Amino acid dipepetide frequency for Rosellinia necatrix megabirnavirus 2-W8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
25.829AlaAla: 25.829 ± 4.394
0.711AlaCys: 0.711 ± 0.353
5.45AlaAsp: 5.45 ± 1.326
4.502AlaGlu: 4.502 ± 1.331
3.791AlaPhe: 3.791 ± 1.403
10.9AlaGly: 10.9 ± 0.974
3.318AlaHis: 3.318 ± 1.045
4.028AlaIle: 4.028 ± 0.456
2.607AlaLys: 2.607 ± 0.103
9.242AlaLeu: 9.242 ± 0.945
4.265AlaMet: 4.265 ± 0.704
5.45AlaAsn: 5.45 ± 1.342
3.791AlaPro: 3.791 ± 0.77
5.924AlaGln: 5.924 ± 0.648
9.242AlaArg: 9.242 ± 2.515
6.872AlaSer: 6.872 ± 1.605
9.005AlaThr: 9.005 ± 1.396
8.531AlaVal: 8.531 ± 2.576
2.133AlaTrp: 2.133 ± 0.602
3.318AlaTyr: 3.318 ± 0.431
0.0AlaXaa: 0.0 ± 0.0
Cys
1.422CysAla: 1.422 ± 0.461
0.0CysCys: 0.0 ± 0.0
0.237CysAsp: 0.237 ± 0.212
0.237CysGlu: 0.237 ± 0.178
0.474CysPhe: 0.474 ± 0.478
1.185CysGly: 1.185 ± 0.394
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.474CysLys: 0.474 ± 0.911
1.422CysLeu: 1.422 ± 0.583
0.237CysMet: 0.237 ± 0.199
1.422CysAsn: 1.422 ± 0.398
0.948CysPro: 0.948 ± 0.207
0.948CysGln: 0.948 ± 0.797
0.711CysArg: 0.711 ± 0.353
0.474CysSer: 0.474 ± 0.398
1.659CysThr: 1.659 ± 0.362
0.948CysVal: 0.948 ± 0.533
0.237CysTrp: 0.237 ± 0.178
0.237CysTyr: 0.237 ± 0.178
0.0CysXaa: 0.0 ± 0.0
Asp
5.924AspAla: 5.924 ± 0.712
0.237AspCys: 0.237 ± 0.212
4.739AspAsp: 4.739 ± 1.057
3.081AspGlu: 3.081 ± 0.643
2.37AspPhe: 2.37 ± 0.982
4.028AspGly: 4.028 ± 0.955
0.711AspHis: 0.711 ± 0.346
1.659AspIle: 1.659 ± 0.287
0.948AspLys: 0.948 ± 0.266
4.739AspLeu: 4.739 ± 0.745
1.422AspMet: 1.422 ± 0.456
1.185AspAsn: 1.185 ± 0.595
3.318AspPro: 3.318 ± 0.544
1.659AspGln: 1.659 ± 0.813
4.739AspArg: 4.739 ± 0.451
3.081AspSer: 3.081 ± 0.806
2.37AspThr: 2.37 ± 0.652
4.502AspVal: 4.502 ± 0.233
0.474AspTrp: 0.474 ± 0.219
2.133AspTyr: 2.133 ± 1.007
0.0AspXaa: 0.0 ± 0.0
Glu
5.924GluAla: 5.924 ± 1.759
0.237GluCys: 0.237 ± 0.212
1.896GluAsp: 1.896 ± 0.581
1.659GluGlu: 1.659 ± 0.497
3.318GluPhe: 3.318 ± 0.96
2.133GluGly: 2.133 ± 0.921
2.133GluHis: 2.133 ± 1.245
1.422GluIle: 1.422 ± 0.395
1.185GluLys: 1.185 ± 0.394
6.635GluLeu: 6.635 ± 1.196
1.659GluMet: 1.659 ± 0.491
1.896GluAsn: 1.896 ± 0.532
1.185GluPro: 1.185 ± 0.674
2.607GluGln: 2.607 ± 0.509
3.318GluArg: 3.318 ± 0.933
2.37GluSer: 2.37 ± 0.796
1.659GluThr: 1.659 ± 0.527
5.213GluVal: 5.213 ± 0.716
1.422GluTrp: 1.422 ± 0.866
1.422GluTyr: 1.422 ± 0.456
0.0GluXaa: 0.0 ± 0.0
Phe
5.213PheAla: 5.213 ± 1.633
0.711PheCys: 0.711 ± 0.387
1.659PheAsp: 1.659 ± 0.527
1.185PheGlu: 1.185 ± 1.06
1.896PhePhe: 1.896 ± 0.806
3.555PheGly: 3.555 ± 0.577
0.237PheHis: 0.237 ± 0.178
0.948PheIle: 0.948 ± 0.446
1.185PheLys: 1.185 ± 0.595
2.844PheLeu: 2.844 ± 0.371
0.0PheMet: 0.0 ± 0.0
2.844PheAsn: 2.844 ± 1.338
1.422PhePro: 1.422 ± 0.322
0.0PheGln: 0.0 ± 0.0
2.37PheArg: 2.37 ± 0.621
1.659PheSer: 1.659 ± 0.864
2.133PheThr: 2.133 ± 0.602
2.133PheVal: 2.133 ± 0.523
0.711PheTrp: 0.711 ± 0.387
1.659PheTyr: 1.659 ± 0.813
0.0PheXaa: 0.0 ± 0.0
Gly
9.005GlyAla: 9.005 ± 1.37
0.948GlyCys: 0.948 ± 0.207
4.739GlyAsp: 4.739 ± 0.795
4.028GlyGlu: 4.028 ± 1.131
2.607GlyPhe: 2.607 ± 0.759
6.398GlyGly: 6.398 ± 1.103
2.133GlyHis: 2.133 ± 0.453
2.133GlyIle: 2.133 ± 0.857
1.422GlyLys: 1.422 ± 0.669
5.687GlyLeu: 5.687 ± 0.633
3.791GlyMet: 3.791 ± 0.593
2.37GlyAsn: 2.37 ± 0.509
3.081GlyPro: 3.081 ± 0.352
4.739GlyGln: 4.739 ± 1.86
5.45GlyArg: 5.45 ± 0.781
4.028GlySer: 4.028 ± 1.214
4.739GlyThr: 4.739 ± 0.969
7.346GlyVal: 7.346 ± 1.06
1.422GlyTrp: 1.422 ± 0.456
2.133GlyTyr: 2.133 ± 0.664
0.0GlyXaa: 0.0 ± 0.0
His
3.318HisAla: 3.318 ± 0.574
0.0HisCys: 0.0 ± 0.0
0.948HisAsp: 0.948 ± 0.266
0.948HisGlu: 0.948 ± 0.438
0.0HisPhe: 0.0 ± 0.0
2.37HisGly: 2.37 ± 0.729
0.474HisHis: 0.474 ± 0.356
1.185HisIle: 1.185 ± 0.452
0.237HisLys: 0.237 ± 0.212
1.422HisLeu: 1.422 ± 0.385
0.474HisMet: 0.474 ± 0.182
1.185HisAsn: 1.185 ± 0.452
1.185HisPro: 1.185 ± 0.76
2.133HisGln: 2.133 ± 0.498
2.133HisArg: 2.133 ± 0.921
1.896HisSer: 1.896 ± 0.629
1.896HisThr: 1.896 ± 0.446
1.422HisVal: 1.422 ± 0.967
0.948HisTrp: 0.948 ± 0.438
0.474HisTyr: 0.474 ± 0.424
0.0HisXaa: 0.0 ± 0.0
Ile
4.028IleAla: 4.028 ± 2.065
0.237IleCys: 0.237 ± 0.212
2.844IleAsp: 2.844 ± 0.481
1.185IleGlu: 1.185 ± 0.535
1.185IlePhe: 1.185 ± 0.52
2.37IleGly: 2.37 ± 0.298
1.185IleHis: 1.185 ± 0.236
0.711IleIle: 0.711 ± 0.636
0.948IleLys: 0.948 ± 0.7
2.607IleLeu: 2.607 ± 0.526
0.474IleMet: 0.474 ± 0.223
1.185IleAsn: 1.185 ± 0.236
2.133IlePro: 2.133 ± 0.389
1.185IleGln: 1.185 ± 0.367
2.607IleArg: 2.607 ± 0.651
1.896IleSer: 1.896 ± 0.591
2.133IleThr: 2.133 ± 0.793
2.844IleVal: 2.844 ± 0.8
1.185IleTrp: 1.185 ± 0.482
0.711IleTyr: 0.711 ± 0.387
0.0IleXaa: 0.0 ± 0.0
Lys
2.133LysAla: 2.133 ± 0.655
0.237LysCys: 0.237 ± 0.178
0.948LysAsp: 0.948 ± 0.446
1.185LysGlu: 1.185 ± 0.903
0.237LysPhe: 0.237 ± 0.212
2.133LysGly: 2.133 ± 0.589
0.474LysHis: 0.474 ± 0.223
0.474LysIle: 0.474 ± 0.398
1.422LysLys: 1.422 ± 0.642
3.081LysLeu: 3.081 ± 0.863
0.711LysMet: 0.711 ± 0.12
0.948LysAsn: 0.948 ± 0.545
0.711LysPro: 0.711 ± 0.636
1.659LysGln: 1.659 ± 0.813
2.607LysArg: 2.607 ± 1.162
0.0LysSer: 0.0 ± 0.0
0.948LysThr: 0.948 ± 0.207
1.422LysVal: 1.422 ± 0.663
0.237LysTrp: 0.237 ± 0.199
0.711LysTyr: 0.711 ± 0.535
0.0LysXaa: 0.0 ± 0.0
Leu
12.559LeuAla: 12.559 ± 0.882
1.185LeuCys: 1.185 ± 0.804
4.028LeuAsp: 4.028 ± 0.704
6.398LeuGlu: 6.398 ± 0.555
2.844LeuPhe: 2.844 ± 0.651
5.213LeuGly: 5.213 ± 0.906
2.133LeuHis: 2.133 ± 0.507
2.607LeuIle: 2.607 ± 0.751
1.896LeuLys: 1.896 ± 0.9
5.213LeuLeu: 5.213 ± 1.743
3.081LeuMet: 3.081 ± 0.586
2.607LeuAsn: 2.607 ± 0.526
3.318LeuPro: 3.318 ± 0.759
4.265LeuGln: 4.265 ± 1.632
10.19LeuArg: 10.19 ± 1.532
5.687LeuSer: 5.687 ± 1.059
4.502LeuThr: 4.502 ± 1.442
7.109LeuVal: 7.109 ± 1.072
1.185LeuTrp: 1.185 ± 0.398
1.422LeuTyr: 1.422 ± 0.758
0.0LeuXaa: 0.0 ± 0.0
Met
4.739MetAla: 4.739 ± 0.906
0.474MetCys: 0.474 ± 0.478
1.896MetAsp: 1.896 ± 0.591
0.711MetGlu: 0.711 ± 0.353
0.474MetPhe: 0.474 ± 0.182
2.844MetGly: 2.844 ± 1.079
0.474MetHis: 0.474 ± 0.424
0.474MetIle: 0.474 ± 0.219
0.948MetLys: 0.948 ± 0.266
3.081MetLeu: 3.081 ± 0.204
0.474MetMet: 0.474 ± 0.223
0.711MetAsn: 0.711 ± 0.636
3.081MetPro: 3.081 ± 0.806
0.948MetGln: 0.948 ± 0.517
4.265MetArg: 4.265 ± 1.045
2.133MetSer: 2.133 ± 0.389
1.422MetThr: 1.422 ± 0.398
1.659MetVal: 1.659 ± 0.362
0.237MetTrp: 0.237 ± 0.199
0.711MetTyr: 0.711 ± 0.366
0.0MetXaa: 0.0 ± 0.0
Asn
4.265AsnAla: 4.265 ± 1.416
0.0AsnCys: 0.0 ± 0.0
2.133AsnAsp: 2.133 ± 0.389
2.37AsnGlu: 2.37 ± 0.483
0.711AsnPhe: 0.711 ± 0.636
3.318AsnGly: 3.318 ± 0.708
0.711AsnHis: 0.711 ± 0.346
1.896AsnIle: 1.896 ± 0.415
0.711AsnLys: 0.711 ± 0.366
3.081AsnLeu: 3.081 ± 0.352
1.659AsnMet: 1.659 ± 0.796
2.37AsnAsn: 2.37 ± 0.708
2.844AsnPro: 2.844 ± 0.477
1.422AsnGln: 1.422 ± 1.341
2.37AsnArg: 2.37 ± 1.516
1.896AsnSer: 1.896 ± 0.834
2.133AsnThr: 2.133 ± 0.872
4.028AsnVal: 4.028 ± 0.921
0.237AsnTrp: 0.237 ± 0.178
0.711AsnTyr: 0.711 ± 0.366
0.0AsnXaa: 0.0 ± 0.0
Pro
6.635ProAla: 6.635 ± 0.775
0.474ProCys: 0.474 ± 0.434
1.896ProAsp: 1.896 ± 0.806
2.37ProGlu: 2.37 ± 0.689
0.474ProPhe: 0.474 ± 0.356
3.791ProGly: 3.791 ± 1.54
2.37ProHis: 2.37 ± 0.471
2.607ProIle: 2.607 ± 0.432
0.948ProLys: 0.948 ± 0.848
5.687ProLeu: 5.687 ± 1.118
0.711ProMet: 0.711 ± 0.12
2.133ProAsn: 2.133 ± 0.664
0.948ProPro: 0.948 ± 0.266
0.474ProGln: 0.474 ± 0.182
1.896ProArg: 1.896 ± 0.537
2.844ProSer: 2.844 ± 0.555
4.028ProThr: 4.028 ± 1.398
3.318ProVal: 3.318 ± 0.591
0.474ProTrp: 0.474 ± 0.219
0.474ProTyr: 0.474 ± 0.223
0.0ProXaa: 0.0 ± 0.0
Gln
3.791GlnAla: 3.791 ± 0.974
0.237GlnCys: 0.237 ± 0.199
1.659GlnAsp: 1.659 ± 0.713
0.948GlnGlu: 0.948 ± 0.845
1.659GlnPhe: 1.659 ± 0.626
3.081GlnGly: 3.081 ± 0.275
1.659GlnHis: 1.659 ± 0.64
1.185GlnIle: 1.185 ± 0.236
0.0GlnLys: 0.0 ± 0.0
4.976GlnLeu: 4.976 ± 2.288
1.659GlnMet: 1.659 ± 0.253
0.711GlnAsn: 0.711 ± 0.583
2.607GlnPro: 2.607 ± 0.408
2.133GlnGln: 2.133 ± 0.742
4.739GlnArg: 4.739 ± 1.357
1.422GlnSer: 1.422 ± 0.774
4.028GlnThr: 4.028 ± 1.214
2.844GlnVal: 2.844 ± 0.798
1.185GlnTrp: 1.185 ± 0.283
1.659GlnTyr: 1.659 ± 0.354
0.237GlnXaa: 0.237 ± 0.455
Arg
6.398ArgAla: 6.398 ± 1.912
2.37ArgCys: 2.37 ± 0.471
3.555ArgAsp: 3.555 ± 0.82
5.687ArgGlu: 5.687 ± 1.767
3.318ArgPhe: 3.318 ± 1.203
4.502ArgGly: 4.502 ± 0.817
0.948ArgHis: 0.948 ± 0.266
2.844ArgIle: 2.844 ± 1.179
0.948ArgLys: 0.948 ± 0.545
6.161ArgLeu: 6.161 ± 0.891
2.844ArgMet: 2.844 ± 1.021
5.213ArgAsn: 5.213 ± 0.913
3.081ArgPro: 3.081 ± 0.716
3.555ArgGln: 3.555 ± 1.113
6.635ArgArg: 6.635 ± 0.749
4.739ArgSer: 4.739 ± 0.857
4.028ArgThr: 4.028 ± 0.955
7.346ArgVal: 7.346 ± 1.411
2.37ArgTrp: 2.37 ± 0.65
2.133ArgTyr: 2.133 ± 0.906
0.0ArgXaa: 0.0 ± 0.0
Ser
6.398SerAla: 6.398 ± 0.978
0.711SerCys: 0.711 ± 0.346
4.265SerAsp: 4.265 ± 0.498
3.081SerGlu: 3.081 ± 0.595
2.607SerPhe: 2.607 ± 0.848
3.791SerGly: 3.791 ± 0.489
0.474SerHis: 0.474 ± 0.219
2.133SerIle: 2.133 ± 0.281
1.185SerLys: 1.185 ± 0.586
5.687SerLeu: 5.687 ± 0.789
1.896SerMet: 1.896 ± 1.181
0.711SerAsn: 0.711 ± 0.12
1.422SerPro: 1.422 ± 0.527
1.422SerGln: 1.422 ± 0.81
3.555SerArg: 3.555 ± 0.746
4.028SerSer: 4.028 ± 2.094
4.502SerThr: 4.502 ± 0.607
4.028SerVal: 4.028 ± 1.737
0.711SerTrp: 0.711 ± 0.366
0.948SerTyr: 0.948 ± 0.446
0.0SerXaa: 0.0 ± 0.0
Thr
6.872ThrAla: 6.872 ± 1.382
1.896ThrCys: 1.896 ± 0.203
2.607ThrAsp: 2.607 ± 0.904
1.896ThrGlu: 1.896 ± 0.385
2.844ThrPhe: 2.844 ± 0.827
6.635ThrGly: 6.635 ± 1.595
1.659ThrHis: 1.659 ± 0.494
4.739ThrIle: 4.739 ± 0.556
1.896ThrLys: 1.896 ± 0.352
5.45ThrLeu: 5.45 ± 0.523
2.844ThrMet: 2.844 ± 0.905
1.185ThrAsn: 1.185 ± 0.625
3.791ThrPro: 3.791 ± 0.649
2.37ThrGln: 2.37 ± 0.729
3.318ThrArg: 3.318 ± 1.467
1.896ThrSer: 1.896 ± 0.649
3.791ThrThr: 3.791 ± 0.7
2.844ThrVal: 2.844 ± 0.644
2.133ThrTrp: 2.133 ± 0.374
1.422ThrTyr: 1.422 ± 0.398
0.0ThrXaa: 0.0 ± 0.0
Val
10.9ValAla: 10.9 ± 1.896
1.185ValCys: 1.185 ± 0.398
4.976ValAsp: 4.976 ± 0.775
5.924ValGlu: 5.924 ± 0.524
1.422ValPhe: 1.422 ± 0.538
6.398ValGly: 6.398 ± 1.65
2.133ValHis: 2.133 ± 0.833
1.422ValIle: 1.422 ± 0.601
2.844ValLys: 2.844 ± 0.481
5.45ValLeu: 5.45 ± 1.32
2.37ValMet: 2.37 ± 0.65
2.844ValAsn: 2.844 ± 0.623
4.502ValPro: 4.502 ± 1.012
3.318ValGln: 3.318 ± 0.759
5.45ValArg: 5.45 ± 1.158
3.791ValSer: 3.791 ± 0.381
4.265ValThr: 4.265 ± 0.992
5.924ValVal: 5.924 ± 0.714
0.948ValTrp: 0.948 ± 0.207
1.659ValTyr: 1.659 ± 0.287
0.0ValXaa: 0.0 ± 0.0
Trp
1.659TrpAla: 1.659 ± 0.491
0.237TrpCys: 0.237 ± 0.199
0.948TrpAsp: 0.948 ± 0.207
0.711TrpGlu: 0.711 ± 0.291
1.422TrpPhe: 1.422 ± 0.322
1.422TrpGly: 1.422 ± 0.706
0.237TrpHis: 0.237 ± 0.178
0.237TrpIle: 0.237 ± 0.199
0.0TrpLys: 0.0 ± 0.0
2.37TrpLeu: 2.37 ± 0.689
0.711TrpMet: 0.711 ± 0.387
0.711TrpAsn: 0.711 ± 0.12
0.711TrpPro: 0.711 ± 0.12
1.422TrpGln: 1.422 ± 1.269
1.422TrpArg: 1.422 ± 0.377
0.948TrpSer: 0.948 ± 0.438
0.948TrpThr: 0.948 ± 0.505
1.896TrpVal: 1.896 ± 0.203
0.711TrpTrp: 0.711 ± 0.12
0.711TrpTyr: 0.711 ± 0.346
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.896TyrAla: 1.896 ± 0.532
1.185TyrCys: 1.185 ± 0.283
1.896TyrAsp: 1.896 ± 0.654
1.185TyrGlu: 1.185 ± 0.394
0.711TyrPhe: 0.711 ± 0.366
2.133TyrGly: 2.133 ± 0.527
1.185TyrHis: 1.185 ± 0.437
0.948TyrIle: 0.948 ± 0.501
0.237TyrLys: 0.237 ± 0.199
2.607TyrLeu: 2.607 ± 1.017
0.237TyrMet: 0.237 ± 0.199
1.422TyrAsn: 1.422 ± 0.398
0.474TyrPro: 0.474 ± 0.219
0.237TyrGln: 0.237 ± 0.212
1.659TyrArg: 1.659 ± 0.545
1.896TyrSer: 1.896 ± 0.892
1.896TyrThr: 1.896 ± 1.414
2.37TyrVal: 2.37 ± 0.363
0.474TyrTrp: 0.474 ± 0.398
0.711TyrTyr: 0.711 ± 0.366
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.237XaaLys: 0.237 ± 0.455
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4221 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski