Amino acid dipepetide frequency for Asanoa hainanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.298AlaAla: 23.298 ± 0.159	0.92AlaCys: 0.92 ± 0.021	8.828AlaAsp: 8.828 ± 0.061	7.741AlaGlu: 7.741 ± 0.07	3.74AlaPhe: 3.74 ± 0.034	13.957AlaGly: 13.957 ± 0.09	2.548AlaHis: 2.548 ± 0.034	4.737AlaIle: 4.737 ± 0.044	2.616AlaLys: 2.616 ± 0.041	14.641AlaLeu: 14.641 ± 0.104	2.565AlaMet: 2.565 ± 0.035	2.496AlaAsn: 2.496 ± 0.039	6.784AlaPro: 6.784 ± 0.075	3.486AlaGln: 3.486 ± 0.042	10.082AlaArg: 10.082 ± 0.077	6.127AlaSer: 6.127 ± 0.052	8.311AlaThr: 8.311 ± 0.066	12.826AlaVal: 12.826 ± 0.102	2.02AlaTrp: 2.02 ± 0.031	2.901AlaTyr: 2.901 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.918CysAla: 0.918 ± 0.02	0.088CysCys: 0.088 ± 0.006	0.449CysAsp: 0.449 ± 0.013	0.293CysGlu: 0.293 ± 0.01	0.209CysPhe: 0.209 ± 0.009	0.855CysGly: 0.855 ± 0.019	0.171CysHis: 0.171 ± 0.008	0.143CysIle: 0.143 ± 0.007	0.08CysLys: 0.08 ± 0.006	0.638CysLeu: 0.638 ± 0.014	0.095CysMet: 0.095 ± 0.006	0.124CysAsn: 0.124 ± 0.008	0.422CysPro: 0.422 ± 0.013	0.17CysGln: 0.17 ± 0.008	0.53CysArg: 0.53 ± 0.016	0.369CysSer: 0.369 ± 0.012	0.372CysThr: 0.372 ± 0.013	0.595CysVal: 0.595 ± 0.016	0.116CysTrp: 0.116 ± 0.007	0.162CysTyr: 0.162 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.806AspAla: 7.806 ± 0.063	0.354AspCys: 0.354 ± 0.012	4.168AspAsp: 4.168 ± 0.053	3.928AspGlu: 3.928 ± 0.046	1.582AspPhe: 1.582 ± 0.024	6.37AspGly: 6.37 ± 0.054	1.392AspHis: 1.392 ± 0.023	1.82AspIle: 1.82 ± 0.026	1.074AspLys: 1.074 ± 0.022	7.153AspLeu: 7.153 ± 0.06	0.702AspMet: 0.702 ± 0.02	1.155AspAsn: 1.155 ± 0.021	4.801AspPro: 4.801 ± 0.042	1.868AspGln: 1.868 ± 0.025	5.305AspArg: 5.305 ± 0.051	2.356AspSer: 2.356 ± 0.03	2.851AspThr: 2.851 ± 0.035	5.079AspVal: 5.079 ± 0.045	1.055AspTrp: 1.055 ± 0.021	1.271AspTyr: 1.271 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	6.313GluAla: 6.313 ± 0.066	0.291GluCys: 0.291 ± 0.01	2.091GluAsp: 2.091 ± 0.026	2.349GluGlu: 2.349 ± 0.036	1.503GluPhe: 1.503 ± 0.023	3.21GluGly: 3.21 ± 0.04	1.263GluHis: 1.263 ± 0.023	2.212GluIle: 2.212 ± 0.036	0.989GluLys: 0.989 ± 0.021	6.061GluLeu: 6.061 ± 0.059	0.805GluMet: 0.805 ± 0.019	0.821GluAsn: 0.821 ± 0.022	3.378GluPro: 3.378 ± 0.041	1.915GluGln: 1.915 ± 0.028	4.787GluArg: 4.787 ± 0.055	2.341GluSer: 2.341 ± 0.03	2.677GluThr: 2.677 ± 0.035	4.476GluVal: 4.476 ± 0.05	0.76GluTrp: 0.76 ± 0.018	0.933GluTyr: 0.933 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	4.166PheAla: 4.166 ± 0.043	0.255PheCys: 0.255 ± 0.01	2.155PheAsp: 2.155 ± 0.031	1.37PheGlu: 1.37 ± 0.024	0.96PhePhe: 0.96 ± 0.021	3.232PheGly: 3.232 ± 0.041	0.567PheHis: 0.567 ± 0.014	0.724PheIle: 0.724 ± 0.019	0.457PheLys: 0.457 ± 0.013	2.642PheLeu: 2.642 ± 0.033	0.388PheMet: 0.388 ± 0.015	0.626PheAsn: 0.626 ± 0.016	1.425PhePro: 1.425 ± 0.024	0.752PheGln: 0.752 ± 0.017	1.89PheArg: 1.89 ± 0.031	1.377PheSer: 1.377 ± 0.023	1.984PheThr: 1.984 ± 0.033	2.735PheVal: 2.735 ± 0.031	0.49PheTrp: 0.49 ± 0.013	0.645PheTyr: 0.645 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	11.057GlyAla: 11.057 ± 0.086	0.728GlyCys: 0.728 ± 0.017	5.462GlyAsp: 5.462 ± 0.053	4.268GlyGlu: 4.268 ± 0.045	3.046GlyPhe: 3.046 ± 0.038	8.823GlyGly: 8.823 ± 0.105	2.012GlyHis: 2.012 ± 0.027	3.534GlyIle: 3.534 ± 0.043	2.073GlyLys: 2.073 ± 0.033	9.461GlyLeu: 9.461 ± 0.07	1.823GlyMet: 1.823 ± 0.025	1.952GlyAsn: 1.952 ± 0.035	5.191GlyPro: 5.191 ± 0.066	2.726GlyGln: 2.726 ± 0.038	7.413GlyArg: 7.413 ± 0.063	5.202GlySer: 5.202 ± 0.064	5.753GlyThr: 5.753 ± 0.061	7.904GlyVal: 7.904 ± 0.064	1.908GlyTrp: 1.908 ± 0.03	2.434GlyTyr: 2.434 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	2.413HisAla: 2.413 ± 0.037	0.169HisCys: 0.169 ± 0.009	1.406HisAsp: 1.406 ± 0.023	1.112HisGlu: 1.112 ± 0.019	0.588HisPhe: 0.588 ± 0.014	2.075HisGly: 2.075 ± 0.034	0.62HisHis: 0.62 ± 0.015	0.576HisIle: 0.576 ± 0.016	0.302HisLys: 0.302 ± 0.011	2.323HisLeu: 2.323 ± 0.033	0.263HisMet: 0.263 ± 0.011	0.4HisAsn: 0.4 ± 0.012	1.58HisPro: 1.58 ± 0.025	0.601HisGln: 0.601 ± 0.015	1.885HisArg: 1.885 ± 0.031	0.863HisSer: 0.863 ± 0.018	1.073HisThr: 1.073 ± 0.022	1.657HisVal: 1.657 ± 0.027	0.33HisTrp: 0.33 ± 0.011	0.457HisTyr: 0.457 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	5.417IleAla: 5.417 ± 0.05	0.276IleCys: 0.276 ± 0.009	2.493IleAsp: 2.493 ± 0.031	2.033IleGlu: 2.033 ± 0.032	0.947IlePhe: 0.947 ± 0.021	3.79IleGly: 3.79 ± 0.043	0.605IleHis: 0.605 ± 0.014	0.998IleIle: 0.998 ± 0.023	0.706IleLys: 0.706 ± 0.018	2.629IleLeu: 2.629 ± 0.037	0.463IleMet: 0.463 ± 0.012	0.791IleAsn: 0.791 ± 0.018	1.777IlePro: 1.777 ± 0.028	0.768IleGln: 0.768 ± 0.018	2.431IleArg: 2.431 ± 0.03	1.858IleSer: 1.858 ± 0.026	2.192IleThr: 2.192 ± 0.034	3.219IleVal: 3.219 ± 0.039	0.473IleTrp: 0.473 ± 0.015	0.639IleTyr: 0.639 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	2.431LysAla: 2.431 ± 0.041	0.089LysCys: 0.089 ± 0.006	0.937LysAsp: 0.937 ± 0.023	0.824LysGlu: 0.824 ± 0.022	0.412LysPhe: 0.412 ± 0.011	1.349LysGly: 1.349 ± 0.027	0.393LysHis: 0.393 ± 0.012	0.851LysIle: 0.851 ± 0.02	0.536LysLys: 0.536 ± 0.016	1.895LysLeu: 1.895 ± 0.028	0.318LysMet: 0.318 ± 0.012	0.376LysAsn: 0.376 ± 0.014	1.245LysPro: 1.245 ± 0.026	0.587LysGln: 0.587 ± 0.016	1.369LysArg: 1.369 ± 0.028	0.957LysSer: 0.957 ± 0.023	1.188LysThr: 1.188 ± 0.023	1.709LysVal: 1.709 ± 0.029	0.256LysTrp: 0.256 ± 0.009	0.33LysTyr: 0.33 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	16.33LeuAla: 16.33 ± 0.113	0.706LeuCys: 0.706 ± 0.016	6.984LeuAsp: 6.984 ± 0.058	3.96LeuGlu: 3.96 ± 0.044	2.789LeuPhe: 2.789 ± 0.038	9.366LeuGly: 9.366 ± 0.073	2.102LeuHis: 2.102 ± 0.031	3.342LeuIle: 3.342 ± 0.04	1.494LeuLys: 1.494 ± 0.022	11.051LeuLeu: 11.051 ± 0.101	1.465LeuMet: 1.465 ± 0.024	1.663LeuAsn: 1.663 ± 0.027	6.294LeuPro: 6.294 ± 0.055	1.916LeuGln: 1.916 ± 0.03	8.944LeuArg: 8.944 ± 0.065	5.397LeuSer: 5.397 ± 0.041	6.708LeuThr: 6.708 ± 0.048	10.113LeuVal: 10.113 ± 0.081	1.306LeuTrp: 1.306 ± 0.029	1.699LeuTyr: 1.699 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.134MetAla: 2.134 ± 0.028	0.109MetCys: 0.109 ± 0.007	0.735MetAsp: 0.735 ± 0.018	0.589MetGlu: 0.589 ± 0.014	0.503MetPhe: 0.503 ± 0.015	1.136MetGly: 1.136 ± 0.023	0.332MetHis: 0.332 ± 0.012	0.719MetIle: 0.719 ± 0.019	0.341MetLys: 0.341 ± 0.013	1.714MetLeu: 1.714 ± 0.028	0.263MetMet: 0.263 ± 0.012	0.359MetAsn: 0.359 ± 0.012	1.063MetPro: 1.063 ± 0.02	0.387MetGln: 0.387 ± 0.012	1.52MetArg: 1.52 ± 0.022	1.18MetSer: 1.18 ± 0.021	1.539MetThr: 1.539 ± 0.025	1.349MetVal: 1.349 ± 0.023	0.225MetTrp: 0.225 ± 0.009	0.263MetTyr: 0.263 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.377AsnAla: 2.377 ± 0.035	0.17AsnCys: 0.17 ± 0.008	1.09AsnAsp: 1.09 ± 0.022	0.827AsnGlu: 0.827 ± 0.016	0.548AsnPhe: 0.548 ± 0.016	2.068AsnGly: 2.068 ± 0.043	0.397AsnHis: 0.397 ± 0.012	0.621AsnIle: 0.621 ± 0.017	0.368AsnLys: 0.368 ± 0.013	1.978AsnLeu: 1.978 ± 0.028	0.292AsnMet: 0.292 ± 0.011	0.56AsnAsn: 0.56 ± 0.023	1.586AsnPro: 1.586 ± 0.029	0.607AsnGln: 0.607 ± 0.017	1.405AsnArg: 1.405 ± 0.023	0.956AsnSer: 0.956 ± 0.023	1.164AsnThr: 1.164 ± 0.027	1.552AsnVal: 1.552 ± 0.031	0.341AsnTrp: 0.341 ± 0.012	0.482AsnTyr: 0.482 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	9.2ProAla: 9.2 ± 0.085	0.267ProCys: 0.267 ± 0.012	4.6ProAsp: 4.6 ± 0.043	3.48ProGlu: 3.48 ± 0.04	1.601ProPhe: 1.601 ± 0.024	6.238ProGly: 6.238 ± 0.069	1.192ProHis: 1.192 ± 0.023	1.822ProIle: 1.822 ± 0.029	1.051ProLys: 1.051 ± 0.02	5.095ProLeu: 5.095 ± 0.048	1.05ProMet: 1.05 ± 0.019	1.15ProAsn: 1.15 ± 0.025	4.084ProPro: 4.084 ± 0.074	1.431ProGln: 1.431 ± 0.026	3.861ProArg: 3.861 ± 0.044	3.262ProSer: 3.262 ± 0.046	3.977ProThr: 3.977 ± 0.055	5.375ProVal: 5.375 ± 0.05	0.979ProTrp: 0.979 ± 0.02	1.215ProTyr: 1.215 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.483GlnAla: 3.483 ± 0.038	0.146GlnCys: 0.146 ± 0.007	1.153GlnAsp: 1.153 ± 0.021	1.133GlnGlu: 1.133 ± 0.02	0.745GlnPhe: 0.745 ± 0.019	1.887GlnGly: 1.887 ± 0.03	0.598GlnHis: 0.598 ± 0.016	1.134GlnIle: 1.134 ± 0.021	0.479GlnLys: 0.479 ± 0.013	3.003GlnLeu: 3.003 ± 0.036	0.417GlnMet: 0.417 ± 0.011	0.51GlnAsn: 0.51 ± 0.015	1.858GlnPro: 1.858 ± 0.032	1.084GlnGln: 1.084 ± 0.026	2.589GlnArg: 2.589 ± 0.034	1.235GlnSer: 1.235 ± 0.023	1.394GlnThr: 1.394 ± 0.022	2.588GlnVal: 2.588 ± 0.03	0.506GlnTrp: 0.506 ± 0.014	0.483GlnTyr: 0.483 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	10.155ArgAla: 10.155 ± 0.078	0.512ArgCys: 0.512 ± 0.015	4.688ArgAsp: 4.688 ± 0.044	3.989ArgGlu: 3.989 ± 0.044	2.514ArgPhe: 2.514 ± 0.035	5.74ArgGly: 5.74 ± 0.055	1.945ArgHis: 1.945 ± 0.031	3.126ArgIle: 3.126 ± 0.036	1.389ArgLys: 1.389 ± 0.026	8.805ArgLeu: 8.805 ± 0.079	1.734ArgMet: 1.734 ± 0.027	1.391ArgAsn: 1.391 ± 0.025	4.957ArgPro: 4.957 ± 0.055	2.405ArgGln: 2.405 ± 0.032	7.932ArgArg: 7.932 ± 0.078	4.16ArgSer: 4.16 ± 0.046	4.747ArgThr: 4.747 ± 0.047	6.279ArgVal: 6.279 ± 0.058	1.58ArgTrp: 1.58 ± 0.024	1.868ArgTyr: 1.868 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.876SerAla: 6.876 ± 0.062	0.357SerCys: 0.357 ± 0.012	2.732SerAsp: 2.732 ± 0.032	2.02SerGlu: 2.02 ± 0.026	1.559SerPhe: 1.559 ± 0.027	5.705SerGly: 5.705 ± 0.06	0.895SerHis: 0.895 ± 0.02	1.713SerIle: 1.713 ± 0.027	0.841SerLys: 0.841 ± 0.018	4.638SerLeu: 4.638 ± 0.04	1.079SerMet: 1.079 ± 0.02	0.975SerAsn: 0.975 ± 0.025	3.211SerPro: 3.211 ± 0.038	1.204SerGln: 1.204 ± 0.024	3.693SerArg: 3.693 ± 0.042	2.761SerSer: 2.761 ± 0.038	3.356SerThr: 3.356 ± 0.039	4.379SerVal: 4.379 ± 0.047	1.001SerTrp: 1.001 ± 0.02	1.28SerTyr: 1.28 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	8.676ThrAla: 8.676 ± 0.071	0.406ThrCys: 0.406 ± 0.014	3.722ThrAsp: 3.722 ± 0.041	2.857ThrGlu: 2.857 ± 0.04	1.819ThrPhe: 1.819 ± 0.032	6.171ThrGly: 6.171 ± 0.064	1.1ThrHis: 1.1 ± 0.022	2.321ThrIle: 2.321 ± 0.037	1.085ThrLys: 1.085 ± 0.024	5.888ThrLeu: 5.888 ± 0.048	1.027ThrMet: 1.027 ± 0.02	1.303ThrAsn: 1.303 ± 0.029	3.954ThrPro: 3.954 ± 0.043	1.361ThrGln: 1.361 ± 0.025	3.984ThrArg: 3.984 ± 0.038	3.189ThrSer: 3.189 ± 0.035	4.115ThrThr: 4.115 ± 0.057	6.358ThrVal: 6.358 ± 0.06	1.024ThrTrp: 1.024 ± 0.02	1.322ThrTyr: 1.322 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	12.967ValAla: 12.967 ± 0.088	0.645ValCys: 0.645 ± 0.016	6.157ValAsp: 6.157 ± 0.055	4.656ValGlu: 4.656 ± 0.048	2.536ValPhe: 2.536 ± 0.032	7.628ValGly: 7.628 ± 0.068	1.714ValHis: 1.714 ± 0.03	3.053ValIle: 3.053 ± 0.036	1.558ValLys: 1.558 ± 0.026	9.734ValLeu: 9.734 ± 0.081	1.231ValMet: 1.231 ± 0.023	1.859ValAsn: 1.859 ± 0.03	5.195ValPro: 5.195 ± 0.048	1.831ValGln: 1.831 ± 0.027	6.962ValArg: 6.962 ± 0.053	4.643ValSer: 4.643 ± 0.048	5.964ValThr: 5.964 ± 0.06	9.311ValVal: 9.311 ± 0.078	1.171ValTrp: 1.171 ± 0.025	1.684ValTyr: 1.684 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	1.726TrpAla: 1.726 ± 0.028	0.144TrpCys: 0.144 ± 0.007	0.819TrpAsp: 0.819 ± 0.019	0.645TrpGlu: 0.645 ± 0.017	0.581TrpPhe: 0.581 ± 0.015	1.06TrpGly: 1.06 ± 0.023	0.438TrpHis: 0.438 ± 0.013	0.582TrpIle: 0.582 ± 0.017	0.293TrpLys: 0.293 ± 0.01	1.983TrpLeu: 1.983 ± 0.03	0.289TrpMet: 0.289 ± 0.011	0.422TrpAsn: 0.422 ± 0.014	0.941TrpPro: 0.941 ± 0.017	0.667TrpGln: 0.667 ± 0.016	1.536TrpArg: 1.536 ± 0.026	1.107TrpSer: 1.107 ± 0.026	1.109TrpThr: 1.109 ± 0.022	1.183TrpVal: 1.183 ± 0.023	0.418TrpTrp: 0.418 ± 0.013	0.376TrpTyr: 0.376 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.878TyrAla: 2.878 ± 0.035	0.167TyrCys: 0.167 ± 0.008	1.421TyrAsp: 1.421 ± 0.029	1.103TyrGlu: 1.103 ± 0.02	0.659TyrPhe: 0.659 ± 0.018	2.112TyrGly: 2.112 ± 0.028	0.411TyrHis: 0.411 ± 0.011	0.478TyrIle: 0.478 ± 0.014	0.32TyrLys: 0.32 ± 0.014	2.297TyrLeu: 2.297 ± 0.029	0.193TyrMet: 0.193 ± 0.007	0.455TyrAsn: 0.455 ± 0.017	1.183TyrPro: 1.183 ± 0.025	0.658TyrGln: 0.658 ± 0.017	1.8TyrArg: 1.8 ± 0.026	0.934TyrSer: 0.934 ± 0.022	1.207TyrThr: 1.207 ± 0.026	1.812TyrVal: 1.812 ± 0.026	0.356TyrTrp: 0.356 ± 0.01	0.48TyrTyr: 0.48 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8104 proteins (2630270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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