Amino acid dipepetide frequency for Glycine soja (Wild soybean)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.911AlaAla: 5.911 ± 0.023	1.234AlaCys: 1.234 ± 0.007	2.948AlaAsp: 2.948 ± 0.01	4.065AlaGlu: 4.065 ± 0.014	2.715AlaPhe: 2.715 ± 0.01	3.731AlaGly: 3.731 ± 0.013	1.31AlaHis: 1.31 ± 0.007	3.709AlaIle: 3.709 ± 0.012	3.853AlaLys: 3.853 ± 0.013	6.483AlaLeu: 6.483 ± 0.019	1.689AlaMet: 1.689 ± 0.008	2.695AlaAsn: 2.695 ± 0.01	2.795AlaPro: 2.795 ± 0.01	2.115AlaGln: 2.115 ± 0.01	3.217AlaArg: 3.217 ± 0.011	5.996AlaSer: 5.996 ± 0.015	3.631AlaThr: 3.631 ± 0.013	4.606AlaVal: 4.606 ± 0.015	0.75AlaTrp: 0.75 ± 0.005	1.779AlaTyr: 1.779 ± 0.008	0.0AlaXaa: 0.0 ± 0.0
Cys	0.997CysAla: 0.997 ± 0.005	0.559CysCys: 0.559 ± 0.005	0.918CysAsp: 0.918 ± 0.006	0.908CysGlu: 0.908 ± 0.006	0.946CysPhe: 0.946 ± 0.006	1.362CysGly: 1.362 ± 0.008	0.525CysHis: 0.525 ± 0.004	1.031CysIle: 1.031 ± 0.006	1.149CysLys: 1.149 ± 0.007	1.885CysLeu: 1.885 ± 0.008	0.472CysMet: 0.472 ± 0.004	0.891CysAsn: 0.891 ± 0.006	0.919CysPro: 0.919 ± 0.006	0.645CysGln: 0.645 ± 0.004	0.994CysArg: 0.994 ± 0.006	1.833CysSer: 1.833 ± 0.008	0.882CysThr: 0.882 ± 0.007	1.13CysVal: 1.13 ± 0.006	0.265CysTrp: 0.265 ± 0.003	0.572CysTyr: 0.572 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	3.463AspAla: 3.463 ± 0.012	0.932AspCys: 0.932 ± 0.006	3.678AspAsp: 3.678 ± 0.015	3.828AspGlu: 3.828 ± 0.013	2.326AspPhe: 2.326 ± 0.008	3.648AspGly: 3.648 ± 0.013	1.281AspHis: 1.281 ± 0.007	3.078AspIle: 3.078 ± 0.011	2.831AspLys: 2.831 ± 0.009	5.064AspLeu: 5.064 ± 0.012	1.305AspMet: 1.305 ± 0.006	2.295AspAsn: 2.295 ± 0.009	2.561AspPro: 2.561 ± 0.009	1.798AspGln: 1.798 ± 0.008	2.288AspArg: 2.288 ± 0.01	4.312AspSer: 4.312 ± 0.014	2.3AspThr: 2.3 ± 0.01	3.596AspVal: 3.596 ± 0.012	0.692AspTrp: 0.692 ± 0.005	1.538AspTyr: 1.538 ± 0.007	0.0AspXaa: 0.0 ± 0.0
Glu	4.627GluAla: 4.627 ± 0.016	0.955GluCys: 0.955 ± 0.007	3.925GluAsp: 3.925 ± 0.013	6.089GluGlu: 6.089 ± 0.024	2.351GluPhe: 2.351 ± 0.008	3.689GluGly: 3.689 ± 0.011	1.331GluHis: 1.331 ± 0.007	3.733GluIle: 3.733 ± 0.012	4.753GluLys: 4.753 ± 0.015	5.837GluLeu: 5.837 ± 0.016	1.652GluMet: 1.652 ± 0.008	3.267GluAsn: 3.267 ± 0.011	2.093GluPro: 2.093 ± 0.009	2.202GluGln: 2.202 ± 0.01	3.303GluArg: 3.303 ± 0.013	4.581GluSer: 4.581 ± 0.013	3.042GluThr: 3.042 ± 0.012	4.144GluVal: 4.144 ± 0.012	0.728GluTrp: 0.728 ± 0.005	1.671GluTyr: 1.671 ± 0.008	0.0GluXaa: 0.0 ± 0.0
Phe	2.455PheAla: 2.455 ± 0.01	0.949PheCys: 0.949 ± 0.006	2.312PheAsp: 2.312 ± 0.009	2.277PheGlu: 2.277 ± 0.008	2.009PhePhe: 2.009 ± 0.01	3.044PheGly: 3.044 ± 0.011	1.191PheHis: 1.191 ± 0.006	2.106PheIle: 2.106 ± 0.008	2.155PheLys: 2.155 ± 0.009	4.381PheLeu: 4.381 ± 0.015	0.968PheMet: 0.968 ± 0.005	1.831PheAsn: 1.831 ± 0.007	2.168PhePro: 2.168 ± 0.01	1.599PheGln: 1.599 ± 0.007	2.022PheArg: 2.022 ± 0.009	4.161PheSer: 4.161 ± 0.012	1.983PheThr: 1.983 ± 0.008	2.807PheVal: 2.807 ± 0.011	0.57PheTrp: 0.57 ± 0.004	1.297PheTyr: 1.297 ± 0.006	0.0PheXaa: 0.0 ± 0.0
Gly	3.692GlyAla: 3.692 ± 0.013	1.265GlyCys: 1.265 ± 0.007	3.293GlyAsp: 3.293 ± 0.011	3.556GlyGlu: 3.556 ± 0.012	3.029GlyPhe: 3.029 ± 0.01	5.143GlyGly: 5.143 ± 0.034	1.581GlyHis: 1.581 ± 0.008	3.575GlyIle: 3.575 ± 0.012	4.058GlyLys: 4.058 ± 0.013	5.701GlyLeu: 5.701 ± 0.015	1.479GlyMet: 1.479 ± 0.007	3.216GlyAsn: 3.216 ± 0.011	2.362GlyPro: 2.362 ± 0.009	2.07GlyGln: 2.07 ± 0.01	3.341GlyArg: 3.341 ± 0.012	5.928GlySer: 5.928 ± 0.016	3.227GlyThr: 3.227 ± 0.011	4.136GlyVal: 4.136 ± 0.014	0.881GlyTrp: 0.881 ± 0.005	2.038GlyTyr: 2.038 ± 0.009	0.0GlyXaa: 0.0 ± 0.0
His	1.55HisAla: 1.55 ± 0.007	0.544HisCys: 0.544 ± 0.004	1.243HisAsp: 1.243 ± 0.007	1.374HisGlu: 1.374 ± 0.007	1.148HisPhe: 1.148 ± 0.006	1.738HisGly: 1.738 ± 0.007	1.086HisHis: 1.086 ± 0.008	1.284HisIle: 1.284 ± 0.007	1.281HisLys: 1.281 ± 0.006	2.517HisLeu: 2.517 ± 0.01	0.597HisMet: 0.597 ± 0.005	1.148HisAsn: 1.148 ± 0.006	1.406HisPro: 1.406 ± 0.008	1.11HisGln: 1.11 ± 0.007	1.399HisArg: 1.399 ± 0.007	2.156HisSer: 2.156 ± 0.009	1.071HisThr: 1.071 ± 0.006	1.702HisVal: 1.702 ± 0.008	0.327HisTrp: 0.327 ± 0.003	0.75HisTyr: 0.75 ± 0.005	0.0HisXaa: 0.0 ± 0.0
Ile	3.549IleAla: 3.549 ± 0.013	1.119IleCys: 1.119 ± 0.006	2.889IleAsp: 2.889 ± 0.01	3.18IleGlu: 3.18 ± 0.01	2.316IlePhe: 2.316 ± 0.009	3.388IleGly: 3.388 ± 0.012	1.361IleHis: 1.361 ± 0.006	2.912IleIle: 2.912 ± 0.012	3.008IleLys: 3.008 ± 0.011	5.333IleLeu: 5.333 ± 0.017	1.183IleMet: 1.183 ± 0.006	2.325IleAsn: 2.325 ± 0.009	3.006IlePro: 3.006 ± 0.014	2.088IleGln: 2.088 ± 0.01	2.541IleArg: 2.541 ± 0.008	4.8IleSer: 4.8 ± 0.013	2.631IleThr: 2.631 ± 0.01	3.514IleVal: 3.514 ± 0.011	0.706IleTrp: 0.706 ± 0.005	1.505IleTyr: 1.505 ± 0.008	0.0IleXaa: 0.0 ± 0.0
Lys	3.914LysAla: 3.914 ± 0.011	0.99LysCys: 0.99 ± 0.005	3.348LysAsp: 3.348 ± 0.012	4.724LysGlu: 4.724 ± 0.015	2.248LysPhe: 2.248 ± 0.01	3.745LysGly: 3.745 ± 0.012	1.488LysHis: 1.488 ± 0.007	3.327LysIle: 3.327 ± 0.012	4.707LysLys: 4.707 ± 0.02	6.07LysLeu: 6.07 ± 0.017	1.474LysMet: 1.474 ± 0.007	2.822LysAsn: 2.822 ± 0.011	2.736LysPro: 2.736 ± 0.012	2.358LysGln: 2.358 ± 0.01	3.535LysArg: 3.535 ± 0.011	4.766LysSer: 4.766 ± 0.015	2.94LysThr: 2.94 ± 0.01	4.011LysVal: 4.011 ± 0.011	0.819LysTrp: 0.819 ± 0.004	1.671LysTyr: 1.671 ± 0.006	0.0LysXaa: 0.0 ± 0.0
Leu	6.338LeuAla: 6.338 ± 0.013	1.931LeuCys: 1.931 ± 0.008	5.149LeuAsp: 5.149 ± 0.014	6.311LeuGlu: 6.311 ± 0.02	3.944LeuPhe: 3.944 ± 0.014	5.649LeuGly: 5.649 ± 0.016	2.757LeuHis: 2.757 ± 0.011	4.57LeuIle: 4.57 ± 0.014	6.296LeuLys: 6.296 ± 0.017	10.012LeuLeu: 10.012 ± 0.024	2.114LeuMet: 2.114 ± 0.009	4.213LeuAsn: 4.213 ± 0.013	5.135LeuPro: 5.135 ± 0.015	4.438LeuGln: 4.438 ± 0.013	5.298LeuArg: 5.298 ± 0.015	8.821LeuSer: 8.821 ± 0.023	4.507LeuThr: 4.507 ± 0.013	6.364LeuVal: 6.364 ± 0.015	1.211LeuTrp: 1.211 ± 0.007	2.555LeuTyr: 2.555 ± 0.01	0.0LeuXaa: 0.0 ± 0.0
Met	1.977MetAla: 1.977 ± 0.008	0.355MetCys: 0.355 ± 0.003	1.407MetAsp: 1.407 ± 0.007	1.906MetGlu: 1.906 ± 0.009	0.827MetPhe: 0.827 ± 0.005	1.565MetGly: 1.565 ± 0.008	0.6MetHis: 0.6 ± 0.005	1.158MetIle: 1.158 ± 0.006	1.626MetLys: 1.626 ± 0.008	2.284MetLeu: 2.284 ± 0.01	0.687MetMet: 0.687 ± 0.005	1.047MetAsn: 1.047 ± 0.006	1.079MetPro: 1.079 ± 0.007	0.99MetGln: 0.99 ± 0.006	1.154MetArg: 1.154 ± 0.006	1.817MetSer: 1.817 ± 0.008	1.054MetThr: 1.054 ± 0.006	1.631MetVal: 1.631 ± 0.006	0.277MetTrp: 0.277 ± 0.003	0.577MetTyr: 0.577 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.81AsnAla: 2.81 ± 0.009	0.907AsnCys: 0.907 ± 0.005	2.293AsnAsp: 2.293 ± 0.009	2.707AsnGlu: 2.707 ± 0.01	2.065AsnPhe: 2.065 ± 0.009	3.288AsnGly: 3.288 ± 0.012	1.245AsnHis: 1.245 ± 0.007	2.662AsnIle: 2.662 ± 0.01	2.685AsnLys: 2.685 ± 0.008	4.833AsnLeu: 4.833 ± 0.018	1.223AsnMet: 1.223 ± 0.006	2.88AsnAsn: 2.88 ± 0.016	2.341AsnPro: 2.341 ± 0.009	1.833AsnGln: 1.833 ± 0.009	2.012AsnArg: 2.012 ± 0.009	4.189AsnSer: 4.189 ± 0.013	2.137AsnThr: 2.137 ± 0.01	2.992AsnVal: 2.992 ± 0.01	0.601AsnTrp: 0.601 ± 0.004	1.377AsnTyr: 1.377 ± 0.006	0.0AsnXaa: 0.0 ± 0.0
Pro	2.848ProAla: 2.848 ± 0.013	0.792ProCys: 0.792 ± 0.006	2.335ProAsp: 2.335 ± 0.008	2.992ProGlu: 2.992 ± 0.011	2.068ProPhe: 2.068 ± 0.009	2.554ProGly: 2.554 ± 0.011	1.216ProHis: 1.216 ± 0.006	2.362ProIle: 2.362 ± 0.009	2.775ProLys: 2.775 ± 0.011	4.459ProLeu: 4.459 ± 0.014	0.974ProMet: 0.974 ± 0.006	2.438ProAsn: 2.438 ± 0.01	4.018ProPro: 4.018 ± 0.043	1.912ProGln: 1.912 ± 0.011	2.307ProArg: 2.307 ± 0.009	5.27ProSer: 5.27 ± 0.018	2.64ProThr: 2.64 ± 0.01	3.003ProVal: 3.003 ± 0.011	0.592ProTrp: 0.592 ± 0.005	1.346ProTyr: 1.346 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	2.317GlnAla: 2.317 ± 0.009	0.636GlnCys: 0.636 ± 0.004	1.725GlnAsp: 1.725 ± 0.007	2.462GlnGlu: 2.462 ± 0.01	1.443GlnPhe: 1.443 ± 0.007	2.154GlnGly: 2.154 ± 0.009	1.087GlnHis: 1.087 ± 0.007	2.058GlnIle: 2.058 ± 0.008	2.442GlnLys: 2.442 ± 0.009	3.761GlnLeu: 3.761 ± 0.012	0.988GlnMet: 0.988 ± 0.006	1.982GlnAsn: 1.982 ± 0.009	1.81GlnPro: 1.81 ± 0.01	2.285GlnGln: 2.285 ± 0.019	2.115GlnArg: 2.115 ± 0.008	2.979GlnSer: 2.979 ± 0.011	1.811GlnThr: 1.811 ± 0.008	2.413GlnVal: 2.413 ± 0.008	0.482GlnTrp: 0.482 ± 0.004	0.986GlnTyr: 0.986 ± 0.006	0.0GlnXaa: 0.0 ± 0.0
Arg	3.035ArgAla: 3.035 ± 0.011	0.947ArgCys: 0.947 ± 0.005	2.62ArgAsp: 2.62 ± 0.009	3.234ArgGlu: 3.234 ± 0.013	2.144ArgPhe: 2.144 ± 0.008	3.067ArgGly: 3.067 ± 0.014	1.323ArgHis: 1.323 ± 0.007	2.788ArgIle: 2.788 ± 0.009	3.713ArgLys: 3.713 ± 0.012	4.792ArgLeu: 4.792 ± 0.014	1.273ArgMet: 1.273 ± 0.006	2.482ArgAsn: 2.482 ± 0.009	2.199ArgPro: 2.199 ± 0.009	1.823ArgGln: 1.823 ± 0.008	3.662ArgArg: 3.662 ± 0.015	4.159ArgSer: 4.159 ± 0.014	2.382ArgThr: 2.382 ± 0.008	3.293ArgVal: 3.293 ± 0.011	0.723ArgTrp: 0.723 ± 0.005	1.412ArgTyr: 1.412 ± 0.008	0.0ArgXaa: 0.0 ± 0.0
Ser	5.221SerAla: 5.221 ± 0.015	1.73SerCys: 1.73 ± 0.008	4.49SerAsp: 4.49 ± 0.013	4.886SerGlu: 4.886 ± 0.016	4.027SerPhe: 4.027 ± 0.013	5.788SerGly: 5.788 ± 0.017	2.238SerHis: 2.238 ± 0.01	4.597SerIle: 4.597 ± 0.012	5.081SerLys: 5.081 ± 0.014	8.958SerLeu: 8.958 ± 0.023	2.111SerMet: 2.111 ± 0.009	4.459SerAsn: 4.459 ± 0.013	4.599SerPro: 4.599 ± 0.025	3.239SerGln: 3.239 ± 0.013	4.276SerArg: 4.276 ± 0.014	11.07SerSer: 11.07 ± 0.03	4.718SerThr: 4.718 ± 0.013	5.324SerVal: 5.324 ± 0.015	1.157SerTrp: 1.157 ± 0.007	2.352SerTyr: 2.352 ± 0.008	0.0SerXaa: 0.0 ± 0.0
Thr	3.207ThrAla: 3.207 ± 0.011	0.969ThrCys: 0.969 ± 0.006	2.241ThrAsp: 2.241 ± 0.009	2.767ThrGlu: 2.767 ± 0.011	2.092ThrPhe: 2.092 ± 0.009	3.107ThrGly: 3.107 ± 0.01	1.139ThrHis: 1.139 ± 0.006	2.801ThrIle: 2.801 ± 0.009	2.829ThrLys: 2.829 ± 0.01	4.878ThrLeu: 4.878 ± 0.012	1.198ThrMet: 1.198 ± 0.006	2.308ThrAsn: 2.308 ± 0.009	2.653ThrPro: 2.653 ± 0.011	1.637ThrGln: 1.637 ± 0.007	2.345ThrArg: 2.345 ± 0.008	4.666ThrSer: 4.666 ± 0.013	3.164ThrThr: 3.164 ± 0.013	3.269ThrVal: 3.269 ± 0.01	0.658ThrTrp: 0.658 ± 0.004	1.382ThrTyr: 1.382 ± 0.008	0.0ThrXaa: 0.0 ± 0.0
Val	4.833ValAla: 4.833 ± 0.014	1.182ValCys: 1.182 ± 0.007	3.717ValAsp: 3.717 ± 0.011	4.352ValGlu: 4.352 ± 0.013	2.71ValPhe: 2.71 ± 0.01	4.093ValGly: 4.093 ± 0.014	1.581ValHis: 1.581 ± 0.007	3.404ValIle: 3.404 ± 0.011	3.907ValLys: 3.907 ± 0.012	6.337ValLeu: 6.337 ± 0.016	1.531ValMet: 1.531 ± 0.007	2.728ValAsn: 2.728 ± 0.009	3.23ValPro: 3.23 ± 0.011	2.361ValGln: 2.361 ± 0.01	3.016ValArg: 3.016 ± 0.011	5.56ValSer: 5.56 ± 0.014	3.286ValThr: 3.286 ± 0.012	5.035ValVal: 5.035 ± 0.016	0.771ValTrp: 0.771 ± 0.005	1.928ValTyr: 1.928 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.718TrpAla: 0.718 ± 0.005	0.248TrpCys: 0.248 ± 0.003	0.718TrpAsp: 0.718 ± 0.005	0.761TrpGlu: 0.761 ± 0.005	0.574TrpPhe: 0.574 ± 0.004	0.727TrpGly: 0.727 ± 0.005	0.316TrpHis: 0.316 ± 0.003	0.71TrpIle: 0.71 ± 0.005	0.974TrpLys: 0.974 ± 0.006	1.249TrpLeu: 1.249 ± 0.007	0.347TrpMet: 0.347 ± 0.003	0.71TrpAsn: 0.71 ± 0.005	0.51TrpPro: 0.51 ± 0.005	0.463TrpGln: 0.463 ± 0.004	0.823TrpArg: 0.823 ± 0.006	0.988TrpSer: 0.988 ± 0.005	0.621TrpThr: 0.621 ± 0.004	0.802TrpVal: 0.802 ± 0.006	0.263TrpTrp: 0.263 ± 0.003	0.347TrpTyr: 0.347 ± 0.003	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.769TyrAla: 1.769 ± 0.008	0.64TyrCys: 0.64 ± 0.005	1.564TyrAsp: 1.564 ± 0.008	1.595TyrGlu: 1.595 ± 0.007	1.305TyrPhe: 1.305 ± 0.007	2.091TyrGly: 2.091 ± 0.009	0.778TyrHis: 0.778 ± 0.005	1.487TyrIle: 1.487 ± 0.008	1.566TyrLys: 1.566 ± 0.01	2.776TyrLeu: 2.776 ± 0.01	0.753TyrMet: 0.753 ± 0.005	1.346TyrAsn: 1.346 ± 0.007	1.281TyrPro: 1.281 ± 0.007	0.968TyrGln: 0.968 ± 0.006	1.422TyrArg: 1.422 ± 0.007	2.27TyrSer: 2.27 ± 0.008	1.283TyrThr: 1.283 ± 0.007	1.79TyrVal: 1.79 ± 0.008	0.395TyrTrp: 0.395 ± 0.004	0.997TyrTyr: 0.997 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 75060 proteins (32485611 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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