Amino acid dipepetide frequency for Wuhan insect virus 21

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.925AlaAla: 8.925 ± 1.687
1.275AlaCys: 1.275 ± 0.576
4.675AlaAsp: 4.675 ± 1.031
2.975AlaGlu: 2.975 ± 0.496
3.825AlaPhe: 3.825 ± 0.994
4.675AlaGly: 4.675 ± 0.451
2.55AlaHis: 2.55 ± 0.737
3.4AlaIle: 3.4 ± 1.559
3.4AlaLys: 3.4 ± 1.449
9.35AlaLeu: 9.35 ± 2.863
1.7AlaMet: 1.7 ± 1.109
4.25AlaAsn: 4.25 ± 1.3
2.55AlaPro: 2.55 ± 0.477
3.825AlaGln: 3.825 ± 0.944
7.225AlaArg: 7.225 ± 1.773
5.525AlaSer: 5.525 ± 1.888
5.95AlaThr: 5.95 ± 1.919
6.8AlaVal: 6.8 ± 1.767
1.275AlaTrp: 1.275 ± 0.493
1.275AlaTyr: 1.275 ± 0.642
0.0AlaXaa: 0.0 ± 0.0
Cys
1.7CysAla: 1.7 ± 0.783
0.85CysCys: 0.85 ± 0.748
1.7CysAsp: 1.7 ± 0.493
0.85CysGlu: 0.85 ± 0.338
0.425CysPhe: 0.425 ± 0.558
1.7CysGly: 1.7 ± 0.493
0.425CysHis: 0.425 ± 0.374
1.7CysIle: 1.7 ± 0.991
0.85CysLys: 0.85 ± 0.591
2.125CysLeu: 2.125 ± 1.123
0.425CysMet: 0.425 ± 0.374
0.425CysAsn: 0.425 ± 0.295
1.275CysPro: 1.275 ± 0.513
0.85CysGln: 0.85 ± 0.433
2.55CysArg: 2.55 ± 1.297
2.125CysSer: 2.125 ± 1.123
1.7CysThr: 1.7 ± 0.501
1.275CysVal: 1.275 ± 0.886
0.0CysTrp: 0.0 ± 0.0
1.275CysTyr: 1.275 ± 0.536
0.0CysXaa: 0.0 ± 0.0
Asp
7.225AspAla: 7.225 ± 1.25
2.125AspCys: 2.125 ± 0.405
1.7AspAsp: 1.7 ± 0.252
1.7AspGlu: 1.7 ± 0.745
2.55AspPhe: 2.55 ± 0.533
5.1AspGly: 5.1 ± 0.78
2.55AspHis: 2.55 ± 1.127
3.4AspIle: 3.4 ± 0.504
1.7AspLys: 1.7 ± 0.676
2.975AspLeu: 2.975 ± 0.34
2.55AspMet: 2.55 ± 0.377
0.85AspAsn: 0.85 ± 0.338
3.825AspPro: 3.825 ± 0.648
2.125AspGln: 2.125 ± 0.513
3.825AspArg: 3.825 ± 1.482
2.975AspSer: 2.975 ± 0.899
3.4AspThr: 3.4 ± 1.237
3.4AspVal: 3.4 ± 0.816
1.275AspTrp: 1.275 ± 0.718
2.975AspTyr: 2.975 ± 0.34
0.0AspXaa: 0.0 ± 0.0
Glu
1.7GluAla: 1.7 ± 0.745
0.0GluCys: 0.0 ± 0.0
2.975GluAsp: 2.975 ± 1.243
2.125GluGlu: 2.125 ± 1.021
2.55GluPhe: 2.55 ± 0.869
5.525GluGly: 5.525 ± 1.729
2.975GluHis: 2.975 ± 0.69
2.55GluIle: 2.55 ± 1.026
1.275GluLys: 1.275 ± 0.724
2.975GluLeu: 2.975 ± 1.229
0.85GluMet: 0.85 ± 0.75
2.55GluAsn: 2.55 ± 0.799
1.7GluPro: 1.7 ± 0.646
1.275GluGln: 1.275 ± 0.195
3.4GluArg: 3.4 ± 0.948
2.125GluSer: 2.125 ± 1.369
2.975GluThr: 2.975 ± 0.649
2.125GluVal: 2.125 ± 0.854
0.85GluTrp: 0.85 ± 0.433
2.125GluTyr: 2.125 ± 1.273
0.0GluXaa: 0.0 ± 0.0
Phe
1.275PheAla: 1.275 ± 0.536
1.275PheCys: 1.275 ± 0.195
2.125PheAsp: 2.125 ± 0.602
3.825PheGlu: 3.825 ± 0.561
0.0PhePhe: 0.0 ± 0.0
0.425PheGly: 0.425 ± 0.374
2.125PheHis: 2.125 ± 0.381
1.7PheIle: 1.7 ± 0.493
1.7PheLys: 1.7 ± 0.493
3.4PheLeu: 3.4 ± 2.071
0.85PheMet: 0.85 ± 0.433
2.55PheAsn: 2.55 ± 1.16
1.275PhePro: 1.275 ± 0.493
1.275PheGln: 1.275 ± 0.493
1.7PheArg: 1.7 ± 0.766
1.275PheSer: 1.275 ± 0.576
2.55PheThr: 2.55 ± 0.869
3.4PheVal: 3.4 ± 0.929
0.0PheTrp: 0.0 ± 0.0
0.425PheTyr: 0.425 ± 0.295
0.0PheXaa: 0.0 ± 0.0
Gly
5.95GlyAla: 5.95 ± 1.602
2.125GlyCys: 2.125 ± 1.083
3.825GlyAsp: 3.825 ± 0.585
2.55GlyGlu: 2.55 ± 1.467
1.7GlyPhe: 1.7 ± 0.493
2.125GlyGly: 2.125 ± 0.779
2.125GlyHis: 2.125 ± 0.964
2.55GlyIle: 2.55 ± 0.471
4.675GlyLys: 4.675 ± 1.803
5.525GlyLeu: 5.525 ± 0.243
0.85GlyMet: 0.85 ± 0.61
2.125GlyAsn: 2.125 ± 1.021
4.675GlyPro: 4.675 ± 1.302
2.55GlyGln: 2.55 ± 0.922
4.675GlyArg: 4.675 ± 0.7
5.95GlySer: 5.95 ± 1.749
5.95GlyThr: 5.95 ± 1.025
3.4GlyVal: 3.4 ± 0.784
0.425GlyTrp: 0.425 ± 0.295
0.425GlyTyr: 0.425 ± 0.374
0.0GlyXaa: 0.0 ± 0.0
His
2.975HisAla: 2.975 ± 1.243
1.275HisCys: 1.275 ± 0.195
1.7HisAsp: 1.7 ± 0.676
1.7HisGlu: 1.7 ± 0.493
0.425HisPhe: 0.425 ± 0.295
2.55HisGly: 2.55 ± 1.014
2.125HisHis: 2.125 ± 0.817
1.7HisIle: 1.7 ± 0.642
1.275HisLys: 1.275 ± 0.513
1.275HisLeu: 1.275 ± 0.493
0.425HisMet: 0.425 ± 0.374
0.85HisAsn: 0.85 ± 0.323
2.975HisPro: 2.975 ± 0.662
2.125HisGln: 2.125 ± 0.602
4.25HisArg: 4.25 ± 0.717
4.25HisSer: 4.25 ± 1.22
3.825HisThr: 3.825 ± 0.899
2.125HisVal: 2.125 ± 0.817
0.0HisTrp: 0.0 ± 0.0
0.85HisTyr: 0.85 ± 0.591
0.0HisXaa: 0.0 ± 0.0
Ile
6.375IleAla: 6.375 ± 1.8
2.55IleCys: 2.55 ± 0.477
2.55IleAsp: 2.55 ± 1.773
2.55IleGlu: 2.55 ± 1.436
0.85IlePhe: 0.85 ± 0.323
2.55IleGly: 2.55 ± 0.712
1.275IleHis: 1.275 ± 0.493
2.975IleIle: 2.975 ± 1.651
2.125IleLys: 2.125 ± 1.732
2.55IleLeu: 2.55 ± 0.985
1.7IleMet: 1.7 ± 0.442
0.85IleAsn: 0.85 ± 0.591
3.825IlePro: 3.825 ± 0.648
0.425IleGln: 0.425 ± 0.374
5.525IleArg: 5.525 ± 1.2
5.95IleSer: 5.95 ± 1.16
2.125IleThr: 2.125 ± 1.125
1.275IleVal: 1.275 ± 0.886
0.85IleTrp: 0.85 ± 0.652
1.7IleTyr: 1.7 ± 0.642
0.0IleXaa: 0.0 ± 0.0
Lys
1.275LysAla: 1.275 ± 0.718
0.85LysCys: 0.85 ± 0.323
3.4LysAsp: 3.4 ± 1.686
1.275LysGlu: 1.275 ± 0.576
0.425LysPhe: 0.425 ± 0.375
0.85LysGly: 0.85 ± 0.433
2.55LysHis: 2.55 ± 1.026
1.7LysIle: 1.7 ± 0.646
2.125LysLys: 2.125 ± 0.776
3.825LysLeu: 3.825 ± 1.478
0.425LysMet: 0.425 ± 0.558
0.425LysAsn: 0.425 ± 0.375
0.85LysPro: 0.85 ± 0.338
1.275LysGln: 1.275 ± 0.576
3.4LysArg: 3.4 ± 0.767
2.55LysSer: 2.55 ± 1.014
3.4LysThr: 3.4 ± 0.604
2.975LysVal: 2.975 ± 0.942
0.425LysTrp: 0.425 ± 0.374
0.425LysTyr: 0.425 ± 0.375
0.0LysXaa: 0.0 ± 0.0
Leu
8.925LeuAla: 8.925 ± 0.639
0.85LeuCys: 0.85 ± 0.748
2.55LeuAsp: 2.55 ± 1.433
3.4LeuGlu: 3.4 ± 0.601
2.125LeuPhe: 2.125 ± 0.619
3.825LeuGly: 3.825 ± 1.353
3.4LeuHis: 3.4 ± 1.382
2.975LeuIle: 2.975 ± 0.955
3.4LeuLys: 3.4 ± 0.663
8.925LeuLeu: 8.925 ± 3.606
0.85LeuMet: 0.85 ± 0.323
1.7LeuAsn: 1.7 ± 0.865
4.675LeuPro: 4.675 ± 1.682
2.975LeuGln: 2.975 ± 1.218
7.225LeuArg: 7.225 ± 1.513
6.8LeuSer: 6.8 ± 1.217
7.65LeuThr: 7.65 ± 1.849
5.525LeuVal: 5.525 ± 1.393
0.85LeuTrp: 0.85 ± 0.323
1.275LeuTyr: 1.275 ± 0.718
0.0LeuXaa: 0.0 ± 0.0
Met
0.85MetAla: 0.85 ± 0.626
0.85MetCys: 0.85 ± 0.323
0.425MetAsp: 0.425 ± 0.375
0.85MetGlu: 0.85 ± 0.433
1.275MetPhe: 1.275 ± 0.195
2.55MetGly: 2.55 ± 0.85
0.425MetHis: 0.425 ± 0.295
2.125MetIle: 2.125 ± 1.42
0.0MetLys: 0.0 ± 0.0
2.125MetLeu: 2.125 ± 0.619
0.0MetMet: 0.0 ± 0.0
0.425MetAsn: 0.425 ± 0.375
2.55MetPro: 2.55 ± 1.029
0.0MetGln: 0.0 ± 0.0
1.7MetArg: 1.7 ± 0.493
1.275MetSer: 1.275 ± 0.195
1.275MetThr: 1.275 ± 0.868
0.0MetVal: 0.0 ± 0.0
0.85MetTrp: 0.85 ± 0.748
0.425MetTyr: 0.425 ± 0.374
0.0MetXaa: 0.0 ± 0.0
Asn
1.7AsnAla: 1.7 ± 0.493
0.425AsnCys: 0.425 ± 0.374
2.55AsnAsp: 2.55 ± 1.014
2.125AsnGlu: 2.125 ± 1.021
1.7AsnPhe: 1.7 ± 0.991
1.7AsnGly: 1.7 ± 0.501
1.275AsnHis: 1.275 ± 0.649
2.55AsnIle: 2.55 ± 0.969
1.275AsnLys: 1.275 ± 0.635
1.7AsnLeu: 1.7 ± 0.493
0.85AsnMet: 0.85 ± 0.75
0.85AsnAsn: 0.85 ± 0.591
1.7AsnPro: 1.7 ± 0.783
0.0AsnGln: 0.0 ± 0.0
2.125AsnArg: 2.125 ± 0.39
0.425AsnSer: 0.425 ± 0.295
1.7AsnThr: 1.7 ± 0.501
2.975AsnVal: 2.975 ± 0.649
0.85AsnTrp: 0.85 ± 0.323
1.275AsnTyr: 1.275 ± 0.635
0.0AsnXaa: 0.0 ± 0.0
Pro
6.375ProAla: 6.375 ± 2.051
1.7ProCys: 1.7 ± 1.061
5.1ProAsp: 5.1 ± 0.941
4.25ProGlu: 4.25 ± 0.709
2.55ProPhe: 2.55 ± 1.232
4.675ProGly: 4.675 ± 1.831
2.125ProHis: 2.125 ± 0.863
2.125ProIle: 2.125 ± 1.083
2.975ProLys: 2.975 ± 1.086
2.975ProLeu: 2.975 ± 1.464
1.7ProMet: 1.7 ± 0.576
1.275ProAsn: 1.275 ± 0.493
4.675ProPro: 4.675 ± 1.129
1.7ProGln: 1.7 ± 0.646
6.8ProArg: 6.8 ± 2.059
3.4ProSer: 3.4 ± 1.382
4.675ProThr: 4.675 ± 0.725
2.975ProVal: 2.975 ± 1.264
0.85ProTrp: 0.85 ± 0.574
1.7ProTyr: 1.7 ± 0.501
0.0ProXaa: 0.0 ± 0.0
Gln
2.975GlnAla: 2.975 ± 1.193
0.425GlnCys: 0.425 ± 0.295
2.55GlnAsp: 2.55 ± 1.026
1.7GlnGlu: 1.7 ± 0.676
1.7GlnPhe: 1.7 ± 0.724
2.55GlnGly: 2.55 ± 0.471
0.425GlnHis: 0.425 ± 0.375
1.7GlnIle: 1.7 ± 0.745
0.425GlnLys: 0.425 ± 0.375
2.975GlnLeu: 2.975 ± 0.394
0.425GlnMet: 0.425 ± 0.375
0.425GlnAsn: 0.425 ± 0.375
2.125GlnPro: 2.125 ± 1.369
1.7GlnGln: 1.7 ± 0.766
2.55GlnArg: 2.55 ± 0.869
2.125GlnSer: 2.125 ± 0.863
2.125GlnThr: 2.125 ± 0.776
1.7GlnVal: 1.7 ± 0.745
0.0GlnTrp: 0.0 ± 0.0
0.85GlnTyr: 0.85 ± 0.75
0.0GlnXaa: 0.0 ± 0.0
Arg
8.925ArgAla: 8.925 ± 1.805
0.85ArgCys: 0.85 ± 0.323
6.8ArgAsp: 6.8 ± 0.824
4.675ArgGlu: 4.675 ± 0.911
5.1ArgPhe: 5.1 ± 0.972
4.25ArgGly: 4.25 ± 1.595
3.4ArgHis: 3.4 ± 1.322
2.125ArgIle: 2.125 ± 0.513
1.275ArgLys: 1.275 ± 0.635
5.1ArgLeu: 5.1 ± 1.535
0.85ArgMet: 0.85 ± 0.338
2.55ArgAsn: 2.55 ± 0.39
8.5ArgPro: 8.5 ± 0.586
2.975ArgGln: 2.975 ± 0.93
8.925ArgArg: 8.925 ± 2.347
5.95ArgSer: 5.95 ± 1.148
5.1ArgThr: 5.1 ± 1.199
4.675ArgVal: 4.675 ± 1.311
0.425ArgTrp: 0.425 ± 0.375
2.975ArgTyr: 2.975 ± 1.086
0.0ArgXaa: 0.0 ± 0.0
Ser
4.675SerAla: 4.675 ± 1.072
1.7SerCys: 1.7 ± 0.493
3.825SerAsp: 3.825 ± 0.754
2.55SerGlu: 2.55 ± 0.799
0.85SerPhe: 0.85 ± 0.338
8.5SerGly: 8.5 ± 1.672
2.55SerHis: 2.55 ± 0.471
5.1SerIle: 5.1 ± 0.936
0.425SerLys: 0.425 ± 0.295
3.4SerLeu: 3.4 ± 0.784
1.7SerMet: 1.7 ± 0.676
0.85SerAsn: 0.85 ± 0.748
4.25SerPro: 4.25 ± 1.205
2.55SerGln: 2.55 ± 0.985
7.225SerArg: 7.225 ± 1.111
7.225SerSer: 7.225 ± 0.869
5.1SerThr: 5.1 ± 1.009
2.975SerVal: 2.975 ± 0.34
2.55SerTrp: 2.55 ± 0.39
4.675SerTyr: 4.675 ± 0.686
0.0SerXaa: 0.0 ± 0.0
Thr
5.95ThrAla: 5.95 ± 1.049
1.7ThrCys: 1.7 ± 1.496
4.675ThrAsp: 4.675 ± 0.686
2.55ThrGlu: 2.55 ± 0.799
2.55ThrPhe: 2.55 ± 0.712
4.25ThrGly: 4.25 ± 0.809
2.55ThrHis: 2.55 ± 0.471
3.825ThrIle: 3.825 ± 1.249
0.85ThrLys: 0.85 ± 0.591
7.225ThrLeu: 7.225 ± 3.329
1.7ThrMet: 1.7 ± 0.825
2.125ThrAsn: 2.125 ± 1.416
4.25ThrPro: 4.25 ± 0.682
0.85ThrGln: 0.85 ± 0.433
6.375ThrArg: 6.375 ± 2.099
5.525ThrSer: 5.525 ± 1.462
6.375ThrThr: 6.375 ± 2.82
6.8ThrVal: 6.8 ± 1.207
0.85ThrTrp: 0.85 ± 0.75
2.975ThrTyr: 2.975 ± 0.496
0.0ThrXaa: 0.0 ± 0.0
Val
5.1ValAla: 5.1 ± 0.826
2.975ValCys: 2.975 ± 0.687
2.125ValAsp: 2.125 ± 0.39
1.275ValGlu: 1.275 ± 0.635
0.85ValPhe: 0.85 ± 0.433
3.4ValGly: 3.4 ± 1.729
2.125ValHis: 2.125 ± 0.513
5.1ValIle: 5.1 ± 0.954
3.825ValLys: 3.825 ± 0.85
7.65ValLeu: 7.65 ± 1.12
0.85ValMet: 0.85 ± 0.652
2.125ValAsn: 2.125 ± 0.602
6.375ValPro: 6.375 ± 1.18
2.125ValGln: 2.125 ± 0.863
3.825ValArg: 3.825 ± 0.993
4.25ValSer: 4.25 ± 0.795
4.675ValThr: 4.675 ± 1.734
5.1ValVal: 5.1 ± 0.638
0.85ValTrp: 0.85 ± 0.338
0.85ValTyr: 0.85 ± 0.338
0.0ValXaa: 0.0 ± 0.0
Trp
0.425TrpAla: 0.425 ± 0.558
0.0TrpCys: 0.0 ± 0.0
0.85TrpAsp: 0.85 ± 0.338
0.425TrpGlu: 0.425 ± 0.375
0.0TrpPhe: 0.0 ± 0.0
0.425TrpGly: 0.425 ± 0.374
0.425TrpHis: 0.425 ± 0.374
0.0TrpIle: 0.0 ± 0.0
0.425TrpLys: 0.425 ± 0.375
1.275TrpLeu: 1.275 ± 0.718
0.425TrpMet: 0.425 ± 0.375
0.85TrpAsn: 0.85 ± 0.323
1.275TrpPro: 1.275 ± 0.649
0.0TrpGln: 0.0 ± 0.0
1.275TrpArg: 1.275 ± 0.536
0.425TrpSer: 0.425 ± 0.295
1.7TrpThr: 1.7 ± 0.252
2.55TrpVal: 2.55 ± 0.712
0.425TrpTrp: 0.425 ± 0.295
0.425TrpTyr: 0.425 ± 0.374
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.125TyrAla: 2.125 ± 0.39
0.425TyrCys: 0.425 ± 0.374
2.55TyrAsp: 2.55 ± 0.501
1.275TyrGlu: 1.275 ± 0.635
1.7TyrPhe: 1.7 ± 0.646
2.55TyrGly: 2.55 ± 0.477
1.275TyrHis: 1.275 ± 0.195
1.275TyrIle: 1.275 ± 0.536
0.425TyrLys: 0.425 ± 0.374
2.55TyrLeu: 2.55 ± 0.929
0.425TyrMet: 0.425 ± 0.295
1.7TyrAsn: 1.7 ± 0.493
1.275TyrPro: 1.275 ± 1.125
0.85TyrGln: 0.85 ± 0.748
0.85TyrArg: 0.85 ± 0.591
2.55TyrSer: 2.55 ± 0.922
1.7TyrThr: 1.7 ± 0.252
3.4TyrVal: 3.4 ± 1.035
0.0TyrTrp: 0.0 ± 0.0
0.85TyrTyr: 0.85 ± 0.338
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski