Amino acid dipepetide frequency for Hubei sobemo-like virus 40

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.426AlaAla: 7.426 ± 2.702
1.238AlaCys: 1.238 ± 0.942
2.475AlaAsp: 2.475 ± 1.457
2.475AlaGlu: 2.475 ± 0.213
2.475AlaPhe: 2.475 ± 0.213
9.901AlaGly: 9.901 ± 2.489
1.238AlaHis: 1.238 ± 0.729
2.475AlaIle: 2.475 ± 1.457
6.188AlaLys: 6.188 ± 1.973
12.376AlaLeu: 12.376 ± 0.606
0.0AlaMet: 0.0 ± 0.0
2.475AlaAsn: 2.475 ± 1.457
4.95AlaPro: 4.95 ± 0.426
3.713AlaGln: 3.713 ± 2.186
4.95AlaArg: 4.95 ± 2.915
3.713AlaSer: 3.713 ± 1.155
2.475AlaThr: 2.475 ± 0.213
6.188AlaVal: 6.188 ± 3.644
0.0AlaTrp: 0.0 ± 0.0
4.95AlaTyr: 4.95 ± 0.426
0.0AlaXaa: 0.0 ± 0.0
Cys
1.238CysAla: 1.238 ± 0.729
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.238CysGlu: 1.238 ± 0.942
1.238CysPhe: 1.238 ± 0.729
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.238CysLys: 1.238 ± 0.942
3.713CysLeu: 3.713 ± 1.155
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.238CysPro: 1.238 ± 0.729
1.238CysGln: 1.238 ± 0.729
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.238CysThr: 1.238 ± 0.942
2.475CysVal: 2.475 ± 0.213
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.95AspAla: 4.95 ± 0.426
0.0AspCys: 0.0 ± 0.0
3.713AspAsp: 3.713 ± 0.516
2.475AspGlu: 2.475 ± 1.883
0.0AspPhe: 0.0 ± 0.0
2.475AspGly: 2.475 ± 0.213
1.238AspHis: 1.238 ± 0.942
2.475AspIle: 2.475 ± 1.457
1.238AspLys: 1.238 ± 0.942
3.713AspLeu: 3.713 ± 0.516
4.95AspMet: 4.95 ± 2.096
2.475AspAsn: 2.475 ± 1.883
3.713AspPro: 3.713 ± 1.155
2.475AspGln: 2.475 ± 1.457
1.238AspArg: 1.238 ± 0.729
4.95AspSer: 4.95 ± 1.245
1.238AspThr: 1.238 ± 0.942
2.475AspVal: 2.475 ± 0.213
0.0AspTrp: 0.0 ± 0.0
2.475AspTyr: 2.475 ± 1.883
0.0AspXaa: 0.0 ± 0.0
Glu
3.713GluAla: 3.713 ± 0.516
2.475GluCys: 2.475 ± 1.457
4.95GluAsp: 4.95 ± 0.426
3.713GluGlu: 3.713 ± 0.516
0.0GluPhe: 0.0 ± 0.0
7.426GluGly: 7.426 ± 1.032
2.475GluHis: 2.475 ± 0.213
1.238GluIle: 1.238 ± 0.729
1.238GluLys: 1.238 ± 0.729
11.139GluLeu: 11.139 ± 3.464
0.0GluMet: 0.0 ± 0.0
2.475GluAsn: 2.475 ± 0.213
3.713GluPro: 3.713 ± 1.155
3.713GluGln: 3.713 ± 1.155
7.426GluArg: 7.426 ± 1.032
2.475GluSer: 2.475 ± 1.457
6.188GluThr: 6.188 ± 3.644
2.475GluVal: 2.475 ± 0.213
2.475GluTrp: 2.475 ± 0.213
4.95GluTyr: 4.95 ± 2.096
0.0GluXaa: 0.0 ± 0.0
Phe
2.475PheAla: 2.475 ± 1.457
0.0PheCys: 0.0 ± 0.0
1.238PheAsp: 1.238 ± 0.942
1.238PheGlu: 1.238 ± 0.942
1.238PhePhe: 1.238 ± 0.729
4.95PheGly: 4.95 ± 0.426
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.238PheLys: 1.238 ± 0.942
3.713PheLeu: 3.713 ± 1.155
2.475PheMet: 2.475 ± 1.883
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
1.238PheGln: 1.238 ± 0.729
3.713PheArg: 3.713 ± 1.155
4.95PheSer: 4.95 ± 0.426
0.0PheThr: 0.0 ± 0.0
4.95PheVal: 4.95 ± 2.096
1.238PheTrp: 1.238 ± 0.942
1.238PheTyr: 1.238 ± 0.942
0.0PheXaa: 0.0 ± 0.0
Gly
3.713GlyAla: 3.713 ± 0.516
3.713GlyCys: 3.713 ± 0.516
4.95GlyAsp: 4.95 ± 0.426
4.95GlyGlu: 4.95 ± 0.426
3.713GlyPhe: 3.713 ± 2.825
4.95GlyGly: 4.95 ± 1.245
1.238GlyHis: 1.238 ± 0.729
1.238GlyIle: 1.238 ± 0.729
7.426GlyLys: 7.426 ± 2.702
4.95GlyLeu: 4.95 ± 0.426
1.238GlyMet: 1.238 ± 0.661
4.95GlyAsn: 4.95 ± 2.096
1.238GlyPro: 1.238 ± 0.942
3.713GlyGln: 3.713 ± 2.186
4.95GlyArg: 4.95 ± 1.245
4.95GlySer: 4.95 ± 2.915
3.713GlyThr: 3.713 ± 1.155
1.238GlyVal: 1.238 ± 0.729
6.188GlyTrp: 6.188 ± 1.368
3.713GlyTyr: 3.713 ± 1.155
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.238HisAsp: 1.238 ± 0.729
1.238HisGlu: 1.238 ± 0.942
3.713HisPhe: 3.713 ± 0.516
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.475HisLeu: 2.475 ± 1.883
0.0HisMet: 0.0 ± 0.0
1.238HisAsn: 1.238 ± 0.729
2.475HisPro: 2.475 ± 0.213
1.238HisGln: 1.238 ± 0.942
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
2.475HisThr: 2.475 ± 0.213
1.238HisVal: 1.238 ± 0.942
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.713IleAla: 3.713 ± 0.516
0.0IleCys: 0.0 ± 0.0
1.238IleAsp: 1.238 ± 0.942
4.95IleGlu: 4.95 ± 2.096
1.238IlePhe: 1.238 ± 0.942
1.238IleGly: 1.238 ± 0.942
1.238IleHis: 1.238 ± 0.729
3.713IleIle: 3.713 ± 0.516
3.713IleLys: 3.713 ± 2.186
1.238IleLeu: 1.238 ± 0.942
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.475IlePro: 2.475 ± 0.213
1.238IleGln: 1.238 ± 0.942
2.475IleArg: 2.475 ± 1.457
1.238IleSer: 1.238 ± 0.942
1.238IleThr: 1.238 ± 0.729
4.95IleVal: 4.95 ± 1.245
0.0IleTrp: 0.0 ± 0.0
2.475IleTyr: 2.475 ± 0.213
0.0IleXaa: 0.0 ± 0.0
Lys
4.95LysAla: 4.95 ± 1.245
0.0LysCys: 0.0 ± 0.0
3.713LysAsp: 3.713 ± 0.516
6.188LysGlu: 6.188 ± 0.303
0.0LysPhe: 0.0 ± 0.0
2.475LysGly: 2.475 ± 0.213
2.475LysHis: 2.475 ± 1.883
1.238LysIle: 1.238 ± 0.729
1.238LysLys: 1.238 ± 0.729
2.475LysLeu: 2.475 ± 0.213
0.0LysMet: 0.0 ± 0.59
1.238LysAsn: 1.238 ± 0.729
0.0LysPro: 0.0 ± 0.0
3.713LysGln: 3.713 ± 0.516
3.713LysArg: 3.713 ± 2.825
4.95LysSer: 4.95 ± 0.426
3.713LysThr: 3.713 ± 2.186
2.475LysVal: 2.475 ± 1.883
0.0LysTrp: 0.0 ± 0.0
3.713LysTyr: 3.713 ± 2.186
0.0LysXaa: 0.0 ± 0.0
Leu
6.188LeuAla: 6.188 ± 1.368
4.95LeuCys: 4.95 ± 2.096
3.713LeuAsp: 3.713 ± 0.516
8.663LeuGlu: 8.663 ± 4.921
3.713LeuPhe: 3.713 ± 2.825
8.663LeuGly: 8.663 ± 1.581
3.713LeuHis: 3.713 ± 1.155
2.475LeuIle: 2.475 ± 1.883
2.475LeuLys: 2.475 ± 0.213
11.139LeuLeu: 11.139 ± 0.123
3.713LeuMet: 3.713 ± 1.155
1.238LeuAsn: 1.238 ± 0.942
4.95LeuPro: 4.95 ± 0.426
2.475LeuGln: 2.475 ± 0.213
7.426LeuArg: 7.426 ± 2.309
6.188LeuSer: 6.188 ± 1.973
6.188LeuThr: 6.188 ± 1.973
4.95LeuVal: 4.95 ± 0.426
1.238LeuTrp: 1.238 ± 0.942
3.713LeuTyr: 3.713 ± 0.516
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.475MetAsp: 2.475 ± 1.883
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
3.713MetGly: 3.713 ± 0.516
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.238MetLys: 1.238 ± 0.942
2.475MetLeu: 2.475 ± 1.883
0.0MetMet: 0.0 ± 0.0
2.475MetAsn: 2.475 ± 1.883
1.238MetPro: 1.238 ± 0.729
0.0MetGln: 0.0 ± 0.0
2.475MetArg: 2.475 ± 1.457
3.713MetSer: 3.713 ± 2.186
1.238MetThr: 1.238 ± 0.942
2.475MetVal: 2.475 ± 1.883
0.0MetTrp: 0.0 ± 0.0
1.238MetTyr: 1.238 ± 0.729
0.0MetXaa: 0.0 ± 0.0
Asn
2.475AsnAla: 2.475 ± 1.457
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
2.475AsnGlu: 2.475 ± 1.457
0.0AsnPhe: 0.0 ± 0.0
2.475AsnGly: 2.475 ± 0.213
0.0AsnHis: 0.0 ± 0.0
2.475AsnIle: 2.475 ± 0.213
0.0AsnLys: 0.0 ± 0.0
7.426AsnLeu: 7.426 ± 0.639
1.238AsnMet: 1.238 ± 0.729
1.238AsnAsn: 1.238 ± 0.729
2.475AsnPro: 2.475 ± 0.213
0.0AsnGln: 0.0 ± 0.0
1.238AsnArg: 1.238 ± 0.729
2.475AsnSer: 2.475 ± 1.883
0.0AsnThr: 0.0 ± 0.0
1.238AsnVal: 1.238 ± 0.942
1.238AsnTrp: 1.238 ± 0.942
2.475AsnTyr: 2.475 ± 1.883
0.0AsnXaa: 0.0 ± 0.0
Pro
4.95ProAla: 4.95 ± 0.426
0.0ProCys: 0.0 ± 0.0
3.713ProAsp: 3.713 ± 0.516
2.475ProGlu: 2.475 ± 1.457
1.238ProPhe: 1.238 ± 0.729
2.475ProGly: 2.475 ± 1.883
3.713ProHis: 3.713 ± 1.155
1.238ProIle: 1.238 ± 0.942
0.0ProLys: 0.0 ± 0.0
6.188ProLeu: 6.188 ± 0.303
0.0ProMet: 0.0 ± 0.0
1.238ProAsn: 1.238 ± 0.942
1.238ProPro: 1.238 ± 0.942
0.0ProGln: 0.0 ± 0.0
1.238ProArg: 1.238 ± 0.942
3.713ProSer: 3.713 ± 0.516
3.713ProThr: 3.713 ± 1.155
3.713ProVal: 3.713 ± 0.516
1.238ProTrp: 1.238 ± 0.729
2.475ProTyr: 2.475 ± 1.457
0.0ProXaa: 0.0 ± 0.0
Gln
4.95GlnAla: 4.95 ± 1.245
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.713GlnGlu: 3.713 ± 0.516
4.95GlnPhe: 4.95 ± 0.426
1.238GlnGly: 1.238 ± 0.729
0.0GlnHis: 0.0 ± 0.0
3.713GlnIle: 3.713 ± 0.516
0.0GlnLys: 0.0 ± 0.0
2.475GlnLeu: 2.475 ± 1.457
1.238GlnMet: 1.238 ± 0.942
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
3.713GlnGln: 3.713 ± 1.155
2.475GlnArg: 2.475 ± 0.213
6.188GlnSer: 6.188 ± 0.303
3.713GlnThr: 3.713 ± 1.155
1.238GlnVal: 1.238 ± 0.729
1.238GlnTrp: 1.238 ± 0.942
1.238GlnTyr: 1.238 ± 0.942
0.0GlnXaa: 0.0 ± 0.0
Arg
6.188ArgAla: 6.188 ± 1.973
1.238ArgCys: 1.238 ± 0.729
2.475ArgAsp: 2.475 ± 1.883
4.95ArgGlu: 4.95 ± 2.915
2.475ArgPhe: 2.475 ± 1.883
0.0ArgGly: 0.0 ± 0.0
0.0ArgHis: 0.0 ± 0.0
1.238ArgIle: 1.238 ± 0.942
9.901ArgLys: 9.901 ± 0.852
7.426ArgLeu: 7.426 ± 2.309
2.475ArgMet: 2.475 ± 1.457
0.0ArgAsn: 0.0 ± 0.0
2.475ArgPro: 2.475 ± 0.213
3.713ArgGln: 3.713 ± 2.186
7.426ArgArg: 7.426 ± 4.372
4.95ArgSer: 4.95 ± 1.245
2.475ArgThr: 2.475 ± 0.213
6.188ArgVal: 6.188 ± 0.303
2.475ArgTrp: 2.475 ± 0.213
1.238ArgTyr: 1.238 ± 0.729
0.0ArgXaa: 0.0 ± 0.0
Ser
7.426SerAla: 7.426 ± 2.702
0.0SerCys: 0.0 ± 0.0
1.238SerAsp: 1.238 ± 0.942
4.95SerGlu: 4.95 ± 2.915
3.713SerPhe: 3.713 ± 0.516
7.426SerGly: 7.426 ± 0.639
0.0SerHis: 0.0 ± 0.0
3.713SerIle: 3.713 ± 0.516
3.713SerLys: 3.713 ± 1.155
4.95SerLeu: 4.95 ± 0.426
2.475SerMet: 2.475 ± 1.457
1.238SerAsn: 1.238 ± 0.729
3.713SerPro: 3.713 ± 0.516
2.475SerGln: 2.475 ± 0.213
4.95SerArg: 4.95 ± 1.245
4.95SerSer: 4.95 ± 0.426
2.475SerThr: 2.475 ± 1.457
3.713SerVal: 3.713 ± 2.186
0.0SerTrp: 0.0 ± 0.0
4.95SerTyr: 4.95 ± 1.245
0.0SerXaa: 0.0 ± 0.0
Thr
3.713ThrAla: 3.713 ± 2.186
0.0ThrCys: 0.0 ± 0.0
3.713ThrAsp: 3.713 ± 1.155
2.475ThrGlu: 2.475 ± 0.213
1.238ThrPhe: 1.238 ± 0.942
4.95ThrGly: 4.95 ± 0.426
0.0ThrHis: 0.0 ± 0.0
7.426ThrIle: 7.426 ± 3.98
0.0ThrLys: 0.0 ± 0.0
0.0ThrLeu: 0.0 ± 0.0
0.0ThrMet: 0.0 ± 0.0
4.95ThrAsn: 4.95 ± 2.915
4.95ThrPro: 4.95 ± 0.426
1.238ThrGln: 1.238 ± 0.942
4.95ThrArg: 4.95 ± 0.426
1.238ThrSer: 1.238 ± 0.729
2.475ThrThr: 2.475 ± 1.457
8.663ThrVal: 8.663 ± 5.101
1.238ThrTrp: 1.238 ± 0.729
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.713ValAla: 3.713 ± 2.186
0.0ValCys: 0.0 ± 0.0
4.95ValAsp: 4.95 ± 2.096
9.901ValGlu: 9.901 ± 4.16
2.475ValPhe: 2.475 ± 1.883
8.663ValGly: 8.663 ± 5.101
0.0ValHis: 0.0 ± 0.0
2.475ValIle: 2.475 ± 0.213
6.188ValLys: 6.188 ± 0.303
2.475ValLeu: 2.475 ± 0.213
1.238ValMet: 1.238 ± 0.942
2.475ValAsn: 2.475 ± 0.213
1.238ValPro: 1.238 ± 0.729
2.475ValGln: 2.475 ± 1.883
0.0ValArg: 0.0 ± 0.0
3.713ValSer: 3.713 ± 2.186
6.188ValThr: 6.188 ± 0.303
1.238ValVal: 1.238 ± 0.729
2.475ValTrp: 2.475 ± 0.213
3.713ValTyr: 3.713 ± 1.155
0.0ValXaa: 0.0 ± 0.0
Trp
1.238TrpAla: 1.238 ± 0.729
0.0TrpCys: 0.0 ± 0.0
1.238TrpAsp: 1.238 ± 0.942
1.238TrpGlu: 1.238 ± 0.729
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.475TrpLys: 2.475 ± 0.213
2.475TrpLeu: 2.475 ± 1.883
0.0TrpMet: 0.0 ± 0.0
1.238TrpAsn: 1.238 ± 0.942
1.238TrpPro: 1.238 ± 0.729
1.238TrpGln: 1.238 ± 0.942
2.475TrpArg: 2.475 ± 0.213
1.238TrpSer: 1.238 ± 0.729
1.238TrpThr: 1.238 ± 0.942
2.475TrpVal: 2.475 ± 0.213
0.0TrpTrp: 0.0 ± 0.0
1.238TrpTyr: 1.238 ± 0.942
0.0TrpXaa: 0.0 ± 0.0
Tyr
8.663TyrAla: 8.663 ± 0.09
1.238TyrCys: 1.238 ± 0.942
1.238TyrAsp: 1.238 ± 0.729
4.95TyrGlu: 4.95 ± 0.426
2.475TyrPhe: 2.475 ± 0.213
3.713TyrGly: 3.713 ± 2.825
0.0TyrHis: 0.0 ± 0.0
1.238TyrIle: 1.238 ± 0.729
0.0TyrLys: 0.0 ± 0.0
4.95TyrLeu: 4.95 ± 3.767
2.475TyrMet: 2.475 ± 0.213
0.0TyrAsn: 0.0 ± 0.0
1.238TyrPro: 1.238 ± 0.729
2.475TyrGln: 2.475 ± 1.883
6.188TyrArg: 6.188 ± 0.303
2.475TyrSer: 2.475 ± 1.457
1.238TyrThr: 1.238 ± 0.729
1.238TyrVal: 1.238 ± 0.729
0.0TyrTrp: 0.0 ± 0.0
1.238TyrTyr: 1.238 ± 0.729
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (809 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski