Amino acid dipepetide frequency for Human adenovirus D serotype 17 (HAdV-17) (Human adenovirus 17)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.053AlaAla: 7.053 ± 1.733
0.756AlaCys: 0.756 ± 0.57
3.275AlaAsp: 3.275 ± 0.66
5.29AlaGlu: 5.29 ± 0.921
3.275AlaPhe: 3.275 ± 0.828
4.534AlaGly: 4.534 ± 1.435
1.763AlaHis: 1.763 ± 0.848
3.526AlaIle: 3.526 ± 1.331
1.511AlaLys: 1.511 ± 0.837
9.824AlaLeu: 9.824 ± 2.365
1.511AlaMet: 1.511 ± 0.489
3.526AlaAsn: 3.526 ± 1.074
6.045AlaPro: 6.045 ± 1.136
4.03AlaGln: 4.03 ± 0.57
6.297AlaArg: 6.297 ± 1.019
5.542AlaSer: 5.542 ± 0.688
5.542AlaThr: 5.542 ± 1.098
5.29AlaVal: 5.29 ± 0.923
1.008AlaTrp: 1.008 ± 0.358
3.023AlaTyr: 3.023 ± 1.472
0.0AlaXaa: 0.0 ± 0.0
Cys
0.756CysAla: 0.756 ± 0.424
0.504CysCys: 0.504 ± 0.311
0.756CysAsp: 0.756 ± 0.481
0.504CysGlu: 0.504 ± 0.375
0.0CysPhe: 0.0 ± 0.0
2.267CysGly: 2.267 ± 0.789
0.0CysHis: 0.0 ± 0.0
0.252CysIle: 0.252 ± 0.256
0.0CysLys: 0.0 ± 0.0
0.756CysLeu: 0.756 ± 0.306
0.252CysMet: 0.252 ± 0.289
0.252CysAsn: 0.252 ± 0.256
1.259CysPro: 1.259 ± 0.752
0.252CysGln: 0.252 ± 0.256
0.756CysArg: 0.756 ± 0.415
0.504CysSer: 0.504 ± 0.375
0.252CysThr: 0.252 ± 0.256
0.756CysVal: 0.756 ± 0.562
0.504CysTrp: 0.504 ± 0.375
1.008CysTyr: 1.008 ± 0.505
0.0CysXaa: 0.0 ± 0.0
Asp
3.778AspAla: 3.778 ± 1.1
0.504AspCys: 0.504 ± 0.367
3.778AspAsp: 3.778 ± 0.75
4.534AspGlu: 4.534 ± 1.091
2.519AspPhe: 2.519 ± 0.7
1.763AspGly: 1.763 ± 0.957
1.008AspHis: 1.008 ± 0.533
2.519AspIle: 2.519 ± 0.824
2.015AspLys: 2.015 ± 0.767
6.801AspLeu: 6.801 ± 1.519
1.511AspMet: 1.511 ± 0.424
2.519AspAsn: 2.519 ± 0.69
4.282AspPro: 4.282 ± 0.657
0.504AspGln: 0.504 ± 0.318
4.534AspArg: 4.534 ± 1.535
5.793AspSer: 5.793 ± 0.798
2.771AspThr: 2.771 ± 0.711
3.778AspVal: 3.778 ± 0.785
0.504AspTrp: 0.504 ± 0.292
2.267AspTyr: 2.267 ± 0.882
0.0AspXaa: 0.0 ± 0.0
Glu
5.793GluAla: 5.793 ± 1.285
0.504GluCys: 0.504 ± 0.375
4.282GluAsp: 4.282 ± 0.774
8.564GluGlu: 8.564 ± 3.057
1.763GluPhe: 1.763 ± 0.698
3.778GluGly: 3.778 ± 1.357
1.511GluHis: 1.511 ± 0.675
3.023GluIle: 3.023 ± 1.01
2.771GluLys: 2.771 ± 0.744
6.045GluLeu: 6.045 ± 1.333
1.763GluMet: 1.763 ± 0.788
1.763GluAsn: 1.763 ± 0.939
2.771GluPro: 2.771 ± 0.758
2.267GluGln: 2.267 ± 0.496
6.297GluArg: 6.297 ± 1.95
3.023GluSer: 3.023 ± 0.882
2.771GluThr: 2.771 ± 0.856
3.778GluVal: 3.778 ± 0.536
1.259GluTrp: 1.259 ± 0.752
3.023GluTyr: 3.023 ± 0.929
0.0GluXaa: 0.0 ± 0.0
Phe
2.015PheAla: 2.015 ± 0.841
0.504PheCys: 0.504 ± 0.311
2.771PheAsp: 2.771 ± 0.588
2.015PheGlu: 2.015 ± 0.802
1.008PhePhe: 1.008 ± 0.448
1.259PheGly: 1.259 ± 0.697
0.504PheHis: 0.504 ± 0.291
0.756PheIle: 0.756 ± 0.423
2.015PheLys: 2.015 ± 0.611
4.786PheLeu: 4.786 ± 0.915
2.519PheMet: 2.519 ± 0.49
2.267PheAsn: 2.267 ± 0.577
2.015PhePro: 2.015 ± 0.352
2.015PheGln: 2.015 ± 0.406
3.778PheArg: 3.778 ± 0.721
2.771PheSer: 2.771 ± 0.61
2.771PheThr: 2.771 ± 0.923
3.023PheVal: 3.023 ± 0.787
0.252PheTrp: 0.252 ± 0.289
2.519PheTyr: 2.519 ± 0.763
0.0PheXaa: 0.0 ± 0.0
Gly
4.03GlyAla: 4.03 ± 1.286
1.008GlyCys: 1.008 ± 0.444
3.526GlyAsp: 3.526 ± 1.294
3.023GlyGlu: 3.023 ± 1.002
2.015GlyPhe: 2.015 ± 0.696
4.282GlyGly: 4.282 ± 0.83
1.511GlyHis: 1.511 ± 0.617
2.771GlyIle: 2.771 ± 0.685
2.267GlyLys: 2.267 ± 0.901
6.045GlyLeu: 6.045 ± 1.999
1.008GlyMet: 1.008 ± 0.36
1.259GlyAsn: 1.259 ± 0.667
3.275GlyPro: 3.275 ± 0.708
1.763GlyGln: 1.763 ± 0.593
4.534GlyArg: 4.534 ± 0.729
3.778GlySer: 3.778 ± 1.291
2.015GlyThr: 2.015 ± 0.953
5.038GlyVal: 5.038 ± 1.833
0.756GlyTrp: 0.756 ± 0.359
1.511GlyTyr: 1.511 ± 0.729
0.0GlyXaa: 0.0 ± 0.0
His
2.519HisAla: 2.519 ± 0.799
0.252HisCys: 0.252 ± 0.187
0.504HisAsp: 0.504 ± 0.292
1.008HisGlu: 1.008 ± 0.544
1.008HisPhe: 1.008 ± 0.532
1.259HisGly: 1.259 ± 0.428
0.252HisHis: 0.252 ± 0.187
0.756HisIle: 0.756 ± 0.375
0.252HisLys: 0.252 ± 0.309
1.511HisLeu: 1.511 ± 0.707
0.0HisMet: 0.0 ± 0.0
0.504HisAsn: 0.504 ± 0.375
1.763HisPro: 1.763 ± 0.69
0.504HisGln: 0.504 ± 0.375
2.771HisArg: 2.771 ± 1.062
1.511HisSer: 1.511 ± 0.504
0.756HisThr: 0.756 ± 0.418
1.511HisVal: 1.511 ± 0.525
1.008HisTrp: 1.008 ± 0.714
0.252HisTyr: 0.252 ± 0.256
0.0HisXaa: 0.0 ± 0.0
Ile
3.526IleAla: 3.526 ± 0.702
0.252IleCys: 0.252 ± 0.187
2.015IleAsp: 2.015 ± 0.656
2.267IleGlu: 2.267 ± 0.951
1.008IlePhe: 1.008 ± 0.749
2.267IleGly: 2.267 ± 0.665
0.252IleHis: 0.252 ± 0.309
0.756IleIle: 0.756 ± 0.281
2.015IleLys: 2.015 ± 0.783
3.778IleLeu: 3.778 ± 1.011
0.756IleMet: 0.756 ± 0.352
2.771IleAsn: 2.771 ± 0.862
0.756IlePro: 0.756 ± 0.362
0.756IleGln: 0.756 ± 0.481
3.023IleArg: 3.023 ± 1.056
2.015IleSer: 2.015 ± 0.73
1.763IleThr: 1.763 ± 0.412
3.778IleVal: 3.778 ± 0.72
0.504IleTrp: 0.504 ± 0.26
1.008IleTyr: 1.008 ± 0.458
0.0IleXaa: 0.0 ± 0.0
Lys
3.023LysAla: 3.023 ± 1.147
0.504LysCys: 0.504 ± 0.24
2.015LysAsp: 2.015 ± 0.515
1.259LysGlu: 1.259 ± 0.53
1.259LysPhe: 1.259 ± 0.515
2.519LysGly: 2.519 ± 1.148
0.756LysHis: 0.756 ± 0.418
2.015LysIle: 2.015 ± 0.744
3.023LysLys: 3.023 ± 1.201
5.542LysLeu: 5.542 ± 1.336
0.504LysMet: 0.504 ± 0.311
2.519LysAsn: 2.519 ± 0.666
1.008LysPro: 1.008 ± 0.488
1.511LysGln: 1.511 ± 0.655
2.015LysArg: 2.015 ± 0.663
2.267LysSer: 2.267 ± 0.622
0.756LysThr: 0.756 ± 0.346
2.519LysVal: 2.519 ± 0.929
0.0LysTrp: 0.0 ± 0.0
1.511LysTyr: 1.511 ± 0.675
0.0LysXaa: 0.0 ± 0.0
Leu
9.068LeuAla: 9.068 ± 1.254
1.008LeuCys: 1.008 ± 0.579
4.786LeuAsp: 4.786 ± 0.736
5.793LeuGlu: 5.793 ± 1.515
2.519LeuPhe: 2.519 ± 0.652
5.038LeuGly: 5.038 ± 1.534
2.267LeuHis: 2.267 ± 0.638
2.267LeuIle: 2.267 ± 0.881
5.038LeuLys: 5.038 ± 1.547
7.305LeuLeu: 7.305 ± 1.57
3.778LeuMet: 3.778 ± 0.808
3.526LeuAsn: 3.526 ± 0.818
6.549LeuPro: 6.549 ± 1.548
5.29LeuGln: 5.29 ± 0.809
8.564LeuArg: 8.564 ± 1.414
5.793LeuSer: 5.793 ± 1.084
7.053LeuThr: 7.053 ± 1.233
8.312LeuVal: 8.312 ± 1.198
1.763LeuTrp: 1.763 ± 0.535
3.023LeuTyr: 3.023 ± 0.933
0.0LeuXaa: 0.0 ± 0.0
Met
2.771MetAla: 2.771 ± 0.544
0.252MetCys: 0.252 ± 0.187
2.267MetAsp: 2.267 ± 0.372
2.015MetGlu: 2.015 ± 0.626
1.008MetPhe: 1.008 ± 0.667
1.008MetGly: 1.008 ± 0.364
0.756MetHis: 0.756 ± 0.629
0.252MetIle: 0.252 ± 0.256
0.756MetLys: 0.756 ± 0.433
1.511MetLeu: 1.511 ± 0.57
0.0MetMet: 0.0 ± 0.0
0.756MetAsn: 0.756 ± 0.431
2.771MetPro: 2.771 ± 0.721
1.511MetGln: 1.511 ± 0.64
1.763MetArg: 1.763 ± 0.845
1.259MetSer: 1.259 ± 0.523
1.259MetThr: 1.259 ± 0.299
1.008MetVal: 1.008 ± 0.399
0.0MetTrp: 0.0 ± 0.0
1.008MetTyr: 1.008 ± 0.298
0.0MetXaa: 0.0 ± 0.0
Asn
2.771AsnAla: 2.771 ± 0.992
0.756AsnCys: 0.756 ± 0.321
3.275AsnAsp: 3.275 ± 0.72
2.267AsnGlu: 2.267 ± 0.481
3.778AsnPhe: 3.778 ± 1.067
2.771AsnGly: 2.771 ± 0.784
0.756AsnHis: 0.756 ± 0.429
2.771AsnIle: 2.771 ± 0.756
2.267AsnLys: 2.267 ± 1.039
4.03AsnLeu: 4.03 ± 1.025
0.504AsnMet: 0.504 ± 0.306
1.511AsnAsn: 1.511 ± 0.424
3.526AsnPro: 3.526 ± 1.12
1.259AsnGln: 1.259 ± 0.48
3.023AsnArg: 3.023 ± 0.973
3.526AsnSer: 3.526 ± 0.93
0.756AsnThr: 0.756 ± 0.449
1.259AsnVal: 1.259 ± 0.615
1.008AsnTrp: 1.008 ± 0.502
2.015AsnTyr: 2.015 ± 0.898
0.0AsnXaa: 0.0 ± 0.0
Pro
6.297ProAla: 6.297 ± 1.469
0.252ProCys: 0.252 ± 0.256
4.282ProAsp: 4.282 ± 1.296
4.282ProGlu: 4.282 ± 1.171
4.03ProPhe: 4.03 ± 0.905
4.03ProGly: 4.03 ± 0.867
1.511ProHis: 1.511 ± 0.553
2.015ProIle: 2.015 ± 0.536
2.267ProLys: 2.267 ± 0.884
5.038ProLeu: 5.038 ± 1.562
0.756ProMet: 0.756 ± 0.413
2.519ProAsn: 2.519 ± 0.467
9.572ProPro: 9.572 ± 2.718
2.519ProGln: 2.519 ± 0.528
5.038ProArg: 5.038 ± 0.841
3.275ProSer: 3.275 ± 1.024
4.282ProThr: 4.282 ± 1.467
3.778ProVal: 3.778 ± 0.691
0.504ProTrp: 0.504 ± 0.375
1.763ProTyr: 1.763 ± 0.464
0.0ProXaa: 0.0 ± 0.0
Gln
3.526GlnAla: 3.526 ± 0.93
0.504GlnCys: 0.504 ± 0.375
2.267GlnAsp: 2.267 ± 0.739
3.023GlnGlu: 3.023 ± 0.599
1.259GlnPhe: 1.259 ± 0.617
1.511GlnGly: 1.511 ± 0.368
1.008GlnHis: 1.008 ± 0.398
1.259GlnIle: 1.259 ± 0.366
1.259GlnLys: 1.259 ± 0.796
3.275GlnLeu: 3.275 ± 0.644
1.259GlnMet: 1.259 ± 0.465
2.519GlnAsn: 2.519 ± 1.087
5.038GlnPro: 5.038 ± 0.848
2.771GlnGln: 2.771 ± 0.679
3.526GlnArg: 3.526 ± 0.654
2.771GlnSer: 2.771 ± 1.285
2.771GlnThr: 2.771 ± 0.85
2.015GlnVal: 2.015 ± 0.737
0.0GlnTrp: 0.0 ± 0.0
0.756GlnTyr: 0.756 ± 0.398
0.0GlnXaa: 0.0 ± 0.0
Arg
8.564ArgAla: 8.564 ± 1.801
1.511ArgCys: 1.511 ± 0.453
4.282ArgAsp: 4.282 ± 1.319
6.801ArgGlu: 6.801 ± 1.463
3.275ArgPhe: 3.275 ± 0.968
4.534ArgGly: 4.534 ± 1.137
1.763ArgHis: 1.763 ± 0.715
3.023ArgIle: 3.023 ± 0.356
1.259ArgLys: 1.259 ± 0.515
6.801ArgLeu: 6.801 ± 1.582
1.008ArgMet: 1.008 ± 0.313
3.778ArgAsn: 3.778 ± 0.776
5.038ArgPro: 5.038 ± 1.21
3.526ArgGln: 3.526 ± 1.17
7.809ArgArg: 7.809 ± 2.298
4.282ArgSer: 4.282 ± 1.37
4.03ArgThr: 4.03 ± 0.803
4.786ArgVal: 4.786 ± 1.214
1.763ArgTrp: 1.763 ± 0.376
1.763ArgTyr: 1.763 ± 0.625
0.0ArgXaa: 0.0 ± 0.0
Ser
5.29SerAla: 5.29 ± 1.369
0.0SerCys: 0.0 ± 0.0
3.275SerAsp: 3.275 ± 0.518
3.526SerGlu: 3.526 ± 0.732
3.275SerPhe: 3.275 ± 0.6
3.526SerGly: 3.526 ± 1.055
1.763SerHis: 1.763 ± 1.102
2.267SerIle: 2.267 ± 0.581
2.519SerLys: 2.519 ± 0.814
7.809SerLeu: 7.809 ± 1.324
0.756SerMet: 0.756 ± 0.487
2.771SerAsn: 2.771 ± 0.843
2.771SerPro: 2.771 ± 0.99
2.267SerGln: 2.267 ± 0.504
6.549SerArg: 6.549 ± 1.014
5.29SerSer: 5.29 ± 1.384
2.771SerThr: 2.771 ± 0.96
4.786SerVal: 4.786 ± 0.852
0.504SerTrp: 0.504 ± 0.509
2.519SerTyr: 2.519 ± 0.852
0.0SerXaa: 0.0 ± 0.0
Thr
2.771ThrAla: 2.771 ± 1.254
1.259ThrCys: 1.259 ± 0.684
2.519ThrAsp: 2.519 ± 0.801
2.519ThrGlu: 2.519 ± 0.396
3.023ThrPhe: 3.023 ± 0.865
2.771ThrGly: 2.771 ± 1.139
1.008ThrHis: 1.008 ± 0.399
2.771ThrIle: 2.771 ± 1.071
1.008ThrLys: 1.008 ± 0.49
7.557ThrLeu: 7.557 ± 1.012
1.511ThrMet: 1.511 ± 0.541
2.771ThrAsn: 2.771 ± 0.998
3.778ThrPro: 3.778 ± 0.505
1.763ThrGln: 1.763 ± 0.787
3.023ThrArg: 3.023 ± 0.661
2.771ThrSer: 2.771 ± 0.491
3.778ThrThr: 3.778 ± 0.923
4.282ThrVal: 4.282 ± 0.403
1.259ThrTrp: 1.259 ± 0.514
2.519ThrTyr: 2.519 ± 0.558
0.0ThrXaa: 0.0 ± 0.0
Val
5.038ValAla: 5.038 ± 0.83
0.504ValCys: 0.504 ± 0.375
5.038ValAsp: 5.038 ± 0.79
3.526ValGlu: 3.526 ± 0.888
3.023ValPhe: 3.023 ± 1.119
3.526ValGly: 3.526 ± 0.674
0.756ValHis: 0.756 ± 0.573
0.756ValIle: 0.756 ± 0.29
1.511ValLys: 1.511 ± 0.833
5.038ValLeu: 5.038 ± 1.07
2.267ValMet: 2.267 ± 0.83
3.275ValAsn: 3.275 ± 0.983
4.03ValPro: 4.03 ± 0.809
5.038ValGln: 5.038 ± 0.897
4.03ValArg: 4.03 ± 0.712
4.786ValSer: 4.786 ± 1.505
5.038ValThr: 5.038 ± 1.188
5.29ValVal: 5.29 ± 1.993
1.008ValTrp: 1.008 ± 0.448
3.778ValTyr: 3.778 ± 1.01
0.0ValXaa: 0.0 ± 0.0
Trp
0.756TrpAla: 0.756 ± 0.424
0.0TrpCys: 0.0 ± 0.0
1.259TrpAsp: 1.259 ± 0.426
1.008TrpGlu: 1.008 ± 0.544
0.252TrpPhe: 0.252 ± 0.254
1.008TrpGly: 1.008 ± 0.298
0.0TrpHis: 0.0 ± 0.0
0.504TrpIle: 0.504 ± 0.26
1.008TrpLys: 1.008 ± 0.544
1.511TrpLeu: 1.511 ± 0.384
0.504TrpMet: 0.504 ± 0.26
2.015TrpAsn: 2.015 ± 1.117
0.504TrpPro: 0.504 ± 0.337
1.008TrpGln: 1.008 ± 0.495
0.252TrpArg: 0.252 ± 0.187
1.259TrpSer: 1.259 ± 0.53
1.259TrpThr: 1.259 ± 0.485
0.0TrpVal: 0.0 ± 0.0
0.252TrpTrp: 0.252 ± 0.187
0.252TrpTyr: 0.252 ± 0.254
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.275TyrAla: 3.275 ± 0.77
0.756TyrCys: 0.756 ± 0.562
1.511TyrAsp: 1.511 ± 0.431
3.526TyrGlu: 3.526 ± 1.115
2.267TyrPhe: 2.267 ± 0.625
1.763TyrGly: 1.763 ± 0.592
0.756TyrHis: 0.756 ± 0.481
1.008TyrIle: 1.008 ± 0.531
1.763TyrLys: 1.763 ± 0.403
3.778TyrLeu: 3.778 ± 0.971
1.511TyrMet: 1.511 ± 0.685
1.008TyrAsn: 1.008 ± 0.613
1.259TyrPro: 1.259 ± 0.467
1.763TyrGln: 1.763 ± 0.622
2.015TyrArg: 2.015 ± 0.478
2.015TyrSer: 2.015 ± 0.555
2.267TyrThr: 2.267 ± 0.773
2.267TyrVal: 2.267 ± 0.457
0.756TyrTrp: 0.756 ± 0.29
0.252TyrTyr: 0.252 ± 0.256
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (3971 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski