Amino acid dipepetide frequency for Gokushovirinae Fen672_31

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.83AlaAla: 12.83 ± 3.924
1.426AlaCys: 1.426 ± 1.08
5.702AlaAsp: 5.702 ± 1.56
4.277AlaGlu: 4.277 ± 0.572
3.564AlaPhe: 3.564 ± 1.567
7.84AlaGly: 7.84 ± 2.131
1.426AlaHis: 1.426 ± 0.576
7.128AlaIle: 7.128 ± 2.06
4.277AlaLys: 4.277 ± 2.38
4.277AlaLeu: 4.277 ± 1.475
2.851AlaMet: 2.851 ± 1.839
3.564AlaAsn: 3.564 ± 1.5
8.553AlaPro: 8.553 ± 4.204
2.851AlaGln: 2.851 ± 1.273
4.989AlaArg: 4.989 ± 1.094
9.266AlaSer: 9.266 ± 1.878
5.702AlaThr: 5.702 ± 2.305
7.128AlaVal: 7.128 ± 3.278
0.713AlaTrp: 0.713 ± 0.993
3.564AlaTyr: 3.564 ± 1.097
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.426CysAsp: 1.426 ± 0.943
0.0CysGlu: 0.0 ± 0.0
1.426CysPhe: 1.426 ± 1.007
2.138CysGly: 2.138 ± 1.09
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.426CysLeu: 1.426 ± 0.987
1.426CysMet: 1.426 ± 0.576
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.426CysArg: 1.426 ± 1.08
0.713CysSer: 0.713 ± 0.459
0.713CysThr: 0.713 ± 0.459
0.713CysVal: 0.713 ± 0.606
0.0CysTrp: 0.0 ± 0.0
0.713CysTyr: 0.713 ± 0.459
0.0CysXaa: 0.0 ± 0.0
Asp
6.415AspAla: 6.415 ± 0.951
0.713AspCys: 0.713 ± 0.459
0.713AspAsp: 0.713 ± 0.899
1.426AspGlu: 1.426 ± 0.892
5.702AspPhe: 5.702 ± 2.629
2.851AspGly: 2.851 ± 1.152
1.426AspHis: 1.426 ± 1.212
0.0AspIle: 0.0 ± 0.0
2.138AspLys: 2.138 ± 1.235
2.138AspLeu: 2.138 ± 0.868
2.138AspMet: 2.138 ± 0.802
7.128AspAsn: 7.128 ± 0.977
2.138AspPro: 2.138 ± 1.235
2.851AspGln: 2.851 ± 1.267
3.564AspArg: 3.564 ± 1.634
4.277AspSer: 4.277 ± 0.974
2.851AspThr: 2.851 ± 0.76
3.564AspVal: 3.564 ± 1.386
0.0AspTrp: 0.0 ± 0.0
1.426AspTyr: 1.426 ± 0.919
0.0AspXaa: 0.0 ± 0.0
Glu
1.426GluAla: 1.426 ± 0.892
1.426GluCys: 1.426 ± 1.166
0.713GluAsp: 0.713 ± 0.899
1.426GluGlu: 1.426 ± 1.568
2.851GluPhe: 2.851 ± 1.777
0.0GluGly: 0.0 ± 0.0
2.138GluHis: 2.138 ± 0.636
0.713GluIle: 0.713 ± 0.459
3.564GluLys: 3.564 ± 1.497
3.564GluLeu: 3.564 ± 1.38
0.0GluMet: 0.0 ± 0.0
0.713GluAsn: 0.713 ± 0.784
0.713GluPro: 0.713 ± 0.784
2.138GluGln: 2.138 ± 0.909
4.989GluArg: 4.989 ± 1.111
2.851GluSer: 2.851 ± 1.133
2.138GluThr: 2.138 ± 1.467
3.564GluVal: 3.564 ± 0.625
0.713GluTrp: 0.713 ± 0.606
2.138GluTyr: 2.138 ± 0.847
0.0GluXaa: 0.0 ± 0.0
Phe
2.851PheAla: 2.851 ± 1.407
0.0PheCys: 0.0 ± 0.0
4.989PheAsp: 4.989 ± 0.605
1.426PheGlu: 1.426 ± 1.212
2.138PhePhe: 2.138 ± 0.847
3.564PheGly: 3.564 ± 1.407
0.713PheHis: 0.713 ± 0.784
1.426PheIle: 1.426 ± 0.576
0.0PheLys: 0.0 ± 0.0
2.138PheLeu: 2.138 ± 1.378
1.426PheMet: 1.426 ± 0.585
2.851PheAsn: 2.851 ± 1.152
1.426PhePro: 1.426 ± 0.892
1.426PheGln: 1.426 ± 0.919
3.564PheArg: 3.564 ± 1.221
3.564PheSer: 3.564 ± 1.224
7.128PheThr: 7.128 ± 2.234
2.851PheVal: 2.851 ± 1.534
0.713PheTrp: 0.713 ± 0.459
4.277PheTyr: 4.277 ± 2.853
0.0PheXaa: 0.0 ± 0.0
Gly
8.553GlyAla: 8.553 ± 1.157
0.713GlyCys: 0.713 ± 0.606
4.277GlyAsp: 4.277 ± 1.595
2.138GlyGlu: 2.138 ± 0.868
1.426GlyPhe: 1.426 ± 0.576
9.266GlyGly: 9.266 ± 1.745
0.713GlyHis: 0.713 ± 0.639
3.564GlyIle: 3.564 ± 1.419
2.138GlyLys: 2.138 ± 0.891
7.128GlyLeu: 7.128 ± 1.652
2.138GlyMet: 2.138 ± 1.19
1.426GlyAsn: 1.426 ± 0.919
4.989GlyPro: 4.989 ± 2.02
2.851GlyGln: 2.851 ± 0.74
2.138GlyArg: 2.138 ± 0.636
5.702GlySer: 5.702 ± 0.924
4.989GlyThr: 4.989 ± 2.547
9.979GlyVal: 9.979 ± 1.495
0.0GlyTrp: 0.0 ± 0.0
2.851GlyTyr: 2.851 ± 1.291
0.0GlyXaa: 0.0 ± 0.0
His
2.138HisAla: 2.138 ± 1.051
0.713HisCys: 0.713 ± 0.459
2.138HisAsp: 2.138 ± 0.847
0.713HisGlu: 0.713 ± 0.606
0.713HisPhe: 0.713 ± 0.459
2.138HisGly: 2.138 ± 0.891
0.0HisHis: 0.0 ± 0.0
0.713HisIle: 0.713 ± 0.784
0.713HisLys: 0.713 ± 1.067
2.138HisLeu: 2.138 ± 1.09
0.713HisMet: 0.713 ± 0.459
0.713HisAsn: 0.713 ± 0.606
1.426HisPro: 1.426 ± 0.576
0.0HisGln: 0.0 ± 0.0
1.426HisArg: 1.426 ± 0.703
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.138HisTyr: 2.138 ± 1.378
0.0HisXaa: 0.0 ± 0.0
Ile
2.138IleAla: 2.138 ± 0.802
1.426IleCys: 1.426 ± 0.919
0.713IleAsp: 0.713 ± 0.459
1.426IleGlu: 1.426 ± 1.166
1.426IlePhe: 1.426 ± 0.919
6.415IleGly: 6.415 ± 2.305
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.426IleLys: 1.426 ± 1.212
0.713IleLeu: 0.713 ± 0.606
0.713IleMet: 0.713 ± 0.784
1.426IleAsn: 1.426 ± 0.919
2.851IlePro: 2.851 ± 1.838
2.851IleGln: 2.851 ± 1.291
2.138IleArg: 2.138 ± 1.524
2.851IleSer: 2.851 ± 1.268
2.851IleThr: 2.851 ± 1.446
2.138IleVal: 2.138 ± 0.953
1.426IleTrp: 1.426 ± 0.919
2.138IleTyr: 2.138 ± 1.097
0.0IleXaa: 0.0 ± 0.0
Lys
4.989LysAla: 4.989 ± 1.292
0.713LysCys: 0.713 ± 0.459
0.0LysAsp: 0.0 ± 0.0
3.564LysGlu: 3.564 ± 2.281
0.0LysPhe: 0.0 ± 0.0
1.426LysGly: 1.426 ± 1.026
1.426LysHis: 1.426 ± 1.007
1.426LysIle: 1.426 ± 0.576
2.851LysLys: 2.851 ± 2.347
2.851LysLeu: 2.851 ± 1.617
2.851LysMet: 2.851 ± 1.945
2.851LysAsn: 2.851 ± 2.138
3.564LysPro: 3.564 ± 2.952
0.713LysGln: 0.713 ± 0.639
3.564LysArg: 3.564 ± 1.216
3.564LysSer: 3.564 ± 2.075
2.138LysThr: 2.138 ± 1.916
2.851LysVal: 2.851 ± 1.681
0.0LysTrp: 0.0 ± 0.0
0.713LysTyr: 0.713 ± 0.606
0.0LysXaa: 0.0 ± 0.0
Leu
5.702LeuAla: 5.702 ± 1.129
0.0LeuCys: 0.0 ± 0.0
4.277LeuAsp: 4.277 ± 1.177
2.138LeuGlu: 2.138 ± 0.847
4.277LeuPhe: 4.277 ± 1.627
2.138LeuGly: 2.138 ± 1.097
1.426LeuHis: 1.426 ± 0.576
4.277LeuIle: 4.277 ± 1.693
2.138LeuLys: 2.138 ± 0.868
6.415LeuLeu: 6.415 ± 1.803
2.851LeuMet: 2.851 ± 1.768
2.138LeuAsn: 2.138 ± 0.909
6.415LeuPro: 6.415 ± 1.967
3.564LeuGln: 3.564 ± 1.374
3.564LeuArg: 3.564 ± 0.761
7.128LeuSer: 7.128 ± 1.84
5.702LeuThr: 5.702 ± 1.616
4.277LeuVal: 4.277 ± 1.009
0.713LeuTrp: 0.713 ± 0.606
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.138MetAla: 2.138 ± 1.467
0.713MetCys: 0.713 ± 0.993
2.138MetAsp: 2.138 ± 0.802
1.426MetGlu: 1.426 ± 1.166
2.138MetPhe: 2.138 ± 1.006
1.426MetGly: 1.426 ± 0.919
0.713MetHis: 0.713 ± 0.606
0.0MetIle: 0.0 ± 0.0
5.702MetLys: 5.702 ± 1.969
0.0MetLeu: 0.0 ± 0.0
2.138MetMet: 2.138 ± 1.235
2.138MetAsn: 2.138 ± 1.916
0.713MetPro: 0.713 ± 0.459
1.426MetGln: 1.426 ± 1.277
4.277MetArg: 4.277 ± 2.361
4.989MetSer: 4.989 ± 1.149
1.426MetThr: 1.426 ± 0.808
1.426MetVal: 1.426 ± 0.637
0.713MetTrp: 0.713 ± 0.459
0.713MetTyr: 0.713 ± 0.899
0.0MetXaa: 0.0 ± 0.0
Asn
2.138AsnAla: 2.138 ± 1.624
1.426AsnCys: 1.426 ± 1.212
2.138AsnAsp: 2.138 ± 1.062
2.138AsnGlu: 2.138 ± 0.909
0.713AsnPhe: 0.713 ± 0.459
1.426AsnGly: 1.426 ± 0.943
0.0AsnHis: 0.0 ± 0.0
0.713AsnIle: 0.713 ± 0.459
0.713AsnLys: 0.713 ± 0.639
7.84AsnLeu: 7.84 ± 3.099
3.564AsnMet: 3.564 ± 2.425
2.138AsnAsn: 2.138 ± 1.278
3.564AsnPro: 3.564 ± 1.712
4.277AsnGln: 4.277 ± 1.91
0.0AsnArg: 0.0 ± 0.0
2.851AsnSer: 2.851 ± 0.994
1.426AsnThr: 1.426 ± 0.808
2.138AsnVal: 2.138 ± 1.176
0.0AsnTrp: 0.0 ± 0.0
0.713AsnTyr: 0.713 ± 0.459
0.0AsnXaa: 0.0 ± 0.0
Pro
9.979ProAla: 9.979 ± 4.458
0.713ProCys: 0.713 ± 0.606
2.851ProAsp: 2.851 ± 0.76
1.426ProGlu: 1.426 ± 0.943
1.426ProPhe: 1.426 ± 1.166
6.415ProGly: 6.415 ± 1.967
1.426ProHis: 1.426 ± 0.943
4.277ProIle: 4.277 ± 1.48
1.426ProLys: 1.426 ± 0.703
2.851ProLeu: 2.851 ± 1.234
2.138ProMet: 2.138 ± 1.668
0.713ProAsn: 0.713 ± 0.784
2.851ProPro: 2.851 ± 1.152
4.989ProGln: 4.989 ± 1.723
2.138ProArg: 2.138 ± 0.847
3.564ProSer: 3.564 ± 1.712
4.989ProThr: 4.989 ± 1.518
4.989ProVal: 4.989 ± 1.013
0.713ProTrp: 0.713 ± 0.459
0.713ProTyr: 0.713 ± 0.993
0.0ProXaa: 0.0 ± 0.0
Gln
8.553GlnAla: 8.553 ± 2.73
0.713GlnCys: 0.713 ± 0.606
1.426GlnAsp: 1.426 ± 0.919
2.851GlnGlu: 2.851 ± 0.855
2.138GlnPhe: 2.138 ± 0.909
2.851GlnGly: 2.851 ± 1.291
0.0GlnHis: 0.0 ± 0.0
3.564GlnIle: 3.564 ± 1.661
2.138GlnLys: 2.138 ± 0.909
1.426GlnLeu: 1.426 ± 0.576
1.426GlnMet: 1.426 ± 0.988
2.851GlnAsn: 2.851 ± 1.273
1.426GlnPro: 1.426 ± 0.703
4.989GlnGln: 4.989 ± 3.689
2.851GlnArg: 2.851 ± 1.268
0.713GlnSer: 0.713 ± 0.639
3.564GlnThr: 3.564 ± 1.5
0.713GlnVal: 0.713 ± 0.459
1.426GlnTrp: 1.426 ± 0.576
0.713GlnTyr: 0.713 ± 0.459
0.0GlnXaa: 0.0 ± 0.0
Arg
4.989ArgAla: 4.989 ± 1.094
0.713ArgCys: 0.713 ± 0.606
2.851ArgAsp: 2.851 ± 1.152
1.426ArgGlu: 1.426 ± 1.277
2.851ArgPhe: 2.851 ± 1.035
5.702ArgGly: 5.702 ± 0.868
0.713ArgHis: 0.713 ± 0.459
3.564ArgIle: 3.564 ± 1.634
2.138ArgLys: 2.138 ± 1.395
7.128ArgLeu: 7.128 ± 2.979
0.713ArgMet: 0.713 ± 0.459
0.713ArgAsn: 0.713 ± 0.784
4.277ArgPro: 4.277 ± 2.245
2.851ArgGln: 2.851 ± 0.76
7.84ArgArg: 7.84 ± 5.181
5.702ArgSer: 5.702 ± 1.988
0.0ArgThr: 0.0 ± 0.0
4.277ArgVal: 4.277 ± 2.883
0.0ArgTrp: 0.0 ± 0.0
4.989ArgTyr: 4.989 ± 1.525
0.0ArgXaa: 0.0 ± 0.0
Ser
8.553SerAla: 8.553 ± 3.036
0.0SerCys: 0.0 ± 0.0
4.277SerAsp: 4.277 ± 2.873
2.138SerGlu: 2.138 ± 1.062
3.564SerPhe: 3.564 ± 2.133
7.128SerGly: 7.128 ± 1.882
2.138SerHis: 2.138 ± 1.378
2.138SerIle: 2.138 ± 0.909
3.564SerLys: 3.564 ± 1.784
2.851SerLeu: 2.851 ± 1.838
0.713SerMet: 0.713 ± 0.639
1.426SerAsn: 1.426 ± 0.637
2.851SerPro: 2.851 ± 0.855
2.851SerGln: 2.851 ± 1.291
6.415SerArg: 6.415 ± 2.034
7.128SerSer: 7.128 ± 6.127
7.84SerThr: 7.84 ± 2.913
4.989SerVal: 4.989 ± 1.769
2.138SerTrp: 2.138 ± 0.722
2.851SerTyr: 2.851 ± 0.76
0.0SerXaa: 0.0 ± 0.0
Thr
8.553ThrAla: 8.553 ± 3.176
0.713ThrCys: 0.713 ± 0.459
6.415ThrAsp: 6.415 ± 1.291
2.138ThrGlu: 2.138 ± 0.909
4.989ThrPhe: 4.989 ± 2.068
4.277ThrGly: 4.277 ± 1.746
0.713ThrHis: 0.713 ± 0.459
1.426ThrIle: 1.426 ± 0.637
2.138ThrLys: 2.138 ± 1.021
7.128ThrLeu: 7.128 ± 2.02
1.426ThrMet: 1.426 ± 0.637
0.713ThrAsn: 0.713 ± 0.639
4.989ThrPro: 4.989 ± 1.204
2.851ThrGln: 2.851 ± 0.994
4.277ThrArg: 4.277 ± 2.11
4.989ThrSer: 4.989 ± 1.204
7.128ThrThr: 7.128 ± 1.798
1.426ThrVal: 1.426 ± 0.576
0.0ThrTrp: 0.0 ± 0.0
1.426ThrTyr: 1.426 ± 0.576
0.0ThrXaa: 0.0 ± 0.0
Val
7.128ValAla: 7.128 ± 2.816
0.0ValCys: 0.0 ± 0.0
4.277ValAsp: 4.277 ± 1.568
1.426ValGlu: 1.426 ± 0.576
2.851ValPhe: 2.851 ± 0.938
6.415ValGly: 6.415 ± 1.522
1.426ValHis: 1.426 ± 1.342
2.138ValIle: 2.138 ± 0.868
2.851ValLys: 2.851 ± 1.877
4.989ValLeu: 4.989 ± 1.049
4.989ValMet: 4.989 ± 1.319
4.989ValAsn: 4.989 ± 1.81
5.702ValPro: 5.702 ± 2.126
0.713ValGln: 0.713 ± 0.639
3.564ValArg: 3.564 ± 1.907
2.851ValSer: 2.851 ± 1.8
3.564ValThr: 3.564 ± 1.167
7.84ValVal: 7.84 ± 1.55
0.0ValTrp: 0.0 ± 0.0
0.713ValTyr: 0.713 ± 0.459
0.0ValXaa: 0.0 ± 0.0
Trp
0.713TrpAla: 0.713 ± 0.606
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.426TrpPhe: 1.426 ± 0.576
1.426TrpGly: 1.426 ± 0.703
0.713TrpHis: 0.713 ± 0.459
0.0TrpIle: 0.0 ± 0.0
0.713TrpLys: 0.713 ± 0.606
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.713TrpAsn: 0.713 ± 0.459
1.426TrpPro: 1.426 ± 0.919
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.138TrpSer: 2.138 ± 0.953
0.713TrpThr: 0.713 ± 0.606
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.851TyrAla: 2.851 ± 1.667
0.0TyrCys: 0.0 ± 0.0
2.138TyrAsp: 2.138 ± 1.378
4.277TyrGlu: 4.277 ± 1.509
2.851TyrPhe: 2.851 ± 1.838
2.138TyrGly: 2.138 ± 1.09
1.426TyrHis: 1.426 ± 1.007
0.0TyrIle: 0.0 ± 0.0
1.426TyrLys: 1.426 ± 0.703
2.138TyrLeu: 2.138 ± 1.097
1.426TyrMet: 1.426 ± 0.615
0.713TyrAsn: 0.713 ± 0.459
0.713TyrPro: 0.713 ± 0.899
2.138TyrGln: 2.138 ± 0.909
0.713TyrArg: 0.713 ± 0.459
0.713TyrSer: 0.713 ± 0.899
2.851TyrThr: 2.851 ± 1.045
3.564TyrVal: 3.564 ± 1.374
0.713TyrTrp: 0.713 ± 0.606
1.426TyrTyr: 1.426 ± 0.943
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1404 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski