Amino acid dipepetide frequency for Klebsiella phage SH-Kp 152410

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.932AlaAla: 8.932 ± 1.052
0.738AlaCys: 0.738 ± 0.247
6.228AlaAsp: 6.228 ± 0.768
5.982AlaGlu: 5.982 ± 0.837
3.442AlaPhe: 3.442 ± 0.519
6.966AlaGly: 6.966 ± 1.21
1.557AlaHis: 1.557 ± 0.291
4.343AlaIle: 4.343 ± 0.526
6.802AlaLys: 6.802 ± 0.865
7.867AlaLeu: 7.867 ± 1.01
3.032AlaMet: 3.032 ± 0.62
4.589AlaAsn: 4.589 ± 0.464
2.54AlaPro: 2.54 ± 0.519
3.442AlaGln: 3.442 ± 0.68
5.49AlaArg: 5.49 ± 0.673
5.327AlaSer: 5.327 ± 0.619
3.278AlaThr: 3.278 ± 0.405
5.327AlaVal: 5.327 ± 0.711
1.229AlaTrp: 1.229 ± 0.32
2.95AlaTyr: 2.95 ± 0.427
0.0AlaXaa: 0.0 ± 0.0
Cys
0.574CysAla: 0.574 ± 0.22
0.246CysCys: 0.246 ± 0.154
0.656CysAsp: 0.656 ± 0.306
0.656CysGlu: 0.656 ± 0.251
0.41CysPhe: 0.41 ± 0.22
0.656CysGly: 0.656 ± 0.193
0.246CysHis: 0.246 ± 0.122
0.656CysIle: 0.656 ± 0.214
0.574CysLys: 0.574 ± 0.218
0.983CysLeu: 0.983 ± 0.308
0.082CysMet: 0.082 ± 0.092
0.328CysAsn: 0.328 ± 0.195
0.574CysPro: 0.574 ± 0.199
0.492CysGln: 0.492 ± 0.191
0.574CysArg: 0.574 ± 0.277
0.574CysSer: 0.574 ± 0.262
0.164CysThr: 0.164 ± 0.117
0.656CysVal: 0.656 ± 0.221
0.246CysTrp: 0.246 ± 0.155
0.328CysTyr: 0.328 ± 0.148
0.0CysXaa: 0.0 ± 0.0
Asp
5.654AspAla: 5.654 ± 0.678
0.738AspCys: 0.738 ± 0.305
4.179AspAsp: 4.179 ± 0.547
3.524AspGlu: 3.524 ± 0.507
3.196AspPhe: 3.196 ± 0.367
5.818AspGly: 5.818 ± 0.562
1.147AspHis: 1.147 ± 0.291
3.196AspIle: 3.196 ± 0.597
4.343AspLys: 4.343 ± 0.725
4.261AspLeu: 4.261 ± 0.731
2.131AspMet: 2.131 ± 0.362
2.704AspAsn: 2.704 ± 0.432
3.196AspPro: 3.196 ± 0.574
1.885AspGln: 1.885 ± 0.399
2.704AspArg: 2.704 ± 0.484
3.442AspSer: 3.442 ± 0.474
4.015AspThr: 4.015 ± 0.522
4.507AspVal: 4.507 ± 0.461
1.147AspTrp: 1.147 ± 0.369
2.213AspTyr: 2.213 ± 0.377
0.0AspXaa: 0.0 ± 0.0
Glu
7.047GluAla: 7.047 ± 0.826
0.41GluCys: 0.41 ± 0.186
4.425GluAsp: 4.425 ± 0.574
5.081GluGlu: 5.081 ± 0.824
2.786GluPhe: 2.786 ± 0.42
5.572GluGly: 5.572 ± 0.63
1.803GluHis: 1.803 ± 0.495
2.786GluIle: 2.786 ± 0.425
3.032GluLys: 3.032 ± 0.541
6.392GluLeu: 6.392 ± 0.965
1.885GluMet: 1.885 ± 0.591
2.376GluAsn: 2.376 ± 0.406
2.458GluPro: 2.458 ± 0.747
2.95GluGln: 2.95 ± 0.709
3.524GluArg: 3.524 ± 0.539
3.933GluSer: 3.933 ± 0.57
3.278GluThr: 3.278 ± 0.54
4.097GluVal: 4.097 ± 0.52
0.574GluTrp: 0.574 ± 0.207
2.868GluTyr: 2.868 ± 0.408
0.0GluXaa: 0.0 ± 0.0
Phe
2.786PheAla: 2.786 ± 0.451
0.328PheCys: 0.328 ± 0.204
2.786PheAsp: 2.786 ± 0.552
1.639PheGlu: 1.639 ± 0.393
0.983PhePhe: 0.983 ± 0.275
3.032PheGly: 3.032 ± 0.636
0.819PheHis: 0.819 ± 0.286
1.639PheIle: 1.639 ± 0.475
2.704PheLys: 2.704 ± 0.348
2.95PheLeu: 2.95 ± 0.501
1.065PheMet: 1.065 ± 0.29
2.54PheAsn: 2.54 ± 0.457
1.475PhePro: 1.475 ± 0.419
1.229PheGln: 1.229 ± 0.369
1.803PheArg: 1.803 ± 0.338
2.295PheSer: 2.295 ± 0.431
2.376PheThr: 2.376 ± 0.399
2.54PheVal: 2.54 ± 0.389
0.246PheTrp: 0.246 ± 0.105
0.901PheTyr: 0.901 ± 0.248
0.0PheXaa: 0.0 ± 0.0
Gly
7.129GlyAla: 7.129 ± 0.915
0.819GlyCys: 0.819 ± 0.263
5.327GlyAsp: 5.327 ± 0.541
5.245GlyGlu: 5.245 ± 0.659
2.868GlyPhe: 2.868 ± 0.369
6.31GlyGly: 6.31 ± 0.91
1.393GlyHis: 1.393 ± 0.281
5.163GlyIle: 5.163 ± 0.814
5.9GlyLys: 5.9 ± 0.925
6.474GlyLeu: 6.474 ± 0.887
1.803GlyMet: 1.803 ± 0.362
2.95GlyAsn: 2.95 ± 0.475
1.557GlyPro: 1.557 ± 0.586
2.868GlyGln: 2.868 ± 0.413
4.015GlyArg: 4.015 ± 0.363
5.409GlySer: 5.409 ± 0.59
3.852GlyThr: 3.852 ± 0.56
5.081GlyVal: 5.081 ± 0.799
1.639GlyTrp: 1.639 ± 0.393
4.343GlyTyr: 4.343 ± 0.562
0.0GlyXaa: 0.0 ± 0.0
His
1.065HisAla: 1.065 ± 0.302
0.41HisCys: 0.41 ± 0.156
1.229HisAsp: 1.229 ± 0.237
1.393HisGlu: 1.393 ± 0.401
0.656HisPhe: 0.656 ± 0.198
1.639HisGly: 1.639 ± 0.364
0.738HisHis: 0.738 ± 0.24
1.229HisIle: 1.229 ± 0.333
1.639HisLys: 1.639 ± 0.441
1.639HisLeu: 1.639 ± 0.547
0.656HisMet: 0.656 ± 0.241
0.738HisAsn: 0.738 ± 0.226
0.983HisPro: 0.983 ± 0.198
0.328HisGln: 0.328 ± 0.147
0.983HisArg: 0.983 ± 0.248
0.819HisSer: 0.819 ± 0.211
0.738HisThr: 0.738 ± 0.23
1.393HisVal: 1.393 ± 0.297
0.328HisTrp: 0.328 ± 0.169
0.819HisTyr: 0.819 ± 0.175
0.0HisXaa: 0.0 ± 0.0
Ile
4.507IleAla: 4.507 ± 0.506
0.738IleCys: 0.738 ± 0.226
3.442IleAsp: 3.442 ± 0.546
3.36IleGlu: 3.36 ± 0.724
0.656IlePhe: 0.656 ± 0.24
3.442IleGly: 3.442 ± 0.486
0.983IleHis: 0.983 ± 0.306
2.95IleIle: 2.95 ± 0.552
3.278IleLys: 3.278 ± 0.408
3.606IleLeu: 3.606 ± 0.568
1.065IleMet: 1.065 ± 0.296
2.295IleAsn: 2.295 ± 0.57
2.868IlePro: 2.868 ± 0.443
1.721IleGln: 1.721 ± 0.369
3.278IleArg: 3.278 ± 0.518
3.442IleSer: 3.442 ± 0.487
2.95IleThr: 2.95 ± 0.552
3.278IleVal: 3.278 ± 0.519
0.41IleTrp: 0.41 ± 0.179
1.967IleTyr: 1.967 ± 0.427
0.0IleXaa: 0.0 ± 0.0
Lys
7.785LysAla: 7.785 ± 1.082
0.574LysCys: 0.574 ± 0.213
4.343LysAsp: 4.343 ± 0.519
5.49LysGlu: 5.49 ± 0.709
2.54LysPhe: 2.54 ± 0.368
6.228LysGly: 6.228 ± 0.982
1.885LysHis: 1.885 ± 0.477
2.376LysIle: 2.376 ± 0.357
3.524LysLys: 3.524 ± 0.77
5.818LysLeu: 5.818 ± 0.649
1.639LysMet: 1.639 ± 0.417
2.868LysAsn: 2.868 ± 0.388
2.376LysPro: 2.376 ± 0.572
1.967LysGln: 1.967 ± 0.383
4.015LysArg: 4.015 ± 0.698
3.442LysSer: 3.442 ± 0.483
3.032LysThr: 3.032 ± 0.472
5.49LysVal: 5.49 ± 0.842
0.819LysTrp: 0.819 ± 0.303
2.295LysTyr: 2.295 ± 0.445
0.0LysXaa: 0.0 ± 0.0
Leu
7.211LeuAla: 7.211 ± 1.169
0.164LeuCys: 0.164 ± 0.111
4.753LeuAsp: 4.753 ± 0.556
7.047LeuGlu: 7.047 ± 1.077
2.295LeuPhe: 2.295 ± 0.405
5.245LeuGly: 5.245 ± 0.58
1.065LeuHis: 1.065 ± 0.272
3.032LeuIle: 3.032 ± 0.569
7.129LeuLys: 7.129 ± 0.719
5.736LeuLeu: 5.736 ± 0.873
1.967LeuMet: 1.967 ± 0.378
4.261LeuAsn: 4.261 ± 0.842
3.196LeuPro: 3.196 ± 0.513
3.606LeuGln: 3.606 ± 0.562
4.917LeuArg: 4.917 ± 0.648
5.163LeuSer: 5.163 ± 0.518
5.245LeuThr: 5.245 ± 0.783
5.409LeuVal: 5.409 ± 0.801
1.393LeuTrp: 1.393 ± 0.384
2.376LeuTyr: 2.376 ± 0.469
0.0LeuXaa: 0.0 ± 0.0
Met
3.442MetAla: 3.442 ± 0.496
0.164MetCys: 0.164 ± 0.121
1.967MetAsp: 1.967 ± 0.339
1.065MetGlu: 1.065 ± 0.274
1.065MetPhe: 1.065 ± 0.277
1.721MetGly: 1.721 ± 0.355
0.738MetHis: 0.738 ± 0.272
1.393MetIle: 1.393 ± 0.327
1.229MetLys: 1.229 ± 0.294
2.868MetLeu: 2.868 ± 0.528
0.492MetMet: 0.492 ± 0.206
0.983MetAsn: 0.983 ± 0.259
0.901MetPro: 0.901 ± 0.239
1.967MetGln: 1.967 ± 0.396
0.983MetArg: 0.983 ± 0.26
1.393MetSer: 1.393 ± 0.382
1.639MetThr: 1.639 ± 0.417
1.803MetVal: 1.803 ± 0.394
0.246MetTrp: 0.246 ± 0.145
0.574MetTyr: 0.574 ± 0.167
0.0MetXaa: 0.0 ± 0.0
Asn
4.097AsnAla: 4.097 ± 0.547
0.328AsnCys: 0.328 ± 0.186
2.049AsnAsp: 2.049 ± 0.316
2.458AsnGlu: 2.458 ± 0.503
1.803AsnPhe: 1.803 ± 0.516
4.343AsnGly: 4.343 ± 0.58
0.246AsnHis: 0.246 ± 0.16
2.704AsnIle: 2.704 ± 0.485
2.131AsnLys: 2.131 ± 0.429
3.196AsnLeu: 3.196 ± 0.52
0.983AsnMet: 0.983 ± 0.363
1.557AsnAsn: 1.557 ± 0.324
2.704AsnPro: 2.704 ± 0.396
1.147AsnGln: 1.147 ± 0.229
2.131AsnArg: 2.131 ± 0.614
3.36AsnSer: 3.36 ± 0.672
2.376AsnThr: 2.376 ± 0.404
3.278AsnVal: 3.278 ± 0.514
0.656AsnTrp: 0.656 ± 0.252
1.967AsnTyr: 1.967 ± 0.415
0.0AsnXaa: 0.0 ± 0.0
Pro
2.868ProAla: 2.868 ± 0.496
0.492ProCys: 0.492 ± 0.212
2.131ProAsp: 2.131 ± 0.387
4.343ProGlu: 4.343 ± 0.465
1.639ProPhe: 1.639 ± 0.301
2.131ProGly: 2.131 ± 0.415
0.41ProHis: 0.41 ± 0.175
1.229ProIle: 1.229 ± 0.345
2.868ProLys: 2.868 ± 0.568
2.458ProLeu: 2.458 ± 0.358
0.656ProMet: 0.656 ± 0.219
2.295ProAsn: 2.295 ± 0.414
0.819ProPro: 0.819 ± 0.356
1.229ProGln: 1.229 ± 0.276
1.639ProArg: 1.639 ± 0.275
2.213ProSer: 2.213 ± 0.326
2.295ProThr: 2.295 ± 0.592
2.868ProVal: 2.868 ± 0.403
0.901ProTrp: 0.901 ± 0.209
1.803ProTyr: 1.803 ± 0.404
0.0ProXaa: 0.0 ± 0.0
Gln
3.688GlnAla: 3.688 ± 0.617
0.082GlnCys: 0.082 ± 0.081
2.622GlnAsp: 2.622 ± 0.373
2.54GlnGlu: 2.54 ± 0.469
1.639GlnPhe: 1.639 ± 0.323
2.786GlnGly: 2.786 ± 0.458
0.328GlnHis: 0.328 ± 0.202
1.721GlnIle: 1.721 ± 0.399
2.786GlnLys: 2.786 ± 0.464
4.097GlnLeu: 4.097 ± 0.584
1.475GlnMet: 1.475 ± 0.409
1.147GlnAsn: 1.147 ± 0.245
1.311GlnPro: 1.311 ± 0.24
3.36GlnGln: 3.36 ± 0.559
2.131GlnArg: 2.131 ± 0.486
2.786GlnSer: 2.786 ± 0.52
1.557GlnThr: 1.557 ± 0.338
2.458GlnVal: 2.458 ± 0.455
0.656GlnTrp: 0.656 ± 0.229
1.557GlnTyr: 1.557 ± 0.46
0.0GlnXaa: 0.0 ± 0.0
Arg
4.753ArgAla: 4.753 ± 0.741
0.901ArgCys: 0.901 ± 0.298
3.278ArgAsp: 3.278 ± 0.526
3.852ArgGlu: 3.852 ± 0.527
1.721ArgPhe: 1.721 ± 0.351
4.343ArgGly: 4.343 ± 0.594
0.901ArgHis: 0.901 ± 0.276
2.95ArgIle: 2.95 ± 0.619
4.015ArgLys: 4.015 ± 0.555
4.015ArgLeu: 4.015 ± 0.631
1.475ArgMet: 1.475 ± 0.392
1.967ArgAsn: 1.967 ± 0.372
1.803ArgPro: 1.803 ± 0.365
2.704ArgGln: 2.704 ± 0.508
2.458ArgArg: 2.458 ± 0.39
3.278ArgSer: 3.278 ± 0.448
2.704ArgThr: 2.704 ± 0.44
3.852ArgVal: 3.852 ± 0.786
0.656ArgTrp: 0.656 ± 0.253
1.475ArgTyr: 1.475 ± 0.263
0.0ArgXaa: 0.0 ± 0.0
Ser
4.999SerAla: 4.999 ± 0.819
0.738SerCys: 0.738 ± 0.253
3.933SerAsp: 3.933 ± 0.459
2.868SerGlu: 2.868 ± 0.39
2.95SerPhe: 2.95 ± 0.461
5.572SerGly: 5.572 ± 0.874
1.803SerHis: 1.803 ± 0.393
3.196SerIle: 3.196 ± 0.498
4.917SerLys: 4.917 ± 0.535
4.835SerLeu: 4.835 ± 0.715
1.885SerMet: 1.885 ± 0.375
1.885SerAsn: 1.885 ± 0.58
1.967SerPro: 1.967 ± 0.373
2.622SerGln: 2.622 ± 0.466
3.278SerArg: 3.278 ± 0.501
2.95SerSer: 2.95 ± 0.46
3.852SerThr: 3.852 ± 0.85
3.606SerVal: 3.606 ± 0.444
0.901SerTrp: 0.901 ± 0.348
2.131SerTyr: 2.131 ± 0.442
0.0SerXaa: 0.0 ± 0.0
Thr
4.261ThrAla: 4.261 ± 0.702
0.901ThrCys: 0.901 ± 0.308
3.36ThrAsp: 3.36 ± 0.525
3.196ThrGlu: 3.196 ± 0.557
1.885ThrPhe: 1.885 ± 0.334
5.163ThrGly: 5.163 ± 0.757
1.065ThrHis: 1.065 ± 0.265
3.442ThrIle: 3.442 ± 0.441
4.425ThrLys: 4.425 ± 0.623
5.081ThrLeu: 5.081 ± 0.644
1.311ThrMet: 1.311 ± 0.326
1.721ThrAsn: 1.721 ± 0.454
2.786ThrPro: 2.786 ± 0.34
2.295ThrGln: 2.295 ± 0.413
2.458ThrArg: 2.458 ± 0.429
3.36ThrSer: 3.36 ± 0.653
2.704ThrThr: 2.704 ± 0.727
3.196ThrVal: 3.196 ± 0.651
0.492ThrTrp: 0.492 ± 0.251
1.475ThrTyr: 1.475 ± 0.477
0.0ThrXaa: 0.0 ± 0.0
Val
6.474ValAla: 6.474 ± 0.649
0.246ValCys: 0.246 ± 0.14
3.77ValAsp: 3.77 ± 0.647
4.261ValGlu: 4.261 ± 0.547
1.967ValPhe: 1.967 ± 0.524
5.081ValGly: 5.081 ± 0.546
1.229ValHis: 1.229 ± 0.403
3.688ValIle: 3.688 ± 0.566
4.179ValLys: 4.179 ± 0.516
5.163ValLeu: 5.163 ± 0.675
1.229ValMet: 1.229 ± 0.332
3.36ValAsn: 3.36 ± 0.618
2.376ValPro: 2.376 ± 0.433
2.622ValGln: 2.622 ± 0.417
3.688ValArg: 3.688 ± 0.562
4.671ValSer: 4.671 ± 0.878
5.654ValThr: 5.654 ± 0.733
4.261ValVal: 4.261 ± 0.579
0.738ValTrp: 0.738 ± 0.255
2.295ValTyr: 2.295 ± 0.563
0.0ValXaa: 0.0 ± 0.0
Trp
0.738TrpAla: 0.738 ± 0.211
0.492TrpCys: 0.492 ± 0.209
0.738TrpAsp: 0.738 ± 0.236
1.147TrpGlu: 1.147 ± 0.291
0.41TrpPhe: 0.41 ± 0.181
0.901TrpGly: 0.901 ± 0.308
0.328TrpHis: 0.328 ± 0.203
0.574TrpIle: 0.574 ± 0.252
1.393TrpLys: 1.393 ± 0.362
1.311TrpLeu: 1.311 ± 0.345
0.328TrpMet: 0.328 ± 0.166
0.738TrpAsn: 0.738 ± 0.218
0.328TrpPro: 0.328 ± 0.137
0.492TrpGln: 0.492 ± 0.153
0.738TrpArg: 0.738 ± 0.207
1.065TrpSer: 1.065 ± 0.349
0.738TrpThr: 0.738 ± 0.226
1.311TrpVal: 1.311 ± 0.334
0.246TrpTrp: 0.246 ± 0.141
0.082TrpTyr: 0.082 ± 0.072
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.049TyrAla: 2.049 ± 0.465
0.164TyrCys: 0.164 ± 0.114
2.786TyrAsp: 2.786 ± 0.433
2.213TyrGlu: 2.213 ± 0.45
1.229TyrPhe: 1.229 ± 0.257
3.196TyrGly: 3.196 ± 0.438
0.738TyrHis: 0.738 ± 0.241
1.967TyrIle: 1.967 ± 0.345
1.639TyrLys: 1.639 ± 0.294
2.458TyrLeu: 2.458 ± 0.463
1.393TyrMet: 1.393 ± 0.302
2.213TyrAsn: 2.213 ± 0.511
1.065TyrPro: 1.065 ± 0.249
1.803TyrGln: 1.803 ± 0.425
2.295TyrArg: 2.295 ± 0.354
1.967TyrSer: 1.967 ± 0.497
2.131TyrThr: 2.131 ± 0.478
2.54TyrVal: 2.54 ± 0.572
0.574TyrTrp: 0.574 ± 0.233
1.147TyrTyr: 1.147 ± 0.345
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 48 proteins (12204 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski