Amino acid dipepetide frequency for Chimpanzee faeces associated microphage 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.327AlaAla: 5.327 ± 3.099
1.522AlaCys: 1.522 ± 1.429
3.805AlaAsp: 3.805 ± 1.259
3.044AlaGlu: 3.044 ± 2.174
6.088AlaPhe: 6.088 ± 1.891
3.805AlaGly: 3.805 ± 2.542
3.805AlaHis: 3.805 ± 1.911
3.044AlaIle: 3.044 ± 2.858
1.522AlaLys: 1.522 ± 0.893
6.849AlaLeu: 6.849 ± 2.494
1.522AlaMet: 1.522 ± 0.893
3.805AlaAsn: 3.805 ± 1.858
2.283AlaPro: 2.283 ± 0.914
5.327AlaGln: 5.327 ± 2.227
8.371AlaArg: 8.371 ± 2.362
10.654AlaSer: 10.654 ± 5.131
3.044AlaThr: 3.044 ± 1.345
5.327AlaVal: 5.327 ± 1.546
0.761AlaTrp: 0.761 ± 0.764
3.805AlaTyr: 3.805 ± 1.526
0.0AlaXaa: 0.0 ± 0.0
Cys
1.522CysAla: 1.522 ± 0.67
0.0CysCys: 0.0 ± 0.0
2.283CysAsp: 2.283 ± 1.302
0.761CysGlu: 0.761 ± 1.258
2.283CysPhe: 2.283 ± 2.291
0.761CysGly: 0.761 ± 0.764
0.761CysHis: 0.761 ± 0.764
0.0CysIle: 0.0 ± 0.0
0.761CysLys: 0.761 ± 0.517
3.044CysLeu: 3.044 ± 1.182
0.0CysMet: 0.0 ± 0.0
0.761CysAsn: 0.761 ± 1.258
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.522CysArg: 1.522 ± 0.67
0.761CysSer: 0.761 ± 0.517
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.761CysTyr: 0.761 ± 0.764
0.0CysXaa: 0.0 ± 0.0
Asp
4.566AspAla: 4.566 ± 1.105
1.522AspCys: 1.522 ± 1.429
3.805AspAsp: 3.805 ± 1.021
3.044AspGlu: 3.044 ± 2.067
6.088AspPhe: 6.088 ± 2.376
3.805AspGly: 3.805 ± 1.526
1.522AspHis: 1.522 ± 1.171
1.522AspIle: 1.522 ± 1.296
3.805AspLys: 3.805 ± 2.248
8.371AspLeu: 8.371 ± 2.362
1.522AspMet: 1.522 ± 0.623
2.283AspAsn: 2.283 ± 1.341
3.044AspPro: 3.044 ± 1.06
0.761AspGln: 0.761 ± 1.258
3.044AspArg: 3.044 ± 0.597
6.088AspSer: 6.088 ± 3.194
3.044AspThr: 3.044 ± 1.163
1.522AspVal: 1.522 ± 1.033
1.522AspTrp: 1.522 ± 0.67
4.566AspTyr: 4.566 ± 1.87
0.0AspXaa: 0.0 ± 0.0
Glu
3.805GluAla: 3.805 ± 2.887
0.0GluCys: 0.0 ± 0.0
1.522GluAsp: 1.522 ± 1.429
1.522GluGlu: 1.522 ± 1.429
2.283GluPhe: 2.283 ± 0.557
0.0GluGly: 0.0 ± 0.0
1.522GluHis: 1.522 ± 1.033
3.044GluIle: 3.044 ± 2.067
3.044GluLys: 3.044 ± 3.802
0.761GluLeu: 0.761 ± 0.517
0.761GluMet: 0.761 ± 0.607
1.522GluAsn: 1.522 ± 0.623
1.522GluPro: 1.522 ± 1.171
3.044GluGln: 3.044 ± 1.04
4.566GluArg: 4.566 ± 1.105
4.566GluSer: 4.566 ± 2.68
0.761GluThr: 0.761 ± 0.764
5.327GluVal: 5.327 ± 1.032
1.522GluTrp: 1.522 ± 1.38
3.044GluTyr: 3.044 ± 1.335
0.0GluXaa: 0.0 ± 0.0
Phe
3.044PheAla: 3.044 ± 0.597
1.522PheCys: 1.522 ± 0.623
3.044PheAsp: 3.044 ± 0.597
1.522PheGlu: 1.522 ± 0.893
4.566PhePhe: 4.566 ± 1.494
7.61PheGly: 7.61 ± 1.805
1.522PheHis: 1.522 ± 0.67
3.044PheIle: 3.044 ± 1.597
1.522PheLys: 1.522 ± 0.67
3.044PheLeu: 3.044 ± 1.182
0.761PheMet: 0.761 ± 0.517
3.044PheAsn: 3.044 ± 1.345
0.761PhePro: 0.761 ± 0.764
1.522PheGln: 1.522 ± 1.033
1.522PheArg: 1.522 ± 0.67
5.327PheSer: 5.327 ± 1.032
1.522PheThr: 1.522 ± 1.171
3.805PheVal: 3.805 ± 0.967
0.761PheTrp: 0.761 ± 1.258
1.522PheTyr: 1.522 ± 1.033
0.0PheXaa: 0.0 ± 0.0
Gly
4.566GlyAla: 4.566 ± 4.139
1.522GlyCys: 1.522 ± 1.527
3.805GlyAsp: 3.805 ± 1.796
4.566GlyGlu: 4.566 ± 1.494
2.283GlyPhe: 2.283 ± 1.371
6.849GlyGly: 6.849 ± 2.218
0.0GlyHis: 0.0 ± 0.0
2.283GlyIle: 2.283 ± 1.55
6.088GlyLys: 6.088 ± 1.502
5.327GlyLeu: 5.327 ± 1.923
0.0GlyMet: 0.0 ± 0.999
7.61GlyAsn: 7.61 ± 1.551
1.522GlyPro: 1.522 ± 1.527
1.522GlyGln: 1.522 ± 1.38
0.761GlyArg: 0.761 ± 0.517
6.088GlySer: 6.088 ± 1.929
3.044GlyThr: 3.044 ± 1.597
8.371GlyVal: 8.371 ± 1.515
1.522GlyTrp: 1.522 ± 0.67
2.283GlyTyr: 2.283 ± 0.914
0.0GlyXaa: 0.0 ± 0.0
His
1.522HisAla: 1.522 ± 1.527
0.0HisCys: 0.0 ± 0.0
3.044HisAsp: 3.044 ± 2.076
2.283HisGlu: 2.283 ± 2.291
1.522HisPhe: 1.522 ± 1.033
0.761HisGly: 0.761 ± 0.517
0.761HisHis: 0.761 ± 0.517
1.522HisIle: 1.522 ± 1.429
0.761HisLys: 0.761 ± 0.517
0.761HisLeu: 0.761 ± 0.517
0.761HisMet: 0.761 ± 0.473
0.0HisAsn: 0.0 ± 0.0
0.761HisPro: 0.761 ± 0.764
0.761HisGln: 0.761 ± 0.69
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.761HisVal: 0.761 ± 0.517
0.761HisTrp: 0.761 ± 0.517
0.761HisTyr: 0.761 ± 0.764
0.0HisXaa: 0.0 ± 0.0
Ile
2.283IleAla: 2.283 ± 1.651
0.761IleCys: 0.761 ± 0.517
0.761IleAsp: 0.761 ± 0.517
1.522IleGlu: 1.522 ± 0.623
0.0IlePhe: 0.0 ± 0.0
6.088IleGly: 6.088 ± 0.99
0.0IleHis: 0.0 ± 0.0
0.761IleIle: 0.761 ± 1.258
4.566IleLys: 4.566 ± 2.126
1.522IleLeu: 1.522 ± 1.171
0.0IleMet: 0.0 ± 0.0
1.522IleAsn: 1.522 ± 1.171
3.805IlePro: 3.805 ± 1.803
1.522IleGln: 1.522 ± 1.429
0.761IleArg: 0.761 ± 0.764
0.761IleSer: 0.761 ± 0.764
3.044IleThr: 3.044 ± 1.597
0.761IleVal: 0.761 ± 0.517
1.522IleTrp: 1.522 ± 1.033
0.761IleTyr: 0.761 ± 0.517
0.0IleXaa: 0.0 ± 0.0
Lys
9.893LysAla: 9.893 ± 4.434
1.522LysCys: 1.522 ± 0.67
4.566LysAsp: 4.566 ± 1.492
2.283LysGlu: 2.283 ± 1.55
2.283LysPhe: 2.283 ± 0.914
1.522LysGly: 1.522 ± 1.38
0.0LysHis: 0.0 ± 0.0
0.761LysIle: 0.761 ± 0.517
3.044LysLys: 3.044 ± 1.633
2.283LysLeu: 2.283 ± 0.914
0.761LysMet: 0.761 ± 0.587
2.283LysAsn: 2.283 ± 0.557
2.283LysPro: 2.283 ± 2.375
0.761LysGln: 0.761 ± 0.69
7.61LysArg: 7.61 ± 1.875
3.805LysSer: 3.805 ± 1.825
1.522LysThr: 1.522 ± 1.171
2.283LysVal: 2.283 ± 2.069
0.0LysTrp: 0.0 ± 0.0
0.761LysTyr: 0.761 ± 1.258
0.0LysXaa: 0.0 ± 0.0
Leu
7.61LeuAla: 7.61 ± 1.551
0.761LeuCys: 0.761 ± 0.517
3.044LeuAsp: 3.044 ± 1.182
4.566LeuGlu: 4.566 ± 2.002
3.805LeuPhe: 3.805 ± 1.942
6.088LeuGly: 6.088 ± 1.783
2.283LeuHis: 2.283 ± 2.291
3.044LeuIle: 3.044 ± 1.597
3.044LeuLys: 3.044 ± 1.867
3.805LeuLeu: 3.805 ± 1.396
1.522LeuMet: 1.522 ± 0.893
6.088LeuAsn: 6.088 ± 1.783
7.61LeuPro: 7.61 ± 2.339
2.283LeuGln: 2.283 ± 0.921
7.61LeuArg: 7.61 ± 2.069
5.327LeuSer: 5.327 ± 1.448
5.327LeuThr: 5.327 ± 1.666
5.327LeuVal: 5.327 ± 1.68
1.522LeuTrp: 1.522 ± 0.893
1.522LeuTyr: 1.522 ± 1.296
0.0LeuXaa: 0.0 ± 0.0
Met
2.283MetAla: 2.283 ± 2.069
0.761MetCys: 0.761 ± 0.764
1.522MetAsp: 1.522 ± 0.67
0.761MetGlu: 0.761 ± 0.69
0.0MetPhe: 0.0 ± 0.0
0.761MetGly: 0.761 ± 0.517
0.761MetHis: 0.761 ± 0.764
1.522MetIle: 1.522 ± 1.033
0.0MetLys: 0.0 ± 0.0
1.522MetLeu: 1.522 ± 1.296
0.0MetMet: 0.0 ± 0.0
0.761MetAsn: 0.761 ± 0.517
2.283MetPro: 2.283 ± 0.921
0.761MetGln: 0.761 ± 0.517
0.0MetArg: 0.0 ± 0.0
3.044MetSer: 3.044 ± 0.597
0.761MetThr: 0.761 ± 1.258
0.0MetVal: 0.0 ± 0.0
0.761MetTrp: 0.761 ± 0.517
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.327AsnAla: 5.327 ± 3.277
0.761AsnCys: 0.761 ± 0.764
3.805AsnAsp: 3.805 ± 1.803
0.0AsnGlu: 0.0 ± 0.0
3.805AsnPhe: 3.805 ± 2.583
6.849AsnGly: 6.849 ± 1.686
1.522AsnHis: 1.522 ± 1.033
0.761AsnIle: 0.761 ± 0.69
2.283AsnLys: 2.283 ± 1.302
6.088AsnLeu: 6.088 ± 2.526
0.761AsnMet: 0.761 ± 0.69
1.522AsnAsn: 1.522 ± 0.623
3.044AsnPro: 3.044 ± 0.597
0.761AsnGln: 0.761 ± 0.69
3.044AsnArg: 3.044 ± 1.345
3.044AsnSer: 3.044 ± 1.06
5.327AsnThr: 5.327 ± 1.584
2.283AsnVal: 2.283 ± 0.914
0.761AsnTrp: 0.761 ± 0.69
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.522ProAla: 1.522 ± 0.67
0.761ProCys: 0.761 ± 0.764
2.283ProAsp: 2.283 ± 0.557
2.283ProGlu: 2.283 ± 0.921
1.522ProPhe: 1.522 ± 0.67
1.522ProGly: 1.522 ± 0.623
0.761ProHis: 0.761 ± 0.764
2.283ProIle: 2.283 ± 0.557
0.761ProLys: 0.761 ± 0.517
4.566ProLeu: 4.566 ± 0.748
0.761ProMet: 0.761 ± 0.517
2.283ProAsn: 2.283 ± 1.402
6.088ProPro: 6.088 ± 3.427
3.805ProGln: 3.805 ± 1.985
1.522ProArg: 1.522 ± 0.67
8.371ProSer: 8.371 ± 4.136
4.566ProThr: 4.566 ± 1.673
6.849ProVal: 6.849 ± 3.363
0.761ProTrp: 0.761 ± 0.517
0.761ProTyr: 0.761 ± 0.517
0.0ProXaa: 0.0 ± 0.0
Gln
5.327GlnAla: 5.327 ± 2.227
0.761GlnCys: 0.761 ± 1.258
1.522GlnAsp: 1.522 ± 1.033
2.283GlnGlu: 2.283 ± 1.209
0.761GlnPhe: 0.761 ± 0.517
2.283GlnGly: 2.283 ± 0.914
0.0GlnHis: 0.0 ± 0.0
0.761GlnIle: 0.761 ± 0.517
2.283GlnLys: 2.283 ± 0.914
3.044GlnLeu: 3.044 ± 1.787
1.522GlnMet: 1.522 ± 0.67
1.522GlnAsn: 1.522 ± 1.033
1.522GlnPro: 1.522 ± 1.296
0.761GlnGln: 0.761 ± 0.517
3.044GlnArg: 3.044 ± 1.247
5.327GlnSer: 5.327 ± 2.317
0.761GlnThr: 0.761 ± 0.517
0.761GlnVal: 0.761 ± 0.517
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.566ArgAla: 4.566 ± 1.02
0.761ArgCys: 0.761 ± 0.764
3.805ArgAsp: 3.805 ± 2.241
3.044ArgGlu: 3.044 ± 2.021
0.0ArgPhe: 0.0 ± 0.0
3.044ArgGly: 3.044 ± 1.348
0.761ArgHis: 0.761 ± 0.517
3.044ArgIle: 3.044 ± 1.801
4.566ArgLys: 4.566 ± 2.68
9.132ArgLeu: 9.132 ± 2.637
1.522ArgMet: 1.522 ± 0.67
2.283ArgAsn: 2.283 ± 0.557
4.566ArgPro: 4.566 ± 1.105
0.761ArgGln: 0.761 ± 0.69
3.805ArgArg: 3.805 ± 1.396
5.327ArgSer: 5.327 ± 0.555
2.283ArgThr: 2.283 ± 0.921
1.522ArgVal: 1.522 ± 0.623
2.283ArgTrp: 2.283 ± 0.914
5.327ArgTyr: 5.327 ± 1.955
0.0ArgXaa: 0.0 ± 0.0
Ser
9.132SerAla: 9.132 ± 1.497
0.761SerCys: 0.761 ± 0.517
8.371SerAsp: 8.371 ± 1.932
3.044SerGlu: 3.044 ± 2.237
2.283SerPhe: 2.283 ± 0.921
5.327SerGly: 5.327 ± 1.448
0.0SerHis: 0.0 ± 0.0
2.283SerIle: 2.283 ± 0.914
1.522SerLys: 1.522 ± 0.623
8.371SerLeu: 8.371 ± 1.61
1.522SerMet: 1.522 ± 1.033
9.893SerAsn: 9.893 ± 3.23
3.044SerPro: 3.044 ± 0.955
3.044SerGln: 3.044 ± 1.06
5.327SerArg: 5.327 ± 1.683
12.938SerSer: 12.938 ± 3.151
4.566SerThr: 4.566 ± 0.763
11.416SerVal: 11.416 ± 1.772
1.522SerTrp: 1.522 ± 1.38
2.283SerTyr: 2.283 ± 1.512
0.0SerXaa: 0.0 ± 0.0
Thr
5.327ThrAla: 5.327 ± 0.555
0.761ThrCys: 0.761 ± 0.517
4.566ThrAsp: 4.566 ± 1.673
2.283ThrGlu: 2.283 ± 1.302
2.283ThrPhe: 2.283 ± 1.196
3.805ThrGly: 3.805 ± 1.16
0.0ThrHis: 0.0 ± 0.0
2.283ThrIle: 2.283 ± 1.302
3.044ThrLys: 3.044 ± 1.348
4.566ThrLeu: 4.566 ± 1.494
0.761ThrMet: 0.761 ± 0.517
0.0ThrAsn: 0.0 ± 0.0
3.044ThrPro: 3.044 ± 3.615
0.761ThrGln: 0.761 ± 0.517
2.283ThrArg: 2.283 ± 0.914
4.566ThrSer: 4.566 ± 1.432
5.327ThrThr: 5.327 ± 2.244
0.761ThrVal: 0.761 ± 0.764
2.283ThrTrp: 2.283 ± 1.371
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.522ValAla: 1.522 ± 1.38
0.761ValCys: 0.761 ± 0.517
5.327ValAsp: 5.327 ± 3.264
3.044ValGlu: 3.044 ± 1.163
6.088ValPhe: 6.088 ± 1.783
6.088ValGly: 6.088 ± 0.459
0.0ValHis: 0.0 ± 0.0
0.761ValIle: 0.761 ± 0.517
5.327ValLys: 5.327 ± 2.431
5.327ValLeu: 5.327 ± 2.075
0.761ValMet: 0.761 ± 0.517
1.522ValAsn: 1.522 ± 1.171
5.327ValPro: 5.327 ± 2.822
1.522ValGln: 1.522 ± 1.033
3.044ValArg: 3.044 ± 0.955
6.088ValSer: 6.088 ± 2.68
0.761ValThr: 0.761 ± 0.517
4.566ValVal: 4.566 ± 1.619
2.283ValTrp: 2.283 ± 0.914
3.044ValTyr: 3.044 ± 1.247
0.0ValXaa: 0.0 ± 0.0
Trp
2.283TrpAla: 2.283 ± 1.196
0.0TrpCys: 0.0 ± 0.0
1.522TrpAsp: 1.522 ± 0.623
1.522TrpGlu: 1.522 ± 0.623
0.761TrpPhe: 0.761 ± 0.764
0.761TrpGly: 0.761 ± 0.69
0.761TrpHis: 0.761 ± 0.517
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.283TrpLeu: 2.283 ± 0.557
0.761TrpMet: 0.761 ± 1.258
1.522TrpAsn: 1.522 ± 1.033
1.522TrpPro: 1.522 ± 0.67
1.522TrpGln: 1.522 ± 1.38
1.522TrpArg: 1.522 ± 1.38
1.522TrpSer: 1.522 ± 1.033
1.522TrpThr: 1.522 ± 0.67
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.283TrpTyr: 2.283 ± 0.557
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.283TyrAla: 2.283 ± 1.196
0.761TyrCys: 0.761 ± 0.764
3.044TyrAsp: 3.044 ± 1.06
0.761TyrGlu: 0.761 ± 0.764
2.283TyrPhe: 2.283 ± 0.914
3.044TyrGly: 3.044 ± 1.63
0.761TyrHis: 0.761 ± 0.764
0.0TyrIle: 0.0 ± 0.0
2.283TyrLys: 2.283 ± 1.302
1.522TyrLeu: 1.522 ± 0.623
1.522TyrMet: 1.522 ± 0.623
1.522TyrAsn: 1.522 ± 0.623
0.0TyrPro: 0.0 ± 0.0
3.044TyrGln: 3.044 ± 1.348
3.044TyrArg: 3.044 ± 1.335
3.044TyrSer: 3.044 ± 0.597
1.522TyrThr: 1.522 ± 0.623
1.522TyrVal: 1.522 ± 0.67
1.522TyrTrp: 1.522 ± 0.67
2.283TyrTyr: 2.283 ± 2.291
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1315 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski