Amino acid dipepetide frequency for African elephant polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.146AlaAla: 5.146 ± 2.149
0.572AlaCys: 0.572 ± 0.749
2.859AlaAsp: 2.859 ± 1.428
6.289AlaGlu: 6.289 ± 2.556
1.715AlaPhe: 1.715 ± 0.767
1.144AlaGly: 1.144 ± 0.569
1.144AlaHis: 1.144 ± 0.965
2.287AlaIle: 2.287 ± 0.579
4.002AlaLys: 4.002 ± 1.477
8.576AlaLeu: 8.576 ± 3.863
3.431AlaMet: 3.431 ± 1.428
2.287AlaAsn: 2.287 ± 0.579
5.146AlaPro: 5.146 ± 1.14
4.002AlaGln: 4.002 ± 1.731
2.287AlaArg: 2.287 ± 0.988
4.574AlaSer: 4.574 ± 2.319
5.146AlaThr: 5.146 ± 2.365
3.431AlaVal: 3.431 ± 1.55
1.715AlaTrp: 1.715 ± 0.896
1.144AlaTyr: 1.144 ± 0.832
0.0AlaXaa: 0.0 ± 0.0
Cys
1.144CysAla: 1.144 ± 0.832
1.144CysCys: 1.144 ± 1.498
1.144CysAsp: 1.144 ± 0.832
0.572CysGlu: 0.572 ± 0.534
3.431CysPhe: 3.431 ± 2.01
1.715CysGly: 1.715 ± 0.842
0.0CysHis: 0.0 ± 0.0
1.715CysIle: 1.715 ± 1.403
1.715CysLys: 1.715 ± 0.733
2.287CysLeu: 2.287 ± 1.201
1.144CysMet: 1.144 ± 0.832
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.287CysSer: 2.287 ± 1.427
1.715CysThr: 1.715 ± 1.248
1.715CysVal: 1.715 ± 0.842
0.572CysTrp: 0.572 ± 0.416
1.715CysTyr: 1.715 ± 0.733
0.0CysXaa: 0.0 ± 0.0
Asp
2.287AspAla: 2.287 ± 1.931
0.572AspCys: 0.572 ± 0.749
2.287AspAsp: 2.287 ± 1.2
5.718AspGlu: 5.718 ± 0.952
2.287AspPhe: 2.287 ± 1.663
2.859AspGly: 2.859 ± 0.451
1.715AspHis: 1.715 ± 1.248
2.287AspIle: 2.287 ± 1.138
1.715AspLys: 1.715 ± 0.842
6.289AspLeu: 6.289 ± 1.731
1.715AspMet: 1.715 ± 0.712
4.002AspAsn: 4.002 ± 0.482
3.431AspPro: 3.431 ± 1.241
1.715AspGln: 1.715 ± 1.022
2.287AspArg: 2.287 ± 1.201
4.002AspSer: 4.002 ± 1.804
1.144AspThr: 1.144 ± 0.696
5.146AspVal: 5.146 ± 1.752
1.144AspTrp: 1.144 ± 0.965
4.002AspTyr: 4.002 ± 1.59
0.0AspXaa: 0.0 ± 0.0
Glu
4.574GluAla: 4.574 ± 2.439
1.144GluCys: 1.144 ± 0.569
5.718GluAsp: 5.718 ± 1.508
4.002GluGlu: 4.002 ± 0.741
3.431GluPhe: 3.431 ± 1.105
2.859GluGly: 2.859 ± 1.078
0.0GluHis: 0.0 ± 0.0
0.572GluIle: 0.572 ± 0.575
4.002GluLys: 4.002 ± 1.648
5.146GluLeu: 5.146 ± 1.619
0.572GluMet: 0.572 ± 0.416
0.572GluAsn: 0.572 ± 0.534
2.287GluPro: 2.287 ± 2.135
3.431GluGln: 3.431 ± 1.09
1.715GluArg: 1.715 ± 0.902
2.287GluSer: 2.287 ± 1.2
4.002GluThr: 4.002 ± 0.988
4.002GluVal: 4.002 ± 2.238
0.572GluTrp: 0.572 ± 0.416
1.144GluTyr: 1.144 ± 0.569
0.0GluXaa: 0.0 ± 0.0
Phe
2.287PheAla: 2.287 ± 0.579
2.859PheCys: 2.859 ± 1.559
1.715PheAsp: 1.715 ± 0.767
2.287PheGlu: 2.287 ± 1.086
3.431PhePhe: 3.431 ± 1.241
3.431PheGly: 3.431 ± 1.418
1.715PheHis: 1.715 ± 0.767
1.144PheIle: 1.144 ± 0.517
2.287PheLys: 2.287 ± 1.138
9.72PheLeu: 9.72 ± 1.797
1.715PheMet: 1.715 ± 1.248
2.287PheAsn: 2.287 ± 1.663
4.002PhePro: 4.002 ± 1.602
1.144PheGln: 1.144 ± 0.569
1.715PheArg: 1.715 ± 0.767
6.289PheSer: 6.289 ± 2.027
2.859PheThr: 2.859 ± 1.314
1.715PheVal: 1.715 ± 0.767
0.0PheTrp: 0.0 ± 0.0
0.572PheTyr: 0.572 ± 0.416
0.0PheXaa: 0.0 ± 0.0
Gly
3.431GlyAla: 3.431 ± 1.072
1.144GlyCys: 1.144 ± 0.832
1.144GlyAsp: 1.144 ± 1.067
1.144GlyGlu: 1.144 ± 0.696
2.287GlyPhe: 2.287 ± 0.661
6.861GlyGly: 6.861 ± 2.358
0.0GlyHis: 0.0 ± 0.0
4.002GlyIle: 4.002 ± 1.38
3.431GlyLys: 3.431 ± 1.487
6.289GlyLeu: 6.289 ± 1.829
0.572GlyMet: 0.572 ± 0.416
2.287GlyAsn: 2.287 ± 1.427
5.146GlyPro: 5.146 ± 1.145
4.574GlyGln: 4.574 ± 1.975
4.002GlyArg: 4.002 ± 1.515
2.859GlySer: 2.859 ± 1.586
4.002GlyThr: 4.002 ± 1.949
4.574GlyVal: 4.574 ± 0.7
0.572GlyTrp: 0.572 ± 0.416
1.144GlyTyr: 1.144 ± 1.067
0.0GlyXaa: 0.0 ± 0.0
His
1.144HisAla: 1.144 ± 0.965
0.572HisCys: 0.572 ± 0.416
0.0HisAsp: 0.0 ± 0.0
0.572HisGlu: 0.572 ± 0.416
1.144HisPhe: 1.144 ± 0.569
0.0HisGly: 0.0 ± 0.0
2.859HisHis: 2.859 ± 0.968
0.572HisIle: 0.572 ± 0.416
0.0HisLys: 0.0 ± 0.0
3.431HisLeu: 3.431 ± 1.818
0.572HisMet: 0.572 ± 0.416
0.572HisAsn: 0.572 ± 0.416
2.859HisPro: 2.859 ± 2.081
0.0HisGln: 0.0 ± 0.0
2.287HisArg: 2.287 ± 1.663
4.002HisSer: 4.002 ± 0.823
0.572HisThr: 0.572 ± 0.416
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.146IleAla: 5.146 ± 1.504
0.572IleCys: 0.572 ± 0.534
1.715IleAsp: 1.715 ± 0.767
1.715IleGlu: 1.715 ± 1.022
0.572IlePhe: 0.572 ± 0.534
1.715IleGly: 1.715 ± 1.022
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.144IleLys: 1.144 ± 1.498
2.859IleLeu: 2.859 ± 1.078
1.144IleMet: 1.144 ± 1.294
1.715IleAsn: 1.715 ± 1.16
1.715IlePro: 1.715 ± 1.011
1.144IleGln: 1.144 ± 0.965
2.859IleArg: 2.859 ± 0.775
1.715IleSer: 1.715 ± 1.16
1.144IleThr: 1.144 ± 0.569
1.715IleVal: 1.715 ± 0.536
0.572IleTrp: 0.572 ± 0.749
1.715IleTyr: 1.715 ± 1.248
0.0IleXaa: 0.0 ± 0.0
Lys
3.431LysAla: 3.431 ± 1.939
3.431LysCys: 3.431 ± 2.141
1.715LysAsp: 1.715 ± 0.842
1.715LysGlu: 1.715 ± 0.733
1.144LysPhe: 1.144 ± 0.832
5.146LysGly: 5.146 ± 2.102
4.002LysHis: 4.002 ± 1.16
0.0LysIle: 0.0 ± 0.0
6.289LysLys: 6.289 ± 2.233
2.287LysLeu: 2.287 ± 1.2
1.144LysMet: 1.144 ± 0.569
2.287LysAsn: 2.287 ± 1.138
1.715LysPro: 1.715 ± 0.842
1.715LysGln: 1.715 ± 0.842
8.005LysArg: 8.005 ± 2.887
2.287LysSer: 2.287 ± 0.835
6.861LysThr: 6.861 ± 1.612
5.146LysVal: 5.146 ± 1.145
0.0LysTrp: 0.0 ± 0.0
0.572LysTyr: 0.572 ± 0.416
0.0LysXaa: 0.0 ± 0.0
Leu
4.574LeuAla: 4.574 ± 2.556
3.431LeuCys: 3.431 ± 1.434
5.718LeuAsp: 5.718 ± 1.559
5.718LeuGlu: 5.718 ± 1.428
7.433LeuPhe: 7.433 ± 2.366
6.289LeuGly: 6.289 ± 1.661
2.287LeuHis: 2.287 ± 0.835
2.287LeuIle: 2.287 ± 1.138
3.431LeuLys: 3.431 ± 1.984
12.007LeuLeu: 12.007 ± 1.632
3.431LeuMet: 3.431 ± 1.446
9.148LeuAsn: 9.148 ± 2.212
7.433LeuPro: 7.433 ± 2.389
4.002LeuGln: 4.002 ± 1.098
6.289LeuArg: 6.289 ± 1.033
2.859LeuSer: 2.859 ± 0.584
9.72LeuThr: 9.72 ± 2.469
5.146LeuVal: 5.146 ± 2.657
2.287LeuTrp: 2.287 ± 0.988
1.715LeuTyr: 1.715 ± 0.842
0.0LeuXaa: 0.0 ± 0.0
Met
1.715MetAla: 1.715 ± 0.902
0.572MetCys: 0.572 ± 0.416
2.859MetAsp: 2.859 ± 1.559
2.287MetGlu: 2.287 ± 1.201
0.572MetPhe: 0.572 ± 0.416
2.859MetGly: 2.859 ± 0.584
0.572MetHis: 0.572 ± 0.416
0.0MetIle: 0.0 ± 0.0
2.287MetLys: 2.287 ± 1.427
0.572MetLeu: 0.572 ± 0.416
0.0MetMet: 0.0 ± 0.0
1.144MetAsn: 1.144 ± 0.832
0.572MetPro: 0.572 ± 0.416
2.287MetGln: 2.287 ± 0.768
1.144MetArg: 1.144 ± 0.569
0.0MetSer: 0.0 ± 0.0
1.715MetThr: 1.715 ± 0.842
1.144MetVal: 1.144 ± 0.832
0.572MetTrp: 0.572 ± 0.534
1.144MetTyr: 1.144 ± 0.714
0.0MetXaa: 0.0 ± 0.0
Asn
4.002AsnAla: 4.002 ± 1.391
0.0AsnCys: 0.0 ± 0.0
1.144AsnAsp: 1.144 ± 0.569
0.572AsnGlu: 0.572 ± 0.416
2.859AsnPhe: 2.859 ± 1.586
0.572AsnGly: 0.572 ± 0.416
0.0AsnHis: 0.0 ± 0.0
2.287AsnIle: 2.287 ± 0.988
1.144AsnLys: 1.144 ± 0.832
4.002AsnLeu: 4.002 ± 0.92
1.144AsnMet: 1.144 ± 0.714
1.144AsnAsn: 1.144 ± 0.832
4.574AsnPro: 4.574 ± 1.158
0.572AsnGln: 0.572 ± 0.416
4.002AsnArg: 4.002 ± 2.263
2.859AsnSer: 2.859 ± 0.965
4.574AsnThr: 4.574 ± 1.158
4.574AsnVal: 4.574 ± 1.753
0.0AsnTrp: 0.0 ± 0.0
2.859AsnTyr: 2.859 ± 0.451
0.0AsnXaa: 0.0 ± 0.0
Pro
4.002ProAla: 4.002 ± 1.968
1.144ProCys: 1.144 ± 1.067
6.289ProAsp: 6.289 ± 1.94
5.146ProGlu: 5.146 ± 0.809
2.287ProPhe: 2.287 ± 1.2
3.431ProGly: 3.431 ± 1.533
0.572ProHis: 0.572 ± 0.749
3.431ProIle: 3.431 ± 1.386
4.002ProLys: 4.002 ± 1.16
6.289ProLeu: 6.289 ± 1.528
1.715ProMet: 1.715 ± 0.842
2.859ProAsn: 2.859 ± 1.277
6.861ProPro: 6.861 ± 2.974
2.287ProGln: 2.287 ± 1.138
2.859ProArg: 2.859 ± 1.512
2.859ProSer: 2.859 ± 0.808
4.002ProThr: 4.002 ± 1.634
2.287ProVal: 2.287 ± 1.125
0.0ProTrp: 0.0 ± 0.0
1.715ProTyr: 1.715 ± 0.902
0.0ProXaa: 0.0 ± 0.0
Gln
2.859GlnAla: 2.859 ± 0.808
1.144GlnCys: 1.144 ± 0.832
2.859GlnAsp: 2.859 ± 0.868
1.144GlnGlu: 1.144 ± 0.832
6.289GlnPhe: 6.289 ± 0.576
1.144GlnGly: 1.144 ± 0.569
1.144GlnHis: 1.144 ± 0.517
0.0GlnIle: 0.0 ± 0.0
4.002GlnLys: 4.002 ± 1.477
5.718GlnLeu: 5.718 ± 2.307
0.572GlnMet: 0.572 ± 0.416
0.0GlnAsn: 0.0 ± 0.0
1.715GlnPro: 1.715 ± 1.601
1.715GlnGln: 1.715 ± 0.767
1.144GlnArg: 1.144 ± 0.569
1.715GlnSer: 1.715 ± 0.733
0.572GlnThr: 0.572 ± 0.534
4.574GlnVal: 4.574 ± 2.241
1.144GlnTrp: 1.144 ± 0.965
2.287GlnTyr: 2.287 ± 1.427
0.0GlnXaa: 0.0 ± 0.0
Arg
4.002ArgAla: 4.002 ± 1.59
0.0ArgCys: 0.0 ± 0.0
5.146ArgAsp: 5.146 ± 1.697
1.144ArgGlu: 1.144 ± 0.714
3.431ArgPhe: 3.431 ± 0.493
2.287ArgGly: 2.287 ± 1.065
1.144ArgHis: 1.144 ± 0.832
0.572ArgIle: 0.572 ± 0.534
4.002ArgLys: 4.002 ± 1.999
5.146ArgLeu: 5.146 ± 1.117
1.144ArgMet: 1.144 ± 0.569
2.287ArgAsn: 2.287 ± 0.768
3.431ArgPro: 3.431 ± 0.891
4.002ArgGln: 4.002 ± 1.602
6.289ArgArg: 6.289 ± 3.433
5.718ArgSer: 5.718 ± 1.549
4.002ArgThr: 4.002 ± 3.017
2.859ArgVal: 2.859 ± 1.586
0.0ArgTrp: 0.0 ± 0.0
4.002ArgTyr: 4.002 ± 0.551
0.0ArgXaa: 0.0 ± 0.0
Ser
6.861SerAla: 6.861 ± 1.584
1.144SerCys: 1.144 ± 0.714
4.002SerAsp: 4.002 ± 1.296
1.715SerGlu: 1.715 ± 0.733
2.287SerPhe: 2.287 ± 1.138
5.146SerGly: 5.146 ± 1.213
1.144SerHis: 1.144 ± 0.898
3.431SerIle: 3.431 ± 1.468
5.718SerLys: 5.718 ± 0.85
5.718SerLeu: 5.718 ± 1.167
1.144SerMet: 1.144 ± 0.832
2.287SerAsn: 2.287 ± 1.2
1.144SerPro: 1.144 ± 0.714
1.144SerGln: 1.144 ± 0.696
6.289SerArg: 6.289 ± 2.183
4.002SerSer: 4.002 ± 0.804
4.574SerThr: 4.574 ± 1.569
2.287SerVal: 2.287 ± 1.138
1.144SerTrp: 1.144 ± 0.714
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.146ThrAla: 5.146 ± 2.176
2.859ThrCys: 2.859 ± 1.345
4.574ThrAsp: 4.574 ± 1.372
4.002ThrGlu: 4.002 ± 2.123
4.574ThrPhe: 4.574 ± 1.769
4.002ThrGly: 4.002 ± 1.068
0.0ThrHis: 0.0 ± 0.0
4.002ThrIle: 4.002 ± 0.551
3.431ThrLys: 3.431 ± 0.622
8.576ThrLeu: 8.576 ± 1.62
0.572ThrMet: 0.572 ± 0.416
2.287ThrAsn: 2.287 ± 0.579
6.289ThrPro: 6.289 ± 0.576
5.718ThrGln: 5.718 ± 2.309
2.859ThrArg: 2.859 ± 1.791
1.715ThrSer: 1.715 ± 1.011
5.146ThrThr: 5.146 ± 1.508
4.002ThrVal: 4.002 ± 0.741
1.715ThrTrp: 1.715 ± 1.387
1.715ThrTyr: 1.715 ± 1.022
0.0ThrXaa: 0.0 ± 0.0
Val
1.715ValAla: 1.715 ± 0.741
1.715ValCys: 1.715 ± 1.248
5.146ValAsp: 5.146 ± 0.951
2.859ValGlu: 2.859 ± 1.413
1.144ValPhe: 1.144 ± 0.965
2.287ValGly: 2.287 ± 1.528
0.572ValHis: 0.572 ± 0.534
1.715ValIle: 1.715 ± 0.72
4.002ValLys: 4.002 ± 2.123
5.718ValLeu: 5.718 ± 2.384
0.572ValMet: 0.572 ± 0.448
3.431ValAsn: 3.431 ± 0.646
4.002ValPro: 4.002 ± 1.56
2.287ValGln: 2.287 ± 1.138
2.859ValArg: 2.859 ± 1.532
5.146ValSer: 5.146 ± 0.312
7.433ValThr: 7.433 ± 3.33
2.287ValVal: 2.287 ± 0.661
1.144ValTrp: 1.144 ± 0.85
1.715ValTyr: 1.715 ± 0.767
0.0ValXaa: 0.0 ± 0.0
Trp
1.715TrpAla: 1.715 ± 1.243
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.144TrpGlu: 1.144 ± 0.569
1.715TrpPhe: 1.715 ± 1.243
1.715TrpGly: 1.715 ± 0.902
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.144TrpLys: 1.144 ± 0.832
0.0TrpLeu: 0.0 ± 0.0
0.572TrpMet: 0.572 ± 0.749
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.287TrpSer: 2.287 ± 0.76
1.144TrpThr: 1.144 ± 0.714
1.144TrpVal: 1.144 ± 0.965
0.572TrpTrp: 0.572 ± 0.416
0.572TrpTyr: 0.572 ± 0.416
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.715TyrAla: 1.715 ± 0.842
0.0TyrCys: 0.0 ± 0.0
0.572TyrAsp: 0.572 ± 0.416
2.287TyrGlu: 2.287 ± 1.931
1.144TyrPhe: 1.144 ± 0.569
4.002TyrGly: 4.002 ± 1.5
2.287TyrHis: 2.287 ± 0.835
1.144TyrIle: 1.144 ± 0.965
1.144TyrLys: 1.144 ± 0.714
4.574TyrLeu: 4.574 ± 0.753
0.572TyrMet: 0.572 ± 0.416
2.287TyrAsn: 2.287 ± 1.427
1.715TyrPro: 1.715 ± 1.601
0.0TyrGln: 0.0 ± 0.0
1.715TyrArg: 1.715 ± 0.902
1.715TyrSer: 1.715 ± 1.022
2.859TyrThr: 2.859 ± 0.968
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.859TyrTyr: 2.859 ± 0.451
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1750 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski