Amino acid dipepetide frequency for Bivalve hepelivirus G

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.132AlaAla: 3.132 ± 2.331
0.0AlaCys: 0.0 ± 0.0
3.579AlaAsp: 3.579 ± 2.427
2.685AlaGlu: 2.685 ± 1.03
4.922AlaPhe: 4.922 ± 0.946
1.79AlaGly: 1.79 ± 1.433
0.895AlaHis: 0.895 ± 0.496
4.027AlaIle: 4.027 ± 0.873
3.579AlaLys: 3.579 ± 0.179
4.922AlaLeu: 4.922 ± 1.815
2.685AlaMet: 2.685 ± 0.656
4.027AlaAsn: 4.027 ± 0.131
2.237AlaPro: 2.237 ± 0.692
1.79AlaGln: 1.79 ± 1.433
2.237AlaArg: 2.237 ± 0.692
5.369AlaSer: 5.369 ± 1.413
2.237AlaThr: 2.237 ± 0.494
4.474AlaVal: 4.474 ± 1.228
0.447AlaTrp: 0.447 ± 0.962
4.027AlaTyr: 4.027 ± 2.173
0.0AlaXaa: 0.0 ± 0.0
Cys
1.342CysAla: 1.342 ± 0.781
0.447CysCys: 0.447 ± 0.538
0.895CysAsp: 0.895 ± 0.496
0.895CysGlu: 0.895 ± 0.496
0.447CysPhe: 0.447 ± 0.248
0.447CysGly: 0.447 ± 0.248
0.895CysHis: 0.895 ± 0.496
0.447CysIle: 0.447 ± 0.248
3.132CysLys: 3.132 ± 1.128
1.342CysLeu: 1.342 ± 0.744
0.447CysMet: 0.447 ± 0.248
1.79CysAsn: 1.79 ± 0.65
0.447CysPro: 0.447 ± 0.248
0.0CysGln: 0.0 ± 0.0
0.447CysArg: 0.447 ± 0.962
0.447CysSer: 0.447 ± 0.248
0.447CysThr: 0.447 ± 0.248
0.447CysVal: 0.447 ± 0.248
0.895CysTrp: 0.895 ± 0.382
1.342CysTyr: 1.342 ± 0.9
0.0CysXaa: 0.0 ± 0.0
Asp
4.027AspAla: 4.027 ± 0.622
0.447AspCys: 0.447 ± 0.962
2.685AspAsp: 2.685 ± 1.03
4.027AspGlu: 4.027 ± 1.619
4.027AspPhe: 4.027 ± 0.131
2.685AspGly: 2.685 ± 0.707
1.342AspHis: 1.342 ± 0.9
5.817AspIle: 5.817 ± 3.226
5.369AspLys: 5.369 ± 1.969
4.474AspLeu: 4.474 ± 1.345
1.342AspMet: 1.342 ± 0.353
4.474AspAsn: 4.474 ± 0.354
1.79AspPro: 1.79 ± 1.433
1.79AspGln: 1.79 ± 0.477
0.447AspArg: 0.447 ± 0.962
3.579AspSer: 3.579 ± 0.179
3.579AspThr: 3.579 ± 1.527
5.369AspVal: 5.369 ± 1.394
0.0AspTrp: 0.0 ± 0.0
4.027AspTyr: 4.027 ± 0.873
0.0AspXaa: 0.0 ± 0.0
Glu
1.79GluAla: 1.79 ± 0.477
1.79GluCys: 1.79 ± 0.477
1.79GluAsp: 1.79 ± 1.776
2.685GluGlu: 2.685 ± 1.454
2.685GluPhe: 2.685 ± 1.454
0.895GluGly: 0.895 ± 0.841
1.342GluHis: 1.342 ± 0.744
2.685GluIle: 2.685 ± 1.489
2.685GluLys: 2.685 ± 1.03
6.264GluLeu: 6.264 ± 2.552
1.79GluMet: 1.79 ± 0.821
1.79GluAsn: 1.79 ± 0.993
0.895GluPro: 0.895 ± 0.496
1.342GluGln: 1.342 ± 1.398
1.79GluArg: 1.79 ± 0.477
4.474GluSer: 4.474 ± 1.228
2.685GluThr: 2.685 ± 0.895
1.79GluVal: 1.79 ± 0.798
1.342GluTrp: 1.342 ± 0.744
0.895GluTyr: 0.895 ± 0.496
0.0GluXaa: 0.0 ± 0.0
Phe
2.685PheAla: 2.685 ± 0.435
1.342PheCys: 1.342 ± 0.353
4.922PheAsp: 4.922 ± 1.27
0.895PheGlu: 0.895 ± 0.841
0.895PhePhe: 0.895 ± 0.841
1.342PheGly: 1.342 ± 0.851
0.447PheHis: 0.447 ± 0.538
4.922PheIle: 4.922 ± 1.03
3.132PheLys: 3.132 ± 0.412
3.579PheLeu: 3.579 ± 1.031
0.895PheMet: 0.895 ± 0.382
4.474PheAsn: 4.474 ± 1.345
0.895PhePro: 0.895 ± 0.841
1.342PheGln: 1.342 ± 0.744
0.447PheArg: 0.447 ± 0.248
2.237PheSer: 2.237 ± 0.673
2.237PheThr: 2.237 ± 1.241
4.027PheVal: 4.027 ± 0.622
0.0PheTrp: 0.0 ± 0.0
1.79PheTyr: 1.79 ± 0.65
0.0PheXaa: 0.0 ± 0.0
Gly
3.132GlyAla: 3.132 ± 1.094
0.447GlyCys: 0.447 ± 0.538
1.342GlyAsp: 1.342 ± 0.781
1.342GlyGlu: 1.342 ± 0.744
1.342GlyPhe: 1.342 ± 1.79
3.132GlyGly: 3.132 ± 1.737
0.447GlyHis: 0.447 ± 0.248
4.027GlyIle: 4.027 ± 2.053
2.685GlyLys: 2.685 ± 0.707
2.685GlyLeu: 2.685 ± 1.145
2.237GlyMet: 2.237 ± 1.604
2.685GlyAsn: 2.685 ± 0.435
1.79GlyPro: 1.79 ± 0.764
0.895GlyGln: 0.895 ± 0.841
2.237GlyArg: 2.237 ± 0.494
2.237GlySer: 2.237 ± 1.273
3.132GlyThr: 3.132 ± 0.801
4.474GlyVal: 4.474 ± 0.989
0.0GlyTrp: 0.0 ± 0.0
3.579GlyTyr: 3.579 ± 0.669
0.0GlyXaa: 0.0 ± 0.0
His
1.342HisAla: 1.342 ± 0.851
0.895HisCys: 0.895 ± 0.496
1.342HisAsp: 1.342 ± 0.744
1.342HisGlu: 1.342 ± 0.353
0.447HisPhe: 0.447 ± 0.248
0.447HisGly: 0.447 ± 0.538
0.447HisHis: 0.447 ± 0.248
0.895HisIle: 0.895 ± 0.496
2.237HisLys: 2.237 ± 1.241
3.579HisLeu: 3.579 ± 0.953
1.342HisMet: 1.342 ± 0.781
0.447HisAsn: 0.447 ± 0.248
1.342HisPro: 1.342 ± 0.353
0.895HisGln: 0.895 ± 0.382
0.895HisArg: 0.895 ± 0.496
1.342HisSer: 1.342 ± 0.781
1.342HisThr: 1.342 ± 0.781
0.895HisVal: 0.895 ± 0.382
0.447HisTrp: 0.447 ± 0.248
1.342HisTyr: 1.342 ± 0.851
0.0HisXaa: 0.0 ± 0.0
Ile
7.606IleAla: 7.606 ± 0.74
1.342IleCys: 1.342 ± 0.744
5.817IleAsp: 5.817 ± 1.532
2.685IleGlu: 2.685 ± 0.895
1.342IlePhe: 1.342 ± 0.744
3.132IleGly: 3.132 ± 1.495
1.342IleHis: 1.342 ± 0.744
7.606IleIle: 7.606 ± 0.962
6.264IleLys: 6.264 ± 1.809
2.685IleLeu: 2.685 ± 0.707
0.447IleMet: 0.447 ± 0.248
8.501IleAsn: 8.501 ± 2.481
2.237IlePro: 2.237 ± 0.673
2.237IleGln: 2.237 ± 1.604
4.027IleArg: 4.027 ± 1.608
5.369IleSer: 5.369 ± 0.826
3.579IleThr: 3.579 ± 0.855
5.369IleVal: 5.369 ± 1.563
0.0IleTrp: 0.0 ± 0.0
3.132IleTyr: 3.132 ± 1.207
0.0IleXaa: 0.0 ± 0.0
Lys
1.79LysAla: 1.79 ± 0.65
1.342LysCys: 1.342 ± 0.744
5.369LysAsp: 5.369 ± 1.79
2.685LysGlu: 2.685 ± 1.03
4.474LysPhe: 4.474 ± 1.851
1.79LysGly: 1.79 ± 1.681
1.342LysHis: 1.342 ± 0.353
7.606LysIle: 7.606 ± 3.894
6.711LysLys: 6.711 ± 2.287
5.817LysLeu: 5.817 ± 0.494
1.342LysMet: 1.342 ± 0.516
3.132LysAsn: 3.132 ± 1.128
4.027LysPro: 4.027 ± 2.029
4.027LysGln: 4.027 ± 1.139
2.237LysArg: 2.237 ± 0.692
5.817LysSer: 5.817 ± 0.642
7.606LysThr: 7.606 ± 1.943
4.474LysVal: 4.474 ± 1.095
1.342LysTrp: 1.342 ± 1.398
4.027LysTyr: 4.027 ± 1.128
0.0LysXaa: 0.0 ± 0.0
Leu
4.474LeuAla: 4.474 ± 1.345
0.895LeuCys: 0.895 ± 0.496
3.579LeuAsp: 3.579 ± 1.031
2.685LeuGlu: 2.685 ± 2.522
4.474LeuPhe: 4.474 ± 0.408
1.79LeuGly: 1.79 ± 0.798
2.237LeuHis: 2.237 ± 1.604
4.474LeuIle: 4.474 ± 1.095
5.369LeuLys: 5.369 ± 1.394
3.579LeuLeu: 3.579 ± 1.406
1.342LeuMet: 1.342 ± 0.353
5.817LeuAsn: 5.817 ± 0.494
4.027LeuPro: 4.027 ± 1.06
3.132LeuGln: 3.132 ± 1.128
3.579LeuArg: 3.579 ± 1.031
6.264LeuSer: 6.264 ± 0.544
4.027LeuThr: 4.027 ± 2.173
5.369LeuVal: 5.369 ± 1.43
0.447LeuTrp: 0.447 ± 0.538
4.474LeuTyr: 4.474 ± 3.331
0.0LeuXaa: 0.0 ± 0.0
Met
0.895MetAla: 0.895 ± 1.072
0.0MetCys: 0.0 ± 0.0
2.685MetAsp: 2.685 ± 0.435
0.447MetGlu: 0.447 ± 0.248
0.895MetPhe: 0.895 ± 0.496
0.895MetGly: 0.895 ± 0.382
1.342MetHis: 1.342 ± 0.744
1.79MetIle: 1.79 ± 0.993
2.685MetLys: 2.685 ± 1.489
3.132MetLeu: 3.132 ± 3.525
0.447MetMet: 0.447 ± 0.248
1.79MetAsn: 1.79 ± 0.764
1.79MetPro: 1.79 ± 1.433
2.237MetGln: 2.237 ± 1.581
2.237MetArg: 2.237 ± 1.92
1.79MetSer: 1.79 ± 0.764
1.79MetThr: 1.79 ± 0.477
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.447MetTyr: 0.447 ± 0.248
0.0MetXaa: 0.0 ± 0.0
Asn
3.579AsnAla: 3.579 ± 0.953
0.895AsnCys: 0.895 ± 0.496
4.027AsnAsp: 4.027 ± 1.436
5.817AsnGlu: 5.817 ± 2.021
3.132AsnPhe: 3.132 ± 1.094
3.132AsnGly: 3.132 ± 1.65
1.79AsnHis: 1.79 ± 0.993
4.922AsnIle: 4.922 ± 1.377
6.264AsnLys: 6.264 ± 3.474
5.369AsnLeu: 5.369 ± 0.826
1.79AsnMet: 1.79 ± 0.65
5.817AsnAsn: 5.817 ± 1.49
1.79AsnPro: 1.79 ± 0.477
1.342AsnGln: 1.342 ± 0.851
4.027AsnArg: 4.027 ± 1.608
3.579AsnSer: 3.579 ± 0.855
5.817AsnThr: 5.817 ± 0.911
4.922AsnVal: 4.922 ± 1.377
0.447AsnTrp: 0.447 ± 0.248
2.685AsnTyr: 2.685 ± 1.03
0.0AsnXaa: 0.0 ± 0.0
Pro
2.685ProAla: 2.685 ± 0.707
0.895ProCys: 0.895 ± 0.382
2.237ProAsp: 2.237 ± 0.903
1.342ProGlu: 1.342 ± 0.9
1.79ProPhe: 1.79 ± 0.477
2.237ProGly: 2.237 ± 0.887
0.895ProHis: 0.895 ± 1.077
3.132ProIle: 3.132 ± 1.65
2.237ProLys: 2.237 ± 1.273
2.237ProLeu: 2.237 ± 0.494
0.895ProMet: 0.895 ± 1.077
3.132ProAsn: 3.132 ± 1.65
0.895ProPro: 0.895 ± 1.077
0.895ProGln: 0.895 ± 0.496
0.895ProArg: 0.895 ± 0.382
4.027ProSer: 4.027 ± 1.436
3.132ProThr: 3.132 ± 2.331
2.237ProVal: 2.237 ± 1.273
0.447ProTrp: 0.447 ± 0.538
3.579ProTyr: 3.579 ± 1.406
0.0ProXaa: 0.0 ± 0.0
Gln
2.685GlnAla: 2.685 ± 1.337
1.79GlnCys: 1.79 ± 0.798
3.132GlnAsp: 3.132 ± 1.65
0.447GlnGlu: 0.447 ± 0.248
0.895GlnPhe: 0.895 ± 1.077
3.132GlnGly: 3.132 ± 0.801
1.342GlnHis: 1.342 ± 0.781
4.027GlnIle: 4.027 ± 2.029
1.79GlnLys: 1.79 ± 0.798
2.685GlnLeu: 2.685 ± 0.435
0.447GlnMet: 0.447 ± 0.248
1.79GlnAsn: 1.79 ± 0.764
0.895GlnPro: 0.895 ± 1.072
0.895GlnGln: 0.895 ± 0.382
0.895GlnArg: 0.895 ± 0.496
1.79GlnSer: 1.79 ± 1.681
2.685GlnThr: 2.685 ± 1.145
2.237GlnVal: 2.237 ± 0.903
0.0GlnTrp: 0.0 ± 0.0
1.342GlnTyr: 1.342 ± 0.781
0.0GlnXaa: 0.0 ± 0.0
Arg
1.79ArgAla: 1.79 ± 0.798
1.342ArgCys: 1.342 ± 0.744
0.447ArgAsp: 0.447 ± 0.962
3.579ArgGlu: 3.579 ± 1.597
1.79ArgPhe: 1.79 ± 0.477
2.237ArgGly: 2.237 ± 0.673
1.342ArgHis: 1.342 ± 0.744
4.922ArgIle: 4.922 ± 0.598
1.79ArgLys: 1.79 ± 2.153
1.342ArgLeu: 1.342 ± 0.781
2.237ArgMet: 2.237 ± 0.294
0.895ArgAsn: 0.895 ± 0.382
1.79ArgPro: 1.79 ± 1.433
1.342ArgGln: 1.342 ± 0.744
1.79ArgArg: 1.79 ± 0.65
4.922ArgSer: 4.922 ± 0.263
2.237ArgThr: 2.237 ± 1.92
3.579ArgVal: 3.579 ± 0.179
0.0ArgTrp: 0.0 ± 0.0
1.342ArgTyr: 1.342 ± 0.744
0.0ArgXaa: 0.0 ± 0.0
Ser
4.027SerAla: 4.027 ± 0.622
0.447SerCys: 0.447 ± 0.248
4.474SerAsp: 4.474 ± 0.408
3.132SerGlu: 3.132 ± 1.333
2.685SerPhe: 2.685 ± 0.435
3.132SerGly: 3.132 ± 0.412
2.237SerHis: 2.237 ± 1.604
3.579SerIle: 3.579 ± 0.953
7.606SerLys: 7.606 ± 0.945
3.579SerLeu: 3.579 ± 1.031
4.027SerMet: 4.027 ± 1.368
5.817SerAsn: 5.817 ± 1.091
4.474SerPro: 4.474 ± 1.909
3.132SerGln: 3.132 ± 1.65
3.132SerArg: 3.132 ± 1.333
3.579SerSer: 3.579 ± 2.171
5.817SerThr: 5.817 ± 1.302
3.132SerVal: 3.132 ± 2.439
2.237SerTrp: 2.237 ± 1.581
3.132SerTyr: 3.132 ± 0.801
0.0SerXaa: 0.0 ± 0.0
Thr
4.474ThrAla: 4.474 ± 1.909
0.0ThrCys: 0.0 ± 0.0
4.027ThrAsp: 4.027 ± 1.608
1.342ThrGlu: 1.342 ± 0.744
2.685ThrPhe: 2.685 ± 0.707
2.685ThrGly: 2.685 ± 0.435
2.685ThrHis: 2.685 ± 1.145
4.027ThrIle: 4.027 ± 2.233
4.922ThrLys: 4.922 ± 2.142
4.474ThrLeu: 4.474 ± 1.806
1.79ThrMet: 1.79 ± 0.798
3.132ThrAsn: 3.132 ± 1.128
3.132ThrPro: 3.132 ± 1.827
3.132ThrGln: 3.132 ± 0.412
4.474ThrArg: 4.474 ± 0.408
3.579ThrSer: 3.579 ± 2.171
6.264ThrThr: 6.264 ± 1.144
5.817ThrVal: 5.817 ± 0.642
1.342ThrTrp: 1.342 ± 0.353
2.685ThrTyr: 2.685 ± 1.03
0.0ThrXaa: 0.0 ± 0.0
Val
4.474ValAla: 4.474 ± 0.354
0.895ValCys: 0.895 ± 0.382
5.817ValAsp: 5.817 ± 2.021
1.79ValGlu: 1.79 ± 0.477
1.79ValPhe: 1.79 ± 0.993
4.922ValGly: 4.922 ± 0.263
0.447ValHis: 0.447 ± 0.248
3.579ValIle: 3.579 ± 0.669
3.579ValLys: 3.579 ± 0.669
5.369ValLeu: 5.369 ± 2.06
0.447ValMet: 0.447 ± 0.248
6.711ValAsn: 6.711 ± 1.483
3.132ValPro: 3.132 ± 1.094
1.342ValGln: 1.342 ± 0.9
1.342ValArg: 1.342 ± 0.851
7.606ValSer: 7.606 ± 2.32
4.922ValThr: 4.922 ± 0.263
5.817ValVal: 5.817 ± 1.068
0.447ValTrp: 0.447 ± 0.538
3.579ValTyr: 3.579 ± 1.367
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.447TrpCys: 0.447 ± 0.962
0.0TrpAsp: 0.0 ± 0.0
0.895TrpGlu: 0.895 ± 0.841
1.342TrpPhe: 1.342 ± 0.9
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.447TrpLys: 0.447 ± 0.248
1.342TrpLeu: 1.342 ± 0.353
0.447TrpMet: 0.447 ± 0.538
0.895TrpAsn: 0.895 ± 1.077
0.0TrpPro: 0.0 ± 0.0
0.447TrpGln: 0.447 ± 0.538
0.895TrpArg: 0.895 ± 0.496
0.895TrpSer: 0.895 ± 1.077
0.447TrpThr: 0.447 ± 0.538
0.447TrpVal: 0.447 ± 0.248
0.0TrpTrp: 0.0 ± 0.0
0.895TrpTyr: 0.895 ± 0.841
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.132TyrAla: 3.132 ± 2.439
1.342TyrCys: 1.342 ± 0.744
3.132TyrAsp: 3.132 ± 0.801
2.685TyrGlu: 2.685 ± 1.337
0.447TyrPhe: 0.447 ± 0.248
4.027TyrGly: 4.027 ± 2.251
0.447TyrHis: 0.447 ± 0.248
2.237TyrIle: 2.237 ± 1.241
4.922TyrLys: 4.922 ± 1.29
3.579TyrLeu: 3.579 ± 1.597
0.447TyrMet: 0.447 ± 0.962
4.027TyrAsn: 4.027 ± 1.139
2.237TyrPro: 2.237 ± 0.673
2.685TyrGln: 2.685 ± 2.811
2.685TyrArg: 2.685 ± 1.454
4.474TyrSer: 4.474 ± 0.408
2.685TyrThr: 2.685 ± 1.489
3.132TyrVal: 3.132 ± 1.737
0.0TyrTrp: 0.0 ± 0.0
5.817TyrTyr: 5.817 ± 2.586
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski