Amino acid dipepetide frequency for Hubei unio douglasiae virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.802AlaAla: 17.802 ± 1.501
0.774AlaCys: 0.774 ± 1.099
5.418AlaAsp: 5.418 ± 1.749
3.87AlaGlu: 3.87 ± 2.524
5.418AlaPhe: 5.418 ± 1.224
13.932AlaGly: 13.932 ± 1.023
3.096AlaHis: 3.096 ± 1.549
3.87AlaIle: 3.87 ± 1.936
5.418AlaLys: 5.418 ± 0.263
6.192AlaLeu: 6.192 ± 0.124
1.548AlaMet: 1.548 ± 0.712
3.87AlaAsn: 3.87 ± 1.037
3.096AlaPro: 3.096 ± 1.424
6.192AlaGln: 6.192 ± 1.362
9.288AlaArg: 9.288 ± 1.673
4.644AlaSer: 4.644 ± 2.137
5.418AlaThr: 5.418 ± 1.749
14.706AlaVal: 14.706 ± 2.897
5.418AlaTrp: 5.418 ± 1.224
6.966AlaTyr: 6.966 ± 0.511
0.0AlaXaa: 0.0 ± 0.0
Cys
1.548CysAla: 1.548 ± 0.774
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.322CysGly: 2.322 ± 1.161
0.774CysHis: 0.774 ± 1.099
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.774CysLeu: 0.774 ± 0.387
1.548CysMet: 1.548 ± 0.712
0.0CysAsn: 0.0 ± 0.0
0.774CysPro: 0.774 ± 0.387
0.774CysGln: 0.774 ± 0.387
0.0CysArg: 0.0 ± 0.0
0.774CysSer: 0.774 ± 0.387
0.0CysThr: 0.0 ± 0.0
3.096CysVal: 3.096 ± 0.062
0.0CysTrp: 0.0 ± 0.0
1.548CysTyr: 1.548 ± 0.712
0.0CysXaa: 0.0 ± 0.0
Asp
6.192AspAla: 6.192 ± 1.611
0.0AspCys: 0.0 ± 0.0
5.418AspAsp: 5.418 ± 0.263
2.322AspGlu: 2.322 ± 1.161
0.774AspPhe: 0.774 ± 0.387
5.418AspGly: 5.418 ± 1.224
0.0AspHis: 0.0 ± 0.0
2.322AspIle: 2.322 ± 0.325
0.0AspLys: 0.0 ± 0.0
3.87AspLeu: 3.87 ± 0.449
1.548AspMet: 1.548 ± 0.774
0.0AspAsn: 0.0 ± 0.0
5.418AspPro: 5.418 ± 1.749
0.0AspGln: 0.0 ± 0.0
3.096AspArg: 3.096 ± 1.424
3.096AspSer: 3.096 ± 1.549
6.192AspThr: 6.192 ± 3.097
2.322AspVal: 2.322 ± 1.812
0.774AspTrp: 0.774 ± 0.387
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.192GluAla: 6.192 ± 1.362
0.774GluCys: 0.774 ± 0.387
0.774GluAsp: 0.774 ± 0.387
1.548GluGlu: 1.548 ± 0.774
1.548GluPhe: 1.548 ± 0.774
3.096GluGly: 3.096 ± 1.549
0.0GluHis: 0.0 ± 0.0
0.774GluIle: 0.774 ± 0.387
1.548GluLys: 1.548 ± 0.774
6.966GluLeu: 6.966 ± 1.998
0.774GluMet: 0.774 ± 0.387
0.0GluAsn: 0.0 ± 0.0
2.322GluPro: 2.322 ± 1.161
3.096GluGln: 3.096 ± 0.062
0.774GluArg: 0.774 ± 0.387
3.87GluSer: 3.87 ± 0.449
3.096GluThr: 3.096 ± 0.062
2.322GluVal: 2.322 ± 0.325
1.548GluTrp: 1.548 ± 2.199
0.774GluTyr: 0.774 ± 0.387
0.0GluXaa: 0.0 ± 0.0
Phe
2.322PheAla: 2.322 ± 0.325
1.548PheCys: 1.548 ± 0.774
2.322PheAsp: 2.322 ± 0.325
2.322PheGlu: 2.322 ± 0.325
0.0PhePhe: 0.0 ± 0.0
2.322PheGly: 2.322 ± 1.812
0.0PheHis: 0.0 ± 0.0
1.548PheIle: 1.548 ± 0.712
0.0PheLys: 0.0 ± 0.0
3.096PheLeu: 3.096 ± 1.549
0.774PheMet: 0.774 ± 0.387
1.548PheAsn: 1.548 ± 0.774
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
0.774PheSer: 0.774 ± 0.387
2.322PheThr: 2.322 ± 1.161
5.418PheVal: 5.418 ± 1.749
0.774PheTrp: 0.774 ± 0.387
0.774PheTyr: 0.774 ± 0.387
0.0PheXaa: 0.0 ± 0.0
Gly
11.61GlyAla: 11.61 ± 1.625
0.774GlyCys: 0.774 ± 0.387
1.548GlyAsp: 1.548 ± 0.774
0.774GlyGlu: 0.774 ± 0.387
3.87GlyPhe: 3.87 ± 2.524
3.87GlyGly: 3.87 ± 1.037
0.0GlyHis: 0.0 ± 0.0
2.322GlyIle: 2.322 ± 1.812
6.966GlyLys: 6.966 ± 1.998
10.062GlyLeu: 10.062 ± 3.547
1.548GlyMet: 1.548 ± 1.669
2.322GlyAsn: 2.322 ± 3.298
1.548GlyPro: 1.548 ± 0.712
0.774GlyGln: 0.774 ± 1.099
6.192GlyArg: 6.192 ± 2.849
6.192GlySer: 6.192 ± 1.362
2.322GlyThr: 2.322 ± 0.325
11.61GlyVal: 11.61 ± 3.112
1.548GlyTrp: 1.548 ± 0.774
3.87GlyTyr: 3.87 ± 1.037
0.0GlyXaa: 0.0 ± 0.0
His
2.322HisAla: 2.322 ± 1.161
0.0HisCys: 0.0 ± 0.0
1.548HisAsp: 1.548 ± 0.712
2.322HisGlu: 2.322 ± 1.161
0.0HisPhe: 0.0 ± 0.0
0.774HisGly: 0.774 ± 0.387
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.774HisLys: 0.774 ± 0.387
1.548HisLeu: 1.548 ± 0.712
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.096HisPro: 3.096 ± 0.062
0.0HisGln: 0.0 ± 0.0
1.548HisArg: 1.548 ± 0.774
0.774HisSer: 0.774 ± 0.387
1.548HisThr: 1.548 ± 0.774
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.418IleAla: 5.418 ± 2.71
0.774IleCys: 0.774 ± 0.387
2.322IleAsp: 2.322 ± 1.161
0.0IleGlu: 0.0 ± 0.0
1.548IlePhe: 1.548 ± 0.774
3.87IleGly: 3.87 ± 2.524
0.774IleHis: 0.774 ± 0.387
1.548IleIle: 1.548 ± 0.712
0.0IleLys: 0.0 ± 0.0
0.774IleLeu: 0.774 ± 0.387
1.548IleMet: 1.548 ± 0.774
1.548IleAsn: 1.548 ± 0.712
1.548IlePro: 1.548 ± 0.712
0.0IleGln: 0.0 ± 0.0
1.548IleArg: 1.548 ± 0.774
2.322IleSer: 2.322 ± 1.161
3.096IleThr: 3.096 ± 0.062
5.418IleVal: 5.418 ± 1.749
0.774IleTrp: 0.774 ± 0.387
0.774IleTyr: 0.774 ± 0.387
0.0IleXaa: 0.0 ± 0.0
Lys
3.87LysAla: 3.87 ± 2.524
0.774LysCys: 0.774 ± 0.387
1.548LysAsp: 1.548 ± 0.774
2.322LysGlu: 2.322 ± 1.161
1.548LysPhe: 1.548 ± 0.774
2.322LysGly: 2.322 ± 1.812
0.0LysHis: 0.0 ± 0.0
2.322LysIle: 2.322 ± 1.161
1.548LysLys: 1.548 ± 0.774
3.87LysLeu: 3.87 ± 1.936
1.548LysMet: 1.548 ± 0.712
0.0LysAsn: 0.0 ± 0.0
2.322LysPro: 2.322 ± 1.161
1.548LysGln: 1.548 ± 0.712
3.87LysArg: 3.87 ± 1.936
1.548LysSer: 1.548 ± 0.774
1.548LysThr: 1.548 ± 0.774
3.096LysVal: 3.096 ± 1.549
0.774LysTrp: 0.774 ± 1.099
0.774LysTyr: 0.774 ± 0.387
0.0LysXaa: 0.0 ± 0.0
Leu
8.514LeuAla: 8.514 ± 1.687
3.096LeuCys: 3.096 ± 0.062
5.418LeuAsp: 5.418 ± 3.236
3.096LeuGlu: 3.096 ± 1.549
1.548LeuPhe: 1.548 ± 0.774
6.966LeuGly: 6.966 ± 0.511
3.096LeuHis: 3.096 ± 1.549
2.322LeuIle: 2.322 ± 1.161
3.87LeuLys: 3.87 ± 0.449
5.418LeuLeu: 5.418 ± 1.224
1.548LeuMet: 1.548 ± 0.712
3.096LeuAsn: 3.096 ± 1.424
6.192LeuPro: 6.192 ± 0.124
2.322LeuGln: 2.322 ± 1.161
5.418LeuArg: 5.418 ± 1.749
5.418LeuSer: 5.418 ± 1.749
2.322LeuThr: 2.322 ± 0.325
3.87LeuVal: 3.87 ± 0.449
1.548LeuTrp: 1.548 ± 0.774
0.774LeuTyr: 0.774 ± 0.387
0.0LeuXaa: 0.0 ± 0.0
Met
3.87MetAla: 3.87 ± 0.449
0.774MetCys: 0.774 ± 0.387
1.548MetAsp: 1.548 ± 0.774
0.774MetGlu: 0.774 ± 0.387
0.774MetPhe: 0.774 ± 0.387
2.322MetGly: 2.322 ± 1.812
0.774MetHis: 0.774 ± 0.387
0.774MetIle: 0.774 ± 0.387
0.0MetLys: 0.0 ± 0.0
2.322MetLeu: 2.322 ± 0.325
0.774MetMet: 0.774 ± 1.099
0.0MetAsn: 0.0 ± 0.0
2.322MetPro: 2.322 ± 1.812
2.322MetGln: 2.322 ± 0.325
0.774MetArg: 0.774 ± 0.387
1.548MetSer: 1.548 ± 0.712
1.548MetThr: 1.548 ± 0.774
1.548MetVal: 1.548 ± 0.774
0.0MetTrp: 0.0 ± 0.0
0.774MetTyr: 0.774 ± 0.387
0.0MetXaa: 0.0 ± 0.0
Asn
3.87AsnAla: 3.87 ± 0.449
0.0AsnCys: 0.0 ± 0.0
0.774AsnAsp: 0.774 ± 1.099
0.774AsnGlu: 0.774 ± 1.099
0.0AsnPhe: 0.0 ± 0.0
2.322AsnGly: 2.322 ± 3.298
0.0AsnHis: 0.0 ± 0.0
1.548AsnIle: 1.548 ± 0.774
0.0AsnLys: 0.0 ± 0.0
0.774AsnLeu: 0.774 ± 1.099
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
3.87AsnPro: 3.87 ± 1.936
1.548AsnGln: 1.548 ± 0.774
2.322AsnArg: 2.322 ± 1.812
0.774AsnSer: 0.774 ± 1.099
3.096AsnThr: 3.096 ± 2.911
2.322AsnVal: 2.322 ± 1.161
0.774AsnTrp: 0.774 ± 0.387
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.966ProAla: 6.966 ± 0.511
1.548ProCys: 1.548 ± 0.712
2.322ProAsp: 2.322 ± 1.161
3.87ProGlu: 3.87 ± 1.037
0.774ProPhe: 0.774 ± 1.099
6.192ProGly: 6.192 ± 2.849
1.548ProHis: 1.548 ± 0.774
2.322ProIle: 2.322 ± 1.161
3.87ProLys: 3.87 ± 0.449
5.418ProLeu: 5.418 ± 1.749
1.548ProMet: 1.548 ± 0.774
1.548ProAsn: 1.548 ± 0.774
4.644ProPro: 4.644 ± 0.65
2.322ProGln: 2.322 ± 1.161
6.966ProArg: 6.966 ± 0.511
3.096ProSer: 3.096 ± 0.062
3.096ProThr: 3.096 ± 0.062
5.418ProVal: 5.418 ± 0.263
1.548ProTrp: 1.548 ± 0.774
0.774ProTyr: 0.774 ± 0.387
0.0ProXaa: 0.0 ± 0.0
Gln
1.548GlnAla: 1.548 ± 0.774
0.774GlnCys: 0.774 ± 0.387
2.322GlnAsp: 2.322 ± 1.161
1.548GlnGlu: 1.548 ± 0.774
0.0GlnPhe: 0.0 ± 0.0
3.096GlnGly: 3.096 ± 2.911
0.774GlnHis: 0.774 ± 0.387
1.548GlnIle: 1.548 ± 0.774
0.774GlnLys: 0.774 ± 0.387
2.322GlnLeu: 2.322 ± 0.325
0.774GlnMet: 0.774 ± 0.387
0.0GlnAsn: 0.0 ± 0.0
0.774GlnPro: 0.774 ± 0.387
0.774GlnGln: 0.774 ± 0.387
5.418GlnArg: 5.418 ± 1.749
3.096GlnSer: 3.096 ± 1.424
0.774GlnThr: 0.774 ± 0.387
3.096GlnVal: 3.096 ± 0.062
1.548GlnTrp: 1.548 ± 0.712
0.774GlnTyr: 0.774 ± 0.387
0.0GlnXaa: 0.0 ± 0.0
Arg
6.966ArgAla: 6.966 ± 0.511
1.548ArgCys: 1.548 ± 0.712
3.096ArgAsp: 3.096 ± 1.549
2.322ArgGlu: 2.322 ± 1.161
3.87ArgPhe: 3.87 ± 1.037
3.87ArgGly: 3.87 ± 1.037
0.0ArgHis: 0.0 ± 0.0
1.548ArgIle: 1.548 ± 0.712
2.322ArgLys: 2.322 ± 0.325
4.644ArgLeu: 4.644 ± 0.65
2.322ArgMet: 2.322 ± 1.812
3.87ArgAsn: 3.87 ± 1.037
5.418ArgPro: 5.418 ± 0.263
3.87ArgGln: 3.87 ± 2.524
1.548ArgArg: 1.548 ± 0.712
3.87ArgSer: 3.87 ± 1.037
6.966ArgThr: 6.966 ± 1.998
9.288ArgVal: 9.288 ± 1.673
0.774ArgTrp: 0.774 ± 0.387
2.322ArgTyr: 2.322 ± 1.161
0.0ArgXaa: 0.0 ± 0.0
Ser
8.514SerAla: 8.514 ± 3.174
0.0SerCys: 0.0 ± 0.0
2.322SerAsp: 2.322 ± 0.325
3.096SerGlu: 3.096 ± 1.424
0.0SerPhe: 0.0 ± 0.0
4.644SerGly: 4.644 ± 0.65
0.774SerHis: 0.774 ± 1.099
3.096SerIle: 3.096 ± 0.062
2.322SerLys: 2.322 ± 0.325
0.774SerLeu: 0.774 ± 1.099
2.322SerMet: 2.322 ± 1.38
0.774SerAsn: 0.774 ± 1.099
3.096SerPro: 3.096 ± 1.549
2.322SerGln: 2.322 ± 0.325
3.87SerArg: 3.87 ± 0.449
3.096SerSer: 3.096 ± 0.062
6.192SerThr: 6.192 ± 1.611
6.192SerVal: 6.192 ± 1.362
2.322SerTrp: 2.322 ± 0.325
2.322SerTyr: 2.322 ± 0.325
0.0SerXaa: 0.0 ± 0.0
Thr
8.514ThrAla: 8.514 ± 1.286
0.0ThrCys: 0.0 ± 0.0
2.322ThrAsp: 2.322 ± 1.161
0.774ThrGlu: 0.774 ± 0.387
2.322ThrPhe: 2.322 ± 1.812
4.644ThrGly: 4.644 ± 0.836
1.548ThrHis: 1.548 ± 0.774
3.87ThrIle: 3.87 ± 0.449
3.096ThrLys: 3.096 ± 1.549
3.87ThrLeu: 3.87 ± 4.01
2.322ThrMet: 2.322 ± 1.161
2.322ThrAsn: 2.322 ± 1.161
6.192ThrPro: 6.192 ± 0.124
1.548ThrGln: 1.548 ± 0.774
4.644ThrArg: 4.644 ± 0.836
4.644ThrSer: 4.644 ± 0.65
6.192ThrThr: 6.192 ± 1.611
5.418ThrVal: 5.418 ± 1.224
0.0ThrTrp: 0.0 ± 0.0
3.87ThrTyr: 3.87 ± 1.037
0.0ThrXaa: 0.0 ± 0.0
Val
16.254ValAla: 16.254 ± 2.275
0.774ValCys: 0.774 ± 0.387
3.096ValAsp: 3.096 ± 1.549
6.192ValGlu: 6.192 ± 3.097
1.548ValPhe: 1.548 ± 0.774
3.096ValGly: 3.096 ± 1.424
2.322ValHis: 2.322 ± 1.161
3.096ValIle: 3.096 ± 0.062
3.87ValLys: 3.87 ± 0.449
6.966ValLeu: 6.966 ± 0.975
2.322ValMet: 2.322 ± 1.161
3.096ValAsn: 3.096 ± 1.424
7.74ValPro: 7.74 ± 0.899
1.548ValGln: 1.548 ± 0.774
9.288ValArg: 9.288 ± 1.3
8.514ValSer: 8.514 ± 1.687
5.418ValThr: 5.418 ± 1.749
7.74ValVal: 7.74 ± 0.588
2.322ValTrp: 2.322 ± 1.161
1.548ValTyr: 1.548 ± 0.712
0.0ValXaa: 0.0 ± 0.0
Trp
2.322TrpAla: 2.322 ± 0.325
0.0TrpCys: 0.0 ± 0.0
1.548TrpAsp: 1.548 ± 0.774
0.774TrpGlu: 0.774 ± 0.387
1.548TrpPhe: 1.548 ± 0.774
0.774TrpGly: 0.774 ± 0.387
0.774TrpHis: 0.774 ± 1.099
0.774TrpIle: 0.774 ± 1.099
0.774TrpLys: 0.774 ± 0.387
3.096TrpLeu: 3.096 ± 0.062
0.0TrpMet: 0.0 ± 0.0
0.774TrpAsn: 0.774 ± 0.387
1.548TrpPro: 1.548 ± 0.712
0.774TrpGln: 0.774 ± 0.387
1.548TrpArg: 1.548 ± 0.712
0.774TrpSer: 0.774 ± 0.387
2.322TrpThr: 2.322 ± 1.161
2.322TrpVal: 2.322 ± 1.161
3.096TrpTrp: 3.096 ± 1.549
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.322TyrAla: 2.322 ± 1.161
0.0TyrCys: 0.0 ± 0.0
3.096TyrAsp: 3.096 ± 1.549
3.096TyrGlu: 3.096 ± 0.062
0.774TyrPhe: 0.774 ± 0.387
3.87TyrGly: 3.87 ± 1.037
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
3.096TyrLeu: 3.096 ± 1.424
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
3.87TyrPro: 3.87 ± 0.449
0.0TyrGln: 0.0 ± 0.0
2.322TyrArg: 2.322 ± 1.161
0.0TyrSer: 0.0 ± 0.0
4.644TyrThr: 4.644 ± 0.65
1.548TyrVal: 1.548 ± 0.712
0.0TyrTrp: 0.0 ± 0.0
0.774TyrTyr: 0.774 ± 0.387
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1293 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski