Amino acid dipepetide frequency for Streptococcus phage O1205 (Streptococcus bacteriophage phi-O1205)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.396AlaAla: 5.396 ± 1.397
0.45AlaCys: 0.45 ± 0.197
4.721AlaAsp: 4.721 ± 0.884
4.421AlaGlu: 4.421 ± 0.625
2.773AlaPhe: 2.773 ± 0.858
5.321AlaGly: 5.321 ± 0.887
0.899AlaHis: 0.899 ± 0.263
5.546AlaIle: 5.546 ± 1.303
5.096AlaLys: 5.096 ± 0.615
5.321AlaLeu: 5.321 ± 0.735
2.323AlaMet: 2.323 ± 0.753
3.522AlaAsn: 3.522 ± 0.633
2.398AlaPro: 2.398 ± 0.397
2.698AlaGln: 2.698 ± 0.609
3.147AlaArg: 3.147 ± 0.525
4.946AlaSer: 4.946 ± 0.92
4.047AlaThr: 4.047 ± 0.672
4.197AlaVal: 4.197 ± 0.768
0.974AlaTrp: 0.974 ± 0.296
2.998AlaTyr: 2.998 ± 0.507
0.0AlaXaa: 0.0 ± 0.0
Cys
0.15CysAla: 0.15 ± 0.106
0.15CysCys: 0.15 ± 0.121
0.525CysAsp: 0.525 ± 0.245
0.674CysGlu: 0.674 ± 0.288
0.075CysPhe: 0.075 ± 0.068
0.525CysGly: 0.525 ± 0.245
0.15CysHis: 0.15 ± 0.099
0.3CysIle: 0.3 ± 0.126
0.674CysLys: 0.674 ± 0.262
0.45CysLeu: 0.45 ± 0.229
0.15CysMet: 0.15 ± 0.108
0.45CysAsn: 0.45 ± 0.222
0.225CysPro: 0.225 ± 0.127
0.225CysGln: 0.225 ± 0.125
0.225CysArg: 0.225 ± 0.12
0.375CysSer: 0.375 ± 0.167
0.45CysThr: 0.45 ± 0.18
0.15CysVal: 0.15 ± 0.114
0.225CysTrp: 0.225 ± 0.157
0.6CysTyr: 0.6 ± 0.287
0.0CysXaa: 0.0 ± 0.0
Asp
2.623AspAla: 2.623 ± 0.541
0.749AspCys: 0.749 ± 0.251
4.347AspAsp: 4.347 ± 0.562
4.272AspGlu: 4.272 ± 0.592
3.147AspPhe: 3.147 ± 0.565
6.595AspGly: 6.595 ± 1.259
0.375AspHis: 0.375 ± 0.146
4.197AspIle: 4.197 ± 0.475
5.246AspLys: 5.246 ± 0.777
4.571AspLeu: 4.571 ± 0.535
1.424AspMet: 1.424 ± 0.347
4.347AspAsn: 4.347 ± 0.612
1.124AspPro: 1.124 ± 0.305
1.724AspGln: 1.724 ± 0.355
2.248AspArg: 2.248 ± 0.346
4.272AspSer: 4.272 ± 0.497
2.998AspThr: 2.998 ± 0.427
3.972AspVal: 3.972 ± 0.515
0.974AspTrp: 0.974 ± 0.335
3.897AspTyr: 3.897 ± 0.56
0.0AspXaa: 0.0 ± 0.0
Glu
4.721GluAla: 4.721 ± 0.662
0.3GluCys: 0.3 ± 0.147
2.848GluAsp: 2.848 ± 0.511
3.747GluGlu: 3.747 ± 0.91
3.372GluPhe: 3.372 ± 0.492
3.672GluGly: 3.672 ± 0.411
1.349GluHis: 1.349 ± 0.336
5.695GluIle: 5.695 ± 0.893
4.571GluLys: 4.571 ± 0.867
6.67GluLeu: 6.67 ± 1.038
2.248GluMet: 2.248 ± 0.401
3.972GluAsn: 3.972 ± 0.549
1.799GluPro: 1.799 ± 0.525
2.773GluGln: 2.773 ± 0.526
3.447GluArg: 3.447 ± 0.624
2.473GluSer: 2.473 ± 0.584
3.222GluThr: 3.222 ± 0.506
4.721GluVal: 4.721 ± 0.711
1.199GluTrp: 1.199 ± 0.291
3.147GluTyr: 3.147 ± 0.694
0.0GluXaa: 0.0 ± 0.0
Phe
2.848PheAla: 2.848 ± 0.426
0.3PheCys: 0.3 ± 0.134
2.623PheAsp: 2.623 ± 0.494
2.998PheGlu: 2.998 ± 0.463
1.349PhePhe: 1.349 ± 0.252
3.672PheGly: 3.672 ± 0.571
0.225PheHis: 0.225 ± 0.127
2.548PheIle: 2.548 ± 0.467
4.272PheLys: 4.272 ± 0.581
2.098PheLeu: 2.098 ± 0.538
0.974PheMet: 0.974 ± 0.284
3.147PheAsn: 3.147 ± 0.442
0.749PhePro: 0.749 ± 0.273
1.049PheGln: 1.049 ± 0.287
1.499PheArg: 1.499 ± 0.312
2.998PheSer: 2.998 ± 0.455
2.248PheThr: 2.248 ± 0.443
1.948PheVal: 1.948 ± 0.309
0.749PheTrp: 0.749 ± 0.258
1.424PheTyr: 1.424 ± 0.338
0.0PheXaa: 0.0 ± 0.0
Gly
4.871GlyAla: 4.871 ± 0.678
0.375GlyCys: 0.375 ± 0.163
3.447GlyAsp: 3.447 ± 0.396
3.372GlyGlu: 3.372 ± 0.537
2.923GlyPhe: 2.923 ± 0.438
4.122GlyGly: 4.122 ± 0.613
1.199GlyHis: 1.199 ± 0.323
6.22GlyIle: 6.22 ± 1.479
6.894GlyLys: 6.894 ± 0.67
5.845GlyLeu: 5.845 ± 0.747
1.649GlyMet: 1.649 ± 0.462
4.122GlyAsn: 4.122 ± 0.619
1.124GlyPro: 1.124 ± 0.425
2.473GlyGln: 2.473 ± 0.41
3.147GlyArg: 3.147 ± 0.635
4.047GlySer: 4.047 ± 0.662
5.546GlyThr: 5.546 ± 0.716
4.946GlyVal: 4.946 ± 0.685
1.274GlyTrp: 1.274 ± 0.232
2.848GlyTyr: 2.848 ± 0.407
0.0GlyXaa: 0.0 ± 0.0
His
0.749HisAla: 0.749 ± 0.206
0.075HisCys: 0.075 ± 0.088
1.124HisAsp: 1.124 ± 0.246
0.824HisGlu: 0.824 ± 0.276
0.45HisPhe: 0.45 ± 0.208
0.749HisGly: 0.749 ± 0.256
0.375HisHis: 0.375 ± 0.132
0.824HisIle: 0.824 ± 0.267
0.674HisLys: 0.674 ± 0.198
0.899HisLeu: 0.899 ± 0.32
0.45HisMet: 0.45 ± 0.193
0.674HisAsn: 0.674 ± 0.265
0.525HisPro: 0.525 ± 0.19
0.3HisGln: 0.3 ± 0.142
0.225HisArg: 0.225 ± 0.113
0.974HisSer: 0.974 ± 0.225
0.45HisThr: 0.45 ± 0.189
1.349HisVal: 1.349 ± 0.273
0.3HisTrp: 0.3 ± 0.149
0.824HisTyr: 0.824 ± 0.295
0.0HisXaa: 0.0 ± 0.0
Ile
5.321IleAla: 5.321 ± 1.016
0.3IleCys: 0.3 ± 0.123
5.77IleAsp: 5.77 ± 0.681
5.021IleGlu: 5.021 ± 0.779
1.724IlePhe: 1.724 ± 0.334
4.571IleGly: 4.571 ± 0.919
0.525IleHis: 0.525 ± 0.15
4.272IleIle: 4.272 ± 0.839
5.246IleLys: 5.246 ± 0.672
3.672IleLeu: 3.672 ± 0.51
1.799IleMet: 1.799 ± 0.339
4.047IleAsn: 4.047 ± 0.593
2.623IlePro: 2.623 ± 0.458
2.698IleGln: 2.698 ± 0.496
2.923IleArg: 2.923 ± 0.57
6.295IleSer: 6.295 ± 1.065
4.646IleThr: 4.646 ± 0.648
3.822IleVal: 3.822 ± 0.567
0.824IleTrp: 0.824 ± 0.242
3.297IleTyr: 3.297 ± 0.663
0.0IleXaa: 0.0 ± 0.0
Lys
5.92LysAla: 5.92 ± 0.699
0.525LysCys: 0.525 ± 0.213
4.646LysAsp: 4.646 ± 0.888
6.745LysGlu: 6.745 ± 0.989
2.623LysPhe: 2.623 ± 0.599
5.621LysGly: 5.621 ± 0.598
1.124LysHis: 1.124 ± 0.31
4.796LysIle: 4.796 ± 0.731
5.621LysLys: 5.621 ± 0.954
5.92LysLeu: 5.92 ± 0.727
1.574LysMet: 1.574 ± 0.443
3.747LysAsn: 3.747 ± 0.726
3.073LysPro: 3.073 ± 0.495
2.323LysGln: 2.323 ± 0.438
4.796LysArg: 4.796 ± 0.669
5.471LysSer: 5.471 ± 0.653
5.77LysThr: 5.77 ± 0.597
5.171LysVal: 5.171 ± 0.743
0.974LysTrp: 0.974 ± 0.235
2.923LysTyr: 2.923 ± 0.454
0.0LysXaa: 0.0 ± 0.0
Leu
5.92LeuAla: 5.92 ± 0.754
0.6LeuCys: 0.6 ± 0.217
4.721LeuAsp: 4.721 ± 0.621
5.321LeuGlu: 5.321 ± 0.911
2.848LeuPhe: 2.848 ± 0.333
5.096LeuGly: 5.096 ± 0.735
0.525LeuHis: 0.525 ± 0.211
3.597LeuIle: 3.597 ± 0.509
5.845LeuLys: 5.845 ± 0.643
5.096LeuLeu: 5.096 ± 0.741
1.799LeuMet: 1.799 ± 0.289
5.321LeuAsn: 5.321 ± 0.532
2.398LeuPro: 2.398 ± 0.393
3.073LeuGln: 3.073 ± 0.394
2.773LeuArg: 2.773 ± 0.473
6.52LeuSer: 6.52 ± 0.731
6.595LeuThr: 6.595 ± 0.968
4.347LeuVal: 4.347 ± 0.611
0.749LeuTrp: 0.749 ± 0.293
2.923LeuTyr: 2.923 ± 0.502
0.0LeuXaa: 0.0 ± 0.0
Met
2.473MetAla: 2.473 ± 0.499
0.075MetCys: 0.075 ± 0.073
0.824MetAsp: 0.824 ± 0.211
0.974MetGlu: 0.974 ± 0.223
0.974MetPhe: 0.974 ± 0.244
1.274MetGly: 1.274 ± 0.387
0.525MetHis: 0.525 ± 0.203
1.499MetIle: 1.499 ± 0.5
2.548MetLys: 2.548 ± 0.422
1.574MetLeu: 1.574 ± 0.301
0.674MetMet: 0.674 ± 0.365
0.824MetAsn: 0.824 ± 0.233
0.525MetPro: 0.525 ± 0.198
1.349MetGln: 1.349 ± 0.501
0.824MetArg: 0.824 ± 0.233
1.649MetSer: 1.649 ± 0.402
2.098MetThr: 2.098 ± 0.48
1.424MetVal: 1.424 ± 0.342
0.15MetTrp: 0.15 ± 0.098
0.45MetTyr: 0.45 ± 0.201
0.0MetXaa: 0.0 ± 0.0
Asn
3.972AsnAla: 3.972 ± 0.583
0.45AsnCys: 0.45 ± 0.154
3.522AsnAsp: 3.522 ± 0.642
4.496AsnGlu: 4.496 ± 0.757
1.874AsnPhe: 1.874 ± 0.375
6.22AsnGly: 6.22 ± 0.934
1.499AsnHis: 1.499 ± 0.342
3.372AsnIle: 3.372 ± 0.354
3.747AsnLys: 3.747 ± 0.627
4.272AsnLeu: 4.272 ± 0.475
1.049AsnMet: 1.049 ± 0.296
3.522AsnAsn: 3.522 ± 0.59
2.023AsnPro: 2.023 ± 0.298
1.574AsnGln: 1.574 ± 0.383
1.874AsnArg: 1.874 ± 0.417
3.222AsnSer: 3.222 ± 0.408
3.747AsnThr: 3.747 ± 0.524
4.197AsnVal: 4.197 ± 0.504
1.274AsnTrp: 1.274 ± 0.312
1.799AsnTyr: 1.799 ± 0.371
0.0AsnXaa: 0.0 ± 0.0
Pro
1.649ProAla: 1.649 ± 0.311
0.075ProCys: 0.075 ± 0.075
2.023ProAsp: 2.023 ± 0.436
1.874ProGlu: 1.874 ± 0.365
1.199ProPhe: 1.199 ± 0.252
1.199ProGly: 1.199 ± 0.313
0.225ProHis: 0.225 ± 0.127
1.724ProIle: 1.724 ± 0.386
2.698ProLys: 2.698 ± 0.533
2.023ProLeu: 2.023 ± 0.367
0.3ProMet: 0.3 ± 0.15
1.649ProAsn: 1.649 ± 0.359
1.274ProPro: 1.274 ± 0.354
1.124ProGln: 1.124 ± 0.298
1.424ProArg: 1.424 ± 0.335
2.473ProSer: 2.473 ± 0.396
1.649ProThr: 1.649 ± 0.434
2.698ProVal: 2.698 ± 0.515
0.225ProTrp: 0.225 ± 0.121
1.124ProTyr: 1.124 ± 0.3
0.0ProXaa: 0.0 ± 0.0
Gln
3.597GlnAla: 3.597 ± 0.664
0.375GlnCys: 0.375 ± 0.167
2.323GlnAsp: 2.323 ± 0.438
2.398GlnGlu: 2.398 ± 0.452
1.499GlnPhe: 1.499 ± 0.359
2.248GlnGly: 2.248 ± 0.618
0.225GlnHis: 0.225 ± 0.117
2.473GlnIle: 2.473 ± 0.546
2.398GlnLys: 2.398 ± 0.377
3.747GlnLeu: 3.747 ± 0.457
0.525GlnMet: 0.525 ± 0.23
1.649GlnAsn: 1.649 ± 0.311
0.974GlnPro: 0.974 ± 0.365
1.199GlnGln: 1.199 ± 0.22
1.424GlnArg: 1.424 ± 0.272
2.773GlnSer: 2.773 ± 0.767
2.623GlnThr: 2.623 ± 0.448
2.473GlnVal: 2.473 ± 0.33
0.45GlnTrp: 0.45 ± 0.162
1.499GlnTyr: 1.499 ± 0.462
0.0GlnXaa: 0.0 ± 0.0
Arg
2.848ArgAla: 2.848 ± 0.439
0.45ArgCys: 0.45 ± 0.186
2.098ArgAsp: 2.098 ± 0.294
2.998ArgGlu: 2.998 ± 0.503
2.023ArgPhe: 2.023 ± 0.361
2.398ArgGly: 2.398 ± 0.358
0.525ArgHis: 0.525 ± 0.212
2.623ArgIle: 2.623 ± 0.551
3.597ArgLys: 3.597 ± 0.682
3.073ArgLeu: 3.073 ± 0.528
1.649ArgMet: 1.649 ± 0.31
2.848ArgAsn: 2.848 ± 0.465
0.824ArgPro: 0.824 ± 0.245
1.724ArgGln: 1.724 ± 0.294
1.499ArgArg: 1.499 ± 0.4
2.023ArgSer: 2.023 ± 0.365
2.173ArgThr: 2.173 ± 0.385
2.923ArgVal: 2.923 ± 0.46
0.674ArgTrp: 0.674 ± 0.249
2.248ArgTyr: 2.248 ± 0.422
0.0ArgXaa: 0.0 ± 0.0
Ser
5.77SerAla: 5.77 ± 1.727
0.45SerCys: 0.45 ± 0.224
4.571SerAsp: 4.571 ± 0.56
4.047SerGlu: 4.047 ± 0.633
2.998SerPhe: 2.998 ± 0.564
4.946SerGly: 4.946 ± 0.724
0.6SerHis: 0.6 ± 0.211
6.145SerIle: 6.145 ± 0.633
4.646SerLys: 4.646 ± 0.553
4.796SerLeu: 4.796 ± 0.71
1.274SerMet: 1.274 ± 0.277
3.297SerAsn: 3.297 ± 0.423
1.874SerPro: 1.874 ± 0.393
2.998SerGln: 2.998 ± 0.658
2.473SerArg: 2.473 ± 0.431
4.871SerSer: 4.871 ± 1.166
4.946SerThr: 4.946 ± 0.6
5.695SerVal: 5.695 ± 0.848
0.6SerTrp: 0.6 ± 0.262
2.248SerTyr: 2.248 ± 0.469
0.0SerXaa: 0.0 ± 0.0
Thr
4.347ThrAla: 4.347 ± 1.082
0.3ThrCys: 0.3 ± 0.257
4.272ThrAsp: 4.272 ± 0.743
2.998ThrGlu: 2.998 ± 0.472
3.897ThrPhe: 3.897 ± 0.444
4.122ThrGly: 4.122 ± 0.632
0.899ThrHis: 0.899 ± 0.245
5.471ThrIle: 5.471 ± 0.905
5.995ThrLys: 5.995 ± 0.653
5.77ThrLeu: 5.77 ± 0.567
0.899ThrMet: 0.899 ± 0.304
3.372ThrAsn: 3.372 ± 0.48
1.874ThrPro: 1.874 ± 0.364
2.848ThrGln: 2.848 ± 0.517
1.724ThrArg: 1.724 ± 0.427
4.496ThrSer: 4.496 ± 1.06
4.272ThrThr: 4.272 ± 0.706
5.096ThrVal: 5.096 ± 0.551
0.6ThrTrp: 0.6 ± 0.232
3.147ThrTyr: 3.147 ± 0.595
0.0ThrXaa: 0.0 ± 0.0
Val
3.522ValAla: 3.522 ± 0.658
0.15ValCys: 0.15 ± 0.11
4.646ValAsp: 4.646 ± 0.528
4.871ValGlu: 4.871 ± 0.875
1.948ValPhe: 1.948 ± 0.337
4.646ValGly: 4.646 ± 0.752
0.749ValHis: 0.749 ± 0.277
4.421ValIle: 4.421 ± 0.456
5.845ValLys: 5.845 ± 0.609
5.77ValLeu: 5.77 ± 0.851
1.274ValMet: 1.274 ± 0.278
4.197ValAsn: 4.197 ± 0.69
1.724ValPro: 1.724 ± 0.398
2.623ValGln: 2.623 ± 0.485
2.248ValArg: 2.248 ± 0.357
5.321ValSer: 5.321 ± 0.655
5.171ValThr: 5.171 ± 0.688
4.871ValVal: 4.871 ± 0.572
1.049ValTrp: 1.049 ± 0.292
1.874ValTyr: 1.874 ± 0.447
0.0ValXaa: 0.0 ± 0.0
Trp
0.749TrpAla: 0.749 ± 0.221
0.225TrpCys: 0.225 ± 0.136
0.899TrpAsp: 0.899 ± 0.305
1.124TrpGlu: 1.124 ± 0.279
0.525TrpPhe: 0.525 ± 0.195
0.899TrpGly: 0.899 ± 0.229
0.45TrpHis: 0.45 ± 0.169
0.674TrpIle: 0.674 ± 0.169
0.674TrpLys: 0.674 ± 0.17
0.899TrpLeu: 0.899 ± 0.311
0.075TrpMet: 0.075 ± 0.079
0.674TrpAsn: 0.674 ± 0.296
0.225TrpPro: 0.225 ± 0.121
0.674TrpGln: 0.674 ± 0.221
0.749TrpArg: 0.749 ± 0.279
1.724TrpSer: 1.724 ± 0.563
1.049TrpThr: 1.049 ± 0.32
0.974TrpVal: 0.974 ± 0.254
0.225TrpTrp: 0.225 ± 0.157
0.45TrpTyr: 0.45 ± 0.153
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.747TyrAla: 3.747 ± 0.597
0.375TyrCys: 0.375 ± 0.144
3.147TyrAsp: 3.147 ± 0.588
2.773TyrGlu: 2.773 ± 0.47
1.499TyrPhe: 1.499 ± 0.355
2.548TyrGly: 2.548 ± 0.448
0.375TyrHis: 0.375 ± 0.178
2.998TyrIle: 2.998 ± 0.453
3.073TyrLys: 3.073 ± 0.516
3.597TyrLeu: 3.597 ± 0.597
0.525TyrMet: 0.525 ± 0.175
2.323TyrAsn: 2.323 ± 0.429
1.274TyrPro: 1.274 ± 0.344
1.499TyrGln: 1.499 ± 0.372
2.548TyrArg: 2.548 ± 0.655
2.323TyrSer: 2.323 ± 0.479
2.698TyrThr: 2.698 ± 0.472
1.948TyrVal: 1.948 ± 0.4
0.45TyrTrp: 0.45 ± 0.168
1.874TyrTyr: 1.874 ± 0.53
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 57 proteins (13345 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski