Amino acid dipepetide frequency for Rhesus adenovirus 65

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.424AlaAla: 8.424 ± 1.918
0.702AlaCys: 0.702 ± 0.362
3.276AlaAsp: 3.276 ± 0.657
3.861AlaGlu: 3.861 ± 0.855
3.042AlaPhe: 3.042 ± 0.595
5.031AlaGly: 5.031 ± 0.68
1.287AlaHis: 1.287 ± 0.358
3.393AlaIle: 3.393 ± 0.657
1.989AlaLys: 1.989 ± 0.47
7.956AlaLeu: 7.956 ± 1.226
1.404AlaMet: 1.404 ± 0.457
3.744AlaAsn: 3.744 ± 0.609
5.499AlaPro: 5.499 ± 0.614
3.276AlaGln: 3.276 ± 0.468
5.031AlaArg: 5.031 ± 1.151
5.031AlaSer: 5.031 ± 0.752
3.51AlaThr: 3.51 ± 0.761
6.669AlaVal: 6.669 ± 0.92
0.936AlaTrp: 0.936 ± 0.258
2.925AlaTyr: 2.925 ± 0.487
0.0AlaXaa: 0.0 ± 0.0
Cys
1.638CysAla: 1.638 ± 0.503
0.936CysCys: 0.936 ± 0.322
0.819CysAsp: 0.819 ± 0.284
0.819CysGlu: 0.819 ± 0.296
0.468CysPhe: 0.468 ± 0.255
1.638CysGly: 1.638 ± 0.461
0.468CysHis: 0.468 ± 0.217
0.702CysIle: 0.702 ± 0.392
0.234CysLys: 0.234 ± 0.22
1.287CysLeu: 1.287 ± 0.407
0.234CysMet: 0.234 ± 0.175
0.468CysAsn: 0.468 ± 0.2
0.468CysPro: 0.468 ± 0.202
0.351CysGln: 0.351 ± 0.169
0.702CysArg: 0.702 ± 0.405
0.819CysSer: 0.819 ± 0.315
0.702CysThr: 0.702 ± 0.258
0.819CysVal: 0.819 ± 0.327
0.351CysTrp: 0.351 ± 0.211
1.404CysTyr: 1.404 ± 0.413
0.0CysXaa: 0.0 ± 0.0
Asp
2.925AspAla: 2.925 ± 0.658
0.702AspCys: 0.702 ± 0.294
1.638AspAsp: 1.638 ± 0.572
3.042AspGlu: 3.042 ± 0.54
2.106AspPhe: 2.106 ± 0.53
2.925AspGly: 2.925 ± 0.545
0.702AspHis: 0.702 ± 0.277
2.223AspIle: 2.223 ± 0.568
1.404AspLys: 1.404 ± 0.28
5.616AspLeu: 5.616 ± 1.032
1.287AspMet: 1.287 ± 0.355
2.457AspAsn: 2.457 ± 0.591
3.51AspPro: 3.51 ± 0.552
0.819AspGln: 0.819 ± 0.247
3.744AspArg: 3.744 ± 0.861
4.914AspSer: 4.914 ± 0.855
2.808AspThr: 2.808 ± 0.758
3.627AspVal: 3.627 ± 0.724
0.585AspTrp: 0.585 ± 0.185
1.755AspTyr: 1.755 ± 0.441
0.0AspXaa: 0.0 ± 0.0
Glu
3.861GluAla: 3.861 ± 0.897
0.702GluCys: 0.702 ± 0.321
3.861GluAsp: 3.861 ± 0.665
4.797GluGlu: 4.797 ± 1.208
2.34GluPhe: 2.34 ± 0.433
3.276GluGly: 3.276 ± 0.888
1.404GluHis: 1.404 ± 0.494
2.34GluIle: 2.34 ± 0.402
2.691GluLys: 2.691 ± 0.727
4.797GluLeu: 4.797 ± 0.781
1.638GluMet: 1.638 ± 0.473
3.276GluAsn: 3.276 ± 0.624
3.393GluPro: 3.393 ± 0.569
2.34GluGln: 2.34 ± 0.367
3.393GluArg: 3.393 ± 0.83
2.808GluSer: 2.808 ± 0.567
3.042GluThr: 3.042 ± 0.725
3.744GluVal: 3.744 ± 0.741
0.936GluTrp: 0.936 ± 0.288
1.287GluTyr: 1.287 ± 0.365
0.0GluXaa: 0.0 ± 0.0
Phe
2.457PheAla: 2.457 ± 0.404
0.702PheCys: 0.702 ± 0.286
3.159PheAsp: 3.159 ± 0.686
1.755PheGlu: 1.755 ± 0.52
1.638PhePhe: 1.638 ± 0.466
1.053PheGly: 1.053 ± 0.378
1.287PheHis: 1.287 ± 0.389
1.755PheIle: 1.755 ± 0.431
1.638PheLys: 1.638 ± 0.424
3.042PheLeu: 3.042 ± 0.639
1.287PheMet: 1.287 ± 0.302
3.042PheAsn: 3.042 ± 0.543
2.106PhePro: 2.106 ± 0.391
2.574PheGln: 2.574 ± 0.436
2.691PheArg: 2.691 ± 0.566
2.574PheSer: 2.574 ± 0.459
3.042PheThr: 3.042 ± 0.467
3.159PheVal: 3.159 ± 0.547
0.468PheTrp: 0.468 ± 0.207
1.404PheTyr: 1.404 ± 0.344
0.0PheXaa: 0.0 ± 0.0
Gly
6.201GlyAla: 6.201 ± 0.865
1.17GlyCys: 1.17 ± 0.37
2.574GlyAsp: 2.574 ± 0.456
2.808GlyGlu: 2.808 ± 0.455
2.223GlyPhe: 2.223 ± 0.433
4.095GlyGly: 4.095 ± 0.557
1.872GlyHis: 1.872 ± 0.481
1.989GlyIle: 1.989 ± 0.472
1.521GlyLys: 1.521 ± 0.553
6.318GlyLeu: 6.318 ± 1.324
1.287GlyMet: 1.287 ± 0.253
3.042GlyAsn: 3.042 ± 0.816
3.042GlyPro: 3.042 ± 0.596
2.691GlyGln: 2.691 ± 0.679
4.563GlyArg: 4.563 ± 0.795
6.084GlySer: 6.084 ± 0.77
3.276GlyThr: 3.276 ± 0.591
5.967GlyVal: 5.967 ± 0.907
0.819GlyTrp: 0.819 ± 0.254
1.989GlyTyr: 1.989 ± 0.487
0.0GlyXaa: 0.0 ± 0.0
His
1.872HisAla: 1.872 ± 0.431
0.585HisCys: 0.585 ± 0.268
0.468HisAsp: 0.468 ± 0.299
0.468HisGlu: 0.468 ± 0.177
0.702HisPhe: 0.702 ± 0.317
1.872HisGly: 1.872 ± 0.586
0.468HisHis: 0.468 ± 0.226
0.936HisIle: 0.936 ± 0.31
0.585HisLys: 0.585 ± 0.291
1.755HisLeu: 1.755 ± 0.434
0.234HisMet: 0.234 ± 0.161
1.287HisAsn: 1.287 ± 0.365
1.404HisPro: 1.404 ± 0.686
0.936HisGln: 0.936 ± 0.282
2.106HisArg: 2.106 ± 0.376
1.053HisSer: 1.053 ± 0.384
0.936HisThr: 0.936 ± 0.307
1.521HisVal: 1.521 ± 0.523
0.585HisTrp: 0.585 ± 0.346
0.234HisTyr: 0.234 ± 0.135
0.0HisXaa: 0.0 ± 0.0
Ile
3.159IleAla: 3.159 ± 0.593
0.819IleCys: 0.819 ± 0.229
1.404IleAsp: 1.404 ± 0.4
1.872IleGlu: 1.872 ± 0.351
1.287IlePhe: 1.287 ± 0.451
2.223IleGly: 2.223 ± 0.549
0.819IleHis: 0.819 ± 0.292
1.17IleIle: 1.17 ± 0.466
2.106IleLys: 2.106 ± 0.556
3.159IleLeu: 3.159 ± 0.494
1.287IleMet: 1.287 ± 0.224
2.457IleAsn: 2.457 ± 0.514
2.457IlePro: 2.457 ± 0.477
1.755IleGln: 1.755 ± 0.467
2.574IleArg: 2.574 ± 0.561
2.691IleSer: 2.691 ± 0.46
2.223IleThr: 2.223 ± 0.462
2.34IleVal: 2.34 ± 0.417
0.117IleTrp: 0.117 ± 0.114
1.287IleTyr: 1.287 ± 0.496
0.0IleXaa: 0.0 ± 0.0
Lys
1.989LysAla: 1.989 ± 0.543
0.936LysCys: 0.936 ± 0.26
1.638LysAsp: 1.638 ± 0.363
1.872LysGlu: 1.872 ± 0.585
2.106LysPhe: 2.106 ± 0.379
2.34LysGly: 2.34 ± 0.532
0.819LysHis: 0.819 ± 0.286
1.287LysIle: 1.287 ± 0.302
2.808LysLys: 2.808 ± 0.839
2.691LysLeu: 2.691 ± 0.991
1.404LysMet: 1.404 ± 0.609
1.521LysAsn: 1.521 ± 0.343
2.34LysPro: 2.34 ± 0.516
0.702LysGln: 0.702 ± 0.271
3.276LysArg: 3.276 ± 0.946
1.872LysSer: 1.872 ± 0.541
1.638LysThr: 1.638 ± 0.322
2.574LysVal: 2.574 ± 0.559
0.234LysTrp: 0.234 ± 0.139
0.468LysTyr: 0.468 ± 0.204
0.0LysXaa: 0.0 ± 0.0
Leu
7.254LeuAla: 7.254 ± 1.056
1.17LeuCys: 1.17 ± 0.391
4.914LeuAsp: 4.914 ± 0.828
5.148LeuGlu: 5.148 ± 0.979
2.223LeuPhe: 2.223 ± 0.554
6.318LeuGly: 6.318 ± 1.115
2.808LeuHis: 2.808 ± 0.641
2.223LeuIle: 2.223 ± 0.361
4.212LeuLys: 4.212 ± 0.602
9.126LeuLeu: 9.126 ± 1.494
3.042LeuMet: 3.042 ± 0.378
5.265LeuAsn: 5.265 ± 0.827
5.85LeuPro: 5.85 ± 1.066
5.616LeuGln: 5.616 ± 1.32
8.541LeuArg: 8.541 ± 1.265
6.435LeuSer: 6.435 ± 1.014
6.903LeuThr: 6.903 ± 1.257
5.733LeuVal: 5.733 ± 0.995
1.404LeuTrp: 1.404 ± 0.395
3.861LeuTyr: 3.861 ± 0.807
0.0LeuXaa: 0.0 ± 0.0
Met
2.925MetAla: 2.925 ± 0.533
0.234MetCys: 0.234 ± 0.159
1.17MetAsp: 1.17 ± 0.314
2.106MetGlu: 2.106 ± 0.539
0.702MetPhe: 0.702 ± 0.314
1.404MetGly: 1.404 ± 0.354
0.702MetHis: 0.702 ± 0.275
0.819MetIle: 0.819 ± 0.269
0.819MetLys: 0.819 ± 0.325
2.106MetLeu: 2.106 ± 0.673
0.468MetMet: 0.468 ± 0.192
1.638MetAsn: 1.638 ± 0.453
1.755MetPro: 1.755 ± 0.405
1.053MetGln: 1.053 ± 0.305
1.17MetArg: 1.17 ± 0.337
2.106MetSer: 2.106 ± 0.361
1.287MetThr: 1.287 ± 0.326
0.819MetVal: 0.819 ± 0.271
0.468MetTrp: 0.468 ± 0.258
1.287MetTyr: 1.287 ± 0.259
0.0MetXaa: 0.0 ± 0.0
Asn
3.393AsnAla: 3.393 ± 0.692
0.819AsnCys: 0.819 ± 0.284
3.51AsnAsp: 3.51 ± 0.831
1.989AsnGlu: 1.989 ± 0.53
2.574AsnPhe: 2.574 ± 0.669
3.627AsnGly: 3.627 ± 0.841
0.819AsnHis: 0.819 ± 0.365
2.34AsnIle: 2.34 ± 0.52
1.521AsnLys: 1.521 ± 0.364
4.212AsnLeu: 4.212 ± 0.698
1.755AsnMet: 1.755 ± 0.601
3.393AsnAsn: 3.393 ± 1.218
4.68AsnPro: 4.68 ± 0.706
1.638AsnGln: 1.638 ± 0.423
2.925AsnArg: 2.925 ± 0.547
4.563AsnSer: 4.563 ± 0.955
2.106AsnThr: 2.106 ± 0.603
3.276AsnVal: 3.276 ± 0.461
0.702AsnTrp: 0.702 ± 0.295
2.691AsnTyr: 2.691 ± 0.682
0.0AsnXaa: 0.0 ± 0.0
Pro
4.095ProAla: 4.095 ± 0.656
0.702ProCys: 0.702 ± 0.19
3.744ProAsp: 3.744 ± 0.618
3.861ProGlu: 3.861 ± 0.627
3.159ProPhe: 3.159 ± 0.827
4.095ProGly: 4.095 ± 0.532
1.404ProHis: 1.404 ± 0.435
1.755ProIle: 1.755 ± 0.524
1.287ProLys: 1.287 ± 0.246
7.605ProLeu: 7.605 ± 1.702
1.287ProMet: 1.287 ± 0.46
3.042ProAsn: 3.042 ± 0.518
7.02ProPro: 7.02 ± 1.927
2.574ProGln: 2.574 ± 0.647
4.68ProArg: 4.68 ± 1.149
5.85ProSer: 5.85 ± 0.852
4.095ProThr: 4.095 ± 0.469
4.797ProVal: 4.797 ± 1.091
0.819ProTrp: 0.819 ± 0.348
2.34ProTyr: 2.34 ± 0.596
0.0ProXaa: 0.0 ± 0.0
Gln
3.744GlnAla: 3.744 ± 0.604
0.468GlnCys: 0.468 ± 0.185
1.521GlnAsp: 1.521 ± 0.369
3.042GlnGlu: 3.042 ± 0.587
1.638GlnPhe: 1.638 ± 0.305
2.808GlnGly: 2.808 ± 0.846
0.585GlnHis: 0.585 ± 0.184
1.872GlnIle: 1.872 ± 0.296
1.638GlnLys: 1.638 ± 0.446
4.563GlnLeu: 4.563 ± 0.766
1.17GlnMet: 1.17 ± 0.292
2.457GlnAsn: 2.457 ± 0.667
3.393GlnPro: 3.393 ± 0.64
1.872GlnGln: 1.872 ± 0.457
3.042GlnArg: 3.042 ± 0.599
2.223GlnSer: 2.223 ± 0.522
2.808GlnThr: 2.808 ± 0.591
1.989GlnVal: 1.989 ± 0.345
0.702GlnTrp: 0.702 ± 0.254
1.053GlnTyr: 1.053 ± 0.3
0.0GlnXaa: 0.0 ± 0.0
Arg
5.85ArgAla: 5.85 ± 1.172
1.521ArgCys: 1.521 ± 0.487
2.808ArgAsp: 2.808 ± 0.657
3.51ArgGlu: 3.51 ± 0.821
2.925ArgPhe: 2.925 ± 0.532
6.786ArgGly: 6.786 ± 1.132
1.053ArgHis: 1.053 ± 0.492
2.223ArgIle: 2.223 ± 0.388
1.755ArgLys: 1.755 ± 0.304
6.903ArgLeu: 6.903 ± 1.036
1.053ArgMet: 1.053 ± 0.277
3.744ArgAsn: 3.744 ± 0.646
5.499ArgPro: 5.499 ± 1.342
3.978ArgGln: 3.978 ± 0.62
8.775ArgArg: 8.775 ± 2.929
3.627ArgSer: 3.627 ± 0.716
2.925ArgThr: 2.925 ± 0.608
4.68ArgVal: 4.68 ± 0.848
0.936ArgTrp: 0.936 ± 0.252
2.691ArgTyr: 2.691 ± 0.591
0.0ArgXaa: 0.0 ± 0.0
Ser
5.031SerAla: 5.031 ± 0.706
0.936SerCys: 0.936 ± 0.337
2.691SerAsp: 2.691 ± 0.556
3.861SerGlu: 3.861 ± 0.554
3.042SerPhe: 3.042 ± 0.588
4.68SerGly: 4.68 ± 0.76
0.819SerHis: 0.819 ± 0.306
3.276SerIle: 3.276 ± 0.611
2.223SerLys: 2.223 ± 0.496
9.243SerLeu: 9.243 ± 1.407
1.872SerMet: 1.872 ± 0.555
2.574SerAsn: 2.574 ± 0.557
4.212SerPro: 4.212 ± 0.898
2.691SerGln: 2.691 ± 0.421
5.382SerArg: 5.382 ± 0.623
5.85SerSer: 5.85 ± 0.945
5.265SerThr: 5.265 ± 0.758
4.329SerVal: 4.329 ± 0.734
0.936SerTrp: 0.936 ± 0.332
2.925SerTyr: 2.925 ± 0.663
0.0SerXaa: 0.0 ± 0.0
Thr
4.797ThrAla: 4.797 ± 0.75
0.819ThrCys: 0.819 ± 0.318
2.925ThrAsp: 2.925 ± 0.677
3.393ThrGlu: 3.393 ± 0.541
2.925ThrPhe: 2.925 ± 0.874
2.808ThrGly: 2.808 ± 0.584
0.936ThrHis: 0.936 ± 0.345
3.393ThrIle: 3.393 ± 0.764
1.521ThrLys: 1.521 ± 0.45
6.786ThrLeu: 6.786 ± 0.965
1.053ThrMet: 1.053 ± 0.391
3.042ThrAsn: 3.042 ± 0.929
4.446ThrPro: 4.446 ± 0.848
2.574ThrGln: 2.574 ± 0.439
2.574ThrArg: 2.574 ± 0.602
3.978ThrSer: 3.978 ± 1.076
3.393ThrThr: 3.393 ± 0.811
4.212ThrVal: 4.212 ± 0.601
1.053ThrTrp: 1.053 ± 0.375
2.223ThrTyr: 2.223 ± 0.75
0.0ThrXaa: 0.0 ± 0.0
Val
4.212ValAla: 4.212 ± 0.884
1.053ValCys: 1.053 ± 0.341
4.329ValAsp: 4.329 ± 0.552
4.212ValGlu: 4.212 ± 0.687
3.276ValPhe: 3.276 ± 0.627
3.042ValGly: 3.042 ± 0.517
1.17ValHis: 1.17 ± 0.408
1.989ValIle: 1.989 ± 0.614
2.691ValLys: 2.691 ± 0.512
5.967ValLeu: 5.967 ± 0.734
1.755ValMet: 1.755 ± 0.415
2.574ValAsn: 2.574 ± 0.401
4.446ValPro: 4.446 ± 0.609
2.925ValGln: 2.925 ± 0.542
4.914ValArg: 4.914 ± 0.973
4.797ValSer: 4.797 ± 0.493
5.733ValThr: 5.733 ± 0.806
4.563ValVal: 4.563 ± 0.933
0.351ValTrp: 0.351 ± 0.169
3.51ValTyr: 3.51 ± 0.607
0.0ValXaa: 0.0 ± 0.0
Trp
0.702TrpAla: 0.702 ± 0.264
0.0TrpCys: 0.0 ± 0.0
0.702TrpAsp: 0.702 ± 0.231
1.638TrpGlu: 1.638 ± 0.348
0.585TrpPhe: 0.585 ± 0.281
1.287TrpGly: 1.287 ± 0.322
0.117TrpHis: 0.117 ± 0.095
0.468TrpIle: 0.468 ± 0.253
0.702TrpLys: 0.702 ± 0.259
0.936TrpLeu: 0.936 ± 0.248
0.117TrpMet: 0.117 ± 0.104
1.053TrpAsn: 1.053 ± 0.369
0.702TrpPro: 0.702 ± 0.246
0.234TrpGln: 0.234 ± 0.171
0.936TrpArg: 0.936 ± 0.34
1.521TrpSer: 1.521 ± 0.308
0.702TrpThr: 0.702 ± 0.247
0.234TrpVal: 0.234 ± 0.175
0.117TrpTrp: 0.117 ± 0.114
0.234TrpTyr: 0.234 ± 0.176
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.457TyrAla: 2.457 ± 0.637
0.351TyrCys: 0.351 ± 0.156
1.638TyrAsp: 1.638 ± 0.457
1.872TyrGlu: 1.872 ± 0.549
1.872TyrPhe: 1.872 ± 0.54
2.223TyrGly: 2.223 ± 0.584
0.468TyrHis: 0.468 ± 0.356
1.053TyrIle: 1.053 ± 0.342
1.17TyrLys: 1.17 ± 0.278
4.095TyrLeu: 4.095 ± 0.606
1.287TyrMet: 1.287 ± 0.389
2.457TyrAsn: 2.457 ± 0.637
1.989TyrPro: 1.989 ± 0.483
1.989TyrGln: 1.989 ± 0.656
2.223TyrArg: 2.223 ± 0.403
3.042TyrSer: 3.042 ± 0.712
2.457TyrThr: 2.457 ± 0.479
2.457TyrVal: 2.457 ± 0.626
0.468TyrTrp: 0.468 ± 0.213
0.468TyrTyr: 0.468 ± 0.195
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 23 proteins (8548 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski