Amino acid dipepetide frequency for Mosquito VEM virus SDRBAJ

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.669AlaAla: 9.669 ± 3.5
0.0AlaCys: 0.0 ± 0.0
4.144AlaAsp: 4.144 ± 1.137
1.381AlaGlu: 1.381 ± 1.813
1.381AlaPhe: 1.381 ± 0.765
6.906AlaGly: 6.906 ± 2.104
2.762AlaHis: 2.762 ± 1.218
6.906AlaIle: 6.906 ± 2.229
2.762AlaLys: 2.762 ± 1.531
8.287AlaLeu: 8.287 ± 2.275
1.381AlaMet: 1.381 ± 1.813
2.762AlaAsn: 2.762 ± 1.548
2.762AlaPro: 2.762 ± 1.218
1.381AlaGln: 1.381 ± 1.813
5.525AlaArg: 5.525 ± 0.825
4.144AlaSer: 4.144 ± 2.296
6.906AlaThr: 6.906 ± 0.432
4.144AlaVal: 4.144 ± 2.842
1.381AlaTrp: 1.381 ± 0.765
5.525AlaTyr: 5.525 ± 1.508
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.381CysGly: 1.381 ± 0.765
4.144CysHis: 4.144 ± 2.842
1.381CysIle: 1.381 ± 0.765
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.381CysMet: 1.381 ± 1.238
1.381CysAsn: 1.381 ± 0.765
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.381CysSer: 1.381 ± 1.687
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
2.762AspAsp: 2.762 ± 1.218
2.762AspGlu: 2.762 ± 2.277
2.762AspPhe: 2.762 ± 1.548
2.762AspGly: 2.762 ± 2.277
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
2.762AspLys: 2.762 ± 1.531
2.762AspLeu: 2.762 ± 1.218
1.381AspMet: 1.381 ± 1.813
4.144AspAsn: 4.144 ± 1.637
4.144AspPro: 4.144 ± 3.284
0.0AspGln: 0.0 ± 0.0
1.381AspArg: 1.381 ± 0.765
6.906AspSer: 6.906 ± 2.6
4.144AspThr: 4.144 ± 1.137
2.762AspVal: 2.762 ± 1.218
1.381AspTrp: 1.381 ± 1.813
1.381AspTyr: 1.381 ± 0.765
0.0AspXaa: 0.0 ± 0.0
Glu
1.381GluAla: 1.381 ± 1.687
0.0GluCys: 0.0 ± 0.0
1.381GluAsp: 1.381 ± 1.813
2.762GluGlu: 2.762 ± 2.277
0.0GluPhe: 0.0 ± 0.0
5.525GluGly: 5.525 ± 2.436
4.144GluHis: 4.144 ± 2.842
5.525GluIle: 5.525 ± 0.825
2.762GluLys: 2.762 ± 3.374
0.0GluLeu: 0.0 ± 0.0
0.0GluMet: 0.0 ± 0.0
1.381GluAsn: 1.381 ± 0.765
1.381GluPro: 1.381 ± 1.813
2.762GluGln: 2.762 ± 3.626
2.762GluArg: 2.762 ± 3.374
5.525GluSer: 5.525 ± 0.825
1.381GluThr: 1.381 ± 0.765
5.525GluVal: 5.525 ± 3.097
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.381PheAla: 1.381 ± 1.687
1.381PheCys: 1.381 ± 1.687
4.144PheAsp: 4.144 ± 2.296
1.381PheGlu: 1.381 ± 1.813
1.381PhePhe: 1.381 ± 0.765
2.762PheGly: 2.762 ± 1.531
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.381PheLys: 1.381 ± 1.813
5.525PheLeu: 5.525 ± 0.825
0.0PheMet: 0.0 ± 0.0
1.381PheAsn: 1.381 ± 1.813
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
5.525PheArg: 5.525 ± 3.062
5.525PheSer: 5.525 ± 3.062
6.906PheThr: 6.906 ± 6.192
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
13.812GlyAla: 13.812 ± 4.209
2.762GlyCys: 2.762 ± 1.218
1.381GlyAsp: 1.381 ± 1.687
4.144GlyGlu: 4.144 ± 2.296
1.381GlyPhe: 1.381 ± 0.765
5.525GlyGly: 5.525 ± 3.062
1.381GlyHis: 1.381 ± 0.765
4.144GlyIle: 4.144 ± 1.532
5.525GlyLys: 5.525 ± 1.508
2.762GlyLeu: 2.762 ± 1.218
0.0GlyMet: 0.0 ± 0.0
2.762GlyAsn: 2.762 ± 1.218
8.287GlyPro: 8.287 ± 0.929
2.762GlyGln: 2.762 ± 1.531
6.906GlyArg: 6.906 ± 3.827
8.287GlySer: 8.287 ± 1.391
6.906GlyThr: 6.906 ± 2.092
4.144GlyVal: 4.144 ± 2.296
0.0GlyTrp: 0.0 ± 0.0
1.381GlyTyr: 1.381 ± 0.765
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.381HisCys: 1.381 ± 1.687
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
2.762HisPhe: 2.762 ± 2.277
1.381HisGly: 1.381 ± 0.765
0.0HisHis: 0.0 ± 0.0
4.144HisIle: 4.144 ± 1.137
2.762HisLys: 2.762 ± 1.218
2.762HisLeu: 2.762 ± 1.548
0.0HisMet: 0.0 ± 0.0
1.381HisAsn: 1.381 ± 0.765
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.762HisArg: 2.762 ± 1.218
1.381HisSer: 1.381 ± 0.765
1.381HisThr: 1.381 ± 0.765
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
4.144HisTyr: 4.144 ± 1.137
0.0HisXaa: 0.0 ± 0.0
Ile
8.287IleAla: 8.287 ± 3.065
0.0IleCys: 0.0 ± 0.0
2.762IleAsp: 2.762 ± 1.218
4.144IleGlu: 4.144 ± 5.061
2.762IlePhe: 2.762 ± 1.531
4.144IleGly: 4.144 ± 2.296
4.144IleHis: 4.144 ± 1.637
2.762IleIle: 2.762 ± 1.531
2.762IleLys: 2.762 ± 1.218
2.762IleLeu: 2.762 ± 1.531
0.0IleMet: 0.0 ± 0.0
5.525IleAsn: 5.525 ± 2.033
6.906IlePro: 6.906 ± 3.827
2.762IleGln: 2.762 ± 1.531
2.762IleArg: 2.762 ± 1.531
2.762IleSer: 2.762 ± 1.548
0.0IleThr: 0.0 ± 0.0
2.762IleVal: 2.762 ± 1.218
2.762IleTrp: 2.762 ± 1.531
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.144LysAla: 4.144 ± 1.532
1.381LysCys: 1.381 ± 0.765
2.762LysAsp: 2.762 ± 1.218
2.762LysGlu: 2.762 ± 3.374
1.381LysPhe: 1.381 ± 0.765
4.144LysGly: 4.144 ± 2.842
1.381LysHis: 1.381 ± 1.813
2.762LysIle: 2.762 ± 1.531
4.144LysLys: 4.144 ± 1.137
1.381LysLeu: 1.381 ± 0.765
1.381LysMet: 1.381 ± 0.733
0.0LysAsn: 0.0 ± 0.0
2.762LysPro: 2.762 ± 1.531
2.762LysGln: 2.762 ± 2.277
1.381LysArg: 1.381 ± 0.765
8.287LysSer: 8.287 ± 3.065
0.0LysThr: 0.0 ± 0.0
1.381LysVal: 1.381 ± 0.765
1.381LysTrp: 1.381 ± 0.765
5.525LysTyr: 5.525 ± 4.512
0.0LysXaa: 0.0 ± 0.0
Leu
6.906LeuAla: 6.906 ± 2.229
0.0LeuCys: 0.0 ± 0.0
1.381LeuAsp: 1.381 ± 0.765
2.762LeuGlu: 2.762 ± 2.277
1.381LeuPhe: 1.381 ± 0.765
1.381LeuGly: 1.381 ± 0.765
1.381LeuHis: 1.381 ± 0.765
2.762LeuIle: 2.762 ± 1.531
6.906LeuLys: 6.906 ± 2.229
5.525LeuLeu: 5.525 ± 2.436
0.0LeuMet: 0.0 ± 0.0
4.144LeuAsn: 4.144 ± 2.296
1.381LeuPro: 1.381 ± 1.687
0.0LeuGln: 0.0 ± 0.0
2.762LeuArg: 2.762 ± 1.531
6.906LeuSer: 6.906 ± 3.806
2.762LeuThr: 2.762 ± 1.531
5.525LeuVal: 5.525 ± 1.508
5.525LeuTrp: 5.525 ± 3.097
2.762LeuTyr: 2.762 ± 1.531
0.0LeuXaa: 0.0 ± 0.0
Met
2.762MetAla: 2.762 ± 1.531
0.0MetCys: 0.0 ± 0.0
2.762MetAsp: 2.762 ± 1.548
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.381MetIle: 1.381 ± 0.765
4.144MetLys: 4.144 ± 3.755
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.762MetPro: 2.762 ± 1.218
0.0MetGln: 0.0 ± 0.0
1.381MetArg: 1.381 ± 1.813
4.144MetSer: 4.144 ± 3.284
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.381AsnAsp: 1.381 ± 0.765
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
1.381AsnGly: 1.381 ± 0.765
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.762AsnLys: 2.762 ± 1.531
4.144AsnLeu: 4.144 ± 1.137
2.762AsnMet: 2.762 ± 1.531
4.144AsnAsn: 4.144 ± 1.532
5.525AsnPro: 5.525 ± 0.825
1.381AsnGln: 1.381 ± 1.813
2.762AsnArg: 2.762 ± 1.218
4.144AsnSer: 4.144 ± 1.637
4.144AsnThr: 4.144 ± 2.296
1.381AsnVal: 1.381 ± 0.765
4.144AsnTrp: 4.144 ± 1.532
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.381ProAla: 1.381 ± 0.765
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
6.906ProGlu: 6.906 ± 2.578
2.762ProPhe: 2.762 ± 3.626
9.669ProGly: 9.669 ± 0.814
2.762ProHis: 2.762 ± 1.531
5.525ProIle: 5.525 ± 2.033
2.762ProLys: 2.762 ± 2.277
1.381ProLeu: 1.381 ± 0.765
1.381ProMet: 1.381 ± 0.765
0.0ProAsn: 0.0 ± 0.0
4.144ProPro: 4.144 ± 3.575
4.144ProGln: 4.144 ± 1.532
5.525ProArg: 5.525 ± 2.033
5.525ProSer: 5.525 ± 0.825
1.381ProThr: 1.381 ± 1.813
2.762ProVal: 2.762 ± 1.531
1.381ProTrp: 1.381 ± 1.687
1.381ProTyr: 1.381 ± 1.687
0.0ProXaa: 0.0 ± 0.0
Gln
2.762GlnAla: 2.762 ± 1.218
1.381GlnCys: 1.381 ± 0.765
4.144GlnAsp: 4.144 ± 3.284
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
2.762GlnGly: 2.762 ± 1.218
0.0GlnHis: 0.0 ± 0.0
4.144GlnIle: 4.144 ± 1.637
0.0GlnLys: 0.0 ± 0.0
2.762GlnLeu: 2.762 ± 1.218
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
2.762GlnPro: 2.762 ± 2.277
0.0GlnGln: 0.0 ± 0.0
2.762GlnArg: 2.762 ± 1.531
1.381GlnSer: 1.381 ± 1.813
2.762GlnThr: 2.762 ± 1.531
0.0GlnVal: 0.0 ± 0.0
2.762GlnTrp: 2.762 ± 3.626
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.525ArgAla: 5.525 ± 3.062
0.0ArgCys: 0.0 ± 0.0
2.762ArgAsp: 2.762 ± 3.626
4.144ArgGlu: 4.144 ± 1.637
9.669ArgPhe: 9.669 ± 2.559
4.144ArgGly: 4.144 ± 1.137
1.381ArgHis: 1.381 ± 0.765
4.144ArgIle: 4.144 ± 2.842
1.381ArgLys: 1.381 ± 0.765
2.762ArgLeu: 2.762 ± 1.531
0.0ArgMet: 0.0 ± 0.0
1.381ArgAsn: 1.381 ± 1.687
2.762ArgPro: 2.762 ± 1.548
0.0ArgGln: 0.0 ± 0.0
6.906ArgArg: 6.906 ± 2.578
9.669ArgSer: 9.669 ± 3.611
4.144ArgThr: 4.144 ± 1.137
4.144ArgVal: 4.144 ± 1.137
0.0ArgTrp: 0.0 ± 0.0
4.144ArgTyr: 4.144 ± 1.137
0.0ArgXaa: 0.0 ± 0.0
Ser
6.906SerAla: 6.906 ± 0.432
1.381SerCys: 1.381 ± 0.765
2.762SerAsp: 2.762 ± 1.548
4.144SerGlu: 4.144 ± 1.137
2.762SerPhe: 2.762 ± 1.218
12.431SerGly: 12.431 ± 3.151
1.381SerHis: 1.381 ± 1.687
5.525SerIle: 5.525 ± 3.062
2.762SerLys: 2.762 ± 1.218
11.05SerLeu: 11.05 ± 3.669
4.144SerMet: 4.144 ± 3.755
4.144SerAsn: 4.144 ± 2.296
5.525SerPro: 5.525 ± 5.44
5.525SerGln: 5.525 ± 2.033
4.144SerArg: 4.144 ± 1.637
8.287SerSer: 8.287 ± 2.162
9.669SerThr: 9.669 ± 3.94
1.381SerVal: 1.381 ± 1.813
2.762SerTrp: 2.762 ± 2.277
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.144ThrAla: 4.144 ± 1.637
0.0ThrCys: 0.0 ± 0.0
6.906ThrAsp: 6.906 ± 0.432
2.762ThrGlu: 2.762 ± 1.218
1.381ThrPhe: 1.381 ± 0.765
9.669ThrGly: 9.669 ± 5.358
1.381ThrHis: 1.381 ± 0.765
2.762ThrIle: 2.762 ± 1.531
0.0ThrLys: 0.0 ± 0.0
2.762ThrLeu: 2.762 ± 1.218
2.762ThrMet: 2.762 ± 1.531
1.381ThrAsn: 1.381 ± 1.687
1.381ThrPro: 1.381 ± 1.813
0.0ThrGln: 0.0 ± 0.0
4.144ThrArg: 4.144 ± 1.137
4.144ThrSer: 4.144 ± 2.296
4.144ThrThr: 4.144 ± 2.296
4.144ThrVal: 4.144 ± 1.137
2.762ThrTrp: 2.762 ± 1.548
8.287ThrTyr: 8.287 ± 3.71
0.0ThrXaa: 0.0 ± 0.0
Val
4.144ValAla: 4.144 ± 1.137
0.0ValCys: 0.0 ± 0.0
1.381ValAsp: 1.381 ± 0.765
1.381ValGlu: 1.381 ± 1.687
5.525ValPhe: 5.525 ± 2.436
4.144ValGly: 4.144 ± 1.137
0.0ValHis: 0.0 ± 0.0
4.144ValIle: 4.144 ± 1.637
2.762ValLys: 2.762 ± 2.277
1.381ValLeu: 1.381 ± 0.765
0.0ValMet: 0.0 ± 0.0
1.381ValAsn: 1.381 ± 0.765
4.144ValPro: 4.144 ± 1.137
1.381ValGln: 1.381 ± 0.765
2.762ValArg: 2.762 ± 1.218
1.381ValSer: 1.381 ± 0.765
4.144ValThr: 4.144 ± 1.637
6.906ValVal: 6.906 ± 2.229
0.0ValTrp: 0.0 ± 0.0
2.762ValTyr: 2.762 ± 1.531
0.0ValXaa: 0.0 ± 0.0
Trp
6.906TrpAla: 6.906 ± 0.432
0.0TrpCys: 0.0 ± 0.0
1.381TrpAsp: 1.381 ± 1.813
2.762TrpGlu: 2.762 ± 1.548
0.0TrpPhe: 0.0 ± 0.0
1.381TrpGly: 1.381 ± 1.813
0.0TrpHis: 0.0 ± 0.0
1.381TrpIle: 1.381 ± 1.687
0.0TrpLys: 0.0 ± 0.0
1.381TrpLeu: 1.381 ± 0.765
1.381TrpMet: 1.381 ± 3.199
0.0TrpAsn: 0.0 ± 0.0
1.381TrpPro: 1.381 ± 0.765
1.381TrpGln: 1.381 ± 0.765
2.762TrpArg: 2.762 ± 3.626
1.381TrpSer: 1.381 ± 0.765
1.381TrpThr: 1.381 ± 0.765
1.381TrpVal: 1.381 ± 1.687
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.381TyrCys: 1.381 ± 1.687
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.381TyrPhe: 1.381 ± 1.687
2.762TyrGly: 2.762 ± 1.218
0.0TyrHis: 0.0 ± 0.0
1.381TyrIle: 1.381 ± 0.765
2.762TyrLys: 2.762 ± 1.218
2.762TyrLeu: 2.762 ± 1.531
0.0TyrMet: 0.0 ± 0.0
2.762TyrAsn: 2.762 ± 1.218
2.762TyrPro: 2.762 ± 1.531
4.144TyrGln: 4.144 ± 2.842
4.144TyrArg: 4.144 ± 2.842
5.525TyrSer: 5.525 ± 0.825
2.762TyrThr: 2.762 ± 1.531
1.381TyrVal: 1.381 ± 0.765
1.381TyrTrp: 1.381 ± 0.765
2.762TyrTyr: 2.762 ± 1.218
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (725 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski