Amino acid dipepetide frequency for Strawberry vein banding virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.304AlaAla: 1.304 ± 0.739
0.0AlaCys: 0.0 ± 0.0
3.042AlaAsp: 3.042 ± 1.396
2.173AlaGlu: 2.173 ± 0.918
3.042AlaPhe: 3.042 ± 1.019
0.869AlaGly: 0.869 ± 0.658
2.173AlaHis: 2.173 ± 1.317
3.042AlaIle: 3.042 ± 0.881
3.911AlaLys: 3.911 ± 1.585
6.084AlaLeu: 6.084 ± 1.427
0.0AlaMet: 0.0 ± 0.0
2.173AlaAsn: 2.173 ± 0.818
3.477AlaPro: 3.477 ± 1.754
3.042AlaGln: 3.042 ± 1.023
3.477AlaArg: 3.477 ± 0.83
3.477AlaSer: 3.477 ± 0.641
0.869AlaThr: 0.869 ± 0.409
3.042AlaVal: 3.042 ± 0.781
0.0AlaTrp: 0.0 ± 0.0
2.608AlaTyr: 2.608 ± 1.513
0.0AlaXaa: 0.0 ± 0.0
Cys
0.869CysAla: 0.869 ± 0.396
0.435CysCys: 0.435 ± 0.406
1.304CysAsp: 1.304 ± 0.52
0.869CysGlu: 0.869 ± 0.8
0.0CysPhe: 0.0 ± 0.0
0.869CysGly: 0.869 ± 0.555
0.0CysHis: 0.0 ± 0.0
0.869CysIle: 0.869 ± 0.81
3.042CysLys: 3.042 ± 1.161
0.869CysLeu: 0.869 ± 0.555
0.435CysMet: 0.435 ± 0.418
1.304CysAsn: 1.304 ± 0.886
1.304CysPro: 1.304 ± 0.732
0.435CysGln: 0.435 ± 0.406
1.738CysArg: 1.738 ± 0.792
1.738CysSer: 1.738 ± 0.607
0.869CysThr: 0.869 ± 0.409
0.435CysVal: 0.435 ± 0.405
0.435CysTrp: 0.435 ± 0.406
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.173AspAla: 2.173 ± 0.906
2.173AspCys: 2.173 ± 1.134
4.346AspAsp: 4.346 ± 0.818
4.781AspGlu: 4.781 ± 1.444
1.304AspPhe: 1.304 ± 0.445
1.304AspGly: 1.304 ± 0.626
2.608AspHis: 2.608 ± 0.587
3.477AspIle: 3.477 ± 0.9
2.173AspLys: 2.173 ± 0.981
6.953AspLeu: 6.953 ± 1.577
0.435AspMet: 0.435 ± 0.329
4.346AspAsn: 4.346 ± 1.342
0.869AspPro: 0.869 ± 0.504
2.608AspGln: 2.608 ± 0.558
2.608AspArg: 2.608 ± 1.259
4.781AspSer: 4.781 ± 0.658
1.738AspThr: 1.738 ± 0.912
0.435AspVal: 0.435 ± 0.405
0.0AspTrp: 0.0 ± 0.0
1.738AspTyr: 1.738 ± 0.607
0.0AspXaa: 0.0 ± 0.0
Glu
3.477GluAla: 3.477 ± 1.702
0.435GluCys: 0.435 ± 0.329
5.215GluAsp: 5.215 ± 1.286
15.211GluGlu: 15.211 ± 3.726
2.173GluPhe: 2.173 ± 0.317
3.477GluGly: 3.477 ± 1.026
1.738GluHis: 1.738 ± 0.912
7.388GluIle: 7.388 ± 1.896
9.126GluLys: 9.126 ± 1.695
6.953GluLeu: 6.953 ± 0.901
2.608GluMet: 2.608 ± 1.454
2.608GluAsn: 2.608 ± 0.751
3.477GluPro: 3.477 ± 0.943
3.911GluGln: 3.911 ± 1.069
4.781GluArg: 4.781 ± 1.281
6.519GluSer: 6.519 ± 1.486
4.346GluThr: 4.346 ± 1.435
3.477GluVal: 3.477 ± 0.701
1.738GluTrp: 1.738 ± 0.607
4.346GluTyr: 4.346 ± 1.09
0.0GluXaa: 0.0 ± 0.0
Phe
0.869PheAla: 0.869 ± 0.46
1.738PheCys: 1.738 ± 0.792
2.608PheAsp: 2.608 ± 0.916
1.738PheGlu: 1.738 ± 0.723
1.738PhePhe: 1.738 ± 0.803
0.869PheGly: 0.869 ± 0.437
1.304PheHis: 1.304 ± 0.626
1.738PheIle: 1.738 ± 0.7
3.477PheLys: 3.477 ± 1.216
3.042PheLeu: 3.042 ± 0.896
0.435PheMet: 0.435 ± 0.329
0.869PheAsn: 0.869 ± 0.437
1.304PhePro: 1.304 ± 0.626
1.304PheGln: 1.304 ± 0.476
2.173PheArg: 2.173 ± 0.866
3.911PheSer: 3.911 ± 1.045
1.304PheThr: 1.304 ± 0.815
1.738PheVal: 1.738 ± 0.792
1.304PheTrp: 1.304 ± 0.604
1.304PheTyr: 1.304 ± 0.604
0.0PheXaa: 0.0 ± 0.0
Gly
1.304GlyAla: 1.304 ± 0.626
0.869GlyCys: 0.869 ± 0.629
1.304GlyAsp: 1.304 ± 0.987
3.042GlyGlu: 3.042 ± 0.362
1.304GlyPhe: 1.304 ± 0.626
1.738GlyGly: 1.738 ± 0.878
1.738GlyHis: 1.738 ± 0.57
3.477GlyIle: 3.477 ± 1.266
4.781GlyLys: 4.781 ± 0.931
4.781GlyLeu: 4.781 ± 0.931
0.435GlyMet: 0.435 ± 0.406
3.911GlyAsn: 3.911 ± 1.212
0.869GlyPro: 0.869 ± 0.557
1.304GlyGln: 1.304 ± 0.739
1.738GlyArg: 1.738 ± 0.419
3.042GlySer: 3.042 ± 1.0
2.608GlyThr: 2.608 ± 0.591
0.435GlyVal: 0.435 ± 0.405
0.435GlyTrp: 0.435 ± 0.329
1.738GlyTyr: 1.738 ± 0.57
0.0GlyXaa: 0.0 ± 0.0
His
0.435HisAla: 0.435 ± 0.329
0.435HisCys: 0.435 ± 0.4
1.304HisAsp: 1.304 ± 0.823
0.869HisGlu: 0.869 ± 0.536
1.738HisPhe: 1.738 ± 0.631
0.435HisGly: 0.435 ± 0.329
0.869HisHis: 0.869 ± 0.504
1.304HisIle: 1.304 ± 0.583
2.173HisLys: 2.173 ± 0.625
2.173HisLeu: 2.173 ± 0.845
0.869HisMet: 0.869 ± 0.487
1.304HisAsn: 1.304 ± 0.771
1.738HisPro: 1.738 ± 0.575
2.173HisGln: 2.173 ± 1.563
0.0HisArg: 0.0 ± 0.0
2.173HisSer: 2.173 ± 0.729
1.738HisThr: 1.738 ± 0.272
1.304HisVal: 1.304 ± 0.987
0.869HisTrp: 0.869 ± 0.409
0.435HisTyr: 0.435 ± 0.329
0.0HisXaa: 0.0 ± 0.0
Ile
2.608IleAla: 2.608 ± 1.57
3.042IleCys: 3.042 ± 0.948
3.042IleAsp: 3.042 ± 1.818
8.257IleGlu: 8.257 ± 1.59
2.608IlePhe: 2.608 ± 0.565
2.608IleGly: 2.608 ± 0.936
1.304IleHis: 1.304 ± 0.65
5.215IleIle: 5.215 ± 1.506
6.519IleLys: 6.519 ± 0.795
3.477IleLeu: 3.477 ± 0.922
1.738IleMet: 1.738 ± 0.703
3.042IleAsn: 3.042 ± 1.282
3.911IlePro: 3.911 ± 0.838
1.304IleGln: 1.304 ± 0.52
4.346IleArg: 4.346 ± 0.915
6.519IleSer: 6.519 ± 1.544
5.215IleThr: 5.215 ± 1.862
2.173IleVal: 2.173 ± 0.827
0.0IleTrp: 0.0 ± 0.0
3.911IleTyr: 3.911 ± 1.946
0.0IleXaa: 0.0 ± 0.0
Lys
7.823LysAla: 7.823 ± 1.219
1.304LysCys: 1.304 ± 0.547
4.346LysAsp: 4.346 ± 0.757
8.257LysGlu: 8.257 ± 1.338
3.042LysPhe: 3.042 ± 0.803
3.477LysGly: 3.477 ± 1.397
1.304LysHis: 1.304 ± 0.476
10.865LysIle: 10.865 ± 2.19
12.169LysLys: 12.169 ± 1.808
8.257LysLeu: 8.257 ± 0.918
0.435LysMet: 0.435 ± 0.443
3.477LysAsn: 3.477 ± 0.951
3.911LysPro: 3.911 ± 0.274
4.346LysGln: 4.346 ± 1.572
3.477LysArg: 3.477 ± 0.889
4.781LysSer: 4.781 ± 0.967
9.126LysThr: 9.126 ± 0.551
3.042LysVal: 3.042 ± 1.019
0.435LysTrp: 0.435 ± 0.443
2.173LysTyr: 2.173 ± 1.512
0.0LysXaa: 0.0 ± 0.0
Leu
5.65LeuAla: 5.65 ± 1.156
1.304LeuCys: 1.304 ± 0.321
6.519LeuAsp: 6.519 ± 1.544
9.126LeuGlu: 9.126 ± 1.473
2.173LeuPhe: 2.173 ± 0.546
6.519LeuGly: 6.519 ± 1.485
1.304LeuHis: 1.304 ± 0.321
4.781LeuIle: 4.781 ± 2.293
7.823LeuLys: 7.823 ± 1.819
9.126LeuLeu: 9.126 ± 1.299
1.304LeuMet: 1.304 ± 0.759
3.911LeuAsn: 3.911 ± 1.341
3.911LeuPro: 3.911 ± 1.37
4.781LeuGln: 4.781 ± 1.32
4.346LeuArg: 4.346 ± 1.3
7.823LeuSer: 7.823 ± 2.394
6.084LeuThr: 6.084 ± 2.222
5.215LeuVal: 5.215 ± 1.547
0.435LeuTrp: 0.435 ± 0.405
3.042LeuTyr: 3.042 ± 1.136
0.0LeuXaa: 0.0 ± 0.0
Met
0.435MetAla: 0.435 ± 0.329
0.869MetCys: 0.869 ± 0.396
1.304MetAsp: 1.304 ± 0.445
2.173MetGlu: 2.173 ± 0.632
0.435MetPhe: 0.435 ± 0.4
0.435MetGly: 0.435 ± 0.443
0.435MetHis: 0.435 ± 0.405
1.738MetIle: 1.738 ± 0.753
0.435MetLys: 0.435 ± 0.405
1.304MetLeu: 1.304 ± 0.601
0.435MetMet: 0.435 ± 0.541
1.304MetAsn: 1.304 ± 0.944
0.435MetPro: 0.435 ± 0.329
0.869MetGln: 0.869 ± 0.658
0.435MetArg: 0.435 ± 0.406
1.304MetSer: 1.304 ± 0.956
0.869MetThr: 0.869 ± 0.658
1.304MetVal: 1.304 ± 0.604
0.0MetTrp: 0.0 ± 0.0
0.435MetTyr: 0.435 ± 0.329
0.0MetXaa: 0.0 ± 0.0
Asn
2.173AsnAla: 2.173 ± 0.818
0.435AsnCys: 0.435 ± 0.4
1.738AsnAsp: 1.738 ± 0.459
2.608AsnGlu: 2.608 ± 0.916
1.304AsnPhe: 1.304 ± 0.987
0.869AsnGly: 0.869 ± 0.504
2.173AsnHis: 2.173 ± 0.317
3.477AsnIle: 3.477 ± 0.781
5.215AsnLys: 5.215 ± 1.173
5.215AsnLeu: 5.215 ± 0.863
1.304AsnMet: 1.304 ± 0.321
1.738AsnAsn: 1.738 ± 0.602
3.477AsnPro: 3.477 ± 1.438
1.738AsnGln: 1.738 ± 1.116
2.608AsnArg: 2.608 ± 1.483
3.477AsnSer: 3.477 ± 1.058
3.477AsnThr: 3.477 ± 1.976
1.738AsnVal: 1.738 ± 0.936
0.435AsnTrp: 0.435 ± 0.443
5.215AsnTyr: 5.215 ± 1.196
0.0AsnXaa: 0.0 ± 0.0
Pro
1.304ProAla: 1.304 ± 0.987
0.0ProCys: 0.0 ± 0.0
1.304ProAsp: 1.304 ± 0.626
7.388ProGlu: 7.388 ± 1.276
1.738ProPhe: 1.738 ± 0.57
1.304ProGly: 1.304 ± 0.476
1.304ProHis: 1.304 ± 0.476
5.215ProIle: 5.215 ± 1.248
4.781ProLys: 4.781 ± 1.274
3.477ProLeu: 3.477 ± 1.097
0.435ProMet: 0.435 ± 0.329
3.911ProAsn: 3.911 ± 0.962
0.0ProPro: 0.0 ± 0.0
4.346ProGln: 4.346 ± 0.346
1.304ProArg: 1.304 ± 0.815
1.738ProSer: 1.738 ± 0.747
1.304ProThr: 1.304 ± 0.445
0.869ProVal: 0.869 ± 0.396
0.435ProTrp: 0.435 ± 0.4
1.304ProTyr: 1.304 ± 0.425
0.0ProXaa: 0.0 ± 0.0
Gln
3.477GlnAla: 3.477 ± 0.599
0.435GlnCys: 0.435 ± 0.4
3.042GlnAsp: 3.042 ± 1.205
2.608GlnGlu: 2.608 ± 1.429
0.869GlnPhe: 0.869 ± 0.409
2.173GlnGly: 2.173 ± 0.546
0.435GlnHis: 0.435 ± 0.4
1.738GlnIle: 1.738 ± 0.888
3.042GlnLys: 3.042 ± 0.966
6.953GlnLeu: 6.953 ± 1.326
0.869GlnMet: 0.869 ± 0.409
1.738GlnAsn: 1.738 ± 0.849
2.173GlnPro: 2.173 ± 1.085
3.042GlnGln: 3.042 ± 1.338
1.304GlnArg: 1.304 ± 0.987
4.346GlnSer: 4.346 ± 0.99
1.738GlnThr: 1.738 ± 1.599
2.608GlnVal: 2.608 ± 0.774
0.435GlnTrp: 0.435 ± 0.4
2.608GlnTyr: 2.608 ± 1.14
0.0GlnXaa: 0.0 ± 0.0
Arg
2.173ArgAla: 2.173 ± 0.827
1.304ArgCys: 1.304 ± 0.321
1.304ArgAsp: 1.304 ± 0.734
4.346ArgGlu: 4.346 ± 0.348
1.738ArgPhe: 1.738 ± 0.67
3.042ArgGly: 3.042 ± 1.2
1.304ArgHis: 1.304 ± 0.425
2.608ArgIle: 2.608 ± 0.988
6.953ArgLys: 6.953 ± 2.428
3.911ArgLeu: 3.911 ± 1.379
3.042ArgMet: 3.042 ± 1.875
3.477ArgAsn: 3.477 ± 1.525
4.346ArgPro: 4.346 ± 1.773
1.304ArgGln: 1.304 ± 0.76
4.346ArgArg: 4.346 ± 2.39
0.869ArgSer: 0.869 ± 0.437
2.608ArgThr: 2.608 ± 0.825
1.304ArgVal: 1.304 ± 0.815
0.869ArgTrp: 0.869 ± 0.396
1.304ArgTyr: 1.304 ± 0.321
0.0ArgXaa: 0.0 ± 0.0
Ser
3.911SerAla: 3.911 ± 1.621
0.869SerCys: 0.869 ± 0.437
2.608SerAsp: 2.608 ± 0.598
6.953SerGlu: 6.953 ± 1.517
2.608SerPhe: 2.608 ± 1.094
3.042SerGly: 3.042 ± 0.727
1.304SerHis: 1.304 ± 0.445
3.042SerIle: 3.042 ± 0.939
5.65SerLys: 5.65 ± 0.981
8.692SerLeu: 8.692 ± 2.072
0.435SerMet: 0.435 ± 0.329
4.781SerAsn: 4.781 ± 1.364
3.911SerPro: 3.911 ± 1.337
2.608SerGln: 2.608 ± 1.028
5.215SerArg: 5.215 ± 1.248
8.257SerSer: 8.257 ± 2.417
6.084SerThr: 6.084 ± 1.513
2.173SerVal: 2.173 ± 1.245
0.869SerTrp: 0.869 ± 0.409
2.173SerTyr: 2.173 ± 1.294
0.0SerXaa: 0.0 ± 0.0
Thr
2.173ThrAla: 2.173 ± 1.126
0.869ThrCys: 0.869 ± 0.57
1.738ThrAsp: 1.738 ± 0.602
6.519ThrGlu: 6.519 ± 0.825
3.042ThrPhe: 3.042 ± 1.432
3.042ThrGly: 3.042 ± 0.646
0.869ThrHis: 0.869 ± 0.8
3.042ThrIle: 3.042 ± 1.164
5.65ThrLys: 5.65 ± 1.284
6.953ThrLeu: 6.953 ± 1.423
0.435ThrMet: 0.435 ± 0.316
4.346ThrAsn: 4.346 ± 2.209
2.608ThrPro: 2.608 ± 1.234
3.042ThrGln: 3.042 ± 0.81
2.608ThrArg: 2.608 ± 1.002
3.911ThrSer: 3.911 ± 1.195
3.477ThrThr: 3.477 ± 0.822
2.173ThrVal: 2.173 ± 0.519
0.435ThrTrp: 0.435 ± 0.329
2.173ThrTyr: 2.173 ± 0.933
0.0ThrXaa: 0.0 ± 0.0
Val
3.477ValAla: 3.477 ± 0.83
0.869ValCys: 0.869 ± 0.555
1.738ValAsp: 1.738 ± 0.912
2.173ValGlu: 2.173 ± 1.08
2.173ValPhe: 2.173 ± 0.611
3.042ValGly: 3.042 ± 0.986
0.435ValHis: 0.435 ± 0.4
3.042ValIle: 3.042 ± 1.125
3.911ValLys: 3.911 ± 0.491
3.042ValLeu: 3.042 ± 0.578
0.435ValMet: 0.435 ± 0.329
0.869ValAsn: 0.869 ± 0.396
0.0ValPro: 0.0 ± 0.0
2.173ValGln: 2.173 ± 0.731
3.042ValArg: 3.042 ± 1.858
2.608ValSer: 2.608 ± 0.89
2.173ValThr: 2.173 ± 0.826
1.304ValVal: 1.304 ± 0.848
0.0ValTrp: 0.0 ± 0.0
0.869ValTyr: 0.869 ± 0.409
0.0ValXaa: 0.0 ± 0.0
Trp
0.435TrpAla: 0.435 ± 0.4
0.435TrpCys: 0.435 ± 0.4
0.869TrpAsp: 0.869 ± 0.46
1.304TrpGlu: 1.304 ± 0.321
0.0TrpPhe: 0.0 ± 0.0
0.435TrpGly: 0.435 ± 0.329
0.435TrpHis: 0.435 ± 0.443
0.869TrpIle: 0.869 ± 0.46
0.435TrpLys: 0.435 ± 0.405
0.435TrpLeu: 0.435 ± 0.329
0.435TrpMet: 0.435 ± 0.405
0.0TrpAsn: 0.0 ± 0.0
0.435TrpPro: 0.435 ± 0.406
0.869TrpGln: 0.869 ± 0.658
0.435TrpArg: 0.435 ± 0.405
0.435TrpSer: 0.435 ± 0.329
0.869TrpThr: 0.869 ± 0.396
0.435TrpVal: 0.435 ± 0.329
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.738TyrAla: 1.738 ± 0.272
0.0TyrCys: 0.0 ± 0.0
2.173TyrAsp: 2.173 ± 1.134
2.608TyrGlu: 2.608 ± 0.927
1.738TyrPhe: 1.738 ± 1.316
1.304TyrGly: 1.304 ± 0.514
1.304TyrHis: 1.304 ± 0.739
3.911TyrIle: 3.911 ± 0.773
4.781TyrLys: 4.781 ± 0.774
3.477TyrLeu: 3.477 ± 1.151
0.435TyrMet: 0.435 ± 0.406
1.304TyrAsn: 1.304 ± 0.425
1.304TyrPro: 1.304 ± 0.425
0.435TyrGln: 0.435 ± 0.329
2.173TyrArg: 2.173 ± 0.976
3.477TyrSer: 3.477 ± 1.112
2.608TyrThr: 2.608 ± 0.745
2.173TyrVal: 2.173 ± 0.756
0.435TyrTrp: 0.435 ± 0.405
1.304TyrTyr: 1.304 ± 1.03
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2302 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski