Amino acid dipepetide frequency for Bat polyomavirus 6a

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.958AlaAla: 7.958 ± 3.583
0.0AlaCys: 0.0 ± 0.0
2.653AlaAsp: 2.653 ± 2.646
5.968AlaGlu: 5.968 ± 2.21
3.979AlaPhe: 3.979 ± 0.739
2.653AlaGly: 2.653 ± 0.949
1.326AlaHis: 1.326 ± 0.623
4.642AlaIle: 4.642 ± 1.295
4.642AlaLys: 4.642 ± 1.295
8.621AlaLeu: 8.621 ± 3.469
0.663AlaMet: 0.663 ± 0.536
3.316AlaAsn: 3.316 ± 2.404
2.653AlaPro: 2.653 ± 0.961
3.979AlaGln: 3.979 ± 1.624
3.316AlaArg: 3.316 ± 2.404
1.326AlaSer: 1.326 ± 0.623
3.316AlaThr: 3.316 ± 1.77
5.968AlaVal: 5.968 ± 2.517
1.326AlaTrp: 1.326 ± 0.543
1.989AlaTyr: 1.989 ± 1.224
0.0AlaXaa: 0.0 ± 0.0
Cys
0.663CysAla: 0.663 ± 0.449
0.0CysCys: 0.0 ± 0.0
1.326CysAsp: 1.326 ± 0.91
1.989CysGlu: 1.989 ± 1.346
1.326CysPhe: 1.326 ± 1.99
1.326CysGly: 1.326 ± 0.543
1.989CysHis: 1.989 ± 0.939
0.0CysIle: 0.0 ± 0.0
2.653CysLys: 2.653 ± 0.882
3.316CysLeu: 3.316 ± 1.727
0.663CysMet: 0.663 ± 0.449
1.326CysAsn: 1.326 ± 0.543
0.0CysPro: 0.0 ± 0.0
0.663CysGln: 0.663 ± 0.449
0.663CysArg: 0.663 ± 0.449
1.326CysSer: 1.326 ± 0.897
0.0CysThr: 0.0 ± 0.0
1.326CysVal: 1.326 ± 0.91
1.326CysTrp: 1.326 ± 1.99
1.326CysTyr: 1.326 ± 1.178
0.0CysXaa: 0.0 ± 0.0
Asp
1.989AspAla: 1.989 ± 1.266
0.663AspCys: 0.663 ± 0.449
2.653AspAsp: 2.653 ± 0.908
2.653AspGlu: 2.653 ± 1.346
3.979AspPhe: 3.979 ± 2.05
1.989AspGly: 1.989 ± 1.346
3.979AspHis: 3.979 ± 1.333
3.316AspIle: 3.316 ± 1.159
3.316AspLys: 3.316 ± 0.51
5.305AspLeu: 5.305 ± 1.629
2.653AspMet: 2.653 ± 0.949
1.989AspAsn: 1.989 ± 1.632
2.653AspPro: 2.653 ± 0.949
1.326AspGln: 1.326 ± 0.543
1.989AspArg: 1.989 ± 1.346
1.989AspSer: 1.989 ± 0.455
0.663AspThr: 0.663 ± 0.449
1.326AspVal: 1.326 ± 0.543
1.326AspTrp: 1.326 ± 1.085
1.989AspTyr: 1.989 ± 0.881
0.0AspXaa: 0.0 ± 0.0
Glu
7.958GluAla: 7.958 ± 2.883
3.979GluCys: 3.979 ± 2.05
5.305GluAsp: 5.305 ± 2.11
11.273GluGlu: 11.273 ± 3.477
1.989GluPhe: 1.989 ± 1.346
1.326GluGly: 1.326 ± 1.323
0.663GluHis: 0.663 ± 0.634
1.989GluIle: 1.989 ± 1.124
2.653GluLys: 2.653 ± 1.794
7.958GluLeu: 7.958 ± 2.043
0.0GluMet: 0.0 ± 0.0
5.305GluAsn: 5.305 ± 1.149
2.653GluPro: 2.653 ± 1.086
5.305GluGln: 5.305 ± 2.913
1.326GluArg: 1.326 ± 0.897
3.316GluSer: 3.316 ± 1.66
3.979GluThr: 3.979 ± 1.659
7.294GluVal: 7.294 ± 3.252
0.663GluTrp: 0.663 ± 0.449
2.653GluTyr: 2.653 ± 0.882
0.0GluXaa: 0.0 ± 0.0
Phe
2.653PheAla: 2.653 ± 1.246
2.653PheCys: 2.653 ± 1.308
4.642PheAsp: 4.642 ± 0.845
3.316PheGlu: 3.316 ± 1.661
3.316PhePhe: 3.316 ± 0.51
2.653PheGly: 2.653 ± 1.346
1.326PheHis: 1.326 ± 0.543
1.326PheIle: 1.326 ± 0.543
3.316PheLys: 3.316 ± 1.511
7.294PheLeu: 7.294 ± 3.044
0.663PheMet: 0.663 ± 0.449
0.663PheAsn: 0.663 ± 0.449
2.653PhePro: 2.653 ± 1.246
2.653PheGln: 2.653 ± 0.882
0.663PheArg: 0.663 ± 0.449
4.642PheSer: 4.642 ± 2.225
3.316PheThr: 3.316 ± 0.835
2.653PheVal: 2.653 ± 1.308
0.663PheTrp: 0.663 ± 0.634
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.316GlyAla: 3.316 ± 0.867
0.0GlyCys: 0.0 ± 0.0
3.979GlyAsp: 3.979 ± 2.216
1.989GlyGlu: 1.989 ± 0.455
1.326GlyPhe: 1.326 ± 1.323
5.968GlyGly: 5.968 ± 0.82
0.0GlyHis: 0.0 ± 0.0
2.653GlyIle: 2.653 ± 1.308
3.979GlyLys: 3.979 ± 0.839
5.305GlyLeu: 5.305 ± 2.321
0.663GlyMet: 0.663 ± 0.449
3.979GlyAsn: 3.979 ± 1.708
3.979GlyPro: 3.979 ± 0.909
3.316GlyGln: 3.316 ± 0.867
1.326GlyArg: 1.326 ± 1.269
3.316GlySer: 3.316 ± 1.04
3.316GlyThr: 3.316 ± 0.775
5.968GlyVal: 5.968 ± 1.777
0.0GlyTrp: 0.0 ± 0.0
0.663GlyTyr: 0.663 ± 0.661
0.0GlyXaa: 0.0 ± 0.0
His
1.326HisAla: 1.326 ± 0.91
0.663HisCys: 0.663 ± 0.449
0.0HisAsp: 0.0 ± 0.0
1.989HisGlu: 1.989 ± 0.894
1.989HisPhe: 1.989 ± 0.745
0.0HisGly: 0.0 ± 0.0
0.663HisHis: 0.663 ± 0.449
0.663HisIle: 0.663 ± 0.634
1.326HisLys: 1.326 ± 0.897
3.316HisLeu: 3.316 ± 1.458
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.989HisPro: 1.989 ± 1.033
1.326HisGln: 1.326 ± 1.269
2.653HisArg: 2.653 ± 0.882
0.0HisSer: 0.0 ± 0.0
0.663HisThr: 0.663 ± 0.661
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.663HisTyr: 0.663 ± 0.449
0.0HisXaa: 0.0 ± 0.0
Ile
3.979IleAla: 3.979 ± 0.739
1.989IleCys: 1.989 ± 0.745
1.326IleAsp: 1.326 ± 0.623
3.979IleGlu: 3.979 ± 1.663
3.316IlePhe: 3.316 ± 1.661
0.663IleGly: 0.663 ± 0.634
0.0IleHis: 0.0 ± 0.0
2.653IleIle: 2.653 ± 0.882
1.326IleLys: 1.326 ± 0.543
3.316IleLeu: 3.316 ± 0.775
0.663IleMet: 0.663 ± 0.793
1.989IleAsn: 1.989 ± 0.745
0.663IlePro: 0.663 ± 0.449
1.326IleGln: 1.326 ± 0.543
0.663IleArg: 0.663 ± 0.661
1.989IleSer: 1.989 ± 0.745
5.305IleThr: 5.305 ± 1.954
2.653IleVal: 2.653 ± 0.501
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.979LysAla: 3.979 ± 1.263
1.326LysCys: 1.326 ± 0.91
2.653LysAsp: 2.653 ± 0.882
3.979LysGlu: 3.979 ± 2.05
0.0LysPhe: 0.0 ± 0.0
5.305LysGly: 5.305 ± 1.565
0.663LysHis: 0.663 ± 0.449
0.663LysIle: 0.663 ± 0.449
8.621LysLys: 8.621 ± 3.001
7.294LysLeu: 7.294 ± 2.087
1.989LysMet: 1.989 ± 0.745
5.305LysAsn: 5.305 ± 1.565
2.653LysPro: 2.653 ± 1.517
1.326LysGln: 1.326 ± 0.623
2.653LysArg: 2.653 ± 1.086
6.631LysSer: 6.631 ± 1.393
4.642LysThr: 4.642 ± 1.828
1.989LysVal: 1.989 ± 1.346
0.0LysTrp: 0.0 ± 0.0
1.326LysTyr: 1.326 ± 1.323
0.0LysXaa: 0.0 ± 0.0
Leu
7.958LeuAla: 7.958 ± 4.536
2.653LeuCys: 2.653 ± 1.103
4.642LeuAsp: 4.642 ± 3.14
5.305LeuGlu: 5.305 ± 1.135
5.305LeuPhe: 5.305 ± 2.095
3.979LeuGly: 3.979 ± 1.869
1.989LeuHis: 1.989 ± 1.033
4.642LeuIle: 4.642 ± 0.643
3.316LeuLys: 3.316 ± 2.083
10.61LeuLeu: 10.61 ± 2.226
4.642LeuMet: 4.642 ± 1.804
7.958LeuAsn: 7.958 ± 3.218
6.631LeuPro: 6.631 ± 2.222
6.631LeuGln: 6.631 ± 1.261
7.294LeuArg: 7.294 ± 1.561
7.294LeuSer: 7.294 ± 0.727
3.979LeuThr: 3.979 ± 1.659
3.316LeuVal: 3.316 ± 1.159
0.0LeuTrp: 0.0 ± 0.0
5.968LeuTyr: 5.968 ± 1.315
0.0LeuXaa: 0.0 ± 0.0
Met
2.653MetAla: 2.653 ± 0.949
0.663MetCys: 0.663 ± 0.449
1.326MetAsp: 1.326 ± 0.91
2.653MetGlu: 2.653 ± 0.882
0.0MetPhe: 0.0 ± 0.0
1.989MetGly: 1.989 ± 0.455
0.0MetHis: 0.0 ± 0.0
0.663MetIle: 0.663 ± 0.449
0.663MetLys: 0.663 ± 0.661
0.663MetLeu: 0.663 ± 0.634
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.326MetPro: 1.326 ± 0.897
1.989MetGln: 1.989 ± 0.939
1.326MetArg: 1.326 ± 0.91
1.326MetSer: 1.326 ± 1.178
0.0MetThr: 0.0 ± 0.0
1.326MetVal: 1.326 ± 0.897
0.663MetTrp: 0.663 ± 0.661
0.663MetTyr: 0.663 ± 0.449
0.0MetXaa: 0.0 ± 0.0
Asn
1.989AsnAla: 1.989 ± 0.881
0.663AsnCys: 0.663 ± 0.661
1.989AsnAsp: 1.989 ± 1.124
4.642AsnGlu: 4.642 ± 3.727
3.979AsnPhe: 3.979 ± 0.585
1.989AsnGly: 1.989 ± 0.455
1.326AsnHis: 1.326 ± 0.91
1.989AsnIle: 1.989 ± 0.939
3.316AsnLys: 3.316 ± 1.224
7.294AsnLeu: 7.294 ± 2.599
0.663AsnMet: 0.663 ± 0.819
1.989AsnAsn: 1.989 ± 1.346
3.316AsnPro: 3.316 ± 1.902
0.663AsnGln: 0.663 ± 0.449
0.663AsnArg: 0.663 ± 0.634
3.979AsnSer: 3.979 ± 1.624
1.989AsnThr: 1.989 ± 1.124
3.979AsnVal: 3.979 ± 1.263
1.326AsnTrp: 1.326 ± 1.269
1.989AsnTyr: 1.989 ± 1.175
0.0AsnXaa: 0.0 ± 0.0
Pro
2.653ProAla: 2.653 ± 0.949
1.326ProCys: 1.326 ± 1.178
3.979ProAsp: 3.979 ± 0.755
4.642ProGlu: 4.642 ± 2.46
2.653ProPhe: 2.653 ± 0.908
3.979ProGly: 3.979 ± 0.909
0.663ProHis: 0.663 ± 0.634
1.989ProIle: 1.989 ± 1.266
6.631ProLys: 6.631 ± 1.524
3.979ProLeu: 3.979 ± 2.532
1.326ProMet: 1.326 ± 0.91
0.663ProAsn: 0.663 ± 0.634
3.316ProPro: 3.316 ± 1.224
0.663ProGln: 0.663 ± 0.634
3.316ProArg: 3.316 ± 1.929
1.989ProSer: 1.989 ± 0.881
3.979ProThr: 3.979 ± 1.663
3.979ProVal: 3.979 ± 3.069
0.0ProTrp: 0.0 ± 0.0
2.653ProTyr: 2.653 ± 0.501
0.0ProXaa: 0.0 ± 0.0
Gln
2.653GlnAla: 2.653 ± 1.252
1.989GlnCys: 1.989 ± 2.078
1.326GlnAsp: 1.326 ± 0.752
2.653GlnGlu: 2.653 ± 1.252
3.316GlnPhe: 3.316 ± 1.224
3.316GlnGly: 3.316 ± 1.224
0.663GlnHis: 0.663 ± 0.634
1.989GlnIle: 1.989 ± 1.124
1.989GlnLys: 1.989 ± 1.033
2.653GlnLeu: 2.653 ± 1.308
0.663GlnMet: 0.663 ± 0.59
2.653GlnAsn: 2.653 ± 0.501
2.653GlnPro: 2.653 ± 1.517
3.979GlnGln: 3.979 ± 1.333
2.653GlnArg: 2.653 ± 1.782
1.326GlnSer: 1.326 ± 1.269
3.316GlnThr: 3.316 ± 0.775
3.979GlnVal: 3.979 ± 1.794
0.663GlnTrp: 0.663 ± 0.449
2.653GlnTyr: 2.653 ± 0.761
0.0GlnXaa: 0.0 ± 0.0
Arg
2.653ArgAla: 2.653 ± 1.421
0.0ArgCys: 0.0 ± 0.0
2.653ArgAsp: 2.653 ± 1.308
5.305ArgGlu: 5.305 ± 1.995
2.653ArgPhe: 2.653 ± 1.103
1.326ArgGly: 1.326 ± 0.752
1.326ArgHis: 1.326 ± 0.897
1.326ArgIle: 1.326 ± 0.623
5.968ArgLys: 5.968 ± 1.873
1.989ArgLeu: 1.989 ± 0.894
0.663ArgMet: 0.663 ± 0.661
1.326ArgAsn: 1.326 ± 0.543
1.989ArgPro: 1.989 ± 1.175
1.989ArgGln: 1.989 ± 2.078
3.316ArgArg: 3.316 ± 1.04
1.326ArgSer: 1.326 ± 0.897
3.316ArgThr: 3.316 ± 1.159
4.642ArgVal: 4.642 ± 1.099
1.326ArgTrp: 1.326 ± 0.623
3.979ArgTyr: 3.979 ± 1.609
0.0ArgXaa: 0.0 ± 0.0
Ser
4.642SerAla: 4.642 ± 2.154
1.326SerCys: 1.326 ± 0.91
3.316SerAsp: 3.316 ± 0.835
3.979SerGlu: 3.979 ± 0.991
2.653SerPhe: 2.653 ± 1.252
0.663SerGly: 0.663 ± 0.634
1.326SerHis: 1.326 ± 1.269
1.326SerIle: 1.326 ± 0.543
0.663SerLys: 0.663 ± 0.449
7.294SerLeu: 7.294 ± 1.658
1.326SerMet: 1.326 ± 1.323
4.642SerAsn: 4.642 ± 1.44
1.326SerPro: 1.326 ± 0.543
4.642SerGln: 4.642 ± 0.91
3.316SerArg: 3.316 ± 1.66
3.316SerSer: 3.316 ± 1.04
3.979SerThr: 3.979 ± 0.755
5.968SerVal: 5.968 ± 1.811
2.653SerTrp: 2.653 ± 1.786
0.663SerTyr: 0.663 ± 0.661
0.0SerXaa: 0.0 ± 0.0
Thr
5.305ThrAla: 5.305 ± 1.237
0.663ThrCys: 0.663 ± 0.661
0.0ThrAsp: 0.0 ± 0.0
4.642ThrGlu: 4.642 ± 0.845
3.316ThrPhe: 3.316 ± 0.835
5.305ThrGly: 5.305 ± 1.237
0.0ThrHis: 0.0 ± 0.0
1.326ThrIle: 1.326 ± 1.323
2.653ThrLys: 2.653 ± 1.421
8.621ThrLeu: 8.621 ± 0.931
0.0ThrMet: 0.0 ± 0.0
0.663ThrAsn: 0.663 ± 0.661
7.294ThrPro: 7.294 ± 1.649
1.989ThrGln: 1.989 ± 1.124
2.653ThrArg: 2.653 ± 0.761
1.989ThrSer: 1.989 ± 1.473
5.305ThrThr: 5.305 ± 1.149
3.316ThrVal: 3.316 ± 0.775
0.0ThrTrp: 0.0 ± 0.0
1.989ThrTyr: 1.989 ± 0.881
0.0ThrXaa: 0.0 ± 0.0
Val
4.642ValAla: 4.642 ± 1.981
1.326ValCys: 1.326 ± 1.99
2.653ValAsp: 2.653 ± 1.256
2.653ValGlu: 2.653 ± 1.086
1.326ValPhe: 1.326 ± 0.623
5.305ValGly: 5.305 ± 3.231
0.663ValHis: 0.663 ± 0.449
2.653ValIle: 2.653 ± 1.252
3.316ValLys: 3.316 ± 1.511
3.979ValLeu: 3.979 ± 1.624
0.0ValMet: 0.0 ± 0.0
5.305ValAsn: 5.305 ± 1.629
4.642ValPro: 4.642 ± 1.325
1.326ValGln: 1.326 ± 0.623
5.968ValArg: 5.968 ± 1.811
8.621ValSer: 8.621 ± 1.401
3.979ValThr: 3.979 ± 1.435
2.653ValVal: 2.653 ± 1.517
1.326ValTrp: 1.326 ± 1.085
2.653ValTyr: 2.653 ± 0.949
0.0ValXaa: 0.0 ± 0.0
Trp
1.326TrpAla: 1.326 ± 1.269
0.0TrpCys: 0.0 ± 0.0
1.326TrpAsp: 1.326 ± 0.623
3.316TrpGlu: 3.316 ± 1.04
1.989TrpPhe: 1.989 ± 1.033
0.663TrpGly: 0.663 ± 0.995
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.326TrpLys: 1.326 ± 0.897
0.663TrpLeu: 0.663 ± 0.995
1.326TrpMet: 1.326 ± 1.085
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.663TrpGln: 0.663 ± 0.634
0.663TrpArg: 0.663 ± 0.995
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.663TrpVal: 0.663 ± 0.661
0.663TrpTrp: 0.663 ± 0.449
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.326TyrCys: 1.326 ± 1.99
0.0TyrAsp: 0.0 ± 0.0
0.663TyrGlu: 0.663 ± 0.449
2.653TyrPhe: 2.653 ± 1.503
4.642TyrGly: 4.642 ± 0.643
0.663TyrHis: 0.663 ± 0.449
1.989TyrIle: 1.989 ± 0.455
1.326TyrLys: 1.326 ± 0.897
4.642TyrLeu: 4.642 ± 0.556
0.663TyrMet: 0.663 ± 0.449
1.326TyrAsn: 1.326 ± 0.623
1.989TyrPro: 1.989 ± 1.984
1.326TyrGln: 1.326 ± 0.752
2.653TyrArg: 2.653 ± 0.882
3.316TyrSer: 3.316 ± 1.929
1.989TyrThr: 1.989 ± 1.224
1.989TyrVal: 1.989 ± 0.881
0.663TyrTrp: 0.663 ± 0.449
1.326TyrTyr: 1.326 ± 0.752
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1509 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski