Amino acid dipepetide frequency for Stigmatella aurantiaca (strain DW4/3-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.785AlaAla: 13.785 ± 0.111	1.336AlaCys: 1.336 ± 0.027	4.67AlaAsp: 4.67 ± 0.041	7.504AlaGlu: 7.504 ± 0.078	3.92AlaPhe: 3.92 ± 0.042	9.336AlaGly: 9.336 ± 0.067	2.478AlaHis: 2.478 ± 0.032	3.497AlaIle: 3.497 ± 0.038	3.226AlaLys: 3.226 ± 0.047	14.624AlaLeu: 14.624 ± 0.12	2.277AlaMet: 2.277 ± 0.029	2.362AlaAsn: 2.362 ± 0.043	7.074AlaPro: 7.074 ± 0.069	4.906AlaGln: 4.906 ± 0.041	9.538AlaArg: 9.538 ± 0.079	7.289AlaSer: 7.289 ± 0.06	5.607AlaThr: 5.607 ± 0.059	8.48AlaVal: 8.48 ± 0.064	1.689AlaTrp: 1.689 ± 0.028	2.41AlaTyr: 2.41 ± 0.03	0.0AlaXaa: 0.0 ± 0.0
Cys	1.16CysAla: 1.16 ± 0.022	0.135CysCys: 0.135 ± 0.008	0.513CysAsp: 0.513 ± 0.017	0.573CysGlu: 0.573 ± 0.014	0.346CysPhe: 0.346 ± 0.011	1.074CysGly: 1.074 ± 0.028	0.27CysHis: 0.27 ± 0.012	0.311CysIle: 0.311 ± 0.011	0.219CysLys: 0.219 ± 0.009	0.95CysLeu: 0.95 ± 0.02	0.168CysMet: 0.168 ± 0.007	0.27CysAsn: 0.27 ± 0.012	0.618CysPro: 0.618 ± 0.019	0.367CysGln: 0.367 ± 0.013	0.677CysArg: 0.677 ± 0.018	0.623CysSer: 0.623 ± 0.019	0.592CysThr: 0.592 ± 0.016	0.701CysVal: 0.701 ± 0.016	0.147CysTrp: 0.147 ± 0.008	0.221CysTyr: 0.221 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.99AspAla: 5.99 ± 0.054	0.448AspCys: 0.448 ± 0.014	2.116AspAsp: 2.116 ± 0.036	3.057AspGlu: 3.057 ± 0.035	1.978AspPhe: 1.978 ± 0.027	4.611AspGly: 4.611 ± 0.065	0.821AspHis: 0.821 ± 0.017	1.806AspIle: 1.806 ± 0.027	1.293AspLys: 1.293 ± 0.024	4.799AspLeu: 4.799 ± 0.048	0.85AspMet: 0.85 ± 0.016	1.051AspAsn: 1.051 ± 0.024	2.983AspPro: 2.983 ± 0.042	1.289AspGln: 1.289 ± 0.025	3.14AspArg: 3.14 ± 0.034	2.428AspSer: 2.428 ± 0.032	2.586AspThr: 2.586 ± 0.046	3.902AspVal: 3.902 ± 0.038	0.75AspTrp: 0.75 ± 0.017	1.106AspTyr: 1.106 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	8.9GluAla: 8.9 ± 0.096	0.488GluCys: 0.488 ± 0.018	3.06GluAsp: 3.06 ± 0.037	4.586GluGlu: 4.586 ± 0.065	1.724GluPhe: 1.724 ± 0.027	5.771GluGly: 5.771 ± 0.051	1.464GluHis: 1.464 ± 0.024	1.851GluIle: 1.851 ± 0.025	2.229GluLys: 2.229 ± 0.035	7.114GluLeu: 7.114 ± 0.064	1.225GluMet: 1.225 ± 0.022	1.301GluAsn: 1.301 ± 0.022	3.703GluPro: 3.703 ± 0.037	2.769GluGln: 2.769 ± 0.032	6.002GluArg: 6.002 ± 0.062	2.9GluSer: 2.9 ± 0.03	2.997GluThr: 2.997 ± 0.036	5.247GluVal: 5.247 ± 0.047	0.793GluTrp: 0.793 ± 0.014	1.101GluTyr: 1.101 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.391PheAla: 3.391 ± 0.036	0.368PheCys: 0.368 ± 0.011	1.936PheAsp: 1.936 ± 0.027	2.286PheGlu: 2.286 ± 0.028	1.437PhePhe: 1.437 ± 0.027	2.811PheGly: 2.811 ± 0.034	0.805PheHis: 0.805 ± 0.015	1.302PheIle: 1.302 ± 0.021	0.934PheLys: 0.934 ± 0.015	3.608PheLeu: 3.608 ± 0.037	0.594PheMet: 0.594 ± 0.016	0.927PheAsn: 0.927 ± 0.02	1.712PhePro: 1.712 ± 0.025	1.389PheGln: 1.389 ± 0.019	2.314PheArg: 2.314 ± 0.027	2.372PheSer: 2.372 ± 0.033	2.19PheThr: 2.19 ± 0.042	2.43PheVal: 2.43 ± 0.03	0.449PheTrp: 0.449 ± 0.013	0.822PheTyr: 0.822 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	9.158GlyAla: 9.158 ± 0.058	1.052GlyCys: 1.052 ± 0.022	3.876GlyAsp: 3.876 ± 0.042	5.344GlyGlu: 5.344 ± 0.049	3.104GlyPhe: 3.104 ± 0.035	7.896GlyGly: 7.896 ± 0.078	1.939GlyHis: 1.939 ± 0.031	3.139GlyIle: 3.139 ± 0.033	3.198GlyLys: 3.198 ± 0.045	9.086GlyLeu: 9.086 ± 0.072	1.99GlyMet: 1.99 ± 0.025	2.268GlyAsn: 2.268 ± 0.037	4.389GlyPro: 4.389 ± 0.046	3.517GlyGln: 3.517 ± 0.041	6.352GlyArg: 6.352 ± 0.05	5.117GlySer: 5.117 ± 0.052	5.747GlyThr: 5.747 ± 0.082	6.443GlyVal: 6.443 ± 0.055	1.37GlyTrp: 1.37 ± 0.022	2.07GlyTyr: 2.07 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.386HisAla: 2.386 ± 0.03	0.231HisCys: 0.231 ± 0.01	0.877HisAsp: 0.877 ± 0.017	1.286HisGlu: 1.286 ± 0.022	0.868HisPhe: 0.868 ± 0.018	1.976HisGly: 1.976 ± 0.026	0.631HisHis: 0.631 ± 0.017	0.668HisIle: 0.668 ± 0.014	0.436HisLys: 0.436 ± 0.012	2.552HisLeu: 2.552 ± 0.036	0.349HisMet: 0.349 ± 0.011	0.412HisAsn: 0.412 ± 0.012	1.794HisPro: 1.794 ± 0.029	0.761HisGln: 0.761 ± 0.017	1.79HisArg: 1.79 ± 0.023	1.094HisSer: 1.094 ± 0.02	0.994HisThr: 0.994 ± 0.019	1.627HisVal: 1.627 ± 0.025	0.346HisTrp: 0.346 ± 0.011	0.565HisTyr: 0.565 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.71IleAla: 3.71 ± 0.04	0.321IleCys: 0.321 ± 0.011	1.926IleAsp: 1.926 ± 0.03	2.213IleGlu: 2.213 ± 0.029	1.02IlePhe: 1.02 ± 0.019	2.531IleGly: 2.531 ± 0.034	0.901IleHis: 0.901 ± 0.018	1.262IleIle: 1.262 ± 0.022	0.83IleLys: 0.83 ± 0.02	2.999IleLeu: 2.999 ± 0.036	0.366IleMet: 0.366 ± 0.01	0.945IleAsn: 0.945 ± 0.021	2.021IlePro: 2.021 ± 0.03	1.374IleGln: 1.374 ± 0.022	2.359IleArg: 2.359 ± 0.029	2.051IleSer: 2.051 ± 0.027	1.88IleThr: 1.88 ± 0.028	2.267IleVal: 2.267 ± 0.029	0.365IleTrp: 0.365 ± 0.012	0.716IleTyr: 0.716 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	3.709LysAla: 3.709 ± 0.05	0.209LysCys: 0.209 ± 0.009	1.796LysAsp: 1.796 ± 0.033	1.885LysGlu: 1.885 ± 0.035	0.701LysPhe: 0.701 ± 0.015	2.622LysGly: 2.622 ± 0.034	0.608LysHis: 0.608 ± 0.014	0.926LysIle: 0.926 ± 0.018	1.368LysLys: 1.368 ± 0.033	3.212LysLeu: 3.212 ± 0.038	0.616LysMet: 0.616 ± 0.016	0.809LysAsn: 0.809 ± 0.021	2.074LysPro: 2.074 ± 0.029	1.09LysGln: 1.09 ± 0.022	2.266LysArg: 2.266 ± 0.034	1.478LysSer: 1.478 ± 0.025	1.709LysThr: 1.709 ± 0.026	2.553LysVal: 2.553 ± 0.036	0.324LysTrp: 0.324 ± 0.01	0.597LysTyr: 0.597 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	13.494LeuAla: 13.494 ± 0.095	1.105LeuCys: 1.105 ± 0.021	5.336LeuAsp: 5.336 ± 0.048	7.639LeuGlu: 7.639 ± 0.072	3.643LeuPhe: 3.643 ± 0.04	9.387LeuGly: 9.387 ± 0.072	2.341LeuHis: 2.341 ± 0.029	3.322LeuIle: 3.322 ± 0.038	3.811LeuLys: 3.811 ± 0.041	12.079LeuLeu: 12.079 ± 0.1	1.984LeuMet: 1.984 ± 0.027	2.441LeuAsn: 2.441 ± 0.03	6.759LeuPro: 6.759 ± 0.061	3.722LeuGln: 3.722 ± 0.042	8.629LeuArg: 8.629 ± 0.071	7.631LeuSer: 7.631 ± 0.068	6.049LeuThr: 6.049 ± 0.047	7.924LeuVal: 7.924 ± 0.063	1.388LeuTrp: 1.388 ± 0.024	2.365LeuTyr: 2.365 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.361MetAla: 2.361 ± 0.027	0.137MetCys: 0.137 ± 0.007	0.991MetAsp: 0.991 ± 0.016	1.199MetGlu: 1.199 ± 0.022	0.461MetPhe: 0.461 ± 0.012	1.72MetGly: 1.72 ± 0.025	0.371MetHis: 0.371 ± 0.01	0.497MetIle: 0.497 ± 0.013	0.829MetLys: 0.829 ± 0.015	1.987MetLeu: 1.987 ± 0.024	0.418MetMet: 0.418 ± 0.013	0.562MetAsn: 0.562 ± 0.013	1.208MetPro: 1.208 ± 0.023	0.604MetGln: 0.604 ± 0.016	1.579MetArg: 1.579 ± 0.021	1.319MetSer: 1.319 ± 0.022	1.106MetThr: 1.106 ± 0.017	1.363MetVal: 1.363 ± 0.022	0.179MetTrp: 0.179 ± 0.008	0.274MetTyr: 0.274 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.695AsnAla: 2.695 ± 0.032	0.251AsnCys: 0.251 ± 0.01	1.079AsnAsp: 1.079 ± 0.043	1.186AsnGlu: 1.186 ± 0.024	0.775AsnPhe: 0.775 ± 0.018	2.258AsnGly: 2.258 ± 0.048	0.497AsnHis: 0.497 ± 0.012	0.937AsnIle: 0.937 ± 0.019	0.585AsnLys: 0.585 ± 0.015	2.487AsnLeu: 2.487 ± 0.032	0.361AsnMet: 0.361 ± 0.011	0.7AsnAsn: 0.7 ± 0.021	1.817AsnPro: 1.817 ± 0.031	0.793AsnGln: 0.793 ± 0.018	1.503AsnArg: 1.503 ± 0.025	1.167AsnSer: 1.167 ± 0.024	1.425AsnThr: 1.425 ± 0.038	1.806AsnVal: 1.806 ± 0.028	0.33AsnTrp: 0.33 ± 0.01	0.594AsnTyr: 0.594 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	6.925ProAla: 6.925 ± 0.064	0.468ProCys: 0.468 ± 0.013	3.0ProAsp: 3.0 ± 0.037	5.062ProGlu: 5.062 ± 0.053	1.982ProPhe: 1.982 ± 0.025	5.901ProGly: 5.901 ± 0.063	1.206ProHis: 1.206 ± 0.022	1.631ProIle: 1.631 ± 0.027	1.636ProLys: 1.636 ± 0.028	6.374ProLeu: 6.374 ± 0.058	1.297ProMet: 1.297 ± 0.021	1.264ProAsn: 1.264 ± 0.024	5.246ProPro: 5.246 ± 0.071	2.129ProGln: 2.129 ± 0.028	4.091ProArg: 4.091 ± 0.044	4.475ProSer: 4.475 ± 0.043	3.028ProThr: 3.028 ± 0.034	4.714ProVal: 4.714 ± 0.05	0.886ProTrp: 0.886 ± 0.02	1.17ProTyr: 1.17 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.882GlnAla: 4.882 ± 0.052	0.327GlnCys: 0.327 ± 0.012	1.7GlnAsp: 1.7 ± 0.024	2.547GlnGlu: 2.547 ± 0.029	1.002GlnPhe: 1.002 ± 0.018	3.611GlnGly: 3.611 ± 0.036	0.756GlnHis: 0.756 ± 0.017	1.057GlnIle: 1.057 ± 0.019	1.232GlnLys: 1.232 ± 0.021	3.81GlnLeu: 3.81 ± 0.041	0.702GlnMet: 0.702 ± 0.016	0.784GlnAsn: 0.784 ± 0.017	2.234GlnPro: 2.234 ± 0.032	1.596GlnGln: 1.596 ± 0.027	3.153GlnArg: 3.153 ± 0.033	1.863GlnSer: 1.863 ± 0.026	1.719GlnThr: 1.719 ± 0.029	3.29GlnVal: 3.29 ± 0.037	0.549GlnTrp: 0.549 ± 0.014	0.715GlnTyr: 0.715 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	8.503ArgAla: 8.503 ± 0.073	0.719ArgCys: 0.719 ± 0.017	3.275ArgAsp: 3.275 ± 0.033	5.451ArgGlu: 5.451 ± 0.05	3.032ArgPhe: 3.032 ± 0.031	5.508ArgGly: 5.508 ± 0.054	1.721ArgHis: 1.721 ± 0.026	3.043ArgIle: 3.043 ± 0.039	2.365ArgLys: 2.365 ± 0.036	9.075ArgLeu: 9.075 ± 0.083	1.9ArgMet: 1.9 ± 0.025	1.591ArgAsn: 1.591 ± 0.023	4.237ArgPro: 4.237 ± 0.05	2.955ArgGln: 2.955 ± 0.035	6.105ArgArg: 6.105 ± 0.064	4.035ArgSer: 4.035 ± 0.035	3.936ArgThr: 3.936 ± 0.036	5.966ArgVal: 5.966 ± 0.053	1.289ArgTrp: 1.289 ± 0.022	1.936ArgTyr: 1.936 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.781SerAla: 6.781 ± 0.054	0.6SerCys: 0.6 ± 0.019	2.604SerAsp: 2.604 ± 0.039	3.332SerGlu: 3.332 ± 0.037	2.296SerPhe: 2.296 ± 0.029	5.8SerGly: 5.8 ± 0.053	1.261SerHis: 1.261 ± 0.022	2.003SerIle: 2.003 ± 0.03	1.546SerLys: 1.546 ± 0.025	6.725SerLeu: 6.725 ± 0.062	1.128SerMet: 1.128 ± 0.019	1.449SerAsn: 1.449 ± 0.028	4.175SerPro: 4.175 ± 0.045	2.25SerGln: 2.25 ± 0.03	4.391SerArg: 4.391 ± 0.042	4.06SerSer: 4.06 ± 0.051	3.307SerThr: 3.307 ± 0.041	4.274SerVal: 4.274 ± 0.041	0.864SerTrp: 0.864 ± 0.02	1.287SerTyr: 1.287 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.997ThrAla: 5.997 ± 0.067	0.596ThrCys: 0.596 ± 0.019	2.37ThrAsp: 2.37 ± 0.037	2.786ThrGlu: 2.786 ± 0.034	2.064ThrPhe: 2.064 ± 0.031	5.209ThrGly: 5.209 ± 0.049	1.212ThrHis: 1.212 ± 0.02	1.407ThrIle: 1.407 ± 0.027	1.148ThrLys: 1.148 ± 0.025	6.7ThrLeu: 6.7 ± 0.056	0.744ThrMet: 0.744 ± 0.018	1.185ThrAsn: 1.185 ± 0.028	4.064ThrPro: 4.064 ± 0.051	2.073ThrGln: 2.073 ± 0.031	3.701ThrArg: 3.701 ± 0.034	3.24ThrSer: 3.24 ± 0.042	2.633ThrThr: 2.633 ± 0.053	4.708ThrVal: 4.708 ± 0.081	0.845ThrTrp: 0.845 ± 0.019	1.392ThrTyr: 1.392 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	8.468ValAla: 8.468 ± 0.065	0.766ValCys: 0.766 ± 0.017	4.088ValAsp: 4.088 ± 0.04	5.135ValGlu: 5.135 ± 0.05	2.431ValPhe: 2.431 ± 0.035	5.938ValGly: 5.938 ± 0.046	1.599ValHis: 1.599 ± 0.022	2.35ValIle: 2.35 ± 0.032	2.536ValLys: 2.536 ± 0.036	8.906ValLeu: 8.906 ± 0.065	1.441ValMet: 1.441 ± 0.021	1.883ValAsn: 1.883 ± 0.035	4.586ValPro: 4.586 ± 0.041	2.616ValGln: 2.616 ± 0.038	5.984ValArg: 5.984 ± 0.049	4.848ValSer: 4.848 ± 0.042	4.438ValThr: 4.438 ± 0.071	5.85ValVal: 5.85 ± 0.055	0.915ValTrp: 0.915 ± 0.022	1.551ValTyr: 1.551 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.39TrpAla: 1.39 ± 0.025	0.149TrpCys: 0.149 ± 0.008	0.659TrpAsp: 0.659 ± 0.016	0.824TrpGlu: 0.824 ± 0.019	0.42TrpPhe: 0.42 ± 0.013	1.127TrpGly: 1.127 ± 0.026	0.305TrpHis: 0.305 ± 0.01	0.416TrpIle: 0.416 ± 0.012	0.576TrpLys: 0.576 ± 0.016	1.604TrpLeu: 1.604 ± 0.028	0.393TrpMet: 0.393 ± 0.013	0.476TrpAsn: 0.476 ± 0.013	0.656TrpPro: 0.656 ± 0.016	0.502TrpGln: 0.502 ± 0.015	1.212TrpArg: 1.212 ± 0.021	0.897TrpSer: 0.897 ± 0.021	0.826TrpThr: 0.826 ± 0.018	1.11TrpVal: 1.11 ± 0.019	0.23TrpTrp: 0.23 ± 0.01	0.282TrpTyr: 0.282 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.322TyrAla: 2.322 ± 0.034	0.227TyrCys: 0.227 ± 0.009	1.129TyrAsp: 1.129 ± 0.021	1.332TyrGlu: 1.332 ± 0.025	0.873TyrPhe: 0.873 ± 0.018	1.972TyrGly: 1.972 ± 0.031	0.457TyrHis: 0.457 ± 0.013	0.635TyrIle: 0.635 ± 0.016	0.553TyrLys: 0.553 ± 0.015	2.358TyrLeu: 2.358 ± 0.03	0.362TyrMet: 0.362 ± 0.011	0.564TyrAsn: 0.564 ± 0.016	1.138TyrPro: 1.138 ± 0.024	0.826TyrGln: 0.826 ± 0.019	1.854TyrArg: 1.854 ± 0.03	1.244TyrSer: 1.244 ± 0.026	1.308TyrThr: 1.308 ± 0.028	1.673TyrVal: 1.673 ± 0.026	0.347TyrTrp: 0.347 ± 0.012	0.573TyrTyr: 0.573 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8307 proteins (3100399 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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