Amino acid dipepetide frequency for Talaromyces atroroseus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.679AlaAla: 8.679 ± 0.062	1.017AlaCys: 1.017 ± 0.017	4.202AlaAsp: 4.202 ± 0.031	5.02AlaGlu: 5.02 ± 0.045	3.155AlaPhe: 3.155 ± 0.027	5.527AlaGly: 5.527 ± 0.038	1.758AlaHis: 1.758 ± 0.021	4.544AlaIle: 4.544 ± 0.034	3.787AlaLys: 3.787 ± 0.033	7.622AlaLeu: 7.622 ± 0.048	1.888AlaMet: 1.888 ± 0.019	3.032AlaAsn: 3.032 ± 0.028	4.163AlaPro: 4.163 ± 0.041	3.276AlaGln: 3.276 ± 0.028	4.626AlaArg: 4.626 ± 0.032	7.305AlaSer: 7.305 ± 0.045	5.294AlaThr: 5.294 ± 0.037	5.378AlaVal: 5.378 ± 0.038	1.145AlaTrp: 1.145 ± 0.018	2.228AlaTyr: 2.228 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.884CysAla: 0.884 ± 0.014	0.22CysCys: 0.22 ± 0.008	0.645CysAsp: 0.645 ± 0.012	0.564CysGlu: 0.564 ± 0.012	0.534CysPhe: 0.534 ± 0.012	0.847CysGly: 0.847 ± 0.016	0.314CysHis: 0.314 ± 0.008	0.713CysIle: 0.713 ± 0.012	0.453CysLys: 0.453 ± 0.009	1.237CysLeu: 1.237 ± 0.018	0.258CysMet: 0.258 ± 0.008	0.414CysAsn: 0.414 ± 0.01	0.577CysPro: 0.577 ± 0.012	0.452CysGln: 0.452 ± 0.01	0.675CysArg: 0.675 ± 0.014	0.854CysSer: 0.854 ± 0.015	0.647CysThr: 0.647 ± 0.013	0.76CysVal: 0.76 ± 0.013	0.195CysTrp: 0.195 ± 0.008	0.355CysTyr: 0.355 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.61AspAla: 4.61 ± 0.027	0.59AspCys: 0.59 ± 0.012	4.333AspAsp: 4.333 ± 0.042	4.395AspGlu: 4.395 ± 0.036	2.267AspPhe: 2.267 ± 0.025	3.856AspGly: 3.856 ± 0.031	1.233AspHis: 1.233 ± 0.017	3.412AspIle: 3.412 ± 0.025	2.317AspLys: 2.317 ± 0.022	5.092AspLeu: 5.092 ± 0.038	1.271AspMet: 1.271 ± 0.016	2.092AspAsn: 2.092 ± 0.019	3.064AspPro: 3.064 ± 0.028	1.903AspGln: 1.903 ± 0.022	2.959AspArg: 2.959 ± 0.028	4.342AspSer: 4.342 ± 0.034	3.014AspThr: 3.014 ± 0.025	3.697AspVal: 3.697 ± 0.028	0.856AspTrp: 0.856 ± 0.014	1.744AspTyr: 1.744 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.088GluAla: 5.088 ± 0.039	0.572GluCys: 0.572 ± 0.011	4.2GluAsp: 4.2 ± 0.037	5.442GluGlu: 5.442 ± 0.052	2.017GluPhe: 2.017 ± 0.022	3.462GluGly: 3.462 ± 0.028	1.38GluHis: 1.38 ± 0.016	3.334GluIle: 3.334 ± 0.028	3.76GluLys: 3.76 ± 0.034	5.198GluLeu: 5.198 ± 0.037	1.376GluMet: 1.376 ± 0.019	2.621GluAsn: 2.621 ± 0.028	2.563GluPro: 2.563 ± 0.035	2.596GluGln: 2.596 ± 0.026	3.781GluArg: 3.781 ± 0.034	4.526GluSer: 4.526 ± 0.031	3.627GluThr: 3.627 ± 0.03	3.456GluVal: 3.456 ± 0.03	0.865GluTrp: 0.865 ± 0.014	1.775GluTyr: 1.775 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.079PheAla: 3.079 ± 0.027	0.551PheCys: 0.551 ± 0.012	2.316PheAsp: 2.316 ± 0.021	2.2PheGlu: 2.2 ± 0.022	1.679PhePhe: 1.679 ± 0.023	2.802PheGly: 2.802 ± 0.031	0.929PheHis: 0.929 ± 0.014	1.969PheIle: 1.969 ± 0.024	1.449PheLys: 1.449 ± 0.019	3.646PheLeu: 3.646 ± 0.032	0.809PheMet: 0.809 ± 0.013	1.475PheAsn: 1.475 ± 0.017	1.948PhePro: 1.948 ± 0.021	1.451PheGln: 1.451 ± 0.017	1.978PheArg: 1.978 ± 0.022	3.192PheSer: 3.192 ± 0.028	2.185PheThr: 2.185 ± 0.021	2.477PheVal: 2.477 ± 0.025	0.653PheTrp: 0.653 ± 0.014	1.187PheTyr: 1.187 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.902GlyAla: 4.902 ± 0.036	0.8GlyCys: 0.8 ± 0.016	3.507GlyAsp: 3.507 ± 0.027	3.415GlyGlu: 3.415 ± 0.028	2.802GlyPhe: 2.802 ± 0.027	5.351GlyGly: 5.351 ± 0.057	1.606GlyHis: 1.606 ± 0.02	3.772GlyIle: 3.772 ± 0.03	3.208GlyLys: 3.208 ± 0.029	6.052GlyLeu: 6.052 ± 0.044	1.434GlyMet: 1.434 ± 0.018	2.576GlyAsn: 2.576 ± 0.023	3.0GlyPro: 3.0 ± 0.031	2.477GlyGln: 2.477 ± 0.027	3.803GlyArg: 3.803 ± 0.035	5.534GlySer: 5.534 ± 0.043	3.815GlyThr: 3.815 ± 0.03	4.233GlyVal: 4.233 ± 0.034	1.093GlyTrp: 1.093 ± 0.016	2.205GlyTyr: 2.205 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	1.837HisAla: 1.837 ± 0.02	0.314HisCys: 0.314 ± 0.008	1.347HisAsp: 1.347 ± 0.018	1.375HisGlu: 1.375 ± 0.017	0.927HisPhe: 0.927 ± 0.014	1.694HisGly: 1.694 ± 0.019	0.889HisHis: 0.889 ± 0.018	1.295HisIle: 1.295 ± 0.018	0.908HisLys: 0.908 ± 0.014	2.207HisLeu: 2.207 ± 0.025	0.473HisMet: 0.473 ± 0.01	0.917HisAsn: 0.917 ± 0.014	1.55HisPro: 1.55 ± 0.021	1.006HisGln: 1.006 ± 0.015	1.551HisArg: 1.551 ± 0.016	1.937HisSer: 1.937 ± 0.02	1.283HisThr: 1.283 ± 0.017	1.457HisVal: 1.457 ± 0.019	0.334HisTrp: 0.334 ± 0.009	0.713HisTyr: 0.713 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.422IleAla: 4.422 ± 0.03	0.78IleCys: 0.78 ± 0.013	3.154IleAsp: 3.154 ± 0.023	3.111IleGlu: 3.111 ± 0.028	2.159IlePhe: 2.159 ± 0.025	3.36IleGly: 3.36 ± 0.035	1.3IleHis: 1.3 ± 0.015	2.824IleIle: 2.824 ± 0.029	2.226IleLys: 2.226 ± 0.021	4.924IleLeu: 4.924 ± 0.041	1.078IleMet: 1.078 ± 0.014	2.027IleAsn: 2.027 ± 0.02	3.204IlePro: 3.204 ± 0.025	2.08IleGln: 2.08 ± 0.022	2.935IleArg: 2.935 ± 0.027	4.395IleSer: 4.395 ± 0.033	3.057IleThr: 3.057 ± 0.029	3.396IleVal: 3.396 ± 0.025	0.756IleTrp: 0.756 ± 0.014	1.585IleTyr: 1.585 ± 0.019	0.001IleXaa: 0.001 ± 0.0
Lys	4.009LysAla: 4.009 ± 0.031	0.463LysCys: 0.463 ± 0.01	2.611LysAsp: 2.611 ± 0.025	3.361LysGlu: 3.361 ± 0.034	1.473LysPhe: 1.473 ± 0.016	2.735LysGly: 2.735 ± 0.023	1.106LysHis: 1.106 ± 0.014	2.374LysIle: 2.374 ± 0.024	3.156LysLys: 3.156 ± 0.044	4.021LysLeu: 4.021 ± 0.034	0.937LysMet: 0.937 ± 0.015	1.844LysAsn: 1.844 ± 0.021	2.525LysPro: 2.525 ± 0.023	1.888LysGln: 1.888 ± 0.018	3.309LysArg: 3.309 ± 0.033	3.589LysSer: 3.589 ± 0.032	2.793LysThr: 2.793 ± 0.028	2.696LysVal: 2.696 ± 0.023	0.661LysTrp: 0.661 ± 0.013	1.445LysTyr: 1.445 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	7.715LeuAla: 7.715 ± 0.042	1.171LeuCys: 1.171 ± 0.019	5.305LeuAsp: 5.305 ± 0.034	5.552LeuGlu: 5.552 ± 0.04	3.498LeuPhe: 3.498 ± 0.03	5.859LeuGly: 5.859 ± 0.035	2.264LeuHis: 2.264 ± 0.02	4.264LeuIle: 4.264 ± 0.037	4.15LeuLys: 4.15 ± 0.036	8.645LeuLeu: 8.645 ± 0.066	1.772LeuMet: 1.772 ± 0.019	3.372LeuAsn: 3.372 ± 0.028	5.351LeuPro: 5.351 ± 0.037	3.956LeuGln: 3.956 ± 0.032	5.706LeuArg: 5.706 ± 0.033	7.828LeuSer: 7.828 ± 0.045	4.861LeuThr: 4.861 ± 0.034	5.465LeuVal: 5.465 ± 0.039	1.209LeuTrp: 1.209 ± 0.016	2.515LeuTyr: 2.515 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.166MetAla: 2.166 ± 0.022	0.239MetCys: 0.239 ± 0.007	1.183MetAsp: 1.183 ± 0.017	1.197MetGlu: 1.197 ± 0.018	0.747MetPhe: 0.747 ± 0.013	1.335MetGly: 1.335 ± 0.018	0.473MetHis: 0.473 ± 0.01	1.05MetIle: 1.05 ± 0.013	0.965MetLys: 0.965 ± 0.014	1.836MetLeu: 1.836 ± 0.021	0.526MetMet: 0.526 ± 0.01	0.835MetAsn: 0.835 ± 0.012	1.198MetPro: 1.198 ± 0.015	0.859MetGln: 0.859 ± 0.012	1.182MetArg: 1.182 ± 0.015	1.861MetSer: 1.861 ± 0.017	1.267MetThr: 1.267 ± 0.017	1.245MetVal: 1.245 ± 0.017	0.266MetTrp: 0.266 ± 0.008	0.51MetTyr: 0.51 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.298AsnAla: 3.298 ± 0.026	0.439AsnCys: 0.439 ± 0.01	2.199AsnAsp: 2.199 ± 0.02	2.266AsnGlu: 2.266 ± 0.022	1.433AsnPhe: 1.433 ± 0.017	2.988AsnGly: 2.988 ± 0.031	0.942AsnHis: 0.942 ± 0.013	2.332AsnIle: 2.332 ± 0.02	1.669AsnLys: 1.669 ± 0.019	3.402AsnLeu: 3.402 ± 0.024	0.855AsnMet: 0.855 ± 0.014	1.979AsnAsn: 1.979 ± 0.029	2.423AsnPro: 2.423 ± 0.027	1.421AsnGln: 1.421 ± 0.02	2.066AsnArg: 2.066 ± 0.021	3.088AsnSer: 3.088 ± 0.026	2.406AsnThr: 2.406 ± 0.025	2.474AsnVal: 2.474 ± 0.023	0.556AsnTrp: 0.556 ± 0.011	1.147AsnTyr: 1.147 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.71ProAla: 4.71 ± 0.046	0.469ProCys: 0.469 ± 0.01	3.001ProAsp: 3.001 ± 0.022	3.69ProGlu: 3.69 ± 0.034	2.041ProPhe: 2.041 ± 0.022	3.537ProGly: 3.537 ± 0.032	1.238ProHis: 1.238 ± 0.017	2.62ProIle: 2.62 ± 0.023	2.409ProLys: 2.409 ± 0.025	4.596ProLeu: 4.596 ± 0.032	0.976ProMet: 0.976 ± 0.015	2.132ProAsn: 2.132 ± 0.024	4.483ProPro: 4.483 ± 0.065	2.313ProGln: 2.313 ± 0.03	3.16ProArg: 3.16 ± 0.029	5.947ProSer: 5.947 ± 0.045	3.662ProThr: 3.662 ± 0.03	3.451ProVal: 3.451 ± 0.029	0.712ProTrp: 0.712 ± 0.012	1.51ProTyr: 1.51 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.303GlnAla: 3.303 ± 0.029	0.411GlnCys: 0.411 ± 0.008	2.047GlnAsp: 2.047 ± 0.019	2.433GlnGlu: 2.433 ± 0.026	1.344GlnPhe: 1.344 ± 0.016	2.335GlnGly: 2.335 ± 0.024	1.097GlnHis: 1.097 ± 0.017	2.008GlnIle: 2.008 ± 0.022	2.07GlnLys: 2.07 ± 0.022	3.596GlnLeu: 3.596 ± 0.028	0.861GlnMet: 0.861 ± 0.014	1.733GlnAsn: 1.733 ± 0.018	2.422GlnPro: 2.422 ± 0.029	2.681GlnGln: 2.681 ± 0.046	2.675GlnArg: 2.675 ± 0.028	3.363GlnSer: 3.363 ± 0.036	2.426GlnThr: 2.426 ± 0.021	2.187GlnVal: 2.187 ± 0.02	0.579GlnTrp: 0.579 ± 0.011	1.236GlnTyr: 1.236 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.422ArgAla: 4.422 ± 0.033	0.647ArgCys: 0.647 ± 0.014	3.273ArgAsp: 3.273 ± 0.03	3.763ArgGlu: 3.763 ± 0.031	2.146ArgPhe: 2.146 ± 0.02	3.466ArgGly: 3.466 ± 0.032	1.535ArgHis: 1.535 ± 0.019	3.0ArgIle: 3.0 ± 0.026	3.424ArgLys: 3.424 ± 0.032	5.55ArgLeu: 5.55 ± 0.034	1.222ArgMet: 1.222 ± 0.016	2.383ArgAsn: 2.383 ± 0.025	3.224ArgPro: 3.224 ± 0.034	2.651ArgGln: 2.651 ± 0.028	4.94ArgArg: 4.94 ± 0.045	4.671ArgSer: 4.671 ± 0.038	3.176ArgThr: 3.176 ± 0.027	3.3ArgVal: 3.3 ± 0.026	0.88ArgTrp: 0.88 ± 0.015	1.712ArgTyr: 1.712 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.708SerAla: 6.708 ± 0.043	0.838SerCys: 0.838 ± 0.018	4.425SerAsp: 4.425 ± 0.033	4.391SerGlu: 4.391 ± 0.028	3.189SerPhe: 3.189 ± 0.028	5.456SerGly: 5.456 ± 0.039	2.078SerHis: 2.078 ± 0.023	4.433SerIle: 4.433 ± 0.031	3.762SerLys: 3.762 ± 0.035	7.795SerLeu: 7.795 ± 0.043	1.731SerMet: 1.731 ± 0.018	3.393SerAsn: 3.393 ± 0.031	5.304SerPro: 5.304 ± 0.049	3.517SerGln: 3.517 ± 0.03	5.097SerArg: 5.097 ± 0.043	10.015SerSer: 10.015 ± 0.099	5.976SerThr: 5.976 ± 0.052	4.864SerVal: 4.864 ± 0.031	1.107SerTrp: 1.107 ± 0.016	2.238SerTyr: 2.238 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.311ThrAla: 5.311 ± 0.036	0.688ThrCys: 0.688 ± 0.012	2.924ThrAsp: 2.924 ± 0.025	3.235ThrGlu: 3.235 ± 0.03	2.253ThrPhe: 2.253 ± 0.023	4.108ThrGly: 4.108 ± 0.032	1.292ThrHis: 1.292 ± 0.016	3.244ThrIle: 3.244 ± 0.027	2.601ThrLys: 2.601 ± 0.023	5.29ThrLeu: 5.29 ± 0.033	1.179ThrMet: 1.179 ± 0.014	2.304ThrAsn: 2.304 ± 0.024	4.071ThrPro: 4.071 ± 0.036	2.108ThrGln: 2.108 ± 0.019	3.028ThrArg: 3.028 ± 0.027	5.662ThrSer: 5.662 ± 0.045	4.594ThrThr: 4.594 ± 0.049	3.86ThrVal: 3.86 ± 0.03	0.86ThrTrp: 0.86 ± 0.014	1.684ThrTyr: 1.684 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.182ValAla: 5.182 ± 0.035	0.786ValCys: 0.786 ± 0.013	3.765ValAsp: 3.765 ± 0.027	3.801ValGlu: 3.801 ± 0.035	2.529ValPhe: 2.529 ± 0.028	3.867ValGly: 3.867 ± 0.034	1.425ValHis: 1.425 ± 0.017	3.214ValIle: 3.214 ± 0.027	2.769ValLys: 2.769 ± 0.027	5.59ValLeu: 5.59 ± 0.035	1.269ValMet: 1.269 ± 0.017	2.376ValAsn: 2.376 ± 0.025	3.459ValPro: 3.459 ± 0.03	2.41ValGln: 2.41 ± 0.023	3.325ValArg: 3.325 ± 0.027	4.942ValSer: 4.942 ± 0.03	3.617ValThr: 3.617 ± 0.03	4.234ValVal: 4.234 ± 0.036	0.825ValTrp: 0.825 ± 0.012	1.782ValTyr: 1.782 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.103TrpAla: 1.103 ± 0.017	0.181TrpCys: 0.181 ± 0.006	0.873TrpAsp: 0.873 ± 0.014	0.816TrpGlu: 0.816 ± 0.011	0.529TrpPhe: 0.529 ± 0.012	0.86TrpGly: 0.86 ± 0.015	0.36TrpHis: 0.36 ± 0.008	0.797TrpIle: 0.797 ± 0.015	0.789TrpLys: 0.789 ± 0.014	1.36TrpLeu: 1.36 ± 0.02	0.361TrpMet: 0.361 ± 0.009	0.673TrpAsn: 0.673 ± 0.011	0.59TrpPro: 0.59 ± 0.01	0.568TrpGln: 0.568 ± 0.011	0.916TrpArg: 0.916 ± 0.014	1.045TrpSer: 1.045 ± 0.013	0.903TrpThr: 0.903 ± 0.016	0.829TrpVal: 0.829 ± 0.016	0.272TrpTrp: 0.272 ± 0.008	0.444TrpTyr: 0.444 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.221TyrAla: 2.221 ± 0.024	0.421TyrCys: 0.421 ± 0.01	1.74TyrAsp: 1.74 ± 0.02	1.614TyrGlu: 1.614 ± 0.019	1.255TyrPhe: 1.255 ± 0.017	2.143TyrGly: 2.143 ± 0.026	0.794TyrHis: 0.794 ± 0.014	1.576TyrIle: 1.576 ± 0.017	1.125TyrLys: 1.125 ± 0.015	2.797TyrLeu: 2.797 ± 0.028	0.663TyrMet: 0.663 ± 0.012	1.206TyrAsn: 1.206 ± 0.015	1.537TyrPro: 1.537 ± 0.021	1.192TyrGln: 1.192 ± 0.017	1.673TyrArg: 1.673 ± 0.019	2.221TyrSer: 2.221 ± 0.022	1.688TyrThr: 1.688 ± 0.02	1.706TyrVal: 1.706 ± 0.016	0.443TyrTrp: 0.443 ± 0.009	1.026TyrTyr: 1.026 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9520 proteins (5014686 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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