Amino acid dipepetide frequency for Odobenus rosmarus divergens (Pacific walrus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.234AlaAla: 7.234 ± 0.044	1.406AlaCys: 1.406 ± 0.011	2.996AlaAsp: 2.996 ± 0.016	4.855AlaGlu: 4.855 ± 0.027	2.698AlaPhe: 2.698 ± 0.018	4.962AlaGly: 4.962 ± 0.026	1.566AlaHis: 1.566 ± 0.013	2.761AlaIle: 2.761 ± 0.013	3.4AlaLys: 3.4 ± 0.019	7.252AlaLeu: 7.252 ± 0.032	1.499AlaMet: 1.499 ± 0.01	2.045AlaAsn: 2.045 ± 0.013	4.446AlaPro: 4.446 ± 0.028	3.275AlaGln: 3.275 ± 0.019	3.861AlaArg: 3.861 ± 0.021	5.797AlaSer: 5.797 ± 0.026	3.563AlaThr: 3.563 ± 0.021	4.759AlaVal: 4.759 ± 0.017	0.79AlaTrp: 0.79 ± 0.008	1.564AlaTyr: 1.564 ± 0.011	0.006AlaXaa: 0.006 ± 0.001
Cys	1.27CysAla: 1.27 ± 0.011	0.619CysCys: 0.619 ± 0.012	1.013CysAsp: 1.013 ± 0.01	1.244CysGlu: 1.244 ± 0.012	0.821CysPhe: 0.821 ± 0.007	1.784CysGly: 1.784 ± 0.024	0.656CysHis: 0.656 ± 0.007	0.936CysIle: 0.936 ± 0.01	1.128CysLys: 1.128 ± 0.013	2.091CysLeu: 2.091 ± 0.013	0.4CysMet: 0.4 ± 0.005	0.801CysAsn: 0.801 ± 0.009	1.362CysPro: 1.362 ± 0.013	1.028CysGln: 1.028 ± 0.011	1.303CysArg: 1.303 ± 0.012	1.945CysSer: 1.945 ± 0.014	1.068CysThr: 1.068 ± 0.01	1.291CysVal: 1.291 ± 0.012	0.28CysTrp: 0.28 ± 0.004	0.582CysTyr: 0.582 ± 0.007	0.002CysXaa: 0.002 ± 0.0
Asp	2.893AspAla: 2.893 ± 0.015	1.047AspCys: 1.047 ± 0.012	2.671AspAsp: 2.671 ± 0.018	3.455AspGlu: 3.455 ± 0.018	2.137AspPhe: 2.137 ± 0.013	3.344AspGly: 3.344 ± 0.02	1.144AspHis: 1.144 ± 0.009	2.566AspIle: 2.566 ± 0.015	2.515AspLys: 2.515 ± 0.015	5.017AspLeu: 5.017 ± 0.02	1.123AspMet: 1.123 ± 0.009	1.689AspAsn: 1.689 ± 0.014	2.981AspPro: 2.981 ± 0.017	1.819AspGln: 1.819 ± 0.013	2.481AspArg: 2.481 ± 0.015	4.182AspSer: 4.182 ± 0.02	2.414AspThr: 2.414 ± 0.013	3.049AspVal: 3.049 ± 0.018	0.624AspTrp: 0.624 ± 0.007	1.486AspTyr: 1.486 ± 0.011	0.004AspXaa: 0.004 ± 0.0
Glu	5.328GluAla: 5.328 ± 0.026	1.446GluCys: 1.446 ± 0.022	4.426GluAsp: 4.426 ± 0.021	8.022GluGlu: 8.022 ± 0.051	2.029GluPhe: 2.029 ± 0.011	4.28GluGly: 4.28 ± 0.022	1.495GluHis: 1.495 ± 0.01	3.092GluIle: 3.092 ± 0.02	5.311GluLys: 5.311 ± 0.034	6.403GluLeu: 6.403 ± 0.029	1.678GluMet: 1.678 ± 0.011	3.065GluAsn: 3.065 ± 0.019	3.313GluPro: 3.313 ± 0.022	3.133GluGln: 3.133 ± 0.024	4.098GluArg: 4.098 ± 0.024	4.33GluSer: 4.33 ± 0.02	3.28GluThr: 3.28 ± 0.018	4.143GluVal: 4.143 ± 0.021	0.686GluTrp: 0.686 ± 0.007	1.602GluTyr: 1.602 ± 0.014	0.005GluXaa: 0.005 ± 0.001
Phe	2.011PheAla: 2.011 ± 0.013	0.929PheCys: 0.929 ± 0.008	1.692PheAsp: 1.692 ± 0.012	2.014PheGlu: 2.014 ± 0.012	1.657PhePhe: 1.657 ± 0.017	2.262PheGly: 2.262 ± 0.016	1.022PheHis: 1.022 ± 0.008	1.854PheIle: 1.854 ± 0.013	1.77PheLys: 1.77 ± 0.012	4.048PheLeu: 4.048 ± 0.02	0.792PheMet: 0.792 ± 0.007	1.329PheAsn: 1.329 ± 0.011	2.002PhePro: 2.002 ± 0.012	1.777PheGln: 1.777 ± 0.01	1.985PheArg: 1.985 ± 0.013	3.402PheSer: 3.402 ± 0.017	2.018PheThr: 2.018 ± 0.013	2.169PheVal: 2.169 ± 0.013	0.487PheTrp: 0.487 ± 0.006	1.175PheTyr: 1.175 ± 0.009	0.006PheXaa: 0.006 ± 0.001
Gly	4.784GlyAla: 4.784 ± 0.025	1.275GlyCys: 1.275 ± 0.011	3.193GlyAsp: 3.193 ± 0.019	4.245GlyGlu: 4.245 ± 0.025	2.422GlyPhe: 2.422 ± 0.016	5.51GlyGly: 5.51 ± 0.045	1.686GlyHis: 1.686 ± 0.013	2.721GlyIle: 2.721 ± 0.015	3.812GlyLys: 3.812 ± 0.023	5.956GlyLeu: 5.956 ± 0.026	1.332GlyMet: 1.332 ± 0.012	2.369GlyAsn: 2.369 ± 0.014	4.528GlyPro: 4.528 ± 0.048	2.799GlyGln: 2.799 ± 0.018	3.945GlyArg: 3.945 ± 0.022	5.912GlySer: 5.912 ± 0.032	3.614GlyThr: 3.614 ± 0.019	3.592GlyVal: 3.592 ± 0.018	0.798GlyTrp: 0.798 ± 0.008	1.733GlyTyr: 1.733 ± 0.014	0.008GlyXaa: 0.008 ± 0.001
His	1.341HisAla: 1.341 ± 0.011	0.7HisCys: 0.7 ± 0.008	0.88HisAsp: 0.88 ± 0.007	1.305HisGlu: 1.305 ± 0.01	1.073HisPhe: 1.073 ± 0.01	1.577HisGly: 1.577 ± 0.012	0.915HisHis: 0.915 ± 0.011	1.241HisIle: 1.241 ± 0.01	1.234HisLys: 1.234 ± 0.009	2.89HisLeu: 2.89 ± 0.017	0.588HisMet: 0.588 ± 0.007	0.861HisAsn: 0.861 ± 0.009	1.673HisPro: 1.673 ± 0.012	1.359HisGln: 1.359 ± 0.016	1.599HisArg: 1.599 ± 0.011	2.268HisSer: 2.268 ± 0.014	1.519HisThr: 1.519 ± 0.015	1.486HisVal: 1.486 ± 0.01	0.348HisTrp: 0.348 ± 0.004	0.823HisTyr: 0.823 ± 0.007	0.003HisXaa: 0.003 ± 0.0
Ile	2.56IleAla: 2.56 ± 0.014	1.064IleCys: 1.064 ± 0.009	2.016IleAsp: 2.016 ± 0.013	2.541IleGlu: 2.541 ± 0.016	1.897IlePhe: 1.897 ± 0.015	2.195IleGly: 2.195 ± 0.013	1.349IleHis: 1.349 ± 0.012	2.388IleIle: 2.388 ± 0.017	2.592IleLys: 2.592 ± 0.018	4.505IleLeu: 4.505 ± 0.023	1.034IleMet: 1.034 ± 0.009	1.787IleAsn: 1.787 ± 0.013	2.589IlePro: 2.589 ± 0.014	2.264IleGln: 2.264 ± 0.013	2.367IleArg: 2.367 ± 0.011	3.637IleSer: 3.637 ± 0.017	2.528IleThr: 2.528 ± 0.021	2.479IleVal: 2.479 ± 0.019	0.507IleTrp: 0.507 ± 0.006	1.386IleTyr: 1.386 ± 0.011	0.004IleXaa: 0.004 ± 0.001
Lys	3.989LysAla: 3.989 ± 0.023	1.123LysCys: 1.123 ± 0.01	3.102LysAsp: 3.102 ± 0.018	5.007LysGlu: 5.007 ± 0.032	1.726LysPhe: 1.726 ± 0.013	3.205LysGly: 3.205 ± 0.023	1.394LysHis: 1.394 ± 0.009	2.75LysIle: 2.75 ± 0.019	4.631LysLys: 4.631 ± 0.034	5.106LysLeu: 5.106 ± 0.024	1.46LysMet: 1.46 ± 0.013	2.366LysAsn: 2.366 ± 0.015	3.127LysPro: 3.127 ± 0.02	2.567LysGln: 2.567 ± 0.018	3.279LysArg: 3.279 ± 0.019	3.842LysSer: 3.842 ± 0.02	3.048LysThr: 3.048 ± 0.018	3.368LysVal: 3.368 ± 0.02	0.582LysTrp: 0.582 ± 0.007	1.559LysTyr: 1.559 ± 0.012	0.005LysXaa: 0.005 ± 0.001
Leu	6.884LeuAla: 6.884 ± 0.026	2.124LeuCys: 2.124 ± 0.015	4.721LeuAsp: 4.721 ± 0.02	7.11LeuGlu: 7.11 ± 0.035	3.366LeuPhe: 3.366 ± 0.018	5.98LeuGly: 5.98 ± 0.027	2.682LeuHis: 2.682 ± 0.015	3.837LeuIle: 3.837 ± 0.022	5.722LeuLys: 5.722 ± 0.025	10.691LeuLeu: 10.691 ± 0.047	2.027LeuMet: 2.027 ± 0.012	3.481LeuAsn: 3.481 ± 0.019	6.014LeuPro: 6.014 ± 0.03	5.68LeuGln: 5.68 ± 0.028	6.037LeuArg: 6.037 ± 0.025	7.868LeuSer: 7.868 ± 0.027	5.002LeuThr: 5.002 ± 0.019	5.549LeuVal: 5.549 ± 0.022	1.118LeuTrp: 1.118 ± 0.009	2.529LeuTyr: 2.529 ± 0.016	0.011LeuXaa: 0.011 ± 0.001
Met	1.991MetAla: 1.991 ± 0.01	0.394MetCys: 0.394 ± 0.005	1.281MetAsp: 1.281 ± 0.009	1.863MetGlu: 1.863 ± 0.012	0.75MetPhe: 0.75 ± 0.007	1.316MetGly: 1.316 ± 0.01	0.465MetHis: 0.465 ± 0.005	0.836MetIle: 0.836 ± 0.007	1.432MetLys: 1.432 ± 0.01	1.984MetLeu: 1.984 ± 0.013	0.583MetMet: 0.583 ± 0.007	0.921MetAsn: 0.921 ± 0.009	1.103MetPro: 1.103 ± 0.013	0.927MetGln: 0.927 ± 0.008	1.068MetArg: 1.068 ± 0.008	1.576MetSer: 1.576 ± 0.012	1.113MetThr: 1.113 ± 0.009	1.398MetVal: 1.398 ± 0.01	0.24MetTrp: 0.24 ± 0.004	0.6MetTyr: 0.6 ± 0.006	0.002MetXaa: 0.002 ± 0.0
Asn	2.054AsnAla: 2.054 ± 0.012	0.822AsnCys: 0.822 ± 0.008	1.504AsnAsp: 1.504 ± 0.011	2.177AsnGlu: 2.177 ± 0.013	1.47AsnPhe: 1.47 ± 0.008	2.449AsnGly: 2.449 ± 0.017	0.956AsnHis: 0.956 ± 0.008	2.1AsnIle: 2.1 ± 0.016	2.167AsnLys: 2.167 ± 0.016	3.684AsnLeu: 3.684 ± 0.018	0.919AsnMet: 0.919 ± 0.008	1.514AsnAsn: 1.514 ± 0.012	2.2AsnPro: 2.2 ± 0.013	1.64AsnGln: 1.64 ± 0.012	1.838AsnArg: 1.838 ± 0.01	3.083AsnSer: 3.083 ± 0.018	1.921AsnThr: 1.921 ± 0.012	2.177AsnVal: 2.177 ± 0.013	0.443AsnTrp: 0.443 ± 0.005	1.104AsnTyr: 1.104 ± 0.01	0.003AsnXaa: 0.003 ± 0.001
Pro	5.152ProAla: 5.152 ± 0.032	1.118ProCys: 1.118 ± 0.012	2.828ProAsp: 2.828 ± 0.017	4.499ProGlu: 4.499 ± 0.023	1.957ProPhe: 1.957 ± 0.012	5.503ProGly: 5.503 ± 0.056	1.491ProHis: 1.491 ± 0.012	1.859ProIle: 1.859 ± 0.014	2.806ProLys: 2.806 ± 0.025	5.322ProLeu: 5.322 ± 0.021	1.096ProMet: 1.096 ± 0.01	1.824ProAsn: 1.824 ± 0.013	6.531ProPro: 6.531 ± 0.055	2.907ProGln: 2.907 ± 0.022	3.528ProArg: 3.528 ± 0.023	5.722ProSer: 5.722 ± 0.029	3.126ProThr: 3.126 ± 0.021	3.821ProVal: 3.821 ± 0.02	0.689ProTrp: 0.689 ± 0.007	1.586ProTyr: 1.586 ± 0.018	0.01ProXaa: 0.01 ± 0.001
Gln	3.525GlnAla: 3.525 ± 0.019	0.916GlnCys: 0.916 ± 0.01	2.315GlnAsp: 2.315 ± 0.013	3.801GlnGlu: 3.801 ± 0.024	1.345GlnPhe: 1.345 ± 0.01	2.857GlnGly: 2.857 ± 0.018	1.29GlnHis: 1.29 ± 0.011	1.967GlnIle: 1.967 ± 0.011	2.901GlnLys: 2.901 ± 0.018	4.696GlnLeu: 4.696 ± 0.025	1.132GlnMet: 1.132 ± 0.01	1.817GlnAsn: 1.817 ± 0.013	2.876GlnPro: 2.876 ± 0.022	3.038GlnGln: 3.038 ± 0.037	2.999GlnArg: 2.999 ± 0.019	3.073GlnSer: 3.073 ± 0.018	2.301GlnThr: 2.301 ± 0.013	2.798GlnVal: 2.798 ± 0.014	0.526GlnTrp: 0.526 ± 0.006	1.162GlnTyr: 1.162 ± 0.008	0.005GlnXaa: 0.005 ± 0.001
Arg	4.061ArgAla: 4.061 ± 0.02	1.22ArgCys: 1.22 ± 0.012	2.798ArgAsp: 2.798 ± 0.014	4.078ArgGlu: 4.078 ± 0.025	1.848ArgPhe: 1.848 ± 0.013	3.81ArgGly: 3.81 ± 0.026	1.553ArgHis: 1.553 ± 0.011	2.449ArgIle: 2.449 ± 0.016	3.665ArgLys: 3.665 ± 0.019	5.472ArgLeu: 5.472 ± 0.024	1.19ArgMet: 1.19 ± 0.008	2.107ArgAsn: 2.107 ± 0.013	3.412ArgPro: 3.412 ± 0.02	2.639ArgGln: 2.639 ± 0.018	4.568ArgArg: 4.568 ± 0.026	4.329ArgSer: 4.329 ± 0.025	2.841ArgThr: 2.841 ± 0.014	3.186ArgVal: 3.186 ± 0.015	0.689ArgTrp: 0.689 ± 0.008	1.458ArgTyr: 1.458 ± 0.01	0.007ArgXaa: 0.007 ± 0.001
Ser	5.365SerAla: 5.365 ± 0.024	1.808SerCys: 1.808 ± 0.016	3.874SerAsp: 3.874 ± 0.019	5.175SerGlu: 5.175 ± 0.023	3.012SerPhe: 3.012 ± 0.015	5.723SerGly: 5.723 ± 0.028	2.073SerHis: 2.073 ± 0.012	3.154SerIle: 3.154 ± 0.016	4.007SerLys: 4.007 ± 0.022	8.056SerLeu: 8.056 ± 0.027	1.612SerMet: 1.612 ± 0.011	2.648SerAsn: 2.648 ± 0.014	6.086SerPro: 6.086 ± 0.039	3.799SerGln: 3.799 ± 0.02	4.568SerArg: 4.568 ± 0.024	9.296SerSer: 9.296 ± 0.048	4.381SerThr: 4.381 ± 0.026	4.851SerVal: 4.851 ± 0.02	1.055SerTrp: 1.055 ± 0.01	2.076SerTyr: 2.076 ± 0.014	0.009SerXaa: 0.009 ± 0.001
Thr	3.758ThrAla: 3.758 ± 0.02	1.267ThrCys: 1.267 ± 0.013	2.441ThrAsp: 2.441 ± 0.013	3.454ThrGlu: 3.454 ± 0.018	2.101ThrPhe: 2.101 ± 0.012	3.572ThrGly: 3.572 ± 0.023	1.297ThrHis: 1.297 ± 0.011	2.363ThrIle: 2.363 ± 0.018	2.579ThrLys: 2.579 ± 0.019	5.23ThrLeu: 5.23 ± 0.02	1.116ThrMet: 1.116 ± 0.009	1.715ThrAsn: 1.715 ± 0.011	3.578ThrPro: 3.578 ± 0.024	2.233ThrGln: 2.233 ± 0.013	2.454ThrArg: 2.454 ± 0.012	4.504ThrSer: 4.504 ± 0.023	2.92ThrThr: 2.92 ± 0.029	3.821ThrVal: 3.821 ± 0.025	0.663ThrTrp: 0.663 ± 0.009	1.431ThrTyr: 1.431 ± 0.011	0.006ThrXaa: 0.006 ± 0.001
Val	4.3ValAla: 4.3 ± 0.018	1.424ValCys: 1.424 ± 0.012	2.935ValAsp: 2.935 ± 0.017	3.81ValGlu: 3.81 ± 0.02	2.404ValPhe: 2.404 ± 0.013	3.458ValGly: 3.458 ± 0.017	1.577ValHis: 1.577 ± 0.01	2.894ValIle: 2.894 ± 0.02	3.33ValLys: 3.33 ± 0.018	6.215ValLeu: 6.215 ± 0.021	1.341ValMet: 1.341 ± 0.011	2.248ValAsn: 2.248 ± 0.016	3.699ValPro: 3.699 ± 0.021	2.686ValGln: 2.686 ± 0.013	3.084ValArg: 3.084 ± 0.014	4.8ValSer: 4.8 ± 0.022	3.695ValThr: 3.695 ± 0.025	3.997ValVal: 3.997 ± 0.019	0.702ValTrp: 0.702 ± 0.007	1.614ValTyr: 1.614 ± 0.01	0.006ValXaa: 0.006 ± 0.001
Trp	0.799TrpAla: 0.799 ± 0.007	0.243TrpCys: 0.243 ± 0.004	0.653TrpAsp: 0.653 ± 0.007	0.788TrpGlu: 0.788 ± 0.008	0.445TrpPhe: 0.445 ± 0.006	0.73TrpGly: 0.73 ± 0.008	0.301TrpHis: 0.301 ± 0.004	0.533TrpIle: 0.533 ± 0.006	0.781TrpLys: 0.781 ± 0.008	1.174TrpLeu: 1.174 ± 0.01	0.31TrpMet: 0.31 ± 0.005	0.532TrpAsn: 0.532 ± 0.006	0.52TrpPro: 0.52 ± 0.006	0.513TrpGln: 0.513 ± 0.007	0.73TrpArg: 0.73 ± 0.007	0.845TrpSer: 0.845 ± 0.009	0.655TrpThr: 0.655 ± 0.007	0.692TrpVal: 0.692 ± 0.008	0.193TrpTrp: 0.193 ± 0.004	0.333TrpTyr: 0.333 ± 0.005	0.002TrpXaa: 0.002 ± 0.0
Tyr	1.428TyrAla: 1.428 ± 0.012	0.677TyrCys: 0.677 ± 0.007	1.3TyrAsp: 1.3 ± 0.011	1.715TyrGlu: 1.715 ± 0.014	1.234TyrPhe: 1.234 ± 0.01	1.711TyrGly: 1.711 ± 0.012	0.771TyrHis: 0.771 ± 0.007	1.38TyrIle: 1.38 ± 0.01	1.448TyrLys: 1.448 ± 0.012	2.629TyrLeu: 2.629 ± 0.014	0.611TyrMet: 0.611 ± 0.006	1.101TyrAsn: 1.101 ± 0.01	1.325TyrPro: 1.325 ± 0.012	1.256TyrGln: 1.256 ± 0.009	1.582TyrArg: 1.582 ± 0.011	2.21TyrSer: 2.21 ± 0.013	1.49TyrThr: 1.49 ± 0.012	1.587TyrVal: 1.587 ± 0.012	0.35TyrTrp: 0.35 ± 0.005	0.952TyrTyr: 0.952 ± 0.009	0.003TyrXaa: 0.003 ± 0.0
Xaa	0.008XaaAla: 0.008 ± 0.001	0.003XaaCys: 0.003 ± 0.0	0.005XaaAsp: 0.005 ± 0.001	0.006XaaGlu: 0.006 ± 0.001	0.005XaaPhe: 0.005 ± 0.001	0.01XaaGly: 0.01 ± 0.001	0.003XaaHis: 0.003 ± 0.0	0.005XaaIle: 0.005 ± 0.001	0.006XaaLys: 0.006 ± 0.001	0.012XaaLeu: 0.012 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.004XaaAsn: 0.004 ± 0.001	0.008XaaPro: 0.008 ± 0.001	0.005XaaGln: 0.005 ± 0.001	0.006XaaArg: 0.006 ± 0.001	0.007XaaSer: 0.007 ± 0.001	0.005XaaThr: 0.005 ± 0.001	0.007XaaVal: 0.007 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.003XaaTyr: 0.003 ± 0.0	0.01XaaXaa: 0.01 ± 0.002

Statistics based on 29573 proteins (17273837 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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