Amino acid dipepetide frequency for Channa argus (northern snakehead)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.892AlaAla: 5.892 ± 0.041	1.228AlaCys: 1.228 ± 0.012	3.049AlaAsp: 3.049 ± 0.016	4.511AlaGlu: 4.511 ± 0.027	2.277AlaPhe: 2.277 ± 0.015	4.119AlaGly: 4.119 ± 0.023	1.467AlaHis: 1.467 ± 0.011	2.709AlaIle: 2.709 ± 0.018	3.351AlaLys: 3.351 ± 0.025	6.292AlaLeu: 6.292 ± 0.037	1.538AlaMet: 1.538 ± 0.013	2.192AlaAsn: 2.192 ± 0.015	3.333AlaPro: 3.333 ± 0.027	2.894AlaGln: 2.894 ± 0.02	2.955AlaArg: 2.955 ± 0.025	5.366AlaSer: 5.366 ± 0.029	3.54AlaThr: 3.54 ± 0.022	4.794AlaVal: 4.794 ± 0.025	0.623AlaTrp: 0.623 ± 0.009	1.439AlaTyr: 1.439 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	1.146CysAla: 1.146 ± 0.012	0.672CysCys: 0.672 ± 0.011	1.148CysAsp: 1.148 ± 0.016	1.272CysGlu: 1.272 ± 0.017	0.887CysPhe: 0.887 ± 0.009	1.549CysGly: 1.549 ± 0.018	0.674CysHis: 0.674 ± 0.009	0.992CysIle: 0.992 ± 0.014	1.181CysLys: 1.181 ± 0.012	2.201CysLeu: 2.201 ± 0.018	0.476CysMet: 0.476 ± 0.007	0.879CysAsn: 0.879 ± 0.011	1.337CysPro: 1.337 ± 0.02	1.094CysGln: 1.094 ± 0.013	1.273CysArg: 1.273 ± 0.013	2.192CysSer: 2.192 ± 0.019	1.231CysThr: 1.231 ± 0.013	1.537CysVal: 1.537 ± 0.016	0.318CysTrp: 0.318 ± 0.013	0.645CysTyr: 0.645 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	2.77AspAla: 2.77 ± 0.018	1.155AspCys: 1.155 ± 0.014	3.049AspAsp: 3.049 ± 0.025	3.746AspGlu: 3.746 ± 0.024	2.069AspPhe: 2.069 ± 0.015	3.498AspGly: 3.498 ± 0.026	1.216AspHis: 1.216 ± 0.017	2.739AspIle: 2.739 ± 0.024	2.826AspLys: 2.826 ± 0.019	4.865AspLeu: 4.865 ± 0.029	1.304AspMet: 1.304 ± 0.011	2.033AspAsn: 2.033 ± 0.014	2.777AspPro: 2.777 ± 0.018	2.011AspGln: 2.011 ± 0.016	2.713AspArg: 2.713 ± 0.019	4.541AspSer: 4.541 ± 0.023	2.77AspThr: 2.77 ± 0.017	3.245AspVal: 3.245 ± 0.02	0.66AspTrp: 0.66 ± 0.008	1.514AspTyr: 1.514 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	4.536GluAla: 4.536 ± 0.026	1.224GluCys: 1.224 ± 0.015	4.454GluAsp: 4.454 ± 0.023	7.831GluGlu: 7.831 ± 0.058	1.898GluPhe: 1.898 ± 0.014	4.104GluGly: 4.104 ± 0.022	1.511GluHis: 1.511 ± 0.019	2.91GluIle: 2.91 ± 0.023	4.853GluLys: 4.853 ± 0.041	6.1GluLeu: 6.1 ± 0.037	1.77GluMet: 1.77 ± 0.012	2.86GluAsn: 2.86 ± 0.02	2.796GluPro: 2.796 ± 0.022	3.208GluGln: 3.208 ± 0.026	4.222GluArg: 4.222 ± 0.031	4.411GluSer: 4.411 ± 0.024	3.613GluThr: 3.613 ± 0.038	4.326GluVal: 4.326 ± 0.027	0.673GluTrp: 0.673 ± 0.008	1.553GluTyr: 1.553 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	1.854PheAla: 1.854 ± 0.013	0.954PheCys: 0.954 ± 0.01	1.709PheAsp: 1.709 ± 0.013	1.804PheGlu: 1.804 ± 0.014	1.529PhePhe: 1.529 ± 0.014	2.112PheGly: 2.112 ± 0.016	1.008PheHis: 1.008 ± 0.009	1.894PheIle: 1.894 ± 0.016	1.793PheLys: 1.793 ± 0.015	3.743PheLeu: 3.743 ± 0.024	0.801PheMet: 0.801 ± 0.008	1.473PheAsn: 1.473 ± 0.012	1.805PhePro: 1.805 ± 0.014	1.578PheGln: 1.578 ± 0.014	1.805PheArg: 1.805 ± 0.019	3.397PheSer: 3.397 ± 0.021	2.306PheThr: 2.306 ± 0.013	2.172PheVal: 2.172 ± 0.017	0.446PheTrp: 0.446 ± 0.006	1.193PheTyr: 1.193 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	3.832GlyAla: 3.832 ± 0.023	1.258GlyCys: 1.258 ± 0.013	3.18GlyAsp: 3.18 ± 0.019	4.077GlyGlu: 4.077 ± 0.031	2.367GlyPhe: 2.367 ± 0.02	5.266GlyGly: 5.266 ± 0.052	1.686GlyHis: 1.686 ± 0.016	2.622GlyIle: 2.622 ± 0.018	3.579GlyLys: 3.579 ± 0.035	5.468GlyLeu: 5.468 ± 0.028	1.423GlyMet: 1.423 ± 0.015	2.492GlyAsn: 2.492 ± 0.02	3.278GlyPro: 3.278 ± 0.05	2.788GlyGln: 2.788 ± 0.018	3.471GlyArg: 3.471 ± 0.024	5.706GlySer: 5.706 ± 0.036	3.387GlyThr: 3.387 ± 0.021	3.903GlyVal: 3.903 ± 0.024	0.759GlyTrp: 0.759 ± 0.019	1.795GlyTyr: 1.795 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.269HisAla: 1.269 ± 0.01	0.796HisCys: 0.796 ± 0.01	0.982HisAsp: 0.982 ± 0.01	1.207HisGlu: 1.207 ± 0.011	1.055HisPhe: 1.055 ± 0.01	1.536HisGly: 1.536 ± 0.013	1.131HisHis: 1.131 ± 0.014	1.372HisIle: 1.372 ± 0.011	1.366HisLys: 1.366 ± 0.011	2.762HisLeu: 2.762 ± 0.019	0.701HisMet: 0.701 ± 0.008	1.081HisAsn: 1.081 ± 0.01	1.652HisPro: 1.652 ± 0.037	1.346HisGln: 1.346 ± 0.013	1.641HisArg: 1.641 ± 0.012	2.612HisSer: 2.612 ± 0.022	1.687HisThr: 1.687 ± 0.016	1.452HisVal: 1.452 ± 0.01	0.34HisTrp: 0.34 ± 0.005	0.869HisTyr: 0.869 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	2.476IleAla: 2.476 ± 0.015	1.123IleCys: 1.123 ± 0.011	2.076IleAsp: 2.076 ± 0.015	2.424IleGlu: 2.424 ± 0.018	1.777IlePhe: 1.777 ± 0.017	2.309IleGly: 2.309 ± 0.016	1.305IleHis: 1.305 ± 0.011	2.466IleIle: 2.466 ± 0.021	2.651IleLys: 2.651 ± 0.022	4.308IleLeu: 4.308 ± 0.026	1.078IleMet: 1.078 ± 0.009	1.994IleAsn: 1.994 ± 0.015	2.504IlePro: 2.504 ± 0.016	2.262IleGln: 2.262 ± 0.015	2.396IleArg: 2.396 ± 0.014	3.95IleSer: 3.95 ± 0.02	2.89IleThr: 2.89 ± 0.021	2.605IleVal: 2.605 ± 0.02	0.487IleTrp: 0.487 ± 0.008	1.386IleTyr: 1.386 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	3.744LysAla: 3.744 ± 0.027	1.078LysCys: 1.078 ± 0.013	3.335LysAsp: 3.335 ± 0.024	4.897LysGlu: 4.897 ± 0.044	1.544LysPhe: 1.544 ± 0.015	3.283LysGly: 3.283 ± 0.03	1.493LysHis: 1.493 ± 0.02	2.508LysIle: 2.508 ± 0.018	4.634LysLys: 4.634 ± 0.037	5.011LysLeu: 5.011 ± 0.031	1.516LysMet: 1.516 ± 0.014	2.373LysAsn: 2.373 ± 0.016	3.001LysPro: 3.001 ± 0.035	2.658LysGln: 2.658 ± 0.02	3.471LysArg: 3.471 ± 0.02	3.949LysSer: 3.949 ± 0.027	3.386LysThr: 3.386 ± 0.022	3.556LysVal: 3.556 ± 0.022	0.577LysTrp: 0.577 ± 0.009	1.488LysTyr: 1.488 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	5.907LeuAla: 5.907 ± 0.032	2.26LeuCys: 2.26 ± 0.02	4.763LeuAsp: 4.763 ± 0.028	6.324LeuGlu: 6.324 ± 0.045	3.304LeuPhe: 3.304 ± 0.022	5.02LeuGly: 5.02 ± 0.027	2.756LeuHis: 2.756 ± 0.019	3.842LeuIle: 3.842 ± 0.024	5.665LeuLys: 5.665 ± 0.038	9.993LeuLeu: 9.993 ± 0.056	2.14LeuMet: 2.14 ± 0.015	3.684LeuAsn: 3.684 ± 0.02	5.327LeuPro: 5.327 ± 0.033	5.485LeuGln: 5.485 ± 0.031	5.431LeuArg: 5.431 ± 0.024	8.536LeuSer: 8.536 ± 0.038	5.321LeuThr: 5.321 ± 0.026	5.462LeuVal: 5.462 ± 0.026	1.053LeuTrp: 1.053 ± 0.01	2.597LeuTyr: 2.597 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	1.899MetAla: 1.899 ± 0.014	0.494MetCys: 0.494 ± 0.007	1.439MetAsp: 1.439 ± 0.011	1.995MetGlu: 1.995 ± 0.013	0.858MetPhe: 0.858 ± 0.009	1.417MetGly: 1.417 ± 0.014	0.506MetHis: 0.506 ± 0.007	0.894MetIle: 0.894 ± 0.011	1.515MetLys: 1.515 ± 0.012	2.1MetLeu: 2.1 ± 0.016	0.711MetMet: 0.711 ± 0.009	0.906MetAsn: 0.906 ± 0.009	1.092MetPro: 1.092 ± 0.014	1.01MetGln: 1.01 ± 0.01	1.162MetArg: 1.162 ± 0.011	1.947MetSer: 1.947 ± 0.013	1.305MetThr: 1.305 ± 0.011	1.536MetVal: 1.536 ± 0.012	0.266MetTrp: 0.266 ± 0.005	0.631MetTyr: 0.631 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.095AsnAla: 2.095 ± 0.014	0.922AsnCys: 0.922 ± 0.016	1.715AsnAsp: 1.715 ± 0.014	2.182AsnGlu: 2.182 ± 0.017	1.401AsnPhe: 1.401 ± 0.013	2.72AsnGly: 2.72 ± 0.024	1.049AsnHis: 1.049 ± 0.009	2.243AsnIle: 2.243 ± 0.018	2.354AsnLys: 2.354 ± 0.017	3.69AsnLeu: 3.69 ± 0.023	1.09AsnMet: 1.09 ± 0.011	1.958AsnAsn: 1.958 ± 0.019	2.275AsnPro: 2.275 ± 0.017	1.845AsnGln: 1.845 ± 0.015	2.011AsnArg: 2.011 ± 0.013	3.428AsnSer: 3.428 ± 0.02	2.446AsnThr: 2.446 ± 0.019	2.374AsnVal: 2.374 ± 0.017	0.451AsnTrp: 0.451 ± 0.006	1.154AsnTyr: 1.154 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	3.943ProAla: 3.943 ± 0.028	1.111ProCys: 1.111 ± 0.013	2.805ProAsp: 2.805 ± 0.021	3.72ProGlu: 3.72 ± 0.029	1.751ProPhe: 1.751 ± 0.014	4.051ProGly: 4.051 ± 0.069	1.547ProHis: 1.547 ± 0.016	1.955ProIle: 1.955 ± 0.018	2.609ProLys: 2.609 ± 0.027	4.899ProLeu: 4.899 ± 0.025	1.045ProMet: 1.045 ± 0.01	1.976ProAsn: 1.976 ± 0.017	5.356ProPro: 5.356 ± 0.057	2.711ProGln: 2.711 ± 0.022	2.611ProArg: 2.611 ± 0.02	5.623ProSer: 5.623 ± 0.041	3.284ProThr: 3.284 ± 0.028	3.813ProVal: 3.813 ± 0.024	0.534ProTrp: 0.534 ± 0.007	1.423ProTyr: 1.423 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	3.119GlnAla: 3.119 ± 0.021	1.039GlnCys: 1.039 ± 0.013	2.365GlnAsp: 2.365 ± 0.017	3.55GlnGlu: 3.55 ± 0.026	1.348GlnPhe: 1.348 ± 0.012	2.755GlnGly: 2.755 ± 0.022	1.448GlnHis: 1.448 ± 0.013	1.991GlnIle: 1.991 ± 0.014	2.691GlnLys: 2.691 ± 0.018	4.581GlnLeu: 4.581 ± 0.03	1.171GlnMet: 1.171 ± 0.013	1.861GlnAsn: 1.861 ± 0.014	2.649GlnPro: 2.649 ± 0.024	3.527GlnGln: 3.527 ± 0.049	3.076GlnArg: 3.076 ± 0.019	3.712GlnSer: 3.712 ± 0.026	2.774GlnThr: 2.774 ± 0.018	2.803GlnVal: 2.803 ± 0.017	0.549GlnTrp: 0.549 ± 0.007	1.226GlnTyr: 1.226 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	3.285ArgAla: 3.285 ± 0.022	1.237ArgCys: 1.237 ± 0.019	2.852ArgAsp: 2.852 ± 0.021	3.921ArgGlu: 3.921 ± 0.031	1.865ArgPhe: 1.865 ± 0.013	3.447ArgGly: 3.447 ± 0.04	1.546ArgHis: 1.546 ± 0.013	2.325ArgIle: 2.325 ± 0.014	3.535ArgLys: 3.535 ± 0.021	5.096ArgLeu: 5.096 ± 0.025	1.266ArgMet: 1.266 ± 0.01	2.095ArgAsn: 2.095 ± 0.013	2.83ArgPro: 2.83 ± 0.021	2.691ArgGln: 2.691 ± 0.016	4.215ArgArg: 4.215 ± 0.029	4.427ArgSer: 4.427 ± 0.028	2.877ArgThr: 2.877 ± 0.018	3.218ArgVal: 3.218 ± 0.023	0.644ArgTrp: 0.644 ± 0.008	1.491ArgTyr: 1.491 ± 0.012	0.0ArgXaa: 0.0 ± 0.0
Ser	5.554SerAla: 5.554 ± 0.028	2.053SerCys: 2.053 ± 0.018	4.445SerAsp: 4.445 ± 0.025	5.034SerGlu: 5.034 ± 0.028	3.081SerPhe: 3.081 ± 0.02	5.6SerGly: 5.6 ± 0.033	2.386SerHis: 2.386 ± 0.017	3.451SerIle: 3.451 ± 0.02	4.16SerLys: 4.16 ± 0.025	8.46SerLeu: 8.46 ± 0.033	1.825SerMet: 1.825 ± 0.014	3.214SerAsn: 3.214 ± 0.021	6.07SerPro: 6.07 ± 0.049	4.054SerGln: 4.054 ± 0.026	4.449SerArg: 4.449 ± 0.032	10.834SerSer: 10.834 ± 0.068	5.228SerThr: 5.228 ± 0.036	5.577SerVal: 5.577 ± 0.03	0.986SerTrp: 0.986 ± 0.012	2.181SerTyr: 2.181 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	4.133ThrAla: 4.133 ± 0.026	1.4ThrCys: 1.4 ± 0.021	2.974ThrAsp: 2.974 ± 0.019	3.974ThrGlu: 3.974 ± 0.023	2.123ThrPhe: 2.123 ± 0.015	3.801ThrGly: 3.801 ± 0.027	1.475ThrHis: 1.475 ± 0.014	2.529ThrIle: 2.529 ± 0.019	2.844ThrLys: 2.844 ± 0.02	5.492ThrLeu: 5.492 ± 0.025	1.268ThrMet: 1.268 ± 0.011	2.118ThrAsn: 2.118 ± 0.014	3.658ThrPro: 3.658 ± 0.029	2.524ThrGln: 2.524 ± 0.017	2.488ThrArg: 2.488 ± 0.018	5.23ThrSer: 5.23 ± 0.042	3.925ThrThr: 3.925 ± 0.083	4.371ThrVal: 4.371 ± 0.029	0.669ThrTrp: 0.669 ± 0.01	1.453ThrTyr: 1.453 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	4.075ValAla: 4.075 ± 0.021	1.718ValCys: 1.718 ± 0.017	3.177ValAsp: 3.177 ± 0.02	4.108ValGlu: 4.108 ± 0.031	2.612ValPhe: 2.612 ± 0.019	3.49ValGly: 3.49 ± 0.02	1.596ValHis: 1.596 ± 0.012	2.992ValIle: 2.992 ± 0.019	3.68ValLys: 3.68 ± 0.03	6.128ValLeu: 6.128 ± 0.029	1.543ValMet: 1.543 ± 0.012	2.501ValAsn: 2.501 ± 0.02	3.298ValPro: 3.298 ± 0.029	2.809ValGln: 2.809 ± 0.018	3.131ValArg: 3.131 ± 0.016	5.449ValSer: 5.449 ± 0.033	4.119ValThr: 4.119 ± 0.031	4.482ValVal: 4.482 ± 0.061	0.758ValTrp: 0.758 ± 0.01	1.784ValTyr: 1.784 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	0.674TrpAla: 0.674 ± 0.017	0.245TrpCys: 0.245 ± 0.005	0.633TrpAsp: 0.633 ± 0.009	0.731TrpGlu: 0.731 ± 0.009	0.463TrpPhe: 0.463 ± 0.007	0.625TrpGly: 0.625 ± 0.011	0.265TrpHis: 0.265 ± 0.005	0.557TrpIle: 0.557 ± 0.008	0.724TrpLys: 0.724 ± 0.009	1.142TrpLeu: 1.142 ± 0.012	0.343TrpMet: 0.343 ± 0.005	0.493TrpAsn: 0.493 ± 0.006	0.42TrpPro: 0.42 ± 0.008	0.481TrpGln: 0.481 ± 0.007	0.715TrpArg: 0.715 ± 0.008	0.944TrpSer: 0.944 ± 0.013	0.709TrpThr: 0.709 ± 0.011	0.675TrpVal: 0.675 ± 0.008	0.182TrpTrp: 0.182 ± 0.004	0.332TrpTyr: 0.332 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.366TyrAla: 1.366 ± 0.011	0.738TyrCys: 0.738 ± 0.01	1.35TyrAsp: 1.35 ± 0.013	1.544TyrGlu: 1.544 ± 0.011	1.165TyrPhe: 1.165 ± 0.011	1.639TyrGly: 1.639 ± 0.014	0.792TyrHis: 0.792 ± 0.008	1.476TyrIle: 1.476 ± 0.014	1.488TyrLys: 1.488 ± 0.015	2.542TyrLeu: 2.542 ± 0.019	0.675TyrMet: 0.675 ± 0.007	1.218TyrAsn: 1.218 ± 0.01	1.31TyrPro: 1.31 ± 0.014	1.257TyrGln: 1.257 ± 0.01	1.626TyrArg: 1.626 ± 0.015	2.386TyrSer: 2.386 ± 0.015	1.653TyrThr: 1.653 ± 0.013	1.55TyrVal: 1.55 ± 0.014	0.379TyrTrp: 0.379 ± 0.007	0.974TyrTyr: 0.974 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 22260 proteins (12391188 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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