Amino acid dipepetide frequency for Botrytis porri botybirnavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.843AlaAla: 10.843 ± 2.796
0.542AlaCys: 0.542 ± 0.011
5.693AlaAsp: 5.693 ± 0.431
7.59AlaGlu: 7.59 ± 0.208
1.084AlaPhe: 1.084 ± 0.344
6.235AlaGly: 6.235 ± 1.782
3.795AlaHis: 3.795 ± 0.655
4.608AlaIle: 4.608 ± 1.014
5.964AlaLys: 5.964 ± 1.226
7.59AlaLeu: 7.59 ± 0.526
2.711AlaMet: 2.711 ± 0.31
2.711AlaAsn: 2.711 ± 0.791
3.524AlaPro: 3.524 ± 0.844
6.777AlaGln: 6.777 ± 1.059
6.235AlaArg: 6.235 ± 0.053
6.777AlaSer: 6.777 ± 1.143
5.15AlaThr: 5.15 ± 0.658
7.861AlaVal: 7.861 ± 0.715
1.626AlaTrp: 1.626 ± 0.034
4.879AlaTyr: 4.879 ± 0.836
0.271AlaXaa: 0.271 ± 0.189
Cys
0.813CysAla: 0.813 ± 0.533
0.271CysCys: 0.271 ± 0.178
0.542CysAsp: 0.542 ± 0.011
0.0CysGlu: 0.0 ± 0.0
0.271CysPhe: 0.271 ± 0.178
1.084CysGly: 1.084 ± 0.39
0.542CysHis: 0.542 ± 0.378
0.542CysIle: 0.542 ± 0.378
0.813CysLys: 0.813 ± 0.166
1.626CysLeu: 1.626 ± 1.067
0.813CysMet: 0.813 ± 0.166
0.271CysAsn: 0.271 ± 0.189
0.813CysPro: 0.813 ± 0.533
0.0CysGln: 0.0 ± 0.0
0.542CysArg: 0.542 ± 0.356
0.813CysSer: 0.813 ± 0.567
1.355CysThr: 1.355 ± 0.522
0.271CysVal: 0.271 ± 0.178
0.271CysTrp: 0.271 ± 0.189
0.271CysTyr: 0.271 ± 0.178
0.0CysXaa: 0.0 ± 0.0
Asp
4.066AspAla: 4.066 ± 1.002
0.271AspCys: 0.271 ± 0.178
3.524AspAsp: 3.524 ± 0.844
4.337AspGlu: 4.337 ± 0.091
0.813AspPhe: 0.813 ± 0.2
2.44AspGly: 2.44 ± 0.235
1.626AspHis: 1.626 ± 0.768
1.898AspIle: 1.898 ± 0.223
2.711AspLys: 2.711 ± 0.791
4.879AspLeu: 4.879 ± 1.366
1.084AspMet: 1.084 ± 0.39
2.982AspAsn: 2.982 ± 0.613
1.898AspPro: 1.898 ± 0.59
2.169AspGln: 2.169 ± 0.779
4.608AspArg: 4.608 ± 1.188
2.982AspSer: 2.982 ± 0.855
3.253AspThr: 3.253 ± 0.068
2.44AspVal: 2.44 ± 0.132
1.084AspTrp: 1.084 ± 0.344
2.44AspTyr: 2.44 ± 0.499
0.0AspXaa: 0.0 ± 0.0
Glu
5.693GluAla: 5.693 ± 0.431
0.813GluCys: 0.813 ± 0.166
5.15GluAsp: 5.15 ± 0.81
8.946GluGlu: 8.946 ± 1.097
2.44GluPhe: 2.44 ± 0.235
4.066GluGly: 4.066 ± 0.832
1.626GluHis: 1.626 ± 0.7
2.982GluIle: 2.982 ± 0.488
4.608GluLys: 4.608 ± 0.087
4.066GluLeu: 4.066 ± 0.098
1.626GluMet: 1.626 ± 0.333
2.982GluAsn: 2.982 ± 0.121
2.44GluPro: 2.44 ± 0.235
3.524GluGln: 3.524 ± 0.477
4.337GluArg: 4.337 ± 0.458
2.711GluSer: 2.711 ± 0.677
2.169GluThr: 2.169 ± 0.412
4.879GluVal: 4.879 ± 0.836
1.355GluTrp: 1.355 ± 0.579
3.524GluTyr: 3.524 ± 0.477
0.0GluXaa: 0.0 ± 0.0
Phe
2.44PheAla: 2.44 ± 0.601
0.271PheCys: 0.271 ± 0.189
1.626PheAsp: 1.626 ± 0.768
1.898PheGlu: 1.898 ± 0.144
0.813PhePhe: 0.813 ± 0.2
1.626PheGly: 1.626 ± 0.768
0.0PheHis: 0.0 ± 0.0
0.271PheIle: 0.271 ± 0.178
2.169PheLys: 2.169 ± 0.045
1.355PheLeu: 1.355 ± 0.212
0.542PheMet: 0.542 ± 0.011
1.626PheAsn: 1.626 ± 0.333
1.626PhePro: 1.626 ± 0.034
1.355PheGln: 1.355 ± 0.522
0.813PheArg: 0.813 ± 0.2
1.626PheSer: 1.626 ± 0.333
1.626PheThr: 1.626 ± 0.034
0.542PheVal: 0.542 ± 0.011
0.271PheTrp: 0.271 ± 0.178
0.542PheTyr: 0.542 ± 0.011
0.0PheXaa: 0.0 ± 0.0
Gly
7.048GlyAla: 7.048 ± 0.881
0.813GlyCys: 0.813 ± 0.533
3.253GlyAsp: 3.253 ± 0.068
4.337GlyGlu: 4.337 ± 0.091
1.355GlyPhe: 1.355 ± 0.155
4.066GlyGly: 4.066 ± 1.002
1.084GlyHis: 1.084 ± 0.023
3.795GlyIle: 3.795 ± 1.18
2.44GlyLys: 2.44 ± 0.866
3.524GlyLeu: 3.524 ± 0.257
2.44GlyMet: 2.44 ± 0.132
2.44GlyAsn: 2.44 ± 0.499
3.253GlyPro: 3.253 ± 0.666
2.169GlyGln: 2.169 ± 0.689
3.795GlyArg: 3.795 ± 0.288
4.337GlySer: 4.337 ± 0.276
5.15GlyThr: 5.15 ± 1.025
3.795GlyVal: 3.795 ± 0.446
1.626GlyTrp: 1.626 ± 0.7
3.253GlyTyr: 3.253 ± 0.435
0.0GlyXaa: 0.0 ± 0.0
His
1.355HisAla: 1.355 ± 0.212
0.542HisCys: 0.542 ± 0.011
0.271HisAsp: 0.271 ± 0.189
0.542HisGlu: 0.542 ± 0.356
0.271HisPhe: 0.271 ± 0.189
1.355HisGly: 1.355 ± 0.155
0.542HisHis: 0.542 ± 0.356
1.626HisIle: 1.626 ± 0.401
1.084HisLys: 1.084 ± 0.023
2.44HisLeu: 2.44 ± 0.499
0.813HisMet: 0.813 ± 0.567
1.626HisAsn: 1.626 ± 0.401
1.355HisPro: 1.355 ± 0.212
0.542HisGln: 0.542 ± 0.356
1.084HisArg: 1.084 ± 0.344
1.626HisSer: 1.626 ± 0.333
1.626HisThr: 1.626 ± 0.034
1.084HisVal: 1.084 ± 0.39
0.542HisTrp: 0.542 ± 0.011
1.355HisTyr: 1.355 ± 0.579
0.0HisXaa: 0.0 ± 0.0
Ile
5.964IleAla: 5.964 ± 0.492
0.271IleCys: 0.271 ± 0.178
2.982IleAsp: 2.982 ± 0.246
2.44IleGlu: 2.44 ± 0.235
0.813IlePhe: 0.813 ± 0.567
2.44IleGly: 2.44 ± 0.235
0.813IleHis: 0.813 ± 0.2
2.44IleIle: 2.44 ± 0.968
4.066IleLys: 4.066 ± 1.002
3.795IleLeu: 3.795 ± 1.755
1.626IleMet: 1.626 ± 0.333
1.626IleAsn: 1.626 ± 0.034
2.44IlePro: 2.44 ± 0.601
0.813IleGln: 0.813 ± 0.2
1.898IleArg: 1.898 ± 0.878
2.982IleSer: 2.982 ± 0.98
2.44IleThr: 2.44 ± 0.132
2.44IleVal: 2.44 ± 0.235
0.542IleTrp: 0.542 ± 0.378
1.898IleTyr: 1.898 ± 0.144
0.0IleXaa: 0.0 ± 0.0
Lys
7.048LysAla: 7.048 ± 0.881
0.271LysCys: 0.271 ± 0.178
3.795LysAsp: 3.795 ± 1.547
3.524LysGlu: 3.524 ± 0.844
1.898LysPhe: 1.898 ± 0.223
4.879LysGly: 4.879 ± 0.632
1.626LysHis: 1.626 ± 0.034
1.898LysIle: 1.898 ± 0.144
3.795LysLys: 3.795 ± 0.288
3.253LysLeu: 3.253 ± 0.435
2.982LysMet: 2.982 ± 0.613
2.44LysAsn: 2.44 ± 0.235
2.982LysPro: 2.982 ± 0.613
1.898LysGln: 1.898 ± 0.511
2.711LysArg: 2.711 ± 0.31
3.524LysSer: 3.524 ± 0.624
2.982LysThr: 2.982 ± 0.488
4.337LysVal: 4.337 ± 0.643
1.626LysTrp: 1.626 ± 0.333
1.626LysTyr: 1.626 ± 0.034
0.0LysXaa: 0.0 ± 0.0
Leu
10.301LeuAla: 10.301 ± 1.316
1.898LeuCys: 1.898 ± 0.223
2.982LeuAsp: 2.982 ± 0.488
4.879LeuGlu: 4.879 ± 0.999
2.44LeuPhe: 2.44 ± 0.601
6.506LeuGly: 6.506 ± 1.332
1.626LeuHis: 1.626 ± 0.768
4.337LeuIle: 4.337 ± 0.643
3.524LeuLys: 3.524 ± 0.477
4.879LeuLeu: 4.879 ± 0.469
2.711LeuMet: 2.711 ± 0.424
2.169LeuAsn: 2.169 ± 0.689
3.253LeuPro: 3.253 ± 0.299
2.711LeuGln: 2.711 ± 0.31
4.608LeuArg: 4.608 ± 0.087
5.693LeuSer: 5.693 ± 1.037
4.879LeuThr: 4.879 ± 0.632
4.337LeuVal: 4.337 ± 0.091
2.711LeuTrp: 2.711 ± 0.057
3.524LeuTyr: 3.524 ± 0.11
0.0LeuXaa: 0.0 ± 0.0
Met
2.982MetAla: 2.982 ± 0.246
0.0MetCys: 0.0 ± 0.0
0.542MetAsp: 0.542 ± 0.011
1.084MetGlu: 1.084 ± 0.344
1.355MetPhe: 1.355 ± 0.212
2.44MetGly: 2.44 ± 0.601
0.813MetHis: 0.813 ± 0.2
2.711MetIle: 2.711 ± 0.424
1.898MetLys: 1.898 ± 0.144
4.608MetLeu: 4.608 ± 1.381
0.813MetMet: 0.813 ± 0.166
0.813MetAsn: 0.813 ± 0.166
1.898MetPro: 1.898 ± 0.144
0.813MetGln: 0.813 ± 0.166
2.169MetArg: 2.169 ± 0.689
2.44MetSer: 2.44 ± 0.499
2.169MetThr: 2.169 ± 0.412
1.626MetVal: 1.626 ± 0.034
0.271MetTrp: 0.271 ± 0.178
1.898MetTyr: 1.898 ± 0.144
0.0MetXaa: 0.0 ± 0.0
Asn
2.982AsnAla: 2.982 ± 0.98
0.542AsnCys: 0.542 ± 0.356
1.355AsnAsp: 1.355 ± 0.155
1.898AsnGlu: 1.898 ± 0.223
0.271AsnPhe: 0.271 ± 0.189
2.169AsnGly: 2.169 ± 0.689
1.084AsnHis: 1.084 ± 0.39
1.084AsnIle: 1.084 ± 0.344
4.066AsnLys: 4.066 ± 0.269
3.795AsnLeu: 3.795 ± 0.446
0.542AsnMet: 0.542 ± 0.279
1.626AsnAsn: 1.626 ± 0.7
1.626AsnPro: 1.626 ± 0.333
0.813AsnGln: 0.813 ± 0.2
2.44AsnArg: 2.44 ± 0.132
3.795AsnSer: 3.795 ± 0.288
3.253AsnThr: 3.253 ± 0.802
3.524AsnVal: 3.524 ± 0.477
0.813AsnTrp: 0.813 ± 0.166
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.337ProAla: 4.337 ± 0.276
0.813ProCys: 0.813 ± 0.166
3.253ProAsp: 3.253 ± 0.666
2.711ProGlu: 2.711 ± 0.31
1.898ProPhe: 1.898 ± 0.223
1.898ProGly: 1.898 ± 0.223
0.813ProHis: 0.813 ± 0.166
1.355ProIle: 1.355 ± 0.155
3.524ProLys: 3.524 ± 0.257
2.982ProLeu: 2.982 ± 0.121
1.355ProMet: 1.355 ± 0.155
1.355ProAsn: 1.355 ± 0.212
1.626ProPro: 1.626 ± 0.333
1.084ProGln: 1.084 ± 0.023
1.355ProArg: 1.355 ± 0.579
2.711ProSer: 2.711 ± 0.791
5.15ProThr: 5.15 ± 1.025
5.693ProVal: 5.693 ± 1.165
0.271ProTrp: 0.271 ± 0.178
1.084ProTyr: 1.084 ± 0.344
0.0ProXaa: 0.0 ± 0.0
Gln
1.626GlnAla: 1.626 ± 0.034
0.813GlnCys: 0.813 ± 0.533
1.355GlnAsp: 1.355 ± 0.212
2.44GlnGlu: 2.44 ± 0.132
0.813GlnPhe: 0.813 ± 0.166
1.898GlnGly: 1.898 ± 0.223
1.626GlnHis: 1.626 ± 0.034
2.169GlnIle: 2.169 ± 0.045
1.355GlnLys: 1.355 ± 0.155
3.524GlnLeu: 3.524 ± 0.11
1.626GlnMet: 1.626 ± 0.034
1.084GlnAsn: 1.084 ± 0.39
2.711GlnPro: 2.711 ± 0.424
1.355GlnGln: 1.355 ± 0.889
2.982GlnArg: 2.982 ± 0.121
1.626GlnSer: 1.626 ± 0.401
2.711GlnThr: 2.711 ± 0.31
2.44GlnVal: 2.44 ± 1.233
1.084GlnTrp: 1.084 ± 0.344
1.626GlnTyr: 1.626 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
5.422ArgAla: 5.422 ± 0.254
0.542ArgCys: 0.542 ± 0.011
2.711ArgAsp: 2.711 ± 0.677
4.608ArgGlu: 4.608 ± 1.188
1.084ArgPhe: 1.084 ± 0.023
3.795ArgGly: 3.795 ± 0.655
0.542ArgHis: 0.542 ± 0.356
2.169ArgIle: 2.169 ± 0.322
3.253ArgLys: 3.253 ± 0.068
4.066ArgLeu: 4.066 ± 1.002
2.982ArgMet: 2.982 ± 0.246
0.813ArgAsn: 0.813 ± 0.533
2.169ArgPro: 2.169 ± 0.322
2.169ArgGln: 2.169 ± 0.322
2.711ArgArg: 2.711 ± 0.057
4.066ArgSer: 4.066 ± 0.832
2.44ArgThr: 2.44 ± 0.235
6.777ArgVal: 6.777 ± 1.059
1.355ArgTrp: 1.355 ± 0.522
3.253ArgTyr: 3.253 ± 0.068
0.0ArgXaa: 0.0 ± 0.0
Ser
7.59SerAla: 7.59 ± 0.893
0.813SerCys: 0.813 ± 0.166
2.982SerAsp: 2.982 ± 0.488
5.422SerGlu: 5.422 ± 0.847
1.898SerPhe: 1.898 ± 0.878
4.337SerGly: 4.337 ± 1.01
1.355SerHis: 1.355 ± 0.212
2.711SerIle: 2.711 ± 0.424
2.982SerLys: 2.982 ± 0.246
4.879SerLeu: 4.879 ± 0.102
1.898SerMet: 1.898 ± 0.59
2.711SerAsn: 2.711 ± 0.791
1.898SerPro: 1.898 ± 0.144
2.44SerGln: 2.44 ± 0.601
3.795SerArg: 3.795 ± 1.022
5.422SerSer: 5.422 ± 0.113
4.879SerThr: 4.879 ± 0.102
5.964SerVal: 5.964 ± 0.609
1.355SerTrp: 1.355 ± 0.212
1.626SerTyr: 1.626 ± 0.333
0.0SerXaa: 0.0 ± 0.0
Thr
7.59ThrAla: 7.59 ± 0.575
0.542ThrCys: 0.542 ± 0.011
4.066ThrAsp: 4.066 ± 1.002
3.253ThrGlu: 3.253 ± 0.435
1.355ThrPhe: 1.355 ± 0.212
4.066ThrGly: 4.066 ± 1.369
0.271ThrHis: 0.271 ± 0.189
3.524ThrIle: 3.524 ± 0.257
3.795ThrLys: 3.795 ± 0.288
5.693ThrLeu: 5.693 ± 1.037
2.169ThrMet: 2.169 ± 0.322
2.169ThrAsn: 2.169 ± 0.045
3.795ThrPro: 3.795 ± 0.288
1.898ThrGln: 1.898 ± 0.878
3.524ThrArg: 3.524 ± 0.991
4.337ThrSer: 4.337 ± 0.458
3.795ThrThr: 3.795 ± 0.288
4.337ThrVal: 4.337 ± 1.01
0.542ThrTrp: 0.542 ± 0.011
2.711ThrTyr: 2.711 ± 0.677
0.0ThrXaa: 0.0 ± 0.0
Val
8.403ValAla: 8.403 ± 0.008
1.084ValCys: 1.084 ± 0.39
2.44ValAsp: 2.44 ± 0.601
6.506ValGlu: 6.506 ± 0.965
1.355ValPhe: 1.355 ± 0.155
4.879ValGly: 4.879 ± 0.632
0.813ValHis: 0.813 ± 0.166
1.898ValIle: 1.898 ± 0.59
4.066ValLys: 4.066 ± 0.465
5.964ValLeu: 5.964 ± 0.976
2.44ValMet: 2.44 ± 0.235
2.44ValAsn: 2.44 ± 0.235
4.879ValPro: 4.879 ± 0.469
2.44ValGln: 2.44 ± 0.235
5.422ValArg: 5.422 ± 0.254
5.693ValSer: 5.693 ± 0.064
4.337ValThr: 4.337 ± 1.377
5.964ValVal: 5.964 ± 0.609
0.813ValTrp: 0.813 ± 0.2
1.626ValTyr: 1.626 ± 0.401
0.0ValXaa: 0.0 ± 0.0
Trp
2.44TrpAla: 2.44 ± 0.499
0.0TrpCys: 0.0 ± 0.0
1.626TrpAsp: 1.626 ± 0.401
1.084TrpGlu: 1.084 ± 0.39
0.542TrpPhe: 0.542 ± 0.011
1.084TrpGly: 1.084 ± 0.023
0.0TrpHis: 0.0 ± 0.0
1.084TrpIle: 1.084 ± 0.344
0.542TrpLys: 0.542 ± 0.011
2.169TrpLeu: 2.169 ± 0.689
1.084TrpMet: 1.084 ± 0.023
0.813TrpAsn: 0.813 ± 0.533
0.271TrpPro: 0.271 ± 0.189
0.813TrpGln: 0.813 ± 0.533
0.271TrpArg: 0.271 ± 0.178
1.626TrpSer: 1.626 ± 0.401
0.813TrpThr: 0.813 ± 0.567
1.084TrpVal: 1.084 ± 0.344
0.0TrpTrp: 0.0 ± 0.0
0.813TrpTyr: 0.813 ± 0.166
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.524TyrAla: 3.524 ± 0.11
0.813TyrCys: 0.813 ± 0.166
1.355TyrAsp: 1.355 ± 0.155
2.44TyrGlu: 2.44 ± 0.235
0.271TyrPhe: 0.271 ± 0.189
2.711TyrGly: 2.711 ± 0.31
1.084TyrHis: 1.084 ± 0.023
1.626TyrIle: 1.626 ± 0.333
2.44TyrLys: 2.44 ± 0.132
4.879TyrLeu: 4.879 ± 0.265
0.813TyrMet: 0.813 ± 0.126
3.253TyrAsn: 3.253 ± 0.666
0.813TyrPro: 0.813 ± 0.166
1.084TyrGln: 1.084 ± 0.39
1.355TyrArg: 1.355 ± 0.212
2.169TyrSer: 2.169 ± 0.412
3.253TyrThr: 3.253 ± 0.068
4.066TyrVal: 4.066 ± 0.269
0.0TyrTrp: 0.0 ± 0.0
1.355TyrTyr: 1.355 ± 0.155
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.271XaaArg: 0.271 ± 0.189
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3690 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski