Amino acid dipepetide frequency for Wheat yellow striate virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.9AlaAla: 5.9 ± 2.86
0.944AlaCys: 0.944 ± 0.264
4.956AlaAsp: 4.956 ± 0.741
2.596AlaGlu: 2.596 ± 0.997
1.888AlaPhe: 1.888 ± 0.854
4.248AlaGly: 4.248 ± 1.884
1.416AlaHis: 1.416 ± 0.391
2.596AlaIle: 2.596 ± 0.623
1.888AlaLys: 1.888 ± 0.569
4.72AlaLeu: 4.72 ± 0.731
0.708AlaMet: 0.708 ± 0.378
2.832AlaAsn: 2.832 ± 1.926
2.832AlaPro: 2.832 ± 1.595
2.124AlaGln: 2.124 ± 0.782
3.304AlaArg: 3.304 ± 1.087
3.54AlaSer: 3.54 ± 1.248
3.54AlaThr: 3.54 ± 1.235
2.36AlaVal: 2.36 ± 0.871
1.652AlaTrp: 1.652 ± 0.613
1.18AlaTyr: 1.18 ± 0.511
0.0AlaXaa: 0.0 ± 0.0
Cys
0.708CysAla: 0.708 ± 0.483
0.236CysCys: 0.236 ± 0.33
2.124CysAsp: 2.124 ± 0.844
0.708CysGlu: 0.708 ± 0.405
0.236CysPhe: 0.236 ± 0.268
0.236CysGly: 0.236 ± 0.303
0.708CysHis: 0.708 ± 0.459
1.652CysIle: 1.652 ± 0.857
0.708CysLys: 0.708 ± 0.337
1.18CysLeu: 1.18 ± 0.433
0.472CysMet: 0.472 ± 0.536
0.944CysAsn: 0.944 ± 0.593
0.708CysPro: 0.708 ± 0.298
0.236CysGln: 0.236 ± 0.268
0.708CysArg: 0.708 ± 0.29
2.124CysSer: 2.124 ± 0.577
0.708CysThr: 0.708 ± 0.249
0.236CysVal: 0.236 ± 0.268
0.236CysTrp: 0.236 ± 0.153
1.416CysTyr: 1.416 ± 0.723
0.0CysXaa: 0.0 ± 0.0
Asp
2.124AspAla: 2.124 ± 0.977
0.944AspCys: 0.944 ± 0.529
4.72AspAsp: 4.72 ± 0.864
5.192AspGlu: 5.192 ± 0.765
1.416AspPhe: 1.416 ± 0.605
4.956AspGly: 4.956 ± 0.647
0.944AspHis: 0.944 ± 0.613
4.956AspIle: 4.956 ± 0.989
2.36AspLys: 2.36 ± 0.543
5.428AspLeu: 5.428 ± 0.83
1.416AspMet: 1.416 ± 0.499
2.832AspAsn: 2.832 ± 0.638
2.36AspPro: 2.36 ± 0.821
1.416AspGln: 1.416 ± 0.922
2.124AspArg: 2.124 ± 0.872
2.832AspSer: 2.832 ± 0.795
6.136AspThr: 6.136 ± 2.603
5.428AspVal: 5.428 ± 0.981
0.944AspTrp: 0.944 ± 0.529
2.596AspTyr: 2.596 ± 0.984
0.0AspXaa: 0.0 ± 0.0
Glu
3.068GluAla: 3.068 ± 1.205
0.708GluCys: 0.708 ± 0.404
3.304GluAsp: 3.304 ± 1.155
5.428GluGlu: 5.428 ± 1.871
0.472GluPhe: 0.472 ± 0.345
4.248GluGly: 4.248 ± 1.084
0.944GluHis: 0.944 ± 0.823
4.248GluIle: 4.248 ± 1.316
4.012GluLys: 4.012 ± 0.672
5.428GluLeu: 5.428 ± 1.592
2.36GluMet: 2.36 ± 0.387
2.596GluAsn: 2.596 ± 0.524
2.124GluPro: 2.124 ± 0.539
1.888GluGln: 1.888 ± 0.468
2.596GluArg: 2.596 ± 1.123
5.192GluSer: 5.192 ± 1.234
3.068GluThr: 3.068 ± 0.453
3.304GluVal: 3.304 ± 0.459
0.944GluTrp: 0.944 ± 0.352
1.652GluTyr: 1.652 ± 0.331
0.0GluXaa: 0.0 ± 0.0
Phe
0.944PheAla: 0.944 ± 0.285
0.472PheCys: 0.472 ± 0.4
2.36PheAsp: 2.36 ± 0.666
0.944PheGlu: 0.944 ± 0.388
0.708PhePhe: 0.708 ± 0.29
1.888PheGly: 1.888 ± 0.706
1.18PheHis: 1.18 ± 0.563
1.888PheIle: 1.888 ± 0.704
2.36PheLys: 2.36 ± 0.264
2.832PheLeu: 2.832 ± 0.723
1.416PheMet: 1.416 ± 0.754
1.416PheAsn: 1.416 ± 0.919
1.652PhePro: 1.652 ± 1.072
1.416PheGln: 1.416 ± 0.798
1.416PheArg: 1.416 ± 0.428
4.012PheSer: 4.012 ± 0.725
2.124PheThr: 2.124 ± 0.539
0.944PheVal: 0.944 ± 0.392
0.472PheTrp: 0.472 ± 0.209
0.708PheTyr: 0.708 ± 0.334
0.0PheXaa: 0.0 ± 0.0
Gly
2.36GlyAla: 2.36 ± 1.627
0.708GlyCys: 0.708 ± 0.455
6.372GlyAsp: 6.372 ± 1.084
1.416GlyGlu: 1.416 ± 0.429
2.124GlyPhe: 2.124 ± 0.795
6.608GlyGly: 6.608 ± 1.105
0.944GlyHis: 0.944 ± 0.357
2.596GlyIle: 2.596 ± 0.857
4.484GlyLys: 4.484 ± 0.932
5.664GlyLeu: 5.664 ± 1.538
1.888GlyMet: 1.888 ± 0.567
4.012GlyAsn: 4.012 ± 1.08
2.124GlyPro: 2.124 ± 1.207
2.596GlyGln: 2.596 ± 2.183
2.36GlyArg: 2.36 ± 0.469
5.428GlySer: 5.428 ± 1.056
4.012GlyThr: 4.012 ± 0.769
4.956GlyVal: 4.956 ± 0.799
0.944GlyTrp: 0.944 ± 0.434
1.888GlyTyr: 1.888 ± 0.676
0.0GlyXaa: 0.0 ± 0.0
His
0.708HisAla: 0.708 ± 0.459
0.0HisCys: 0.0 ± 0.0
1.888HisAsp: 1.888 ± 0.804
0.708HisGlu: 0.708 ± 0.459
0.944HisPhe: 0.944 ± 0.388
1.416HisGly: 1.416 ± 0.687
0.472HisHis: 0.472 ± 0.306
1.416HisIle: 1.416 ± 0.383
0.708HisLys: 0.708 ± 0.377
1.652HisLeu: 1.652 ± 0.77
0.708HisMet: 0.708 ± 0.319
0.708HisAsn: 0.708 ± 0.287
2.124HisPro: 2.124 ± 0.661
0.944HisGln: 0.944 ± 0.264
1.18HisArg: 1.18 ± 0.366
1.18HisSer: 1.18 ± 0.498
1.888HisThr: 1.888 ± 0.784
0.944HisVal: 0.944 ± 0.385
0.236HisTrp: 0.236 ± 0.303
0.944HisTyr: 0.944 ± 0.539
0.0HisXaa: 0.0 ± 0.0
Ile
1.888IleAla: 1.888 ± 0.444
1.888IleCys: 1.888 ± 0.432
3.776IleAsp: 3.776 ± 1.054
2.124IleGlu: 2.124 ± 0.447
1.416IlePhe: 1.416 ± 0.652
4.248IleGly: 4.248 ± 0.801
1.18IleHis: 1.18 ± 0.49
6.844IleIle: 6.844 ± 1.571
3.776IleLys: 3.776 ± 0.804
5.664IleLeu: 5.664 ± 1.412
3.54IleMet: 3.54 ± 0.937
5.428IleAsn: 5.428 ± 0.421
4.484IlePro: 4.484 ± 0.472
2.36IleGln: 2.36 ± 0.312
3.304IleArg: 3.304 ± 1.141
5.428IleSer: 5.428 ± 1.324
6.844IleThr: 6.844 ± 1.127
3.776IleVal: 3.776 ± 1.317
1.416IleTrp: 1.416 ± 0.91
3.776IleTyr: 3.776 ± 0.621
0.0IleXaa: 0.0 ± 0.0
Lys
4.248LysAla: 4.248 ± 1.155
0.944LysCys: 0.944 ± 0.444
2.832LysAsp: 2.832 ± 0.826
4.956LysGlu: 4.956 ± 0.998
2.832LysPhe: 2.832 ± 0.774
3.068LysGly: 3.068 ± 0.949
2.124LysHis: 2.124 ± 0.577
3.068LysIle: 3.068 ± 1.053
2.596LysLys: 2.596 ± 0.938
4.956LysLeu: 4.956 ± 0.824
2.36LysMet: 2.36 ± 0.372
2.124LysAsn: 2.124 ± 0.388
2.124LysPro: 2.124 ± 0.537
2.596LysGln: 2.596 ± 0.789
4.72LysArg: 4.72 ± 1.265
2.832LysSer: 2.832 ± 0.833
3.776LysThr: 3.776 ± 1.086
3.54LysVal: 3.54 ± 0.83
0.472LysTrp: 0.472 ± 0.209
1.652LysTyr: 1.652 ± 0.565
0.0LysXaa: 0.0 ± 0.0
Leu
5.192LeuAla: 5.192 ± 1.981
0.944LeuCys: 0.944 ± 0.338
4.72LeuAsp: 4.72 ± 0.804
3.304LeuGlu: 3.304 ± 0.377
2.832LeuPhe: 2.832 ± 1.085
6.608LeuGly: 6.608 ± 1.267
2.36LeuHis: 2.36 ± 0.297
7.08LeuIle: 7.08 ± 1.17
6.844LeuLys: 6.844 ± 1.477
5.664LeuLeu: 5.664 ± 1.246
2.832LeuMet: 2.832 ± 0.844
5.664LeuAsn: 5.664 ± 1.091
2.596LeuPro: 2.596 ± 0.514
2.596LeuGln: 2.596 ± 1.053
4.956LeuArg: 4.956 ± 1.737
7.553LeuSer: 7.553 ± 1.416
4.248LeuThr: 4.248 ± 0.739
6.136LeuVal: 6.136 ± 0.91
0.944LeuTrp: 0.944 ± 0.417
3.54LeuTyr: 3.54 ± 0.542
0.0LeuXaa: 0.0 ± 0.0
Met
3.304MetAla: 3.304 ± 0.407
0.472MetCys: 0.472 ± 0.209
1.888MetAsp: 1.888 ± 0.695
1.18MetGlu: 1.18 ± 0.377
0.708MetPhe: 0.708 ± 0.337
1.18MetGly: 1.18 ± 0.595
0.236MetHis: 0.236 ± 0.285
3.54MetIle: 3.54 ± 1.18
1.888MetLys: 1.888 ± 0.732
4.012MetLeu: 4.012 ± 1.022
0.944MetMet: 0.944 ± 0.631
0.944MetAsn: 0.944 ± 0.357
1.18MetPro: 1.18 ± 0.523
0.708MetGln: 0.708 ± 0.319
2.124MetArg: 2.124 ± 0.539
3.776MetSer: 3.776 ± 1.032
3.304MetThr: 3.304 ± 0.539
1.416MetVal: 1.416 ± 1.067
0.236MetTrp: 0.236 ± 0.303
2.36MetTyr: 2.36 ± 0.455
0.0MetXaa: 0.0 ± 0.0
Asn
4.012AsnAla: 4.012 ± 1.706
0.708AsnCys: 0.708 ± 0.377
1.652AsnAsp: 1.652 ± 0.345
2.124AsnGlu: 2.124 ± 0.47
1.416AsnPhe: 1.416 ± 0.641
2.36AsnGly: 2.36 ± 0.917
1.416AsnHis: 1.416 ± 0.783
4.248AsnIle: 4.248 ± 0.811
2.832AsnLys: 2.832 ± 0.803
4.956AsnLeu: 4.956 ± 1.328
2.124AsnMet: 2.124 ± 0.656
3.54AsnAsn: 3.54 ± 0.668
3.068AsnPro: 3.068 ± 1.624
2.36AsnGln: 2.36 ± 0.807
0.944AsnArg: 0.944 ± 0.323
2.832AsnSer: 2.832 ± 1.174
3.304AsnThr: 3.304 ± 0.882
4.012AsnVal: 4.012 ± 0.85
0.708AsnTrp: 0.708 ± 0.337
1.416AsnTyr: 1.416 ± 0.471
0.0AsnXaa: 0.0 ± 0.0
Pro
3.54ProAla: 3.54 ± 1.652
0.472ProCys: 0.472 ± 0.209
2.124ProAsp: 2.124 ± 0.63
2.832ProGlu: 2.832 ± 1.372
1.416ProPhe: 1.416 ± 0.499
3.304ProGly: 3.304 ± 0.886
0.708ProHis: 0.708 ± 0.405
4.484ProIle: 4.484 ± 1.477
2.596ProLys: 2.596 ± 0.442
3.54ProLeu: 3.54 ± 1.168
1.652ProMet: 1.652 ± 0.596
1.888ProAsn: 1.888 ± 1.015
5.192ProPro: 5.192 ± 3.736
1.652ProGln: 1.652 ± 0.395
2.36ProArg: 2.36 ± 0.542
3.068ProSer: 3.068 ± 0.893
1.888ProThr: 1.888 ± 0.391
1.18ProVal: 1.18 ± 0.779
0.236ProTrp: 0.236 ± 0.268
2.124ProTyr: 2.124 ± 0.27
0.0ProXaa: 0.0 ± 0.0
Gln
1.416GlnAla: 1.416 ± 0.641
0.236GlnCys: 0.236 ± 0.153
1.888GlnAsp: 1.888 ± 0.714
3.068GlnGlu: 3.068 ± 0.579
1.416GlnPhe: 1.416 ± 0.474
3.304GlnGly: 3.304 ± 1.138
0.708GlnHis: 0.708 ± 0.537
3.304GlnIle: 3.304 ± 0.331
2.36GlnLys: 2.36 ± 0.716
2.36GlnLeu: 2.36 ± 0.398
1.888GlnMet: 1.888 ± 0.941
1.888GlnAsn: 1.888 ± 0.418
1.416GlnPro: 1.416 ± 0.765
1.888GlnGln: 1.888 ± 1.409
2.596GlnArg: 2.596 ± 0.436
1.888GlnSer: 1.888 ± 0.428
1.652GlnThr: 1.652 ± 0.912
2.832GlnVal: 2.832 ± 1.033
0.236GlnTrp: 0.236 ± 0.303
0.944GlnTyr: 0.944 ± 0.751
0.0GlnXaa: 0.0 ± 0.0
Arg
2.124ArgAla: 2.124 ± 0.633
0.472ArgCys: 0.472 ± 0.306
3.068ArgAsp: 3.068 ± 0.47
3.068ArgGlu: 3.068 ± 1.054
2.124ArgPhe: 2.124 ± 0.489
3.776ArgGly: 3.776 ± 0.86
0.708ArgHis: 0.708 ± 0.29
3.776ArgIle: 3.776 ± 0.681
2.596ArgLys: 2.596 ± 0.603
4.012ArgLeu: 4.012 ± 0.792
2.596ArgMet: 2.596 ± 0.572
2.36ArgAsn: 2.36 ± 0.795
1.652ArgPro: 1.652 ± 0.703
1.888ArgGln: 1.888 ± 0.656
2.832ArgArg: 2.832 ± 0.766
3.54ArgSer: 3.54 ± 1.03
3.304ArgThr: 3.304 ± 0.911
4.248ArgVal: 4.248 ± 0.733
0.472ArgTrp: 0.472 ± 0.425
1.888ArgTyr: 1.888 ± 0.602
0.0ArgXaa: 0.0 ± 0.0
Ser
3.068SerAla: 3.068 ± 1.115
1.652SerCys: 1.652 ± 0.942
3.54SerAsp: 3.54 ± 1.828
4.012SerGlu: 4.012 ± 1.231
3.304SerPhe: 3.304 ± 0.912
4.012SerGly: 4.012 ± 0.896
1.888SerHis: 1.888 ± 0.528
3.776SerIle: 3.776 ± 1.187
4.956SerLys: 4.956 ± 1.09
7.789SerLeu: 7.789 ± 1.733
3.068SerMet: 3.068 ± 0.872
2.832SerAsn: 2.832 ± 0.584
3.304SerPro: 3.304 ± 0.674
3.068SerGln: 3.068 ± 1.222
4.72SerArg: 4.72 ± 0.939
6.372SerSer: 6.372 ± 1.984
4.484SerThr: 4.484 ± 1.015
4.72SerVal: 4.72 ± 0.693
1.888SerTrp: 1.888 ± 0.484
3.068SerTyr: 3.068 ± 1.128
0.0SerXaa: 0.0 ± 0.0
Thr
3.54ThrAla: 3.54 ± 1.259
0.944ThrCys: 0.944 ± 0.357
3.54ThrAsp: 3.54 ± 0.531
4.484ThrGlu: 4.484 ± 1.069
1.652ThrPhe: 1.652 ± 0.286
2.596ThrGly: 2.596 ± 0.792
1.416ThrHis: 1.416 ± 0.819
3.54ThrIle: 3.54 ± 0.532
3.776ThrLys: 3.776 ± 0.873
5.664ThrLeu: 5.664 ± 1.464
1.888ThrMet: 1.888 ± 0.555
2.36ThrAsn: 2.36 ± 0.87
4.012ThrPro: 4.012 ± 1.134
3.776ThrGln: 3.776 ± 1.015
3.068ThrArg: 3.068 ± 0.591
6.372ThrSer: 6.372 ± 1.183
7.08ThrThr: 7.08 ± 2.63
4.956ThrVal: 4.956 ± 0.67
1.18ThrTrp: 1.18 ± 0.514
3.304ThrTyr: 3.304 ± 0.728
0.0ThrXaa: 0.0 ± 0.0
Val
4.484ValAla: 4.484 ± 1.39
1.888ValCys: 1.888 ± 0.521
3.776ValAsp: 3.776 ± 0.668
5.664ValGlu: 5.664 ± 0.624
1.416ValPhe: 1.416 ± 0.547
3.068ValGly: 3.068 ± 0.338
0.236ValHis: 0.236 ± 0.153
5.192ValIle: 5.192 ± 1.405
3.068ValLys: 3.068 ± 0.47
5.664ValLeu: 5.664 ± 1.669
1.416ValMet: 1.416 ± 0.66
3.54ValAsn: 3.54 ± 1.115
1.416ValPro: 1.416 ± 0.532
2.124ValGln: 2.124 ± 1.0
2.596ValArg: 2.596 ± 0.677
4.484ValSer: 4.484 ± 1.46
4.72ValThr: 4.72 ± 1.13
1.888ValVal: 1.888 ± 0.808
0.472ValTrp: 0.472 ± 0.502
2.124ValTyr: 2.124 ± 0.75
0.0ValXaa: 0.0 ± 0.0
Trp
0.944TrpAla: 0.944 ± 0.508
0.472TrpCys: 0.472 ± 0.345
0.944TrpAsp: 0.944 ± 0.357
0.944TrpGlu: 0.944 ± 0.47
0.472TrpPhe: 0.472 ± 0.209
0.944TrpGly: 0.944 ± 0.613
0.472TrpHis: 0.472 ± 0.536
2.124TrpIle: 2.124 ± 1.12
1.652TrpLys: 1.652 ± 0.738
0.944TrpLeu: 0.944 ± 0.264
0.236TrpMet: 0.236 ± 0.153
0.708TrpAsn: 0.708 ± 0.29
0.236TrpPro: 0.236 ± 0.153
0.0TrpGln: 0.0 ± 0.0
0.944TrpArg: 0.944 ± 0.511
0.236TrpSer: 0.236 ± 0.153
1.18TrpThr: 1.18 ± 0.377
0.472TrpVal: 0.472 ± 0.446
0.708TrpTrp: 0.708 ± 0.249
0.708TrpTyr: 0.708 ± 0.337
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.652TyrAla: 1.652 ± 0.369
1.18TyrCys: 1.18 ± 1.012
1.652TyrAsp: 1.652 ± 1.058
2.832TyrGlu: 2.832 ± 0.592
2.36TyrPhe: 2.36 ± 0.829
1.652TyrGly: 1.652 ± 0.827
0.708TyrHis: 0.708 ± 0.334
2.832TyrIle: 2.832 ± 0.787
2.36TyrLys: 2.36 ± 0.492
4.484TyrLeu: 4.484 ± 0.734
1.652TyrMet: 1.652 ± 0.453
1.416TyrAsn: 1.416 ± 0.476
1.652TyrPro: 1.652 ± 0.704
1.652TyrGln: 1.652 ± 0.391
1.652TyrArg: 1.652 ± 0.577
2.832TyrSer: 2.832 ± 0.574
1.888TyrThr: 1.888 ± 0.678
1.888TyrVal: 1.888 ± 0.405
0.944TyrTrp: 0.944 ± 0.388
0.708TyrTyr: 0.708 ± 0.455
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4238 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski