Amino acid dipepetide frequency for Cercopithecine herpesvirus 9 (strain DHV) (CeHV-9) (Simian varicella virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.066AlaAla: 5.066 ± 0.604
1.775AlaCys: 1.775 ± 0.196
2.662AlaAsp: 2.662 ± 0.193
2.891AlaGlu: 2.891 ± 0.258
2.977AlaPhe: 2.977 ± 0.281
2.891AlaGly: 2.891 ± 0.414
1.746AlaHis: 1.746 ± 0.208
4.293AlaIle: 4.293 ± 0.371
1.889AlaLys: 1.889 ± 0.217
7.156AlaLeu: 7.156 ± 0.476
1.46AlaMet: 1.46 ± 0.176
2.891AlaAsn: 2.891 ± 0.357
3.378AlaPro: 3.378 ± 0.392
1.889AlaGln: 1.889 ± 0.257
3.778AlaArg: 3.778 ± 0.485
4.465AlaSer: 4.465 ± 0.353
4.15AlaThr: 4.15 ± 0.285
5.581AlaVal: 5.581 ± 0.502
0.716AlaTrp: 0.716 ± 0.137
2.977AlaTyr: 2.977 ± 0.305
0.0AlaXaa: 0.0 ± 0.0
Cys
1.488CysAla: 1.488 ± 0.218
0.63CysCys: 0.63 ± 0.149
1.345CysAsp: 1.345 ± 0.225
1.403CysGlu: 1.403 ± 0.199
1.088CysPhe: 1.088 ± 0.17
1.403CysGly: 1.403 ± 0.275
0.572CysHis: 0.572 ± 0.122
1.946CysIle: 1.946 ± 0.262
1.488CysLys: 1.488 ± 0.207
2.605CysLeu: 2.605 ± 0.284
0.487CysMet: 0.487 ± 0.118
1.689CysAsn: 1.689 ± 0.286
0.773CysPro: 0.773 ± 0.144
0.658CysGln: 0.658 ± 0.109
0.973CysArg: 0.973 ± 0.191
1.832CysSer: 1.832 ± 0.256
1.517CysThr: 1.517 ± 0.262
2.032CysVal: 2.032 ± 0.279
0.286CysTrp: 0.286 ± 0.1
1.03CysTyr: 1.03 ± 0.183
0.0CysXaa: 0.0 ± 0.0
Asp
3.378AspAla: 3.378 ± 0.288
0.973AspCys: 0.973 ± 0.18
2.776AspAsp: 2.776 ± 0.379
2.776AspGlu: 2.776 ± 0.229
2.061AspPhe: 2.061 ± 0.242
2.92AspGly: 2.92 ± 0.338
0.744AspHis: 0.744 ± 0.152
4.637AspIle: 4.637 ± 0.374
1.86AspLys: 1.86 ± 0.236
4.465AspLeu: 4.465 ± 0.398
1.202AspMet: 1.202 ± 0.179
2.347AspAsn: 2.347 ± 0.233
2.433AspPro: 2.433 ± 0.413
0.859AspGln: 0.859 ± 0.154
2.147AspArg: 2.147 ± 0.253
3.492AspSer: 3.492 ± 0.326
2.977AspThr: 2.977 ± 0.277
5.095AspVal: 5.095 ± 0.443
0.572AspTrp: 0.572 ± 0.123
1.403AspTyr: 1.403 ± 0.197
0.0AspXaa: 0.0 ± 0.0
Glu
3.664GluAla: 3.664 ± 0.296
1.259GluCys: 1.259 ± 0.206
2.862GluAsp: 2.862 ± 0.34
2.977GluGlu: 2.977 ± 0.393
1.832GluPhe: 1.832 ± 0.21
2.347GluGly: 2.347 ± 0.319
1.889GluHis: 1.889 ± 0.295
2.891GluIle: 2.891 ± 0.281
2.261GluLys: 2.261 ± 0.257
4.866GluLeu: 4.866 ± 0.369
0.916GluMet: 0.916 ± 0.182
3.578GluAsn: 3.578 ± 0.31
2.032GluPro: 2.032 ± 0.26
2.004GluGln: 2.004 ± 0.203
3.406GluArg: 3.406 ± 0.368
3.635GluSer: 3.635 ± 0.341
3.95GluThr: 3.95 ± 0.397
2.404GluVal: 2.404 ± 0.276
0.458GluTrp: 0.458 ± 0.11
1.946GluTyr: 1.946 ± 0.2
0.0GluXaa: 0.0 ± 0.0
Phe
2.147PheAla: 2.147 ± 0.258
0.859PheCys: 0.859 ± 0.186
2.318PheAsp: 2.318 ± 0.298
2.032PheGlu: 2.032 ± 0.288
2.061PhePhe: 2.061 ± 0.231
2.633PheGly: 2.633 ± 0.3
0.83PheHis: 0.83 ± 0.18
3.206PheIle: 3.206 ± 0.34
2.376PheLys: 2.376 ± 0.311
3.32PheLeu: 3.32 ± 0.351
1.317PheMet: 1.317 ± 0.172
2.376PheAsn: 2.376 ± 0.291
2.204PhePro: 2.204 ± 0.252
1.317PheGln: 1.317 ± 0.211
1.717PheArg: 1.717 ± 0.236
3.549PheSer: 3.549 ± 0.32
3.177PheThr: 3.177 ± 0.38
3.463PheVal: 3.463 ± 0.273
0.429PheTrp: 0.429 ± 0.109
1.803PheTyr: 1.803 ± 0.251
0.0PheXaa: 0.0 ± 0.0
Gly
3.492GlyAla: 3.492 ± 0.322
1.145GlyCys: 1.145 ± 0.141
3.292GlyAsp: 3.292 ± 0.449
2.547GlyGlu: 2.547 ± 0.398
2.433GlyPhe: 2.433 ± 0.271
2.891GlyGly: 2.891 ± 0.366
0.973GlyHis: 0.973 ± 0.136
3.149GlyIle: 3.149 ± 0.234
2.118GlyLys: 2.118 ± 0.278
5.124GlyLeu: 5.124 ± 0.354
1.03GlyMet: 1.03 ± 0.185
2.29GlyAsn: 2.29 ± 0.24
2.605GlyPro: 2.605 ± 0.523
1.574GlyGln: 1.574 ± 0.229
2.891GlyArg: 2.891 ± 0.342
3.32GlySer: 3.32 ± 0.472
3.435GlyThr: 3.435 ± 0.353
3.921GlyVal: 3.921 ± 0.367
0.601GlyTrp: 0.601 ± 0.137
1.717GlyTyr: 1.717 ± 0.242
0.0GlyXaa: 0.0 ± 0.0
His
1.574HisAla: 1.574 ± 0.231
0.63HisCys: 0.63 ± 0.145
0.859HisAsp: 0.859 ± 0.188
1.174HisGlu: 1.174 ± 0.181
1.145HisPhe: 1.145 ± 0.166
1.946HisGly: 1.946 ± 0.247
0.83HisHis: 0.83 ± 0.169
2.004HisIle: 2.004 ± 0.235
1.202HisLys: 1.202 ± 0.153
2.118HisLeu: 2.118 ± 0.211
0.801HisMet: 0.801 ± 0.157
1.488HisAsn: 1.488 ± 0.219
1.46HisPro: 1.46 ± 0.202
0.744HisGln: 0.744 ± 0.165
1.717HisArg: 1.717 ± 0.258
2.061HisSer: 2.061 ± 0.249
1.603HisThr: 1.603 ± 0.223
2.118HisVal: 2.118 ± 0.278
0.143HisTrp: 0.143 ± 0.057
0.859HisTyr: 0.859 ± 0.14
0.0HisXaa: 0.0 ± 0.0
Ile
4.351IleAla: 4.351 ± 0.361
1.689IleCys: 1.689 ± 0.213
2.776IleAsp: 2.776 ± 0.293
3.292IleGlu: 3.292 ± 0.289
2.318IlePhe: 2.318 ± 0.313
2.547IleGly: 2.547 ± 0.239
1.746IleHis: 1.746 ± 0.27
4.093IleIle: 4.093 ± 0.382
2.748IleLys: 2.748 ± 0.258
5.066IleLeu: 5.066 ± 0.374
1.259IleMet: 1.259 ± 0.203
4.236IleAsn: 4.236 ± 0.338
3.664IlePro: 3.664 ± 0.27
3.378IleGln: 3.378 ± 0.328
3.12IleArg: 3.12 ± 0.29
6.268IleSer: 6.268 ± 0.577
5.381IleThr: 5.381 ± 0.457
3.807IleVal: 3.807 ± 0.334
0.83IleTrp: 0.83 ± 0.14
2.662IleTyr: 2.662 ± 0.286
0.0IleXaa: 0.0 ± 0.0
Lys
2.547LysAla: 2.547 ± 0.32
1.116LysCys: 1.116 ± 0.189
2.061LysAsp: 2.061 ± 0.227
1.775LysGlu: 1.775 ± 0.259
1.86LysPhe: 1.86 ± 0.247
1.431LysGly: 1.431 ± 0.171
1.86LysHis: 1.86 ± 0.266
2.376LysIle: 2.376 ± 0.27
1.86LysLys: 1.86 ± 0.307
4.265LysLeu: 4.265 ± 0.544
1.259LysMet: 1.259 ± 0.137
2.29LysAsn: 2.29 ± 0.296
2.233LysPro: 2.233 ± 0.231
2.147LysGln: 2.147 ± 0.252
3.349LysArg: 3.349 ± 0.381
2.633LysSer: 2.633 ± 0.347
3.234LysThr: 3.234 ± 0.284
2.032LysVal: 2.032 ± 0.297
0.286LysTrp: 0.286 ± 0.082
1.632LysTyr: 1.632 ± 0.225
0.0LysXaa: 0.0 ± 0.0
Leu
5.925LeuAla: 5.925 ± 0.456
2.92LeuCys: 2.92 ± 0.276
3.921LeuAsp: 3.921 ± 0.469
5.181LeuGlu: 5.181 ± 0.379
4.751LeuPhe: 4.751 ± 0.432
4.637LeuGly: 4.637 ± 0.248
2.805LeuHis: 2.805 ± 0.27
5.925LeuIle: 5.925 ± 0.527
4.179LeuLys: 4.179 ± 0.339
10.533LeuLeu: 10.533 ± 0.704
2.49LeuMet: 2.49 ± 0.285
5.209LeuAsn: 5.209 ± 0.509
5.038LeuPro: 5.038 ± 0.397
4.379LeuGln: 4.379 ± 0.341
5.152LeuArg: 5.152 ± 0.392
6.784LeuSer: 6.784 ± 0.416
6.44LeuThr: 6.44 ± 0.424
5.152LeuVal: 5.152 ± 0.467
1.202LeuTrp: 1.202 ± 0.188
3.95LeuTyr: 3.95 ± 0.345
0.0LeuXaa: 0.0 ± 0.0
Met
1.632MetAla: 1.632 ± 0.224
0.658MetCys: 0.658 ± 0.138
1.345MetAsp: 1.345 ± 0.223
1.775MetGlu: 1.775 ± 0.189
1.317MetPhe: 1.317 ± 0.244
1.145MetGly: 1.145 ± 0.187
0.601MetHis: 0.601 ± 0.112
0.687MetIle: 0.687 ± 0.152
0.63MetLys: 0.63 ± 0.131
2.547MetLeu: 2.547 ± 0.247
0.544MetMet: 0.544 ± 0.112
1.116MetAsn: 1.116 ± 0.177
0.773MetPro: 0.773 ± 0.124
0.744MetGln: 0.744 ± 0.153
1.059MetArg: 1.059 ± 0.14
2.004MetSer: 2.004 ± 0.197
1.059MetThr: 1.059 ± 0.17
1.002MetVal: 1.002 ± 0.173
0.544MetTrp: 0.544 ± 0.12
0.887MetTyr: 0.887 ± 0.149
0.0MetXaa: 0.0 ± 0.0
Asn
3.492AsnAla: 3.492 ± 0.354
1.03AsnCys: 1.03 ± 0.194
2.261AsnAsp: 2.261 ± 0.255
3.063AsnGlu: 3.063 ± 0.289
2.089AsnPhe: 2.089 ± 0.268
2.633AsnGly: 2.633 ± 0.258
1.116AsnHis: 1.116 ± 0.172
4.551AsnIle: 4.551 ± 0.512
2.233AsnLys: 2.233 ± 0.267
4.379AsnLeu: 4.379 ± 0.375
1.345AsnMet: 1.345 ± 0.176
3.206AsnAsn: 3.206 ± 0.298
2.605AsnPro: 2.605 ± 0.293
1.345AsnGln: 1.345 ± 0.199
2.605AsnArg: 2.605 ± 0.213
3.864AsnSer: 3.864 ± 0.376
4.608AsnThr: 4.608 ± 0.375
5.124AsnVal: 5.124 ± 0.315
0.487AsnTrp: 0.487 ± 0.107
1.889AsnTyr: 1.889 ± 0.239
0.0AsnXaa: 0.0 ± 0.0
Pro
2.633ProAla: 2.633 ± 0.455
1.174ProCys: 1.174 ± 0.179
3.091ProAsp: 3.091 ± 0.279
2.748ProGlu: 2.748 ± 0.32
1.918ProPhe: 1.918 ± 0.261
3.378ProGly: 3.378 ± 0.459
1.374ProHis: 1.374 ± 0.213
3.091ProIle: 3.091 ± 0.324
1.946ProLys: 1.946 ± 0.238
4.494ProLeu: 4.494 ± 0.424
0.83ProMet: 0.83 ± 0.171
2.204ProAsn: 2.204 ± 0.225
3.807ProPro: 3.807 ± 0.494
1.546ProGln: 1.546 ± 0.277
3.063ProArg: 3.063 ± 0.546
4.723ProSer: 4.723 ± 0.709
3.721ProThr: 3.721 ± 0.36
3.692ProVal: 3.692 ± 0.351
0.429ProTrp: 0.429 ± 0.111
1.374ProTyr: 1.374 ± 0.199
0.0ProXaa: 0.0 ± 0.0
Gln
2.29GlnAla: 2.29 ± 0.258
0.973GlnCys: 0.973 ± 0.138
1.259GlnAsp: 1.259 ± 0.173
1.546GlnGlu: 1.546 ± 0.226
1.603GlnPhe: 1.603 ± 0.254
1.603GlnGly: 1.603 ± 0.205
1.059GlnHis: 1.059 ± 0.184
1.775GlnIle: 1.775 ± 0.212
1.488GlnLys: 1.488 ± 0.261
3.864GlnLeu: 3.864 ± 0.357
0.716GlnMet: 0.716 ± 0.129
1.918GlnAsn: 1.918 ± 0.183
2.547GlnPro: 2.547 ± 0.536
1.689GlnGln: 1.689 ± 0.202
2.547GlnArg: 2.547 ± 0.313
2.748GlnSer: 2.748 ± 0.346
2.862GlnThr: 2.862 ± 0.245
1.746GlnVal: 1.746 ± 0.173
0.401GlnTrp: 0.401 ± 0.12
1.488GlnTyr: 1.488 ± 0.197
0.0GlnXaa: 0.0 ± 0.0
Arg
3.95ArgAla: 3.95 ± 0.475
1.288ArgCys: 1.288 ± 0.184
2.92ArgAsp: 2.92 ± 0.281
2.576ArgGlu: 2.576 ± 0.245
2.519ArgPhe: 2.519 ± 0.3
3.005ArgGly: 3.005 ± 0.407
1.403ArgHis: 1.403 ± 0.222
3.606ArgIle: 3.606 ± 0.333
2.433ArgLys: 2.433 ± 0.281
5.61ArgLeu: 5.61 ± 0.483
1.03ArgMet: 1.03 ± 0.196
2.49ArgAsn: 2.49 ± 0.294
2.433ArgPro: 2.433 ± 0.255
1.889ArgGln: 1.889 ± 0.206
4.494ArgArg: 4.494 ± 0.568
3.835ArgSer: 3.835 ± 0.459
3.034ArgThr: 3.034 ± 0.279
4.007ArgVal: 4.007 ± 0.342
0.286ArgTrp: 0.286 ± 0.126
2.032ArgTyr: 2.032 ± 0.303
0.0ArgXaa: 0.0 ± 0.0
Ser
4.723SerAla: 4.723 ± 0.457
1.86SerCys: 1.86 ± 0.208
3.893SerAsp: 3.893 ± 0.429
3.75SerGlu: 3.75 ± 0.362
2.662SerPhe: 2.662 ± 0.311
4.064SerGly: 4.064 ± 0.43
1.832SerHis: 1.832 ± 0.224
4.809SerIle: 4.809 ± 0.347
3.063SerLys: 3.063 ± 0.242
7.213SerLeu: 7.213 ± 0.452
1.145SerMet: 1.145 ± 0.206
4.494SerAsn: 4.494 ± 0.396
3.921SerPro: 3.921 ± 0.319
3.32SerGln: 3.32 ± 0.652
3.378SerArg: 3.378 ± 0.326
6.497SerSer: 6.497 ± 0.662
6.87SerThr: 6.87 ± 0.515
6.211SerVal: 6.211 ± 0.345
0.801SerTrp: 0.801 ± 0.165
2.576SerTyr: 2.576 ± 0.235
0.0SerXaa: 0.0 ± 0.0
Thr
5.181ThrAla: 5.181 ± 0.398
1.775ThrCys: 1.775 ± 0.219
3.349ThrAsp: 3.349 ± 0.284
4.15ThrGlu: 4.15 ± 0.331
2.834ThrPhe: 2.834 ± 0.276
3.664ThrGly: 3.664 ± 0.362
2.175ThrHis: 2.175 ± 0.283
3.95ThrIle: 3.95 ± 0.384
2.691ThrLys: 2.691 ± 0.249
7.127ThrLeu: 7.127 ± 0.554
1.03ThrMet: 1.03 ± 0.146
3.034ThrAsn: 3.034 ± 0.277
4.064ThrPro: 4.064 ± 0.307
3.063ThrGln: 3.063 ± 0.303
3.75ThrArg: 3.75 ± 0.272
6.87ThrSer: 6.87 ± 0.525
4.494ThrThr: 4.494 ± 0.379
4.809ThrVal: 4.809 ± 0.395
0.859ThrTrp: 0.859 ± 0.193
2.719ThrTyr: 2.719 ± 0.35
0.0ThrXaa: 0.0 ± 0.0
Val
4.093ValAla: 4.093 ± 0.388
2.233ValCys: 2.233 ± 0.294
3.893ValAsp: 3.893 ± 0.317
3.292ValGlu: 3.292 ± 0.292
3.435ValPhe: 3.435 ± 0.362
2.862ValGly: 2.862 ± 0.365
1.717ValHis: 1.717 ± 0.235
4.723ValIle: 4.723 ± 0.403
3.206ValLys: 3.206 ± 0.291
7.385ValLeu: 7.385 ± 0.409
1.918ValMet: 1.918 ± 0.278
4.179ValAsn: 4.179 ± 0.347
3.12ValPro: 3.12 ± 0.24
2.347ValGln: 2.347 ± 0.235
3.435ValArg: 3.435 ± 0.284
4.923ValSer: 4.923 ± 0.374
5.038ValThr: 5.038 ± 0.434
3.921ValVal: 3.921 ± 0.318
0.372ValTrp: 0.372 ± 0.093
3.721ValTyr: 3.721 ± 0.312
0.0ValXaa: 0.0 ± 0.0
Trp
0.687TrpAla: 0.687 ± 0.116
0.229TrpCys: 0.229 ± 0.077
0.429TrpAsp: 0.429 ± 0.106
0.372TrpGlu: 0.372 ± 0.081
0.544TrpPhe: 0.544 ± 0.111
0.572TrpGly: 0.572 ± 0.122
0.401TrpHis: 0.401 ± 0.095
0.429TrpIle: 0.429 ± 0.105
0.544TrpLys: 0.544 ± 0.12
1.002TrpLeu: 1.002 ± 0.15
0.315TrpMet: 0.315 ± 0.114
0.658TrpAsn: 0.658 ± 0.129
0.687TrpPro: 0.687 ± 0.168
0.343TrpGln: 0.343 ± 0.113
0.515TrpArg: 0.515 ± 0.122
0.687TrpSer: 0.687 ± 0.13
1.088TrpThr: 1.088 ± 0.214
0.458TrpVal: 0.458 ± 0.11
0.114TrpTrp: 0.114 ± 0.054
0.258TrpTyr: 0.258 ± 0.084
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.318TyrAla: 2.318 ± 0.249
1.03TyrCys: 1.03 ± 0.151
1.832TyrAsp: 1.832 ± 0.242
1.86TyrGlu: 1.86 ± 0.274
1.689TyrPhe: 1.689 ± 0.219
1.975TyrGly: 1.975 ± 0.181
0.801TyrHis: 0.801 ± 0.145
3.091TyrIle: 3.091 ± 0.323
2.032TyrLys: 2.032 ± 0.278
3.435TyrLeu: 3.435 ± 0.266
0.945TyrMet: 0.945 ± 0.18
2.233TyrAsn: 2.233 ± 0.271
1.46TyrPro: 1.46 ± 0.204
0.887TyrGln: 0.887 ± 0.158
1.746TyrArg: 1.746 ± 0.2
2.891TyrSer: 2.891 ± 0.246
2.948TyrThr: 2.948 ± 0.349
3.234TyrVal: 3.234 ± 0.302
0.515TyrTrp: 0.515 ± 0.097
1.689TyrTyr: 1.689 ± 0.243
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 69 proteins (34938 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski