Amino acid dipepetide frequency for Valsa sordida

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.614AlaAla: 10.614 ± 0.091	1.032AlaCys: 1.032 ± 0.016	4.719AlaAsp: 4.719 ± 0.03	5.562AlaGlu: 5.562 ± 0.047	3.133AlaPhe: 3.133 ± 0.029	6.802AlaGly: 6.802 ± 0.048	1.842AlaHis: 1.842 ± 0.023	4.029AlaIle: 4.029 ± 0.032	4.149AlaLys: 4.149 ± 0.035	7.753AlaLeu: 7.753 ± 0.044	2.168AlaMet: 2.168 ± 0.025	2.996AlaAsn: 2.996 ± 0.026	5.173AlaPro: 5.173 ± 0.046	3.568AlaGln: 3.568 ± 0.032	5.456AlaArg: 5.456 ± 0.043	7.535AlaSer: 7.535 ± 0.052	5.644AlaThr: 5.644 ± 0.042	5.882AlaVal: 5.882 ± 0.04	1.237AlaTrp: 1.237 ± 0.017	2.215AlaTyr: 2.215 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.918CysAla: 0.918 ± 0.017	0.234CysCys: 0.234 ± 0.008	0.643CysAsp: 0.643 ± 0.013	0.574CysGlu: 0.574 ± 0.012	0.488CysPhe: 0.488 ± 0.011	0.938CysGly: 0.938 ± 0.015	0.3CysHis: 0.3 ± 0.007	0.633CysIle: 0.633 ± 0.012	0.461CysLys: 0.461 ± 0.011	1.173CysLeu: 1.173 ± 0.018	0.259CysMet: 0.259 ± 0.008	0.401CysAsn: 0.401 ± 0.009	0.652CysPro: 0.652 ± 0.014	0.4CysGln: 0.4 ± 0.009	0.679CysArg: 0.679 ± 0.012	0.836CysSer: 0.836 ± 0.016	0.624CysThr: 0.624 ± 0.013	0.76CysVal: 0.76 ± 0.012	0.192CysTrp: 0.192 ± 0.007	0.341CysTyr: 0.341 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.065AspAla: 5.065 ± 0.036	0.626AspCys: 0.626 ± 0.011	4.984AspAsp: 4.984 ± 0.05	4.872AspGlu: 4.872 ± 0.041	2.261AspPhe: 2.261 ± 0.024	4.767AspGly: 4.767 ± 0.038	1.319AspHis: 1.319 ± 0.018	2.918AspIle: 2.918 ± 0.024	2.484AspLys: 2.484 ± 0.023	5.123AspLeu: 5.123 ± 0.036	1.444AspMet: 1.444 ± 0.017	1.954AspAsn: 1.954 ± 0.019	3.471AspPro: 3.471 ± 0.028	1.895AspGln: 1.895 ± 0.02	3.155AspArg: 3.155 ± 0.034	4.063AspSer: 4.063 ± 0.035	3.062AspThr: 3.062 ± 0.023	3.908AspVal: 3.908 ± 0.03	0.918AspTrp: 0.918 ± 0.014	1.645AspTyr: 1.645 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.979GluAla: 5.979 ± 0.043	0.591GluCys: 0.591 ± 0.013	4.628GluAsp: 4.628 ± 0.039	5.695GluGlu: 5.695 ± 0.063	1.869GluPhe: 1.869 ± 0.019	4.154GluGly: 4.154 ± 0.033	1.399GluHis: 1.399 ± 0.019	2.751GluIle: 2.751 ± 0.029	3.58GluLys: 3.58 ± 0.033	5.194GluLeu: 5.194 ± 0.039	1.534GluMet: 1.534 ± 0.019	2.102GluAsn: 2.102 ± 0.024	2.917GluPro: 2.917 ± 0.031	2.523GluGln: 2.523 ± 0.026	3.941GluArg: 3.941 ± 0.038	3.876GluSer: 3.876 ± 0.031	3.436GluThr: 3.436 ± 0.027	3.812GluVal: 3.812 ± 0.031	0.882GluTrp: 0.882 ± 0.014	1.628GluTyr: 1.628 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.941PheAla: 2.941 ± 0.026	0.504PheCys: 0.504 ± 0.011	2.272PheAsp: 2.272 ± 0.022	2.111PheGlu: 2.111 ± 0.025	1.489PhePhe: 1.489 ± 0.022	2.845PheGly: 2.845 ± 0.028	0.81PheHis: 0.81 ± 0.013	1.642PheIle: 1.642 ± 0.023	1.454PheLys: 1.454 ± 0.018	3.199PheLeu: 3.199 ± 0.032	0.816PheMet: 0.816 ± 0.015	1.347PheAsn: 1.347 ± 0.019	1.863PhePro: 1.863 ± 0.02	1.309PheGln: 1.309 ± 0.018	1.899PheArg: 1.899 ± 0.02	2.797PheSer: 2.797 ± 0.025	2.048PheThr: 2.048 ± 0.024	2.342PheVal: 2.342 ± 0.022	0.613PheTrp: 0.613 ± 0.013	1.053PheTyr: 1.053 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	6.097GlyAla: 6.097 ± 0.048	0.855GlyCys: 0.855 ± 0.014	4.221GlyAsp: 4.221 ± 0.034	4.064GlyGlu: 4.064 ± 0.03	2.803GlyPhe: 2.803 ± 0.028	7.285GlyGly: 7.285 ± 0.078	1.848GlyHis: 1.848 ± 0.021	3.348GlyIle: 3.348 ± 0.029	3.448GlyLys: 3.448 ± 0.033	6.43GlyLeu: 6.43 ± 0.042	1.763GlyMet: 1.763 ± 0.022	2.601GlyAsn: 2.601 ± 0.028	3.836GlyPro: 3.836 ± 0.038	2.778GlyGln: 2.778 ± 0.024	4.492GlyArg: 4.492 ± 0.039	6.1GlySer: 6.1 ± 0.044	4.253GlyThr: 4.253 ± 0.038	4.639GlyVal: 4.639 ± 0.035	1.208GlyTrp: 1.208 ± 0.017	2.151GlyTyr: 2.151 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.867HisAla: 1.867 ± 0.021	0.311HisCys: 0.311 ± 0.008	1.396HisAsp: 1.396 ± 0.018	1.34HisGlu: 1.34 ± 0.017	0.859HisPhe: 0.859 ± 0.012	1.83HisGly: 1.83 ± 0.022	0.897HisHis: 0.897 ± 0.017	1.119HisIle: 1.119 ± 0.012	0.924HisLys: 0.924 ± 0.016	2.111HisLeu: 2.111 ± 0.02	0.534HisMet: 0.534 ± 0.011	0.81HisAsn: 0.81 ± 0.014	1.58HisPro: 1.58 ± 0.022	0.976HisGln: 0.976 ± 0.016	1.47HisArg: 1.47 ± 0.02	1.654HisSer: 1.654 ± 0.021	1.193HisThr: 1.193 ± 0.015	1.469HisVal: 1.469 ± 0.02	0.33HisTrp: 0.33 ± 0.007	0.672HisTyr: 0.672 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.858IleAla: 3.858 ± 0.033	0.668IleCys: 0.668 ± 0.013	2.689IleAsp: 2.689 ± 0.024	2.672IleGlu: 2.672 ± 0.024	1.762IlePhe: 1.762 ± 0.021	2.991IleGly: 2.991 ± 0.03	1.049IleHis: 1.049 ± 0.016	2.255IleIle: 2.255 ± 0.025	2.077IleLys: 2.077 ± 0.022	4.05IleLeu: 4.05 ± 0.038	1.069IleMet: 1.069 ± 0.017	1.681IleAsn: 1.681 ± 0.019	2.78IlePro: 2.78 ± 0.026	1.726IleGln: 1.726 ± 0.02	2.583IleArg: 2.583 ± 0.024	3.426IleSer: 3.426 ± 0.033	2.693IleThr: 2.693 ± 0.027	2.964IleVal: 2.964 ± 0.027	0.7IleTrp: 0.7 ± 0.013	1.271IleTyr: 1.271 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.501LysAla: 4.501 ± 0.04	0.453LysCys: 0.453 ± 0.01	2.795LysAsp: 2.795 ± 0.029	3.333LysGlu: 3.333 ± 0.037	1.371LysPhe: 1.371 ± 0.017	3.055LysGly: 3.055 ± 0.027	1.102LysHis: 1.102 ± 0.017	2.055LysIle: 2.055 ± 0.025	3.376LysLys: 3.376 ± 0.043	3.823LysLeu: 3.823 ± 0.032	1.065LysMet: 1.065 ± 0.017	1.594LysAsn: 1.594 ± 0.019	2.687LysPro: 2.687 ± 0.025	1.809LysGln: 1.809 ± 0.024	3.268LysArg: 3.268 ± 0.035	3.212LysSer: 3.212 ± 0.03	2.788LysThr: 2.788 ± 0.025	2.826LysVal: 2.826 ± 0.028	0.648LysTrp: 0.648 ± 0.011	1.306LysTyr: 1.306 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.114LeuAla: 8.114 ± 0.054	1.121LeuCys: 1.121 ± 0.016	5.268LeuAsp: 5.268 ± 0.033	5.377LeuGlu: 5.377 ± 0.042	3.033LeuPhe: 3.033 ± 0.029	6.145LeuGly: 6.145 ± 0.041	2.036LeuHis: 2.036 ± 0.024	3.455LeuIle: 3.455 ± 0.033	3.996LeuLys: 3.996 ± 0.037	7.83LeuLeu: 7.83 ± 0.054	1.822LeuMet: 1.822 ± 0.019	2.899LeuAsn: 2.899 ± 0.028	5.334LeuPro: 5.334 ± 0.04	3.598LeuGln: 3.598 ± 0.032	5.619LeuArg: 5.619 ± 0.038	6.758LeuSer: 6.758 ± 0.048	4.565LeuThr: 4.565 ± 0.029	5.573LeuVal: 5.573 ± 0.043	1.197LeuTrp: 1.197 ± 0.015	2.224LeuTyr: 2.224 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.553MetAla: 2.553 ± 0.026	0.241MetCys: 0.241 ± 0.006	1.399MetAsp: 1.399 ± 0.017	1.345MetGlu: 1.345 ± 0.021	0.767MetPhe: 0.767 ± 0.013	1.638MetGly: 1.638 ± 0.019	0.483MetHis: 0.483 ± 0.008	0.966MetIle: 0.966 ± 0.014	1.008MetLys: 1.008 ± 0.014	1.888MetLeu: 1.888 ± 0.023	0.633MetMet: 0.633 ± 0.013	0.783MetAsn: 0.783 ± 0.014	1.407MetPro: 1.407 ± 0.018	0.88MetGln: 0.88 ± 0.015	1.343MetArg: 1.343 ± 0.018	1.972MetSer: 1.972 ± 0.021	1.355MetThr: 1.355 ± 0.016	1.43MetVal: 1.43 ± 0.016	0.293MetTrp: 0.293 ± 0.008	0.557MetTyr: 0.557 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.007AsnAla: 3.007 ± 0.029	0.417AsnCys: 0.417 ± 0.01	1.921AsnAsp: 1.921 ± 0.021	1.926AsnGlu: 1.926 ± 0.022	1.301AsnPhe: 1.301 ± 0.02	3.013AsnGly: 3.013 ± 0.028	0.788AsnHis: 0.788 ± 0.012	1.843AsnIle: 1.843 ± 0.022	1.544AsnLys: 1.544 ± 0.018	3.055AsnLeu: 3.055 ± 0.024	0.869AsnMet: 0.869 ± 0.014	1.538AsnAsn: 1.538 ± 0.024	2.292AsnPro: 2.292 ± 0.022	1.203AsnGln: 1.203 ± 0.018	1.79AsnArg: 1.79 ± 0.017	2.623AsnSer: 2.623 ± 0.025	2.15AsnThr: 2.15 ± 0.023	2.203AsnVal: 2.203 ± 0.025	0.535AsnTrp: 0.535 ± 0.012	1.01AsnTyr: 1.01 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.794ProAla: 5.794 ± 0.058	0.48ProCys: 0.48 ± 0.01	3.45ProAsp: 3.45 ± 0.029	3.896ProGlu: 3.896 ± 0.039	1.978ProPhe: 1.978 ± 0.024	4.52ProGly: 4.52 ± 0.038	1.289ProHis: 1.289 ± 0.017	2.309ProIle: 2.309 ± 0.022	2.599ProLys: 2.599 ± 0.027	4.557ProLeu: 4.557 ± 0.04	1.183ProMet: 1.183 ± 0.018	2.031ProAsn: 2.031 ± 0.025	5.394ProPro: 5.394 ± 0.069	2.56ProGln: 2.56 ± 0.032	3.633ProArg: 3.633 ± 0.036	5.783ProSer: 5.783 ± 0.05	3.879ProThr: 3.879 ± 0.035	3.785ProVal: 3.785 ± 0.034	0.754ProTrp: 0.754 ± 0.012	1.531ProTyr: 1.531 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.703GlnAla: 3.703 ± 0.03	0.421GlnCys: 0.421 ± 0.01	2.183GlnAsp: 2.183 ± 0.022	2.431GlnGlu: 2.431 ± 0.028	1.172GlnPhe: 1.172 ± 0.014	2.584GlnGly: 2.584 ± 0.027	1.108GlnHis: 1.108 ± 0.02	1.67GlnIle: 1.67 ± 0.02	1.874GlnLys: 1.874 ± 0.02	3.313GlnLeu: 3.313 ± 0.032	0.917GlnMet: 0.917 ± 0.014	1.432GlnAsn: 1.432 ± 0.022	2.66GlnPro: 2.66 ± 0.035	2.745GlnGln: 2.745 ± 0.048	2.609GlnArg: 2.609 ± 0.026	2.881GlnSer: 2.881 ± 0.032	2.171GlnThr: 2.171 ± 0.023	2.233GlnVal: 2.233 ± 0.023	0.554GlnTrp: 0.554 ± 0.011	1.103GlnTyr: 1.103 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.014ArgAla: 5.014 ± 0.036	0.66ArgCys: 0.66 ± 0.013	3.549ArgAsp: 3.549 ± 0.035	3.867ArgGlu: 3.867 ± 0.038	2.026ArgPhe: 2.026 ± 0.022	4.057ArgGly: 4.057 ± 0.036	1.6ArgHis: 1.6 ± 0.021	2.689ArgIle: 2.689 ± 0.026	3.381ArgLys: 3.381 ± 0.033	5.475ArgLeu: 5.475 ± 0.039	1.386ArgMet: 1.386 ± 0.017	2.145ArgAsn: 2.145 ± 0.023	3.725ArgPro: 3.725 ± 0.032	2.64ArgGln: 2.64 ± 0.027	5.331ArgArg: 5.331 ± 0.046	4.585ArgSer: 4.585 ± 0.042	3.181ArgThr: 3.181 ± 0.024	3.406ArgVal: 3.406 ± 0.029	0.932ArgTrp: 0.932 ± 0.014	1.608ArgTyr: 1.608 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.797SerAla: 6.797 ± 0.052	0.801SerCys: 0.801 ± 0.013	4.143SerAsp: 4.143 ± 0.037	3.923SerGlu: 3.923 ± 0.031	2.773SerPhe: 2.773 ± 0.025	5.883SerGly: 5.883 ± 0.039	1.801SerHis: 1.801 ± 0.021	3.607SerIle: 3.607 ± 0.032	3.457SerLys: 3.457 ± 0.03	6.64SerLeu: 6.64 ± 0.043	1.789SerMet: 1.789 ± 0.021	2.796SerAsn: 2.796 ± 0.026	5.515SerPro: 5.515 ± 0.054	3.151SerGln: 3.151 ± 0.027	4.814SerArg: 4.814 ± 0.042	8.704SerSer: 8.704 ± 0.08	5.369SerThr: 5.369 ± 0.043	4.485SerVal: 4.485 ± 0.033	1.071SerTrp: 1.071 ± 0.015	2.045SerTyr: 2.045 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.58ThrAla: 5.58 ± 0.04	0.702ThrCys: 0.702 ± 0.012	2.945ThrAsp: 2.945 ± 0.028	3.072ThrGlu: 3.072 ± 0.021	2.146ThrPhe: 2.146 ± 0.022	4.404ThrGly: 4.404 ± 0.038	1.209ThrHis: 1.209 ± 0.017	2.866ThrIle: 2.866 ± 0.026	2.557ThrLys: 2.557 ± 0.024	4.831ThrLeu: 4.831 ± 0.036	1.267ThrMet: 1.267 ± 0.017	2.063ThrAsn: 2.063 ± 0.025	4.285ThrPro: 4.285 ± 0.039	2.03ThrGln: 2.03 ± 0.022	3.117ThrArg: 3.117 ± 0.028	5.199ThrSer: 5.199 ± 0.048	4.549ThrThr: 4.549 ± 0.044	3.864ThrVal: 3.864 ± 0.037	0.862ThrTrp: 0.862 ± 0.016	1.605ThrTyr: 1.605 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.717ValAla: 5.717 ± 0.037	0.796ValCys: 0.796 ± 0.014	4.044ValAsp: 4.044 ± 0.028	3.989ValGlu: 3.989 ± 0.032	2.438ValPhe: 2.438 ± 0.024	4.213ValGly: 4.213 ± 0.037	1.379ValHis: 1.379 ± 0.017	2.829ValIle: 2.829 ± 0.027	2.873ValLys: 2.873 ± 0.027	5.692ValLeu: 5.692 ± 0.042	1.388ValMet: 1.388 ± 0.017	2.145ValAsn: 2.145 ± 0.021	3.77ValPro: 3.77 ± 0.032	2.369ValGln: 2.369 ± 0.026	3.554ValArg: 3.554 ± 0.029	4.563ValSer: 4.563 ± 0.034	3.675ValThr: 3.675 ± 0.031	4.69ValVal: 4.69 ± 0.032	0.901ValTrp: 0.901 ± 0.016	1.79ValTyr: 1.79 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.225TrpAla: 1.225 ± 0.018	0.197TrpCys: 0.197 ± 0.006	0.977TrpAsp: 0.977 ± 0.017	0.867TrpGlu: 0.867 ± 0.017	0.527TrpPhe: 0.527 ± 0.012	0.968TrpGly: 0.968 ± 0.016	0.358TrpHis: 0.358 ± 0.009	0.671TrpIle: 0.671 ± 0.013	0.745TrpLys: 0.745 ± 0.012	1.33TrpLeu: 1.33 ± 0.018	0.389TrpMet: 0.389 ± 0.009	0.598TrpAsn: 0.598 ± 0.011	0.632TrpPro: 0.632 ± 0.013	0.554TrpGln: 0.554 ± 0.011	0.947TrpArg: 0.947 ± 0.013	1.02TrpSer: 1.02 ± 0.016	0.93TrpThr: 0.93 ± 0.013	0.909TrpVal: 0.909 ± 0.014	0.285TrpTrp: 0.285 ± 0.009	0.442TrpTyr: 0.442 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.165TyrAla: 2.165 ± 0.026	0.4TyrCys: 0.4 ± 0.01	1.707TyrAsp: 1.707 ± 0.02	1.58TyrGlu: 1.58 ± 0.018	1.157TyrPhe: 1.157 ± 0.018	2.127TyrGly: 2.127 ± 0.028	0.722TyrHis: 0.722 ± 0.012	1.309TyrIle: 1.309 ± 0.019	1.077TyrLys: 1.077 ± 0.015	2.498TyrLeu: 2.498 ± 0.023	0.646TyrMet: 0.646 ± 0.011	1.11TyrAsn: 1.11 ± 0.016	1.431TyrPro: 1.431 ± 0.017	1.051TyrGln: 1.051 ± 0.015	1.558TyrArg: 1.558 ± 0.017	1.972TyrSer: 1.972 ± 0.024	1.587TyrThr: 1.587 ± 0.02	1.637TyrVal: 1.637 ± 0.02	0.46TyrTrp: 0.46 ± 0.01	0.956TyrTyr: 0.956 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.002

Statistics based on 9818 proteins (4954655 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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