Amino acid dipepetide frequency for Clostridium tarantellae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.753AlaAla: 2.753 ± 0.076	0.578AlaCys: 0.578 ± 0.029	2.166AlaAsp: 2.166 ± 0.05	2.936AlaGlu: 2.936 ± 0.124	2.211AlaPhe: 2.211 ± 0.059	3.059AlaGly: 3.059 ± 0.075	0.785AlaHis: 0.785 ± 0.032	5.528AlaIle: 5.528 ± 0.089	4.494AlaLys: 4.494 ± 0.077	5.464AlaLeu: 5.464 ± 0.083	1.364AlaMet: 1.364 ± 0.042	2.998AlaAsn: 2.998 ± 0.068	1.412AlaPro: 1.412 ± 0.044	1.173AlaGln: 1.173 ± 0.039	1.517AlaArg: 1.517 ± 0.038	2.899AlaSer: 2.899 ± 0.065	3.037AlaThr: 3.037 ± 0.059	3.091AlaVal: 3.091 ± 0.071	0.389AlaTrp: 0.389 ± 0.021	2.016AlaTyr: 2.016 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.519CysAla: 0.519 ± 0.023	0.274CysCys: 0.274 ± 0.031	0.644CysAsp: 0.644 ± 0.028	0.807CysGlu: 0.807 ± 0.03	0.518CysPhe: 0.518 ± 0.024	0.951CysGly: 0.951 ± 0.037	0.179CysHis: 0.179 ± 0.014	1.125CysIle: 1.125 ± 0.038	1.076CysLys: 1.076 ± 0.035	0.856CysLeu: 0.856 ± 0.032	0.236CysMet: 0.236 ± 0.015	0.859CysAsn: 0.859 ± 0.028	0.382CysPro: 0.382 ± 0.019	0.194CysGln: 0.194 ± 0.013	0.337CysArg: 0.337 ± 0.021	0.76CysSer: 0.76 ± 0.034	0.57CysThr: 0.57 ± 0.023	0.606CysVal: 0.606 ± 0.022	0.069CysTrp: 0.069 ± 0.008	0.45CysTyr: 0.45 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	2.279AspAla: 2.279 ± 0.054	0.614AspCys: 0.614 ± 0.024	2.386AspAsp: 2.386 ± 0.054	4.132AspGlu: 4.132 ± 0.067	2.888AspPhe: 2.888 ± 0.054	3.48AspGly: 3.48 ± 0.1	0.476AspHis: 0.476 ± 0.022	6.051AspIle: 6.051 ± 0.091	5.367AspLys: 5.367 ± 0.088	5.107AspLeu: 5.107 ± 0.065	1.208AspMet: 1.208 ± 0.032	3.829AspAsn: 3.829 ± 0.074	1.179AspPro: 1.179 ± 0.038	0.621AspGln: 0.621 ± 0.026	1.532AspArg: 1.532 ± 0.039	3.232AspSer: 3.232 ± 0.065	2.335AspThr: 2.335 ± 0.057	3.237AspVal: 3.237 ± 0.061	0.393AspTrp: 0.393 ± 0.021	2.612AspTyr: 2.612 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	3.523GluAla: 3.523 ± 0.067	0.727GluCys: 0.727 ± 0.029	4.025GluAsp: 4.025 ± 0.084	6.684GluGlu: 6.684 ± 0.126	3.363GluPhe: 3.363 ± 0.055	4.442GluGly: 4.442 ± 0.147	0.837GluHis: 0.837 ± 0.03	7.08GluIle: 7.08 ± 0.089	7.993GluLys: 7.993 ± 0.13	6.759GluLeu: 6.759 ± 0.103	1.591GluMet: 1.591 ± 0.045	6.171GluAsn: 6.171 ± 0.095	1.36GluPro: 1.36 ± 0.037	1.735GluGln: 1.735 ± 0.044	2.195GluArg: 2.195 ± 0.047	3.48GluSer: 3.48 ± 0.059	2.877GluThr: 2.877 ± 0.062	4.707GluVal: 4.707 ± 0.07	0.446GluTrp: 0.446 ± 0.022	3.152GluTyr: 3.152 ± 0.065	0.0GluXaa: 0.0 ± 0.0
Phe	2.041PheAla: 2.041 ± 0.043	0.527PheCys: 0.527 ± 0.026	2.439PheAsp: 2.439 ± 0.054	2.691PheGlu: 2.691 ± 0.058	2.127PhePhe: 2.127 ± 0.066	2.521PheGly: 2.521 ± 0.058	0.67PheHis: 0.67 ± 0.028	5.23PheIle: 5.23 ± 0.098	4.707PheLys: 4.707 ± 0.074	4.107PheLeu: 4.107 ± 0.075	1.09PheMet: 1.09 ± 0.034	4.064PheAsn: 4.064 ± 0.063	1.137PhePro: 1.137 ± 0.036	1.049PheGln: 1.049 ± 0.033	1.152PheArg: 1.152 ± 0.03	3.258PheSer: 3.258 ± 0.063	2.5PheThr: 2.5 ± 0.058	2.338PheVal: 2.338 ± 0.059	0.305PheTrp: 0.305 ± 0.02	1.947PheTyr: 1.947 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	3.768GlyAla: 3.768 ± 0.083	0.769GlyCys: 0.769 ± 0.035	3.363GlyAsp: 3.363 ± 0.083	4.479GlyGlu: 4.479 ± 0.089	2.914GlyPhe: 2.914 ± 0.063	3.776GlyGly: 3.776 ± 0.081	0.852GlyHis: 0.852 ± 0.033	6.532GlyIle: 6.532 ± 0.091	5.459GlyLys: 5.459 ± 0.077	4.904GlyLeu: 4.904 ± 0.089	1.439GlyMet: 1.439 ± 0.04	4.023GlyAsn: 4.023 ± 0.098	1.157GlyPro: 1.157 ± 0.039	1.348GlyGln: 1.348 ± 0.034	2.023GlyArg: 2.023 ± 0.053	3.438GlySer: 3.438 ± 0.071	3.518GlyThr: 3.518 ± 0.076	4.463GlyVal: 4.463 ± 0.087	0.542GlyTrp: 0.542 ± 0.028	2.682GlyTyr: 2.682 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	0.743HisAla: 0.743 ± 0.107	0.179HisCys: 0.179 ± 0.011	0.609HisAsp: 0.609 ± 0.025	0.802HisGlu: 0.802 ± 0.03	0.587HisPhe: 0.587 ± 0.023	0.975HisGly: 0.975 ± 0.035	0.247HisHis: 0.247 ± 0.016	1.407HisIle: 1.407 ± 0.035	1.095HisLys: 1.095 ± 0.03	1.116HisLeu: 1.116 ± 0.034	0.312HisMet: 0.312 ± 0.016	0.885HisAsn: 0.885 ± 0.026	0.518HisPro: 0.518 ± 0.021	0.25HisGln: 0.25 ± 0.017	0.443HisArg: 0.443 ± 0.022	0.819HisSer: 0.819 ± 0.04	0.677HisThr: 0.677 ± 0.025	0.68HisVal: 0.68 ± 0.026	0.131HisTrp: 0.131 ± 0.014	0.519HisTyr: 0.519 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.294IleAla: 5.294 ± 0.104	1.262IleCys: 1.262 ± 0.041	5.828IleAsp: 5.828 ± 0.087	7.325IleGlu: 7.325 ± 0.099	4.613IlePhe: 4.613 ± 0.088	6.14IleGly: 6.14 ± 0.092	1.229IleHis: 1.229 ± 0.04	10.259IleIle: 10.259 ± 0.148	10.434IleLys: 10.434 ± 0.121	9.467IleLeu: 9.467 ± 0.13	2.1IleMet: 2.1 ± 0.049	8.428IleAsn: 8.428 ± 0.098	3.379IlePro: 3.379 ± 0.07	2.108IleGln: 2.108 ± 0.048	2.626IleArg: 2.626 ± 0.051	7.171IleSer: 7.171 ± 0.098	5.624IleThr: 5.624 ± 0.107	5.808IleVal: 5.808 ± 0.081	0.58IleTrp: 0.58 ± 0.027	4.067IleTyr: 4.067 ± 0.085	0.0IleXaa: 0.0 ± 0.0
Lys	4.68LysAla: 4.68 ± 0.075	0.932LysCys: 0.932 ± 0.034	6.177LysAsp: 6.177 ± 0.09	9.553LysGlu: 9.553 ± 0.13	4.049LysPhe: 4.049 ± 0.072	5.19LysGly: 5.19 ± 0.079	1.125LysHis: 1.125 ± 0.033	9.538LysIle: 9.538 ± 0.128	9.0LysLys: 9.0 ± 0.122	8.041LysLeu: 8.041 ± 0.104	2.028LysMet: 2.028 ± 0.051	8.113LysAsn: 8.113 ± 0.122	2.173LysPro: 2.173 ± 0.058	2.009LysGln: 2.009 ± 0.042	2.697LysArg: 2.697 ± 0.07	5.36LysSer: 5.36 ± 0.077	4.367LysThr: 4.367 ± 0.068	6.394LysVal: 6.394 ± 0.1	0.646LysTrp: 0.646 ± 0.033	4.436LysTyr: 4.436 ± 0.067	0.0LysXaa: 0.0 ± 0.0
Leu	4.831LeuAla: 4.831 ± 0.078	1.036LeuCys: 1.036 ± 0.035	4.922LeuAsp: 4.922 ± 0.073	6.389LeuGlu: 6.389 ± 0.091	3.64LeuPhe: 3.64 ± 0.071	5.914LeuGly: 5.914 ± 0.094	1.005LeuHis: 1.005 ± 0.035	8.996LeuIle: 8.996 ± 0.129	9.303LeuLys: 9.303 ± 0.123	7.416LeuLeu: 7.416 ± 0.124	2.058LeuMet: 2.058 ± 0.049	7.582LeuAsn: 7.582 ± 0.109	2.769LeuPro: 2.769 ± 0.057	2.086LeuGln: 2.086 ± 0.043	2.628LeuArg: 2.628 ± 0.056	6.375LeuSer: 6.375 ± 0.092	4.698LeuThr: 4.698 ± 0.07	5.014LeuVal: 5.014 ± 0.078	0.603LeuTrp: 0.603 ± 0.025	3.407LeuTyr: 3.407 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	1.395MetAla: 1.395 ± 0.042	0.25MetCys: 0.25 ± 0.013	1.29MetAsp: 1.29 ± 0.035	1.554MetGlu: 1.554 ± 0.038	0.937MetPhe: 0.937 ± 0.033	1.491MetGly: 1.491 ± 0.042	0.302MetHis: 0.302 ± 0.018	2.021MetIle: 2.021 ± 0.043	2.231MetLys: 2.231 ± 0.058	1.946MetLeu: 1.946 ± 0.048	0.533MetMet: 0.533 ± 0.026	1.661MetAsn: 1.661 ± 0.039	0.743MetPro: 0.743 ± 0.027	0.59MetGln: 0.59 ± 0.024	0.7MetArg: 0.7 ± 0.026	1.429MetSer: 1.429 ± 0.037	0.953MetThr: 0.953 ± 0.032	1.392MetVal: 1.392 ± 0.04	0.174MetTrp: 0.174 ± 0.013	0.803MetTyr: 0.803 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.103AsnAla: 3.103 ± 0.066	0.785AsnCys: 0.785 ± 0.03	3.556AsnAsp: 3.556 ± 0.064	5.779AsnGlu: 5.779 ± 0.095	3.669AsnPhe: 3.669 ± 0.06	4.638AsnGly: 4.638 ± 0.121	0.892AsnHis: 0.892 ± 0.027	8.919AsnIle: 8.919 ± 0.112	8.426AsnLys: 8.426 ± 0.116	7.177AsnLeu: 7.177 ± 0.105	1.716AsnMet: 1.716 ± 0.045	6.922AsnAsn: 6.922 ± 0.137	2.217AsnPro: 2.217 ± 0.046	1.163AsnGln: 1.163 ± 0.032	1.989AsnArg: 1.989 ± 0.042	4.954AsnSer: 4.954 ± 0.112	3.858AsnThr: 3.858 ± 0.094	3.958AsnVal: 3.958 ± 0.071	0.606AsnTrp: 0.606 ± 0.026	3.23AsnTyr: 3.23 ± 0.056	0.0AsnXaa: 0.0 ± 0.0
Pro	1.25ProAla: 1.25 ± 0.038	0.313ProCys: 0.313 ± 0.019	1.22ProAsp: 1.22 ± 0.041	1.889ProGlu: 1.889 ± 0.051	1.363ProPhe: 1.363 ± 0.037	1.581ProGly: 1.581 ± 0.05	0.463ProHis: 0.463 ± 0.021	2.862ProIle: 2.862 ± 0.065	2.344ProLys: 2.344 ± 0.05	2.462ProLeu: 2.462 ± 0.05	0.668ProMet: 0.668 ± 0.025	2.056ProAsn: 2.056 ± 0.06	0.682ProPro: 0.682 ± 0.046	0.725ProGln: 0.725 ± 0.03	0.701ProArg: 0.701 ± 0.025	1.872ProSer: 1.872 ± 0.047	1.634ProThr: 1.634 ± 0.057	1.802ProVal: 1.802 ± 0.044	0.275ProTrp: 0.275 ± 0.014	1.268ProTyr: 1.268 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	1.181GlnAla: 1.181 ± 0.042	0.292GlnCys: 0.292 ± 0.017	1.001GlnAsp: 1.001 ± 0.033	1.358GlnGlu: 1.358 ± 0.042	0.944GlnPhe: 0.944 ± 0.034	1.374GlnGly: 1.374 ± 0.039	0.264GlnHis: 0.264 ± 0.017	2.046GlnIle: 2.046 ± 0.044	1.713GlnLys: 1.713 ± 0.049	1.981GlnLeu: 1.981 ± 0.042	0.498GlnMet: 0.498 ± 0.023	1.384GlnAsn: 1.384 ± 0.04	0.61GlnPro: 0.61 ± 0.025	0.56GlnGln: 0.56 ± 0.024	0.719GlnArg: 0.719 ± 0.027	1.296GlnSer: 1.296 ± 0.042	1.007GlnThr: 1.007 ± 0.037	1.357GlnVal: 1.357 ± 0.035	0.236GlnTrp: 0.236 ± 0.018	1.024GlnTyr: 1.024 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	1.495ArgAla: 1.495 ± 0.042	0.354ArgCys: 0.354 ± 0.018	1.591ArgAsp: 1.591 ± 0.034	2.424ArgGlu: 2.424 ± 0.061	1.293ArgPhe: 1.293 ± 0.035	1.645ArgGly: 1.645 ± 0.043	0.374ArgHis: 0.374 ± 0.021	2.763ArgIle: 2.763 ± 0.053	2.73ArgLys: 2.73 ± 0.058	2.467ArgLeu: 2.467 ± 0.055	0.722ArgMet: 0.722 ± 0.029	1.897ArgAsn: 1.897 ± 0.048	0.766ArgPro: 0.766 ± 0.033	0.687ArgGln: 0.687 ± 0.025	1.094ArgArg: 1.094 ± 0.036	1.367ArgSer: 1.367 ± 0.044	1.45ArgThr: 1.45 ± 0.04	1.963ArgVal: 1.963 ± 0.046	0.26ArgTrp: 0.26 ± 0.017	1.255ArgTyr: 1.255 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	2.741SerAla: 2.741 ± 0.058	0.616SerCys: 0.616 ± 0.027	2.867SerAsp: 2.867 ± 0.054	3.754SerGlu: 3.754 ± 0.076	3.178SerPhe: 3.178 ± 0.058	3.897SerGly: 3.897 ± 0.098	1.113SerHis: 1.113 ± 0.123	6.852SerIle: 6.852 ± 0.092	6.014SerLys: 6.014 ± 0.088	6.219SerLeu: 6.219 ± 0.086	1.431SerMet: 1.431 ± 0.038	4.887SerAsn: 4.887 ± 0.094	1.652SerPro: 1.652 ± 0.046	1.404SerGln: 1.404 ± 0.03	1.683SerArg: 1.683 ± 0.042	4.423SerSer: 4.423 ± 0.108	3.601SerThr: 3.601 ± 0.092	3.487SerVal: 3.487 ± 0.065	0.498SerTrp: 0.498 ± 0.026	2.626SerTyr: 2.626 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	2.67ThrAla: 2.67 ± 0.059	0.493ThrCys: 0.493 ± 0.02	2.508ThrAsp: 2.508 ± 0.064	2.978ThrGlu: 2.978 ± 0.059	2.453ThrPhe: 2.453 ± 0.055	3.528ThrGly: 3.528 ± 0.069	0.735ThrHis: 0.735 ± 0.027	5.634ThrIle: 5.634 ± 0.102	3.981ThrLys: 3.981 ± 0.059	5.483ThrLeu: 5.483 ± 0.086	1.061ThrMet: 1.061 ± 0.032	3.464ThrAsn: 3.464 ± 0.075	2.027ThrPro: 2.027 ± 0.058	1.025ThrGln: 1.025 ± 0.041	1.306ThrArg: 1.306 ± 0.038	3.467ThrSer: 3.467 ± 0.083	3.037ThrThr: 3.037 ± 0.086	3.484ThrVal: 3.484 ± 0.095	0.4ThrTrp: 0.4 ± 0.025	2.048ThrTyr: 2.048 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	3.3ValAla: 3.3 ± 0.071	0.75ValCys: 0.75 ± 0.031	3.621ValAsp: 3.621 ± 0.068	4.155ValGlu: 4.155 ± 0.077	2.675ValPhe: 2.675 ± 0.055	3.807ValGly: 3.807 ± 0.07	0.751ValHis: 0.751 ± 0.03	5.924ValIle: 5.924 ± 0.092	5.594ValLys: 5.594 ± 0.074	5.34ValLeu: 5.34 ± 0.076	1.241ValMet: 1.241 ± 0.034	4.328ValAsn: 4.328 ± 0.09	1.949ValPro: 1.949 ± 0.042	1.27ValGln: 1.27 ± 0.036	1.74ValArg: 1.74 ± 0.057	3.935ValSer: 3.935 ± 0.07	3.397ValThr: 3.397 ± 0.086	3.818ValVal: 3.818 ± 0.076	0.372ValTrp: 0.372 ± 0.021	2.353ValTyr: 2.353 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.39TrpAla: 0.39 ± 0.023	0.099TrpCys: 0.099 ± 0.011	0.407TrpAsp: 0.407 ± 0.025	0.448TrpGlu: 0.448 ± 0.022	0.298TrpPhe: 0.298 ± 0.015	0.486TrpGly: 0.486 ± 0.026	0.163TrpHis: 0.163 ± 0.013	0.73TrpIle: 0.73 ± 0.03	0.487TrpLys: 0.487 ± 0.023	0.581TrpLeu: 0.581 ± 0.022	0.181TrpMet: 0.181 ± 0.014	0.627TrpAsn: 0.627 ± 0.027	0.157TrpPro: 0.157 ± 0.012	0.246TrpGln: 0.246 ± 0.02	0.242TrpArg: 0.242 ± 0.016	0.524TrpSer: 0.524 ± 0.027	0.423TrpThr: 0.423 ± 0.024	0.446TrpVal: 0.446 ± 0.025	0.097TrpTrp: 0.097 ± 0.011	0.328TrpTyr: 0.328 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.916TyrAla: 1.916 ± 0.047	0.562TyrCys: 0.562 ± 0.024	2.338TyrAsp: 2.338 ± 0.06	3.007TyrGlu: 3.007 ± 0.065	2.18TyrPhe: 2.18 ± 0.05	2.555TyrGly: 2.555 ± 0.049	0.531TyrHis: 0.531 ± 0.023	4.245TyrIle: 4.245 ± 0.071	4.059TyrLys: 4.059 ± 0.072	3.78TyrLeu: 3.78 ± 0.073	0.918TyrMet: 0.918 ± 0.032	3.38TyrAsn: 3.38 ± 0.068	1.162TyrPro: 1.162 ± 0.036	0.599TyrGln: 0.599 ± 0.022	1.273TyrArg: 1.273 ± 0.035	2.884TyrSer: 2.884 ± 0.066	2.219TyrThr: 2.219 ± 0.051	2.278TyrVal: 2.278 ± 0.052	0.339TyrTrp: 0.339 ± 0.019	1.897TyrTyr: 1.897 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3225 proteins (1102011 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---