Amino acid dipepetide frequency for Red clover powdery mildew-associated totivirus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.417AlaAla: 7.417 ± 0.823
1.236AlaCys: 1.236 ± 0.002
1.854AlaAsp: 1.854 ± 0.409
5.562AlaGlu: 5.562 ± 0.414
4.944AlaPhe: 4.944 ± 0.006
6.18AlaGly: 6.18 ± 1.635
1.236AlaHis: 1.236 ± 0.815
9.271AlaIle: 9.271 ± 0.396
1.854AlaLys: 1.854 ± 0.405
8.653AlaLeu: 8.653 ± 0.803
0.618AlaMet: 0.618 ± 0.408
3.09AlaAsn: 3.09 ± 0.403
1.854AlaPro: 1.854 ± 0.409
2.472AlaGln: 2.472 ± 1.625
9.889AlaArg: 9.889 ± 0.826
4.326AlaSer: 4.326 ± 0.412
4.326AlaThr: 4.326 ± 1.215
7.417AlaVal: 7.417 ± 0.805
2.472AlaTrp: 2.472 ± 0.811
3.09AlaTyr: 3.09 ± 2.038
0.0AlaXaa: 0.0 ± 0.0
Cys
1.236CysAla: 1.236 ± 0.002
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.236CysGlu: 1.236 ± 0.815
0.618CysPhe: 0.618 ± 0.408
0.618CysGly: 0.618 ± 0.406
1.236CysHis: 1.236 ± 0.002
0.0CysIle: 0.0 ± 0.0
1.236CysLys: 1.236 ± 0.002
1.854CysLeu: 1.854 ± 1.218
0.0CysMet: 0.0 ± 0.0
0.618CysAsn: 0.618 ± 0.406
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.236CysArg: 1.236 ± 0.815
0.618CysSer: 0.618 ± 0.406
0.618CysThr: 0.618 ± 0.406
1.236CysVal: 1.236 ± 0.812
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.708AspAla: 3.708 ± 0.005
0.618AspCys: 0.618 ± 0.406
1.854AspAsp: 1.854 ± 0.405
3.09AspGlu: 3.09 ± 0.411
4.326AspPhe: 4.326 ± 0.412
3.09AspGly: 3.09 ± 0.403
3.09AspHis: 3.09 ± 1.224
2.472AspIle: 2.472 ± 0.003
1.854AspLys: 1.854 ± 0.409
4.326AspLeu: 4.326 ± 1.215
0.618AspMet: 0.618 ± 0.408
3.708AspAsn: 3.708 ± 1.623
1.236AspPro: 1.236 ± 0.815
1.236AspGln: 1.236 ± 0.002
1.854AspArg: 1.854 ± 0.409
3.09AspSer: 3.09 ± 0.403
3.09AspThr: 3.09 ± 0.403
6.799AspVal: 6.799 ± 2.043
1.854AspTrp: 1.854 ± 1.223
1.236AspTyr: 1.236 ± 0.812
0.0AspXaa: 0.0 ± 0.0
Glu
5.562GluAla: 5.562 ± 1.214
0.618GluCys: 0.618 ± 0.406
2.472GluAsp: 2.472 ± 0.003
6.18GluGlu: 6.18 ± 0.008
3.708GluPhe: 3.708 ± 0.005
2.472GluGly: 2.472 ± 0.811
3.708GluHis: 3.708 ± 0.005
0.618GluIle: 0.618 ± 0.406
3.09GluLys: 3.09 ± 0.411
4.326GluLeu: 4.326 ± 0.412
2.472GluMet: 2.472 ± 1.439
0.618GluAsn: 0.618 ± 0.406
1.854GluPro: 1.854 ± 1.218
1.854GluGln: 1.854 ± 1.223
6.18GluArg: 6.18 ± 1.635
4.944GluSer: 4.944 ± 1.634
3.708GluThr: 3.708 ± 1.623
4.944GluVal: 4.944 ± 1.634
2.472GluTrp: 2.472 ± 0.003
3.09GluTyr: 3.09 ± 0.411
0.0GluXaa: 0.0 ± 0.0
Phe
4.326PheAla: 4.326 ± 0.402
1.236PheCys: 1.236 ± 0.002
1.854PheAsp: 1.854 ± 1.223
3.09PheGlu: 3.09 ± 0.411
0.618PhePhe: 0.618 ± 0.408
2.472PheGly: 2.472 ± 0.811
0.618PheHis: 0.618 ± 0.408
0.618PheIle: 0.618 ± 0.408
3.708PheLys: 3.708 ± 0.818
1.236PheLeu: 1.236 ± 0.002
1.854PheMet: 1.854 ± 0.307
1.236PheAsn: 1.236 ± 0.815
1.854PhePro: 1.854 ± 1.223
1.236PheGln: 1.236 ± 0.002
2.472PheArg: 2.472 ± 0.811
3.708PheSer: 3.708 ± 0.005
1.236PheThr: 1.236 ± 0.002
3.09PheVal: 3.09 ± 1.217
0.0PheTrp: 0.0 ± 0.0
1.236PheTyr: 1.236 ± 0.815
0.0PheXaa: 0.0 ± 0.0
Gly
5.562GlyAla: 5.562 ± 0.414
1.854GlyCys: 1.854 ± 0.409
4.944GlyAsp: 4.944 ± 0.006
4.944GlyGlu: 4.944 ± 1.622
1.854GlyPhe: 1.854 ± 0.409
2.472GlyGly: 2.472 ± 0.817
1.236GlyHis: 1.236 ± 0.812
3.708GlyIle: 3.708 ± 0.818
3.09GlyLys: 3.09 ± 1.217
6.799GlyLeu: 6.799 ± 2.026
0.618GlyMet: 0.618 ± 0.408
1.236GlyAsn: 1.236 ± 0.002
2.472GlyPro: 2.472 ± 0.817
1.236GlyGln: 1.236 ± 0.815
3.09GlyArg: 3.09 ± 0.411
4.944GlySer: 4.944 ± 0.808
5.562GlyThr: 5.562 ± 0.414
6.799GlyVal: 6.799 ± 0.415
0.0GlyTrp: 0.0 ± 0.0
2.472GlyTyr: 2.472 ± 0.811
0.0GlyXaa: 0.0 ± 0.0
His
0.618HisAla: 0.618 ± 0.408
0.0HisCys: 0.0 ± 0.0
1.854HisAsp: 1.854 ± 0.405
0.618HisGlu: 0.618 ± 0.406
0.618HisPhe: 0.618 ± 0.408
0.618HisGly: 0.618 ± 0.408
0.618HisHis: 0.618 ± 0.406
1.236HisIle: 1.236 ± 0.812
0.618HisLys: 0.618 ± 0.408
2.472HisLeu: 2.472 ± 0.817
0.618HisMet: 0.618 ± 0.408
1.854HisAsn: 1.854 ± 0.409
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.618HisArg: 0.618 ± 0.406
3.708HisSer: 3.708 ± 0.818
0.618HisThr: 0.618 ± 0.406
3.708HisVal: 3.708 ± 0.818
1.236HisTrp: 1.236 ± 0.002
1.236HisTyr: 1.236 ± 0.812
0.0HisXaa: 0.0 ± 0.0
Ile
3.708IleAla: 3.708 ± 0.809
0.0IleCys: 0.0 ± 0.0
3.708IleAsp: 3.708 ± 0.809
3.09IleGlu: 3.09 ± 1.224
0.0IlePhe: 0.0 ± 0.0
4.944IleGly: 4.944 ± 0.006
0.618IleHis: 0.618 ± 0.406
1.236IleIle: 1.236 ± 0.002
0.0IleLys: 0.0 ± 0.0
3.09IleLeu: 3.09 ± 0.411
0.618IleMet: 0.618 ± 0.408
3.09IleAsn: 3.09 ± 1.217
5.562IlePro: 5.562 ± 0.4
0.618IleGln: 0.618 ± 0.408
1.854IleArg: 1.854 ± 0.405
3.09IleSer: 3.09 ± 0.411
1.854IleThr: 1.854 ± 0.409
1.236IleVal: 1.236 ± 0.002
0.0IleTrp: 0.0 ± 0.0
3.708IleTyr: 3.708 ± 0.005
0.0IleXaa: 0.0 ± 0.0
Lys
5.562LysAla: 5.562 ± 2.855
1.854LysCys: 1.854 ± 0.409
0.618LysAsp: 0.618 ± 0.408
3.09LysGlu: 3.09 ± 0.403
1.236LysPhe: 1.236 ± 0.815
1.854LysGly: 1.854 ± 0.409
0.0LysHis: 0.0 ± 0.0
3.708LysIle: 3.708 ± 1.623
1.236LysLys: 1.236 ± 0.002
6.18LysLeu: 6.18 ± 1.62
1.854LysMet: 1.854 ± 1.218
1.236LysAsn: 1.236 ± 0.002
0.618LysPro: 0.618 ± 0.406
0.618LysGln: 0.618 ± 0.408
3.708LysArg: 3.708 ± 0.818
1.854LysSer: 1.854 ± 0.409
1.236LysThr: 1.236 ± 0.815
1.854LysVal: 1.854 ± 0.405
0.0LysTrp: 0.0 ± 0.0
1.854LysTyr: 1.854 ± 1.223
0.0LysXaa: 0.0 ± 0.0
Leu
10.507LeuAla: 10.507 ± 0.42
0.618LeuCys: 0.618 ± 0.406
3.09LeuAsp: 3.09 ± 0.403
6.18LeuGlu: 6.18 ± 0.821
3.09LeuPhe: 3.09 ± 1.224
4.944LeuGly: 4.944 ± 0.808
1.854LeuHis: 1.854 ± 0.409
1.236LeuIle: 1.236 ± 0.002
4.326LeuLys: 4.326 ± 2.04
8.653LeuLeu: 8.653 ± 1.638
2.472LeuMet: 2.472 ± 0.817
3.09LeuAsn: 3.09 ± 0.403
3.708LeuPro: 3.708 ± 1.623
1.236LeuGln: 1.236 ± 0.002
9.889LeuArg: 9.889 ± 0.012
8.653LeuSer: 8.653 ± 0.011
4.944LeuThr: 4.944 ± 0.808
9.271LeuVal: 9.271 ± 2.837
2.472LeuTrp: 2.472 ± 0.817
2.472LeuTyr: 2.472 ± 0.817
0.0LeuXaa: 0.0 ± 0.0
Met
1.854MetAla: 1.854 ± 0.409
0.0MetCys: 0.0 ± 0.0
1.236MetAsp: 1.236 ± 0.002
0.618MetGlu: 0.618 ± 0.406
0.0MetPhe: 0.0 ± 0.0
0.618MetGly: 0.618 ± 0.408
0.0MetHis: 0.0 ± 0.0
0.618MetIle: 0.618 ± 0.408
0.618MetLys: 0.618 ± 0.408
2.472MetLeu: 2.472 ± 0.003
0.0MetMet: 0.0 ± 0.0
2.472MetAsn: 2.472 ± 0.811
0.618MetPro: 0.618 ± 0.408
1.854MetGln: 1.854 ± 1.218
4.326MetArg: 4.326 ± 0.402
3.708MetSer: 3.708 ± 0.818
1.236MetThr: 1.236 ± 0.002
0.618MetVal: 0.618 ± 0.406
0.618MetTrp: 0.618 ± 0.408
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.09AsnAla: 3.09 ± 1.217
0.618AsnCys: 0.618 ± 0.406
1.236AsnAsp: 1.236 ± 0.002
1.854AsnGlu: 1.854 ± 1.218
1.236AsnPhe: 1.236 ± 0.002
3.09AsnGly: 3.09 ± 0.403
0.618AsnHis: 0.618 ± 0.406
1.236AsnIle: 1.236 ± 0.815
1.854AsnLys: 1.854 ± 0.405
3.708AsnLeu: 3.708 ± 0.005
2.472AsnMet: 2.472 ± 0.003
2.472AsnAsn: 2.472 ± 0.003
1.854AsnPro: 1.854 ± 1.218
0.618AsnGln: 0.618 ± 0.406
1.854AsnArg: 1.854 ± 1.223
4.326AsnSer: 4.326 ± 0.402
4.326AsnThr: 4.326 ± 0.402
4.944AsnVal: 4.944 ± 1.622
1.236AsnTrp: 1.236 ± 0.812
2.472AsnTyr: 2.472 ± 1.625
0.0AsnXaa: 0.0 ± 0.0
Pro
2.472ProAla: 2.472 ± 0.817
0.0ProCys: 0.0 ± 0.0
2.472ProAsp: 2.472 ± 0.817
1.854ProGlu: 1.854 ± 0.409
1.854ProPhe: 1.854 ± 0.405
1.854ProGly: 1.854 ± 0.405
0.0ProHis: 0.0 ± 0.0
1.854ProIle: 1.854 ± 0.409
1.854ProLys: 1.854 ± 1.218
4.326ProLeu: 4.326 ± 0.412
0.618ProMet: 0.618 ± 0.406
1.236ProAsn: 1.236 ± 0.002
2.472ProPro: 2.472 ± 0.811
1.236ProGln: 1.236 ± 0.812
1.236ProArg: 1.236 ± 0.002
2.472ProSer: 2.472 ± 1.625
3.708ProThr: 3.708 ± 2.446
1.854ProVal: 1.854 ± 0.405
0.618ProTrp: 0.618 ± 0.408
1.236ProTyr: 1.236 ± 0.002
0.0ProXaa: 0.0 ± 0.0
Gln
1.236GlnAla: 1.236 ± 0.812
0.0GlnCys: 0.0 ± 0.0
1.236GlnAsp: 1.236 ± 0.002
1.236GlnGlu: 1.236 ± 0.815
0.0GlnPhe: 0.0 ± 0.0
1.236GlnGly: 1.236 ± 0.812
1.236GlnHis: 1.236 ± 0.002
1.854GlnIle: 1.854 ± 1.218
1.236GlnLys: 1.236 ± 0.812
3.708GlnLeu: 3.708 ± 0.818
0.618GlnMet: 0.618 ± 0.408
0.618GlnAsn: 0.618 ± 0.408
1.236GlnPro: 1.236 ± 0.812
1.854GlnGln: 1.854 ± 1.223
2.472GlnArg: 2.472 ± 0.811
0.618GlnSer: 0.618 ± 0.406
0.618GlnThr: 0.618 ± 0.408
3.09GlnVal: 3.09 ± 1.224
0.0GlnTrp: 0.0 ± 0.0
3.09GlnTyr: 3.09 ± 2.038
0.0GlnXaa: 0.0 ± 0.0
Arg
7.417ArgAla: 7.417 ± 3.264
0.618ArgCys: 0.618 ± 0.406
4.944ArgAsp: 4.944 ± 2.447
3.708ArgGlu: 3.708 ± 0.809
4.944ArgPhe: 4.944 ± 0.006
6.18ArgGly: 6.18 ± 1.635
1.854ArgHis: 1.854 ± 0.409
4.944ArgIle: 4.944 ± 1.634
1.236ArgLys: 1.236 ± 0.815
6.18ArgLeu: 6.18 ± 0.821
1.236ArgMet: 1.236 ± 0.815
3.09ArgAsn: 3.09 ± 1.217
1.236ArgPro: 1.236 ± 0.815
1.236ArgGln: 1.236 ± 0.815
3.09ArgArg: 3.09 ± 0.403
5.562ArgSer: 5.562 ± 2.841
4.326ArgThr: 4.326 ± 2.029
8.035ArgVal: 8.035 ± 1.23
1.236ArgTrp: 1.236 ± 0.002
1.854ArgTyr: 1.854 ± 0.405
0.0ArgXaa: 0.0 ± 0.0
Ser
8.035SerAla: 8.035 ± 2.025
0.0SerCys: 0.0 ± 0.0
2.472SerAsp: 2.472 ± 1.625
6.18SerGlu: 6.18 ± 0.008
0.618SerPhe: 0.618 ± 0.406
6.18SerGly: 6.18 ± 2.434
1.236SerHis: 1.236 ± 0.002
1.854SerIle: 1.854 ± 0.409
3.09SerLys: 3.09 ± 1.224
3.708SerLeu: 3.708 ± 0.818
1.854SerMet: 1.854 ± 0.405
3.09SerAsn: 3.09 ± 0.403
1.236SerPro: 1.236 ± 0.002
4.944SerGln: 4.944 ± 0.006
5.562SerArg: 5.562 ± 2.855
4.944SerSer: 4.944 ± 0.808
3.09SerThr: 3.09 ± 0.403
9.271SerVal: 9.271 ± 1.209
1.236SerTrp: 1.236 ± 0.002
2.472SerTyr: 2.472 ± 0.003
0.0SerXaa: 0.0 ± 0.0
Thr
4.944ThrAla: 4.944 ± 2.435
1.236ThrCys: 1.236 ± 0.002
3.708ThrAsp: 3.708 ± 1.623
3.09ThrGlu: 3.09 ± 0.403
3.708ThrPhe: 3.708 ± 0.818
4.326ThrGly: 4.326 ± 0.412
0.618ThrHis: 0.618 ± 0.406
0.618ThrIle: 0.618 ± 0.408
3.09ThrLys: 3.09 ± 0.411
5.562ThrLeu: 5.562 ± 2.041
1.236ThrMet: 1.236 ± 0.002
1.854ThrAsn: 1.854 ± 0.405
4.326ThrPro: 4.326 ± 1.226
1.854ThrGln: 1.854 ± 0.409
1.854ThrArg: 1.854 ± 1.223
2.472ThrSer: 2.472 ± 0.003
3.09ThrThr: 3.09 ± 1.224
6.799ThrVal: 6.799 ± 1.212
0.618ThrTrp: 0.618 ± 0.406
1.854ThrTyr: 1.854 ± 0.405
0.0ThrXaa: 0.0 ± 0.0
Val
4.944ValAla: 4.944 ± 0.006
1.854ValCys: 1.854 ± 0.405
8.653ValAsp: 8.653 ± 1.638
4.326ValGlu: 4.326 ± 1.215
3.09ValPhe: 3.09 ± 1.217
4.944ValGly: 4.944 ± 2.435
1.854ValHis: 1.854 ± 1.223
2.472ValIle: 2.472 ± 0.811
4.944ValLys: 4.944 ± 0.006
9.889ValLeu: 9.889 ± 0.826
1.236ValMet: 1.236 ± 0.002
8.035ValAsn: 8.035 ± 2.838
2.472ValPro: 2.472 ± 0.003
1.236ValGln: 1.236 ± 0.815
9.271ValArg: 9.271 ± 0.396
4.326ValSer: 4.326 ± 0.402
8.035ValThr: 8.035 ± 2.858
7.417ValVal: 7.417 ± 1.619
0.618ValTrp: 0.618 ± 0.406
3.09ValTyr: 3.09 ± 0.403
0.0ValXaa: 0.0 ± 0.0
Trp
2.472TrpAla: 2.472 ± 0.817
0.0TrpCys: 0.0 ± 0.0
0.618TrpAsp: 0.618 ± 0.408
0.618TrpGlu: 0.618 ± 0.408
1.236TrpPhe: 1.236 ± 0.002
1.236TrpGly: 1.236 ± 0.002
1.236TrpHis: 1.236 ± 0.812
0.0TrpIle: 0.0 ± 0.0
0.618TrpLys: 0.618 ± 0.406
4.326TrpLeu: 4.326 ± 0.402
0.618TrpMet: 0.618 ± 0.408
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.618TrpGln: 0.618 ± 0.406
0.618TrpArg: 0.618 ± 0.408
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.472TrpVal: 2.472 ± 0.003
0.618TrpTrp: 0.618 ± 0.406
1.236TrpTyr: 1.236 ± 0.812
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.09TyrAla: 3.09 ± 0.411
0.0TyrCys: 0.0 ± 0.0
4.326TyrAsp: 4.326 ± 0.402
4.326TyrGlu: 4.326 ± 0.412
0.618TyrPhe: 0.618 ± 0.408
5.562TyrGly: 5.562 ± 2.855
0.0TyrHis: 0.0 ± 0.0
2.472TyrIle: 2.472 ± 0.811
0.618TyrLys: 0.618 ± 0.408
1.236TyrLeu: 1.236 ± 0.002
1.236TyrMet: 1.236 ± 0.812
2.472TyrAsn: 2.472 ± 0.003
0.618TyrPro: 0.618 ± 0.408
1.236TyrGln: 1.236 ± 0.002
1.854TyrArg: 1.854 ± 0.405
3.708TyrSer: 3.708 ± 0.809
1.236TyrThr: 1.236 ± 0.002
1.854TyrVal: 1.854 ± 0.409
1.236TyrTrp: 1.236 ± 0.812
0.618TyrTyr: 0.618 ± 0.406
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski