Amino acid dipepetide frequency for Salibacter halophilus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.831AlaAla: 3.831 ± 0.086	0.525AlaCys: 0.525 ± 0.026	3.689AlaAsp: 3.689 ± 0.065	4.032AlaGlu: 4.032 ± 0.092	3.077AlaPhe: 3.077 ± 0.065	4.534AlaGly: 4.534 ± 0.078	1.099AlaHis: 1.099 ± 0.041	4.636AlaIle: 4.636 ± 0.078	4.062AlaLys: 4.062 ± 0.087	5.599AlaLeu: 5.599 ± 0.104	1.462AlaMet: 1.462 ± 0.044	3.044AlaAsn: 3.044 ± 0.061	1.857AlaPro: 1.857 ± 0.049	2.51AlaGln: 2.51 ± 0.055	2.244AlaArg: 2.244 ± 0.059	4.123AlaSer: 4.123 ± 0.096	3.274AlaThr: 3.274 ± 0.109	4.095AlaVal: 4.095 ± 0.072	0.577AlaTrp: 0.577 ± 0.025	2.327AlaTyr: 2.327 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.493CysAla: 0.493 ± 0.032	0.094CysCys: 0.094 ± 0.012	0.573CysAsp: 0.573 ± 0.046	0.571CysGlu: 0.571 ± 0.029	0.354CysPhe: 0.354 ± 0.026	0.717CysGly: 0.717 ± 0.035	0.171CysHis: 0.171 ± 0.015	0.486CysIle: 0.486 ± 0.028	0.367CysLys: 0.367 ± 0.02	0.511CysLeu: 0.511 ± 0.027	0.133CysMet: 0.133 ± 0.012	0.488CysAsn: 0.488 ± 0.04	0.343CysPro: 0.343 ± 0.024	0.266CysGln: 0.266 ± 0.018	0.242CysArg: 0.242 ± 0.014	0.649CysSer: 0.649 ± 0.036	0.473CysThr: 0.473 ± 0.026	0.483CysVal: 0.483 ± 0.028	0.069CysTrp: 0.069 ± 0.008	0.302CysTyr: 0.302 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.256AspAla: 3.256 ± 0.067	0.46AspCys: 0.46 ± 0.022	3.445AspAsp: 3.445 ± 0.071	4.675AspGlu: 4.675 ± 0.093	3.455AspPhe: 3.455 ± 0.068	3.951AspGly: 3.951 ± 0.085	1.167AspHis: 1.167 ± 0.035	4.183AspIle: 4.183 ± 0.066	4.005AspLys: 4.005 ± 0.085	5.408AspLeu: 5.408 ± 0.079	1.175AspMet: 1.175 ± 0.037	3.187AspAsn: 3.187 ± 0.092	2.25AspPro: 2.25 ± 0.057	2.282AspGln: 2.282 ± 0.057	2.478AspArg: 2.478 ± 0.054	4.58AspSer: 4.58 ± 0.122	3.576AspThr: 3.576 ± 0.113	3.845AspVal: 3.845 ± 0.066	0.753AspTrp: 0.753 ± 0.033	2.866AspTyr: 2.866 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	4.077GluAla: 4.077 ± 0.096	0.358GluCys: 0.358 ± 0.02	3.674GluAsp: 3.674 ± 0.073	5.457GluGlu: 5.457 ± 0.119	3.194GluPhe: 3.194 ± 0.068	3.912GluGly: 3.912 ± 0.079	1.236GluHis: 1.236 ± 0.044	5.165GluIle: 5.165 ± 0.075	6.484GluLys: 6.484 ± 0.12	6.805GluLeu: 6.805 ± 0.111	1.824GluMet: 1.824 ± 0.05	4.469GluAsn: 4.469 ± 0.079	2.103GluPro: 2.103 ± 0.047	2.599GluGln: 2.599 ± 0.068	2.969GluArg: 2.969 ± 0.067	4.01GluSer: 4.01 ± 0.071	3.312GluThr: 3.312 ± 0.071	4.84GluVal: 4.84 ± 0.076	0.729GluTrp: 0.729 ± 0.028	2.717GluTyr: 2.717 ± 0.066	0.0GluXaa: 0.0 ± 0.0
Phe	2.817PheAla: 2.817 ± 0.056	0.388PheCys: 0.388 ± 0.021	3.453PheAsp: 3.453 ± 0.066	3.699PheGlu: 3.699 ± 0.07	2.56PhePhe: 2.56 ± 0.07	3.526PheGly: 3.526 ± 0.066	0.932PheHis: 0.932 ± 0.033	3.649PheIle: 3.649 ± 0.071	3.22PheLys: 3.22 ± 0.061	4.134PheLeu: 4.134 ± 0.079	1.056PheMet: 1.056 ± 0.034	3.002PheAsn: 3.002 ± 0.063	1.61PhePro: 1.61 ± 0.04	1.593PheGln: 1.593 ± 0.043	1.807PheArg: 1.807 ± 0.044	4.043PheSer: 4.043 ± 0.083	3.098PheThr: 3.098 ± 0.056	2.937PheVal: 2.937 ± 0.066	0.609PheTrp: 0.609 ± 0.024	2.184PheTyr: 2.184 ± 0.052	0.0PheXaa: 0.0 ± 0.0
Gly	4.141GlyAla: 4.141 ± 0.094	0.818GlyCys: 0.818 ± 0.067	3.95GlyAsp: 3.95 ± 0.083	4.214GlyGlu: 4.214 ± 0.073	3.543GlyPhe: 3.543 ± 0.068	4.921GlyGly: 4.921 ± 0.114	1.176GlyHis: 1.176 ± 0.039	4.728GlyIle: 4.728 ± 0.08	4.66GlyLys: 4.66 ± 0.09	5.471GlyLeu: 5.471 ± 0.091	1.679GlyMet: 1.679 ± 0.044	4.036GlyAsn: 4.036 ± 0.11	1.636GlyPro: 1.636 ± 0.051	2.467GlyGln: 2.467 ± 0.059	2.191GlyArg: 2.191 ± 0.048	5.275GlySer: 5.275 ± 0.118	3.874GlyThr: 3.874 ± 0.095	4.685GlyVal: 4.685 ± 0.071	0.744GlyTrp: 0.744 ± 0.033	2.835GlyTyr: 2.835 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	0.927HisAla: 0.927 ± 0.034	0.181HisCys: 0.181 ± 0.015	1.021HisAsp: 1.021 ± 0.03	1.198HisGlu: 1.198 ± 0.036	1.131HisPhe: 1.131 ± 0.036	1.116HisGly: 1.116 ± 0.034	0.534HisHis: 0.534 ± 0.027	1.28HisIle: 1.28 ± 0.039	1.16HisLys: 1.16 ± 0.044	1.706HisLeu: 1.706 ± 0.049	0.331HisMet: 0.331 ± 0.019	1.007HisAsn: 1.007 ± 0.032	0.915HisPro: 0.915 ± 0.038	0.671HisGln: 0.671 ± 0.028	0.764HisArg: 0.764 ± 0.028	1.077HisSer: 1.077 ± 0.037	0.849HisThr: 0.849 ± 0.027	1.027HisVal: 1.027 ± 0.036	0.203HisTrp: 0.203 ± 0.017	1.005HisTyr: 1.005 ± 0.036	0.0HisXaa: 0.0 ± 0.0
Ile	4.863IleAla: 4.863 ± 0.08	0.593IleCys: 0.593 ± 0.026	5.163IleAsp: 5.163 ± 0.083	5.666IleGlu: 5.666 ± 0.078	2.974IlePhe: 2.974 ± 0.067	4.76IleGly: 4.76 ± 0.073	1.323IleHis: 1.323 ± 0.046	4.828IleIle: 4.828 ± 0.097	4.628IleLys: 4.628 ± 0.088	5.975IleLeu: 5.975 ± 0.105	1.366IleMet: 1.366 ± 0.037	4.07IleAsn: 4.07 ± 0.066	2.96IlePro: 2.96 ± 0.055	2.54IleGln: 2.54 ± 0.061	2.602IleArg: 2.602 ± 0.05	5.235IleSer: 5.235 ± 0.079	4.27IleThr: 4.27 ± 0.08	4.322IleVal: 4.322 ± 0.072	0.673IleTrp: 0.673 ± 0.025	2.598IleTyr: 2.598 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.559LysAla: 4.559 ± 0.105	0.349LysCys: 0.349 ± 0.024	3.981LysAsp: 3.981 ± 0.079	5.869LysGlu: 5.869 ± 0.125	2.655LysPhe: 2.655 ± 0.055	4.241LysGly: 4.241 ± 0.085	1.243LysHis: 1.243 ± 0.039	4.802LysIle: 4.802 ± 0.091	6.206LysLys: 6.206 ± 0.119	6.296LysLeu: 6.296 ± 0.098	1.941LysMet: 1.941 ± 0.054	3.973LysAsn: 3.973 ± 0.072	2.583LysPro: 2.583 ± 0.059	2.445LysGln: 2.445 ± 0.058	3.368LysArg: 3.368 ± 0.065	4.459LysSer: 4.459 ± 0.086	3.723LysThr: 3.723 ± 0.071	4.583LysVal: 4.583 ± 0.079	0.801LysTrp: 0.801 ± 0.028	2.609LysTyr: 2.609 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	5.386LeuAla: 5.386 ± 0.092	0.578LeuCys: 0.578 ± 0.042	5.235LeuAsp: 5.235 ± 0.078	5.789LeuGlu: 5.789 ± 0.1	4.579LeuPhe: 4.579 ± 0.081	5.339LeuGly: 5.339 ± 0.09	1.521LeuHis: 1.521 ± 0.05	6.544LeuIle: 6.544 ± 0.103	6.845LeuLys: 6.845 ± 0.114	8.007LeuLeu: 8.007 ± 0.143	1.956LeuMet: 1.956 ± 0.051	5.432LeuAsn: 5.432 ± 0.089	3.344LeuPro: 3.344 ± 0.064	2.859LeuGln: 2.859 ± 0.057	3.463LeuArg: 3.463 ± 0.068	6.823LeuSer: 6.823 ± 0.095	5.348LeuThr: 5.348 ± 0.075	5.082LeuVal: 5.082 ± 0.083	0.799LeuTrp: 0.799 ± 0.032	2.983LeuTyr: 2.983 ± 0.065	0.0LeuXaa: 0.0 ± 0.0
Met	1.571MetAla: 1.571 ± 0.047	0.124MetCys: 0.124 ± 0.011	1.233MetAsp: 1.233 ± 0.037	1.375MetGlu: 1.375 ± 0.042	0.805MetPhe: 0.805 ± 0.032	1.484MetGly: 1.484 ± 0.039	0.414MetHis: 0.414 ± 0.023	1.543MetIle: 1.543 ± 0.045	2.153MetLys: 2.153 ± 0.049	1.863MetLeu: 1.863 ± 0.042	0.571MetMet: 0.571 ± 0.027	1.317MetAsn: 1.317 ± 0.034	0.873MetPro: 0.873 ± 0.033	0.742MetGln: 0.742 ± 0.029	1.112MetArg: 1.112 ± 0.032	1.526MetSer: 1.526 ± 0.042	1.147MetThr: 1.147 ± 0.033	1.317MetVal: 1.317 ± 0.045	0.217MetTrp: 0.217 ± 0.014	0.638MetTyr: 0.638 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.518AsnAla: 3.518 ± 0.069	0.541AsnCys: 0.541 ± 0.029	3.565AsnAsp: 3.565 ± 0.078	3.902AsnGlu: 3.902 ± 0.065	2.753AsnPhe: 2.753 ± 0.063	4.55AsnGly: 4.55 ± 0.133	1.089AsnHis: 1.089 ± 0.037	4.114AsnIle: 4.114 ± 0.065	3.524AsnLys: 3.524 ± 0.08	4.878AsnLeu: 4.878 ± 0.076	1.123AsnMet: 1.123 ± 0.034	3.598AsnAsn: 3.598 ± 0.109	2.94AsnPro: 2.94 ± 0.081	2.292AsnGln: 2.292 ± 0.057	2.371AsnArg: 2.371 ± 0.056	4.061AsnSer: 4.061 ± 0.099	3.256AsnThr: 3.256 ± 0.082	3.369AsnVal: 3.369 ± 0.053	0.923AsnTrp: 0.923 ± 0.038	2.649AsnTyr: 2.649 ± 0.07	0.0AsnXaa: 0.0 ± 0.0
Pro	2.188ProAla: 2.188 ± 0.057	0.245ProCys: 0.245 ± 0.016	2.611ProAsp: 2.611 ± 0.06	2.723ProGlu: 2.723 ± 0.059	1.983ProPhe: 1.983 ± 0.043	2.432ProGly: 2.432 ± 0.054	0.673ProHis: 0.673 ± 0.03	2.378ProIle: 2.378 ± 0.049	2.224ProLys: 2.224 ± 0.055	2.751ProLeu: 2.751 ± 0.056	0.706ProMet: 0.706 ± 0.033	2.38ProAsn: 2.38 ± 0.059	0.938ProPro: 0.938 ± 0.039	1.474ProGln: 1.474 ± 0.05	1.075ProArg: 1.075 ± 0.037	2.375ProSer: 2.375 ± 0.054	1.966ProThr: 1.966 ± 0.042	2.766ProVal: 2.766 ± 0.052	0.333ProTrp: 0.333 ± 0.02	1.493ProTyr: 1.493 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	2.009GlnAla: 2.009 ± 0.061	0.185GlnCys: 0.185 ± 0.015	1.765GlnAsp: 1.765 ± 0.05	2.213GlnGlu: 2.213 ± 0.057	1.889GlnPhe: 1.889 ± 0.048	1.906GlnGly: 1.906 ± 0.044	0.64GlnHis: 0.64 ± 0.027	2.671GlnIle: 2.671 ± 0.061	2.866GlnLys: 2.866 ± 0.07	3.567GlnLeu: 3.567 ± 0.067	0.86GlnMet: 0.86 ± 0.033	2.708GlnAsn: 2.708 ± 0.07	1.275GlnPro: 1.275 ± 0.039	1.537GlnGln: 1.537 ± 0.052	1.455GlnArg: 1.455 ± 0.044	2.619GlnSer: 2.619 ± 0.056	1.875GlnThr: 1.875 ± 0.056	2.159GlnVal: 2.159 ± 0.05	0.38GlnTrp: 0.38 ± 0.023	1.465GlnTyr: 1.465 ± 0.044	0.0GlnXaa: 0.0 ± 0.0
Arg	2.267ArgAla: 2.267 ± 0.051	0.218ArgCys: 0.218 ± 0.016	2.288ArgAsp: 2.288 ± 0.052	2.972ArgGlu: 2.972 ± 0.063	2.149ArgPhe: 2.149 ± 0.054	2.215ArgGly: 2.215 ± 0.053	0.68ArgHis: 0.68 ± 0.027	3.02ArgIle: 3.02 ± 0.062	3.162ArgLys: 3.162 ± 0.066	3.447ArgLeu: 3.447 ± 0.07	0.988ArgMet: 0.988 ± 0.033	2.221ArgAsn: 2.221 ± 0.049	1.166ArgPro: 1.166 ± 0.035	1.323ArgGln: 1.323 ± 0.044	1.4ArgArg: 1.4 ± 0.042	2.471ArgSer: 2.471 ± 0.053	1.901ArgThr: 1.901 ± 0.046	2.573ArgVal: 2.573 ± 0.06	0.431ArgTrp: 0.431 ± 0.025	1.815ArgTyr: 1.815 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	4.266SerAla: 4.266 ± 0.092	0.705SerCys: 0.705 ± 0.041	4.416SerAsp: 4.416 ± 0.078	4.266SerGlu: 4.266 ± 0.077	4.158SerPhe: 4.158 ± 0.079	5.585SerGly: 5.585 ± 0.139	1.115SerHis: 1.115 ± 0.037	5.344SerIle: 5.344 ± 0.086	4.388SerLys: 4.388 ± 0.082	6.328SerLeu: 6.328 ± 0.092	1.464SerMet: 1.464 ± 0.041	4.085SerAsn: 4.085 ± 0.094	2.459SerPro: 2.459 ± 0.062	2.579SerGln: 2.579 ± 0.058	2.369SerArg: 2.369 ± 0.058	5.389SerSer: 5.389 ± 0.134	4.062SerThr: 4.062 ± 0.105	4.713SerVal: 4.713 ± 0.083	0.911SerTrp: 0.911 ± 0.035	2.856SerTyr: 2.856 ± 0.072	0.0SerXaa: 0.0 ± 0.0
Thr	3.735ThrAla: 3.735 ± 0.095	0.403ThrCys: 0.403 ± 0.023	3.434ThrAsp: 3.434 ± 0.089	3.27ThrGlu: 3.27 ± 0.064	2.856ThrPhe: 2.856 ± 0.062	4.518ThrGly: 4.518 ± 0.115	0.963ThrHis: 0.963 ± 0.032	4.425ThrIle: 4.425 ± 0.082	2.988ThrLys: 2.988 ± 0.059	4.98ThrLeu: 4.98 ± 0.084	0.967ThrMet: 0.967 ± 0.034	3.153ThrAsn: 3.153 ± 0.07	2.363ThrPro: 2.363 ± 0.059	1.814ThrGln: 1.814 ± 0.055	1.821ThrArg: 1.821 ± 0.044	3.874ThrSer: 3.874 ± 0.091	3.336ThrThr: 3.336 ± 0.101	4.223ThrVal: 4.223 ± 0.107	0.623ThrTrp: 0.623 ± 0.034	2.347ThrTyr: 2.347 ± 0.078	0.0ThrXaa: 0.0 ± 0.0
Val	3.82ValAla: 3.82 ± 0.07	0.556ValCys: 0.556 ± 0.038	4.026ValAsp: 4.026 ± 0.07	4.784ValGlu: 4.784 ± 0.076	3.321ValPhe: 3.321 ± 0.065	4.042ValGly: 4.042 ± 0.072	1.074ValHis: 1.074 ± 0.036	4.497ValIle: 4.497 ± 0.074	4.513ValLys: 4.513 ± 0.082	5.533ValLeu: 5.533 ± 0.091	1.344ValMet: 1.344 ± 0.044	3.711ValAsn: 3.711 ± 0.072	2.215ValPro: 2.215 ± 0.053	2.089ValGln: 2.089 ± 0.054	2.522ValArg: 2.522 ± 0.052	4.697ValSer: 4.697 ± 0.09	3.894ValThr: 3.894 ± 0.128	4.47ValVal: 4.47 ± 0.084	0.638ValTrp: 0.638 ± 0.026	2.58ValTyr: 2.58 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	0.582TrpAla: 0.582 ± 0.023	0.102TrpCys: 0.102 ± 0.01	0.717TrpAsp: 0.717 ± 0.032	0.702TrpGlu: 0.702 ± 0.026	0.576TrpPhe: 0.576 ± 0.025	0.641TrpGly: 0.641 ± 0.028	0.239TrpHis: 0.239 ± 0.017	0.757TrpIle: 0.757 ± 0.027	0.807TrpLys: 0.807 ± 0.029	1.023TrpLeu: 1.023 ± 0.034	0.298TrpMet: 0.298 ± 0.016	0.751TrpAsn: 0.751 ± 0.036	0.264TrpPro: 0.264 ± 0.018	0.438TrpGln: 0.438 ± 0.028	0.46TrpArg: 0.46 ± 0.021	0.894TrpSer: 0.894 ± 0.048	0.556TrpThr: 0.556 ± 0.03	0.681TrpVal: 0.681 ± 0.033	0.144TrpTrp: 0.144 ± 0.012	0.472TrpTyr: 0.472 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.292TyrAla: 2.292 ± 0.052	0.36TyrCys: 0.36 ± 0.02	2.76TyrAsp: 2.76 ± 0.06	2.556TyrGlu: 2.556 ± 0.062	2.305TyrPhe: 2.305 ± 0.047	2.652TyrGly: 2.652 ± 0.061	0.812TyrHis: 0.812 ± 0.032	2.362TyrIle: 2.362 ± 0.056	2.423TyrLys: 2.423 ± 0.051	3.628TyrLeu: 3.628 ± 0.061	0.78TyrMet: 0.78 ± 0.028	2.386TyrAsn: 2.386 ± 0.061	1.621TyrPro: 1.621 ± 0.041	1.525TyrGln: 1.525 ± 0.037	1.996TyrArg: 1.996 ± 0.051	3.277TyrSer: 3.277 ± 0.076	2.304TyrThr: 2.304 ± 0.068	2.157TyrVal: 2.157 ± 0.051	0.546TyrTrp: 0.546 ± 0.025	1.989TyrTyr: 1.989 ± 0.067	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2675 proteins (957364 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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