Amino acid dipepetide frequency for Chitinophaga lutea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.187AlaAla: 10.187 ± 0.121	0.9AlaCys: 0.9 ± 0.024	4.876AlaAsp: 4.876 ± 0.055	4.73AlaGlu: 4.73 ± 0.053	3.879AlaPhe: 3.879 ± 0.049	7.825AlaGly: 7.825 ± 0.096	1.482AlaHis: 1.482 ± 0.029	5.015AlaIle: 5.015 ± 0.058	4.123AlaLys: 4.123 ± 0.054	8.119AlaLeu: 8.119 ± 0.078	2.172AlaMet: 2.172 ± 0.039	3.52AlaAsn: 3.52 ± 0.06	3.563AlaPro: 3.563 ± 0.065	3.414AlaGln: 3.414 ± 0.041	3.976AlaArg: 3.976 ± 0.054	4.699AlaSer: 4.699 ± 0.065	4.862AlaThr: 4.862 ± 0.103	6.238AlaVal: 6.238 ± 0.074	1.114AlaTrp: 1.114 ± 0.023	3.294AlaTyr: 3.294 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.611CysAla: 0.611 ± 0.024	0.163CysCys: 0.163 ± 0.01	0.357CysAsp: 0.357 ± 0.015	0.393CysGlu: 0.393 ± 0.015	0.415CysPhe: 0.415 ± 0.017	0.692CysGly: 0.692 ± 0.02	0.191CysHis: 0.191 ± 0.012	0.581CysIle: 0.581 ± 0.018	0.429CysLys: 0.429 ± 0.017	0.823CysLeu: 0.823 ± 0.019	0.229CysMet: 0.229 ± 0.011	0.393CysAsn: 0.393 ± 0.017	0.338CysPro: 0.338 ± 0.014	0.215CysGln: 0.215 ± 0.01	0.454CysArg: 0.454 ± 0.015	0.495CysSer: 0.495 ± 0.018	0.487CysThr: 0.487 ± 0.017	0.473CysVal: 0.473 ± 0.016	0.124CysTrp: 0.124 ± 0.009	0.336CysTyr: 0.336 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.578AspAla: 4.578 ± 0.056	0.351AspCys: 0.351 ± 0.015	2.332AspAsp: 2.332 ± 0.048	3.057AspGlu: 3.057 ± 0.053	2.596AspPhe: 2.596 ± 0.039	4.019AspGly: 4.019 ± 0.052	0.972AspHis: 0.972 ± 0.025	3.477AspIle: 3.477 ± 0.049	3.107AspLys: 3.107 ± 0.047	4.351AspLeu: 4.351 ± 0.049	1.224AspMet: 1.224 ± 0.026	2.432AspAsn: 2.432 ± 0.043	2.287AspPro: 2.287 ± 0.037	1.61AspGln: 1.61 ± 0.031	2.425AspArg: 2.425 ± 0.038	2.756AspSer: 2.756 ± 0.045	2.611AspThr: 2.611 ± 0.042	3.592AspVal: 3.592 ± 0.038	0.779AspTrp: 0.779 ± 0.019	2.337AspTyr: 2.337 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.855GluAla: 4.855 ± 0.056	0.346GluCys: 0.346 ± 0.017	2.466GluAsp: 2.466 ± 0.038	3.665GluGlu: 3.665 ± 0.066	2.132GluPhe: 2.132 ± 0.036	3.677GluGly: 3.677 ± 0.046	1.143GluHis: 1.143 ± 0.029	3.409GluIle: 3.409 ± 0.047	4.482GluLys: 4.482 ± 0.065	5.359GluLeu: 5.359 ± 0.061	1.574GluMet: 1.574 ± 0.03	2.849GluAsn: 2.849 ± 0.048	1.89GluPro: 1.89 ± 0.034	2.537GluGln: 2.537 ± 0.044	2.745GluArg: 2.745 ± 0.046	2.472GluSer: 2.472 ± 0.038	2.953GluThr: 2.953 ± 0.042	3.719GluVal: 3.719 ± 0.046	0.744GluTrp: 0.744 ± 0.02	1.98GluTyr: 1.98 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.44PheAla: 3.44 ± 0.047	0.432PheCys: 0.432 ± 0.015	2.613PheAsp: 2.613 ± 0.043	2.413PheGlu: 2.413 ± 0.038	2.339PhePhe: 2.339 ± 0.042	3.378PheGly: 3.378 ± 0.043	0.918PheHis: 0.918 ± 0.021	2.824PheIle: 2.824 ± 0.048	2.225PheLys: 2.225 ± 0.036	4.069PheLeu: 4.069 ± 0.058	1.199PheMet: 1.199 ± 0.028	2.554PheAsn: 2.554 ± 0.038	1.899PhePro: 1.899 ± 0.032	1.385PheGln: 1.385 ± 0.025	2.658PheArg: 2.658 ± 0.035	3.511PheSer: 3.511 ± 0.05	3.222PheThr: 3.222 ± 0.045	2.751PheVal: 2.751 ± 0.045	0.603PheTrp: 0.603 ± 0.017	1.904PheTyr: 1.904 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	5.976GlyAla: 5.976 ± 0.082	0.659GlyCys: 0.659 ± 0.024	3.532GlyAsp: 3.532 ± 0.049	3.764GlyGlu: 3.764 ± 0.042	3.626GlyPhe: 3.626 ± 0.046	5.827GlyGly: 5.827 ± 0.084	1.447GlyHis: 1.447 ± 0.03	5.093GlyIle: 5.093 ± 0.06	5.107GlyLys: 5.107 ± 0.057	6.557GlyLeu: 6.557 ± 0.065	1.985GlyMet: 1.985 ± 0.034	4.006GlyAsn: 4.006 ± 0.061	2.004GlyPro: 2.004 ± 0.037	2.687GlyGln: 2.687 ± 0.045	3.691GlyArg: 3.691 ± 0.049	4.458GlySer: 4.458 ± 0.06	4.742GlyThr: 4.742 ± 0.097	4.96GlyVal: 4.96 ± 0.065	1.158GlyTrp: 1.158 ± 0.029	3.321GlyTyr: 3.321 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.589HisAla: 1.589 ± 0.03	0.226HisCys: 0.226 ± 0.01	0.936HisAsp: 0.936 ± 0.027	1.042HisGlu: 1.042 ± 0.021	1.174HisPhe: 1.174 ± 0.024	1.272HisGly: 1.272 ± 0.029	0.635HisHis: 0.635 ± 0.018	1.37HisIle: 1.37 ± 0.029	0.922HisLys: 0.922 ± 0.025	2.071HisLeu: 2.071 ± 0.038	0.439HisMet: 0.439 ± 0.015	0.914HisAsn: 0.914 ± 0.021	1.245HisPro: 1.245 ± 0.028	0.805HisGln: 0.805 ± 0.02	1.085HisArg: 1.085 ± 0.028	1.058HisSer: 1.058 ± 0.025	1.183HisThr: 1.183 ± 0.024	1.117HisVal: 1.117 ± 0.027	0.31HisTrp: 0.31 ± 0.012	0.912HisTyr: 0.912 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.44IleAla: 5.44 ± 0.058	0.647IleCys: 0.647 ± 0.02	3.277IleAsp: 3.277 ± 0.043	3.066IleGlu: 3.066 ± 0.046	2.63IlePhe: 2.63 ± 0.046	4.35IleGly: 4.35 ± 0.054	1.215IleHis: 1.215 ± 0.023	3.552IleIle: 3.552 ± 0.057	3.109IleLys: 3.109 ± 0.047	5.146IleLeu: 5.146 ± 0.061	1.25IleMet: 1.25 ± 0.029	2.956IleAsn: 2.956 ± 0.043	3.021IlePro: 3.021 ± 0.042	1.948IleGln: 1.948 ± 0.03	3.68IleArg: 3.68 ± 0.049	4.126IleSer: 4.126 ± 0.042	4.203IleThr: 4.203 ± 0.074	3.781IleVal: 3.781 ± 0.051	0.712IleTrp: 0.712 ± 0.023	2.157IleTyr: 2.157 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	5.071LysAla: 5.071 ± 0.076	0.285LysCys: 0.285 ± 0.013	3.506LysAsp: 3.506 ± 0.043	3.853LysGlu: 3.853 ± 0.052	1.937LysPhe: 1.937 ± 0.034	4.366LysGly: 4.366 ± 0.059	1.126LysHis: 1.126 ± 0.027	3.416LysIle: 3.416 ± 0.054	4.342LysLys: 4.342 ± 0.066	4.842LysLeu: 4.842 ± 0.057	1.7LysMet: 1.7 ± 0.032	2.996LysAsn: 2.996 ± 0.044	2.634LysPro: 2.634 ± 0.043	2.338LysGln: 2.338 ± 0.04	2.622LysArg: 2.622 ± 0.037	2.875LysSer: 2.875 ± 0.039	3.572LysThr: 3.572 ± 0.044	3.888LysVal: 3.888 ± 0.044	0.739LysTrp: 0.739 ± 0.019	2.191LysTyr: 2.191 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	7.865LeuAla: 7.865 ± 0.089	0.871LeuCys: 0.871 ± 0.024	4.48LeuAsp: 4.48 ± 0.053	5.12LeuGlu: 5.12 ± 0.062	4.286LeuPhe: 4.286 ± 0.054	6.112LeuGly: 6.112 ± 0.064	2.149LeuHis: 2.149 ± 0.038	5.066LeuIle: 5.066 ± 0.061	5.759LeuLys: 5.759 ± 0.058	10.089LeuLeu: 10.089 ± 0.112	2.244LeuMet: 2.244 ± 0.035	4.475LeuAsn: 4.475 ± 0.054	4.745LeuPro: 4.745 ± 0.057	4.731LeuGln: 4.731 ± 0.066	4.966LeuArg: 4.966 ± 0.061	6.067LeuSer: 6.067 ± 0.057	5.425LeuThr: 5.425 ± 0.071	5.631LeuVal: 5.631 ± 0.06	1.014LeuTrp: 1.014 ± 0.027	3.37LeuTyr: 3.37 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.173MetAla: 2.173 ± 0.037	0.147MetCys: 0.147 ± 0.009	1.242MetAsp: 1.242 ± 0.025	1.546MetGlu: 1.546 ± 0.03	0.834MetPhe: 0.834 ± 0.022	1.643MetGly: 1.643 ± 0.033	0.548MetHis: 0.548 ± 0.017	1.341MetIle: 1.341 ± 0.027	1.95MetLys: 1.95 ± 0.038	2.463MetLeu: 2.463 ± 0.037	0.687MetMet: 0.687 ± 0.019	1.206MetAsn: 1.206 ± 0.027	1.283MetPro: 1.283 ± 0.027	1.304MetGln: 1.304 ± 0.03	1.291MetArg: 1.291 ± 0.025	1.255MetSer: 1.255 ± 0.024	1.236MetThr: 1.236 ± 0.027	1.482MetVal: 1.482 ± 0.025	0.242MetTrp: 0.242 ± 0.011	0.747MetTyr: 0.747 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	4.051AsnAla: 4.051 ± 0.063	0.356AsnCys: 0.356 ± 0.017	2.414AsnAsp: 2.414 ± 0.04	2.408AsnGlu: 2.408 ± 0.032	2.163AsnPhe: 2.163 ± 0.039	4.219AsnGly: 4.219 ± 0.071	0.846AsnHis: 0.846 ± 0.024	3.477AsnIle: 3.477 ± 0.057	2.589AsnLys: 2.589 ± 0.038	4.032AsnLeu: 4.032 ± 0.048	1.169AsnMet: 1.169 ± 0.024	2.657AsnAsn: 2.657 ± 0.047	2.599AsnPro: 2.599 ± 0.04	1.529AsnGln: 1.529 ± 0.027	2.581AsnArg: 2.581 ± 0.041	2.626AsnSer: 2.626 ± 0.04	3.098AsnThr: 3.098 ± 0.049	3.116AsnVal: 3.116 ± 0.05	0.702AsnTrp: 0.702 ± 0.021	2.084AsnTyr: 2.084 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	5.234ProAla: 5.234 ± 0.081	0.258ProCys: 0.258 ± 0.013	2.907ProAsp: 2.907 ± 0.039	3.023ProGlu: 3.023 ± 0.044	2.035ProPhe: 2.035 ± 0.033	3.924ProGly: 3.924 ± 0.05	0.847ProHis: 0.847 ± 0.022	1.883ProIle: 1.883 ± 0.034	1.938ProLys: 1.938 ± 0.037	3.863ProLeu: 3.863 ± 0.042	0.903ProMet: 0.903 ± 0.022	1.731ProAsn: 1.731 ± 0.034	1.626ProPro: 1.626 ± 0.036	1.691ProGln: 1.691 ± 0.031	1.686ProArg: 1.686 ± 0.035	2.333ProSer: 2.333 ± 0.034	1.85ProThr: 1.85 ± 0.035	4.136ProVal: 4.136 ± 0.058	0.543ProTrp: 0.543 ± 0.016	1.685ProTyr: 1.685 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.252GlnAla: 3.252 ± 0.041	0.245GlnCys: 0.245 ± 0.013	1.588GlnAsp: 1.588 ± 0.03	2.193GlnGlu: 2.193 ± 0.036	1.755GlnPhe: 1.755 ± 0.03	2.313GlnGly: 2.313 ± 0.036	1.098GlnHis: 1.098 ± 0.027	1.996GlnIle: 1.996 ± 0.032	2.155GlnLys: 2.155 ± 0.034	4.561GlnLeu: 4.561 ± 0.061	0.942GlnMet: 0.942 ± 0.021	1.673GlnAsn: 1.673 ± 0.029	2.109GlnPro: 2.109 ± 0.041	2.768GlnGln: 2.768 ± 0.047	2.075GlnArg: 2.075 ± 0.035	2.005GlnSer: 2.005 ± 0.034	2.137GlnThr: 2.137 ± 0.035	2.632GlnVal: 2.632 ± 0.037	0.589GlnTrp: 0.589 ± 0.017	1.736GlnTyr: 1.736 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	3.353ArgAla: 3.353 ± 0.045	0.33ArgCys: 0.33 ± 0.014	2.369ArgAsp: 2.369 ± 0.037	3.13ArgGlu: 3.13 ± 0.044	2.726ArgPhe: 2.726 ± 0.042	2.819ArgGly: 2.819 ± 0.043	1.17ArgHis: 1.17 ± 0.027	3.472ArgIle: 3.472 ± 0.04	3.336ArgLys: 3.336 ± 0.046	5.129ArgLeu: 5.129 ± 0.056	1.44ArgMet: 1.44 ± 0.027	2.742ArgAsn: 2.742 ± 0.04	1.973ArgPro: 1.973 ± 0.032	2.398ArgGln: 2.398 ± 0.036	2.592ArgArg: 2.592 ± 0.041	2.671ArgSer: 2.671 ± 0.038	2.557ArgThr: 2.557 ± 0.039	3.021ArgVal: 3.021 ± 0.038	0.833ArgTrp: 0.833 ± 0.021	2.378ArgTyr: 2.378 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	4.99SerAla: 4.99 ± 0.056	0.524SerCys: 0.524 ± 0.016	2.622SerAsp: 2.622 ± 0.035	2.569SerGlu: 2.569 ± 0.041	3.173SerPhe: 3.173 ± 0.043	4.984SerGly: 4.984 ± 0.065	1.068SerHis: 1.068 ± 0.028	3.643SerIle: 3.643 ± 0.046	2.767SerLys: 2.767 ± 0.04	5.761SerLeu: 5.761 ± 0.056	1.368SerMet: 1.368 ± 0.026	2.568SerAsn: 2.568 ± 0.043	2.516SerPro: 2.516 ± 0.038	1.8SerGln: 1.8 ± 0.03	3.018SerArg: 3.018 ± 0.042	3.389SerSer: 3.389 ± 0.057	3.277SerThr: 3.277 ± 0.048	3.933SerVal: 3.933 ± 0.052	0.867SerTrp: 0.867 ± 0.024	2.35SerTyr: 2.35 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.918ThrAla: 5.918 ± 0.105	0.377ThrCys: 0.377 ± 0.014	3.29ThrAsp: 3.29 ± 0.049	2.758ThrGlu: 2.758 ± 0.037	2.718ThrPhe: 2.718 ± 0.039	5.639ThrGly: 5.639 ± 0.071	1.029ThrHis: 1.029 ± 0.022	3.603ThrIle: 3.603 ± 0.069	2.497ThrLys: 2.497 ± 0.038	5.504ThrLeu: 5.504 ± 0.065	1.148ThrMet: 1.148 ± 0.024	2.449ThrAsn: 2.449 ± 0.061	3.034ThrPro: 3.034 ± 0.048	1.833ThrGln: 1.833 ± 0.029	2.596ThrArg: 2.596 ± 0.043	3.086ThrSer: 3.086 ± 0.042	3.483ThrThr: 3.483 ± 0.073	4.627ThrVal: 4.627 ± 0.099	0.816ThrTrp: 0.816 ± 0.026	2.264ThrTyr: 2.264 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	5.281ValAla: 5.281 ± 0.057	0.618ValCys: 0.618 ± 0.022	3.14ValAsp: 3.14 ± 0.039	3.483ValGlu: 3.483 ± 0.051	3.173ValPhe: 3.173 ± 0.045	3.696ValGly: 3.696 ± 0.048	1.279ValHis: 1.279 ± 0.029	4.217ValIle: 4.217 ± 0.053	4.381ValLys: 4.381 ± 0.056	6.54ValLeu: 6.54 ± 0.072	1.68ValMet: 1.68 ± 0.031	3.58ValAsn: 3.58 ± 0.064	3.112ValPro: 3.112 ± 0.043	2.635ValGln: 2.635 ± 0.036	3.2ValArg: 3.2 ± 0.041	4.259ValSer: 4.259 ± 0.054	4.494ValThr: 4.494 ± 0.103	4.479ValVal: 4.479 ± 0.06	0.808ValTrp: 0.808 ± 0.022	2.538ValTyr: 2.538 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	0.957TrpAla: 0.957 ± 0.024	0.132TrpCys: 0.132 ± 0.008	0.709TrpAsp: 0.709 ± 0.02	0.803TrpGlu: 0.803 ± 0.019	0.568TrpPhe: 0.568 ± 0.019	1.002TrpGly: 1.002 ± 0.023	0.301TrpHis: 0.301 ± 0.012	0.712TrpIle: 0.712 ± 0.019	0.89TrpLys: 0.89 ± 0.022	1.419TrpLeu: 1.419 ± 0.031	0.437TrpMet: 0.437 ± 0.016	0.734TrpAsn: 0.734 ± 0.019	0.447TrpPro: 0.447 ± 0.016	0.695TrpGln: 0.695 ± 0.017	0.7TrpArg: 0.7 ± 0.019	0.705TrpSer: 0.705 ± 0.022	0.726TrpThr: 0.726 ± 0.023	0.791TrpVal: 0.791 ± 0.021	0.267TrpTrp: 0.267 ± 0.013	0.561TrpTyr: 0.561 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.166TyrAla: 3.166 ± 0.043	0.335TyrCys: 0.335 ± 0.014	2.236TyrAsp: 2.236 ± 0.038	1.982TyrGlu: 1.982 ± 0.033	2.175TyrPhe: 2.175 ± 0.036	2.844TyrGly: 2.844 ± 0.044	0.844TyrHis: 0.844 ± 0.019	2.116TyrIle: 2.116 ± 0.035	2.192TyrLys: 2.192 ± 0.032	3.766TyrLeu: 3.766 ± 0.042	0.831TyrMet: 0.831 ± 0.019	2.28TyrAsn: 2.28 ± 0.044	1.769TyrPro: 1.769 ± 0.036	1.502TyrGln: 1.502 ± 0.027	2.396TyrArg: 2.396 ± 0.038	2.345TyrSer: 2.345 ± 0.037	2.549TyrThr: 2.549 ± 0.04	2.225TyrVal: 2.225 ± 0.036	0.59TyrTrp: 0.59 ± 0.019	1.811TyrTyr: 1.811 ± 0.035	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5334 proteins (1965502 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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