1.328 ± 0.956
2.656CysIle: 2.656 ± 1.728
2.656CysLys: 2.656 ± 1.728
2.656CysLeu: 2.656 ± 0.092
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.328CysGln: 1.328 ± 0.956
1.328CysArg: 1.328 ± 0.864
2.656CysSer: 2.656 ± 1.728
1.328CysThr: 1.328 ± 0.864
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.328CysTyr: 1.328 ± 0.956
0.0CysXaa: 0.0 ± 0.0
Asp
1.328AspAla: 1.328 ± 0.864
1.328AspCys: 1.328 ± 0.864
2.656AspAsp: 2.656 ± 0.092
5.312AspGlu: 5.312 ± 3.823
0.0AspPhe: 0.0 ± 0.0
10.624AspGly: 10.624 ± 0.367
1.328AspHis: 1.328 ± 0.956
5.312AspIle: 5.312 ± 3.456
0.0AspLys: 0.0 ± 0.0
6.64AspLeu: 6.64 ± 1.139
2.656AspMet: 2.656 ± 1.912
0.0AspAsn: 0.0 ± 0.0
3.984AspPro: 3.984 ± 1.048
1.328AspGln: 1.328 ± 0.956
5.312AspArg: 5.312 ± 0.184
2.656AspSer: 2.656 ± 0.092
2.656AspThr: 2.656 ± 0.092
1.328AspVal: 1.328 ± 0.956
0.0AspTrp: 0.0 ± 0.0
2.656AspTyr: 2.656 ± 1.912
0.0AspXaa: 0.0 ± 0.0
Glu
3.984GluAla: 3.984 ± 2.592
0.0GluCys: 0.0 ± 0.0
2.656GluAsp: 2.656 ± 1.912
3.984GluGlu: 3.984 ± 1.048
3.984GluPhe: 3.984 ± 2.867
2.656GluGly: 2.656 ± 0.092
0.0GluHis: 0.0 ± 0.0
3.984GluIle: 3.984 ± 2.867
9.296GluLys: 9.296 ± 6.691
3.984GluLeu: 3.984 ± 1.048
1.328GluMet: 1.328 ± 0.864
2.656GluAsn: 2.656 ± 1.728
1.328GluPro: 1.328 ± 0.864
2.656GluGln: 2.656 ± 1.912
3.984GluArg: 3.984 ± 0.772
5.312GluSer: 5.312 ± 0.184
3.984GluThr: 3.984 ± 1.048
2.656GluVal: 2.656 ± 1.728
0.0GluTrp: 0.0 ± 0.0
3.984GluTyr: 3.984 ± 0.772
0.0GluXaa: 0.0 ± 0.0
Phe
2.656PheAla: 2.656 ± 0.092
1.328PheCys: 1.328 ± 0.956
6.64PheAsp: 6.64 ± 2.959
1.328PheGlu: 1.328 ± 0.864
1.328PhePhe: 1.328 ± 0.864
2.656PheGly: 2.656 ± 0.092
0.0PheHis: 0.0 ± 0.0
1.328PheIle: 1.328 ± 0.864
2.656PheLys: 2.656 ± 1.728
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
6.64PheAsn: 6.64 ± 4.779
3.984PhePro: 3.984 ± 1.048
1.328PheGln: 1.328 ± 0.956
0.0PheArg: 0.0 ± 0.0
0.0PheSer: 0.0 ± 0.0
1.328PheThr: 1.328 ± 0.864
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
2.656PheTyr: 2.656 ± 1.728
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
2.656GlyAsp: 2.656 ± 1.728
2.656GlyGlu: 2.656 ± 1.912
1.328GlyPhe: 1.328 ± 0.864
2.656GlyGly: 2.656 ± 0.092
1.328GlyHis: 1.328 ± 0.956
5.312GlyIle: 5.312 ± 1.636
7.968GlyLys: 7.968 ± 2.095
3.984GlyLeu: 3.984 ± 1.048
2.656GlyMet: 2.656 ± 1.728
2.656GlyAsn: 2.656 ± 0.092
5.312GlyPro: 5.312 ± 0.184
3.984GlyGln: 3.984 ± 0.772
3.984GlyArg: 3.984 ± 0.772
7.968GlySer: 7.968 ± 2.095
2.656GlyThr: 2.656 ± 0.092
1.328GlyVal: 1.328 ± 0.864
2.656GlyTrp: 2.656 ± 1.728
6.64GlyTyr: 6.64 ± 1.139
0.0GlyXaa: 0.0 ± 0.0
His
1.328HisAla: 1.328 ± 0.864
3.984HisCys: 3.984 ± 2.867
2.656HisAsp: 2.656 ± 1.912
1.328HisGlu: 1.328 ± 0.864
1.328HisPhe: 1.328 ± 0.956
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.656HisLeu: 2.656 ± 0.092
0.0HisMet: 0.0 ± 0.0
2.656HisAsn: 2.656 ± 1.728
1.328HisPro: 1.328 ± 0.956
0.0HisGln: 0.0 ± 0.0
1.328HisArg: 1.328 ± 0.956
0.0HisSer: 0.0 ± 0.0
1.328HisThr: 1.328 ± 0.956
1.328HisVal: 1.328 ± 0.956
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.312IleAla: 5.312 ± 3.456
1.328IleCys: 1.328 ± 0.864
3.984IleAsp: 3.984 ± 2.592
5.312IleGlu: 5.312 ± 0.184
2.656IlePhe: 2.656 ± 1.728
3.984IleGly: 3.984 ± 1.048
1.328IleHis: 1.328 ± 0.956
1.328IleIle: 1.328 ± 0.864
5.312IleLys: 5.312 ± 0.184
3.984IleLeu: 3.984 ± 2.867
0.0IleMet: 0.0 ± 0.0
1.328IleAsn: 1.328 ± 0.864
3.984IlePro: 3.984 ± 1.048
1.328IleGln: 1.328 ± 0.956
3.984IleArg: 3.984 ± 0.772
6.64IleSer: 6.64 ± 1.139
1.328IleThr: 1.328 ± 0.864
5.312IleVal: 5.312 ± 2.003
1.328IleTrp: 1.328 ± 0.956
1.328IleTyr: 1.328 ± 0.956
0.0IleXaa: 0.0 ± 0.0
Lys
1.328LysAla: 1.328 ± 0.864
3.984LysCys: 3.984 ± 1.048
2.656LysAsp: 2.656 ± 1.912
7.968LysGlu: 7.968 ± 2.095
1.328LysPhe: 1.328 ± 0.956
2.656LysGly: 2.656 ± 0.092
1.328LysHis: 1.328 ± 0.956
2.656LysIle: 2.656 ± 0.092
2.656LysLys: 2.656 ± 0.092
1.328LysLeu: 1.328 ± 0.956
2.656LysMet: 2.656 ± 0.092
1.328LysAsn: 1.328 ± 0.956
0.0LysPro: 0.0 ± 0.0
1.328LysGln: 1.328 ± 0.864
10.624LysArg: 10.624 ± 2.187
5.312LysSer: 5.312 ± 1.636
2.656LysThr: 2.656 ± 1.912
5.312LysVal: 5.312 ± 1.636
0.0LysTrp: 0.0 ± 0.0
2.656LysTyr: 2.656 ± 1.912
0.0LysXaa: 0.0 ± 0.0
Leu
5.312LeuAla: 5.312 ± 0.184
1.328LeuCys: 1.328 ± 0.864
2.656LeuAsp: 2.656 ± 1.912
7.968LeuGlu: 7.968 ± 3.915
5.312LeuPhe: 5.312 ± 2.003
1.328LeuGly: 1.328 ± 0.956
1.328LeuHis: 1.328 ± 0.956
5.312LeuIle: 5.312 ± 0.184
5.312LeuLys: 5.312 ± 2.003
3.984LeuLeu: 3.984 ± 1.048
5.312LeuMet: 5.312 ± 0.552
2.656LeuAsn: 2.656 ± 0.092
6.64LeuPro: 6.64 ± 4.32
1.328LeuGln: 1.328 ± 0.864
2.656LeuArg: 2.656 ± 1.728
2.656LeuSer: 2.656 ± 0.092
6.64LeuThr: 6.64 ± 1.139
5.312LeuVal: 5.312 ± 1.636
0.0LeuTrp: 0.0 ± 0.0
3.984LeuTyr: 3.984 ± 0.772
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.328MetGly: 1.328 ± 0.864
1.328MetHis: 1.328 ± 0.956
2.656MetIle: 2.656 ± 1.912
0.0MetLys: 0.0 ± 0.0
1.328MetLeu: 1.328 ± 0.864
0.0MetMet: 0.0 ± 0.0
1.328MetAsn: 1.328 ± 0.864
3.984MetPro: 3.984 ± 1.048
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
3.984MetSer: 3.984 ± 2.592
1.328MetThr: 1.328 ± 0.956
2.656MetVal: 2.656 ± 1.728
2.656MetTrp: 2.656 ± 0.092
1.328MetTyr: 1.328 ± 0.956
0.0MetXaa: 0.0 ± 0.0
Asn
1.328AsnAla: 1.328 ± 0.864
0.0AsnCys: 0.0 ± 0.0
1.328AsnAsp: 1.328 ± 0.956
0.0AsnGlu: 0.0 ± 0.0
1.328AsnPhe: 1.328 ± 0.864
3.984AsnGly: 3.984 ± 0.772
1.328AsnHis: 1.328 ± 0.864
3.984AsnIle: 3.984 ± 0.772
1.328AsnLys: 1.328 ± 0.864
5.312AsnLeu: 5.312 ± 0.184
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
6.64AsnPro: 6.64 ± 1.139
0.0AsnGln: 0.0 ± 0.0
5.312AsnArg: 5.312 ± 2.003
2.656AsnSer: 2.656 ± 0.092
1.328AsnThr: 1.328 ± 0.864
0.0AsnVal: 0.0 ± 0.0
2.656AsnTrp: 2.656 ± 0.092
2.656AsnTyr: 2.656 ± 0.092
0.0AsnXaa: 0.0 ± 0.0
Pro
6.64ProAla: 6.64 ± 0.68
1.328ProCys: 1.328 ± 0.864
3.984ProAsp: 3.984 ± 2.867
5.312ProGlu: 5.312 ± 1.636
1.328ProPhe: 1.328 ± 0.956
2.656ProGly: 2.656 ± 0.092
0.0ProHis: 0.0 ± 0.0
5.312ProIle: 5.312 ± 0.184
2.656ProLys: 2.656 ± 0.092
3.984ProLeu: 3.984 ± 0.772
0.0ProMet: 0.0 ± 0.0
3.984ProAsn: 3.984 ± 0.772
1.328ProPro: 1.328 ± 0.956
2.656ProGln: 2.656 ± 1.912
2.656ProArg: 2.656 ± 0.092
2.656ProSer: 2.656 ± 0.092
1.328ProThr: 1.328 ± 0.864
2.656ProVal: 2.656 ± 1.728
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.328GlnAla: 1.328 ± 0.864
1.328GlnCys: 1.328 ± 0.956
2.656GlnAsp: 2.656 ± 0.092
1.328GlnGlu: 1.328 ± 0.956
0.0GlnPhe: 0.0 ± 0.0
1.328GlnGly: 1.328 ± 0.956
1.328GlnHis: 1.328 ± 0.956
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
5.312GlnLeu: 5.312 ± 0.184
1.328GlnMet: 1.328 ± 0.956
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
1.328GlnArg: 1.328 ± 0.864
0.0GlnSer: 0.0 ± 0.0
1.328GlnThr: 1.328 ± 0.864
3.984GlnVal: 3.984 ± 2.867
2.656GlnTrp: 2.656 ± 1.728
5.312GlnTyr: 5.312 ± 0.184
0.0GlnXaa: 0.0 ± 0.0
Arg
3.984ArgAla: 3.984 ± 0.772
2.656ArgCys: 2.656 ± 1.728
1.328ArgAsp: 1.328 ± 0.956
3.984ArgGlu: 3.984 ± 1.048
6.64ArgPhe: 6.64 ± 1.139
3.984ArgGly: 3.984 ± 0.772
2.656ArgHis: 2.656 ± 0.092
2.656ArgIle: 2.656 ± 0.092
3.984ArgLys: 3.984 ± 2.592
3.984ArgLeu: 3.984 ± 1.048
2.656ArgMet: 2.656 ± 1.728
3.984ArgAsn: 3.984 ± 0.772
1.328ArgPro: 1.328 ± 0.864
3.984ArgGln: 3.984 ± 1.048
15.936ArgArg: 15.936 ± 3.089
7.968ArgSer: 7.968 ± 0.276
2.656ArgThr: 2.656 ± 1.728
2.656ArgVal: 2.656 ± 0.092
0.0ArgTrp: 0.0 ± 0.0
9.296ArgTyr: 9.296 ± 2.408
0.0ArgXaa: 0.0 ± 0.0
Ser
1.328SerAla: 1.328 ± 0.864
5.312SerCys: 5.312 ± 3.456
7.968SerAsp: 7.968 ± 0.276
2.656SerGlu: 2.656 ± 0.092
1.328SerPhe: 1.328 ± 0.864
11.952SerGly: 11.952 ± 0.497
2.656SerHis: 2.656 ± 0.092
3.984SerIle: 3.984 ± 1.048
2.656SerLys: 2.656 ± 0.092
5.312SerLeu: 5.312 ± 3.456
1.328SerMet: 1.328 ± 0.956
1.328SerAsn: 1.328 ± 0.956
3.984SerPro: 3.984 ± 2.592
1.328SerGln: 1.328 ± 0.864
5.312SerArg: 5.312 ± 3.456
3.984SerSer: 3.984 ± 1.048
2.656SerThr: 2.656 ± 1.912
3.984SerVal: 3.984 ± 0.772
2.656SerTrp: 2.656 ± 0.092
3.984SerTyr: 3.984 ± 0.772
0.0SerXaa: 0.0 ± 0.0
Thr
1.328ThrAla: 1.328 ± 0.956
0.0ThrCys: 0.0 ± 0.0
2.656ThrAsp: 2.656 ± 1.728
2.656ThrGlu: 2.656 ± 1.728
1.328ThrPhe: 1.328 ± 0.864
3.984ThrGly: 3.984 ± 1.048
1.328ThrHis: 1.328 ± 0.864
5.312ThrIle: 5.312 ± 0.184
3.984ThrLys: 3.984 ± 2.867
2.656ThrLeu: 2.656 ± 1.728
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
0.0ThrPro: 0.0 ± 0.0
0.0ThrGln: 0.0 ± 0.0
1.328ThrArg: 1.328 ± 0.956
3.984ThrSer: 3.984 ± 2.592
3.984ThrThr: 3.984 ± 0.772
5.312ThrVal: 5.312 ± 0.184
2.656ThrTrp: 2.656 ± 1.912
3.984ThrTyr: 3.984 ± 0.772
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
2.656ValCys: 2.656 ± 1.728
1.328ValAsp: 1.328 ± 0.864
0.0ValGlu: 0.0 ± 0.0
0.0ValPhe: 0.0 ± 0.0
2.656ValGly: 2.656 ± 0.092
0.0ValHis: 0.0 ± 0.0
2.656ValIle: 2.656 ± 1.912
3.984ValLys: 3.984 ± 2.867
5.312ValLeu: 5.312 ± 2.003
0.0ValMet: 0.0 ± 0.0
2.656ValAsn: 2.656 ± 0.092
2.656ValPro: 2.656 ± 1.728
0.0ValGln: 0.0 ± 0.0
9.296ValArg: 9.296 ± 2.408
5.312ValSer: 5.312 ± 3.456
2.656ValThr: 2.656 ± 1.728
1.328ValVal: 1.328 ± 0.864
0.0ValTrp: 0.0 ± 0.0
6.64ValTyr: 6.64 ± 1.139
0.0ValXaa: 0.0 ± 0.0
Trp
2.656TrpAla: 2.656 ± 1.912
0.0TrpCys: 0.0 ± 0.0
1.328TrpAsp: 1.328 ± 0.956
1.328TrpGlu: 1.328 ± 0.864
1.328TrpPhe: 1.328 ± 0.956
0.0TrpGly: 0.0 ± 0.0
1.328TrpHis: 1.328 ± 0.956
2.656TrpIle: 2.656 ± 0.092
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.328TrpMet: 1.328 ± 0.864
1.328TrpAsn: 1.328 ± 0.864
0.0TrpPro: 0.0 ± 0.0
1.328TrpGln: 1.328 ± 0.864
1.328TrpArg: 1.328 ± 0.864
1.328TrpSer: 1.328 ± 0.864
1.328TrpThr: 1.328 ± 0.864
0.0TrpVal: 0.0 ± 0.0
1.328TrpTrp: 1.328 ± 0.956
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.656TyrAla: 2.656 ± 0.092
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
3.984TyrGlu: 3.984 ± 2.867
1.328TyrPhe: 1.328 ± 0.956
3.984TyrGly: 3.984 ± 2.592
0.0TyrHis: 0.0 ± 0.0
2.656TyrIle: 2.656 ± 0.092
2.656TyrLys: 2.656 ± 0.092
7.968TyrLeu: 7.968 ± 2.095
1.328TyrMet: 1.328 ± 0.956
5.312TyrAsn: 5.312 ± 0.184
2.656TyrPro: 2.656 ± 1.912
5.312TyrGln: 5.312 ± 0.184
7.968TyrArg: 7.968 ± 1.544
5.312TyrSer: 5.312 ± 1.636
1.328TyrThr: 1.328 ± 0.864
3.984TyrVal: 3.984 ± 0.772
1.328TyrTrp: 1.328 ± 0.864
1.328TyrTyr: 1.328 ± 0.956
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (754 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski