Amino acid dipepetide frequency for Stegodyphus mimosarum (African social velvet spider)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.711AlaAla: 4.711 ± 0.056	1.305AlaCys: 1.305 ± 0.015	3.095AlaAsp: 3.095 ± 0.043	3.653AlaGlu: 3.653 ± 0.037	2.41AlaPhe: 2.41 ± 0.019	3.139AlaGly: 3.139 ± 0.071	1.226AlaHis: 1.226 ± 0.014	3.227AlaIle: 3.227 ± 0.022	3.437AlaLys: 3.437 ± 0.03	5.262AlaLeu: 5.262 ± 0.042	1.404AlaMet: 1.404 ± 0.014	2.439AlaAsn: 2.439 ± 0.023	2.364AlaPro: 2.364 ± 0.026	2.152AlaGln: 2.152 ± 0.021	3.79AlaArg: 3.79 ± 0.038	5.223AlaSer: 5.223 ± 0.045	3.33AlaThr: 3.33 ± 0.024	4.514AlaVal: 4.514 ± 0.028	0.65AlaTrp: 0.65 ± 0.013	1.747AlaTyr: 1.747 ± 0.017	0.001AlaXaa: 0.001 ± 0.0
Cys	1.228CysAla: 1.228 ± 0.014	0.595CysCys: 0.595 ± 0.014	1.402CysAsp: 1.402 ± 0.021	1.6CysGlu: 1.6 ± 0.03	0.917CysPhe: 0.917 ± 0.013	1.501CysGly: 1.501 ± 0.021	0.682CysHis: 0.682 ± 0.01	1.493CysIle: 1.493 ± 0.017	1.504CysLys: 1.504 ± 0.021	1.995CysLeu: 1.995 ± 0.019	0.485CysMet: 0.485 ± 0.008	1.348CysAsn: 1.348 ± 0.023	1.092CysPro: 1.092 ± 0.02	0.85CysGln: 0.85 ± 0.014	1.271CysArg: 1.271 ± 0.019	2.158CysSer: 2.158 ± 0.022	1.098CysThr: 1.098 ± 0.016	1.335CysVal: 1.335 ± 0.018	0.227CysTrp: 0.227 ± 0.006	0.658CysTyr: 0.658 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	2.695AspAla: 2.695 ± 0.045	1.085AspCys: 1.085 ± 0.017	3.553AspAsp: 3.553 ± 0.033	4.386AspGlu: 4.386 ± 0.029	2.267AspPhe: 2.267 ± 0.02	2.975AspGly: 2.975 ± 0.026	1.374AspHis: 1.374 ± 0.015	3.565AspIle: 3.565 ± 0.024	2.996AspLys: 2.996 ± 0.024	4.599AspLeu: 4.599 ± 0.029	1.385AspMet: 1.385 ± 0.012	2.536AspAsn: 2.536 ± 0.018	2.299AspPro: 2.299 ± 0.021	1.539AspGln: 1.539 ± 0.019	2.54AspArg: 2.54 ± 0.026	4.219AspSer: 4.219 ± 0.032	2.386AspThr: 2.386 ± 0.021	3.523AspVal: 3.523 ± 0.023	0.881AspTrp: 0.881 ± 0.014	1.657AspTyr: 1.657 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	3.813GluAla: 3.813 ± 0.033	1.643GluCys: 1.643 ± 0.022	3.854GluAsp: 3.854 ± 0.029	5.869GluGlu: 5.869 ± 0.065	2.422GluPhe: 2.422 ± 0.02	2.774GluGly: 2.774 ± 0.027	1.7GluHis: 1.7 ± 0.016	4.006GluIle: 4.006 ± 0.033	5.784GluLys: 5.784 ± 0.05	5.411GluLeu: 5.411 ± 0.038	1.692GluMet: 1.692 ± 0.019	4.136GluAsn: 4.136 ± 0.029	2.109GluPro: 2.109 ± 0.021	2.379GluGln: 2.379 ± 0.024	3.663GluArg: 3.663 ± 0.029	4.808GluSer: 4.808 ± 0.036	3.513GluThr: 3.513 ± 0.033	3.967GluVal: 3.967 ± 0.032	0.727GluTrp: 0.727 ± 0.011	1.783GluTyr: 1.783 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	2.265PheAla: 2.265 ± 0.021	1.007PheCys: 1.007 ± 0.015	1.949PheAsp: 1.949 ± 0.018	2.5PheGlu: 2.5 ± 0.02	1.94PhePhe: 1.94 ± 0.018	2.164PheGly: 2.164 ± 0.021	1.101PheHis: 1.101 ± 0.014	2.332PheIle: 2.332 ± 0.021	2.274PheLys: 2.274 ± 0.019	4.09PheLeu: 4.09 ± 0.028	0.97PheMet: 0.97 ± 0.012	1.891PheAsn: 1.891 ± 0.015	1.858PhePro: 1.858 ± 0.017	1.88PheGln: 1.88 ± 0.016	2.101PheArg: 2.101 ± 0.019	3.921PheSer: 3.921 ± 0.028	2.194PheThr: 2.194 ± 0.022	2.386PheVal: 2.386 ± 0.019	0.461PheTrp: 0.461 ± 0.009	1.338PheTyr: 1.338 ± 0.015	0.001PheXaa: 0.001 ± 0.0
Gly	3.114GlyAla: 3.114 ± 0.072	1.01GlyCys: 1.01 ± 0.018	2.417GlyAsp: 2.417 ± 0.018	3.193GlyGlu: 3.193 ± 0.025	2.112GlyPhe: 2.112 ± 0.017	3.226GlyGly: 3.226 ± 0.053	1.388GlyHis: 1.388 ± 0.027	3.055GlyIle: 3.055 ± 0.026	3.367GlyLys: 3.367 ± 0.03	4.383GlyLeu: 4.383 ± 0.038	1.278GlyMet: 1.278 ± 0.017	2.592GlyAsn: 2.592 ± 0.02	2.124GlyPro: 2.124 ± 0.03	1.741GlyGln: 1.741 ± 0.024	3.294GlyArg: 3.294 ± 0.028	4.355GlySer: 4.355 ± 0.032	2.812GlyThr: 2.812 ± 0.026	3.092GlyVal: 3.092 ± 0.031	0.547GlyTrp: 0.547 ± 0.01	1.827GlyTyr: 1.827 ± 0.026	0.001GlyXaa: 0.001 ± 0.0
His	1.187HisAla: 1.187 ± 0.015	0.634HisCys: 0.634 ± 0.01	1.349HisAsp: 1.349 ± 0.017	1.291HisGlu: 1.291 ± 0.015	1.134HisPhe: 1.134 ± 0.013	1.272HisGly: 1.272 ± 0.028	1.039HisHis: 1.039 ± 0.04	1.617HisIle: 1.617 ± 0.018	1.472HisLys: 1.472 ± 0.02	2.953HisLeu: 2.953 ± 0.022	0.985HisMet: 0.985 ± 0.022	1.079HisAsn: 1.079 ± 0.014	1.35HisPro: 1.35 ± 0.017	1.065HisGln: 1.065 ± 0.014	1.933HisArg: 1.933 ± 0.02	2.349HisSer: 2.349 ± 0.02	1.882HisThr: 1.882 ± 0.03	2.101HisVal: 2.101 ± 0.022	0.271HisTrp: 0.271 ± 0.006	0.814HisTyr: 0.814 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.587IleAla: 3.587 ± 0.024	1.578IleCys: 1.578 ± 0.018	2.693IleAsp: 2.693 ± 0.024	3.679IleGlu: 3.679 ± 0.027	2.417IlePhe: 2.417 ± 0.021	2.867IleGly: 2.867 ± 0.025	1.746IleHis: 1.746 ± 0.026	3.69IleIle: 3.69 ± 0.031	3.558IleLys: 3.558 ± 0.027	5.282IleLeu: 5.282 ± 0.031	1.273IleMet: 1.273 ± 0.014	2.573IleAsn: 2.573 ± 0.02	3.098IlePro: 3.098 ± 0.02	2.295IleGln: 2.295 ± 0.019	3.178IleArg: 3.178 ± 0.023	4.918IleSer: 4.918 ± 0.033	2.994IleThr: 2.994 ± 0.027	3.63IleVal: 3.63 ± 0.024	0.592IleTrp: 0.592 ± 0.01	1.717IleTyr: 1.717 ± 0.019	0.001IleXaa: 0.001 ± 0.0
Lys	3.468LysAla: 3.468 ± 0.027	1.578LysCys: 1.578 ± 0.019	3.501LysAsp: 3.501 ± 0.024	5.162LysGlu: 5.162 ± 0.055	2.36LysPhe: 2.36 ± 0.02	2.998LysGly: 2.998 ± 0.028	1.763LysHis: 1.763 ± 0.025	3.878LysIle: 3.878 ± 0.03	5.78LysLys: 5.78 ± 0.052	5.731LysLeu: 5.731 ± 0.039	1.66LysMet: 1.66 ± 0.015	3.515LysAsn: 3.515 ± 0.026	3.199LysPro: 3.199 ± 0.038	2.694LysGln: 2.694 ± 0.02	3.699LysArg: 3.699 ± 0.027	5.71LysSer: 5.71 ± 0.043	3.456LysThr: 3.456 ± 0.028	3.645LysVal: 3.645 ± 0.028	0.708LysTrp: 0.708 ± 0.011	2.187LysTyr: 2.187 ± 0.018	0.002LysXaa: 0.002 ± 0.0
Leu	5.25LeuAla: 5.25 ± 0.034	2.18LeuCys: 2.18 ± 0.018	4.23LeuAsp: 4.23 ± 0.029	5.742LeuGlu: 5.742 ± 0.042	3.347LeuPhe: 3.347 ± 0.026	4.071LeuGly: 4.071 ± 0.035	2.457LeuHis: 2.457 ± 0.021	4.557LeuIle: 4.557 ± 0.03	6.579LeuLys: 6.579 ± 0.047	8.83LeuLeu: 8.83 ± 0.052	1.994LeuMet: 1.994 ± 0.021	4.765LeuAsn: 4.765 ± 0.033	5.052LeuPro: 5.052 ± 0.03	4.976LeuGln: 4.976 ± 0.035	5.203LeuArg: 5.203 ± 0.033	7.28LeuSer: 7.28 ± 0.036	4.821LeuThr: 4.821 ± 0.029	4.645LeuVal: 4.645 ± 0.026	1.516LeuTrp: 1.516 ± 0.019	2.741LeuTyr: 2.741 ± 0.022	0.001LeuXaa: 0.001 ± 0.0
Met	1.659MetAla: 1.659 ± 0.015	0.61MetCys: 0.61 ± 0.012	1.372MetAsp: 1.372 ± 0.015	1.561MetGlu: 1.561 ± 0.016	0.985MetPhe: 0.985 ± 0.013	1.065MetGly: 1.065 ± 0.012	0.645MetHis: 0.645 ± 0.012	1.151MetIle: 1.151 ± 0.015	1.801MetLys: 1.801 ± 0.013	2.309MetLeu: 2.309 ± 0.022	0.62MetMet: 0.62 ± 0.013	1.134MetAsn: 1.134 ± 0.012	1.197MetPro: 1.197 ± 0.014	0.936MetGln: 0.936 ± 0.013	1.31MetArg: 1.31 ± 0.013	1.979MetSer: 1.979 ± 0.018	1.206MetThr: 1.206 ± 0.012	1.448MetVal: 1.448 ± 0.013	0.264MetTrp: 0.264 ± 0.006	0.715MetTyr: 0.715 ± 0.011	0.001MetXaa: 0.001 ± 0.0
Asn	2.874AsnAla: 2.874 ± 0.023	1.15AsnCys: 1.15 ± 0.015	2.304AsnAsp: 2.304 ± 0.021	3.136AsnGlu: 3.136 ± 0.025	2.143AsnPhe: 2.143 ± 0.019	2.581AsnGly: 2.581 ± 0.025	1.223AsnHis: 1.223 ± 0.011	3.356AsnIle: 3.356 ± 0.026	3.233AsnLys: 3.233 ± 0.03	4.757AsnLeu: 4.757 ± 0.025	1.178AsnMet: 1.178 ± 0.015	2.484AsnAsn: 2.484 ± 0.025	2.191AsnPro: 2.191 ± 0.02	1.954AsnGln: 1.954 ± 0.018	2.294AsnArg: 2.294 ± 0.019	4.589AsnSer: 4.589 ± 0.035	2.37AsnThr: 2.37 ± 0.02	3.172AsnVal: 3.172 ± 0.024	0.467AsnTrp: 0.467 ± 0.008	1.564AsnTyr: 1.564 ± 0.016	0.001AsnXaa: 0.001 ± 0.0
Pro	2.871ProAla: 2.871 ± 0.022	0.866ProCys: 0.866 ± 0.018	2.649ProAsp: 2.649 ± 0.021	3.532ProGlu: 3.532 ± 0.028	1.954ProPhe: 1.954 ± 0.017	2.768ProGly: 2.768 ± 0.04	1.576ProHis: 1.576 ± 0.021	2.338ProIle: 2.338 ± 0.02	2.757ProLys: 2.757 ± 0.032	4.096ProLeu: 4.096 ± 0.027	1.015ProMet: 1.015 ± 0.012	2.053ProAsn: 2.053 ± 0.019	3.61ProPro: 3.61 ± 0.043	1.944ProGln: 1.944 ± 0.022	2.559ProArg: 2.559 ± 0.021	4.201ProSer: 4.201 ± 0.035	2.486ProThr: 2.486 ± 0.027	3.374ProVal: 3.374 ± 0.027	0.67ProTrp: 0.67 ± 0.01	1.656ProTyr: 1.656 ± 0.019	0.001ProXaa: 0.001 ± 0.0
Gln	2.087GlnAla: 2.087 ± 0.021	0.977GlnCys: 0.977 ± 0.014	2.079GlnAsp: 2.079 ± 0.017	2.659GlnGlu: 2.659 ± 0.026	1.342GlnPhe: 1.342 ± 0.017	1.672GlnGly: 1.672 ± 0.021	1.404GlnHis: 1.404 ± 0.015	2.143GlnIle: 2.143 ± 0.017	2.949GlnLys: 2.949 ± 0.025	4.001GlnLeu: 4.001 ± 0.032	1.037GlnMet: 1.037 ± 0.015	2.338GlnAsn: 2.338 ± 0.02	1.92GlnPro: 1.92 ± 0.02	2.624GlnGln: 2.624 ± 0.05	2.28GlnArg: 2.28 ± 0.019	3.064GlnSer: 3.064 ± 0.029	2.003GlnThr: 2.003 ± 0.02	2.237GlnVal: 2.237 ± 0.021	0.779GlnTrp: 0.779 ± 0.013	1.21GlnTyr: 1.21 ± 0.014	0.001GlnXaa: 0.001 ± 0.0
Arg	3.185ArgAla: 3.185 ± 0.03	1.18ArgCys: 1.18 ± 0.015	2.803ArgAsp: 2.803 ± 0.03	3.218ArgGlu: 3.218 ± 0.024	2.158ArgPhe: 2.158 ± 0.018	2.466ArgGly: 2.466 ± 0.028	1.904ArgHis: 1.904 ± 0.022	3.609ArgIle: 3.609 ± 0.03	4.178ArgLys: 4.178 ± 0.028	5.027ArgLeu: 5.027 ± 0.036	1.436ArgMet: 1.436 ± 0.017	2.956ArgAsn: 2.956 ± 0.024	2.584ArgPro: 2.584 ± 0.022	2.237ArgGln: 2.237 ± 0.019	4.987ArgArg: 4.987 ± 0.049	4.059ArgSer: 4.059 ± 0.033	3.45ArgThr: 3.45 ± 0.032	2.917ArgVal: 2.917 ± 0.021	0.627ArgTrp: 0.627 ± 0.009	1.98ArgTyr: 1.98 ± 0.018	0.001ArgXaa: 0.001 ± 0.0
Ser	5.062SerAla: 5.062 ± 0.058	1.816SerCys: 1.816 ± 0.022	4.801SerAsp: 4.801 ± 0.036	5.368SerGlu: 5.368 ± 0.044	3.752SerPhe: 3.752 ± 0.033	4.768SerGly: 4.768 ± 0.035	2.052SerHis: 2.052 ± 0.021	4.33SerIle: 4.33 ± 0.028	5.096SerLys: 5.096 ± 0.035	7.448SerLeu: 7.448 ± 0.039	1.716SerMet: 1.716 ± 0.016	4.167SerAsn: 4.167 ± 0.032	4.689SerPro: 4.689 ± 0.05	3.356SerGln: 3.356 ± 0.032	4.543SerArg: 4.543 ± 0.034	9.932SerSer: 9.932 ± 0.081	4.759SerThr: 4.759 ± 0.037	5.285SerVal: 5.285 ± 0.031	0.883SerTrp: 0.883 ± 0.012	2.459SerTyr: 2.459 ± 0.021	0.002SerXaa: 0.002 ± 0.0
Thr	3.819ThrAla: 3.819 ± 0.027	1.283ThrCys: 1.283 ± 0.019	3.113ThrAsp: 3.113 ± 0.022	3.547ThrGlu: 3.547 ± 0.034	2.253ThrPhe: 2.253 ± 0.019	3.288ThrGly: 3.288 ± 0.031	1.409ThrHis: 1.409 ± 0.019	2.784ThrIle: 2.784 ± 0.023	3.082ThrLys: 3.082 ± 0.022	4.556ThrLeu: 4.556 ± 0.025	1.163ThrMet: 1.163 ± 0.013	2.262ThrAsn: 2.262 ± 0.021	3.016ThrPro: 3.016 ± 0.028	1.769ThrGln: 1.769 ± 0.019	2.347ThrArg: 2.347 ± 0.019	5.05ThrSer: 5.05 ± 0.041	3.386ThrThr: 3.386 ± 0.044	3.875ThrVal: 3.875 ± 0.03	0.567ThrTrp: 0.567 ± 0.009	1.559ThrTyr: 1.559 ± 0.017	0.001ThrXaa: 0.001 ± 0.0
Val	3.666ValAla: 3.666 ± 0.025	1.912ValCys: 1.912 ± 0.035	2.893ValAsp: 2.893 ± 0.023	3.558ValGlu: 3.558 ± 0.029	2.822ValPhe: 2.822 ± 0.02	2.75ValGly: 2.75 ± 0.028	1.607ValHis: 1.607 ± 0.014	3.667ValIle: 3.667 ± 0.023	4.018ValLys: 4.018 ± 0.03	5.611ValLeu: 5.611 ± 0.03	1.599ValMet: 1.599 ± 0.014	2.739ValAsn: 2.739 ± 0.022	3.168ValPro: 3.168 ± 0.023	2.632ValGln: 2.632 ± 0.019	3.196ValArg: 3.196 ± 0.019	5.02ValSer: 5.02 ± 0.033	3.696ValThr: 3.696 ± 0.03	3.83ValVal: 3.83 ± 0.029	1.259ValTrp: 1.259 ± 0.018	1.793ValTyr: 1.793 ± 0.015	0.001ValXaa: 0.001 ± 0.0
Trp	0.685TrpAla: 0.685 ± 0.011	0.292TrpCys: 0.292 ± 0.006	0.793TrpAsp: 0.793 ± 0.012	0.611TrpGlu: 0.611 ± 0.009	0.466TrpPhe: 0.466 ± 0.008	0.728TrpGly: 0.728 ± 0.009	0.299TrpHis: 0.299 ± 0.006	0.636TrpIle: 0.636 ± 0.011	1.007TrpLys: 1.007 ± 0.013	1.028TrpLeu: 1.028 ± 0.013	0.303TrpMet: 0.303 ± 0.006	0.594TrpAsn: 0.594 ± 0.01	0.668TrpPro: 0.668 ± 0.009	0.621TrpGln: 0.621 ± 0.009	0.878TrpArg: 0.878 ± 0.011	0.964TrpSer: 0.964 ± 0.013	0.791TrpThr: 0.791 ± 0.01	0.56TrpVal: 0.56 ± 0.009	0.165TrpTrp: 0.165 ± 0.005	0.502TrpTyr: 0.502 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.854TyrAla: 1.854 ± 0.017	0.738TyrCys: 0.738 ± 0.012	1.61TyrAsp: 1.61 ± 0.017	1.787TyrGlu: 1.787 ± 0.016	1.422TyrPhe: 1.422 ± 0.015	1.858TyrGly: 1.858 ± 0.025	1.183TyrHis: 1.183 ± 0.013	1.933TyrIle: 1.933 ± 0.016	1.818TyrLys: 1.818 ± 0.017	2.867TyrLeu: 2.867 ± 0.024	0.776TyrMet: 0.776 ± 0.012	1.417TyrAsn: 1.417 ± 0.014	1.388TyrPro: 1.388 ± 0.018	1.159TyrGln: 1.159 ± 0.015	1.894TyrArg: 1.894 ± 0.016	2.482TyrSer: 2.482 ± 0.02	1.494TyrThr: 1.494 ± 0.017	1.899TyrVal: 1.899 ± 0.019	0.33TyrTrp: 0.33 ± 0.007	1.105TyrTyr: 1.105 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.002XaaLys: 0.002 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.003XaaSer: 0.003 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.14XaaXaa: 0.14 ± 0.015

Statistics based on 27009 proteins (7704465 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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