Amino acid dipepetide frequency for Salmonella phage IKe (Bacteriophage IKe)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.105AlaAla: 7.105 ± 2.119
2.22AlaCys: 2.22 ± 1.291
4.44AlaAsp: 4.44 ± 1.521
2.664AlaGlu: 2.664 ± 0.884
1.332AlaPhe: 1.332 ± 0.728
4.44AlaGly: 4.44 ± 1.726
0.888AlaHis: 0.888 ± 0.463
4.44AlaIle: 4.44 ± 1.772
7.105AlaLys: 7.105 ± 1.752
9.769AlaLeu: 9.769 ± 2.55
1.332AlaMet: 1.332 ± 0.887
3.552AlaAsn: 3.552 ± 1.29
0.444AlaPro: 0.444 ± 0.361
3.552AlaGln: 3.552 ± 1.232
2.22AlaArg: 2.22 ± 0.85
4.885AlaSer: 4.885 ± 1.06
2.22AlaThr: 2.22 ± 1.659
3.996AlaVal: 3.996 ± 0.892
0.888AlaTrp: 0.888 ± 0.718
2.664AlaTyr: 2.664 ± 1.085
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.332CysAsp: 1.332 ± 0.683
1.776CysGlu: 1.776 ± 0.839
0.444CysPhe: 0.444 ± 0.361
1.776CysGly: 1.776 ± 0.91
0.888CysHis: 0.888 ± 0.67
0.444CysIle: 0.444 ± 0.565
0.0CysLys: 0.0 ± 0.0
1.332CysLeu: 1.332 ± 0.45
0.0CysMet: 0.0 ± 0.0
0.444CysAsn: 0.444 ± 0.359
0.444CysPro: 0.444 ± 0.405
0.444CysGln: 0.444 ± 0.359
0.888CysArg: 0.888 ± 0.809
0.444CysSer: 0.444 ± 0.359
0.444CysThr: 0.444 ± 0.359
0.888CysVal: 0.888 ± 0.427
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.773AspAla: 5.773 ± 1.697
0.0AspCys: 0.0 ± 0.0
3.108AspAsp: 3.108 ± 1.138
2.22AspGlu: 2.22 ± 1.177
2.664AspPhe: 2.664 ± 0.721
5.773AspGly: 5.773 ± 1.658
0.444AspHis: 0.444 ± 0.34
4.44AspIle: 4.44 ± 1.207
3.552AspLys: 3.552 ± 1.843
6.661AspLeu: 6.661 ± 1.172
0.888AspMet: 0.888 ± 0.681
5.329AspAsn: 5.329 ± 1.104
0.888AspPro: 0.888 ± 0.723
1.776AspGln: 1.776 ± 0.588
1.332AspArg: 1.332 ± 0.705
5.773AspSer: 5.773 ± 2.349
3.552AspThr: 3.552 ± 1.961
4.885AspVal: 4.885 ± 1.86
0.444AspTrp: 0.444 ± 0.405
2.22AspTyr: 2.22 ± 1.174
0.0AspXaa: 0.0 ± 0.0
Glu
2.664GluAla: 2.664 ± 0.843
0.444GluCys: 0.444 ± 0.405
2.22GluAsp: 2.22 ± 0.663
0.888GluGlu: 0.888 ± 0.718
0.444GluPhe: 0.444 ± 0.34
4.44GluGly: 4.44 ± 1.411
0.444GluHis: 0.444 ± 0.405
2.664GluIle: 2.664 ± 1.066
1.332GluLys: 1.332 ± 0.432
2.22GluLeu: 2.22 ± 1.42
0.444GluMet: 0.444 ± 0.359
0.444GluAsn: 0.444 ± 0.34
2.664GluPro: 2.664 ± 1.014
1.776GluGln: 1.776 ± 1.112
2.664GluArg: 2.664 ± 1.025
5.329GluSer: 5.329 ± 1.684
0.888GluThr: 0.888 ± 0.463
1.776GluVal: 1.776 ± 0.992
0.888GluTrp: 0.888 ± 0.537
0.888GluTyr: 0.888 ± 0.427
0.0GluXaa: 0.0 ± 0.0
Phe
3.108PheAla: 3.108 ± 1.197
0.0PheCys: 0.0 ± 0.0
2.22PheAsp: 2.22 ± 0.861
3.108PheGlu: 3.108 ± 1.761
2.22PhePhe: 2.22 ± 1.179
5.329PheGly: 5.329 ± 1.217
0.0PheHis: 0.0 ± 0.0
1.332PheIle: 1.332 ± 0.659
5.773PheLys: 5.773 ± 1.186
4.885PheLeu: 4.885 ± 1.462
0.0PheMet: 0.0 ± 0.0
5.329PheAsn: 5.329 ± 1.226
0.444PhePro: 0.444 ± 0.405
0.888PheGln: 0.888 ± 0.406
1.332PheArg: 1.332 ± 0.774
3.552PheSer: 3.552 ± 1.287
0.444PheThr: 0.444 ± 0.405
3.552PheVal: 3.552 ± 1.636
1.332PheTrp: 1.332 ± 0.584
2.664PheTyr: 2.664 ± 0.85
0.0PheXaa: 0.0 ± 0.0
Gly
3.996GlyAla: 3.996 ± 1.32
1.332GlyCys: 1.332 ± 1.076
6.661GlyAsp: 6.661 ± 2.359
2.664GlyGlu: 2.664 ± 1.697
3.552GlyPhe: 3.552 ± 1.214
11.989GlyGly: 11.989 ± 4.738
1.332GlyHis: 1.332 ± 0.711
5.773GlyIle: 5.773 ± 1.941
3.552GlyLys: 3.552 ± 0.933
6.661GlyLeu: 6.661 ± 2.113
1.776GlyMet: 1.776 ± 0.81
5.329GlyAsn: 5.329 ± 1.254
0.444GlyPro: 0.444 ± 0.34
3.552GlyGln: 3.552 ± 1.487
2.22GlyArg: 2.22 ± 1.199
7.549GlySer: 7.549 ± 2.936
3.552GlyThr: 3.552 ± 1.342
3.996GlyVal: 3.996 ± 1.536
0.888GlyTrp: 0.888 ± 0.454
4.44GlyTyr: 4.44 ± 1.083
0.0GlyXaa: 0.0 ± 0.0
His
0.444HisAla: 0.444 ± 0.405
0.0HisCys: 0.0 ± 0.0
0.444HisAsp: 0.444 ± 0.505
0.444HisGlu: 0.444 ± 0.34
0.888HisPhe: 0.888 ± 0.809
1.332HisGly: 1.332 ± 0.732
0.888HisHis: 0.888 ± 0.456
1.332HisIle: 1.332 ± 0.663
0.0HisLys: 0.0 ± 0.0
0.444HisLeu: 0.444 ± 0.34
0.444HisMet: 0.444 ± 0.361
0.888HisAsn: 0.888 ± 0.463
0.888HisPro: 0.888 ± 0.559
0.0HisGln: 0.0 ± 0.0
0.444HisArg: 0.444 ± 0.34
0.444HisSer: 0.444 ± 0.361
0.888HisThr: 0.888 ± 0.681
2.664HisVal: 2.664 ± 0.687
0.0HisTrp: 0.0 ± 0.0
0.444HisTyr: 0.444 ± 0.34
0.0HisXaa: 0.0 ± 0.0
Ile
3.996IleAla: 3.996 ± 1.516
0.888IleCys: 0.888 ± 0.427
6.217IleAsp: 6.217 ± 1.546
0.888IleGlu: 0.888 ± 0.406
4.885IlePhe: 4.885 ± 1.483
3.552IleGly: 3.552 ± 1.345
0.888IleHis: 0.888 ± 0.57
3.996IleIle: 3.996 ± 1.739
4.44IleLys: 4.44 ± 1.003
1.776IleLeu: 1.776 ± 0.815
1.776IleMet: 1.776 ± 1.181
4.44IleAsn: 4.44 ± 1.654
2.22IlePro: 2.22 ± 0.764
4.44IleGln: 4.44 ± 1.694
1.776IleArg: 1.776 ± 1.033
7.105IleSer: 7.105 ± 1.057
4.885IleThr: 4.885 ± 1.993
2.22IleVal: 2.22 ± 1.243
0.0IleTrp: 0.0 ± 0.0
2.664IleTyr: 2.664 ± 1.481
0.0IleXaa: 0.0 ± 0.0
Lys
6.217LysAla: 6.217 ± 1.011
0.0LysCys: 0.0 ± 0.0
5.773LysAsp: 5.773 ± 1.812
2.22LysGlu: 2.22 ± 0.917
1.332LysPhe: 1.332 ± 0.751
3.108LysGly: 3.108 ± 0.865
0.888LysHis: 0.888 ± 0.681
3.996LysIle: 3.996 ± 1.138
4.885LysLys: 4.885 ± 1.318
4.885LysLeu: 4.885 ± 1.438
1.332LysMet: 1.332 ± 0.855
2.22LysAsn: 2.22 ± 0.803
2.664LysPro: 2.664 ± 0.927
1.332LysGln: 1.332 ± 1.214
1.332LysArg: 1.332 ± 0.45
7.549LysSer: 7.549 ± 1.165
3.996LysThr: 3.996 ± 1.42
3.996LysVal: 3.996 ± 1.271
0.444LysTrp: 0.444 ± 0.405
1.776LysTyr: 1.776 ± 0.858
0.0LysXaa: 0.0 ± 0.0
Leu
5.329LeuAla: 5.329 ± 1.264
1.332LeuCys: 1.332 ± 0.728
2.22LeuAsp: 2.22 ± 0.85
2.664LeuGlu: 2.664 ± 1.201
3.552LeuPhe: 3.552 ± 1.03
7.993LeuGly: 7.993 ± 3.258
1.776LeuHis: 1.776 ± 0.858
5.329LeuIle: 5.329 ± 1.238
4.44LeuLys: 4.44 ± 1.509
4.885LeuLeu: 4.885 ± 1.819
4.885LeuMet: 4.885 ± 1.452
2.664LeuAsn: 2.664 ± 0.823
3.996LeuPro: 3.996 ± 1.135
2.664LeuGln: 2.664 ± 1.006
1.776LeuArg: 1.776 ± 0.853
8.881LeuSer: 8.881 ± 0.814
8.437LeuThr: 8.437 ± 1.529
7.993LeuVal: 7.993 ± 1.713
0.444LeuTrp: 0.444 ± 0.34
1.776LeuTyr: 1.776 ± 0.645
0.0LeuXaa: 0.0 ± 0.0
Met
2.22MetAla: 2.22 ± 1.014
0.0MetCys: 0.0 ± 0.0
1.332MetAsp: 1.332 ± 0.698
0.888MetGlu: 0.888 ± 0.537
0.888MetPhe: 0.888 ± 0.723
2.22MetGly: 2.22 ± 1.236
0.0MetHis: 0.0 ± 0.0
2.22MetIle: 2.22 ± 1.044
0.888MetLys: 0.888 ± 0.406
1.332MetLeu: 1.332 ± 0.74
0.0MetMet: 0.0 ± 0.0
3.108MetAsn: 3.108 ± 1.043
0.888MetPro: 0.888 ± 0.568
0.444MetGln: 0.444 ± 0.361
2.22MetArg: 2.22 ± 0.979
0.888MetSer: 0.888 ± 0.981
2.22MetThr: 2.22 ± 1.123
0.0MetVal: 0.0 ± 0.0
0.444MetTrp: 0.444 ± 0.34
0.888MetTyr: 0.888 ± 0.718
0.0MetXaa: 0.0 ± 0.0
Asn
3.552AsnAla: 3.552 ± 1.369
0.444AsnCys: 0.444 ± 0.34
3.552AsnAsp: 3.552 ± 1.593
1.776AsnGlu: 1.776 ± 0.793
3.996AsnPhe: 3.996 ± 1.292
4.44AsnGly: 4.44 ± 1.377
0.0AsnHis: 0.0 ± 0.0
2.22AsnIle: 2.22 ± 0.697
1.332AsnLys: 1.332 ± 0.813
4.44AsnLeu: 4.44 ± 1.317
0.0AsnMet: 0.0 ± 0.0
3.996AsnAsn: 3.996 ± 1.258
1.776AsnPro: 1.776 ± 0.7
3.108AsnGln: 3.108 ± 0.612
3.552AsnArg: 3.552 ± 1.122
5.773AsnSer: 5.773 ± 1.79
1.332AsnThr: 1.332 ± 0.758
7.993AsnVal: 7.993 ± 2.915
0.888AsnTrp: 0.888 ± 0.47
1.776AsnTyr: 1.776 ± 0.823
0.0AsnXaa: 0.0 ± 0.0
Pro
2.664ProAla: 2.664 ± 2.087
0.444ProCys: 0.444 ± 0.34
1.776ProAsp: 1.776 ± 0.527
2.22ProGlu: 2.22 ± 0.933
1.332ProPhe: 1.332 ± 0.758
0.888ProGly: 0.888 ± 0.406
0.0ProHis: 0.0 ± 0.0
1.332ProIle: 1.332 ± 0.705
0.444ProLys: 0.444 ± 0.405
3.552ProLeu: 3.552 ± 0.629
0.0ProMet: 0.0 ± 0.0
0.888ProAsn: 0.888 ± 0.652
0.888ProPro: 0.888 ± 0.47
1.332ProGln: 1.332 ± 0.781
1.776ProArg: 1.776 ± 0.632
3.552ProSer: 3.552 ± 1.369
1.776ProThr: 1.776 ± 0.674
4.885ProVal: 4.885 ± 1.881
0.444ProTrp: 0.444 ± 0.361
2.22ProTyr: 2.22 ± 1.164
0.0ProXaa: 0.0 ± 0.0
Gln
3.996GlnAla: 3.996 ± 0.958
0.444GlnCys: 0.444 ± 0.405
1.776GlnAsp: 1.776 ± 0.91
0.444GlnGlu: 0.444 ± 0.505
0.444GlnPhe: 0.444 ± 0.359
0.888GlnGly: 0.888 ± 0.427
0.888GlnHis: 0.888 ± 0.67
3.108GlnIle: 3.108 ± 0.707
2.22GlnLys: 2.22 ± 0.71
3.552GlnLeu: 3.552 ± 0.658
2.664GlnMet: 2.664 ± 0.569
1.332GlnAsn: 1.332 ± 0.676
1.332GlnPro: 1.332 ± 0.612
2.664GlnGln: 2.664 ± 0.874
1.332GlnArg: 1.332 ± 0.412
3.108GlnSer: 3.108 ± 0.846
4.44GlnThr: 4.44 ± 1.716
2.664GlnVal: 2.664 ± 0.855
0.444GlnTrp: 0.444 ± 0.361
1.776GlnTyr: 1.776 ± 0.807
0.0GlnXaa: 0.0 ± 0.0
Arg
0.888ArgAla: 0.888 ± 0.427
0.0ArgCys: 0.0 ± 0.0
1.776ArgAsp: 1.776 ± 0.908
1.332ArgGlu: 1.332 ± 0.611
1.332ArgPhe: 1.332 ± 0.747
0.888ArgGly: 0.888 ± 0.47
0.888ArgHis: 0.888 ± 0.463
3.108ArgIle: 3.108 ± 0.982
2.22ArgLys: 2.22 ± 0.982
7.105ArgLeu: 7.105 ± 1.925
1.332ArgMet: 1.332 ± 0.987
1.776ArgAsn: 1.776 ± 0.578
0.444ArgPro: 0.444 ± 0.359
0.444ArgGln: 0.444 ± 0.405
1.776ArgArg: 1.776 ± 0.534
4.44ArgSer: 4.44 ± 1.469
2.22ArgThr: 2.22 ± 0.725
3.552ArgVal: 3.552 ± 1.581
0.0ArgTrp: 0.0 ± 0.0
0.444ArgTyr: 0.444 ± 0.405
0.0ArgXaa: 0.0 ± 0.0
Ser
7.105SerAla: 7.105 ± 1.67
0.0SerCys: 0.0 ± 0.0
4.44SerAsp: 4.44 ± 1.023
1.332SerGlu: 1.332 ± 0.711
7.549SerPhe: 7.549 ± 1.481
7.549SerGly: 7.549 ± 1.49
2.22SerHis: 2.22 ± 1.172
6.661SerIle: 6.661 ± 1.033
7.549SerLys: 7.549 ± 1.434
7.549SerLeu: 7.549 ± 1.479
0.888SerMet: 0.888 ± 0.981
6.217SerAsn: 6.217 ± 1.532
2.664SerPro: 2.664 ± 1.081
6.217SerGln: 6.217 ± 1.318
1.776SerArg: 1.776 ± 1.172
7.549SerSer: 7.549 ± 2.85
3.552SerThr: 3.552 ± 1.088
11.101SerVal: 11.101 ± 1.612
0.888SerTrp: 0.888 ± 0.718
2.22SerTyr: 2.22 ± 1.291
0.0SerXaa: 0.0 ± 0.0
Thr
3.108ThrAla: 3.108 ± 1.527
1.776ThrCys: 1.776 ± 0.848
3.108ThrAsp: 3.108 ± 0.897
1.332ThrGlu: 1.332 ± 0.905
2.664ThrPhe: 2.664 ± 0.815
8.437ThrGly: 8.437 ± 4.537
0.444ThrHis: 0.444 ± 0.405
2.664ThrIle: 2.664 ± 0.869
3.996ThrLys: 3.996 ± 0.71
3.552ThrLeu: 3.552 ± 0.987
1.776ThrMet: 1.776 ± 0.715
2.22ThrAsn: 2.22 ± 0.593
1.776ThrPro: 1.776 ± 1.01
1.332ThrGln: 1.332 ± 0.686
2.22ThrArg: 2.22 ± 1.093
5.329ThrSer: 5.329 ± 1.206
4.44ThrThr: 4.44 ± 1.602
6.661ThrVal: 6.661 ± 1.337
1.332ThrTrp: 1.332 ± 0.698
0.444ThrTyr: 0.444 ± 0.405
0.0ThrXaa: 0.0 ± 0.0
Val
5.773ValAla: 5.773 ± 1.182
0.888ValCys: 0.888 ± 0.718
3.552ValAsp: 3.552 ± 0.684
3.108ValGlu: 3.108 ± 1.181
5.329ValPhe: 5.329 ± 2.094
4.885ValGly: 4.885 ± 1.088
0.444ValHis: 0.444 ± 0.405
5.329ValIle: 5.329 ± 1.326
4.44ValLys: 4.44 ± 1.209
7.549ValLeu: 7.549 ± 2.565
2.664ValMet: 2.664 ± 0.687
3.552ValAsn: 3.552 ± 1.797
4.44ValPro: 4.44 ± 1.494
2.22ValGln: 2.22 ± 0.942
2.22ValArg: 2.22 ± 0.989
9.769ValSer: 9.769 ± 1.572
7.549ValThr: 7.549 ± 0.964
7.105ValVal: 7.105 ± 1.963
0.0ValTrp: 0.0 ± 0.0
4.44ValTyr: 4.44 ± 1.369
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.444TrpCys: 0.444 ± 0.405
0.444TrpAsp: 0.444 ± 0.405
0.888TrpGlu: 0.888 ± 0.718
0.888TrpPhe: 0.888 ± 0.454
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.888TrpLys: 0.888 ± 0.427
0.444TrpLeu: 0.444 ± 0.361
0.0TrpMet: 0.0 ± 0.0
0.444TrpAsn: 0.444 ± 0.34
0.888TrpPro: 0.888 ± 0.652
0.0TrpGln: 0.0 ± 0.0
0.888TrpArg: 0.888 ± 0.537
0.888TrpSer: 0.888 ± 0.47
0.0TrpThr: 0.0 ± 0.0
0.888TrpVal: 0.888 ± 0.47
0.0TrpTrp: 0.0 ± 0.0
1.776TrpTyr: 1.776 ± 0.525
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.664TyrAla: 2.664 ± 1.169
1.332TyrCys: 1.332 ± 0.801
5.329TyrAsp: 5.329 ± 1.813
2.664TyrGlu: 2.664 ± 1.281
1.776TyrPhe: 1.776 ± 1.009
1.332TyrGly: 1.332 ± 0.667
0.0TyrHis: 0.0 ± 0.0
2.664TyrIle: 2.664 ± 0.79
0.888TyrLys: 0.888 ± 0.67
0.444TyrLeu: 0.444 ± 0.34
0.444TyrMet: 0.444 ± 0.405
1.776TyrAsn: 1.776 ± 0.839
2.22TyrPro: 2.22 ± 1.165
1.332TyrGln: 1.332 ± 0.711
2.22TyrArg: 2.22 ± 0.957
2.22TyrSer: 2.22 ± 1.285
1.776TyrThr: 1.776 ± 0.865
4.44TyrVal: 4.44 ± 0.92
0.0TyrTrp: 0.0 ± 0.0
1.332TyrTyr: 1.332 ± 0.801
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (2253 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski