Amino acid dipepetide frequency for Haloechinothrix alba

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.826AlaAla: 17.826 ± 0.188	1.172AlaCys: 1.172 ± 0.033	7.901AlaAsp: 7.901 ± 0.085	10.021AlaGlu: 10.021 ± 0.104	3.276AlaPhe: 3.276 ± 0.047	13.209AlaGly: 13.209 ± 0.128	2.749AlaHis: 2.749 ± 0.043	4.185AlaIle: 4.185 ± 0.059	2.233AlaLys: 2.233 ± 0.044	12.451AlaLeu: 12.451 ± 0.127	2.615AlaMet: 2.615 ± 0.047	2.047AlaAsn: 2.047 ± 0.042	5.467AlaPro: 5.467 ± 0.071	3.39AlaGln: 3.39 ± 0.048	9.971AlaArg: 9.971 ± 0.105	6.089AlaSer: 6.089 ± 0.077	6.965AlaThr: 6.965 ± 0.079	11.197AlaVal: 11.197 ± 0.104	1.594AlaTrp: 1.594 ± 0.039	2.289AlaTyr: 2.289 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	1.154CysAla: 1.154 ± 0.029	0.11CysCys: 0.11 ± 0.009	0.532CysAsp: 0.532 ± 0.019	0.473CysGlu: 0.473 ± 0.019	0.202CysPhe: 0.202 ± 0.012	0.987CysGly: 0.987 ± 0.028	0.223CysHis: 0.223 ± 0.013	0.238CysIle: 0.238 ± 0.013	0.11CysLys: 0.11 ± 0.008	0.673CysLeu: 0.673 ± 0.024	0.136CysMet: 0.136 ± 0.01	0.136CysAsn: 0.136 ± 0.011	0.509CysPro: 0.509 ± 0.02	0.191CysGln: 0.191 ± 0.011	0.664CysArg: 0.664 ± 0.024	0.522CysSer: 0.522 ± 0.02	0.529CysThr: 0.529 ± 0.021	0.75CysVal: 0.75 ± 0.024	0.134CysTrp: 0.134 ± 0.01	0.198CysTyr: 0.198 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.902AspAla: 7.902 ± 0.084	0.423AspCys: 0.423 ± 0.019	3.899AspAsp: 3.899 ± 0.054	5.173AspGlu: 5.173 ± 0.063	1.548AspPhe: 1.548 ± 0.037	6.637AspGly: 6.637 ± 0.08	1.321AspHis: 1.321 ± 0.028	2.282AspIle: 2.282 ± 0.048	1.095AspLys: 1.095 ± 0.032	5.706AspLeu: 5.706 ± 0.066	0.929AspMet: 0.929 ± 0.025	1.131AspAsn: 1.131 ± 0.032	4.513AspPro: 4.513 ± 0.061	1.617AspGln: 1.617 ± 0.038	4.875AspArg: 4.875 ± 0.065	3.299AspSer: 3.299 ± 0.049	3.644AspThr: 3.644 ± 0.052	5.802AspVal: 5.802 ± 0.066	0.873AspTrp: 0.873 ± 0.025	1.283AspTyr: 1.283 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	7.186GluAla: 7.186 ± 0.082	0.446GluCys: 0.446 ± 0.018	3.292GluAsp: 3.292 ± 0.057	3.876GluGlu: 3.876 ± 0.063	1.895GluPhe: 1.895 ± 0.037	4.407GluGly: 4.407 ± 0.075	2.251GluHis: 2.251 ± 0.042	2.752GluIle: 2.752 ± 0.051	1.151GluLys: 1.151 ± 0.035	8.416GluLeu: 8.416 ± 0.088	1.202GluMet: 1.202 ± 0.029	1.129GluAsn: 1.129 ± 0.029	4.042GluPro: 4.042 ± 0.066	3.151GluGln: 3.151 ± 0.055	6.422GluArg: 6.422 ± 0.071	3.427GluSer: 3.427 ± 0.055	2.969GluThr: 2.969 ± 0.044	5.467GluVal: 5.467 ± 0.064	0.925GluTrp: 0.925 ± 0.026	1.284GluTyr: 1.284 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.635PheAla: 3.635 ± 0.054	0.273PheCys: 0.273 ± 0.014	2.213PheAsp: 2.213 ± 0.041	1.472PheGlu: 1.472 ± 0.033	0.787PhePhe: 0.787 ± 0.027	3.111PheGly: 3.111 ± 0.047	0.626PheHis: 0.626 ± 0.022	0.782PheIle: 0.782 ± 0.026	0.34PheLys: 0.34 ± 0.015	2.428PheLeu: 2.428 ± 0.048	0.377PheMet: 0.377 ± 0.017	0.547PheAsn: 0.547 ± 0.02	1.228PhePro: 1.228 ± 0.029	0.589PheGln: 0.589 ± 0.018	1.768PheArg: 1.768 ± 0.033	1.48PheSer: 1.48 ± 0.031	1.927PheThr: 1.927 ± 0.03	2.444PheVal: 2.444 ± 0.044	0.36PheTrp: 0.36 ± 0.017	0.58PheTyr: 0.58 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	10.329GlyAla: 10.329 ± 0.09	0.862GlyCys: 0.862 ± 0.026	5.568GlyAsp: 5.568 ± 0.07	6.185GlyGlu: 6.185 ± 0.074	2.749GlyPhe: 2.749 ± 0.052	8.488GlyGly: 8.488 ± 0.125	2.279GlyHis: 2.279 ± 0.043	3.743GlyIle: 3.743 ± 0.051	2.233GlyLys: 2.233 ± 0.049	8.63GlyLeu: 8.63 ± 0.091	2.319GlyMet: 2.319 ± 0.039	1.835GlyAsn: 1.835 ± 0.04	4.376GlyPro: 4.376 ± 0.055	2.921GlyGln: 2.921 ± 0.056	6.724GlyArg: 6.724 ± 0.064	5.997GlySer: 5.997 ± 0.071	6.316GlyThr: 6.316 ± 0.08	7.88GlyVal: 7.88 ± 0.081	1.586GlyTrp: 1.586 ± 0.035	2.331GlyTyr: 2.331 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	3.004HisAla: 3.004 ± 0.058	0.216HisCys: 0.216 ± 0.012	1.481HisAsp: 1.481 ± 0.03	1.466HisGlu: 1.466 ± 0.031	0.601HisPhe: 0.601 ± 0.021	2.583HisGly: 2.583 ± 0.048	0.715HisHis: 0.715 ± 0.026	0.782HisIle: 0.782 ± 0.024	0.376HisLys: 0.376 ± 0.016	2.151HisLeu: 2.151 ± 0.036	0.369HisMet: 0.369 ± 0.016	0.439HisAsn: 0.439 ± 0.018	1.705HisPro: 1.705 ± 0.037	0.664HisGln: 0.664 ± 0.021	2.096HisArg: 2.096 ± 0.038	1.217HisSer: 1.217 ± 0.028	1.364HisThr: 1.364 ± 0.036	1.958HisVal: 1.958 ± 0.032	0.322HisTrp: 0.322 ± 0.014	0.557HisTyr: 0.557 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.214IleAla: 5.214 ± 0.061	0.3IleCys: 0.3 ± 0.014	2.907IleAsp: 2.907 ± 0.046	2.432IleGlu: 2.432 ± 0.035	0.763IlePhe: 0.763 ± 0.024	3.798IleGly: 3.798 ± 0.052	0.672IleHis: 0.672 ± 0.023	1.063IleIle: 1.063 ± 0.03	0.67IleLys: 0.67 ± 0.023	2.382IleLeu: 2.382 ± 0.048	0.471IleMet: 0.471 ± 0.02	0.891IleAsn: 0.891 ± 0.028	1.884IlePro: 1.884 ± 0.03	0.728IleGln: 0.728 ± 0.026	2.344IleArg: 2.344 ± 0.042	2.043IleSer: 2.043 ± 0.04	2.441IleThr: 2.441 ± 0.045	3.12IleVal: 3.12 ± 0.05	0.383IleTrp: 0.383 ± 0.019	0.688IleTyr: 0.688 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	2.089LysAla: 2.089 ± 0.043	0.099LysCys: 0.099 ± 0.01	0.959LysAsp: 0.959 ± 0.029	0.964LysGlu: 0.964 ± 0.028	0.396LysPhe: 0.396 ± 0.019	1.369LysGly: 1.369 ± 0.033	0.478LysHis: 0.478 ± 0.019	0.752LysIle: 0.752 ± 0.022	0.517LysLys: 0.517 ± 0.026	1.933LysLeu: 1.933 ± 0.043	0.332LysMet: 0.332 ± 0.015	0.38LysAsn: 0.38 ± 0.016	1.143LysPro: 1.143 ± 0.035	0.727LysGln: 0.727 ± 0.025	1.57LysArg: 1.57 ± 0.037	1.035LysSer: 1.035 ± 0.033	0.925LysThr: 0.925 ± 0.023	1.589LysVal: 1.589 ± 0.039	0.212LysTrp: 0.212 ± 0.013	0.369LysTyr: 0.369 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	14.393LeuAla: 14.393 ± 0.144	0.818LeuCys: 0.818 ± 0.024	7.134LeuAsp: 7.134 ± 0.082	5.339LeuGlu: 5.339 ± 0.071	2.416LeuPhe: 2.416 ± 0.046	9.203LeuGly: 9.203 ± 0.09	2.234LeuHis: 2.234 ± 0.043	3.086LeuIle: 3.086 ± 0.052	1.303LeuLys: 1.303 ± 0.031	9.858LeuLeu: 9.858 ± 0.127	1.467LeuMet: 1.467 ± 0.03	1.682LeuAsn: 1.682 ± 0.03	5.714LeuPro: 5.714 ± 0.077	2.011LeuGln: 2.011 ± 0.037	8.652LeuArg: 8.652 ± 0.097	5.45LeuSer: 5.45 ± 0.065	5.934LeuThr: 5.934 ± 0.069	8.724LeuVal: 8.724 ± 0.103	1.118LeuTrp: 1.118 ± 0.029	1.674LeuTyr: 1.674 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.219MetAla: 2.219 ± 0.036	0.167MetCys: 0.167 ± 0.011	0.924MetAsp: 0.924 ± 0.026	0.787MetGlu: 0.787 ± 0.023	0.557MetPhe: 0.557 ± 0.021	1.314MetGly: 1.314 ± 0.03	0.444MetHis: 0.444 ± 0.018	0.782MetIle: 0.782 ± 0.023	0.359MetLys: 0.359 ± 0.016	2.034MetLeu: 2.034 ± 0.041	0.337MetMet: 0.337 ± 0.018	0.485MetAsn: 0.485 ± 0.019	1.242MetPro: 1.242 ± 0.026	0.488MetGln: 0.488 ± 0.02	1.711MetArg: 1.711 ± 0.039	1.47MetSer: 1.47 ± 0.033	1.635MetThr: 1.635 ± 0.033	1.413MetVal: 1.413 ± 0.035	0.21MetTrp: 0.21 ± 0.013	0.299MetTyr: 0.299 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.302AsnAla: 2.302 ± 0.046	0.164AsnCys: 0.164 ± 0.011	1.093AsnAsp: 1.093 ± 0.025	1.167AsnGlu: 1.167 ± 0.03	0.494AsnPhe: 0.494 ± 0.019	1.727AsnGly: 1.727 ± 0.039	0.408AsnHis: 0.408 ± 0.019	0.709AsnIle: 0.709 ± 0.027	0.383AsnLys: 0.383 ± 0.017	1.776AsnLeu: 1.776 ± 0.039	0.322AsnMet: 0.322 ± 0.016	0.427AsnAsn: 0.427 ± 0.02	1.356AsnPro: 1.356 ± 0.034	0.593AsnGln: 0.593 ± 0.019	1.361AsnArg: 1.361 ± 0.033	1.008AsnSer: 1.008 ± 0.029	1.11AsnThr: 1.11 ± 0.03	1.563AsnVal: 1.563 ± 0.037	0.266AsnTrp: 0.266 ± 0.015	0.441AsnTyr: 0.441 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.932ProAla: 6.932 ± 0.08	0.38ProCys: 0.38 ± 0.017	4.577ProAsp: 4.577 ± 0.063	4.587ProGlu: 4.587 ± 0.072	1.455ProPhe: 1.455 ± 0.034	5.888ProGly: 5.888 ± 0.087	1.371ProHis: 1.371 ± 0.029	1.628ProIle: 1.628 ± 0.04	0.905ProLys: 0.905 ± 0.027	4.569ProLeu: 4.569 ± 0.065	1.011ProMet: 1.011 ± 0.028	0.979ProAsn: 0.979 ± 0.03	2.939ProPro: 2.939 ± 0.06	1.528ProGln: 1.528 ± 0.036	3.649ProArg: 3.649 ± 0.054	3.032ProSer: 3.032 ± 0.052	2.958ProThr: 2.958 ± 0.043	5.075ProVal: 5.075 ± 0.065	0.808ProTrp: 0.808 ± 0.023	1.17ProTyr: 1.17 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.718GlnAla: 3.718 ± 0.057	0.221GlnCys: 0.221 ± 0.014	1.531GlnAsp: 1.531 ± 0.035	1.579GlnGlu: 1.579 ± 0.036	0.72GlnPhe: 0.72 ± 0.023	2.147GlnGly: 2.147 ± 0.045	0.813GlnHis: 0.813 ± 0.028	1.033GlnIle: 1.033 ± 0.03	0.421GlnLys: 0.421 ± 0.019	3.386GlnLeu: 3.386 ± 0.047	0.553GlnMet: 0.553 ± 0.02	0.466GlnAsn: 0.466 ± 0.019	1.788GlnPro: 1.788 ± 0.043	1.464GlnGln: 1.464 ± 0.051	2.985GlnArg: 2.985 ± 0.051	1.295GlnSer: 1.295 ± 0.031	1.144GlnThr: 1.144 ± 0.029	2.446GlnVal: 2.446 ± 0.041	0.435GlnTrp: 0.435 ± 0.016	0.582GlnTyr: 0.582 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.721ArgAla: 9.721 ± 0.103	0.709ArgCys: 0.709 ± 0.024	4.752ArgAsp: 4.752 ± 0.058	5.205ArgGlu: 5.205 ± 0.064	2.41ArgPhe: 2.41 ± 0.044	5.761ArgGly: 5.761 ± 0.064	2.132ArgHis: 2.132 ± 0.039	3.187ArgIle: 3.187 ± 0.045	1.802ArgLys: 1.802 ± 0.045	7.835ArgLeu: 7.835 ± 0.089	2.036ArgMet: 2.036 ± 0.033	1.553ArgAsn: 1.553 ± 0.035	4.308ArgPro: 4.308 ± 0.066	2.602ArgGln: 2.602 ± 0.045	7.259ArgArg: 7.259 ± 0.105	4.713ArgSer: 4.713 ± 0.055	4.84ArgThr: 4.84 ± 0.067	6.4ArgVal: 6.4 ± 0.068	1.378ArgTrp: 1.378 ± 0.033	2.037ArgTyr: 2.037 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	6.844SerAla: 6.844 ± 0.072	0.487SerCys: 0.487 ± 0.02	3.37SerAsp: 3.37 ± 0.05	3.607SerGlu: 3.607 ± 0.055	1.574SerPhe: 1.574 ± 0.033	6.57SerGly: 6.57 ± 0.084	1.052SerHis: 1.052 ± 0.027	1.732SerIle: 1.732 ± 0.038	1.025SerLys: 1.025 ± 0.031	4.867SerLeu: 4.867 ± 0.062	1.284SerMet: 1.284 ± 0.032	1.01SerAsn: 1.01 ± 0.026	2.872SerPro: 2.872 ± 0.048	1.353SerGln: 1.353 ± 0.03	4.062SerArg: 4.062 ± 0.063	3.191SerSer: 3.191 ± 0.05	3.565SerThr: 3.565 ± 0.05	4.759SerVal: 4.759 ± 0.055	0.938SerTrp: 0.938 ± 0.028	1.292SerTyr: 1.292 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	7.53ThrAla: 7.53 ± 0.077	0.489ThrCys: 0.489 ± 0.017	3.702ThrAsp: 3.702 ± 0.054	4.076ThrGlu: 4.076 ± 0.056	1.613ThrPhe: 1.613 ± 0.033	6.419ThrGly: 6.419 ± 0.082	1.243ThrHis: 1.243 ± 0.03	2.109ThrIle: 2.109 ± 0.037	1.048ThrLys: 1.048 ± 0.033	5.353ThrLeu: 5.353 ± 0.067	1.12ThrMet: 1.12 ± 0.03	1.012ThrAsn: 1.012 ± 0.029	3.352ThrPro: 3.352 ± 0.05	1.354ThrGln: 1.354 ± 0.033	4.066ThrArg: 4.066 ± 0.062	3.437ThrSer: 3.437 ± 0.058	3.666ThrThr: 3.666 ± 0.058	6.078ThrVal: 6.078 ± 0.071	0.856ThrTrp: 0.856 ± 0.03	1.196ThrTyr: 1.196 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	10.968ValAla: 10.968 ± 0.111	0.744ValCys: 0.744 ± 0.025	6.055ValAsp: 6.055 ± 0.074	5.335ValGlu: 5.335 ± 0.062	2.337ValPhe: 2.337 ± 0.044	6.733ValGly: 6.733 ± 0.071	2.198ValHis: 2.198 ± 0.041	3.201ValIle: 3.201 ± 0.055	1.296ValLys: 1.296 ± 0.036	9.752ValLeu: 9.752 ± 0.104	1.398ValMet: 1.398 ± 0.036	1.786ValAsn: 1.786 ± 0.039	5.082ValPro: 5.082 ± 0.06	2.092ValGln: 2.092 ± 0.042	7.167ValArg: 7.167 ± 0.085	4.742ValSer: 4.742 ± 0.056	5.833ValThr: 5.833 ± 0.064	8.149ValVal: 8.149 ± 0.085	1.006ValTrp: 1.006 ± 0.03	1.553ValTyr: 1.553 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.327TrpAla: 1.327 ± 0.032	0.172TrpCys: 0.172 ± 0.01	0.723TrpAsp: 0.723 ± 0.022	0.688TrpGlu: 0.688 ± 0.024	0.508TrpPhe: 0.508 ± 0.019	0.894TrpGly: 0.894 ± 0.024	0.396TrpHis: 0.396 ± 0.016	0.53TrpIle: 0.53 ± 0.021	0.267TrpLys: 0.267 ± 0.015	1.799TrpLeu: 1.799 ± 0.045	0.34TrpMet: 0.34 ± 0.017	0.351TrpAsn: 0.351 ± 0.018	0.76TrpPro: 0.76 ± 0.024	0.649TrpGln: 0.649 ± 0.023	1.316TrpArg: 1.316 ± 0.031	0.912TrpSer: 0.912 ± 0.028	0.77TrpThr: 0.77 ± 0.024	1.025TrpVal: 1.025 ± 0.027	0.348TrpTrp: 0.348 ± 0.016	0.297TrpTyr: 0.297 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.357TyrAla: 2.357 ± 0.042	0.219TyrCys: 0.219 ± 0.011	1.341TyrAsp: 1.341 ± 0.037	1.26TyrGlu: 1.26 ± 0.031	0.667TyrPhe: 0.667 ± 0.021	2.109TyrGly: 2.109 ± 0.04	0.459TyrHis: 0.459 ± 0.019	0.616TyrIle: 0.616 ± 0.022	0.304TyrLys: 0.304 ± 0.017	2.211TyrLeu: 2.211 ± 0.038	0.257TyrMet: 0.257 ± 0.012	0.382TyrAsn: 0.382 ± 0.019	1.158TyrPro: 1.158 ± 0.029	0.618TyrGln: 0.618 ± 0.02	1.977TyrArg: 1.977 ± 0.037	1.093TyrSer: 1.093 ± 0.033	1.184TyrThr: 1.184 ± 0.033	1.589TyrVal: 1.589 ± 0.034	0.319TyrTrp: 0.319 ± 0.014	0.462TyrTyr: 0.462 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4481 proteins (1395595 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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