Amino acid dipepetide frequency for Actinidia virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.469AlaAla: 4.469 ± 1.129
0.993AlaCys: 0.993 ± 0.344
3.145AlaAsp: 3.145 ± 0.385
4.138AlaGlu: 4.138 ± 0.826
1.821AlaPhe: 1.821 ± 0.543
1.986AlaGly: 1.986 ± 0.467
1.159AlaHis: 1.159 ± 0.327
4.138AlaIle: 4.138 ± 0.851
2.98AlaLys: 2.98 ± 0.599
7.449AlaLeu: 7.449 ± 0.892
1.159AlaMet: 1.159 ± 0.409
3.145AlaAsn: 3.145 ± 0.665
2.483AlaPro: 2.483 ± 0.535
1.324AlaGln: 1.324 ± 0.625
2.317AlaArg: 2.317 ± 0.937
4.469AlaSer: 4.469 ± 0.896
2.814AlaThr: 2.814 ± 0.746
6.787AlaVal: 6.787 ± 1.671
0.0AlaTrp: 0.0 ± 0.0
3.145AlaTyr: 3.145 ± 0.55
0.0AlaXaa: 0.0 ± 0.0
Cys
0.497CysAla: 0.497 ± 0.247
0.497CysCys: 0.497 ± 0.244
1.159CysAsp: 1.159 ± 0.418
1.159CysGlu: 1.159 ± 0.472
0.993CysPhe: 0.993 ± 0.373
0.662CysGly: 0.662 ± 0.342
0.828CysHis: 0.828 ± 0.398
1.159CysIle: 1.159 ± 0.355
1.159CysLys: 1.159 ± 0.572
1.986CysLeu: 1.986 ± 0.944
0.828CysMet: 0.828 ± 0.475
1.159CysAsn: 1.159 ± 0.766
1.49CysPro: 1.49 ± 0.658
0.993CysGln: 0.993 ± 0.283
0.993CysArg: 0.993 ± 0.389
2.814CysSer: 2.814 ± 0.94
0.662CysThr: 0.662 ± 0.419
1.324CysVal: 1.324 ± 0.426
0.0CysTrp: 0.0 ± 0.0
1.986CysTyr: 1.986 ± 0.519
0.0CysXaa: 0.0 ± 0.0
Asp
2.98AspAla: 2.98 ± 0.749
0.662AspCys: 0.662 ± 0.269
3.311AspAsp: 3.311 ± 0.841
2.483AspGlu: 2.483 ± 0.634
3.476AspPhe: 3.476 ± 0.907
2.317AspGly: 2.317 ± 0.641
1.324AspHis: 1.324 ± 0.603
3.311AspIle: 3.311 ± 0.568
2.814AspLys: 2.814 ± 1.15
5.297AspLeu: 5.297 ± 1.162
2.152AspMet: 2.152 ± 0.677
2.814AspAsn: 2.814 ± 0.668
1.986AspPro: 1.986 ± 0.55
0.993AspGln: 0.993 ± 0.294
3.311AspArg: 3.311 ± 0.641
4.966AspSer: 4.966 ± 0.686
2.98AspThr: 2.98 ± 0.577
6.787AspVal: 6.787 ± 0.977
1.49AspTrp: 1.49 ± 0.58
2.483AspTyr: 2.483 ± 1.104
0.0AspXaa: 0.0 ± 0.0
Glu
2.98GluAla: 2.98 ± 0.874
1.159GluCys: 1.159 ± 0.553
1.821GluAsp: 1.821 ± 0.608
1.986GluGlu: 1.986 ± 1.008
1.655GluPhe: 1.655 ± 0.549
2.317GluGly: 2.317 ± 0.721
0.662GluHis: 0.662 ± 0.29
3.311GluIle: 3.311 ± 0.419
2.152GluLys: 2.152 ± 0.749
4.801GluLeu: 4.801 ± 0.786
1.655GluMet: 1.655 ± 0.508
2.649GluAsn: 2.649 ± 0.731
1.324GluPro: 1.324 ± 0.327
1.324GluGln: 1.324 ± 0.366
4.635GluArg: 4.635 ± 1.164
3.642GluSer: 3.642 ± 1.029
2.483GluThr: 2.483 ± 0.66
3.476GluVal: 3.476 ± 0.628
0.662GluTrp: 0.662 ± 0.311
1.821GluTyr: 1.821 ± 0.495
0.0GluXaa: 0.0 ± 0.0
Phe
1.655PheAla: 1.655 ± 1.35
1.159PheCys: 1.159 ± 0.928
3.145PheAsp: 3.145 ± 1.118
2.483PheGlu: 2.483 ± 0.718
3.145PhePhe: 3.145 ± 0.636
2.98PheGly: 2.98 ± 0.51
0.331PheHis: 0.331 ± 0.297
1.821PheIle: 1.821 ± 0.585
2.98PheLys: 2.98 ± 0.757
4.635PheLeu: 4.635 ± 0.951
1.324PheMet: 1.324 ± 0.473
1.986PheAsn: 1.986 ± 0.516
1.159PhePro: 1.159 ± 0.473
0.662PheGln: 0.662 ± 0.586
3.311PheArg: 3.311 ± 0.608
4.801PheSer: 4.801 ± 1.03
1.49PheThr: 1.49 ± 0.469
1.655PheVal: 1.655 ± 0.509
0.331PheTrp: 0.331 ± 0.416
0.828PheTyr: 0.828 ± 0.387
0.0PheXaa: 0.0 ± 0.0
Gly
4.304GlyAla: 4.304 ± 1.093
0.993GlyCys: 0.993 ± 0.432
3.642GlyAsp: 3.642 ± 0.681
2.814GlyGlu: 2.814 ± 0.749
1.324GlyPhe: 1.324 ± 0.704
5.628GlyGly: 5.628 ± 0.832
0.993GlyHis: 0.993 ± 0.431
1.821GlyIle: 1.821 ± 1.341
3.807GlyLys: 3.807 ± 0.809
3.973GlyLeu: 3.973 ± 0.936
0.662GlyMet: 0.662 ± 0.617
2.814GlyAsn: 2.814 ± 0.647
1.655GlyPro: 1.655 ± 0.516
0.993GlyGln: 0.993 ± 0.45
4.635GlyArg: 4.635 ± 1.653
4.635GlySer: 4.635 ± 1.027
3.807GlyThr: 3.807 ± 1.075
3.476GlyVal: 3.476 ± 0.607
1.159GlyTrp: 1.159 ± 0.704
3.145GlyTyr: 3.145 ± 0.555
0.0GlyXaa: 0.0 ± 0.0
His
0.662HisAla: 0.662 ± 0.306
0.166HisCys: 0.166 ± 0.245
1.986HisAsp: 1.986 ± 0.781
0.828HisGlu: 0.828 ± 0.317
0.662HisPhe: 0.662 ± 0.274
0.828HisGly: 0.828 ± 0.243
0.331HisHis: 0.331 ± 0.179
1.159HisIle: 1.159 ± 0.333
0.993HisLys: 0.993 ± 0.39
2.649HisLeu: 2.649 ± 0.942
0.331HisMet: 0.331 ± 0.197
0.993HisAsn: 0.993 ± 0.379
0.662HisPro: 0.662 ± 0.457
0.662HisGln: 0.662 ± 0.291
0.828HisArg: 0.828 ± 0.503
1.986HisSer: 1.986 ± 0.533
1.49HisThr: 1.49 ± 0.528
1.159HisVal: 1.159 ± 0.368
0.331HisTrp: 0.331 ± 0.371
0.828HisTyr: 0.828 ± 0.359
0.0HisXaa: 0.0 ± 0.0
Ile
2.483IleAla: 2.483 ± 0.827
0.828IleCys: 0.828 ± 0.303
3.642IleAsp: 3.642 ± 0.504
2.152IleGlu: 2.152 ± 0.675
2.317IlePhe: 2.317 ± 0.798
4.138IleGly: 4.138 ± 0.88
0.993IleHis: 0.993 ± 0.456
5.297IleIle: 5.297 ± 2.067
3.311IleLys: 3.311 ± 1.005
6.125IleLeu: 6.125 ± 0.619
1.324IleMet: 1.324 ± 0.587
2.649IleAsn: 2.649 ± 0.708
3.973IlePro: 3.973 ± 0.996
0.497IleGln: 0.497 ± 0.255
4.635IleArg: 4.635 ± 0.889
5.794IleSer: 5.794 ± 1.413
4.635IleThr: 4.635 ± 1.384
4.469IleVal: 4.469 ± 0.82
0.0IleTrp: 0.0 ± 0.0
3.311IleTyr: 3.311 ± 1.331
0.0IleXaa: 0.0 ± 0.0
Lys
3.973LysAla: 3.973 ± 0.786
0.331LysCys: 0.331 ± 0.208
3.642LysAsp: 3.642 ± 0.762
1.49LysGlu: 1.49 ± 0.579
2.649LysPhe: 2.649 ± 1.622
3.311LysGly: 3.311 ± 0.576
1.986LysHis: 1.986 ± 0.638
3.807LysIle: 3.807 ± 0.872
4.138LysLys: 4.138 ± 0.857
4.966LysLeu: 4.966 ± 1.58
0.993LysMet: 0.993 ± 0.601
2.649LysAsn: 2.649 ± 0.745
3.311LysPro: 3.311 ± 0.894
0.993LysGln: 0.993 ± 0.603
3.973LysArg: 3.973 ± 0.988
3.973LysSer: 3.973 ± 0.631
3.311LysThr: 3.311 ± 0.697
5.132LysVal: 5.132 ± 0.901
0.331LysTrp: 0.331 ± 0.198
3.311LysTyr: 3.311 ± 1.409
0.0LysXaa: 0.0 ± 0.0
Leu
3.642LeuAla: 3.642 ± 0.74
1.986LeuCys: 1.986 ± 0.967
5.794LeuAsp: 5.794 ± 1.255
3.145LeuGlu: 3.145 ± 0.815
4.801LeuPhe: 4.801 ± 0.519
5.959LeuGly: 5.959 ± 1.063
2.152LeuHis: 2.152 ± 0.546
5.132LeuIle: 5.132 ± 1.59
4.966LeuLys: 4.966 ± 0.886
8.773LeuLeu: 8.773 ± 1.847
2.98LeuMet: 2.98 ± 0.579
5.463LeuAsn: 5.463 ± 0.739
3.145LeuPro: 3.145 ± 0.58
1.324LeuGln: 1.324 ± 0.591
5.959LeuArg: 5.959 ± 1.04
8.111LeuSer: 8.111 ± 1.51
5.463LeuThr: 5.463 ± 0.741
9.104LeuVal: 9.104 ± 1.791
0.828LeuTrp: 0.828 ± 0.338
4.635LeuTyr: 4.635 ± 1.09
0.0LeuXaa: 0.0 ± 0.0
Met
1.49MetAla: 1.49 ± 0.576
0.662MetCys: 0.662 ± 0.224
1.324MetAsp: 1.324 ± 0.462
0.993MetGlu: 0.993 ± 0.528
0.662MetPhe: 0.662 ± 0.222
0.828MetGly: 0.828 ± 0.4
0.331MetHis: 0.331 ± 0.201
0.828MetIle: 0.828 ± 0.578
0.993MetLys: 0.993 ± 0.308
2.98MetLeu: 2.98 ± 0.974
0.166MetMet: 0.166 ± 0.203
1.159MetAsn: 1.159 ± 0.296
0.497MetPro: 0.497 ± 0.238
0.331MetGln: 0.331 ± 0.303
1.324MetArg: 1.324 ± 0.479
2.98MetSer: 2.98 ± 1.327
1.821MetThr: 1.821 ± 0.494
2.649MetVal: 2.649 ± 0.772
0.331MetTrp: 0.331 ± 0.198
1.49MetTyr: 1.49 ± 0.683
0.0MetXaa: 0.0 ± 0.0
Asn
2.152AsnAla: 2.152 ± 0.331
1.49AsnCys: 1.49 ± 0.572
2.98AsnAsp: 2.98 ± 0.703
3.145AsnGlu: 3.145 ± 0.605
2.152AsnPhe: 2.152 ± 0.497
1.986AsnGly: 1.986 ± 0.663
0.497AsnHis: 0.497 ± 0.506
4.469AsnIle: 4.469 ± 0.869
3.311AsnLys: 3.311 ± 1.308
3.807AsnLeu: 3.807 ± 0.743
1.655AsnMet: 1.655 ± 0.526
2.649AsnAsn: 2.649 ± 0.924
2.483AsnPro: 2.483 ± 0.471
0.828AsnGln: 0.828 ± 0.395
2.98AsnArg: 2.98 ± 0.68
4.469AsnSer: 4.469 ± 0.789
2.483AsnThr: 2.483 ± 0.839
3.807AsnVal: 3.807 ± 0.844
0.331AsnTrp: 0.331 ± 0.531
2.152AsnTyr: 2.152 ± 0.897
0.0AsnXaa: 0.0 ± 0.0
Pro
3.807ProAla: 3.807 ± 1.696
0.828ProCys: 0.828 ± 0.26
2.317ProAsp: 2.317 ± 1.112
2.152ProGlu: 2.152 ± 0.785
1.324ProPhe: 1.324 ± 0.459
2.483ProGly: 2.483 ± 1.037
0.331ProHis: 0.331 ± 0.189
3.311ProIle: 3.311 ± 0.88
3.145ProLys: 3.145 ± 0.763
2.814ProLeu: 2.814 ± 0.611
0.828ProMet: 0.828 ± 0.375
1.49ProAsn: 1.49 ± 0.308
2.814ProPro: 2.814 ± 1.126
0.662ProGln: 0.662 ± 0.291
1.49ProArg: 1.49 ± 0.595
2.814ProSer: 2.814 ± 0.683
1.655ProThr: 1.655 ± 0.238
3.973ProVal: 3.973 ± 1.336
0.166ProTrp: 0.166 ± 0.227
1.159ProTyr: 1.159 ± 0.446
0.0ProXaa: 0.0 ± 0.0
Gln
1.821GlnAla: 1.821 ± 0.587
0.331GlnCys: 0.331 ± 0.228
1.49GlnAsp: 1.49 ± 0.529
0.662GlnGlu: 0.662 ± 0.416
0.497GlnPhe: 0.497 ± 0.447
1.655GlnGly: 1.655 ± 0.35
0.828GlnHis: 0.828 ± 0.278
1.821GlnIle: 1.821 ± 0.863
0.993GlnLys: 0.993 ± 0.537
2.814GlnLeu: 2.814 ± 0.561
0.166GlnMet: 0.166 ± 0.101
0.828GlnAsn: 0.828 ± 0.243
0.497GlnPro: 0.497 ± 0.216
0.331GlnGln: 0.331 ± 0.303
1.49GlnArg: 1.49 ± 0.338
1.655GlnSer: 1.655 ± 0.397
0.497GlnThr: 0.497 ± 0.228
1.159GlnVal: 1.159 ± 0.462
0.0GlnTrp: 0.0 ± 0.0
0.993GlnTyr: 0.993 ± 0.276
0.0GlnXaa: 0.0 ± 0.0
Arg
4.966ArgAla: 4.966 ± 1.567
2.152ArgCys: 2.152 ± 0.578
2.98ArgAsp: 2.98 ± 1.155
3.145ArgGlu: 3.145 ± 1.099
2.814ArgPhe: 2.814 ± 0.651
3.145ArgGly: 3.145 ± 0.942
0.828ArgHis: 0.828 ± 0.622
4.304ArgIle: 4.304 ± 0.948
3.973ArgLys: 3.973 ± 0.705
5.794ArgLeu: 5.794 ± 0.808
1.655ArgMet: 1.655 ± 0.519
3.476ArgAsn: 3.476 ± 0.746
1.821ArgPro: 1.821 ± 0.502
2.152ArgGln: 2.152 ± 0.57
3.973ArgArg: 3.973 ± 1.016
6.125ArgSer: 6.125 ± 0.687
2.814ArgThr: 2.814 ± 0.558
4.304ArgVal: 4.304 ± 1.578
0.828ArgTrp: 0.828 ± 0.26
3.807ArgTyr: 3.807 ± 0.931
0.0ArgXaa: 0.0 ± 0.0
Ser
5.628SerAla: 5.628 ± 0.873
2.814SerCys: 2.814 ± 0.439
4.635SerAsp: 4.635 ± 1.493
4.801SerGlu: 4.801 ± 0.886
3.973SerPhe: 3.973 ± 0.61
5.794SerGly: 5.794 ± 1.29
0.828SerHis: 0.828 ± 0.468
6.29SerIle: 6.29 ± 0.807
6.456SerLys: 6.456 ± 0.691
7.284SerLeu: 7.284 ± 1.466
1.655SerMet: 1.655 ± 0.463
2.649SerAsn: 2.649 ± 1.154
2.649SerPro: 2.649 ± 0.645
2.814SerGln: 2.814 ± 1.118
5.628SerArg: 5.628 ± 1.086
7.946SerSer: 7.946 ± 1.159
3.642SerThr: 3.642 ± 0.874
7.78SerVal: 7.78 ± 1.285
0.828SerTrp: 0.828 ± 0.4
3.311SerTyr: 3.311 ± 1.087
0.0SerXaa: 0.0 ± 0.0
Thr
3.145ThrAla: 3.145 ± 0.575
1.159ThrCys: 1.159 ± 0.504
2.649ThrAsp: 2.649 ± 0.896
2.317ThrGlu: 2.317 ± 0.372
2.152ThrPhe: 2.152 ± 0.398
1.324ThrGly: 1.324 ± 0.412
1.49ThrHis: 1.49 ± 0.534
2.98ThrIle: 2.98 ± 0.669
2.483ThrLys: 2.483 ± 0.971
4.801ThrLeu: 4.801 ± 0.625
1.986ThrMet: 1.986 ± 0.699
2.649ThrAsn: 2.649 ± 0.933
2.317ThrPro: 2.317 ± 0.846
1.324ThrGln: 1.324 ± 0.341
3.807ThrArg: 3.807 ± 0.654
4.304ThrSer: 4.304 ± 2.119
5.463ThrThr: 5.463 ± 1.15
5.297ThrVal: 5.297 ± 0.719
0.331ThrTrp: 0.331 ± 0.208
2.152ThrTyr: 2.152 ± 0.594
0.0ThrXaa: 0.0 ± 0.0
Val
6.621ValAla: 6.621 ± 1.171
2.317ValCys: 2.317 ± 0.577
3.642ValAsp: 3.642 ± 0.575
4.304ValGlu: 4.304 ± 1.583
2.98ValPhe: 2.98 ± 0.862
4.635ValGly: 4.635 ± 0.97
1.986ValHis: 1.986 ± 0.8
4.138ValIle: 4.138 ± 1.503
5.463ValLys: 5.463 ± 0.855
6.787ValLeu: 6.787 ± 1.33
1.324ValMet: 1.324 ± 0.632
4.635ValAsn: 4.635 ± 0.966
2.814ValPro: 2.814 ± 1.146
1.821ValGln: 1.821 ± 0.569
4.966ValArg: 4.966 ± 1.532
8.111ValSer: 8.111 ± 1.797
4.635ValThr: 4.635 ± 0.883
7.449ValVal: 7.449 ± 1.324
0.662ValTrp: 0.662 ± 0.291
4.138ValTyr: 4.138 ± 1.106
0.0ValXaa: 0.0 ± 0.0
Trp
0.331TrpAla: 0.331 ± 0.201
0.166TrpCys: 0.166 ± 0.245
0.331TrpAsp: 0.331 ± 0.208
0.662TrpGlu: 0.662 ± 0.402
0.662TrpPhe: 0.662 ± 0.29
0.993TrpGly: 0.993 ± 0.399
0.166TrpHis: 0.166 ± 0.288
0.166TrpIle: 0.166 ± 0.101
0.166TrpLys: 0.166 ± 0.191
1.324TrpLeu: 1.324 ± 0.566
0.166TrpMet: 0.166 ± 0.101
0.497TrpAsn: 0.497 ± 0.244
0.662TrpPro: 0.662 ± 0.283
0.166TrpGln: 0.166 ± 0.101
0.497TrpArg: 0.497 ± 0.308
0.497TrpSer: 0.497 ± 0.212
0.331TrpThr: 0.331 ± 0.228
0.993TrpVal: 0.993 ± 0.279
0.0TrpTrp: 0.0 ± 0.0
0.497TrpTyr: 0.497 ± 0.271
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.317TyrAla: 2.317 ± 0.741
1.655TyrCys: 1.655 ± 0.531
4.304TyrAsp: 4.304 ± 1.335
1.655TyrGlu: 1.655 ± 0.449
1.821TyrPhe: 1.821 ± 0.548
3.311TyrGly: 3.311 ± 0.871
1.49TyrHis: 1.49 ± 0.447
3.311TyrIle: 3.311 ± 0.545
1.986TyrLys: 1.986 ± 0.562
4.304TyrLeu: 4.304 ± 1.203
0.662TyrMet: 0.662 ± 0.274
3.476TyrAsn: 3.476 ± 1.164
1.821TyrPro: 1.821 ± 0.377
0.331TyrGln: 0.331 ± 0.4
4.469TyrArg: 4.469 ± 0.663
3.311TyrSer: 3.311 ± 1.209
1.655TyrThr: 1.655 ± 0.279
2.649TyrVal: 2.649 ± 0.663
0.662TyrTrp: 0.662 ± 0.257
3.145TyrTyr: 3.145 ± 2.028
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (6042 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski