Amino acid dipepetide frequency for Chamaesiphon minutus (strain ATCC 27169 / PCC 6605)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.986AlaAla: 8.986 ± 0.092	0.85AlaCys: 0.85 ± 0.022	4.789AlaAsp: 4.789 ± 0.058	5.199AlaGlu: 5.199 ± 0.063	2.752AlaPhe: 2.752 ± 0.048	5.937AlaGly: 5.937 ± 0.076	1.497AlaHis: 1.497 ± 0.032	8.219AlaIle: 8.219 ± 0.079	4.432AlaLys: 4.432 ± 0.052	8.022AlaLeu: 8.022 ± 0.077	1.916AlaMet: 1.916 ± 0.037	3.729AlaAsn: 3.729 ± 0.059	3.47AlaPro: 3.47 ± 0.05	4.29AlaGln: 4.29 ± 0.059	4.131AlaArg: 4.131 ± 0.055	4.989AlaSer: 4.989 ± 0.061	5.679AlaThr: 5.679 ± 0.076	5.422AlaVal: 5.422 ± 0.056	1.057AlaTrp: 1.057 ± 0.032	2.363AlaTyr: 2.363 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.734CysAla: 0.734 ± 0.022	0.179CysCys: 0.179 ± 0.01	0.614CysAsp: 0.614 ± 0.02	0.586CysGlu: 0.586 ± 0.02	0.403CysPhe: 0.403 ± 0.017	0.842CysGly: 0.842 ± 0.024	0.301CysHis: 0.301 ± 0.014	0.608CysIle: 0.608 ± 0.019	0.36CysLys: 0.36 ± 0.014	1.249CysLeu: 1.249 ± 0.033	0.183CysMet: 0.183 ± 0.01	0.385CysAsn: 0.385 ± 0.014	0.539CysPro: 0.539 ± 0.018	0.671CysGln: 0.671 ± 0.019	0.567CysArg: 0.567 ± 0.019	0.591CysSer: 0.591 ± 0.017	0.527CysThr: 0.527 ± 0.016	0.59CysVal: 0.59 ± 0.02	0.189CysTrp: 0.189 ± 0.009	0.361CysTyr: 0.361 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.988AspAla: 3.988 ± 0.05	0.638AspCys: 0.638 ± 0.02	2.538AspAsp: 2.538 ± 0.055	2.913AspGlu: 2.913 ± 0.047	2.302AspPhe: 2.302 ± 0.04	3.658AspGly: 3.658 ± 0.063	0.457AspHis: 0.457 ± 0.017	3.312AspIle: 3.312 ± 0.045	2.288AspLys: 2.288 ± 0.044	7.114AspLeu: 7.114 ± 0.08	0.785AspMet: 0.785 ± 0.022	2.04AspAsn: 2.04 ± 0.037	2.856AspPro: 2.856 ± 0.048	0.683AspGln: 0.683 ± 0.025	7.34AspArg: 7.34 ± 0.092	2.978AspSer: 2.978 ± 0.044	2.689AspThr: 2.689 ± 0.048	3.066AspVal: 3.066 ± 0.052	0.947AspTrp: 0.947 ± 0.024	1.944AspTyr: 1.944 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	4.576GluAla: 4.576 ± 0.058	0.556GluCys: 0.556 ± 0.02	2.56GluAsp: 2.56 ± 0.043	2.794GluGlu: 2.794 ± 0.051	2.283GluPhe: 2.283 ± 0.04	2.843GluGly: 2.843 ± 0.046	1.18GluHis: 1.18 ± 0.029	4.973GluIle: 4.973 ± 0.067	2.364GluLys: 2.364 ± 0.042	7.013GluLeu: 7.013 ± 0.079	1.283GluMet: 1.283 ± 0.028	2.054GluAsn: 2.054 ± 0.034	2.344GluPro: 2.344 ± 0.036	2.905GluGln: 2.905 ± 0.049	4.005GluArg: 4.005 ± 0.06	3.462GluSer: 3.462 ± 0.05	3.136GluThr: 3.136 ± 0.048	3.661GluVal: 3.661 ± 0.048	0.802GluTrp: 0.802 ± 0.024	1.867GluTyr: 1.867 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.179PheAla: 3.179 ± 0.049	0.507PheCys: 0.507 ± 0.019	2.652PheAsp: 2.652 ± 0.039	2.037PheGlu: 2.037 ± 0.037	1.445PhePhe: 1.445 ± 0.033	2.957PheGly: 2.957 ± 0.053	0.698PheHis: 0.698 ± 0.021	2.26PheIle: 2.26 ± 0.04	1.603PheLys: 1.603 ± 0.032	3.543PheLeu: 3.543 ± 0.049	0.694PheMet: 0.694 ± 0.023	1.682PheAsn: 1.682 ± 0.032	1.685PhePro: 1.685 ± 0.034	1.646PheGln: 1.646 ± 0.035	1.703PheArg: 1.703 ± 0.029	2.577PheSer: 2.577 ± 0.047	2.309PheThr: 2.309 ± 0.037	2.27PheVal: 2.27 ± 0.034	0.659PheTrp: 0.659 ± 0.022	1.259PheTyr: 1.259 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	5.304GlyAla: 5.304 ± 0.074	0.84GlyCys: 0.84 ± 0.023	3.62GlyAsp: 3.62 ± 0.064	3.825GlyGlu: 3.825 ± 0.051	2.802GlyPhe: 2.802 ± 0.04	4.887GlyGly: 4.887 ± 0.098	1.206GlyHis: 1.206 ± 0.029	5.233GlyIle: 5.233 ± 0.062	4.082GlyLys: 4.082 ± 0.053	6.722GlyLeu: 6.722 ± 0.071	1.699GlyMet: 1.699 ± 0.032	3.069GlyAsn: 3.069 ± 0.088	0.966GlyPro: 0.966 ± 0.028	2.678GlyGln: 2.678 ± 0.041	3.302GlyArg: 3.302 ± 0.045	4.312GlySer: 4.312 ± 0.069	4.123GlyThr: 4.123 ± 0.069	4.562GlyVal: 4.562 ± 0.06	1.119GlyTrp: 1.119 ± 0.028	2.45GlyTyr: 2.45 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	1.187HisAla: 1.187 ± 0.029	0.282HisCys: 0.282 ± 0.013	0.862HisAsp: 0.862 ± 0.027	0.85HisGlu: 0.85 ± 0.025	0.783HisPhe: 0.783 ± 0.022	1.151HisGly: 1.151 ± 0.03	0.7HisHis: 0.7 ± 0.026	1.015HisIle: 1.015 ± 0.026	0.717HisLys: 0.717 ± 0.02	2.22HisLeu: 2.22 ± 0.04	0.264HisMet: 0.264 ± 0.014	0.698HisAsn: 0.698 ± 0.021	1.424HisPro: 1.424 ± 0.033	1.289HisGln: 1.289 ± 0.028	1.275HisArg: 1.275 ± 0.026	1.208HisSer: 1.208 ± 0.028	0.974HisThr: 0.974 ± 0.028	0.879HisVal: 0.879 ± 0.024	0.33HisTrp: 0.33 ± 0.014	0.64HisTyr: 0.64 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	8.056IleAla: 8.056 ± 0.075	0.843IleCys: 0.843 ± 0.023	5.322IleAsp: 5.322 ± 0.059	5.101IleGlu: 5.101 ± 0.055	2.492IlePhe: 2.492 ± 0.044	5.305IleGly: 5.305 ± 0.06	1.33IleHis: 1.33 ± 0.032	3.63IleIle: 3.63 ± 0.055	2.703IleLys: 2.703 ± 0.041	6.654IleLeu: 6.654 ± 0.074	0.887IleMet: 0.887 ± 0.022	2.506IleAsn: 2.506 ± 0.039	3.595IlePro: 3.595 ± 0.049	2.932IleGln: 2.932 ± 0.038	3.105IleArg: 3.105 ± 0.047	4.597IleSer: 4.597 ± 0.057	3.41IleThr: 3.41 ± 0.048	5.214IleVal: 5.214 ± 0.064	0.921IleTrp: 0.921 ± 0.026	2.088IleTyr: 2.088 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.466LysAla: 3.466 ± 0.053	0.356LysCys: 0.356 ± 0.014	2.078LysAsp: 2.078 ± 0.039	2.134LysGlu: 2.134 ± 0.046	1.829LysPhe: 1.829 ± 0.033	2.339LysGly: 2.339 ± 0.039	0.816LysHis: 0.816 ± 0.023	3.694LysIle: 3.694 ± 0.048	1.975LysLys: 1.975 ± 0.04	5.522LysLeu: 5.522 ± 0.063	1.017LysMet: 1.017 ± 0.022	1.718LysAsn: 1.718 ± 0.032	2.239LysPro: 2.239 ± 0.036	2.521LysGln: 2.521 ± 0.039	2.063LysArg: 2.063 ± 0.034	3.09LysSer: 3.09 ± 0.048	2.741LysThr: 2.741 ± 0.044	2.893LysVal: 2.893 ± 0.044	0.525LysTrp: 0.525 ± 0.019	1.525LysTyr: 1.525 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	10.693LeuAla: 10.693 ± 0.08	1.038LeuCys: 1.038 ± 0.023	6.266LeuAsp: 6.266 ± 0.068	6.304LeuGlu: 6.304 ± 0.068	3.643LeuPhe: 3.643 ± 0.052	7.344LeuGly: 7.344 ± 0.068	1.926LeuHis: 1.926 ± 0.037	6.374LeuIle: 6.374 ± 0.068	5.023LeuLys: 5.023 ± 0.051	10.862LeuLeu: 10.862 ± 0.112	2.214LeuMet: 2.214 ± 0.041	4.316LeuAsn: 4.316 ± 0.051	5.838LeuPro: 5.838 ± 0.062	5.223LeuGln: 5.223 ± 0.065	5.199LeuArg: 5.199 ± 0.062	7.368LeuSer: 7.368 ± 0.072	6.83LeuThr: 6.83 ± 0.08	7.088LeuVal: 7.088 ± 0.068	1.404LeuTrp: 1.404 ± 0.037	2.626LeuTyr: 2.626 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.839MetAla: 1.839 ± 0.035	0.157MetCys: 0.157 ± 0.01	0.8MetAsp: 0.8 ± 0.022	0.967MetGlu: 0.967 ± 0.025	0.618MetPhe: 0.618 ± 0.022	1.457MetGly: 1.457 ± 0.031	0.317MetHis: 0.317 ± 0.016	0.865MetIle: 0.865 ± 0.024	0.964MetLys: 0.964 ± 0.027	2.139MetLeu: 2.139 ± 0.038	0.56MetMet: 0.56 ± 0.022	0.92MetAsn: 0.92 ± 0.022	1.061MetPro: 1.061 ± 0.025	0.911MetGln: 0.911 ± 0.022	1.026MetArg: 1.026 ± 0.026	1.649MetSer: 1.649 ± 0.031	1.47MetThr: 1.47 ± 0.028	1.289MetVal: 1.289 ± 0.028	0.206MetTrp: 0.206 ± 0.011	0.404MetTyr: 0.404 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.953AsnAla: 2.953 ± 0.045	0.482AsnCys: 0.482 ± 0.016	1.871AsnAsp: 1.871 ± 0.073	1.617AsnGlu: 1.617 ± 0.032	1.769AsnPhe: 1.769 ± 0.036	2.638AsnGly: 2.638 ± 0.05	0.749AsnHis: 0.749 ± 0.025	2.716AsnIle: 2.716 ± 0.043	1.49AsnLys: 1.49 ± 0.032	5.143AsnLeu: 5.143 ± 0.071	0.71AsnMet: 0.71 ± 0.019	1.874AsnAsn: 1.874 ± 0.043	2.688AsnPro: 2.688 ± 0.048	1.715AsnGln: 1.715 ± 0.035	2.597AsnArg: 2.597 ± 0.043	2.859AsnSer: 2.859 ± 0.041	2.239AsnThr: 2.239 ± 0.041	2.124AsnVal: 2.124 ± 0.034	0.74AsnTrp: 0.74 ± 0.021	1.533AsnTyr: 1.533 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	4.059ProAla: 4.059 ± 0.06	0.365ProCys: 0.365 ± 0.013	3.294ProAsp: 3.294 ± 0.045	3.467ProGlu: 3.467 ± 0.052	1.558ProPhe: 1.558 ± 0.028	2.718ProGly: 2.718 ± 0.051	1.013ProHis: 1.013 ± 0.028	3.463ProIle: 3.463 ± 0.048	2.08ProLys: 2.08 ± 0.036	4.632ProLeu: 4.632 ± 0.055	0.789ProMet: 0.789 ± 0.024	2.181ProAsn: 2.181 ± 0.04	2.419ProPro: 2.419 ± 0.046	2.597ProGln: 2.597 ± 0.047	1.737ProArg: 1.737 ± 0.037	2.95ProSer: 2.95 ± 0.049	3.451ProThr: 3.451 ± 0.056	3.042ProVal: 3.042 ± 0.052	0.557ProTrp: 0.557 ± 0.02	1.162ProTyr: 1.162 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.355GlnAla: 4.355 ± 0.066	0.339GlnCys: 0.339 ± 0.013	1.881GlnAsp: 1.881 ± 0.036	2.497GlnGlu: 2.497 ± 0.042	1.718GlnPhe: 1.718 ± 0.03	2.739GlnGly: 2.739 ± 0.04	0.955GlnHis: 0.955 ± 0.023	3.968GlnIle: 3.968 ± 0.056	2.089GlnLys: 2.089 ± 0.039	5.622GlnLeu: 5.622 ± 0.072	1.018GlnMet: 1.018 ± 0.026	1.714GlnAsn: 1.714 ± 0.031	2.611GlnPro: 2.611 ± 0.048	3.598GlnGln: 3.598 ± 0.065	2.687GlnArg: 2.687 ± 0.049	3.176GlnSer: 3.176 ± 0.048	2.928GlnThr: 2.928 ± 0.046	3.268GlnVal: 3.268 ± 0.047	0.643GlnTrp: 0.643 ± 0.021	1.092GlnTyr: 1.092 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	4.238ArgAla: 4.238 ± 0.055	0.565ArgCys: 0.565 ± 0.017	3.162ArgAsp: 3.162 ± 0.051	3.365ArgGlu: 3.365 ± 0.053	2.216ArgPhe: 2.216 ± 0.033	3.254ArgGly: 3.254 ± 0.046	1.167ArgHis: 1.167 ± 0.03	3.584ArgIle: 3.584 ± 0.046	2.175ArgLys: 2.175 ± 0.041	6.32ArgLeu: 6.32 ± 0.069	1.174ArgMet: 1.174 ± 0.027	2.065ArgAsn: 2.065 ± 0.033	2.075ArgPro: 2.075 ± 0.036	3.608ArgGln: 3.608 ± 0.058	3.048ArgArg: 3.048 ± 0.054	4.448ArgSer: 4.448 ± 0.046	2.803ArgThr: 2.803 ± 0.042	3.77ArgVal: 3.77 ± 0.051	0.864ArgTrp: 0.864 ± 0.024	1.915ArgTyr: 1.915 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.926SerAla: 4.926 ± 0.06	0.662SerCys: 0.662 ± 0.021	3.219SerAsp: 3.219 ± 0.053	3.454SerGlu: 3.454 ± 0.048	2.351SerPhe: 2.351 ± 0.037	4.766SerGly: 4.766 ± 0.062	1.296SerHis: 1.296 ± 0.028	5.449SerIle: 5.449 ± 0.06	2.827SerLys: 2.827 ± 0.04	7.134SerLeu: 7.134 ± 0.076	1.299SerMet: 1.299 ± 0.029	2.734SerAsn: 2.734 ± 0.049	3.381SerPro: 3.381 ± 0.054	3.444SerGln: 3.444 ± 0.048	3.117SerArg: 3.117 ± 0.047	4.454SerSer: 4.454 ± 0.06	3.98SerThr: 3.98 ± 0.05	3.941SerVal: 3.941 ± 0.053	0.853SerTrp: 0.853 ± 0.021	1.812SerTyr: 1.812 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.701ThrAla: 5.701 ± 0.068	0.529ThrCys: 0.529 ± 0.016	3.05ThrAsp: 3.05 ± 0.048	3.113ThrGlu: 3.113 ± 0.046	2.114ThrPhe: 2.114 ± 0.04	4.313ThrGly: 4.313 ± 0.072	1.058ThrHis: 1.058 ± 0.025	5.043ThrIle: 5.043 ± 0.067	2.52ThrLys: 2.52 ± 0.041	6.039ThrLeu: 6.039 ± 0.058	0.918ThrMet: 0.918 ± 0.021	2.472ThrAsn: 2.472 ± 0.046	3.618ThrPro: 3.618 ± 0.061	2.727ThrGln: 2.727 ± 0.042	2.427ThrArg: 2.427 ± 0.038	3.576ThrSer: 3.576 ± 0.055	3.88ThrThr: 3.88 ± 0.059	3.935ThrVal: 3.935 ± 0.067	0.717ThrTrp: 0.717 ± 0.02	1.589ThrTyr: 1.589 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	6.303ValAla: 6.303 ± 0.065	0.705ValCys: 0.705 ± 0.024	3.678ValAsp: 3.678 ± 0.049	4.089ValGlu: 4.089 ± 0.053	2.39ValPhe: 2.39 ± 0.043	4.669ValGly: 4.669 ± 0.056	0.978ValHis: 0.978 ± 0.024	3.708ValIle: 3.708 ± 0.046	3.293ValLys: 3.293 ± 0.048	5.969ValLeu: 5.969 ± 0.061	1.455ValMet: 1.455 ± 0.03	2.707ValAsn: 2.707 ± 0.04	2.906ValPro: 2.906 ± 0.048	2.299ValGln: 2.299 ± 0.042	3.473ValArg: 3.473 ± 0.054	4.261ValSer: 4.261 ± 0.052	3.964ValThr: 3.964 ± 0.055	4.581ValVal: 4.581 ± 0.058	0.85ValTrp: 0.85 ± 0.026	1.734ValTyr: 1.734 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	0.904TrpAla: 0.904 ± 0.022	0.188TrpCys: 0.188 ± 0.01	0.714TrpAsp: 0.714 ± 0.022	0.881TrpGlu: 0.881 ± 0.025	0.59TrpPhe: 0.59 ± 0.019	0.981TrpGly: 0.981 ± 0.026	0.384TrpHis: 0.384 ± 0.015	0.869TrpIle: 0.869 ± 0.022	0.55TrpLys: 0.55 ± 0.018	1.921TrpLeu: 1.921 ± 0.04	0.337TrpMet: 0.337 ± 0.014	0.544TrpAsn: 0.544 ± 0.018	0.208TrpPro: 0.208 ± 0.014	1.25TrpGln: 1.25 ± 0.033	0.835TrpArg: 0.835 ± 0.023	0.799TrpSer: 0.799 ± 0.023	0.673TrpThr: 0.673 ± 0.019	0.861TrpVal: 0.861 ± 0.022	0.267TrpTrp: 0.267 ± 0.013	0.437TrpTyr: 0.437 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.281TyrAla: 2.281 ± 0.038	0.399TyrCys: 0.399 ± 0.016	1.569TyrAsp: 1.569 ± 0.032	1.469TyrGlu: 1.469 ± 0.031	1.307TyrPhe: 1.307 ± 0.03	2.002TyrGly: 2.002 ± 0.038	0.716TyrHis: 0.716 ± 0.021	1.709TyrIle: 1.709 ± 0.03	1.008TyrLys: 1.008 ± 0.027	3.742TyrLeu: 3.742 ± 0.048	0.414TyrMet: 0.414 ± 0.014	1.097TyrAsn: 1.097 ± 0.03	1.611TyrPro: 1.611 ± 0.031	1.912TyrGln: 1.912 ± 0.037	2.178TyrArg: 2.178 ± 0.036	1.757TyrSer: 1.757 ± 0.035	1.532TyrThr: 1.532 ± 0.032	1.553TyrVal: 1.553 ± 0.03	0.543TyrTrp: 0.543 ± 0.018	1.054TyrTyr: 1.054 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5815 proteins (1743111 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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