Simian cytomegalovirus (strain Colburn)

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus

Average proteome isoelectric point is 7.1

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 175 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G8XU18|G8XU18_SCMVC Membrane protein UL147A OS=Simian cytomegalovirus (strain Colburn) OX=50292 GN=UL147A PE=4 SV=1
MM1 pKa = 7.96KK2 pKa = 10.19DD3 pKa = 3.28RR4 pKa = 11.84LSICCLCLSLVAHH17 pKa = 7.07LNQATQGTVSEE28 pKa = 5.09DD29 pKa = 3.14NDD31 pKa = 4.07NINGIGPLTSSAMGLNTQPPGSVMALAVHH60 pKa = 6.42TASSSPSSAVLPTVLALSGMVLVVLLMIGLNISSTFWSQEE100 pKa = 3.46VDD102 pKa = 3.11EE103 pKa = 5.47DD104 pKa = 4.4ALDD107 pKa = 3.82TATTPVEE114 pKa = 4.58VYY116 pKa = 9.9TVDD119 pKa = 3.85LCVKK123 pKa = 8.79TVV125 pKa = 2.72

Molecular weight: 12.98 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G8XU72|G8XU72_SCMVC Tegument protein TRS1 OS=Simian cytomegalovirus (strain Colburn) OX=50292 GN=TRS1 PE=4 SV=1
MM1 pKa = 7.71ARR3 pKa = 11.84LTPMQHH9 pKa = 5.77LRR11 pKa = 11.84AALRR15 pKa = 11.84GWWNNFLNMFRR26 pKa = 11.84RR27 pKa = 11.84RR28 pKa = 11.84SRR30 pKa = 11.84QKK32 pKa = 10.78PEE34 pKa = 3.7GQTPPRR40 pKa = 11.84LPHH43 pKa = 6.63ALRR46 pKa = 11.84DD47 pKa = 3.83VLEE50 pKa = 4.95KK51 pKa = 10.91YY52 pKa = 9.74WNTCADD58 pKa = 4.36FVRR61 pKa = 11.84QEE63 pKa = 4.51AKK65 pKa = 10.52PKK67 pKa = 9.13ATPKK71 pKa = 10.75DD72 pKa = 3.34GFDD75 pKa = 5.19FYY77 pKa = 11.59LQTLKK82 pKa = 10.93DD83 pKa = 4.03ALRR86 pKa = 11.84EE87 pKa = 4.27TPSGAQTVHH96 pKa = 6.39GFVNPCYY103 pKa = 10.16LLNLFTPAQTRR114 pKa = 11.84RR115 pKa = 11.84NSRR118 pKa = 3.14

Molecular weight: 13.86 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

175

0

175

59368

55

2170

339.2

38.37

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.675 ± 0.182

2.72 ± 0.128

4.796 ± 0.14

5.372 ± 0.172

4.117 ± 0.12

4.676 ± 0.14

2.975 ± 0.114

5.045 ± 0.149

3.987 ± 0.179

10.063 ± 0.174

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.493 ± 0.086

4.218 ± 0.131

5.614 ± 0.189

3.852 ± 0.176

6.537 ± 0.188

7.524 ± 0.187

7.208 ± 0.276

7.155 ± 0.154

1.354 ± 0.082

3.62 ± 0.111
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski