Amino acid dipepetide frequency for Halomonas ilicicola DSM 19980

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.666AlaAla: 11.666 ± 0.119	1.179AlaCys: 1.179 ± 0.035	5.662AlaAsp: 5.662 ± 0.071	7.121AlaGlu: 7.121 ± 0.093	3.925AlaPhe: 3.925 ± 0.066	9.101AlaGly: 9.101 ± 0.102	2.132AlaHis: 2.132 ± 0.047	5.604AlaIle: 5.604 ± 0.075	2.758AlaLys: 2.758 ± 0.048	14.051AlaLeu: 14.051 ± 0.156	3.178AlaMet: 3.178 ± 0.059	2.545AlaAsn: 2.545 ± 0.056	4.661AlaPro: 4.661 ± 0.062	4.06AlaGln: 4.06 ± 0.072	8.454AlaArg: 8.454 ± 0.096	6.303AlaSer: 6.303 ± 0.087	5.425AlaThr: 5.425 ± 0.067	7.272AlaVal: 7.272 ± 0.079	1.92AlaTrp: 1.92 ± 0.048	2.432AlaTyr: 2.432 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.921CysAla: 0.921 ± 0.034	0.128CysCys: 0.128 ± 0.011	0.528CysAsp: 0.528 ± 0.021	0.531CysGlu: 0.531 ± 0.023	0.351CysPhe: 0.351 ± 0.015	0.925CysGly: 0.925 ± 0.029	0.358CysHis: 0.358 ± 0.021	0.386CysIle: 0.386 ± 0.019	0.201CysLys: 0.201 ± 0.013	1.035CysLeu: 1.035 ± 0.031	0.181CysMet: 0.181 ± 0.012	0.225CysAsn: 0.225 ± 0.013	0.539CysPro: 0.539 ± 0.024	0.356CysGln: 0.356 ± 0.017	0.744CysArg: 0.744 ± 0.026	0.457CysSer: 0.457 ± 0.021	0.383CysThr: 0.383 ± 0.018	0.571CysVal: 0.571 ± 0.021	0.121CysTrp: 0.121 ± 0.01	0.235CysTyr: 0.235 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.467AspAla: 6.467 ± 0.088	0.474AspCys: 0.474 ± 0.023	3.94AspAsp: 3.94 ± 0.073	4.42AspGlu: 4.42 ± 0.07	2.106AspPhe: 2.106 ± 0.044	4.692AspGly: 4.692 ± 0.089	1.403AspHis: 1.403 ± 0.036	3.01AspIle: 3.01 ± 0.06	1.762AspLys: 1.762 ± 0.044	5.483AspLeu: 5.483 ± 0.081	1.309AspMet: 1.309 ± 0.032	1.612AspAsn: 1.612 ± 0.046	3.092AspPro: 3.092 ± 0.06	1.977AspGln: 1.977 ± 0.04	3.898AspArg: 3.898 ± 0.059	2.81AspSer: 2.81 ± 0.053	3.0AspThr: 3.0 ± 0.054	3.848AspVal: 3.848 ± 0.065	1.03AspTrp: 1.03 ± 0.029	1.865AspTyr: 1.865 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	8.171GluAla: 8.171 ± 0.104	0.483GluCys: 0.483 ± 0.021	3.114GluAsp: 3.114 ± 0.059	4.266GluGlu: 4.266 ± 0.075	1.831GluPhe: 1.831 ± 0.043	4.976GluGly: 4.976 ± 0.072	1.798GluHis: 1.798 ± 0.045	3.15GluIle: 3.15 ± 0.059	2.02GluLys: 2.02 ± 0.045	7.007GluLeu: 7.007 ± 0.087	1.507GluMet: 1.507 ± 0.033	1.662GluAsn: 1.662 ± 0.044	2.824GluPro: 2.824 ± 0.05	3.239GluGln: 3.239 ± 0.063	6.222GluArg: 6.222 ± 0.083	3.266GluSer: 3.266 ± 0.057	3.489GluThr: 3.489 ± 0.056	4.648GluVal: 4.648 ± 0.072	0.863GluTrp: 0.863 ± 0.028	1.313GluTyr: 1.313 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.736PheAla: 3.736 ± 0.059	0.393PheCys: 0.393 ± 0.018	2.601PheAsp: 2.601 ± 0.056	2.319PheGlu: 2.319 ± 0.04	1.432PhePhe: 1.432 ± 0.041	3.121PheGly: 3.121 ± 0.057	0.805PheHis: 0.805 ± 0.027	1.788PheIle: 1.788 ± 0.039	0.954PheLys: 0.954 ± 0.03	3.352PheLeu: 3.352 ± 0.064	0.831PheMet: 0.831 ± 0.028	1.064PheAsn: 1.064 ± 0.032	1.432PhePro: 1.432 ± 0.035	1.099PheGln: 1.099 ± 0.027	1.99PheArg: 1.99 ± 0.039	2.228PheSer: 2.228 ± 0.046	1.942PheThr: 1.942 ± 0.046	2.527PheVal: 2.527 ± 0.052	0.506PheTrp: 0.506 ± 0.022	0.938PheTyr: 0.938 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	7.517GlyAla: 7.517 ± 0.095	0.9GlyCys: 0.9 ± 0.029	4.712GlyAsp: 4.712 ± 0.082	5.741GlyGlu: 5.741 ± 0.071	3.178GlyPhe: 3.178 ± 0.052	6.639GlyGly: 6.639 ± 0.105	2.07GlyHis: 2.07 ± 0.053	4.591GlyIle: 4.591 ± 0.07	2.796GlyLys: 2.796 ± 0.055	9.383GlyLeu: 9.383 ± 0.111	2.488GlyMet: 2.488 ± 0.048	2.248GlyAsn: 2.248 ± 0.057	2.857GlyPro: 2.857 ± 0.055	3.196GlyGln: 3.196 ± 0.055	5.583GlyArg: 5.583 ± 0.078	4.387GlySer: 4.387 ± 0.077	3.844GlyThr: 3.844 ± 0.058	6.323GlyVal: 6.323 ± 0.086	1.478GlyTrp: 1.478 ± 0.036	2.409GlyTyr: 2.409 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.613HisAla: 2.613 ± 0.052	0.327HisCys: 0.327 ± 0.018	1.459HisAsp: 1.459 ± 0.032	1.345HisGlu: 1.345 ± 0.039	0.986HisPhe: 0.986 ± 0.026	2.211HisGly: 2.211 ± 0.047	0.788HisHis: 0.788 ± 0.031	0.903HisIle: 0.903 ± 0.03	0.537HisLys: 0.537 ± 0.02	2.682HisLeu: 2.682 ± 0.052	0.458HisMet: 0.458 ± 0.021	0.576HisAsn: 0.576 ± 0.023	1.545HisPro: 1.545 ± 0.04	0.941HisGln: 0.941 ± 0.028	1.909HisArg: 1.909 ± 0.044	1.101HisSer: 1.101 ± 0.034	0.956HisThr: 0.956 ± 0.028	1.491HisVal: 1.491 ± 0.04	0.45HisTrp: 0.45 ± 0.021	0.793HisTyr: 0.793 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.06IleAla: 6.06 ± 0.082	0.404IleCys: 0.404 ± 0.018	3.845IleAsp: 3.845 ± 0.066	3.73IleGlu: 3.73 ± 0.052	1.477IlePhe: 1.477 ± 0.038	4.506IleGly: 4.506 ± 0.074	1.053IleHis: 1.053 ± 0.03	1.972IleIle: 1.972 ± 0.049	1.378IleLys: 1.378 ± 0.038	4.364IleLeu: 4.364 ± 0.073	0.897IleMet: 0.897 ± 0.028	1.49IleAsn: 1.49 ± 0.033	2.33IlePro: 2.33 ± 0.048	1.414IleGln: 1.414 ± 0.038	2.984IleArg: 2.984 ± 0.047	2.583IleSer: 2.583 ± 0.052	2.569IleThr: 2.569 ± 0.052	3.567IleVal: 3.567 ± 0.054	0.495IleTrp: 0.495 ± 0.019	1.075IleTyr: 1.075 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.164LysAla: 3.164 ± 0.057	0.163LysCys: 0.163 ± 0.012	1.285LysAsp: 1.285 ± 0.036	1.672LysGlu: 1.672 ± 0.046	0.625LysPhe: 0.625 ± 0.024	2.262LysGly: 2.262 ± 0.047	0.647LysHis: 0.647 ± 0.023	1.226LysIle: 1.226 ± 0.04	1.032LysLys: 1.032 ± 0.038	2.86LysLeu: 2.86 ± 0.054	0.617LysMet: 0.617 ± 0.025	0.731LysAsn: 0.731 ± 0.028	1.524LysPro: 1.524 ± 0.039	1.252LysGln: 1.252 ± 0.033	2.411LysArg: 2.411 ± 0.05	1.503LysSer: 1.503 ± 0.04	1.479LysThr: 1.479 ± 0.037	2.072LysVal: 2.072 ± 0.045	0.293LysTrp: 0.293 ± 0.017	0.56LysTyr: 0.56 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.424LeuAla: 14.424 ± 0.145	1.004LeuCys: 1.004 ± 0.032	7.337LeuAsp: 7.337 ± 0.089	7.932LeuGlu: 7.932 ± 0.089	4.084LeuPhe: 4.084 ± 0.083	9.596LeuGly: 9.596 ± 0.121	2.357LeuHis: 2.357 ± 0.049	5.731LeuIle: 5.731 ± 0.084	3.391LeuLys: 3.391 ± 0.058	12.657LeuLeu: 12.657 ± 0.184	2.796LeuMet: 2.796 ± 0.049	2.901LeuAsn: 2.901 ± 0.06	6.089LeuPro: 6.089 ± 0.088	3.345LeuGln: 3.345 ± 0.06	7.236LeuArg: 7.236 ± 0.09	6.586LeuSer: 6.586 ± 0.084	5.751LeuThr: 5.751 ± 0.079	8.072LeuVal: 8.072 ± 0.12	1.62LeuTrp: 1.62 ± 0.047	2.437LeuTyr: 2.437 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.085MetAla: 3.085 ± 0.055	0.154MetCys: 0.154 ± 0.011	1.072MetAsp: 1.072 ± 0.033	1.169MetGlu: 1.169 ± 0.03	0.696MetPhe: 0.696 ± 0.027	1.812MetGly: 1.812 ± 0.051	0.53MetHis: 0.53 ± 0.022	1.286MetIle: 1.286 ± 0.034	0.822MetLys: 0.822 ± 0.027	2.806MetLeu: 2.806 ± 0.055	0.676MetMet: 0.676 ± 0.032	0.82MetAsn: 0.82 ± 0.025	1.486MetPro: 1.486 ± 0.038	1.0MetGln: 1.0 ± 0.029	1.605MetArg: 1.605 ± 0.038	1.717MetSer: 1.717 ± 0.033	1.676MetThr: 1.676 ± 0.04	1.637MetVal: 1.637 ± 0.043	0.203MetTrp: 0.203 ± 0.013	0.347MetTyr: 0.347 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.009AsnAla: 3.009 ± 0.055	0.252AsnCys: 0.252 ± 0.014	1.606AsnAsp: 1.606 ± 0.051	1.537AsnGlu: 1.537 ± 0.035	0.815AsnPhe: 0.815 ± 0.028	2.103AsnGly: 2.103 ± 0.067	0.571AsnHis: 0.571 ± 0.022	1.233AsnIle: 1.233 ± 0.033	0.635AsnLys: 0.635 ± 0.026	2.788AsnLeu: 2.788 ± 0.058	0.587AsnMet: 0.587 ± 0.02	0.693AsnAsn: 0.693 ± 0.029	1.674AsnPro: 1.674 ± 0.041	0.933AsnGln: 0.933 ± 0.03	1.889AsnArg: 1.889 ± 0.049	1.192AsnSer: 1.192 ± 0.037	1.271AsnThr: 1.271 ± 0.032	1.809AsnVal: 1.809 ± 0.044	0.345AsnTrp: 0.345 ± 0.016	0.678AsnTyr: 0.678 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.027ProAla: 5.027 ± 0.07	0.395ProCys: 0.395 ± 0.02	3.211ProAsp: 3.211 ± 0.053	3.959ProGlu: 3.959 ± 0.055	1.762ProPhe: 1.762 ± 0.038	4.527ProGly: 4.527 ± 0.064	1.091ProHis: 1.091 ± 0.034	2.016ProIle: 2.016 ± 0.043	1.102ProLys: 1.102 ± 0.033	5.533ProLeu: 5.533 ± 0.074	1.186ProMet: 1.186 ± 0.034	1.107ProAsn: 1.107 ± 0.032	2.225ProPro: 2.225 ± 0.053	1.715ProGln: 1.715 ± 0.036	3.387ProArg: 3.387 ± 0.065	2.69ProSer: 2.69 ± 0.048	2.157ProThr: 2.157 ± 0.04	3.77ProVal: 3.77 ± 0.06	0.834ProTrp: 0.834 ± 0.03	1.14ProTyr: 1.14 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	5.244GlnAla: 5.244 ± 0.082	0.292GlnCys: 0.292 ± 0.016	1.808GlnAsp: 1.808 ± 0.033	2.356GlnGlu: 2.356 ± 0.051	0.988GlnPhe: 0.988 ± 0.03	3.453GlnGly: 3.453 ± 0.066	0.958GlnHis: 0.958 ± 0.029	1.487GlnIle: 1.487 ± 0.029	0.962GlnLys: 0.962 ± 0.03	3.898GlnLeu: 3.898 ± 0.062	0.839GlnMet: 0.839 ± 0.031	0.784GlnAsn: 0.784 ± 0.027	1.854GlnPro: 1.854 ± 0.039	1.991GlnGln: 1.991 ± 0.054	3.559GlnArg: 3.559 ± 0.063	1.735GlnSer: 1.735 ± 0.047	1.59GlnThr: 1.59 ± 0.04	2.91GlnVal: 2.91 ± 0.05	0.614GlnTrp: 0.614 ± 0.022	0.718GlnTyr: 0.718 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	6.531ArgAla: 6.531 ± 0.099	0.636ArgCys: 0.636 ± 0.024	4.313ArgAsp: 4.313 ± 0.068	5.401ArgGlu: 5.401 ± 0.092	2.977ArgPhe: 2.977 ± 0.045	4.793ArgGly: 4.793 ± 0.061	2.467ArgHis: 2.467 ± 0.055	3.611ArgIle: 3.611 ± 0.062	1.893ArgLys: 1.893 ± 0.045	10.291ArgLeu: 10.291 ± 0.128	1.723ArgMet: 1.723 ± 0.046	1.721ArgAsn: 1.721 ± 0.039	3.123ArgPro: 3.123 ± 0.055	3.554ArgGln: 3.554 ± 0.067	6.517ArgArg: 6.517 ± 0.108	3.398ArgSer: 3.398 ± 0.059	2.912ArgThr: 2.912 ± 0.061	5.094ArgVal: 5.094 ± 0.073	1.198ArgTrp: 1.198 ± 0.038	2.172ArgTyr: 2.172 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	5.353SerAla: 5.353 ± 0.069	0.462SerCys: 0.462 ± 0.021	3.043SerAsp: 3.043 ± 0.058	3.179SerGlu: 3.179 ± 0.053	1.946SerPhe: 1.946 ± 0.048	5.056SerGly: 5.056 ± 0.08	1.274SerHis: 1.274 ± 0.035	2.444SerIle: 2.444 ± 0.047	1.274SerLys: 1.274 ± 0.039	6.498SerLeu: 6.498 ± 0.085	1.425SerMet: 1.425 ± 0.037	1.364SerAsn: 1.364 ± 0.042	2.804SerPro: 2.804 ± 0.045	2.026SerGln: 2.026 ± 0.041	4.328SerArg: 4.328 ± 0.065	3.131SerSer: 3.131 ± 0.054	2.649SerThr: 2.649 ± 0.052	3.654SerVal: 3.654 ± 0.064	0.753SerTrp: 0.753 ± 0.026	1.254SerTyr: 1.254 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	4.944ThrAla: 4.944 ± 0.077	0.441ThrCys: 0.441 ± 0.021	2.448ThrAsp: 2.448 ± 0.056	2.424ThrGlu: 2.424 ± 0.047	1.83ThrPhe: 1.83 ± 0.041	4.252ThrGly: 4.252 ± 0.063	1.19ThrHis: 1.19 ± 0.034	2.157ThrIle: 2.157 ± 0.051	0.952ThrLys: 0.952 ± 0.033	7.52ThrLeu: 7.52 ± 0.096	1.012ThrMet: 1.012 ± 0.03	1.137ThrAsn: 1.137 ± 0.03	3.391ThrPro: 3.391 ± 0.053	1.777ThrGln: 1.777 ± 0.041	3.642ThrArg: 3.642 ± 0.061	2.686ThrSer: 2.686 ± 0.043	2.722ThrThr: 2.722 ± 0.056	3.367ThrVal: 3.367 ± 0.055	0.699ThrTrp: 0.699 ± 0.026	1.107ThrTyr: 1.107 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.913ValAla: 7.913 ± 0.102	0.649ValCys: 0.649 ± 0.022	4.286ValAsp: 4.286 ± 0.064	4.862ValGlu: 4.862 ± 0.08	2.542ValPhe: 2.542 ± 0.049	5.244ValGly: 5.244 ± 0.073	1.493ValHis: 1.493 ± 0.036	4.005ValIle: 4.005 ± 0.063	1.984ValLys: 1.984 ± 0.048	7.733ValLeu: 7.733 ± 0.086	1.971ValMet: 1.971 ± 0.04	1.959ValAsn: 1.959 ± 0.043	3.384ValPro: 3.384 ± 0.048	2.186ValGln: 2.186 ± 0.045	4.383ValArg: 4.383 ± 0.067	4.024ValSer: 4.024 ± 0.072	4.08ValThr: 4.08 ± 0.071	5.67ValVal: 5.67 ± 0.083	0.863ValTrp: 0.863 ± 0.035	1.583ValTyr: 1.583 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.197TrpAla: 1.197 ± 0.035	0.176TrpCys: 0.176 ± 0.012	0.572TrpAsp: 0.572 ± 0.023	0.692TrpGlu: 0.692 ± 0.023	0.551TrpPhe: 0.551 ± 0.022	1.001TrpGly: 1.001 ± 0.031	0.437TrpHis: 0.437 ± 0.017	0.663TrpIle: 0.663 ± 0.026	0.377TrpLys: 0.377 ± 0.018	2.509TrpLeu: 2.509 ± 0.061	0.412TrpMet: 0.412 ± 0.017	0.387TrpAsn: 0.387 ± 0.018	0.735TrpPro: 0.735 ± 0.028	0.945TrpGln: 0.945 ± 0.031	1.276TrpArg: 1.276 ± 0.036	0.821TrpSer: 0.821 ± 0.027	0.628TrpThr: 0.628 ± 0.024	0.968TrpVal: 0.968 ± 0.03	0.329TrpTrp: 0.329 ± 0.018	0.338TrpTyr: 0.338 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.406TyrAla: 2.406 ± 0.054	0.263TyrCys: 0.263 ± 0.015	1.358TyrAsp: 1.358 ± 0.043	1.192TyrGlu: 1.192 ± 0.033	0.956TyrPhe: 0.956 ± 0.028	2.068TyrGly: 2.068 ± 0.045	0.648TyrHis: 0.648 ± 0.023	0.93TyrIle: 0.93 ± 0.029	0.546TyrLys: 0.546 ± 0.021	2.899TyrLeu: 2.899 ± 0.044	0.506TyrMet: 0.506 ± 0.02	0.594TyrAsn: 0.594 ± 0.025	1.265TyrPro: 1.265 ± 0.034	1.037TyrGln: 1.037 ± 0.033	2.308TyrArg: 2.308 ± 0.043	1.296TyrSer: 1.296 ± 0.034	1.176TyrThr: 1.176 ± 0.034	1.546TyrVal: 1.546 ± 0.035	0.402TyrTrp: 0.402 ± 0.019	0.691TyrTyr: 0.691 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3660 proteins (1184749 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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