Amino acid dipepetide frequency for Rhizobium gallicum bv. gallicum R602

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.636AlaAla: 15.636 ± 0.122	1.021AlaCys: 1.021 ± 0.025	6.524AlaAsp: 6.524 ± 0.063	7.246AlaGlu: 7.246 ± 0.074	4.58AlaPhe: 4.58 ± 0.046	9.827AlaGly: 9.827 ± 0.073	2.076AlaHis: 2.076 ± 0.03	7.061AlaIle: 7.061 ± 0.064	4.486AlaLys: 4.486 ± 0.054	12.197AlaLeu: 12.197 ± 0.096	3.427AlaMet: 3.427 ± 0.041	3.047AlaAsn: 3.047 ± 0.043	4.593AlaPro: 4.593 ± 0.057	3.475AlaGln: 3.475 ± 0.043	7.494AlaArg: 7.494 ± 0.074	6.659AlaSer: 6.659 ± 0.056	5.662AlaThr: 5.662 ± 0.052	8.553AlaVal: 8.553 ± 0.073	1.311AlaTrp: 1.311 ± 0.029	2.591AlaTyr: 2.591 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.936CysAla: 0.936 ± 0.023	0.129CysCys: 0.129 ± 0.009	0.54CysAsp: 0.54 ± 0.015	0.476CysGlu: 0.476 ± 0.015	0.371CysPhe: 0.371 ± 0.012	0.97CysGly: 0.97 ± 0.022	0.266CysHis: 0.266 ± 0.011	0.44CysIle: 0.44 ± 0.015	0.218CysLys: 0.218 ± 0.012	0.89CysLeu: 0.89 ± 0.021	0.178CysMet: 0.178 ± 0.009	0.222CysAsn: 0.222 ± 0.01	0.403CysPro: 0.403 ± 0.014	0.243CysGln: 0.243 ± 0.011	0.647CysArg: 0.647 ± 0.019	0.536CysSer: 0.536 ± 0.016	0.393CysThr: 0.393 ± 0.015	0.614CysVal: 0.614 ± 0.017	0.126CysTrp: 0.126 ± 0.008	0.213CysTyr: 0.213 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.22AspAla: 6.22 ± 0.064	0.519AspCys: 0.519 ± 0.017	3.022AspAsp: 3.022 ± 0.047	3.51AspGlu: 3.51 ± 0.045	2.332AspPhe: 2.332 ± 0.041	4.942AspGly: 4.942 ± 0.051	1.234AspHis: 1.234 ± 0.025	3.387AspIle: 3.387 ± 0.037	1.904AspLys: 1.904 ± 0.033	5.644AspLeu: 5.644 ± 0.051	1.369AspMet: 1.369 ± 0.026	1.449AspAsn: 1.449 ± 0.027	3.241AspPro: 3.241 ± 0.045	1.749AspGln: 1.749 ± 0.027	4.082AspArg: 4.082 ± 0.047	2.144AspSer: 2.144 ± 0.032	2.456AspThr: 2.456 ± 0.038	4.124AspVal: 4.124 ± 0.041	0.907AspTrp: 0.907 ± 0.021	1.516AspTyr: 1.516 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	7.188GluAla: 7.188 ± 0.076	0.389GluCys: 0.389 ± 0.014	2.74GluAsp: 2.74 ± 0.041	3.453GluGlu: 3.453 ± 0.047	1.978GluPhe: 1.978 ± 0.031	4.154GluGly: 4.154 ± 0.047	1.219GluHis: 1.219 ± 0.027	3.851GluIle: 3.851 ± 0.05	2.771GluLys: 2.771 ± 0.039	5.529GluLeu: 5.529 ± 0.053	1.597GluMet: 1.597 ± 0.024	1.968GluAsn: 1.968 ± 0.034	2.642GluPro: 2.642 ± 0.044	2.027GluGln: 2.027 ± 0.034	4.791GluArg: 4.791 ± 0.061	2.473GluSer: 2.473 ± 0.035	3.591GluThr: 3.591 ± 0.045	3.725GluVal: 3.725 ± 0.052	0.724GluTrp: 0.724 ± 0.018	1.08GluTyr: 1.08 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	4.709PheAla: 4.709 ± 0.053	0.449PheCys: 0.449 ± 0.014	2.803PheAsp: 2.803 ± 0.041	2.296PheGlu: 2.296 ± 0.034	1.703PhePhe: 1.703 ± 0.035	3.738PheGly: 3.738 ± 0.046	0.798PheHis: 0.798 ± 0.021	1.976PheIle: 1.976 ± 0.031	1.233PheLys: 1.233 ± 0.024	3.608PheLeu: 3.608 ± 0.051	0.85PheMet: 0.85 ± 0.02	1.21PheAsn: 1.21 ± 0.027	1.69PhePro: 1.69 ± 0.028	1.088PheGln: 1.088 ± 0.024	2.385PheArg: 2.385 ± 0.038	2.515PheSer: 2.515 ± 0.035	1.98PheThr: 1.98 ± 0.033	3.056PheVal: 3.056 ± 0.042	0.58PheTrp: 0.58 ± 0.019	1.035PheTyr: 1.035 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	8.286GlyAla: 8.286 ± 0.069	0.84GlyCys: 0.84 ± 0.02	4.138GlyAsp: 4.138 ± 0.053	4.72GlyGlu: 4.72 ± 0.051	3.596GlyPhe: 3.596 ± 0.045	6.648GlyGly: 6.648 ± 0.067	1.861GlyHis: 1.861 ± 0.033	5.091GlyIle: 5.091 ± 0.05	3.766GlyLys: 3.766 ± 0.048	8.335GlyLeu: 8.335 ± 0.074	2.235GlyMet: 2.235 ± 0.033	2.403GlyAsn: 2.403 ± 0.043	3.108GlyPro: 3.108 ± 0.037	2.624GlyGln: 2.624 ± 0.033	5.71GlyArg: 5.71 ± 0.065	4.863GlySer: 4.863 ± 0.05	4.383GlyThr: 4.383 ± 0.052	5.733GlyVal: 5.733 ± 0.055	1.241GlyTrp: 1.241 ± 0.029	2.334GlyTyr: 2.334 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.156HisAla: 2.156 ± 0.038	0.237HisCys: 0.237 ± 0.011	1.226HisAsp: 1.226 ± 0.027	1.132HisGlu: 1.132 ± 0.025	0.949HisPhe: 0.949 ± 0.02	1.875HisGly: 1.875 ± 0.03	0.568HisHis: 0.568 ± 0.02	1.048HisIle: 1.048 ± 0.021	0.521HisLys: 0.521 ± 0.016	2.085HisLeu: 2.085 ± 0.03	0.554HisMet: 0.554 ± 0.015	0.479HisAsn: 0.479 ± 0.017	1.32HisPro: 1.32 ± 0.025	0.647HisGln: 0.647 ± 0.019	1.452HisArg: 1.452 ± 0.03	1.067HisSer: 1.067 ± 0.022	0.818HisThr: 0.818 ± 0.02	1.523HisVal: 1.523 ± 0.031	0.305HisTrp: 0.305 ± 0.012	0.566HisTyr: 0.566 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.941IleAla: 7.941 ± 0.068	0.602IleCys: 0.602 ± 0.018	3.9IleAsp: 3.9 ± 0.047	3.796IleGlu: 3.796 ± 0.044	2.146IlePhe: 2.146 ± 0.034	5.386IleGly: 5.386 ± 0.057	1.031IleHis: 1.031 ± 0.022	2.905IleIle: 2.905 ± 0.041	1.749IleLys: 1.749 ± 0.026	4.964IleLeu: 4.964 ± 0.054	1.17IleMet: 1.17 ± 0.019	1.652IleAsn: 1.652 ± 0.032	2.573IlePro: 2.573 ± 0.037	1.355IleGln: 1.355 ± 0.027	3.581IleArg: 3.581 ± 0.038	3.591IleSer: 3.591 ± 0.049	2.78IleThr: 2.78 ± 0.041	4.691IleVal: 4.691 ± 0.058	0.674IleTrp: 0.674 ± 0.02	1.305IleTyr: 1.305 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.772LysAla: 4.772 ± 0.05	0.191LysCys: 0.191 ± 0.009	2.063LysAsp: 2.063 ± 0.035	2.03LysGlu: 2.03 ± 0.03	1.076LysPhe: 1.076 ± 0.026	2.906LysGly: 2.906 ± 0.043	0.715LysHis: 0.715 ± 0.017	2.224LysIle: 2.224 ± 0.037	1.585LysLys: 1.585 ± 0.036	3.657LysLeu: 3.657 ± 0.046	0.968LysMet: 0.968 ± 0.02	1.153LysAsn: 1.153 ± 0.026	2.263LysPro: 2.263 ± 0.033	1.187LysGln: 1.187 ± 0.024	2.632LysArg: 2.632 ± 0.038	2.322LysSer: 2.322 ± 0.034	2.288LysThr: 2.288 ± 0.033	2.752LysVal: 2.752 ± 0.043	0.407LysTrp: 0.407 ± 0.014	0.736LysTyr: 0.736 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	12.305LeuAla: 12.305 ± 0.08	0.966LeuCys: 0.966 ± 0.023	5.692LeuAsp: 5.692 ± 0.064	5.305LeuGlu: 5.305 ± 0.056	3.82LeuPhe: 3.82 ± 0.047	7.76LeuGly: 7.76 ± 0.08	1.838LeuHis: 1.838 ± 0.033	5.34LeuIle: 5.34 ± 0.055	4.178LeuLys: 4.178 ± 0.047	9.376LeuLeu: 9.376 ± 0.101	2.438LeuMet: 2.438 ± 0.037	2.817LeuAsn: 2.817 ± 0.035	5.29LeuPro: 5.29 ± 0.048	2.986LeuGln: 2.986 ± 0.035	6.242LeuArg: 6.242 ± 0.065	6.98LeuSer: 6.98 ± 0.062	5.481LeuThr: 5.481 ± 0.046	7.205LeuVal: 7.205 ± 0.072	1.081LeuTrp: 1.081 ± 0.024	2.108LeuTyr: 2.108 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.047MetAla: 3.047 ± 0.037	0.159MetCys: 0.159 ± 0.009	1.175MetAsp: 1.175 ± 0.025	1.236MetGlu: 1.236 ± 0.025	0.759MetPhe: 0.759 ± 0.018	1.712MetGly: 1.712 ± 0.03	0.464MetHis: 0.464 ± 0.016	1.553MetIle: 1.553 ± 0.031	1.2MetLys: 1.2 ± 0.026	2.549MetLeu: 2.549 ± 0.04	0.674MetMet: 0.674 ± 0.022	0.88MetAsn: 0.88 ± 0.02	1.542MetPro: 1.542 ± 0.028	0.887MetGln: 0.887 ± 0.021	1.834MetArg: 1.834 ± 0.033	1.793MetSer: 1.793 ± 0.03	1.976MetThr: 1.976 ± 0.029	1.709MetVal: 1.709 ± 0.029	0.214MetTrp: 0.214 ± 0.012	0.333MetTyr: 0.333 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.335AsnAla: 3.335 ± 0.038	0.255AsnCys: 0.255 ± 0.012	1.553AsnAsp: 1.553 ± 0.029	1.491AsnGlu: 1.491 ± 0.031	1.145AsnPhe: 1.145 ± 0.023	2.63AsnGly: 2.63 ± 0.037	0.586AsnHis: 0.586 ± 0.015	1.627AsnIle: 1.627 ± 0.028	0.837AsnLys: 0.837 ± 0.022	2.919AsnLeu: 2.919 ± 0.033	0.72AsnMet: 0.72 ± 0.019	0.867AsnAsn: 0.867 ± 0.02	1.852AsnPro: 1.852 ± 0.031	0.867AsnGln: 0.867 ± 0.019	1.937AsnArg: 1.937 ± 0.032	1.567AsnSer: 1.567 ± 0.029	1.35AsnThr: 1.35 ± 0.028	2.154AsnVal: 2.154 ± 0.037	0.461AsnTrp: 0.461 ± 0.015	0.756AsnTyr: 0.756 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.529ProAla: 5.529 ± 0.066	0.318ProCys: 0.318 ± 0.014	3.308ProAsp: 3.308 ± 0.042	3.436ProGlu: 3.436 ± 0.044	2.059ProPhe: 2.059 ± 0.03	3.991ProGly: 3.991 ± 0.048	1.091ProHis: 1.091 ± 0.022	2.437ProIle: 2.437 ± 0.035	1.825ProLys: 1.825 ± 0.035	4.631ProLeu: 4.631 ± 0.048	1.165ProMet: 1.165 ± 0.021	1.412ProAsn: 1.412 ± 0.025	2.205ProPro: 2.205 ± 0.046	1.695ProGln: 1.695 ± 0.029	2.613ProArg: 2.613 ± 0.037	2.974ProSer: 2.974 ± 0.04	2.3ProThr: 2.3 ± 0.036	4.042ProVal: 4.042 ± 0.055	0.638ProTrp: 0.638 ± 0.016	1.194ProTyr: 1.194 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.807GlnAla: 3.807 ± 0.041	0.223GlnCys: 0.223 ± 0.011	1.411GlnAsp: 1.411 ± 0.027	1.626GlnGlu: 1.626 ± 0.032	1.117GlnPhe: 1.117 ± 0.021	2.139GlnGly: 2.139 ± 0.032	0.61GlnHis: 0.61 ± 0.017	1.928GlnIle: 1.928 ± 0.033	1.311GlnLys: 1.311 ± 0.023	2.952GlnLeu: 2.952 ± 0.044	0.962GlnMet: 0.962 ± 0.024	0.969GlnAsn: 0.969 ± 0.022	1.709GlnPro: 1.709 ± 0.031	1.302GlnGln: 1.302 ± 0.031	2.309GlnArg: 2.309 ± 0.036	1.98GlnSer: 1.98 ± 0.034	1.733GlnThr: 1.733 ± 0.033	2.078GlnVal: 2.078 ± 0.032	0.4GlnTrp: 0.4 ± 0.016	0.642GlnTyr: 0.642 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	6.811ArgAla: 6.811 ± 0.055	0.512ArgCys: 0.512 ± 0.015	3.743ArgAsp: 3.743 ± 0.047	3.946ArgGlu: 3.946 ± 0.052	2.907ArgPhe: 2.907 ± 0.038	4.334ArgGly: 4.334 ± 0.051	1.691ArgHis: 1.691 ± 0.033	4.091ArgIle: 4.091 ± 0.043	2.693ArgLys: 2.693 ± 0.032	7.348ArgLeu: 7.348 ± 0.072	1.897ArgMet: 1.897 ± 0.032	2.136ArgAsn: 2.136 ± 0.03	3.273ArgPro: 3.273 ± 0.041	2.62ArgGln: 2.62 ± 0.036	5.285ArgArg: 5.285 ± 0.058	4.054ArgSer: 4.054 ± 0.055	3.218ArgThr: 3.218 ± 0.043	4.278ArgVal: 4.278 ± 0.05	0.909ArgTrp: 0.909 ± 0.023	1.774ArgTyr: 1.774 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.453SerAla: 6.453 ± 0.058	0.488SerCys: 0.488 ± 0.015	3.204SerAsp: 3.204 ± 0.038	3.143SerGlu: 3.143 ± 0.044	2.562SerPhe: 2.562 ± 0.04	5.822SerGly: 5.822 ± 0.065	1.233SerHis: 1.233 ± 0.024	3.422SerIle: 3.422 ± 0.044	2.013SerLys: 2.013 ± 0.032	5.926SerLeu: 5.926 ± 0.064	1.509SerMet: 1.509 ± 0.028	1.659SerAsn: 1.659 ± 0.029	2.881SerPro: 2.881 ± 0.038	1.765SerGln: 1.765 ± 0.029	3.964SerArg: 3.964 ± 0.048	3.652SerSer: 3.652 ± 0.053	2.93SerThr: 2.93 ± 0.037	4.326SerVal: 4.326 ± 0.053	0.83SerTrp: 0.83 ± 0.022	1.441SerTyr: 1.441 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	6.095ThrAla: 6.095 ± 0.049	0.455ThrCys: 0.455 ± 0.015	2.731ThrAsp: 2.731 ± 0.034	2.738ThrGlu: 2.738 ± 0.037	2.07ThrPhe: 2.07 ± 0.034	4.775ThrGly: 4.775 ± 0.05	1.034ThrHis: 1.034 ± 0.022	3.303ThrIle: 3.303 ± 0.039	1.763ThrLys: 1.763 ± 0.031	5.448ThrLeu: 5.448 ± 0.059	1.272ThrMet: 1.272 ± 0.027	1.396ThrAsn: 1.396 ± 0.028	2.863ThrPro: 2.863 ± 0.04	1.383ThrGln: 1.383 ± 0.028	3.037ThrArg: 3.037 ± 0.036	3.032ThrSer: 3.032 ± 0.044	2.777ThrThr: 2.777 ± 0.045	4.292ThrVal: 4.292 ± 0.051	0.609ThrTrp: 0.609 ± 0.019	1.257ThrTyr: 1.257 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	8.648ValAla: 8.648 ± 0.079	0.668ValCys: 0.668 ± 0.019	3.938ValAsp: 3.938 ± 0.048	4.433ValGlu: 4.433 ± 0.043	2.942ValPhe: 2.942 ± 0.043	5.349ValGly: 5.349 ± 0.055	1.383ValHis: 1.383 ± 0.023	4.351ValIle: 4.351 ± 0.051	2.61ValLys: 2.61 ± 0.043	7.165ValLeu: 7.165 ± 0.059	1.86ValMet: 1.86 ± 0.033	2.063ValAsn: 2.063 ± 0.033	3.581ValPro: 3.581 ± 0.04	2.022ValGln: 2.022 ± 0.032	4.727ValArg: 4.727 ± 0.049	4.822ValSer: 4.822 ± 0.048	4.391ValThr: 4.391 ± 0.052	5.755ValVal: 5.755 ± 0.065	0.845ValTrp: 0.845 ± 0.02	1.512ValTyr: 1.512 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.144TrpAla: 1.144 ± 0.027	0.117TrpCys: 0.117 ± 0.007	0.588TrpAsp: 0.588 ± 0.019	0.568TrpGlu: 0.568 ± 0.016	0.539TrpPhe: 0.539 ± 0.019	0.821TrpGly: 0.821 ± 0.022	0.313TrpHis: 0.313 ± 0.014	0.693TrpIle: 0.693 ± 0.019	0.549TrpLys: 0.549 ± 0.015	1.575TrpLeu: 1.575 ± 0.031	0.367TrpMet: 0.367 ± 0.015	0.505TrpAsn: 0.505 ± 0.018	0.675TrpPro: 0.675 ± 0.02	0.552TrpGln: 0.552 ± 0.017	1.016TrpArg: 1.016 ± 0.022	0.844TrpSer: 0.844 ± 0.02	0.732TrpThr: 0.732 ± 0.024	0.735TrpVal: 0.735 ± 0.021	0.211TrpTrp: 0.211 ± 0.01	0.29TrpTyr: 0.29 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.444TyrAla: 2.444 ± 0.035	0.276TyrCys: 0.276 ± 0.013	1.454TyrAsp: 1.454 ± 0.026	1.309TyrGlu: 1.309 ± 0.024	1.052TyrPhe: 1.052 ± 0.021	2.136TyrGly: 2.136 ± 0.037	0.517TyrHis: 0.517 ± 0.013	1.067TyrIle: 1.067 ± 0.024	0.715TyrLys: 0.715 ± 0.02	2.41TyrLeu: 2.41 ± 0.031	0.482TyrMet: 0.482 ± 0.017	0.621TyrAsn: 0.621 ± 0.018	1.159TyrPro: 1.159 ± 0.022	0.735TyrGln: 0.735 ± 0.018	1.782TyrArg: 1.782 ± 0.031	1.356TyrSer: 1.356 ± 0.03	1.091TyrThr: 1.091 ± 0.025	1.72TyrVal: 1.72 ± 0.029	0.358TyrTrp: 0.358 ± 0.013	0.674TyrTyr: 0.674 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7034 proteins (2066382 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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