Amino acid dipepetide frequency for Mucilaginibacter mali

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.419AlaAla: 7.419 ± 0.091	0.717AlaCys: 0.717 ± 0.02	5.328AlaAsp: 5.328 ± 0.061	4.368AlaGlu: 4.368 ± 0.064	3.511AlaPhe: 3.511 ± 0.047	6.615AlaGly: 6.615 ± 0.08	1.397AlaHis: 1.397 ± 0.029	5.664AlaIle: 5.664 ± 0.061	5.025AlaLys: 5.025 ± 0.064	7.307AlaLeu: 7.307 ± 0.072	2.001AlaMet: 2.001 ± 0.038	4.144AlaAsn: 4.144 ± 0.059	2.815AlaPro: 2.815 ± 0.045	3.387AlaGln: 3.387 ± 0.056	2.898AlaArg: 2.898 ± 0.045	4.583AlaSer: 4.583 ± 0.064	4.74AlaThr: 4.74 ± 0.068	5.142AlaVal: 5.142 ± 0.063	0.906AlaTrp: 0.906 ± 0.025	3.14AlaTyr: 3.14 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.586CysAla: 0.586 ± 0.018	0.139CysCys: 0.139 ± 0.01	0.432CysAsp: 0.432 ± 0.015	0.333CysGlu: 0.333 ± 0.014	0.463CysPhe: 0.463 ± 0.017	0.643CysGly: 0.643 ± 0.023	0.181CysHis: 0.181 ± 0.012	0.623CysIle: 0.623 ± 0.02	0.489CysLys: 0.489 ± 0.016	0.82CysLeu: 0.82 ± 0.02	0.179CysMet: 0.179 ± 0.01	0.369CysAsn: 0.369 ± 0.014	0.312CysPro: 0.312 ± 0.015	0.228CysGln: 0.228 ± 0.011	0.366CysArg: 0.366 ± 0.016	0.495CysSer: 0.495 ± 0.017	0.466CysThr: 0.466 ± 0.017	0.488CysVal: 0.488 ± 0.015	0.096CysTrp: 0.096 ± 0.007	0.337CysTyr: 0.337 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.566AspAla: 4.566 ± 0.056	0.406AspCys: 0.406 ± 0.017	2.85AspAsp: 2.85 ± 0.042	3.424AspGlu: 3.424 ± 0.05	2.803AspPhe: 2.803 ± 0.044	4.247AspGly: 4.247 ± 0.063	1.177AspHis: 1.177 ± 0.028	4.006AspIle: 4.006 ± 0.054	4.132AspLys: 4.132 ± 0.056	4.792AspLeu: 4.792 ± 0.067	1.449AspMet: 1.449 ± 0.031	2.989AspAsn: 2.989 ± 0.042	2.282AspPro: 2.282 ± 0.04	1.858AspGln: 1.858 ± 0.033	2.206AspArg: 2.206 ± 0.038	2.873AspSer: 2.873 ± 0.048	2.98AspThr: 2.98 ± 0.048	3.645AspVal: 3.645 ± 0.048	0.808AspTrp: 0.808 ± 0.024	2.495AspTyr: 2.495 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	4.105GluAla: 4.105 ± 0.061	0.307GluCys: 0.307 ± 0.011	2.422GluAsp: 2.422 ± 0.044	2.875GluGlu: 2.875 ± 0.054	2.067GluPhe: 2.067 ± 0.04	2.985GluGly: 2.985 ± 0.049	1.097GluHis: 1.097 ± 0.026	3.641GluIle: 3.641 ± 0.058	3.901GluLys: 3.901 ± 0.063	5.141GluLeu: 5.141 ± 0.062	1.417GluMet: 1.417 ± 0.031	2.623GluAsn: 2.623 ± 0.043	1.649GluPro: 1.649 ± 0.034	2.358GluGln: 2.358 ± 0.048	2.332GluArg: 2.332 ± 0.041	2.351GluSer: 2.351 ± 0.041	2.646GluThr: 2.646 ± 0.039	3.44GluVal: 3.44 ± 0.048	0.612GluTrp: 0.612 ± 0.02	1.933GluTyr: 1.933 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.504PheAla: 3.504 ± 0.045	0.468PheCys: 0.468 ± 0.016	2.86PheAsp: 2.86 ± 0.039	2.402PheGlu: 2.402 ± 0.037	2.183PhePhe: 2.183 ± 0.043	3.356PheGly: 3.356 ± 0.05	0.783PheHis: 0.783 ± 0.024	3.292PheIle: 3.292 ± 0.044	3.189PheLys: 3.189 ± 0.045	3.816PheLeu: 3.816 ± 0.057	1.12PheMet: 1.12 ± 0.027	2.952PheAsn: 2.952 ± 0.045	1.688PhePro: 1.688 ± 0.034	1.181PheGln: 1.181 ± 0.024	1.73PheArg: 1.73 ± 0.03	3.215PheSer: 3.215 ± 0.05	3.225PheThr: 3.225 ± 0.054	2.697PheVal: 2.697 ± 0.042	0.61PheTrp: 0.61 ± 0.02	2.094PheTyr: 2.094 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	5.038GlyAla: 5.038 ± 0.081	0.631GlyCys: 0.631 ± 0.025	3.775GlyAsp: 3.775 ± 0.052	3.234GlyGlu: 3.234 ± 0.055	3.629GlyPhe: 3.629 ± 0.05	5.349GlyGly: 5.349 ± 0.083	1.38GlyHis: 1.38 ± 0.031	5.401GlyIle: 5.401 ± 0.057	5.341GlyLys: 5.341 ± 0.06	6.389GlyLeu: 6.389 ± 0.078	1.871GlyMet: 1.871 ± 0.036	3.972GlyAsn: 3.972 ± 0.067	1.821GlyPro: 1.821 ± 0.039	2.553GlyGln: 2.553 ± 0.038	2.879GlyArg: 2.879 ± 0.046	4.521GlySer: 4.521 ± 0.067	4.71GlyThr: 4.71 ± 0.084	4.574GlyVal: 4.574 ± 0.054	1.051GlyTrp: 1.051 ± 0.027	3.311GlyTyr: 3.311 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.215HisAla: 1.215 ± 0.028	0.201HisCys: 0.201 ± 0.011	1.042HisAsp: 1.042 ± 0.025	0.944HisGlu: 0.944 ± 0.024	1.115HisPhe: 1.115 ± 0.023	1.256HisGly: 1.256 ± 0.028	0.603HisHis: 0.603 ± 0.019	1.518HisIle: 1.518 ± 0.034	1.067HisLys: 1.067 ± 0.024	1.905HisLeu: 1.905 ± 0.039	0.416HisMet: 0.416 ± 0.014	1.041HisAsn: 1.041 ± 0.025	1.116HisPro: 1.116 ± 0.027	0.849HisGln: 0.849 ± 0.02	0.778HisArg: 0.778 ± 0.022	1.015HisSer: 1.015 ± 0.029	1.129HisThr: 1.129 ± 0.021	1.066HisVal: 1.066 ± 0.029	0.281HisTrp: 0.281 ± 0.013	0.92HisTyr: 0.92 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.083IleAla: 6.083 ± 0.072	0.712IleCys: 0.712 ± 0.023	4.242IleAsp: 4.242 ± 0.053	3.42IleGlu: 3.42 ± 0.054	2.831IlePhe: 2.831 ± 0.045	4.832IleGly: 4.832 ± 0.051	1.241IleHis: 1.241 ± 0.025	4.78IleIle: 4.78 ± 0.059	4.764IleLys: 4.764 ± 0.054	5.597IleLeu: 5.597 ± 0.076	1.358IleMet: 1.358 ± 0.029	4.272IleAsn: 4.272 ± 0.059	3.01IlePro: 3.01 ± 0.047	2.095IleGln: 2.095 ± 0.037	2.912IleArg: 2.912 ± 0.039	4.875IleSer: 4.875 ± 0.054	4.869IleThr: 4.869 ± 0.061	4.064IleVal: 4.064 ± 0.051	0.739IleTrp: 0.739 ± 0.023	2.636IleTyr: 2.636 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	5.566LysAla: 5.566 ± 0.067	0.319LysCys: 0.319 ± 0.013	3.966LysAsp: 3.966 ± 0.05	3.645LysGlu: 3.645 ± 0.053	2.522LysPhe: 2.522 ± 0.039	4.574LysGly: 4.574 ± 0.056	1.272LysHis: 1.272 ± 0.032	4.381LysIle: 4.381 ± 0.064	5.035LysLys: 5.035 ± 0.065	6.189LysLeu: 6.189 ± 0.072	1.905LysMet: 1.905 ± 0.033	3.832LysAsn: 3.832 ± 0.049	3.158LysPro: 3.158 ± 0.047	2.903LysGln: 2.903 ± 0.043	2.661LysArg: 2.661 ± 0.043	3.491LysSer: 3.491 ± 0.046	4.301LysThr: 4.301 ± 0.051	4.318LysVal: 4.318 ± 0.05	0.806LysTrp: 0.806 ± 0.023	2.879LysTyr: 2.879 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	7.251LeuAla: 7.251 ± 0.083	0.833LeuCys: 0.833 ± 0.021	4.612LeuAsp: 4.612 ± 0.06	4.124LeuGlu: 4.124 ± 0.069	4.333LeuPhe: 4.333 ± 0.061	5.634LeuGly: 5.634 ± 0.066	1.782LeuHis: 1.782 ± 0.033	6.101LeuIle: 6.101 ± 0.07	6.82LeuLys: 6.82 ± 0.071	9.168LeuLeu: 9.168 ± 0.1	2.378LeuMet: 2.378 ± 0.045	5.354LeuAsn: 5.354 ± 0.064	4.147LeuPro: 4.147 ± 0.053	3.717LeuGln: 3.717 ± 0.05	3.587LeuArg: 3.587 ± 0.042	6.498LeuSer: 6.498 ± 0.06	5.691LeuThr: 5.691 ± 0.06	5.496LeuVal: 5.496 ± 0.067	0.97LeuTrp: 0.97 ± 0.026	3.369LeuTyr: 3.369 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.136MetAla: 2.136 ± 0.038	0.148MetCys: 0.148 ± 0.008	1.359MetAsp: 1.359 ± 0.029	1.277MetGlu: 1.277 ± 0.029	0.9MetPhe: 0.9 ± 0.026	1.662MetGly: 1.662 ± 0.03	0.488MetHis: 0.488 ± 0.017	1.562MetIle: 1.562 ± 0.038	2.049MetLys: 2.049 ± 0.035	2.291MetLeu: 2.291 ± 0.04	0.701MetMet: 0.701 ± 0.022	1.249MetAsn: 1.249 ± 0.025	1.213MetPro: 1.213 ± 0.029	1.05MetGln: 1.05 ± 0.023	1.138MetArg: 1.138 ± 0.026	1.329MetSer: 1.329 ± 0.028	1.182MetThr: 1.182 ± 0.024	1.637MetVal: 1.637 ± 0.033	0.199MetTrp: 0.199 ± 0.012	0.698MetTyr: 0.698 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	4.215AsnAla: 4.215 ± 0.059	0.44AsnCys: 0.44 ± 0.017	2.881AsnAsp: 2.881 ± 0.044	2.481AsnGlu: 2.481 ± 0.043	2.536AsnPhe: 2.536 ± 0.038	4.381AsnGly: 4.381 ± 0.061	1.068AsnHis: 1.068 ± 0.026	4.136AsnIle: 4.136 ± 0.051	3.545AsnLys: 3.545 ± 0.052	4.88AsnLeu: 4.88 ± 0.056	1.261AsnMet: 1.261 ± 0.025	3.389AsnAsn: 3.389 ± 0.057	2.668AsnPro: 2.668 ± 0.046	1.965AsnGln: 1.965 ± 0.035	2.302AsnArg: 2.302 ± 0.036	3.174AsnSer: 3.174 ± 0.053	3.598AsnThr: 3.598 ± 0.051	3.186AsnVal: 3.186 ± 0.051	0.817AsnTrp: 0.817 ± 0.018	2.765AsnTyr: 2.765 ± 0.052	0.0AsnXaa: 0.0 ± 0.0
Pro	3.982ProAla: 3.982 ± 0.052	0.246ProCys: 0.246 ± 0.012	2.875ProAsp: 2.875 ± 0.044	2.618ProGlu: 2.618 ± 0.038	1.917ProPhe: 1.917 ± 0.03	3.297ProGly: 3.297 ± 0.049	0.769ProHis: 0.769 ± 0.023	2.284ProIle: 2.284 ± 0.038	2.22ProLys: 2.22 ± 0.038	3.371ProLeu: 3.371 ± 0.043	0.859ProMet: 0.859 ± 0.023	2.022ProAsn: 2.022 ± 0.038	1.293ProPro: 1.293 ± 0.04	1.593ProGln: 1.593 ± 0.032	1.196ProArg: 1.196 ± 0.03	2.123ProSer: 2.123 ± 0.036	2.131ProThr: 2.131 ± 0.046	3.551ProVal: 3.551 ± 0.05	0.454ProTrp: 0.454 ± 0.018	1.685ProTyr: 1.685 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.994GlnAla: 2.994 ± 0.043	0.203GlnCys: 0.203 ± 0.011	1.67GlnAsp: 1.67 ± 0.031	1.743GlnGlu: 1.743 ± 0.035	1.672GlnPhe: 1.672 ± 0.031	2.234GlnGly: 2.234 ± 0.043	0.884GlnHis: 0.884 ± 0.024	2.373GlnIle: 2.373 ± 0.038	2.616GlnLys: 2.616 ± 0.043	4.028GlnLeu: 4.028 ± 0.052	0.962GlnMet: 0.962 ± 0.027	2.038GlnAsn: 2.038 ± 0.039	1.686GlnPro: 1.686 ± 0.035	2.395GlnGln: 2.395 ± 0.086	1.588GlnArg: 1.588 ± 0.036	2.151GlnSer: 2.151 ± 0.041	2.371GlnThr: 2.371 ± 0.044	2.53GlnVal: 2.53 ± 0.04	0.454GlnTrp: 0.454 ± 0.016	1.666GlnTyr: 1.666 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.737ArgAla: 2.737 ± 0.041	0.254ArgCys: 0.254 ± 0.011	2.242ArgAsp: 2.242 ± 0.034	2.159ArgGlu: 2.159 ± 0.041	2.111ArgPhe: 2.111 ± 0.039	2.382ArgGly: 2.382 ± 0.043	0.787ArgHis: 0.787 ± 0.023	2.944ArgIle: 2.944 ± 0.042	2.703ArgLys: 2.703 ± 0.042	3.802ArgLeu: 3.802 ± 0.051	1.123ArgMet: 1.123 ± 0.026	2.112ArgAsn: 2.112 ± 0.034	1.461ArgPro: 1.461 ± 0.036	1.653ArgGln: 1.653 ± 0.041	1.727ArgArg: 1.727 ± 0.035	2.285ArgSer: 2.285 ± 0.037	2.118ArgThr: 2.118 ± 0.038	2.581ArgVal: 2.581 ± 0.038	0.546ArgTrp: 0.546 ± 0.018	1.961ArgTyr: 1.961 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	5.153SerAla: 5.153 ± 0.06	0.501SerCys: 0.501 ± 0.018	2.98SerAsp: 2.98 ± 0.044	2.478SerGlu: 2.478 ± 0.048	3.198SerPhe: 3.198 ± 0.045	5.093SerGly: 5.093 ± 0.078	1.109SerHis: 1.109 ± 0.029	4.224SerIle: 4.224 ± 0.052	3.458SerLys: 3.458 ± 0.053	5.571SerLeu: 5.571 ± 0.063	1.27SerMet: 1.27 ± 0.025	3.09SerAsn: 3.09 ± 0.045	2.497SerPro: 2.497 ± 0.04	1.865SerGln: 1.865 ± 0.036	2.382SerArg: 2.382 ± 0.033	3.551SerSer: 3.551 ± 0.061	3.65SerThr: 3.65 ± 0.056	4.202SerVal: 4.202 ± 0.053	0.734SerTrp: 0.734 ± 0.022	2.664SerTyr: 2.664 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	5.365ThrAla: 5.365 ± 0.084	0.403ThrCys: 0.403 ± 0.016	3.846ThrAsp: 3.846 ± 0.056	2.95ThrGlu: 2.95 ± 0.041	2.733ThrPhe: 2.733 ± 0.044	5.385ThrGly: 5.385 ± 0.076	1.073ThrHis: 1.073 ± 0.024	4.401ThrIle: 4.401 ± 0.057	3.171ThrLys: 3.171 ± 0.042	5.588ThrLeu: 5.588 ± 0.065	1.142ThrMet: 1.142 ± 0.029	3.075ThrAsn: 3.075 ± 0.052	2.912ThrPro: 2.912 ± 0.049	2.022ThrGln: 2.022 ± 0.033	2.177ThrArg: 2.177 ± 0.036	3.499ThrSer: 3.499 ± 0.062	3.862ThrThr: 3.862 ± 0.071	4.317ThrVal: 4.317 ± 0.066	0.751ThrTrp: 0.751 ± 0.024	2.711ThrTyr: 2.711 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	5.18ValAla: 5.18 ± 0.064	0.607ValCys: 0.607 ± 0.018	3.47ValAsp: 3.47 ± 0.048	3.034ValGlu: 3.034 ± 0.047	3.091ValPhe: 3.091 ± 0.047	3.732ValGly: 3.732 ± 0.059	1.056ValHis: 1.056 ± 0.025	4.677ValIle: 4.677 ± 0.06	4.746ValLys: 4.746 ± 0.057	5.96ValLeu: 5.96 ± 0.065	1.623ValMet: 1.623 ± 0.035	3.814ValAsn: 3.814 ± 0.053	2.564ValPro: 2.564 ± 0.042	2.101ValGln: 2.101 ± 0.03	2.38ValArg: 2.38 ± 0.037	4.356ValSer: 4.356 ± 0.052	4.124ValThr: 4.124 ± 0.052	4.344ValVal: 4.344 ± 0.052	0.768ValTrp: 0.768 ± 0.022	2.741ValTyr: 2.741 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.904TrpAla: 0.904 ± 0.024	0.153TrpCys: 0.153 ± 0.009	0.701TrpAsp: 0.701 ± 0.02	0.622TrpGlu: 0.622 ± 0.019	0.598TrpPhe: 0.598 ± 0.021	0.864TrpGly: 0.864 ± 0.024	0.312TrpHis: 0.312 ± 0.013	0.726TrpIle: 0.726 ± 0.025	0.781TrpLys: 0.781 ± 0.023	1.277TrpLeu: 1.277 ± 0.031	0.382TrpMet: 0.382 ± 0.015	0.671TrpAsn: 0.671 ± 0.023	0.416TrpPro: 0.416 ± 0.018	0.637TrpGln: 0.637 ± 0.019	0.528TrpArg: 0.528 ± 0.018	0.677TrpSer: 0.677 ± 0.02	0.664TrpThr: 0.664 ± 0.022	0.761TrpVal: 0.761 ± 0.022	0.227TrpTrp: 0.227 ± 0.013	0.5TrpTyr: 0.5 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.108TyrAla: 3.108 ± 0.041	0.357TyrCys: 0.357 ± 0.015	2.436TyrAsp: 2.436 ± 0.046	1.772TyrGlu: 1.772 ± 0.035	2.153TyrPhe: 2.153 ± 0.036	2.911TyrGly: 2.911 ± 0.044	1.019TyrHis: 1.019 ± 0.028	2.597TyrIle: 2.597 ± 0.042	2.672TyrLys: 2.672 ± 0.038	3.973TyrLeu: 3.973 ± 0.046	0.852TyrMet: 0.852 ± 0.023	2.68TyrAsn: 2.68 ± 0.056	1.778TyrPro: 1.778 ± 0.033	1.842TyrGln: 1.842 ± 0.037	1.922TyrArg: 1.922 ± 0.034	2.608TyrSer: 2.608 ± 0.042	2.925TyrThr: 2.925 ± 0.051	2.327TyrVal: 2.327 ± 0.04	0.572TyrTrp: 0.572 ± 0.018	2.062TyrTyr: 2.062 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5033 proteins (1747214 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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