Amino acid dipepetide frequency for Sedimentibacter saalensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.878AlaAla: 5.878 ± 0.104	0.799AlaCys: 0.799 ± 0.028	3.522AlaAsp: 3.522 ± 0.063	4.642AlaGlu: 4.642 ± 0.065	2.73AlaPhe: 2.73 ± 0.053	4.831AlaGly: 4.831 ± 0.085	0.923AlaHis: 0.923 ± 0.03	5.452AlaIle: 5.452 ± 0.079	4.466AlaLys: 4.466 ± 0.062	5.969AlaLeu: 5.969 ± 0.09	2.11AlaMet: 2.11 ± 0.053	2.622AlaAsn: 2.622 ± 0.049	1.675AlaPro: 1.675 ± 0.04	1.683AlaGln: 1.683 ± 0.04	2.152AlaArg: 2.152 ± 0.045	3.831AlaSer: 3.831 ± 0.054	2.959AlaThr: 2.959 ± 0.065	5.82AlaVal: 5.82 ± 0.076	0.408AlaTrp: 0.408 ± 0.018	2.201AlaTyr: 2.201 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.733CysAla: 0.733 ± 0.027	0.195CysCys: 0.195 ± 0.013	0.681CysAsp: 0.681 ± 0.025	0.714CysGlu: 0.714 ± 0.025	0.489CysPhe: 0.489 ± 0.021	1.113CysGly: 1.113 ± 0.038	0.237CysHis: 0.237 ± 0.016	1.007CysIle: 1.007 ± 0.032	0.753CysLys: 0.753 ± 0.03	0.907CysLeu: 0.907 ± 0.028	0.331CysMet: 0.331 ± 0.018	0.559CysAsn: 0.559 ± 0.025	0.512CysPro: 0.512 ± 0.027	0.273CysGln: 0.273 ± 0.016	0.442CysArg: 0.442 ± 0.02	0.917CysSer: 0.917 ± 0.03	0.614CysThr: 0.614 ± 0.021	0.762CysVal: 0.762 ± 0.028	0.078CysTrp: 0.078 ± 0.008	0.391CysTyr: 0.391 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.114AspAla: 3.114 ± 0.053	0.64AspCys: 0.64 ± 0.024	3.05AspAsp: 3.05 ± 0.057	4.977AspGlu: 4.977 ± 0.072	2.687AspPhe: 2.687 ± 0.049	3.739AspGly: 3.739 ± 0.068	0.696AspHis: 0.696 ± 0.026	5.543AspIle: 5.543 ± 0.068	4.617AspLys: 4.617 ± 0.068	4.539AspLeu: 4.539 ± 0.065	1.776AspMet: 1.776 ± 0.046	3.035AspAsn: 3.035 ± 0.056	1.522AspPro: 1.522 ± 0.056	0.977AspGln: 0.977 ± 0.031	1.855AspArg: 1.855 ± 0.045	3.129AspSer: 3.129 ± 0.052	2.72AspThr: 2.72 ± 0.054	4.076AspVal: 4.076 ± 0.06	0.44AspTrp: 0.44 ± 0.018	2.803AspTyr: 2.803 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	4.661GluAla: 4.661 ± 0.071	0.65GluCys: 0.65 ± 0.026	4.021GluAsp: 4.021 ± 0.063	6.397GluGlu: 6.397 ± 0.103	2.945GluPhe: 2.945 ± 0.057	4.268GluGly: 4.268 ± 0.068	1.07GluHis: 1.07 ± 0.029	7.242GluIle: 7.242 ± 0.083	7.22GluLys: 7.22 ± 0.087	6.576GluLeu: 6.576 ± 0.087	2.24GluMet: 2.24 ± 0.039	5.35GluAsn: 5.35 ± 0.08	1.657GluPro: 1.657 ± 0.04	2.177GluGln: 2.177 ± 0.045	2.561GluArg: 2.561 ± 0.052	3.701GluSer: 3.701 ± 0.055	3.584GluThr: 3.584 ± 0.056	4.465GluVal: 4.465 ± 0.063	0.489GluTrp: 0.489 ± 0.025	3.049GluTyr: 3.049 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	2.816PheAla: 2.816 ± 0.053	0.518PheCys: 0.518 ± 0.024	2.6PheAsp: 2.6 ± 0.052	3.084PheGlu: 3.084 ± 0.054	1.879PhePhe: 1.879 ± 0.051	3.036PheGly: 3.036 ± 0.062	0.598PheHis: 0.598 ± 0.024	4.059PheIle: 4.059 ± 0.07	3.031PheLys: 3.031 ± 0.056	3.734PheLeu: 3.734 ± 0.065	1.296PheMet: 1.296 ± 0.037	2.497PheAsn: 2.497 ± 0.054	1.303PhePro: 1.303 ± 0.034	0.967PheGln: 0.967 ± 0.034	1.275PheArg: 1.275 ± 0.034	3.201PheSer: 3.201 ± 0.054	2.416PheThr: 2.416 ± 0.054	2.946PheVal: 2.946 ± 0.059	0.307PheTrp: 0.307 ± 0.017	1.743PheTyr: 1.743 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.613GlyAla: 4.613 ± 0.08	1.112GlyCys: 1.112 ± 0.038	3.223GlyAsp: 3.223 ± 0.053	4.11GlyGlu: 4.11 ± 0.068	3.203GlyPhe: 3.203 ± 0.057	4.711GlyGly: 4.711 ± 0.095	1.114GlyHis: 1.114 ± 0.032	6.709GlyIle: 6.709 ± 0.081	5.163GlyLys: 5.163 ± 0.077	5.59GlyLeu: 5.59 ± 0.083	2.227GlyMet: 2.227 ± 0.049	3.431GlyAsn: 3.431 ± 0.061	1.374GlyPro: 1.374 ± 0.039	1.661GlyGln: 1.661 ± 0.044	2.508GlyArg: 2.508 ± 0.049	4.075GlySer: 4.075 ± 0.061	4.14GlyThr: 4.14 ± 0.076	4.502GlyVal: 4.502 ± 0.071	0.547GlyTrp: 0.547 ± 0.023	3.051GlyTyr: 3.051 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	0.816HisAla: 0.816 ± 0.029	0.22HisCys: 0.22 ± 0.014	0.846HisAsp: 0.846 ± 0.029	1.143HisGlu: 1.143 ± 0.03	0.628HisPhe: 0.628 ± 0.024	1.049HisGly: 1.049 ± 0.032	0.31HisHis: 0.31 ± 0.023	1.339HisIle: 1.339 ± 0.042	1.026HisLys: 1.026 ± 0.032	1.196HisLeu: 1.196 ± 0.035	0.564HisMet: 0.564 ± 0.025	0.824HisAsn: 0.824 ± 0.024	0.689HisPro: 0.689 ± 0.028	0.349HisGln: 0.349 ± 0.016	0.484HisArg: 0.484 ± 0.019	0.903HisSer: 0.903 ± 0.029	0.758HisThr: 0.758 ± 0.026	0.939HisVal: 0.939 ± 0.032	0.121HisTrp: 0.121 ± 0.011	0.647HisTyr: 0.647 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.174IleAla: 6.174 ± 0.09	1.059IleCys: 1.059 ± 0.034	5.363IleAsp: 5.363 ± 0.07	6.628IleGlu: 6.628 ± 0.079	3.788IlePhe: 3.788 ± 0.066	5.87IleGly: 5.87 ± 0.08	1.303IleHis: 1.303 ± 0.033	8.499IleIle: 8.499 ± 0.119	7.198IleLys: 7.198 ± 0.095	7.981IleLeu: 7.981 ± 0.101	2.525IleMet: 2.525 ± 0.048	5.63IleAsn: 5.63 ± 0.083	3.301IlePro: 3.301 ± 0.063	2.021IleGln: 2.021 ± 0.041	2.883IleArg: 2.883 ± 0.053	6.46IleSer: 6.46 ± 0.088	4.99IleThr: 4.99 ± 0.077	6.056IleVal: 6.056 ± 0.076	0.491IleTrp: 0.491 ± 0.021	3.263IleTyr: 3.263 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	4.408LysAla: 4.408 ± 0.067	0.753LysCys: 0.753 ± 0.032	4.682LysAsp: 4.682 ± 0.077	6.787LysGlu: 6.787 ± 0.088	2.841LysPhe: 2.841 ± 0.054	4.503LysGly: 4.503 ± 0.07	1.082LysHis: 1.082 ± 0.029	7.657LysIle: 7.657 ± 0.093	6.914LysLys: 6.914 ± 0.089	6.498LysLeu: 6.498 ± 0.072	2.528LysMet: 2.528 ± 0.044	5.72LysAsn: 5.72 ± 0.082	1.888LysPro: 1.888 ± 0.038	2.127LysGln: 2.127 ± 0.04	2.663LysArg: 2.663 ± 0.055	4.926LysSer: 4.926 ± 0.075	4.219LysThr: 4.219 ± 0.056	4.643LysVal: 4.643 ± 0.075	0.545LysTrp: 0.545 ± 0.026	3.571LysTyr: 3.571 ± 0.055	0.0LysXaa: 0.0 ± 0.0
Leu	5.415LeuAla: 5.415 ± 0.08	1.018LeuCys: 1.018 ± 0.033	4.805LeuAsp: 4.805 ± 0.069	5.87LeuGlu: 5.87 ± 0.085	3.822LeuPhe: 3.822 ± 0.076	5.963LeuGly: 5.963 ± 0.079	1.207LeuHis: 1.207 ± 0.035	7.274LeuIle: 7.274 ± 0.085	7.516LeuLys: 7.516 ± 0.084	7.76LeuLeu: 7.76 ± 0.107	2.69LeuMet: 2.69 ± 0.052	5.323LeuAsn: 5.323 ± 0.072	2.959LeuPro: 2.959 ± 0.052	2.135LeuGln: 2.135 ± 0.05	3.049LeuArg: 3.049 ± 0.056	6.618LeuSer: 6.618 ± 0.086	4.628LeuThr: 4.628 ± 0.067	5.411LeuVal: 5.411 ± 0.074	0.593LeuTrp: 0.593 ± 0.023	3.209LeuTyr: 3.209 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.088MetAla: 2.088 ± 0.048	0.347MetCys: 0.347 ± 0.018	1.789MetAsp: 1.789 ± 0.037	2.239MetGlu: 2.239 ± 0.046	1.234MetPhe: 1.234 ± 0.032	2.11MetGly: 2.11 ± 0.051	0.446MetHis: 0.446 ± 0.021	2.482MetIle: 2.482 ± 0.05	2.758MetLys: 2.758 ± 0.05	2.759MetLeu: 2.759 ± 0.059	0.882MetMet: 0.882 ± 0.03	1.939MetAsn: 1.939 ± 0.041	1.067MetPro: 1.067 ± 0.039	0.779MetGln: 0.779 ± 0.026	0.981MetArg: 0.981 ± 0.027	1.969MetSer: 1.969 ± 0.045	1.628MetThr: 1.628 ± 0.035	1.931MetVal: 1.931 ± 0.043	0.184MetTrp: 0.184 ± 0.012	1.027MetTyr: 1.027 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	3.186AsnAla: 3.186 ± 0.056	0.621AsnCys: 0.621 ± 0.025	2.844AsnAsp: 2.844 ± 0.057	4.169AsnGlu: 4.169 ± 0.069	2.46AsnPhe: 2.46 ± 0.047	3.433AsnGly: 3.433 ± 0.055	0.814AsnHis: 0.814 ± 0.032	6.389AsnIle: 6.389 ± 0.085	4.876AsnLys: 4.876 ± 0.079	5.1AsnLeu: 5.1 ± 0.075	1.888AsnMet: 1.888 ± 0.045	3.79AsnAsn: 3.79 ± 0.079	2.239AsnPro: 2.239 ± 0.048	1.483AsnGln: 1.483 ± 0.04	1.751AsnArg: 1.751 ± 0.044	3.555AsnSer: 3.555 ± 0.063	2.891AsnThr: 2.891 ± 0.052	3.871AsnVal: 3.871 ± 0.063	0.416AsnTrp: 0.416 ± 0.021	2.429AsnTyr: 2.429 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	1.999ProAla: 1.999 ± 0.053	0.348ProCys: 0.348 ± 0.019	1.927ProAsp: 1.927 ± 0.042	2.622ProGlu: 2.622 ± 0.062	1.45ProPhe: 1.45 ± 0.036	2.118ProGly: 2.118 ± 0.05	0.534ProHis: 0.534 ± 0.024	2.394ProIle: 2.394 ± 0.046	1.796ProLys: 1.796 ± 0.04	2.672ProLeu: 2.672 ± 0.047	0.828ProMet: 0.828 ± 0.027	1.377ProAsn: 1.377 ± 0.038	0.788ProPro: 0.788 ± 0.027	0.867ProGln: 0.867 ± 0.031	0.859ProArg: 0.859 ± 0.029	1.899ProSer: 1.899 ± 0.043	1.531ProThr: 1.531 ± 0.038	2.655ProVal: 2.655 ± 0.047	0.248ProTrp: 0.248 ± 0.016	1.356ProTyr: 1.356 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	1.596GlnAla: 1.596 ± 0.041	0.288GlnCys: 0.288 ± 0.017	1.253GlnAsp: 1.253 ± 0.028	1.847GlnGlu: 1.847 ± 0.04	1.002GlnPhe: 1.002 ± 0.032	1.571GlnGly: 1.571 ± 0.037	0.387GlnHis: 0.387 ± 0.02	2.16GlnIle: 2.16 ± 0.046	2.0GlnLys: 2.0 ± 0.046	2.233GlnLeu: 2.233 ± 0.043	0.903GlnMet: 0.903 ± 0.031	1.504GlnAsn: 1.504 ± 0.034	0.681GlnPro: 0.681 ± 0.026	0.786GlnGln: 0.786 ± 0.03	0.997GlnArg: 0.997 ± 0.032	1.6GlnSer: 1.6 ± 0.038	1.229GlnThr: 1.229 ± 0.032	1.64GlnVal: 1.64 ± 0.041	0.22GlnTrp: 0.22 ± 0.014	1.085GlnTyr: 1.085 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.066ArgAla: 2.066 ± 0.043	0.397ArgCys: 0.397 ± 0.02	1.792ArgAsp: 1.792 ± 0.043	2.704ArgGlu: 2.704 ± 0.051	1.42ArgPhe: 1.42 ± 0.031	2.024ArgGly: 2.024 ± 0.046	0.544ArgHis: 0.544 ± 0.021	3.095ArgIle: 3.095 ± 0.057	2.939ArgLys: 2.939 ± 0.056	2.974ArgLeu: 2.974 ± 0.052	1.015ArgMet: 1.015 ± 0.03	2.166ArgAsn: 2.166 ± 0.046	0.904ArgPro: 0.904 ± 0.029	1.06ArgGln: 1.06 ± 0.028	1.383ArgArg: 1.383 ± 0.041	1.667ArgSer: 1.667 ± 0.034	1.748ArgThr: 1.748 ± 0.045	2.133ArgVal: 2.133 ± 0.047	0.223ArgTrp: 0.223 ± 0.014	1.38ArgTyr: 1.38 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	3.989SerAla: 3.989 ± 0.069	0.741SerCys: 0.741 ± 0.029	3.495SerAsp: 3.495 ± 0.067	4.264SerGlu: 4.264 ± 0.064	3.104SerPhe: 3.104 ± 0.058	4.707SerGly: 4.707 ± 0.076	1.083SerHis: 1.083 ± 0.028	5.854SerIle: 5.854 ± 0.083	4.667SerLys: 4.667 ± 0.066	5.828SerLeu: 5.828 ± 0.087	2.072SerMet: 2.072 ± 0.044	3.3SerAsn: 3.3 ± 0.059	1.832SerPro: 1.832 ± 0.041	1.667SerGln: 1.667 ± 0.035	2.224SerArg: 2.224 ± 0.05	4.538SerSer: 4.538 ± 0.075	3.182SerThr: 3.182 ± 0.052	4.333SerVal: 4.333 ± 0.058	0.476SerTrp: 0.476 ± 0.023	2.719SerTyr: 2.719 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	3.827ThrAla: 3.827 ± 0.072	0.53ThrCys: 0.53 ± 0.021	3.056ThrAsp: 3.056 ± 0.045	3.609ThrGlu: 3.609 ± 0.066	2.202ThrPhe: 2.202 ± 0.053	4.449ThrGly: 4.449 ± 0.071	0.799ThrHis: 0.799 ± 0.026	4.592ThrIle: 4.592 ± 0.069	3.293ThrLys: 3.293 ± 0.052	4.455ThrLeu: 4.455 ± 0.065	1.35ThrMet: 1.35 ± 0.03	2.58ThrAsn: 2.58 ± 0.049	1.864ThrPro: 1.864 ± 0.042	1.154ThrGln: 1.154 ± 0.032	1.614ThrArg: 1.614 ± 0.042	3.221ThrSer: 3.221 ± 0.064	2.721ThrThr: 2.721 ± 0.055	4.386ThrVal: 4.386 ± 0.069	0.368ThrTrp: 0.368 ± 0.018	2.035ThrTyr: 2.035 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	4.404ValAla: 4.404 ± 0.078	0.894ValCys: 0.894 ± 0.027	3.865ValAsp: 3.865 ± 0.066	4.952ValGlu: 4.952 ± 0.081	3.127ValPhe: 3.127 ± 0.053	4.26ValGly: 4.26 ± 0.068	0.999ValHis: 0.999 ± 0.03	5.872ValIle: 5.872 ± 0.075	5.149ValLys: 5.149 ± 0.076	6.562ValLeu: 6.562 ± 0.074	2.032ValMet: 2.032 ± 0.045	3.511ValAsn: 3.511 ± 0.062	2.465ValPro: 2.465 ± 0.051	1.69ValGln: 1.69 ± 0.045	2.286ValArg: 2.286 ± 0.044	4.654ValSer: 4.654 ± 0.067	3.73ValThr: 3.73 ± 0.076	5.168ValVal: 5.168 ± 0.077	0.464ValTrp: 0.464 ± 0.02	2.626ValTyr: 2.626 ± 0.05	0.0ValXaa: 0.0 ± 0.0
Trp	0.468TrpAla: 0.468 ± 0.021	0.082TrpCys: 0.082 ± 0.009	0.423TrpAsp: 0.423 ± 0.019	0.456TrpGlu: 0.456 ± 0.021	0.327TrpPhe: 0.327 ± 0.016	0.533TrpGly: 0.533 ± 0.024	0.112TrpHis: 0.112 ± 0.011	0.599TrpIle: 0.599 ± 0.023	0.502TrpLys: 0.502 ± 0.022	0.608TrpLeu: 0.608 ± 0.026	0.22TrpMet: 0.22 ± 0.016	0.456TrpAsn: 0.456 ± 0.021	0.215TrpPro: 0.215 ± 0.014	0.194TrpGln: 0.194 ± 0.015	0.256TrpArg: 0.256 ± 0.014	0.41TrpSer: 0.41 ± 0.021	0.349TrpThr: 0.349 ± 0.019	0.414TrpVal: 0.414 ± 0.02	0.088TrpTrp: 0.088 ± 0.011	0.288TrpTyr: 0.288 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.422TyrAla: 2.422 ± 0.049	0.497TyrCys: 0.497 ± 0.021	2.697TyrAsp: 2.697 ± 0.055	3.107TyrGlu: 3.107 ± 0.06	1.972TyrPhe: 1.972 ± 0.042	2.775TyrGly: 2.775 ± 0.053	0.596TyrHis: 0.596 ± 0.02	3.265TyrIle: 3.265 ± 0.057	3.07TyrLys: 3.07 ± 0.055	3.323TyrLeu: 3.323 ± 0.061	1.161TyrMet: 1.161 ± 0.029	2.588TyrAsn: 2.588 ± 0.055	1.334TyrPro: 1.334 ± 0.035	0.932TyrGln: 0.932 ± 0.029	1.409TyrArg: 1.409 ± 0.04	2.803TyrSer: 2.803 ± 0.054	2.068TyrThr: 2.068 ± 0.049	2.56TyrVal: 2.56 ± 0.055	0.293TyrTrp: 0.293 ± 0.017	1.945TyrTyr: 1.945 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3564 proteins (1119672 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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