Amino acid dipepetide frequency for Cohnella faecalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.496AlaAla: 10.496 ± 0.136	0.779AlaCys: 0.779 ± 0.024	5.144AlaAsp: 5.144 ± 0.068	6.213AlaGlu: 6.213 ± 0.084	3.628AlaPhe: 3.628 ± 0.049	7.638AlaGly: 7.638 ± 0.1	1.359AlaHis: 1.359 ± 0.031	5.572AlaIle: 5.572 ± 0.058	4.4AlaLys: 4.4 ± 0.065	8.985AlaLeu: 8.985 ± 0.099	2.305AlaMet: 2.305 ± 0.042	3.018AlaAsn: 3.018 ± 0.055	3.123AlaPro: 3.123 ± 0.058	2.665AlaGln: 2.665 ± 0.05	4.412AlaArg: 4.412 ± 0.06	6.374AlaSer: 6.374 ± 0.086	4.114AlaThr: 4.114 ± 0.084	6.988AlaVal: 6.988 ± 0.081	1.066AlaTrp: 1.066 ± 0.03	2.816AlaTyr: 2.816 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.6CysAla: 0.6 ± 0.025	0.138CysCys: 0.138 ± 0.01	0.386CysAsp: 0.386 ± 0.02	0.454CysGlu: 0.454 ± 0.018	0.314CysPhe: 0.314 ± 0.014	0.774CysGly: 0.774 ± 0.028	0.145CysHis: 0.145 ± 0.011	0.389CysIle: 0.389 ± 0.017	0.296CysLys: 0.296 ± 0.014	0.701CysLeu: 0.701 ± 0.024	0.189CysMet: 0.189 ± 0.012	0.212CysAsn: 0.212 ± 0.013	0.383CysPro: 0.383 ± 0.021	0.19CysGln: 0.19 ± 0.012	0.564CysArg: 0.564 ± 0.023	0.59CysSer: 0.59 ± 0.022	0.383CysThr: 0.383 ± 0.015	0.467CysVal: 0.467 ± 0.017	0.114CysTrp: 0.114 ± 0.008	0.238CysTyr: 0.238 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.407AspAla: 4.407 ± 0.066	0.363AspCys: 0.363 ± 0.018	2.708AspAsp: 2.708 ± 0.048	3.933AspGlu: 3.933 ± 0.066	2.098AspPhe: 2.098 ± 0.034	4.743AspGly: 4.743 ± 0.074	0.967AspHis: 0.967 ± 0.026	3.402AspIle: 3.402 ± 0.051	2.705AspLys: 2.705 ± 0.05	4.599AspLeu: 4.599 ± 0.058	1.191AspMet: 1.191 ± 0.027	1.888AspAsn: 1.888 ± 0.039	2.409AspPro: 2.409 ± 0.042	1.602AspGln: 1.602 ± 0.038	3.352AspArg: 3.352 ± 0.052	3.342AspSer: 3.342 ± 0.046	2.527AspThr: 2.527 ± 0.056	3.655AspVal: 3.655 ± 0.051	0.879AspTrp: 0.879 ± 0.028	1.973AspTyr: 1.973 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.519GluAla: 6.519 ± 0.089	0.385GluCys: 0.385 ± 0.017	3.029GluAsp: 3.029 ± 0.051	5.111GluGlu: 5.111 ± 0.082	2.058GluPhe: 2.058 ± 0.037	4.383GluGly: 4.383 ± 0.068	1.328GluHis: 1.328 ± 0.035	3.834GluIle: 3.834 ± 0.059	3.665GluLys: 3.665 ± 0.05	7.131GluLeu: 7.131 ± 0.101	1.743GluMet: 1.743 ± 0.037	2.219GluAsn: 2.219 ± 0.032	2.502GluPro: 2.502 ± 0.048	3.033GluGln: 3.033 ± 0.05	4.906GluArg: 4.906 ± 0.077	3.814GluSer: 3.814 ± 0.057	3.399GluThr: 3.399 ± 0.056	3.965GluVal: 3.965 ± 0.059	1.057GluTrp: 1.057 ± 0.032	1.848GluTyr: 1.848 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.719PheAla: 3.719 ± 0.058	0.354PheCys: 0.354 ± 0.016	2.479PheAsp: 2.479 ± 0.042	2.505PheGlu: 2.505 ± 0.044	1.847PhePhe: 1.847 ± 0.048	3.531PheGly: 3.531 ± 0.052	0.869PheHis: 0.869 ± 0.026	2.369PheIle: 2.369 ± 0.044	1.745PheLys: 1.745 ± 0.033	3.681PheLeu: 3.681 ± 0.061	0.945PheMet: 0.945 ± 0.027	1.427PheAsn: 1.427 ± 0.034	1.659PhePro: 1.659 ± 0.031	1.277PheGln: 1.277 ± 0.03	2.457PheArg: 2.457 ± 0.052	2.789PheSer: 2.789 ± 0.049	2.092PheThr: 2.092 ± 0.046	3.191PheVal: 3.191 ± 0.048	0.459PheTrp: 0.459 ± 0.018	1.277PheTyr: 1.277 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	6.492GlyAla: 6.492 ± 0.105	0.749GlyCys: 0.749 ± 0.025	3.721GlyAsp: 3.721 ± 0.055	4.718GlyGlu: 4.718 ± 0.062	3.195GlyPhe: 3.195 ± 0.057	6.008GlyGly: 6.008 ± 0.096	1.475GlyHis: 1.475 ± 0.031	5.37GlyIle: 5.37 ± 0.062	4.513GlyLys: 4.513 ± 0.06	7.401GlyLeu: 7.401 ± 0.075	2.304GlyMet: 2.304 ± 0.042	2.935GlyAsn: 2.935 ± 0.065	1.961GlyPro: 1.961 ± 0.037	2.705GlyGln: 2.705 ± 0.049	4.213GlyArg: 4.213 ± 0.075	5.511GlySer: 5.511 ± 0.1	4.987GlyThr: 4.987 ± 0.09	5.34GlyVal: 5.34 ± 0.065	1.235GlyTrp: 1.235 ± 0.033	2.866GlyTyr: 2.866 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.588HisAla: 1.588 ± 0.041	0.185HisCys: 0.185 ± 0.011	0.95HisAsp: 0.95 ± 0.026	1.147HisGlu: 1.147 ± 0.033	0.851HisPhe: 0.851 ± 0.027	1.447HisGly: 1.447 ± 0.032	0.521HisHis: 0.521 ± 0.023	1.123HisIle: 1.123 ± 0.031	0.661HisLys: 0.661 ± 0.024	1.926HisLeu: 1.926 ± 0.037	0.444HisMet: 0.444 ± 0.017	0.552HisAsn: 0.552 ± 0.02	1.16HisPro: 1.16 ± 0.032	0.579HisGln: 0.579 ± 0.022	1.209HisArg: 1.209 ± 0.031	1.24HisSer: 1.24 ± 0.033	0.942HisThr: 0.942 ± 0.025	1.241HisVal: 1.241 ± 0.029	0.29HisTrp: 0.29 ± 0.013	0.747HisTyr: 0.747 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	6.208IleAla: 6.208 ± 0.077	0.529IleCys: 0.529 ± 0.02	3.636IleAsp: 3.636 ± 0.053	3.947IleGlu: 3.947 ± 0.054	2.056IlePhe: 2.056 ± 0.037	5.477IleGly: 5.477 ± 0.076	1.22IleHis: 1.22 ± 0.028	3.25IleIle: 3.25 ± 0.062	2.581IleLys: 2.581 ± 0.045	4.935IleLeu: 4.935 ± 0.068	1.296IleMet: 1.296 ± 0.029	1.927IleAsn: 1.927 ± 0.038	2.965IlePro: 2.965 ± 0.046	1.973IleGln: 1.973 ± 0.04	4.123IleArg: 4.123 ± 0.072	3.875IleSer: 3.875 ± 0.055	3.097IleThr: 3.097 ± 0.055	5.497IleVal: 5.497 ± 0.061	0.654IleTrp: 0.654 ± 0.022	1.735IleTyr: 1.735 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.494LysAla: 4.494 ± 0.057	0.226LysCys: 0.226 ± 0.014	2.74LysAsp: 2.74 ± 0.051	3.725LysGlu: 3.725 ± 0.053	1.538LysPhe: 1.538 ± 0.037	3.282LysGly: 3.282 ± 0.044	0.943LysHis: 0.943 ± 0.028	2.761LysIle: 2.761 ± 0.049	2.922LysLys: 2.922 ± 0.052	5.594LysLeu: 5.594 ± 0.091	1.313LysMet: 1.313 ± 0.028	1.768LysAsn: 1.768 ± 0.037	2.349LysPro: 2.349 ± 0.04	2.038LysGln: 2.038 ± 0.039	2.942LysArg: 2.942 ± 0.043	3.058LysSer: 3.058 ± 0.049	2.808LysThr: 2.808 ± 0.049	3.313LysVal: 3.313 ± 0.052	0.701LysTrp: 0.701 ± 0.021	1.548LysTyr: 1.548 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	9.228LeuAla: 9.228 ± 0.105	0.824LeuCys: 0.824 ± 0.024	5.04LeuAsp: 5.04 ± 0.059	6.081LeuGlu: 6.081 ± 0.083	4.602LeuPhe: 4.602 ± 0.072	6.708LeuGly: 6.708 ± 0.075	1.925LeuHis: 1.925 ± 0.042	5.717LeuIle: 5.717 ± 0.075	4.95LeuLys: 4.95 ± 0.05	11.061LeuLeu: 11.061 ± 0.144	2.237LeuMet: 2.237 ± 0.048	3.774LeuAsn: 3.774 ± 0.052	4.753LeuPro: 4.753 ± 0.069	3.598LeuGln: 3.598 ± 0.056	5.697LeuArg: 5.697 ± 0.075	7.381LeuSer: 7.381 ± 0.073	5.833LeuThr: 5.833 ± 0.071	6.284LeuVal: 6.284 ± 0.071	1.013LeuTrp: 1.013 ± 0.03	2.927LeuTyr: 2.927 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.086MetAla: 2.086 ± 0.044	0.147MetCys: 0.147 ± 0.011	1.284MetAsp: 1.284 ± 0.028	1.673MetGlu: 1.673 ± 0.037	0.939MetPhe: 0.939 ± 0.024	1.568MetGly: 1.568 ± 0.034	0.391MetHis: 0.391 ± 0.013	1.545MetIle: 1.545 ± 0.037	1.663MetLys: 1.663 ± 0.032	2.633MetLeu: 2.633 ± 0.049	0.67MetMet: 0.67 ± 0.026	1.258MetAsn: 1.258 ± 0.026	1.099MetPro: 1.099 ± 0.031	0.794MetGln: 0.794 ± 0.022	1.401MetArg: 1.401 ± 0.041	1.773MetSer: 1.773 ± 0.038	1.648MetThr: 1.648 ± 0.028	1.477MetVal: 1.477 ± 0.029	0.204MetTrp: 0.204 ± 0.012	0.616MetTyr: 0.616 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.025AsnAla: 3.025 ± 0.05	0.219AsnCys: 0.219 ± 0.013	1.961AsnAsp: 1.961 ± 0.037	2.43AsnGlu: 2.43 ± 0.046	1.128AsnPhe: 1.128 ± 0.028	3.672AsnGly: 3.672 ± 0.076	0.741AsnHis: 0.741 ± 0.023	1.98AsnIle: 1.98 ± 0.036	1.85AsnLys: 1.85 ± 0.04	2.962AsnLeu: 2.962 ± 0.046	0.829AsnMet: 0.829 ± 0.025	1.461AsnAsn: 1.461 ± 0.05	1.937AsnPro: 1.937 ± 0.037	1.143AsnGln: 1.143 ± 0.028	2.362AsnArg: 2.362 ± 0.037	2.167AsnSer: 2.167 ± 0.051	1.721AsnThr: 1.721 ± 0.049	2.759AsnVal: 2.759 ± 0.049	0.493AsnTrp: 0.493 ± 0.023	1.194AsnTyr: 1.194 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	3.862ProAla: 3.862 ± 0.069	0.25ProCys: 0.25 ± 0.012	2.758ProAsp: 2.758 ± 0.047	3.295ProGlu: 3.295 ± 0.054	2.05ProPhe: 2.05 ± 0.044	3.192ProGly: 3.192 ± 0.052	0.794ProHis: 0.794 ± 0.027	2.649ProIle: 2.649 ± 0.048	1.725ProLys: 1.725 ± 0.04	4.13ProLeu: 4.13 ± 0.064	0.896ProMet: 0.896 ± 0.023	1.524ProAsn: 1.524 ± 0.035	1.402ProPro: 1.402 ± 0.037	1.276ProGln: 1.276 ± 0.033	1.651ProArg: 1.651 ± 0.037	3.082ProSer: 3.082 ± 0.051	2.07ProThr: 2.07 ± 0.044	3.333ProVal: 3.333 ± 0.054	0.505ProTrp: 0.505 ± 0.02	1.56ProTyr: 1.56 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.35GlnAla: 3.35 ± 0.054	0.175GlnCys: 0.175 ± 0.011	1.392GlnAsp: 1.392 ± 0.026	2.029GlnGlu: 2.029 ± 0.041	1.295GlnPhe: 1.295 ± 0.028	2.387GlnGly: 2.387 ± 0.061	0.536GlnHis: 0.536 ± 0.02	2.135GlnIle: 2.135 ± 0.039	1.566GlnLys: 1.566 ± 0.035	3.818GlnLeu: 3.818 ± 0.061	0.896GlnMet: 0.896 ± 0.025	1.073GlnAsn: 1.073 ± 0.028	1.435GlnPro: 1.435 ± 0.028	1.517GlnGln: 1.517 ± 0.043	1.863GlnArg: 1.863 ± 0.041	2.334GlnSer: 2.334 ± 0.04	1.944GlnThr: 1.944 ± 0.037	2.162GlnVal: 2.162 ± 0.038	0.598GlnTrp: 0.598 ± 0.032	1.088GlnTyr: 1.088 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	4.139ArgAla: 4.139 ± 0.067	0.426ArgCys: 0.426 ± 0.02	2.704ArgAsp: 2.704 ± 0.044	4.165ArgGlu: 4.165 ± 0.066	2.625ArgPhe: 2.625 ± 0.042	3.491ArgGly: 3.491 ± 0.055	1.346ArgHis: 1.346 ± 0.035	4.026ArgIle: 4.026 ± 0.059	3.366ArgLys: 3.366 ± 0.05	6.54ArgLeu: 6.54 ± 0.085	1.857ArgMet: 1.857 ± 0.037	2.171ArgAsn: 2.171 ± 0.038	2.114ArgPro: 2.114 ± 0.047	2.205ArgGln: 2.205 ± 0.042	3.906ArgArg: 3.906 ± 0.078	3.98ArgSer: 3.98 ± 0.064	3.216ArgThr: 3.216 ± 0.049	3.394ArgVal: 3.394 ± 0.048	0.802ArgTrp: 0.802 ± 0.022	2.02ArgTyr: 2.02 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.184SerAla: 6.184 ± 0.072	0.487SerCys: 0.487 ± 0.017	3.532SerAsp: 3.532 ± 0.053	4.082SerGlu: 4.082 ± 0.059	3.243SerPhe: 3.243 ± 0.052	6.262SerGly: 6.262 ± 0.09	1.156SerHis: 1.156 ± 0.03	4.115SerIle: 4.115 ± 0.053	3.035SerLys: 3.035 ± 0.055	6.637SerLeu: 6.637 ± 0.068	1.686SerMet: 1.686 ± 0.034	2.375SerAsn: 2.375 ± 0.051	2.915SerPro: 2.915 ± 0.049	1.856SerGln: 1.856 ± 0.041	3.798SerArg: 3.798 ± 0.062	5.085SerSer: 5.085 ± 0.066	3.289SerThr: 3.289 ± 0.071	5.168SerVal: 5.168 ± 0.085	0.926SerTrp: 0.926 ± 0.024	2.303SerTyr: 2.303 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.185ThrAla: 5.185 ± 0.088	0.305ThrCys: 0.305 ± 0.015	3.001ThrAsp: 3.001 ± 0.053	3.22ThrGlu: 3.22 ± 0.06	2.368ThrPhe: 2.368 ± 0.054	4.769ThrGly: 4.769 ± 0.129	0.836ThrHis: 0.836 ± 0.022	3.759ThrIle: 3.759 ± 0.06	2.364ThrLys: 2.364 ± 0.045	5.335ThrLeu: 5.335 ± 0.064	1.217ThrMet: 1.217 ± 0.024	1.853ThrAsn: 1.853 ± 0.045	2.497ThrPro: 2.497 ± 0.051	1.343ThrGln: 1.343 ± 0.032	2.339ThrArg: 2.339 ± 0.044	3.406ThrSer: 3.406 ± 0.064	2.925ThrThr: 2.925 ± 0.062	4.964ThrVal: 4.964 ± 0.103	0.631ThrTrp: 0.631 ± 0.024	1.885ThrTyr: 1.885 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	5.941ValAla: 5.941 ± 0.07	0.632ValCys: 0.632 ± 0.025	3.64ValAsp: 3.64 ± 0.045	4.248ValGlu: 4.248 ± 0.058	2.848ValPhe: 2.848 ± 0.043	4.859ValGly: 4.859 ± 0.063	1.371ValHis: 1.371 ± 0.033	4.376ValIle: 4.376 ± 0.057	3.83ValLys: 3.83 ± 0.06	6.981ValLeu: 6.981 ± 0.075	1.708ValMet: 1.708 ± 0.032	2.669ValAsn: 2.669 ± 0.048	3.411ValPro: 3.411 ± 0.058	2.359ValGln: 2.359 ± 0.042	4.246ValArg: 4.246 ± 0.054	5.135ValSer: 5.135 ± 0.058	4.617ValThr: 4.617 ± 0.099	5.364ValVal: 5.364 ± 0.07	0.951ValTrp: 0.951 ± 0.03	2.374ValTyr: 2.374 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.927TrpAla: 0.927 ± 0.027	0.094TrpCys: 0.094 ± 0.008	0.715TrpAsp: 0.715 ± 0.029	0.769TrpGlu: 0.769 ± 0.024	0.555TrpPhe: 0.555 ± 0.021	0.824TrpGly: 0.824 ± 0.027	0.273TrpHis: 0.273 ± 0.012	0.893TrpIle: 0.893 ± 0.029	0.766TrpLys: 0.766 ± 0.023	1.517TrpLeu: 1.517 ± 0.041	0.385TrpMet: 0.385 ± 0.016	0.692TrpAsn: 0.692 ± 0.023	0.397TrpPro: 0.397 ± 0.017	0.478TrpGln: 0.478 ± 0.016	0.769TrpArg: 0.769 ± 0.025	0.94TrpSer: 0.94 ± 0.03	0.851TrpThr: 0.851 ± 0.03	0.737TrpVal: 0.737 ± 0.023	0.193TrpTrp: 0.193 ± 0.011	0.423TrpTyr: 0.423 ± 0.028	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.644TyrAla: 2.644 ± 0.04	0.257TyrCys: 0.257 ± 0.013	1.924TyrAsp: 1.924 ± 0.042	2.183TyrGlu: 2.183 ± 0.045	1.437TyrPhe: 1.437 ± 0.033	2.686TyrGly: 2.686 ± 0.042	0.607TyrHis: 0.607 ± 0.028	1.717TyrIle: 1.717 ± 0.036	1.458TyrLys: 1.458 ± 0.037	3.068TyrLeu: 3.068 ± 0.047	0.757TyrMet: 0.757 ± 0.025	1.238TyrAsn: 1.238 ± 0.039	1.535TyrPro: 1.535 ± 0.036	0.96TyrGln: 0.96 ± 0.029	2.283TyrArg: 2.283 ± 0.04	2.257TyrSer: 2.257 ± 0.043	1.737TyrThr: 1.737 ± 0.05	2.259TyrVal: 2.259 ± 0.043	0.426TyrTrp: 0.426 ± 0.019	1.341TyrTyr: 1.341 ± 0.035	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5209 proteins (1609417 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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